ISE Wataru 伊勢渉

… Alternative Names

Researcher Number	70323483
Affiliation (Current)	2019: 大阪大学, 免疫学フロンティア研究センター, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2017 – 2018: 大阪大学, 免疫学フロンティア研究センター, 特任准教授(常勤) 2012 – 2015: 大阪大学, 免疫学フロンティア研究センター, 特任准教授 2013: 大阪大学, 免疫学フロンティア研究センター, 准教授 2001 – 2004: 東京大学, 大学院・農学生命科学研究科, 助手
Review Section/Research Field	Principal Investigator Immunology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / 食品科学・栄養科学 / Food science Except Principal Investigator 食品科学・栄養科学 / Immunology
Keywords	Principal Investigator 経口免疫寛容 / プラズマ細胞 / シグナル伝達 / 抗体 / 遺伝子発現 / T細胞 / B細胞 / ヘルパーT細胞 / 転写因子 / 免疫記憶 … More Except Principal Investigator IgE / 経口免疫寛容 / oral tolerance / T細胞 / 腸管免疫系 / intestinal immune system / T cell / 小腸上皮内リンパ球(IEL) / intestinal epithelial cells / Vaccination / T Follicular helper / 腸内細菌 / 免疫制御 / プロテオーム解析 / 機能性食品 / Antibody response / food allergy / 小腸上皮細胞(IEC) / T follicular helper / Regulatory T-cells / Antibody responses / 樹状細胞 / 小腸上皮細胞 / 食品アレルギー / functional food / regulatory T cell / 調節性T細胞 / シグナル伝達 / ラフィノース / DNAマイクロアレー / 抗原提示 / 制御性T細胞 / signal transduction / intraepithelial lymphocytes(IEL) / raffinose / アポトーシス Less

新規レポーターマウスを用いた長寿命プラズマ細胞の可視化とその動態解析Principal InvestigatorOngoing
- Principal Investigator
  
  伊勢渉
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University
高親和性プラズマ細胞の選択および生存維持を担う分子機構の解析Principal InvestigatorOngoing
- Principal Investigator
  
  伊勢渉
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Molecular mechanisms underlying the development and function of follicular helper T cellsPrincipal Investigator
- Principal Investigator
  
  Ise Wataru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Mechanisms of regulatory T-cell control of humoral immunity
- Principal Investigator
  
  WING James
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Analysis of Immune Memory Dynamics by visualizing memory B cell subsetsPrincipal Investigator
- Principal Investigator
  
  ISE Wataru
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Osaka University
食品タンパク質の経口投与で誘導されるT細胞応答低下の分子機構の解析Principal Investigator
- Principal Investigator
  
  伊勢渉
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Analysis of the mechanisms of discrimination, recognition and response to food proteins by the immune system
- Principal Investigator
  
  HACHIMURA Satoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  The University of Tokyo
食品タンパク質の経口投与により誘導される不応答化T細胞の特性の分子生物学的解析Principal Investigator
- Principal Investigator
  
  伊勢渉
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  The University of Tokyo
INDUCTION AND REGULATION OF IMMUNE AND ALLERGIC RESPONSES BY FOOD-DERIVED IMMUNE FUNCTIONAL MOLECULES
- Principal Investigator
  
  KAMINOGAWA Shuichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  THE UNIVERSITY OF TOKYO

All 2018 2017 2014 2013 2005 2002 Other

All Journal Article Presentation

[Journal Article] T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate2018
- Author(s)
  Ise Wataru、Fujii Kentaro、Shiroguchi Katsuyuki、Ito Ayako、Kometani Kohei、Takeda Kiyoshi、Kawakami Eiryo、Yamashita Kazuo、Suzuki Kazuhiro、Okada Takaharu、Kurosaki Tomohiro
- Journal Title
  
  Immunity
  
  Volume: 48 Pages: 702-715
- DOI
  10.1016/j.immuni.2018.03.027
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PROJECT-17K08883
[Journal Article] The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help2017
- Author(s)
  Inoue T, Shinnakasu R, Ise W, Kawai C, Egawa T, Kurosaki T.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 214 Pages: 1181-1198
- DOI
  10.1084/jem.20161263
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-17K08856, KAKENHI-PROJECT-17K08882, KAKENHI-PROJECT-17K08883, KAKENHI-PROJECT-26221306
[Journal Article] Memory B cells contribute to rapid Bcl6 expression by memory Tfh cells.2014
- Author(s)
  Ise W, Inoue T, McLachlan JB, Kometani K, Kubo M, Okada T, Kurosaki T
- Journal Title
  
  Proc. Natl. Acad. U.S.A.
  
  Volume: 111 Pages: 11792-11797
- DOI
  10.1073/pnas.1404671111
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22113006, KAKENHI-PROJECT-24249058, KAKENHI-PROJECT-25293115, KAKENHI-PROJECT-26221306
[Journal Article] Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4.2014
- Author(s)
  Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
- Journal Title
  
  Immunity
  
  Volume: 41 Pages: 1013-25
- DOI
  10.1016/j.immuni.2014.12.006
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860356, KAKENHI-PROJECT-26221306
[Journal Article] Orally-tolerized T cells can form conjugates with APCs, but are defective in immunological synapse formation2005
- Author(s)
  W.Ise et al.
- Journal Title
  
  J.Immunol. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14360070
[Journal Article] Naive CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen.2002
- Author(s)
  W.Ise, et al.
- Journal Title
  
  J. Immunol. 168
  
  Pages: 3242-3250
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13306010
[Journal Article] Naive CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen.2002
- Author(s)
  W.Ise, et al
- Journal Title
  
  J.Immunol. 168
  
  Pages: 3242-3250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13306010
[Journal Article] Orally-tolerized T cells can form conjugates with APCs, but are defective in immunological synapse formation
- Author(s)
  W.Ise et al.
- Journal Title
  
  J.Immunol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14360070
[Presentation] 液性記憶免疫応答を担うB細胞の分化とその選択機構2017
- Author(s)
  伊勢　渉
- Organizer
  日本食品免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08883
[Presentation] The heightened T-B interaction associates with plasma-prone germinal center B cells2017
- Author(s)
  伊勢　渉
- Organizer
  免疫学会
- Data Source
  KAKENHI-PROJECT-17K08883
[Presentation] Regulation of germinal center response by the transcription factor BATF2014
- Author(s)
  Wataru Ise and Tomohiro Kurosaki
- Organizer
  日本免疫学会
- Place of Presentation
  国立京都国際会館（京都府京都市左京区）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-25293115
[Presentation] Regulatory T-cells modulate T-follicular helper and germinal center formation via CTLA-42013
- Author(s)
  Wing JB, Ise W, Kurosaki T, Sakaguchi S.
- Organizer
  Annual meeting of Japanese society for Immunology
- Place of Presentation
  Makuhari Messe, Chiba.
- Data Source
  KAKENHI-PROJECT-25860356
[Presentation] Regulatory T-cells modulate T-follicular helper and germinal center formation via CTLA-42013
- Author(s)
  Wing JB, Ise W, Kurosaki T, Sakaguchi S.
- Organizer
  Kyoto T Cell Conference 2013
- Place of Presentation
  Shiran Kaikan, Kyoto University, Kyoto
- Data Source
  KAKENHI-PROJECT-25860356
[Presentation] Regulatory T-cells modulate T-follicular helper and germinal center formation via CTLA-42013
- Author(s)
  Wing JB, Ise W, Kurosaki T, Sakaguchi S.
- Organizer
  Gordon research conference T Follicular Helper Cells: Basic Discoveries and Clinical Applications
- Place of Presentation
  The Chinese University of Hong Kong, Hong Kong, China
- Data Source
  KAKENHI-PROJECT-25860356
[Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4
- Author(s)
  Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
- Organizer
  Keystone Symposium: T Cells: Regulation and Effector Function (D3)
- Place of Presentation
  Snowbird Resort, Snowbird, Utah USA
- Year and Date
  2015-03-29 – 2015-04-02
- Data Source
  KAKENHI-PROJECT-25860356
[Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4
- Author(s)
  Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
- Organizer
  The 43rd Annual Meeting of the Japanease Society for Immunology
- Place of Presentation
  Kyoto International Conference Center, Japan
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860356
[Presentation] Memory antibody response is regulated by antigen-specific CXCR5+ memory CD4+ T cells
- Author(s)
  Wataru Ise and Tomohiro Kurosaki
- Organizer
  日本免疫学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25293115
[Presentation] Regulation of germinal center response by BATF
- Author(s)
  Wataru Ise and Tomohiro Kurosaki
- Organizer
  免疫記憶ワクチン国際研究会
- Place of Presentation
  La Jolla, California, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PROJECT-25293115
[Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4
- Author(s)
  Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
- Organizer
  The 13th Awaji International Forum on Infection and Immunity in Nara
- Place of Presentation
  Nara Prefectural New Public Hall, Japan
- Year and Date
  2014-09-23 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25860356
[Presentation] Regulatory T-cells control antigen-specific Tfh expansion and humoral immune responses via CTLA-4
- Author(s)
  Wing, JB. Ise, W. Kurosaki, T. Sakaguchi, S.
- Organizer
  The Fourth International Conference on Regulatory T Cells and Th Subsets and Clinical Application in Human Diseases
- Place of Presentation
  Renaissance Hotel, Shanghai, China
- Year and Date
  2014-11-01 – 2014-11-04
- Data Source
  KAKENHI-PROJECT-25860356

1. KUROSAKI Tomohiro (50178125)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. KAMINOGAWA Shuichi (50011945)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HACHIMURA Satoshi (40238019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WING James (00648694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. SAKAGUCHI Shimon (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. TOTSUKA Mamoru (70227601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMADA Kiyoshi (30313076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 安達悠 (40749016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHINNAKASU Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 川上英良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 井上毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 岡田峰陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 久保允人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISE Wataru 伊勢 渉

伊勢 渉 イセ ワタル

Research Projects

Research Products

Co-Researchers

新規レポーターマウスを用いた長寿命プラズマ細胞の可視化とその動態解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高親和性プラズマ細胞の選択および生存維持を担う分子機構の解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms underlying the development and function of follicular helper T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of regulatory T-cell control of humoral immunity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Immune Memory Dynamics by visualizing memory B cell subsetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

食品タンパク質の経口投与で誘導されるT細胞応答低下の分子機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanisms of discrimination, recognition and response to food proteins by the immune system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

食品タンパク質の経口投与により誘導される不応答化T細胞の特性の分子生物学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

INDUCTION AND REGULATION OF IMMUNE AND ALLERGIC RESPONSES BY FOOD-DERIVED IMMUNE FUNCTIONAL MOLECULES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Memory B cells contribute to rapid Bcl6 expression by memory Tfh cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Orally-tolerized T cells can form conjugates with APCs, but are defective in immunological synapse formation2005

ISE Wataru 伊勢渉

伊勢渉イセワタル