Okimoto Nobukazu 沖本信和

… Alternative Names

OKIMOTO Nobukazu 沖本信和

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Researcher Number	70330991
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 非常勤医師
Affiliation (based on the past Project Information) *help	2009: 産業医科大学, 医学部, 助手 2006 – 2007: 産業医科大学, 医学部, 非常勤医師 2001 – 2005: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery
Keywords	Principal Investigator 骨組織形態計測 / 骨髄細胞 / 自発運動負荷モデル / マウス / climbming / osteoblast / voluntary exercise / alkaline phosphatase / mineralized nodule / cortical bone … More / bone formation rate / osteoclast / エストロゲン / 皮質骨構造 / 海面骨構造 / 破骨細胞 / 骨芽細胞 … More Except Principal Investigator 破骨細胞 / 骨形成 / 骨芽細胞 / LDL / Wnt / LRP5 / loading / 骨髄細胞 / 海綿骨 / 非荷重 / CFU-f / 荷重 / 骨量 / 骨吸収 / オステオカルシン / OXYTOCIN / VASOPRESSIN / 2-BUTEN-4-OLIDE / GENE EXPRESSION / GALANIN-LIKE PEPTIDE / HYPOTHALAMUS / NEUROPEPTIDE / RHEUMATOID ARTHRITIS / パゾプレッシン / オキシトシン / バゾプレッシン / 2-buten-4-olide / 遺伝子発現 / ガラニン様ペプチド / 視床下部 / 神経ペプチド / 関節リウマチ / PTH / bone marrow cell / osteoblast / bone / Mac-1 / RANKL / 不動 / 過酸化脂質 / 高脂質食 / アポリポプロテインE / p53 / アポトーシス / 酸化LDL / 脂質 / 脂肪細胞 / 副甲状腺ホルモン / 低リポ蛋白受容体 / 骨 / nitric oxide / bone resorption / bone formation / bone strength / bone volume / exercise / マウス / 尾部懸垂 / NO / iNOS / クライミング / 慢性荷重 / 繊維性結節形成能 / ミネラル沈着結節形成能 / 2型コラーゲン誘発関節炎 / 炎症 / c-fos / cyclor-oxygenase-2 / 再荷重 / 一酸化窒素 / 骨強度 / 運動 / 代謝回転 / flt-1 / 髄内仮骨 / 血管形成 / HIF-1α / 骨・骨髄損傷 / HIF-1 / HIF / BMP-2 / PECAM-1 / VEGF / 血管 / ビタミンA / シグナル伝達 / 骨髄損傷 / 関節 / 脳 / CIAマウス / urocortin Less

Bone and vascular signals during the repair process after bone and bone marrow injury
- Principal Investigator
  
  SAKAI Akinori
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
The role of signal of low-density lipoprotein-related protein receptor in bone after intermittent skeletal loading
- Principal Investigator
  
  NAKAMURA Toshitaka
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Clarification of new brain peptide's pathophysiologic role and molecular mechanism in arthritic animal model.
- Principal Investigator
  
  OHNISHI Hideo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health
Investigation for bone mass and trabecular bone turnover through transient regulation of marrow osteogenic and osteoclastogenic potentials follow by climbming exercisePrincipal Investigator
- Principal Investigator
  
  OKIMOTO Nobukazu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health
マウス運動負荷モデルでの、骨動態変化と骨髄細胞分化異常の分子細胞メカニズムの解明Principal Investigator
- Principal Investigator
  
  沖本信和
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
コラーゲン誘発関節炎マウスにおける脳内urocortin発現と関節炎発症との関連
- Principal Investigator
  
  ONISHI HIDEO
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
The regulation of cell proliferation and differentiation of bone cells after the change of gravity loading
- Principal Investigator
  
  NAKAMURA Toshitaka
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health

All 2008 2006 2005 2004

All Journal Article

[Journal Article] Climbing exercise enhances osteoblast differentiation and inhibits adipogenic differentiation with high expression of PTH/PTHrP receptor in bone marrow cells.2008
- Author(s)
  Menuki K, Mori T, Sakai A, Sakuma M, Okimoto N, Shimizu Y, Kunugita N, Nakamura T
- Journal Title
  
  Bone 43巻3号
  
  Pages: 613-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390422
[Journal Article] THE SHORT CHAIN SUGAR ACID, 2-BUTEN-4-OLIDE, ACTIVATES OXYTOCIN-SECRETING NEURONS BUT NOT ARGININE VASOPRESSIN-SECRETING NEURONS IN THE HYPOTHALAMUS OF RATS2006
- Author(s)
  KAWASAKI M, YAMAGA C, ONAKA T, SAITO J, MERA T, HASHIMOTO T, FUJAIHARA H, OKIMOTO N, OHNISHI H, NAKAMURA T, UETA Y.
- Journal Title
  
  BRAIN RESEARCH 1086(1)
  
  Pages: 133-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats2006
- Author(s)
  Kawasaki M, Yamaga C, Onaka T, Saito J, Mera T, Hashimoto T, Fujaihara H, Okimoto N, Ohnishi H, Nakamura T, Ueta Y
- Journal Title
  
  Brain Research 1086(1)
  
  Pages: 133-141
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] INDUCTION OF GALANIN-LIKE PEPTIDE GENE EXPRESSION IN THE ARCUATE NUCLEUS OF THE RAT AFTER ACUTE BUT NOT CHRONIC INFLAMMATORY STRESS.2005
- Author(s)
  SAITO, J., OZAKI, Y., KAWASAKI, M., OHNISHI, H., OKIMOTO, N., NAKAMURA, T., UETA, Y.
- Journal Title
  
  MOLECULAR BRAIN RESEARCH 133(2)
  
  Pages: 233-241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] Induction of galanin-like peptide gene expression in the arcuate nucleus of the rat after acute but not chronic inflammatory stress.2005
- Author(s)
  Saito, J., Ozaki, Y., Kawasaki, M., Ohnishi, H., Okimoto, N., Nakamura, T., Ueta, Y.
- Journal Title
  
  Molecular Brain Research 133(2)
  
  Pages: 233-241
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus.2005
- Author(s)
  Kawasaki M, Okimoto N, Ohnishi H, Nakamura T, Ueta Y.
- Journal Title
  
  J Neuroendocrinol In press
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus2005
- Author(s)
  Kawasaki M, Yamaguchi K, Saito J, Ozaki Y, Mera T, Hashimoto T, Fujaihara H, Okimoto N, Ohnishi H, Nakamura T, Ueta Y
- Journal Title
  
  Journal of Neuroendocrinology 17(4)
  
  Pages: 227-237
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] Induction of galanin-like peptide gene expression in the arcuate nucleus of the rat2005
- Author(s)
  Saito J, Ohnishi H, Okimoto N, Nakamura T, Ueta Y.
- Journal Title
  
  Brain Res Mol Brain Res. 18;133(2)
  
  Pages: 233-241
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] EXPRESSION OF IMMEDIATE EARLY GENES AND VASOPRESSIN HETERONUCLEAR RNA IN THE PARAVENTRICULAR AND SUPRAOPTIC NUCLEI OF RATS AFTER ACUTE OSMOTIC STIMULUS2005
- Author(s)
  KAWASAKI M, YAMAGUCHI K, SAITO J, OZAKI Y, MERA T, HASHIMOTO T, FUJAIHARA H, OKIMOTO N, OHNISHI H, NAKAMURA T, UETA Y.
- Journal Title
  
  JOURNAL OF NEUROENDOCRINOLOGY 17(4)
  
  Pages: 227-237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] GALANIN-LIKE PEPTIDE GENE EXPRESSION IN THE HYPOTHALAMUS AND POSTERIOR PITUITARY OF THE OBESE FA/FA RAT.2004
- Author(s)
  SAITO, J., OZAKI, Y., KAWASAKI, M., OHNISHI, H., OKIMOTO, N., NAKAMURA, T., UETA, Y.
- Journal Title
  
  PEPTIDES 25(6)
  
  Pages: 967-974
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] Galanin-like peptide gene expression in the hypothalamus and posterior pituitary of the obese fa/fa rat.2004
- Author(s)
  Saito J, Ohnishi H, Okimoto N, Nakamura T, Ueta Y.
- Journal Title
  
  Peptides 25(6)
  
  Pages: 967-974
- Data Source
  KAKENHI-PROJECT-16591518
[Journal Article] Galanin-like peptide gene expression in the hypothalamus and posterior pituitary of the obese fa/fa rat.2004
- Author(s)
  Saito, J., Ozaki, Y., Kawasaki, M., Ohnishi, H., Okimoto, N., Nakamura, T., Ueta, Y.
- Journal Title
  
  Peptides 25(6)
  
  Pages: 967-974
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591518

1. NAKAMURA Toshitaka (50082235)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. SAKAI Akinori (90248576)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. ONISHI HIDEO (20279342)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
4. UETA Yoichi (10232745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. 内田宗志 (60330990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 池田聡 (80341501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡崎龍史 (50309960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Okimoto Nobukazu 沖本 信和

OKIMOTO Nobukazu 沖本 信和

Research Projects

Research Products

Co-Researchers

Bone and vascular signals during the repair process after bone and bone marrow injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of signal of low-density lipoprotein-related protein receptor in bone after intermittent skeletal loading

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of new brain peptide's pathophysiologic role and molecular mechanism in arthritic animal model.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for bone mass and trabecular bone turnover through transient regulation of marrow osteogenic and osteoclastogenic potentials follow by climbming exercisePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マウス運動負荷モデルでの、骨動態変化と骨髄細胞分化異常の分子細胞メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

コラーゲン誘発関節炎マウスにおける脳内urocortin発現と関節炎発症との関連

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulation of cell proliferation and differentiation of bone cells after the change of gravity loading

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Climbing exercise enhances osteoblast differentiation and inhibits adipogenic differentiation with high expression of PTH/PTHrP receptor in bone marrow cells.2008

Author(s)

Journal Title

Data Source

[Journal Article] THE SHORT CHAIN SUGAR ACID, 2-BUTEN-4-OLIDE, ACTIVATES OXYTOCIN-SECRETING NEURONS BUT NOT ARGININE VASOPRESSIN-SECRETING NEURONS IN THE HYPOTHALAMUS OF RATS2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] INDUCTION OF GALANIN-LIKE PEPTIDE GENE EXPRESSION IN THE ARCUATE NUCLEUS OF THE RAT AFTER ACUTE BUT NOT CHRONIC INFLAMMATORY STRESS.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Induction of galanin-like peptide gene expression in the arcuate nucleus of the rat after acute but not chronic inflammatory stress.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus.2005

Author(s)

Journal Title

Data Source

[Journal Article] Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus2005

Author(s)

Journal Title

Description

Data Source

Okimoto Nobukazu 沖本信和

OKIMOTO Nobukazu 沖本信和