Tsukamoto Hirokazu 塚本裕一

… Alternative Names

TSUKAMOTO Hirokazu 塚本裕一

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Researcher Number	70323037
Other IDs	https://orcid.org/0000-0002-7849-6427
Affiliation (Current)	2024: 横浜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 横浜薬科大学, 薬学部, 教授 2016 – 2017: 東北大学, 薬学研究科, 講師 2014 – 2015: 東北大学, 薬学研究科(研究院), 講師 2012 – 2013: 東北大学, 薬学研究科(研究院), 助教 2008: 東北大, 薬学研究科(研究院), 助教 … More 2007: Tohoku University, 大学院・薬学研究科, 助教 2004 – 2006: 東北大学, 大学院・薬学研究科, 助手 2005: 東北大学, 大学院薬学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Chemical pharmacy / Basic Section 33020:Synthetic organic chemistry-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Science and Engineering / Chemical pharmacy
Keywords	Principal Investigator パラジウム触媒 / アリールボロン酸 / 共役エンイン / アレン / パラジウム / 二重水素結合供与 / イミニウム中間体 / α,β－不飽和アルデヒド / 1,8-ジヒドロキシナフタレン / 9-ヒドロキシフェナレノン … More / ヒドロアルキル化反応 / 光学活性アレン / 1,3-アルカジエン / ヒドロアリール化 / ヒドロアルキル化 / プロ求核剤 / 中心不斉 / 軸不斉 / キラルブレンステッド酸 / アレニルホスフェートの動的速度論的分割反応 / ジインの非対称化 / パラジウム－ジフェニルプロリノール共触媒 / アルキン－エナール / キラルルイス酸 / 有機亜鉛試薬 / アルキン－カルボニル / エナンチオ選択的アンチWacker型環化反応 / アレニルアルコール / アルキン / 不斉合成 / haouamine B / 環化メカニズム / 置換基効果 / 位置選択性 / ホスフィン配位子 / haouamine / ハオウアミン / トランスメタル化 / 有機ボロン酸 / 環化機構 / アンチWacker型環化反応 / バラジウム触媒 / 有機ホウ素試薬 / 環状化合物 / 酸化的付加 / アンチWacker / 固相合成 / カンプトテシン / キノリン環 / 芳香族C-H結合活性化 / イリジウム触媒 … More Except Principal Investigator 固相合成 / 不斉合成 / 環化反応 / 反応集積化 / フロー合成 / 非天然型アミノ酸 / 環状ペプチド / 中分子 / fluorous synthesis / compound library / bisindole / catalysis / solid-phase synthesis / immobilization / organometallics / indole / 核磁気共鳴 / 構造解析 / 生理活性 / 有機ホウ素 / パラジウム触媒 / 金属錯体 / 高分子 / フルオラス / ライブラリー / ビスインドール / 触媒反応 / 固定化 / 有機金属 / インドール Less

Catalytic synthesis of phenalenones using the double hydrogen-bond donating ability of iminium intermediatesPrincipal Investigator
- Principal Investigator
  
  塚本裕一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Yokohama College of Pharmacy
Asymmetric Hydroalkylation of Conjugate Enynes with Pronucleophiles Leading to Optically Active AllenesPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Hirokazu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Yokohama College of Pharmacy
Development of enantioselective 'anti-Wacker'-type cyclizationsPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University
Middle-size cyclic peptides containing unnatural amino acids enable the control of higher cell function
- Principal Investigator
  
  DOI TAKAYUKI
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Mechanistic study on anti-Wacker-type cyclization and application to synthesis of biologically active polycyclic compoundsPrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Hirokazu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University
アンチWacker型環化反応の機構解析および多環式生物活性物質合成への応用Principal Investigator
- Principal Investigator
  
  塚本裕一
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University
パラジウム触媒へのアンチWacker型酸化的付加による新規環状化合物合成法の開発Principal Investigator
- Principal Investigator
  
  塚本裕一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University
イリジウム触媒を利用した芳香族C-H結合活性化によるキノリン環合成法の開発Principal Investigator
- Principal Investigator
  
  塚本裕一
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University
Synthesis of bisindole derivatives using immobilized indolylmetal compounds
- Principal Investigator
  
  KONDO Yoshinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University

[Journal Article] Scalable Total Syntheses and Structure‐Activity Relationships of Haouamine A, B, and their Derivatives as Stable Formate Salts2020
- Author(s)
  Hirokazu Tsukamoto, Saki Nakamura, Akito Tomida, Takayuki Doi
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 26 Issue: 55 Pages: 12528-12532
- DOI
  10.1002/chem.202001756
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Key Factors for High Diastereo- and Enantioselectivity of Umpolung Cyclizations of Aldehyde-Containing Allylpalladium Intermediates2019
- Author(s)
  Tsukamoto Hirokazu、Kawase Ayumu、Omura Hirotaka、Doi Takayuki
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 92 Issue: 10 Pages: 1743-1753
- DOI
  10.1246/bcsj.20190167
- NAID
  130007728663
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Palladium‐Catalyzed Umpolung Type‐II Cyclization of Allylic Carbonate‐Aldehydes Leading to 3‐Methylenecycloalkanol Derivatives2019
- Author(s)
  Tsukamoto Hirokazu、Kawase Ayumu、Doi Takayuki
- Journal Title
  
  Advanced Synthesis & Catalysis
  
  Volume: 361 Issue: 16 Pages: 3733-3738
- DOI
  10.1002/adsc.201900450
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Palladium(0)－Lithium Iodide Cocatalyzed Asymmetric Hydroalkylation of Conjugated Enynes with Pronucleophiles Leading to 1,3-Disubstituted Allenes2019
- Author(s)
  Hirokazu Tsukamoto, Tatsuya Konno, Kazuya Ito, and Takayuki Doi
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 17 Pages: 6811-6814
- DOI
  10.1021/acs.orglett.9b02439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06966, KAKENHI-PLANNED-15H05837
[Journal Article] First Total Synthesis of Palmarumycin C6 based on Double Oxa-Michael Addition of 1,8-Dihydroxynaphthalene to 3-Bromo-1-indenone2019
- Author(s)
  Doi Takayuki、Tsukamoto Hirokazu、Nomura Yumi
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Issue: 1 Pages: 549-565
- DOI
  10.3987/com-18-s(f)52
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Palladium(0)-catalyzed [4+2] Annulation of Salicylaldehydes and Propargyl Carbonates to Produce 3,4-Dihydro-2-methylene-2H-1-benzopyran-4-ols2019
- Author(s)
  Kawase Ayumu、Omura Hirotaka、Doi Takayuki、Tsukamoto Hirokazu
- Journal Title
  
  Chemistry Letters
  
  Volume: 48 Issue: 11 Pages: 1402-1405
- DOI
  10.1246/cl.190642
- NAID
  130007741835
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Total Synthesis of Spiromamakone A and Structure Revision of Spiropreussione A2018
- Author(s)
  H. Tsukamoto, S.Hanada, Y. Nomura, T. Doi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 16 Pages: 9430-9441
- DOI
  10.1021/acs.joc.8b01075
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] onjugate Addition to Acylketene Acetals Derived from 1,8-Dihydroxynaphthalene and Its Application To Synthesize the Proposed Structure of Spiropreussione A2018
- Author(s)
  H. Tsukamoto, Y. Nomura, K. Fujiwara, S. Hanada, T. Doi
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 10 Pages: 3140-3143
- DOI
  10.1021/acs.orglett.8b01259
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Synthesis of multiple-substituted dihydrofurans via palladium-catalysed coupling between 2,3-alkadienols and pronucleophiles2018
- Author(s)
  Hirokazu Tsukamoto, Kazuya Ito, Takayuki Doi
- Journal Title
  
  Chem. Commun.
  
  Volume: 54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07849
[Journal Article] A total synthesis and biological evaluation of siladenoserinol A and its analogues2018
- Author(s)
  M. Yoshida, K. Saito, H. Kato, S. Tsukamoto, T. Doi
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 印刷中 Issue: 18 Pages: 5147-5150
- DOI
  10.1002/anie.201801659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03994, KAKENHI-PROJECT-17H04646, KAKENHI-PLANNED-15H05837
[Journal Article] Synthesis of Spiromamakone A Benzo Analogues via Double Oxa-Michael Addition of 1,8-Dihydroxynaphthalene2016
- Author(s)
  Tsukamoto, H.; Hanada, S.; Kumasaka, K.; Kagaya, N.; Izumikawa, M.; Shin-ya, K.; Doi, T.
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Issue: 19 Pages: 4848-4851
- DOI
  10.1021/acs.orglett.6b02328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07849
[Journal Article] Total Synthesis and Structure Determination of JBIR-108 - A 2-Hydroxy-2-(1-hydroxyethyl)-2,3-dihydro-3(2H)-furanone Isolated from Streptomyces gramineus IR087Pi-42015
- Author(s)
  Fujiwara, Koichi; Tsukamoto, Hirokazu; Izumikawa, Miho; Hosoya, Takahiro; Kagaya, Noritaka; Takagi, Motoki; Yamamura, Hideki; Hayakawa, Masayuki; Shin-ya, Kazuo; Doi, Takayuki
- Journal Title
  
  Journal of Organic Chemistry
  
  Volume: 80 Issue: 1 Pages: 114-132
- DOI
  10.1021/jo502198y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590004, KAKENHI-PROJECT-15K07849
[Journal Article] Asymmetric Palladium-Catalyzed Umpolung Cyclization of Allylic Acetate-Aldehyde using Formate as a Reductant2015
- Author(s)
  Tsukamoto, Hirokazu; Kawase, Ayumu; Doi, Takayuki
- Journal Title
  
  Chemical Communications
  
  Volume: 2015 Issue: 38 Pages: 8027-8030
- DOI
  10.1039/c5cc02176f
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590004, KAKENHI-PROJECT-15K07849
[Journal Article] Reconstitution of Peptidoglycan Cross-Linking Leads to Improved Fluorescent Probes of Cell Wall Synthesis2014
- Author(s)
  Lebar, Matthew D.; May, Janine M.; Meeske, Alexander J.; Leiman, Sara A.; Lupoli, Tania J.; Tsukamoto, Hirokazu; Losick, Richard; Rudner, David Z.; Walker, Suzanne; Kahne, Daniel
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 136 Issue: 31 Pages: 10874-10877
- DOI
  10.1021/ja505668f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590004
[Journal Article] Hg<sup>2+</sup>-Trapping Beads: Hg<sup>2+</sup>-Specific Recognition through Thymine–Hg(II)–Thymine Base Pairing2014
- Author(s)
  栗山光博、他12名
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 7 Pages: 709-712
- DOI
  10.1248/cpb.c13-00918
- NAID
  130004053812
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J07758, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-24590004, KAKENHI-PROJECT-25460002
[Journal Article] Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction2014
- Author(s)
  Qiao, Yuan; Lebar, Matthew D.; Schirner, Kathrin; Schaefer, Kaitlin; Tsukamoto, Hirokazu; Kahne, Daniel; Walker, Suzanne
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 136 Issue: 42 Pages: 14678-14681
- DOI
  10.1021/ja508147s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590004
[Journal Article] Alternate Mode of Palladium-Catalyzed Alkynyliminium Ion Cyclizations Affording Stereodefined N-Alkyl-3-alkylidenepyrrolidines2013
- Author(s)
  Hirokazu Tsukamoto,* Mitsugu Shiraishi, and Takayuki Doi
- Journal Title
  
  ORGANIC LETTERS
  
  Volume: 15 Issue: 23 Pages: 5932-5935
- DOI
  10.1021/ol402685g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590004
[Journal Article] Forming Cross-Linked Peptidoglycan from Synthetic Gram-Negative Lipid II2013
- Author(s)
  Lebar, M. D.; Lupoli, T. J.; Tsukamoto, H.; May, J. M.; *Walker, S.; *Kahne, D.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 12 Pages: 4632-4635
- DOI
  10.1021/ja312510m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590004
[Journal Article] Tuning the Moenomycin Pharmacophore To Enable Discovery of Bacterial Cell Wall Synthesis Inhibitors2013
- Author(s)
  Gampe, C. M.; Tsukamoto, H.; Doud, E. H.; *Walker, S.; *Kahne, D.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 10 Pages: 3776-3779
- DOI
  10.1021/ja4000933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590004
[Journal Article] Enantioselective Arylative Cyclization of Allenyl Aldehydes with Arylboronic Acids under Pd(II)-diphosphine Catalysis2008
- Author(s)
  Tsukamoto, H.; Matsumoto, T.; Kondo, Y.
- Journal Title
  
  Org. Lett. 10
  
  Pages: 1047-1050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790003
[Journal Article] Microwave-Assisted Palladium(0)-Catalyzed Alkylative Cyclization of Allenyl Aldehydes Leading to 3-Substituted 3-Cycloalken-1-ols2008
- Author(s)
  Tsukamoto, H.; Matsumoto, T.; Kondo, Y.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 388-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790003
[Journal Article] Palladium(0)-Catalyzed Regioselective and Multicomponent Synthesis of 1,2,3-Trisubstituted 1H-Indenes2007
- Author(s)
  Tsukamoto, H.; Ueno, T.; Kondo, Y.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 3033-3036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790003
[Journal Article] Palladium(II)-Catalyzed Annulation of Alkynes with ortho-Ester-Containing Phenylboronic Acids2007
- Author(s)
  Tsukamoto, H.; Kondo, Y.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 4227-4230
- NAID
  130006996033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790003
[Journal Article] Remarkable solvent effect on Pd(0)-catalyzed deprotection of allyl ethers using barbituric acid derivatives: application to selective and successive removal of allyl, methallyl, and prenyl ethers2007
- Author(s)
  Tsukamoto, H.; Suzuki, T.; Kondo, Y.
- Journal Title
  
  Synlett
  
  Pages: 3131-3136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790003
[Journal Article] Chromatography-free Pd-catalyzed deprotection of allyl ethers using PS-DEAM as a scavenger of boronic acids and Pd catalyst2007
- Author(s)
  Tsukamoto, H.; Suzuki, T.; Kondo, Y.
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 8438-8441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790003
[Journal Article] Palladium-catalyzed alkylative cyclization of alkynals and alkynones : Remarkable trans-sddition of organoboronic reagents2006
- Author(s)
  H.Tsukamoto, T.Ueno, Y.Kondo
- Journal Title
  
  Journal of the American Chemical Society 128 (5)
  
  Pages: 1406-1407
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390002
[Journal Article] Palladium-catalyzed alkylative cyclization of alkynals and alkynones : Remarkable tras-addition of organoboronic reagents2006
- Author(s)
  H.Tsukamoto, T.Ueno, Y.Kondo
- Journal Title
  
  Journal of American Chemical Society 128(5)
  
  Pages: 1406-1407
- Data Source
  KAKENHI-PROJECT-16390002
[Journal Article] Revisiting benzenesulfonyl linker for the deoxygenation and multifunctionalization of phenols2006
- Author(s)
  Tsukamoto, H., Suzuki, R., Kondo, Y.
- Journal Title
  
  Journal of Combinatorial Chemistry 8(in press)
- Data Source
  KAKENHI-PROJECT-16790004
[Journal Article] Palladium-catalyzed alkylative cyclization of alkynals and alkynones : Remarkable trans-sddition of organoboronic reagents2006
- Author(s)
  H.Tsukamoto, T.Ueno, Y.Kondo
- Journal Title
  
  Journal of the American Chemical Society 128(5)
  
  Pages: 1406-1407
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390002
[Journal Article] Palladium(0)-Catalyzed Direct Cross-Coupling Reaction of Allyl Alcohols with Aryl- and Vinylboronic Acids2004
- Author(s)
  H.Tsukamoto, M.Sato, Y.Kondo
- Journal Title
  
  Chem.Commun.
  
  Pages: 1200-1201
- Data Source
  KAKENHI-PROJECT-16390002
[Presentation] パラジウム触媒とアリールボロン酸を用いた共役エンインの位置および立体選択的ヒドロアリール化反応の開発2023
- Author(s)
  塚本裕一、米沢勇吾、金野達也、土井隆行
- Organizer
  日本薬学会第143年会（札幌）
- Data Source
  KAKENHI-PROJECT-19K06966
[Presentation] 1,8-ジヒドロキシナフタレンとイナールを用いた9-ヒドロキシフェナレノンの触媒的合成法の開発2022
- Author(s)
  塚本裕一、池田彩音、中村純、鈴木恵子、野村友美、土井隆行
- Organizer
  第66回日本薬学会関東支部大会（横浜）
- Data Source
  KAKENHI-PROJECT-22K05102
[Presentation] パラジウム触媒とアリールボロン酸を用いた共役エンインのアンチ選択的ヒドロアリール化反応の開発2022
- Author(s)
  塚本裕一、米沢勇吾、金野達也、土井隆行
- Organizer
  第66回日本薬学会関東支部大会（横浜）
- Data Source
  KAKENHI-PROJECT-19K06966
[Presentation] 光学活性なシクロヘキセノンのβ脱離を利用したhaouamine類の全合成研究2019
- Author(s)
  塚本裕一、富田昂仁、中村早希、土井隆行
- Organizer
  第116回有機合成シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 0 価パラジウム触媒を用いた共役エンインのヒドロアルキル化反応による中心不斉を有するアレン合成法の開発2019
- Author(s)
  伊藤和也、金野達也、土井隆行、塚本裕一
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-19K06966
[Presentation] 0価パラジウム触媒を用いた共役エンインのヒドロアルキル化反応による光学活性アレン合成法の開発2019
- Author(s)
  伊藤和也，金野達也，土井隆行，塚本裕一
- Organizer
  第45回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06966
[Presentation] パラジウム/キラルアミン共触媒を用いたアルキン－エナール化合物のエナンチオ選択的付加・環化反応の開発2019
- Author(s)
  伊藤和也、塚本裕一、土井隆行
- Organizer
  第115回有機合成シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06966
[Presentation] パラジウム/キラルアミン共触媒を用いたアルキン－エナール化合物のエナンチオ選択的付加・環化反応の開発2019
- Author(s)
  伊藤和也、塚本裕一、土井隆行
- Organizer
  薬懇話会2019 in 秋保
- Data Source
  KAKENHI-PROJECT-19K06966
[Presentation] 0価パラジウム触媒を用いた共役エンインのヒドロアルキル化反応による光学活性アレン合成法の開発2019
- Author(s)
  伊藤和也，金野達也，土井隆行，塚本裕一
- Organizer
  第45回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 0価パラジウム触媒を用いたアレニックアルコールとpronucleophileの直接的カップリング反応2017
- Author(s)
  ○伊藤和也，塚本裕一，土井隆行
- Organizer
  第64回有機金属化学討論会
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 分子内にカルボニル基を有する共役エンイン化合物のアンチWacker型環化反応2017
- Author(s)
  ○伊藤和也，塚本裕一，土井隆行
- Organizer
  第111回有機合成シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] スピロママコンAおよび類縁体の合成研究2017
- Author(s)
  ○塚本裕一，花田祥吾，熊坂幸一，土井隆行
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] ０価パラジウム触媒を用いたアレニックアルコールとPronucleophileの直接的カップリング反応2017
- Author(s)
  塚本裕一、伊藤和也、土井隆行
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] ０価パラジウム触媒を用いた共役エンインのアレンおよび1,3-ジエンへの変換反応の開発2017
- Author(s)
  塚本裕一、金野達也、伊藤和也、土井隆行
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] ダブルオキサMichael反応を用いたpalmarumycin C6の合成研究2017
- Author(s)
  塚本裕一、野村友美、土井隆行
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] スピロママコンAの全合成2017
- Author(s)
  塚本裕一、花田祥吾、土井隆行
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] パラジウム触媒を用いた共役エンインに対するPronucleophileの付加反応による1,3-二置換アレンの合成2017
- Author(s)
  塚本裕一，○金野達也，伊藤和也，土井隆行
- Organizer
  第64回有機金属化学討論会
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Spiropreussione A提唱構造の全合成2017
- Author(s)
  塚本裕一，○野村友美，藤原広一，土井隆行
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Spiropreussione A提唱構造の全合成2017
- Author(s)
  塚本裕一，野村友美，藤原広一，土井隆行
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] パラジウム触媒を用いた共役エンインに対するPronucleophileの付加反応による1,3-二置換アレンの合成2017
- Author(s)
  塚本裕一，○金野達也，伊藤和也，土井隆行
- Organizer
  第34回有機合成化学セミナー
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] アシルケテンセターへの共役付加を用いた spiropreussione A提唱構造の全合成2017
- Author(s)
  塚本裕一，○野村友美，藤原広一，土井隆行
- Organizer
  第56回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] スピロママコンAおよび類縁体の合成研究2017
- Author(s)
  塚本裕一，花田祥吾，熊坂幸一，土井隆行
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 分子内カルボニル基を有する共役エンイン化合物のアンチWacker型環化反応2016
- Author(s)
  塚本裕一、伊藤和也、土井隆行
- Organizer
  第27回万有仙台シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Spiromamakone Aの合成研究2016
- Author(s)
  塚本裕一、花田祥吾、熊坂幸一、土井隆行
- Organizer
  第55回日本薬学会東北支部大会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 共役付加を利用したナフタレンアセタール構築法の開発2016
- Author(s)
  塚本裕一，野村友美，藤原広一，花田祥吾，土井隆行
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 分子内カルボニル基を有する共役エンイン化合物のアンチWacker型環化反応2016
- Author(s)
  塚本裕一、伊藤和也、土井隆行
- Organizer
  第55回日本薬学会東北支部大会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Spiromamakone Aの合成研究2016
- Author(s)
  塚本裕一、花田祥吾、熊坂幸一、土井隆行
- Organizer
  第109回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2016-06-08
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 二価パラジウム触媒を用いた多置換2-ナフタレンアミン合成法の開発2016
- Author(s)
  塚本裕一，池田大志，土井隆行
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] パラジウム触媒を用いた炭酸アリルエステル－アルデヒドのタイプII 極性転換環化反応の開発2016
- Author(s)
  川瀬歩，塚本裕一，土井隆行
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 0価パラジウム触媒を用いた7-エン-5-イン-アルデヒドのアンチWacker型環化反応の開発2016
- Author(s)
  塚本裕一，伊藤和也，土井隆行
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Construction of naphthalene acetal via conjugate addition2016
- Author(s)
  塚本裕一、野村友美、藤原広一、花田祥吾、土井隆行
- Organizer
  平成28年度化学系学協会東北大会
- Place of Presentation
  いわき市
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 分子内カルボニル基を有する共役エンイン化合物のアンチWacker型環化反応2016
- Author(s)
  塚本裕一、伊藤和也、土井隆行
- Organizer
  第63回有機金属化学討論会
- Place of Presentation
  東京
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] アリルパラジウム中間体を求核剤として用いるアルデヒドの分子内アリル化反応2016
- Author(s)
  川瀬歩、塚本裕一、土井隆行
- Organizer
  第14回次世代を担う有機化学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Synthesis of Substituted Pyridines via 'Anti-Wacker'-type Cyclization2015
- Author(s)
  Tsukamoto, H.; Ito, K.; Doi, T.
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  青森
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Synthetic Studies of Spiromamakone A2015
- Author(s)
  Tsukamoto, H.; Hanada, S.; Kumasaka, K.; Doi, T.
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  青森
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Concise formal synthesis of haouamine family using palladium-catalyzed arylative cyclization2015
- Author(s)
  Tsukamoto, H.; Nakamura, S.; Doi, T.
- Organizer
  International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Haouamine A, B および類縁体の効率的合成法の開発2015
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  第41回反応と合成の進歩シンポジウム
- Place of Presentation
  東大阪
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] Total synthesis and structure determination of JBIR-1082015
- Author(s)
  Fujiwara, K.; Tsukamoto, H.; Doi, T.
- Organizer
  14th International Conference on the Chemistry of Antibiotics and other Bioactive Compounds
- Place of Presentation
  Texas, USA
- Year and Date
  2015-10-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07849
[Presentation] 二価パラジウム触媒を用いた多置換β―ナフチルアミン合成法の開発2014
- Author(s)
  塚本裕一，池田大志，土井隆行
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  福島
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アンチWacker型環化反応を用いたhaouamine誘導体の合成研究2014
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  福島
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アンチWacker型環化反応を用いたハオウアミン類縁体の合成研究2014
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] Palladium-Catalyzed Alkynyl Iminium Ion Cyclizations Leading to 1,2,3,6-Tetrahydropyridines and 3-Alkylidenepyrrolidines2013
- Author(s)
  Hirokazu Tsukamoto, Mitsugu Shiraishi, Takayuki Doi
- Organizer
  The 23rd French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  Nagasaki, Japan
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] Palladium-Catalyzed Alkynyl Iminium Ion Cyclizations Leading to 1,2,3,6-Tetrahydropyridines and 3-Alkylidenepyrrolidines2013
- Author(s)
  Hirokazu Tsukamoto, Mitsugu Shiraishi, Takayuki Doi
- Organizer
  4th UK/Japan Conference in Catalytic Asymmetric Synthesis
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] ０価パラジウム触媒を用いた三成分連結反応による含窒素複素環化合物の選択的合成法2013
- Author(s)
  塚本裕一，白石貢，土井隆行
- Organizer
  第１０３回有機合成シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] Synthetic Study on Haouamine Derivatives Using ‘Anti-Wacker’-Type Cyclizaiton2013
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  平成２５年度　化学系学協会東北大会及び日本化学会東北支部７０周年記念国際会議
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] JBIR-108の全合成研究2013
- Author(s)
  藤原広一，塚本裕一，土井隆行
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] Palladium-Catalyzed Alkynyl Iminium Ion Cyclizations Leading to 1,2,3,6-Tetrahydropyridines and 3-Alkylidenepyrrolidines2013
- Author(s)
  塚本裕一，白石貢，土井隆行
- Organizer
  第６０回有機金属化学討論会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アンチWacker型環化反応を用いたhaouamine誘導体の合成研究2013
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  第１０４回有機合成シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アリルパラジウム中間体を求核剤とするアルデヒドの触媒的分子内不斉アリル化反応2012
- Author(s)
  塚本裕一，川瀬歩，土井隆行
- Organizer
  平成２４年度　化学系学協会東北大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] ２－アルキル－２－ヒドロキシ－３－フラノン骨格構築法の開発およびE-492類の全合成研究2012
- Author(s)
  藤原広一，塚本裕一，土井隆行
- Organizer
  第１０２回有機合成シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] パラジウム触媒を用いた３－アルキリデンピロリジンの立体選択的合成法の開発2012
- Author(s)
  塚本裕一，白石貢，土井隆行
- Organizer
  第４２回複素環化学討論会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] NADHフマル酸還元酵素阻害活性を有するE-492類の全合成研究2012
- Author(s)
  藤原広一，塚本裕一，土井隆行
- Organizer
  平成２４年度　化学系学協会東北大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アルキニルケトンの付加・環化反応を利用した多置換ピリジン合成法の開発2012
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  第４２回複素環化学討論会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アンチWacker型環化反応による置換ピペリジン合成法の開発2008
- Author(s)
  塚本裕一・根東義則
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18790003
[Presentation] 2価パラジウム触媒を用いた内部アルキンとエステル基含有フェニルボロン酸のカップリング反応2007
- Author(s)
  塚本裕一・根東義則
- Organizer
  第33回反応と合成の進歩シンポジウム
- Place of Presentation
  長崎市
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18790003
[Presentation] Preparation of 3-Cycloalken-1-Ols by Palladium (0)-Catalyzed 'Anti-Wacker'-Type Alkylative Cyclization of Allenyl Aldehydes2007
- Author(s)
  塚本裕一・松本友孝・根東義則
- Organizer
  OMCOS14
- Place of Presentation
  奈良市
- Year and Date
  2007-08-05
- Data Source
  KAKENHI-PROJECT-18790003
[Presentation] マイクロ波を利用したアレナール類のアンチWacker型環化反応2007
- Author(s)
  塚本裕一・松本友孝・根東義則
- Organizer
  第54回有機金属化学討論会
- Place of Presentation
  東広島市
- Year and Date
  2007-10-29
- Data Source
  KAKENHI-PROJECT-18790003
[Presentation] パラジウム触媒を用いた2,3-二置換インデン誘導体の合成法2007
- Author(s)
  塚本裕一・上野達彦・根東義則
- Organizer
  第25回Combinatorial Chemistry研究会
- Place of Presentation
  東京工業大学
- Year and Date
  2007-09-27
- Data Source
  KAKENHI-PROJECT-18790003
[Presentation] Haouamine A, B および類縁体の効率的合成法の開発
- Author(s)
  塚本裕一，中村早希，土井隆行
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] アリルパラジウム中間体を求核剤として用いるアルデヒドの分子内不斉アリル化反応
- Author(s)
  川瀬歩，塚本裕一，土井隆行
- Organizer
  シンポジウムモレキュラー・キラリティー２０１４
- Place of Presentation
  仙台
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24590004
[Presentation] 二価パラジウム触媒を用いた多置換βーナフチルアミン合成法の開発
- Author(s)
  塚本裕一，池田大志，土井隆行
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2014-11-10 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590004

1. KONDO Yoshinori (90162122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. TANAKA Yoshiyuki (70333797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. DOI TAKAYUKI (90212076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 塚本佐知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsukamoto Hirokazu 塚本 裕一

TSUKAMOTO Hirokazu 塚本 裕一

Research Projects

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Co-Researchers

Catalytic synthesis of phenalenones using the double hydrogen-bond donating ability of iminium intermediatesPrincipal Investigator

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Asymmetric Hydroalkylation of Conjugate Enynes with Pronucleophiles Leading to Optically Active AllenesPrincipal Investigator

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Development of enantioselective 'anti-Wacker'-type cyclizationsPrincipal Investigator

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Middle-size cyclic peptides containing unnatural amino acids enable the control of higher cell function

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Mechanistic study on anti-Wacker-type cyclization and application to synthesis of biologically active polycyclic compoundsPrincipal Investigator

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アンチWacker型環化反応の機構解析および多環式生物活性物質合成への応用Principal Investigator

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パラジウム触媒へのアンチWacker型酸化的付加による新規環状化合物合成法の開発Principal Investigator

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イリジウム触媒を利用した芳香族C-H結合活性化によるキノリン環合成法の開発Principal Investigator

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Synthesis of bisindole derivatives using immobilized indolylmetal compounds

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[Journal Article] Scalable Total Syntheses and Structure‐Activity Relationships of Haouamine A, B, and their Derivatives as Stable Formate Salts2020

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[Journal Article] Key Factors for High Diastereo- and Enantioselectivity of Umpolung Cyclizations of Aldehyde-Containing Allylpalladium Intermediates2019

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[Journal Article] Palladium‐Catalyzed Umpolung Type‐II Cyclization of Allylic Carbonate‐Aldehydes Leading to 3‐Methylenecycloalkanol Derivatives2019

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[Journal Article] Palladium(0)－Lithium Iodide Cocatalyzed Asymmetric Hydroalkylation of Conjugated Enynes with Pronucleophiles Leading to 1,3-Disubstituted Allenes2019

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Tsukamoto Hirokazu 塚本裕一

TSUKAMOTO Hirokazu 塚本裕一