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ISE Wataru  伊勢 渉

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… Alternative Names

伊勢 渉  イセ ワタル

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Researcher Number 70323483
Other IDs
Affiliation (Current) 2020: 大阪大学, 免疫学フロンティア研究センター, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2020: 大阪大学, 免疫学フロンティア研究センター, 特任准教授(常勤)
2017 – 2018: 大阪大学, 免疫学フロンティア研究センター, 特任准教授(常勤)
2012 – 2015: 大阪大学, 免疫学フロンティア研究センター, 特任准教授
2013: 大阪大学, 免疫学フロンティア研究センター, 准教授
2001 – 2004: 東京大学, 大学院・農学生命科学研究科, 助手
Review Section/Research Field
Principal Investigator
Immunology / 食品科学・栄養科学 / Food science / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49070:Immunology-related
Except Principal Investigator
食品科学・栄養科学 / Immunology
Keywords
Principal Investigator
プラズマ細胞 / 抗体 / T細胞 / 経口免疫寛容 / 遺伝子発現 / シグナル伝達 / B細胞 / 転写因子 / lipid raft / subtraction … More / トランスジェニックマウス / 免疫記憶 / 抗体産生応答 / 記憶免疫 / 蛍光ラベル / ヘルパーT細胞 / 抗体産生 / 胚中心 / 免疫学 / 生存 / 寿命 / niche / レポーターマウス / イメージング / 長期生存 … More
Except Principal Investigator
IgE / 腸管免疫系 / T細胞 / 経口免疫寛容 / intestinal immune system / T cell / oral tolerance / Regulatory T-cells / T follicular helper / Vaccination / Antibody response / T Follicular helper / Antibody responses / 制御性T細胞 / 免疫制御 / 食品アレルギー / 小腸上皮内リンパ球(IEL) / 小腸上皮細胞 / ラフィノース / DNAマイクロアレー / プロテオーム解析 / 小腸上皮細胞(IEC) / food allergy / intraepithelial lymphocytes(IEL) / intestinal epithelial cells / raffinose / シグナル伝達 / 調節性T細胞 / 機能性食品 / アポトーシス / 樹状細胞 / 抗原提示 / 腸内細菌 / signal transduction / regulatory T cell / functional food Less
  • Research Projects

    (10 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (14 People)
  •  プラズマ細胞の長期生存と免疫調節機能を支える分子基盤の解明Principal InvestigatorOngoing

    • Principal Investigator
      伊勢 渉
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Osaka University
  •  新規レポーターマウスを用いた長寿命プラズマ細胞の可視化とその動態解析Principal InvestigatorOngoing

    • Principal Investigator
      伊勢 渉
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Osaka University
  •  高親和性プラズマ細胞の選択および生存維持を担う分子機構の解析Principal InvestigatorOngoing

    • Principal Investigator
      伊勢 渉
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Molecular mechanisms underlying the development and function of follicular helper T cellsPrincipal Investigator

    • Principal Investigator
      Ise Wataru
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Mechanisms of regulatory T-cell control of humoral immunity

    • Principal Investigator
      WING James
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Analysis of Immune Memory Dynamics by visualizing memory B cell subsetsPrincipal Investigator

    • Principal Investigator
      ISE Wataru
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  食品タンパク質の経口投与で誘導されるT細胞応答低下の分子機構の解析Principal Investigator

    • Principal Investigator
      伊勢 渉
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Food science
    • Research Institution
      The University of Tokyo
  •  Analysis of the mechanisms of discrimination, recognition and response to food proteins by the immune system

    • Principal Investigator
      HACHIMURA Satoshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      The University of Tokyo
  •  食品タンパク質の経口投与により誘導される不応答化T細胞の特性の分子生物学的解析Principal Investigator

    • Principal Investigator
      伊勢 渉
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      The University of Tokyo
  •  INDUCTION AND REGULATION OF IMMUNE AND ALLERGIC RESPONSES BY FOOD-DERIVED IMMUNE FUNCTIONAL MOLECULES

    • Principal Investigator
      KAMINOGAWA Shuichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      THE UNIVERSITY OF TOKYO

All 2018 2017 2014 2013 2005 2002 Other

All Journal Article Presentation

  • [Journal Article] T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate2018

    • Author(s)
      Ise Wataru、Fujii Kentaro、Shiroguchi Katsuyuki、Ito Ayako、Kometani Kohei、Takeda Kiyoshi、Kawakami Eiryo、Yamashita Kazuo、Suzuki Kazuhiro、Okada Takaharu、Kurosaki Tomohiro
    • Journal Title

      Immunity

      Volume: 48 Pages: 702-715

    • DOI

      10.1016/j.immuni.2018.03.027

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16KT0196, KAKENHI-PROJECT-17K08883, KAKENHI-PROJECT-18K19447, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-15H05656
  • [Journal Article] The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help2017

    • Author(s)
      Inoue T, Shinnakasu R, Ise W, Kawai C, Egawa T, Kurosaki T.
    • Journal Title

      Journal of Experimental Medicine

      Volume: 214 Pages: 1181-1198

    • DOI

      10.1084/jem.20161263

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-17K08856, KAKENHI-PROJECT-17K08882, KAKENHI-PROJECT-17K08883, KAKENHI-PROJECT-26221306
  • [Journal Article] Memory B cells contribute to rapid Bcl6 expression by memory Tfh cells.2014

    • Author(s)
      Ise W, Inoue T, McLachlan JB, Kometani K, Kubo M, Okada T, Kurosaki T
    • Journal Title

      Proc. Natl. Acad. U.S.A.

      Volume: 111 Pages: 11792-11797

    • DOI

      10.1073/pnas.1404671111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22113006, KAKENHI-PROJECT-24249058, KAKENHI-PROJECT-25293115, KAKENHI-PROJECT-26221306
  • [Journal Article] Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4.2014

    • Author(s)
      Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
    • Journal Title

      Immunity

      Volume: 41 Pages: 1013-25

    • DOI

      10.1016/j.immuni.2014.12.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25860356, KAKENHI-PROJECT-26221306
  • [Journal Article] Orally-tolerized T cells can form conjugates with APCs, but are defective in immunological synapse formation2005

    • Author(s)
      W.Ise et al.
    • Journal Title

      J.Immunol. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14360070
  • [Journal Article] Naive CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen.2002

    • Author(s)
      W.Ise, et al.
    • Journal Title

      J. Immunol. 168

      Pages: 3242-3250

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13306010
  • [Journal Article] Naive CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen.2002

    • Author(s)
      W.Ise, et al
    • Journal Title

      J.Immunol. 168

      Pages: 3242-3250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13306010
  • [Journal Article] Orally-tolerized T cells can form conjugates with APCs, but are defective in immunological synapse formation

    • Author(s)
      W.Ise et al.
    • Journal Title

      J.Immunol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360070
  • [Presentation] 液性記憶免疫応答を担うB細胞の分化とその選択機構2017

    • Author(s)
      伊勢 渉
    • Organizer
      日本食品免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K08883
  • [Presentation] The heightened T-B interaction associates with plasma-prone germinal center B cells2017

    • Author(s)
      伊勢 渉
    • Organizer
      免疫学会
    • Data Source
      KAKENHI-PROJECT-17K08883
  • [Presentation] Regulation of germinal center response by the transcription factor BATF2014

    • Author(s)
      Wataru Ise and Tomohiro Kurosaki
    • Organizer
      日本免疫学会
    • Place of Presentation
      国立京都国際会館(京都府京都市左京区)
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-25293115
  • [Presentation] Regulatory T-cells modulate T-follicular helper and germinal center formation via CTLA-42013

    • Author(s)
      Wing JB, Ise W, Kurosaki T, Sakaguchi S.
    • Organizer
      Gordon research conference T Follicular Helper Cells: Basic Discoveries and Clinical Applications
    • Place of Presentation
      The Chinese University of Hong Kong, Hong Kong, China
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Regulatory T-cells modulate T-follicular helper and germinal center formation via CTLA-42013

    • Author(s)
      Wing JB, Ise W, Kurosaki T, Sakaguchi S.
    • Organizer
      Annual meeting of Japanese society for Immunology
    • Place of Presentation
      Makuhari Messe, Chiba.
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Regulatory T-cells modulate T-follicular helper and germinal center formation via CTLA-42013

    • Author(s)
      Wing JB, Ise W, Kurosaki T, Sakaguchi S.
    • Organizer
      Kyoto T Cell Conference 2013
    • Place of Presentation
      Shiran Kaikan, Kyoto University, Kyoto
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4

    • Author(s)
      Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
    • Organizer
      The Fourth International Conference on Regulatory T Cells and Th Subsets and Clinical Application in Human Diseases
    • Place of Presentation
      Renaissance Hotel, Shanghai, China
    • Year and Date
      2014-11-01 – 2014-11-04
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4

    • Author(s)
      Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
    • Organizer
      The 13th Awaji International Forum on Infection and Immunity in Nara
    • Place of Presentation
      Nara Prefectural New Public Hall, Japan
    • Year and Date
      2014-09-23 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4

    • Author(s)
      Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
    • Organizer
      Keystone Symposium: T Cells: Regulation and Effector Function (D3)
    • Place of Presentation
      Snowbird Resort, Snowbird, Utah USA
    • Year and Date
      2015-03-29 – 2015-04-02
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Regulation of germinal center response by BATF

    • Author(s)
      Wataru Ise and Tomohiro Kurosaki
    • Organizer
      免疫記憶ワクチン国際研究会
    • Place of Presentation
      La Jolla, California, USA
    • Year and Date
      2014-08-25 – 2014-08-26
    • Data Source
      KAKENHI-PROJECT-25293115
  • [Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4

    • Author(s)
      Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
    • Organizer
      The 43rd Annual Meeting of the Japanease Society for Immunology
    • Place of Presentation
      Kyoto International Conference Center, Japan
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-25860356
  • [Presentation] Memory antibody response is regulated by antigen-specific CXCR5+ memory CD4+ T cells

    • Author(s)
      Wataru Ise and Tomohiro Kurosaki
    • Organizer
      日本免疫学会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-25293115
  • 1.  KUROSAKI Tomohiro (50178125)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  KAMINOGAWA Shuichi (50011945)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  HACHIMURA Satoshi (40238019)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  WING James (00648694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  SAKAGUCHI Shimon (30280770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 6.  TOTSUKA Mamoru (70227601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAMADA Kiyoshi (30313076)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  安達 悠 (40749016)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SHINNAKASU Ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  岡田 峰陽
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  久保 允人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  井上 毅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  川上 英良
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  鈴木 一博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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