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Yokokawa Akitomo  横川 彰朋

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YOKOKAWA Akitomo  横川 彰朋

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Researcher Number 70328558
Other IDs
Affiliation (Current) 2025: 東京薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2025: 東京薬科大学, 薬学部, 講師
2012 – 2014: 東京薬科大学, 薬学部, 助教
2004 – 2006: 東京薬科大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Except Principal Investigator
Medical pharmacy
Keywords
Principal Investigator
11β-HSD / 酵素活性 / 本態性高血圧 / 腎疾患 / 11β-HSD2 / コルチゾン / コルチゾール
Except Principal Investigator
GC-MS-SIM / hypertension / renal disease … More / cortisol ratio / urinary cortisone / 11β-activity / stable isotope methodology / cortisone / cortisol / 11β-HSD2酵素活性評価 / 安定同位体標識 / 速度論的解析 / 体内動態 / グリチルリチン酸 / 安定同位体標識体 / 11β-HSD2の酵素活性 / 腎疾患患者 / F比 / 尿中E / GC-MS分析 / コルチゾン / 11β-HSD2酵素活性 / コルチゾール Less
  • Research Projects

    (3 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (5 People)
  •  個別化薬物治療を目指した内因性物質による新規CYP1A2活性評価法の開発Principal Investigator

    • Principal Investigator
      横川 彰朋
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  The relationship between 11beta-hydroxysteroid dehydrogenase 2 enzyme activity and blood pressure in patients with renal diseasePrincipal Investigator

    • Principal Investigator
      YOKOKAWA Akitomo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Evaluation of in vivo enzymatic activity of cortisol metabolism associated with hypertension

    • Principal Investigator
      KASUYA Yasuji
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Sciences

All 2014 2013 2012 2005

All Journal Article Presentation

  • [Journal Article] Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans2013

    • Author(s)
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii, and Takashi Furuta
    • Journal Title

      Drug Metab. Dispos.

      Volume: 41 Issue: 2 Pages: 475-479

    • DOI

      10.1124/dmd.112.048561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790172
  • [Journal Article] The effect of water loading on the urinary ratio of cortisone to cortisol in healthy subjects and a new approach to the evaluation of the ratio as an index for in vivo human 11β-hydroxysteroid dehydrogenase 2 activity2012

    • Author(s)
      Akitomo Yokokawa, Toru Takasaka, Hiromi Shibasaki, Yasuji Kasuya, Soko Kawashima, Akira Yamada, and Takashi Furuta
    • Journal Title

      Steroids

      Volume: 77 Issue: 12 Pages: 1291-1297

    • DOI

      10.1016/j.steroids.2012.07.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790172
  • [Journal Article] Use of 11 a-deuterium labeled cortisol as a tracer for assessing reduced 11 β-HSD2 activity in vivo following glycyrrhetinic acid ingestion in a human subject.2005

    • Author(s)
      Y.Kasuya, A.Yokokawa, S.Takashima, H.Shibasaki, T.Futruta
    • Journal Title

      Steroids 70-2

      Pages: 117-125

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590126
  • [Journal Article] Validation of the plasma half-life of 11α-deuterium cortisol as a sensitive indexr for the analysis of 11β-HSD2 activity in vivo.2005

    • Author(s)
      Kasuya Y, Yokokawa A, Hamura K, Shibasaki H, Furuta T
    • Journal Title

      Steroids 70・12

      Pages: 811-816

    • Data Source
      KAKENHI-PROJECT-16590126
  • [Journal Article] Validation of the plasma half-life of 1la-deuterium cortisol as a sensitive index for the analysis of human 11β-HSD2 activity in vivo.2005

    • Author(s)
      Y.Kasuya, A.Yokokawa, K.Hamura, H.Shibasaki, T.Futruta
    • Journal Title

      Steroids 70-12

      Pages: 811-816

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590126
  • [Journal Article] Use of 11α-deuterium labeled cortisol as a tracer for assessing reduced 11β-HSD2 activity in vivo following glycyrrhetinic acid ingestion in a human subject2005

    • Author(s)
      Kasuya Y, Yokokawa A, Takashima S, Furuta T, Shibasaki H
    • Journal Title

      Steroids 70・2

      Pages: 117-125

    • Data Source
      KAKENHI-PROJECT-16590126
  • [Presentation] LC-MS/MSによる尿中6α-および6β-ヒドロキシコルチゾールの安定同位体質量分析法の開発2014

    • Author(s)
      横川彰朋,青野智恵美,柴崎浩美,細田香織,石井和夫,古田隆
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24790172
  • [Presentation] ヒトin vivo における11β-HSD2 活性の日内・日間変動に関する研究2013

    • Author(s)
      横川彰朋,柴崎浩美,細田香織,石井和夫,古田隆
    • Organizer
      第53 回日本臨床化学会年次集会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-24790172
  • [Presentation] Individual variability of cortisone/cortisol ratio correlated to the cortisol concentration in human urine as a new index for phenotyping in vivo 11β-hydroxysteroid dehydrogenase 2 activity2012

    • Author(s)
      Akitomo Yokokawa, Hiromi Shibasaki, Takashi Furuta
    • Organizer
      6th European Congress of Pharmacology
    • Place of Presentation
      Granada, Spain
    • Data Source
      KAKENHI-PROJECT-24790172
  • [Presentation] 尿量増加による尿中cortisone/cortisol比の変動とヒトin vivo 11β-HSD2酵素活性評価法2012

    • Author(s)
      横川彰朋,柴崎浩美,古田隆
    • Organizer
      第52 回日本臨床化学会年次集会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-24790172
  • 1.  FURUTA Takashi (70120152)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  SHIBASAKI Hiromi (20206121)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  KASUYA Yasuji (90096686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  山田 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  川嶋 聡子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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