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Okimoto Nobukazu  沖本 信和

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OKIMOTO Nobukazu  沖本 信和

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Researcher Number 70330991
Other IDs
Affiliation (Current) 2025: 産業医科大学, 医学部, 非常勤医師
Affiliation (based on the past Project Information) *help 2009: 産業医科大学, 医学部, 助手
2006 – 2007: 産業医科大学, 医学部, 非常勤医師
2001 – 2005: 産業医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Orthopaedic surgery
Except Principal Investigator
Orthopaedic surgery / Orthopaedic surgery
Keywords
Principal Investigator
骨組織形態計測 / 骨髄細胞 / 自発運動負荷モデル / マウス / climbming / osteoblast / voluntary exercise / alkaline phosphatase / mineralized nodule / cortical bone … More / bone formation rate / osteoclast / エストロゲン / 皮質骨構造 / 海面骨構造 / 破骨細胞 / 骨芽細胞 … More
Except Principal Investigator
破骨細胞 / 骨形成 / 骨芽細胞 / LDL / Wnt / LRP5 / loading / 骨髄細胞 / 海綿骨 / 非荷重 / CFU-f / 荷重 / 骨量 / 骨吸収 / オステオカルシン / OXYTOCIN / VASOPRESSIN / 2-BUTEN-4-OLIDE / GENE EXPRESSION / GALANIN-LIKE PEPTIDE / HYPOTHALAMUS / NEUROPEPTIDE / RHEUMATOID ARTHRITIS / パゾプレッシン / オキシトシン / バゾプレッシン / 2-buten-4-olide / 遺伝子発現 / ガラニン様ペプチド / 視床下部 / 神経ペプチド / 関節リウマチ / PTH / bone marrow cell / osteoblast / bone / Mac-1 / RANKL / 不動 / 過酸化脂質 / 高脂質食 / アポリポプロテインE / p53 / アポトーシス / 酸化LDL / 脂質 / 脂肪細胞 / 副甲状腺ホルモン / 低リポ蛋白受容体 / 骨 / nitric oxide / bone resorption / bone formation / bone strength / bone volume / exercise / マウス / 尾部懸垂 / NO / iNOS / クライミング / 慢性荷重 / 繊維性結節形成能 / ミネラル沈着結節形成能 / 2型コラーゲン誘発関節炎 / 炎症 / c-fos / cyclor-oxygenase-2 / 再荷重 / 一酸化窒素 / 骨強度 / 運動 / 代謝回転 / flt-1 / 髄内仮骨 / 血管形成 / HIF-1α / 骨・骨髄損傷 / HIF-1 / HIF / BMP-2 / PECAM-1 / VEGF / 血管 / ビタミンA / シグナル伝達 / 骨髄損傷 / 関節 / 脳 / CIAマウス / urocortin Less
  • Research Projects

    (7 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (7 People)
  •  Bone and vascular signals during the repair process after bone and bone marrow injury

    • Principal Investigator
      SAKAI Akinori
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The role of signal of low-density lipoprotein-related protein receptor in bone after intermittent skeletal loading

    • Principal Investigator
      NAKAMURA Toshitaka
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Clarification of new brain peptide's pathophysiologic role and molecular mechanism in arthritic animal model.

    • Principal Investigator
      OHNISHI Hideo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health
  •  Investigation for bone mass and trabecular bone turnover through transient regulation of marrow osteogenic and osteoclastogenic potentials follow by climbming exercisePrincipal Investigator

    • Principal Investigator
      OKIMOTO Nobukazu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health
  •  マウス運動負荷モデルでの、骨動態変化と骨髄細胞分化異常の分子細胞メカニズムの解明Principal Investigator

    • Principal Investigator
      沖本 信和
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  コラーゲン誘発関節炎マウスにおける脳内urocortin発現と関節炎発症との関連

    • Principal Investigator
      ONISHI HIDEO
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The regulation of cell proliferation and differentiation of bone cells after the change of gravity loading

    • Principal Investigator
      NAKAMURA Toshitaka
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Occupational and Environmental Health

All 2008 2006 2005 2004

All Journal Article

  • [Journal Article] Climbing exercise enhances osteoblast differentiation and inhibits adipogenic differentiation with high expression of PTH/PTHrP receptor in bone marrow cells.2008

    • Author(s)
      Menuki K, Mori T, Sakai A, Sakuma M, Okimoto N, Shimizu Y, Kunugita N, Nakamura T
    • Journal Title

      Bone 43巻3号

      Pages: 613-620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390422
  • [Journal Article] THE SHORT CHAIN SUGAR ACID, 2-BUTEN-4-OLIDE, ACTIVATES OXYTOCIN-SECRETING NEURONS BUT NOT ARGININE VASOPRESSIN-SECRETING NEURONS IN THE HYPOTHALAMUS OF RATS2006

    • Author(s)
      KAWASAKI M, YAMAGA C, ONAKA T, SAITO J, MERA T, HASHIMOTO T, FUJAIHARA H, OKIMOTO N, OHNISHI H, NAKAMURA T, UETA Y.
    • Journal Title

      BRAIN RESEARCH 1086(1)

      Pages: 133-141

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats2006

    • Author(s)
      Kawasaki M, Yamaga C, Onaka T, Saito J, Mera T, Hashimoto T, Fujaihara H, Okimoto N, Ohnishi H, Nakamura T, Ueta Y
    • Journal Title

      Brain Research 1086(1)

      Pages: 133-141

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] INDUCTION OF GALANIN-LIKE PEPTIDE GENE EXPRESSION IN THE ARCUATE NUCLEUS OF THE RAT AFTER ACUTE BUT NOT CHRONIC INFLAMMATORY STRESS.2005

    • Author(s)
      SAITO, J., OZAKI, Y., KAWASAKI, M., OHNISHI, H., OKIMOTO, N., NAKAMURA, T., UETA, Y.
    • Journal Title

      MOLECULAR BRAIN RESEARCH 133(2)

      Pages: 233-241

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] Induction of galanin-like peptide gene expression in the arcuate nucleus of the rat after acute but not chronic inflammatory stress.2005

    • Author(s)
      Saito, J., Ozaki, Y., Kawasaki, M., Ohnishi, H., Okimoto, N., Nakamura, T., Ueta, Y.
    • Journal Title

      Molecular Brain Research 133(2)

      Pages: 233-241

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus.2005

    • Author(s)
      Kawasaki M, Okimoto N, Ohnishi H, Nakamura T, Ueta Y.
    • Journal Title

      J Neuroendocrinol In press

    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus2005

    • Author(s)
      Kawasaki M, Yamaguchi K, Saito J, Ozaki Y, Mera T, Hashimoto T, Fujaihara H, Okimoto N, Ohnishi H, Nakamura T, Ueta Y
    • Journal Title

      Journal of Neuroendocrinology 17(4)

      Pages: 227-237

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] Induction of galanin-like peptide gene expression in the arcuate nucleus of the rat2005

    • Author(s)
      Saito J, Ohnishi H, Okimoto N, Nakamura T, Ueta Y.
    • Journal Title

      Brain Res Mol Brain Res. 18;133(2)

      Pages: 233-241

    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] EXPRESSION OF IMMEDIATE EARLY GENES AND VASOPRESSIN HETERONUCLEAR RNA IN THE PARAVENTRICULAR AND SUPRAOPTIC NUCLEI OF RATS AFTER ACUTE OSMOTIC STIMULUS2005

    • Author(s)
      KAWASAKI M, YAMAGUCHI K, SAITO J, OZAKI Y, MERA T, HASHIMOTO T, FUJAIHARA H, OKIMOTO N, OHNISHI H, NAKAMURA T, UETA Y.
    • Journal Title

      JOURNAL OF NEUROENDOCRINOLOGY 17(4)

      Pages: 227-237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] GALANIN-LIKE PEPTIDE GENE EXPRESSION IN THE HYPOTHALAMUS AND POSTERIOR PITUITARY OF THE OBESE FA/FA RAT.2004

    • Author(s)
      SAITO, J., OZAKI, Y., KAWASAKI, M., OHNISHI, H., OKIMOTO, N., NAKAMURA, T., UETA, Y.
    • Journal Title

      PEPTIDES 25(6)

      Pages: 967-974

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] Galanin-like peptide gene expression in the hypothalamus and posterior pituitary of the obese fa/fa rat.2004

    • Author(s)
      Saito J, Ohnishi H, Okimoto N, Nakamura T, Ueta Y.
    • Journal Title

      Peptides 25(6)

      Pages: 967-974

    • Data Source
      KAKENHI-PROJECT-16591518
  • [Journal Article] Galanin-like peptide gene expression in the hypothalamus and posterior pituitary of the obese fa/fa rat.2004

    • Author(s)
      Saito, J., Ozaki, Y., Kawasaki, M., Ohnishi, H., Okimoto, N., Nakamura, T., Ueta, Y.
    • Journal Title

      Peptides 25(6)

      Pages: 967-974

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591518
  • 1.  NAKAMURA Toshitaka (50082235)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 12 results
  • 2.  SAKAI Akinori (90248576)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  ONISHI HIDEO (20279342)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 4.  UETA Yoichi (10232745)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 5.  内田 宗志 (60330990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  池田 聡 (80341501)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  岡崎 龍史 (50309960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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