Yanagihara Kazuhiro 柳原一広

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YANAGIHARA Kazuhiro 柳原一広

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Researcher Number	70332731
Affiliation (Current)	2025: 株式会社関西メディカルネット(関西電力医学研究所), 臨床腫瘍研究部, 部長
Affiliation (based on the past Project Information) *help	2012: 京都大学, 医学系研究科, 准教授 2011: 京都大学, 医学研究科, 准教授 2009: 京都大学, 大学院・医学系研究科, 准教授 2007 – 2008: 京都大学, 医学(系)研究科(研究院), 准教授 2007 – 2008: Kyoto University, 医学研究科, 准教授 2002 – 2003: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Medical sociology Except Principal Investigator Thoracic surgery / Medical pharmacy / Respiratory organ internal medicine / General internal medicine (including Psychosomatic medicine) / Applied pharmacology
Keywords	Principal Investigator TAPS / CTCAE / RECIST / ガイドライン / 臨床腫瘍学 / がん診療 / 医学教育学 Except Principal Investigator A3G3F0 / RECK / 非小細胞肺癌 … More / 化学療法 / がん / malignant tumors / sugar chains / lung cancer / フコース / 予後因子 / 血管新生 / 転移 / 糖蛋白 / 糖鎖 / 肺癌 / 分子標的抗がん剤 / 薬剤反応性 / 癌 / 薬学 / P糖蛋白質 / 腫瘍循環 / 腫瘍微小循環 / 腫瘍内低酸素 / 多施設無作為化臨床試験 / 生存シグナル / 血管内皮成長因子 / P糖蛋白 / 多施設第II相proof of concept臨床試験 / ニトログリセリン / 一酸化窒素 / 腫瘍内微小循環 / 低酸素誘導因子 / 低酸素誘導性抗がん薬耐性化機序 / 多施設 / うつ / 不安 / QOL / 支援 / 外来 / 多施設比較 / ニード / 薬理遺伝学 / 臨床薬理学 Less

Construction of administration algorithm of novel oral molecular-targeted anti-cancer drugs based on the clarificationof interindividual differences of pharmacokinetics and pharmacodynamics
- Principal Investigator
  
  TERADA Tomohiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Shiga University of Medical Science
Educational system of oncologyPrincipal Investigator
- Principal Investigator
  
  YANAGIHARA Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Kyoto University
Standardization of tailor-made chemotherapy based on pharmacokinetics and pharmacogenomics
- Principal Investigator
  
  ISHIGURO Hiroshi
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Study of Patients' Needs who are receiving chemotherapy at ambulatory settings: multi-institutional study
- Principal Investigator
  
  WADA Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Saitama Medical University
The basic and clinical research regarding development of combinationalchemotherapy with nitric oxide donating drugs for non-small cell lung cancer
- Principal Investigator
  
  YASUDA Hiroyasu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
  Kyoto University
A Systemic Analysis of Sugar Chains in Non-Small Lung Cancer
- Principal Investigator
  
  TANAKA Fumihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  KYOTO UNIVERSITY

All 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] がん化学療法と患者ケア改訂第2版2007
- Author(s)
  福島雅典、柳原一広、石黒洋、他
- Publisher
  医学芸術社
- Data Source
  KAKENHI-PROJECT-19590533
[Journal Article] Degree of freezing does not affect efficacy of frozen gloves for prevention of do cetaxel-induced nail toxicity in breast cancer patients2011
- Author(s)
  Ishiguro H(1番目), Yano I, Yanagihara K, et al
- Journal Title
  
  Support Care Cancer
  
  Volume: (in press) Issue: 9 Pages: 2017-2024
- DOI
  10.1007/s00520-011-1308-4
- NAID
  120004873705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590533, KAKENHI-PROJECT-21590156
[Journal Article] Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies.2010
- Author(s)
  Yasuda H, Yanagihara K, Nakayama K, Mio T, Sasaki T, Asada M, Yamaya M, Fukushima M.
- Journal Title
  
  Nitric Oxide and Cancer: Prognosis and Therapy (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Associations between glutathione S-trans ferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy2010
- Author(s)
  Kanai M, Ishiguro H(12番目), Yanagihara K, etal
- Journal Title
  
  Cancer Epidemiol
  
  Volume: Vol.34 Issue: 2 Pages: 189-93
- DOI
  10.1016/j.canep.2010.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590533
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer2010
- Author(s)
  Yanagihara K, Yoshimura K, Niimi M, Yasuda H, et al.
- Journal Title
  
  Cancer Chemother Pharmacol (In press)
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small cell lung cancer2010
- Author(s)
  Yanagihara K, Yoshimura K, Ishiguro H, et al.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590533
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer.2010
- Author(s)
  Yanagihara K, Yoshimura K, Niimi M, Yasuda H, et. al.
- Journal Title
  
  Cancer Chemother Pharmacol (in press)
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer2010
- Author(s)
  Yanagihara K, Ishiguro H(7番目), et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: Vol.66 Issue: 5 Pages: 13-8
- DOI
  10.1007/s00280-009-1239-7
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590533
[Journal Article] Dual antibody plus chemotherapy in metastatic colorectal cancer.2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 339-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] A history of smoking is inversely correlated with the incidence of gemcitabine-induced neutropenia2009
- Author(s)
  Kanai M, Ishiguro H(11番目), Yanagihara K, etal
- Journal Title
  
  Ann Oncol
  
  Volume: Vol.20 Issue: 8 Pages: 1397-401
- DOI
  10.1093/annonc/mdp008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590533
[Journal Article] Nitric oxide and cancer immunity in solid tumor tissues2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 338-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Nitric oxide and cancer immunity in solid tumor tissues.2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 338-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Fas signal and cancer progression.2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 337-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Fas signal and cancer progression2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 337-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Dual antibody plus chemotherapy in metastatic colorectal cancer2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 339-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Prolonged neutropenia after dose-dense chemo the rapy with pegfilgrastim2008
- Author(s)
  Ishiguro H(1番目), Yanagihara K, et al
- Journal Title
  
  Ann Oncol
  
  Volume: Vol.19 Issue: 5 Pages: 1019-20
- DOI
  10.1093/annonc/mdn051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590533
[Journal Article] 外来化学療法と副作用対策:入院化学療法から外来化学療法へ2007
- Author(s)
  石黒洋、柳原一広
- Journal Title
  
  腫瘍内科 1
  
  Pages: 213-8
- Data Source
  KAKENHI-PROJECT-19590533
[Presentation] Degree of freezing does not affect frozen glove efficacy for prevention of docetaxel-induced nail toxicity in breast cancer patients2011
- Author(s)
  Ishiguro H, Yanagihara K, et al
- Organizer
  Multinational Associationof Supportive Care in Cancer(MASCC)
- Place of Presentation
  Athens, Greece
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-19590533
[Presentation] 市販後の当院におけるElrotinib使用症例の検討2009
- Author(s)
  永井宏樹, 柳原一広, 石黒洋, 他
- Organizer
  日本臨床腫瘍学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-19590533
[Presentation] これからのがん医療を支える医療人をどう育成するか2008
- Author(s)
  柳原一広, 金井雅史, 石黒洋, 福島雅典
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋国際会議場・名古屋
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590511
[Presentation] これからのがん医療を支える医療人をどう育成するか2008
- Author(s)
  柳原一広、金井雅史、石黒洋、福島雅典
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590511
[Presentation] 臨床腫瘍医の育成はどうあるべきか : 本邦での現状と今後の課題これからのがん医療を支える医療人をどう育成するか2008
- Author(s)
  柳原一広, 金井雅史, 石黒洋, 他
- Organizer
  日本癌治療学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590533
[Presentation] PHASE II STUDY OF COMBINATION CHEMOTHERAPY WITH S-1 PLUS DOCETAXEL FOR PREVIOUSLY TREATED PATIENTS WITH NON-SMALL-CELL LUNG CANCER IN A SECOND OR THIRD LINE REGIMEN.2008
- Author(s)
  Yanagihara K, Yasuda H, Niimi M, et al.
- Organizer
  ESMO 2008
- Place of Presentation
  Stockholm, Sweeden
- Year and Date
  2008-09-15
- Data Source
  KAKENHI-PROJECT-19689018

1. ISHIGURO Hiroshi (20422925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. YASUDA Hiroyasu (90396482)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. NISHIMURA Takafumi (40378732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUKUSHIMA Masanori (80107820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KANAI Masashi (70432416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. MISAWA Akiko (10378755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIRAIDE Atsushi (20199037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YANO Ikuko (50273446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. WADA Makoto (10359820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKECHI Tatsuo (80281682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ONISHI Hideki (30275028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TERADA Tomohiro (10324641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUKUDO Masahide (60437233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HATANO Etsuro (80359801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. UENO Takayuki (40452362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAMBA Tomomi (20402836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TERAMUKAI Satoshi (20359798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TANAKA Fumihiro (10283673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MIYAHARA Ryo (20335285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. WADA Hiromi (90167205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. IKENAKA Kazuhiro (00144527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MATSUMOTO Shigemi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KITANO Toshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yanagihara Kazuhiro 柳原 一広

YANAGIHARA Kazuhiro 柳原 一広

Research Projects

Research Products

Co-Researchers

Construction of administration algorithm of novel oral molecular-targeted anti-cancer drugs based on the clarificationof interindividual differences of pharmacokinetics and pharmacodynamics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Educational system of oncologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Standardization of tailor-made chemotherapy based on pharmacokinetics and pharmacogenomics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of Patients' Needs who are receiving chemotherapy at ambulatory settings: multi-institutional study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The basic and clinical research regarding development of combinationalchemotherapy with nitric oxide donating drugs for non-small cell lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Systemic Analysis of Sugar Chains in Non-Small Lung Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] がん化学療法と患者ケア 改訂第2版2007

Author(s)

Publisher

Data Source

[Journal Article] Degree of freezing does not affect efficacy of frozen gloves for prevention of do cetaxel-induced nail toxicity in breast cancer patients2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies.2010

Author(s)

Journal Title

Data Source

[Journal Article] Associations between glutathione S-trans ferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small cell lung cancer2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer2010

Author(s)

Journal Title

DOI

NAID

Yanagihara Kazuhiro 柳原一広

YANAGIHARA Kazuhiro 柳原一広

[Book] がん化学療法と患者ケア改訂第2版2007