Takehara Tetsuo 竹原徹郎

… Alternative Names

TAKEHARA Tetsuo 竹原徹郎

Less

Researcher Number	70335355
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院医学系研究科, 教授 2016 – 2021: 大阪大学, 医学系研究科, 教授 2012 – 2015: 大阪大学, 医学(系)研究科(研究院), 教授 2013 – 2014: 大阪大学, 大学院医学系研究科, 教授 2011 – 2012: 大阪大学, 大学院・医学系研究科, 教授 … More 2010 – 2012: 大阪大学, 医学系研究科, 教授 2011: 大阪大学, 医学研究科, 教授 2011: 大阪大学, 医学系・研究科, 准教授 2011: 大阪大学, 医学系・研究科, 教授 2011: 大阪大学, 大学院・医学系・研究科, 教授 2010: Osaka University, 院医学系研究科, 教授 2007 – 2010: Osaka University, Graduate School of Medicine, Associate Professor 2002 – 2006: 大阪大学, 医学系研究科, 助教授 2005: 大阪大学, 医学研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Biological Sciences / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator アポトーシス / 肝癌 / オートファジー / 肝臓 / 肝細胞 / NK細胞 / ノックアウトマウス / NKG2D / MICA / 脂肪肝 … More / マウス / 膵癌 / ネクローシス / 非アポトーシス型細胞死 / ミトコンドリアDNA / MICB / Innate immunity / Liver / NKレセプター / 肝がん / 自然免疫 / 獲得免疫 / 先天免疫 / 肝発癌 / 消化器内科学 / マウスモデル / 急性膵炎 / 肝細胞癌 / Mcl-1 / Bcl-xL / C型肝炎 / ソラフェニブ / 免疫 / 癌 / NASH / 遺伝子導入 / 慢性炎症 / 多核球系骨髄由来免疫抑制細胞 / 癌微小環境 / P53 / 肝前駆細胞 / 細胞老化 / p53 / 細胞死 / Gab1 / GDF15 / 酸化ストレス / 肝星細胞 / マクロファージ / CIRPSR/Cas / 単一細胞解析 / レンチウイルス / エレクトロポレーション / 転移 / シングルセル解析 / HLA / 免疫逃避 / 肝転移 / Lipophagy / 脂肪細胞 / Tumor / NK receptor / HCC / Soluble MICB / Soluble MICA / 自然免 / TAE / 肝硬変 / Virus / Liver cancer / Hepatitis C / NK cell / Cancer / Immunology / HLA-E / NKG2A / 樹状細胞 / ウイルス / tumor / innate immunity / interferon α / interleukin-12 / α-galactosyl ceramide / liver / cancer / natural killer T cell / natural killer cell / 抗腫瘍免疫 / IFN_γ / CDld / α-GalCer / 腫瘍 / 遺伝子治療 / 腫瘍免疫 / IL-12 / IFNα / NKT細胞 / 発癌 / CTGF / Kras / 脂肪性肝疾患 / 非アルコール性脂肪性肝疾患 / Rubicon / STAT3 / 膵炎 / Atg-7 / Atg7 / 脂肪肝炎 / 非アルコール性脂肪肝炎 / Cre / ノックアウト / apoptosis / Bid / 肝線維化 / Bak / Bcl-2 / shedding / 抗癌剤 / 免疫治療 / sorafenib / MIC / 炎症 / IL-1 / ADAM / 自己消化 / 代謝疾患 / GFP-LC3 / 非アルコール性脂肪性肝炎 / 酵素抗体法 / LC3 / MCD / 抗ウイルス治療 / IFN / B型肝炎 / Precore変異 / YMDD変異 / 酵素阻害剤 / 遺伝子解析 / 耐性ウイルス / ラミブジン / HBV … More Except Principal Investigator 肝癌 / 樹状細胞 / RIG-I / C型肝炎 / インターフェロン / 制御性T細胞 / NK細胞 / リバビリン / α-galactosylceramide / EphA2 / Toll-like receptor / Th1 / バイオマーカー / CTOS / 薬剤耐性 / 獲得免疫 / 自然免疫 / 免疫 / インターフェロンα / Toll様受容体 / APOB蛋白 / iPS細胞 / ペーシング細胞 / カハール介在細胞 / APOB48 / CIPO / 慢性偽性腸閉塞症 / 過敏性腸症候群 / 便秘 / 慢性偽性腸閉塞 / Relaxed-circular (RC) HBV DNA / HBV mutation / Hepatitis B virus (HBV) / 環状2本鎖(RC)HBV DNA / HBV変異 / B型肝炎ウイルス(HBV) / Interleukin 12 / Cancer Immunotherapy / Dendritic cell / Liver cancer / インターロイキン12 / 癌免疫治療 / Regulatory T cells / Ribavirin / Pegylated interferon-a / Dendritic cells / Chronic hepatitis C / Th2 / ペグインターフェロンα / C型慢性肝炎 / NK receptor / innate immuni / natural killer cell / dendritic cell / hepatocellular carcinoma / chronic hepatitis C / IL-15 / IFNα / Pseudo-HCV / サブセット / B / MICA / 先天免疫 / blood DC / IL-10 / FoxP3 / 持続ALT正常 / ペグインターフェロン / regulatory T細胞 / Toll様レセプター / NKレセプター / 肝がん / 炎症 / let-7 / 胃炎 / 腸上皮化生 / CagA / ヘリコバクターピロリ / 胃癌 / 膵癌 / 膵臓癌 / 肝繊維化 / CTGF / 分子標的治療薬 / 抗癌剤耐性 / 抗癌剤感受性 / スクリーニング / 薬剤感受性 / 単離培養 / 個別化医療 / オーダーメード医療 / 分子標的治療 / 化学療法 / 大腸癌 / 骨髄系前駆細胞 / TIE2 / 血管新生 / HAS2 / VEGD / STAT3 / HIF-1 / IFN / VEGF / HCC / STAT1 / PI3キナーゼ / マイクロRNA / mTOR / ウイルス粒子形成 / BCAA / C型肝炎ウイルス / NK細胞サブセット / STAT / 免疫細胞 / シグナル伝達 / 癌免疫 / 癌幹細胞 / 線維化 / 血小板 / Trl / 肝細胞癌 / ELISPOT / HCV / T細胞 / ノックアウト / ウイルス肝炎 / 肝癌免疫治療 / ナノテクノロジー / Type III IFN / HCVプロテアーゼ阻害剤 Less

Mechanisms of cancer cell clonal expansion via phenotypic and spatial diversity in the cancer microenvironment.Principal Investigator
- Principal Investigator
  
  Takehara Tetsuo
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Elucidation of hepatic progenitor cell-derived carcinogenic mechanism via p53 activation in hepatocytesPrincipal Investigator
- Principal Investigator
  
  Takehara Tetsuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
Elucidation of the mechanism of pancreatic cancer metastasis using single cell analysis technology and innovative mouse modelsPrincipal Investigator
- Principal Investigator
  
  Takehara Tetsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Cell-to-cell communication and pathogenesis triggered by hepatocyte cell death in the liverPrincipal Investigator
- Principal Investigator
  
  Tetsuo Takehara
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
障害ミトコンドリアからのダイイングコード漏出による脂肪性肝疾患の進展機序の解明Principal Investigator
- Principal Investigator
  
  竹原徹郎
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
肝細胞と脂肪細胞におけるRubiconを介した脂肪代謝の制御Principal Investigator
- Principal Investigator
  
  竹原徹郎
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Treatment for acute pancreatitis by regulating autophagy which modulates zymogen granules and inflammasomesPrincipal Investigator
- Principal Investigator
  
  Takehara Tetsuo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Development of experimental model of Chronic Intestinal Pseudo-obstruction (CIPO) using iPS and drug discovery research
- Principal Investigator
  
  Tsujii Masahiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
The impact of hepatocyte apoptosis and autophagy in the process of livercarcinogenesisPrincipal Investigator
- Principal Investigator
  
  Takehara Tetsuo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Significance of connective tissue growth factor (CTGF) and tumor-stroma interaction in Kras-driven hepatocarcinogenesis and HCC progressionPrincipal Investigator
- Principal Investigator
  
  Takehara Tetsuo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Development of biomarkers using cancer cells derived from clinical samples
- Principal Investigator
  
  TSUJII Masahiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
肝細胞CTGFによる肝線維化・肝発癌制御機構の解明
- Principal Investigator
  
  小玉尚宏
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
膵癌におけるバイオマーカーの探索ーＣＴＯＳ法を用いた検討
- Principal Investigator
  
  NISHIDA Tsutomu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Molecular mechanisms of acinar cell injury in acute pancreatitisPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Crosstalk between CagA and inflammation in H. pylori-related gastric carcinogenesis.
- Principal Investigator
  
  TSUJII Masahiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Regulation of autophagy and its impact in the development and progression of hepatocellular cancer.Principal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Development of novel therapy for hepatocellular carcinoma targeting of bone marrow-derived angiogenesis precursor
- Principal Investigator
  
  KANTO Tatsuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Immunological analysis of liver cancer stem cells and immunotherapy
- Principal Investigator
  
  TATSUMI Tomohide
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Analysis of interferon-τsignaling in immune cells of patients with hepatitis C virus infection to establish effective therapeutic strategy.
- Principal Investigator
  
  MIYAGI Takuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Controlling HCV replication by targeting intracellular signaling
- Principal Investigator
  
  ISHIDA Hisashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  独立行政法人国立病院機構大阪医療センター(臨床研究センター)
  Osaka University
The role of STATs molecule through cancer development
- Principal Investigator
  
  HOSUI Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Bcl-2 network and regulation of cell death in non-alcoholic steatohepatitisPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Immunological analysis and new immunotherapy of chronic hepatitis C
- Principal Investigator
  
  MOCHIZUKI Kiyoshi, HAYASHI Norio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Molecular mechanism of the ectodomain shedding of the NKG2D ligand MHC class I-related chain A in hepatocellular carcinoma and its therapeutic implicationPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Developmental research on dendritic cell-based immunotherapy against chronic hepatitis C and hepatocellular carcinoma
- Principal Investigator
  
  KANTO Tatsuya
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Analysis of activation of dendritic cells by γ-PGA nano-particle and liver cancer immunotherapy
- Principal Investigator
  
  TATSUMI Tomohide
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
非アルコール性脂肪性肝疾患と肝硬変におけるオートファジーの解析とその意義の解明Principal Investigator
- Principal Investigator
  
  竹原徹郎
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Molecular regulation of NK cell cytotoxicity fir human hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Hepatitis B virus mutations affecting synthesis of relaxed-circular viral DNA : Relation to disease severity
- Principal Investigator
  
  OHKAWA Kazuyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
HBV遺伝子導入マウスでの酵素阻害剤誘発変異の解析とテーラーメイド医療への応用Principal Investigator
- Principal Investigator
  
  竹原徹郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Molecular analysis of dendritic cell based vaccines against liver cancer
- Principal Investigator
  
  TATSUMI Tomohide
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Natural killer receptor-mediated regulation of dendritic cell functions in chronic hepatitis CPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Establishment of plasmacytoid dendritic cell-based immune therapy against viral hepatitis and hepatocellular carcinoma
- Principal Investigator
  
  KANTO Tatsuya
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Regulation of dendritic cell function and cell-based therapy in chronic hepatitis C virus infection
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Suppression of hepatocarcinogenesis by activating natural killer T cellsPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Tetsuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University

[Book] Molecules, Systems and Signaling in Liver Injury2017
- Author(s)
  Hayato Hikita、Tetsuo Takehara
- Publisher
  Springer
- ISBN
  9783319581057
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Book] The　オートファジー　研究者たちの集大成が見える最新ビジュアルテキスト非アルコール性脂肪性肝疾患の病態進展における肝細胞オートファジーの影響2017
- Author(s)
  疋田隼人、竹原徹郎
- Publisher
  羊土社
- ISBN
  9784758103657
- Data Source
  KAKENHI-PROJECT-26253047
[Book] The　オートファジー　研究者たちの集大成が見える最新ビジュアルテキスト非アルコール性脂肪性肝疾患の病態進展における肝細胞オートファジーの影響2017
- Author(s)
  疋田隼人、竹原徹郎
- Publisher
  羊土社
- ISBN
  9784758103657
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Book] 肝細胞死の研究と進歩, Annual Review 消化器2014
- Author(s)
  疋田隼人, 竹原徹郎, 林紀夫, 日比紀文, 上西紀夫, 下瀬川徹
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23390197
[Book] Annual Review消化器 20142014
- Author(s)
  疋田隼人、竹原徹郎.
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23390197
[Book] Hepatology Practice 2 NASH・アルコール性肝障害の診療を極める.2013
- Author(s)
  竹井謙之,竹原徹郎, 持田　智.
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23390197
[Book] Hepatology Practice 2 NASH・アルコール性肝障害の診療を極める2013
- Author(s)
  竹井謙之, 竹原徹郎, 持田智
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23390197
[Book] 肝胆膵領域(NK細胞による肝癌認識機構の分子機序の解析と新規治療法の探索.消化器病学の進歩-原点から未来への情報発信-II)(編集飯田三雄発行)(東京)2009
- Author(s)
  竹原徹郎
- Publisher
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20390208
[Book] Innate immunity in type C hepatitis. Hepatitis C virus disease.2008
- Author(s)
  Takehara T, Hayashi N
- Publisher
  Immunobiology and clinical applications. Edited by Emilio Jirillo. Springer, USA
- Data Source
  KAKENHI-PROJECT-15109006
[Book] Innate immunity in type C hepatitis. Hepatitis C virus disease.2008
- Author(s)
  Takehara T, Hayashi N
- Publisher
  Immunobiology and clinical applications. Edited by Emilio Jirillo. Springer, USA.
- Data Source
  KAKENHI-PROJECT-18390216
[Book] Innate immunity in type C hepatitis. Hepatitis C virus disease.2008
- Author(s)
  Takehara T, Hayashi N
- Publisher
  Immunobiology and clinical applications. Edited by Emilio jirillo. Springer, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Book] Innate immunity in type C hepatitis. Hepatitis C virus disease.2008
- Author(s)
  Takehara T, Hayashi N
- Publisher
  Regulation of the NKG2D immunoreceptor by soluble MICA during transcatheter arterial embolization for hepatocellular carcinoma.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity2023
- Author(s)
  Okabe J, Kodama T, Sato Y, Shigeno S, Matsumae T, Daiku K, Sato K, Yoshioka T, Shigekawa M, Higashiguchi M, Kobayashi S, Hikita H, Tatsumi T, Okamoto T, Satoh T, Eguchi H, Akira S, Takehara T.
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 9;42 Issue: 1 Pages: 262-262
- DOI
  10.1186/s13046-023-02831-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18260, KAKENHI-PROJECT-22K19527, KAKENHI-ORGANIZER-22H05060, KAKENHI-PLANNED-22H05061, KAKENHI-PROJECT-20H05693, KAKENHI-PROJECT-23K27584
[Journal Article] Pentraxin 3 is an adipose tissue‐related serum marker for pancreatic cancer cachexia predicting subsequent muscle mass and visceral fat loss2022
- Author(s)
  Sato Katsuhiko、Hikita Hayato、Shigekawa Minoru、Kato Seiya、Sasaki Yoichi、Shinkai Kazuma、Fukuoka Makoto、Kudo Shinnosuke、Sato Yu、Fukumoto Kenji、Shirai Kumiko、Myojin Yuta、Sakane Sadatsugu、Murai Kazuhiro、Yoshioka Teppei、Nishio Akira、Kodama Takahiro、Sakamori Ryotaro、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4311-4326
- DOI
  10.1111/cas.15569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19527, KAKENHI-PROJECT-22K16043
[Journal Article] Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non-Cell Autonomous Liver Carcinogenesis2022
- Author(s)
  Makino Yuki、Hikita Hayato、Fukumoto Kenji、Sung Ji Hyun、Sakano Yoshihiro、Murai Kazuhiro、Sakane Sadatsugu、Kodama Takahiro、Sakamori Ryotaro、Kondo Jumpei、Kobayashi Shogo、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Cancer Research
  
  Volume: 82 Issue: 16 Pages: 2860-2873
- DOI
  10.1158/0008-5472.can-21-4390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03661, KAKENHI-PROJECT-21H02903
[Journal Article] Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis and tumorigenesis2021
- Author(s)
  Mizutani N, Hikita H, Saito Y, Myojin Y, Sato K, Urabe M, Kurahashi T, Shiode Y, Sakane S, Murai K, Nozaki Y, Kodama T, Sakamori R, Yoshida Y, Tatsumi T, Takehara T.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: in press Issue: 6 Pages: G958-G968
- DOI
  10.1152/ajpgi.00370.2020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08307, KAKENHI-PROJECT-18H02795, KAKENHI-PROJECT-20H03661
[Journal Article] Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production2021
- Author(s)
  Myojin Y, Hikita H, Sugiyama M, Sasaki Y, Fukumoto K, Sakane S, Makino Y, Takemura N, Yamada R, Shigekawa M, Kodama T, Sakamori R, Kobayashi S, Tatsumi T, Suemizu H, Eguchi H, Kokudo N, Mizokami M, Takehara T.
- Journal Title
  
  Gastroenterology .
  
  Volume: 160 Issue: 5 Pages: 1741-1754
- DOI
  10.1053/j.gastro.2020.12.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08307, KAKENHI-PROJECT-18H02795, KAKENHI-PROJECT-20H03661, KAKENHI-PROJECT-19K17489
[Journal Article] Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration2021
- Author(s)
  Nozaki Y, Hikita H, Tanaka S, Fukumoto K, Urabe M, Sato K, Myojin Y, Doi A, Murai K, Sakane S, Saito Y, Kodama T, Sakamori R, Tatsumi T, Takehara T.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 3363-3363
- DOI
  10.1038/s41598-021-83082-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08307, KAKENHI-PROJECT-18H02795, KAKENHI-PROJECT-20H03661
[Journal Article] Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels2020
- Author(s)
  Sato Katsuhiko、Hikita Hayato、Myojin Yuta、Fukumoto Kenji、Murai Kazuhiro、Sakane Sadatsugu、Tamura Takeshi、Yamai Takuo、Nozaki Yasutoshi、Yoshioka Teppei、Kodama Takahiro、Shigekawa Minoru、Sakamori Ryotaro、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 7 Pages: e0235573-e0235573
- DOI
  10.1371/journal.pone.0235573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19546
[Journal Article] Endoscopic biliary stenting as the risk factor for cholangitis after endoscopic ultrasound in patients with biliary strictures2020
- Author(s)
  Ikezawa Kenji、Shigekawa Minoru、Yamai Takuo、Suda Takahiro、Kegasawa Tadashi、Yoshioka Teppei、Sakamori Ryotaro、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: in press Issue: 5 Pages: 1263-1266
- DOI
  10.1111/jgh.15264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19546
[Journal Article] Risk Factors for Pancreatic Cancer and the Necessity of Long-Term Surveillance in Patients With Pancreatic Cystic Lesions2020
- Author(s)
  Yoshioka Teppei、Shigekawa Minoru、Ikezawa Kenji、Tamura Takeshi、Sato Katsuhiko、Urabe Makiko、Sueyoshi Hironari、Yamai Takuo、Suda Takahiro、Sakamori Ryotaro、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Pancreas
  
  Volume: 49 Issue: 4 Pages: 552-560
- DOI
  10.1097/mpa.0000000000001521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19546
[Journal Article] Forkhead Box M1 Transcription Factor Drives Liver Inflammation Linking to Hepatocarcinogenesis in Mice2020
- Author(s)
  Kurahashi Tomohide、Yoshida Yuichi、Ogura Satoshi、Egawa Mayumi、Furuta Kunimaro、Hikita Hayato、Kodama Takahiro、Sakamori Ryotaro、Kiso Shinichi、Kamada Yoshihiro、Wang I-Ching、Eguchi Hidetoshi、Morii Eiichi、Doki Yuichiro、Mori Masaki、Kalinichenko Vladimir V.、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 9 Issue: 3 Pages: 425-446
- DOI
  10.1016/j.jcmgh.2019.10.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04160, KAKENHI-PROJECT-18H02795, KAKENHI-PROJECT-17K09422, KAKENHI-PROJECT-17K09424
[Journal Article] DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway2018
- Author(s)
  Saito Yoshinobu、Hikita Hayato、Nozaki Yasutoshi、Kai Yugo、Makino Yuki、Nakabori Tasuku、Tanaka Satoshi、Yamada Ryoko、Shigekawa Minoru、Kodama Takahiro、Sakamori Ryotaro、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Cell Death & Differentiation
  
  Volume: 26 Issue: 3 Pages: 470-486
- DOI
  10.1038/s41418-018-0131-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09422, KAKENHI-PUBLICLY-17H05508, KAKENHI-PROJECT-18H02795, KAKENHI-PROJECT-17K09423
[Journal Article] Cardiac metastasis from colon cancer effectively treated with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab: a case report.2017
- Author(s)
  Tsujii Y, Hayashi Y, Maekawa A, Fujinaga T, Nagai K, Yoshii S, Sakatani A, Hiyama S, Shinzaki S, Iijima H, Takehara T.
- Journal Title
  
  BMC Cancer.
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1186/s12885-017-3147-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation.2017
- Author(s)
  Kawai S, Iijima H, Shinzaki S, Hiyama S, Yamaguchi T, Araki M, Iwatani S, Shiraishi E, Mukai A, Inoue T, Hayashi Y, Tsujii M, Motooka D, Nakamura S, Iida T, Takehara T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Evaluation of endoscopic entire 3D image acquisition of the digestive tract using a stereo endoscope2017
- Author(s)
  Kayo Yoshimoto, Kenji Watabe, Tetsuji Fujinaga, Hideki Iijima, Masahiko Tsujii, Hideya Takahashi, Tetsuo Takehara, Kenji Yamada
- Journal Title
  
  Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV
  
  Volume: Proc. SPIE Pages: 10054-10054
- DOI
  10.1117/12.2250774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-15K09057
[Journal Article] A novel pathogenesis of inflammatory bowel disease from the perspective of glyco-immunology.2017
- Author(s)
  Shinzaki S, Iijima H, Fujii H, Kamada Y, Naka T, Takehara T, Miyoshi E.
- Journal Title
  
  J Biochem.
  
  Volume: 印刷中 Issue: 5 Pages: 409-415
- DOI
  10.1093/jb/mvx010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-16K09310, KAKENHI-PROJECT-15H04810, KAKENHI-PROJECT-16H05226, KAKENHI-PROJECT-16K15428
[Journal Article] Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis2017
- Author(s)
  Shinzaki, S., Matsuoka, K., Iijima, H., Mizuno, S., Serada, S., Fujimoto, M., Arai, N. Koyama, N., Morii, E., Watanabe, M., Hibi, T., Kanai, T., Takehara, T., Naka, T.
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 11(1) Issue: 1 Pages: 84-91
- DOI
  10.1093/ecco-jcc/jjw132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460969, KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-16K09310, KAKENHI-PROJECT-17H04159
[Journal Article] Age at onset is associated with the seasonal pattern of onset and exacerbation in inflammatory bowel disease2017
- Author(s)
  Araki, M, Shinzaki, S., Yamada, T., Arimitsu S., Komori, M., Shibukawa, N., Mukai A., Nakajima, S., Kinoshita, K., Kitamura, S., Murayama, Y., Ogawa H., Yasunaga Y, Oshita, M., Fukui, H., Masuda E., Tsujii, M., Hiyama, S., Inoue, T., Iijima, H., Takehara, T.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 11 Pages: 1149-1157
- DOI
  10.1007/s00535-017-1313-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460969, KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-16K09310, KAKENHI-PROJECT-17H04159
[Journal Article] N-Acetylglucosaminyltransferase V exacerbates murine colitis with macrophage dysfunction and enhances colitic tumorigenesis.2016
- Author(s)
  Shinzaki S, Ishii M, Fujii H, Iijima H, Wakamatsu K, Kawai S, Shiraishi E, Hiyama S, Inoue T, Hayashi Y, Kuwahara R, Takamatsu S, Kamada Y, Morii E, Tsujii M, Takehara T, Miyoshi E.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 51 Issue: 4 Pages: 357-369
- DOI
  10.1007/s00535-015-1119-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J08881, KAKENHI-PROJECT-25860535, KAKENHI-PROJECT-15H04810, KAKENHI-PROJECT-26460969, KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-16K15428
[Journal Article] N-Acetylglucosaminyltransferase V exacerbates murine colitis with macrophage dysfunction and enhances colitic tumorigenesis.2016
- Author(s)
  Shinzaki S, Ishii M, Fujii H, Iijima H, Wakamatsu K, Kawai S, Shiraishi E, Hiyama S, Inoue T, Hayashi Y, Kuwahara R, Takamatsu S, Kamada Y, Morii E, Tsujii M, Takehara T, Miyoshi E.
- Journal Title
  
  J Gastroenterol
  
  Volume: 51 Issue: 4 Pages: 357-69
- DOI
  10.1007/s00535-015-1112-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460969, KAKENHI-PROJECT-14J08881, KAKENHI-PROJECT-25860535, KAKENHI-PROJECT-15K15292
[Journal Article] Narrow-band imaging with magnifying endoscopy for Peyer's patches is useful in predicting the recurrence of remissive patients with ulcerative colitis.2016
- Author(s)
  Hiyama S, Iijima H, Kawai S, Mukai A, Shiraishi E, Iwatani S, Yamaguchi T, Araki M, Hayashi Y, Shinzaki S, Mizushima T, Tsujii M, Takehara T.
- Journal Title
  
  Intest Res.
  
  Volume: 14 Pages: 314-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Core Fucosylation on T cells, Required for Activation of T-cell Receptor Signaling and Induction of Colitis in Mice, is Increased in Patients with Inflammatory Bowel Disease.2016
- Author(s)
  Fujii H, Shinzaki S, Iijima H, Wakamatsu K, Iwamoto C, Sobajima T, Kuwahara R, Hiyama S, Hayashi Y, Takamatsu S, Uozumi N, Kamada Y, Tsujii M, Taniguchi N, Takehara T, Miyoshi E
- Journal Title
  
  Gastroenterology
  
  Volume: 未定 Issue: 7 Pages: 00297-3
- DOI
  10.1053/j.gastro.2016.03.002
- NAID
  40021255019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460969, KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-14J08881, KAKENHI-PROJECT-25860535, KAKENHI-PROJECT-16K09310, KAKENHI-PROJECT-16K15428
[Journal Article] Core Fucosylation on T Cells, Required for Activation of T-Cell Receptor Signaling and Induction of Colitis in Mice, Is Increased in Patients With Inflammatory Bowel Disease.2016
- Author(s)
  Fujii H, Shinzaki S, Iijima H, Wakamatsu K, Iwamoto C, Sobajima T, Kuwahara R, Hiyama S, Hayashi Y, Takamatsu S, Uozumi N, Kamada Y, Tsujii M, Taniguchi N, Takehara T, Miyoshi E.
- Journal Title
  
  Gastroenterology.
  
  Volume: 150 Pages: 1620-1632
- NAID
  40021255019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Clinical problems with antithrombotic therapy for endoscopic submucosal dissection for gastric neoplasms.2016
- Author(s)
  Yoshio T, Nishida T, Hayashi Y, Iijima H, Tsujii M, Fujisaki J, Takehara T.
- Journal Title
  
  World J Gastrointest Endosc.
  
  Volume: 16 Issue: 20 Pages: 756-762
- DOI
  10.4253/wjge.v8.i20.756
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Role of aberrant IgG glycosylation in the pathogenesis of inflammatory bowel disease.2016
- Author(s)
  Miyoshi E, Shinzaki S, Fujii H, Iijima H, Kamada Y, Takehara T.
- Journal Title
  
  Proteomics Clinical Applications
  
  Volume: 未定 Issue: 4 Pages: 384-390
- DOI
  10.1002/prca.201500089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460969, KAKENHI-PROJECT-14J08881, KAKENHI-PROJECT-25860535, KAKENHI-PROJECT-15H04810, KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-16K15428
[Journal Article] Esophagogastric junctional adenocarcinoma originating from endoscopically unrecognizable Barrett's epithelium.2016
- Author(s)
  Nagai K, Tsujii Y, Matsui T, Yoshii S, Fujinaga T, Maekawa A, Inoue T, Hayashi Y, Shinzaki S, Iijima H, Tsujii M, Morii E, Takehara T.
- Journal Title
  
  Dis Esophagus.
  
  Volume: 29 Issue: 8 Pages: 1164-1166
- DOI
  10.1111/dote.12396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth.2016
- Author(s)
  Hayashi Y, Tsujii M, Kodama T, Akasaka T, Kondo J, Hikita H, Inoue T, Tsujii Y, Maekawa A, Yoshii S, Shinzaki S, Watabe K, Tomita Y, Inoue M, Tatsumi T, Iijima H, Takehara T.
- Journal Title
  
  Carcinogenesis.
  
  Volume: 37 Issue: 10 Pages: 972-984
- DOI
  10.1093/carcin/bgw085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292, KAKENHI-PROJECT-15K19326, KAKENHI-PROJECT-15K08391, KAKENHI-PROJECT-15K09057
[Journal Article] Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.2016
- Author(s)
  Tanaka S, Hikita H, Tatsumi T, Sakamori R, Nozaki Y, Sakane S, Shiode Y, Nakabori T, Saito Y, Hiramatsu N, Tabata K, Kawabata T, Hamasaki M, Eguchi H, Nagano H, Yoshimori T, Takehara T.
- Journal Title
  
  Hepatology
  
  Volume: 64 Issue: 6 Pages: 1994-2014
- DOI
  10.1002/hep.28820
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01204, KAKENHI-PROJECT-26253047, KAKENHI-PROJECT-15H04371
[Journal Article] Percutaneous endoscopic gastrostomy under steady pressure automatically controlled endoscopy: First clinical series.2016
- Author(s)
  Imaeda H, Nakajima K, Hosoe N, Nakahara M, Zushi S, Kato M, Kashiwagi K, Matsumoto Y, Kimura K, Nakamura R, Wada N, Tsujii M, Yahagi N, Hibi T, Kanai T, Takehara T, Ogata H.
- Journal Title
  
  World J Gastrointest Endosc.
  
  Volume: in press Issue: 3 Pages: 186-186
- DOI
  10.4253/wjge.v8.i3.186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] "Underwater" endoscopic submucosal dissection: a novel technique for complete resection of a rectal neuroendocrine tumor.2016
- Author(s)
  Yoshii S, Hayashi Y, Matsui T, Aoi K, Tsujii Y, Iijima H, Takehara T.
- Journal Title
  
  Endoscopy.
  
  Volume: 48 Issue: S 01 Pages: E67-E68
- DOI
  10.1055/s-0042-101855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Clinical outcomes of endoscopic submucosal dissection for superficial esophageal neoplasms: a multicenter retrospective cohort study.2015
- Author(s)
  Tsujii Y, Nishida T, Nishiyama O, Yamamoto K, Kawai N, Yamaguchi S, Yamada T, Yoshio T, Kitamura S, Nakamura T, Nishihara A, Ogiyama H, Nakahara M, Komori M, Kato M, Hayashi Y, Shinzaki S, Iijima H, Michida T, Tsujii M, Takehara T.
- Journal Title
  
  Endoscopy
  
  Volume: 47 Issue: 09 Pages: 775-783
- DOI
  10.1055/s-0034-1391844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] 5FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53‑mutated colon cancer cells.2015
- Author(s)
  Akasaka T, Tsujii M, Kondo J, Hayashi Y, Ying J, Lu Y, Kato M, Yamada T, Yamamoto S, Inoue T, Tsujii Y, Maekawa A, Fujinaga T, Shiraishi E, Hiyama S, Inoue T, Shinzaki S, Watabe K, Nishida T, Iijima H, Takehara T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 46 Issue: 1 Pages: 63-70
- DOI
  10.3892/ijo.2014.2693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591011, KAKENHI-PROJECT-25860535, KAKENHI-PROJECT-15K15292
[Journal Article] The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells.2015
- Author(s)
  Ying J, Tsujii M, Kondo J, Hayashi Y, Kato M, Akasaka T, Inoue T, Shiraishi E, Inoue T, Hiyama S, Tsujii Y, Maekawa A, Kawai S, Fujinaga T, Araki M, Shinzaki S, Watabe K, Nishida T, Iijima H, Takehara T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 46 Issue: 4 Pages: 1151-1159
- DOI
  10.3892/ijo.2015.2851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591011, KAKENHI-PROJECT-15K09057, KAKENHI-PROJECT-15K15292
[Journal Article] Polyglycolic acid sheets for repair of refractory esophageal fistula.2015
- Author(s)
  Tsujii Y, Kato M, Shinzaki S, Takigawa A, Hayashi Y, Nishida T, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Endoscopy.
  
  Volume: 47 Issue: S 01 Pages: 39-40
- DOI
  10.1055/s-0034-1390914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-15K15292
[Journal Article] Gastric endoscopic submucosal dissection under steady pressure automatically controlled endoscopy (SPACE); a multicenter randomized preclinical trial.2015
- Author(s)
  Yamada T, Hirota M, Tsutsui S, Kato M, Takahashi T, Yasuda K, Sumiyama K, Tsujii M, Takehara T, Mori M, Doki Y, Nakajima K.
- Journal Title
  
  Surg Endosc.
  
  Volume: ahead
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] Solitary Fibrous Tumor of the Liver from Development to Resection2015
- Author(s)
  Makino Y, Miyazaki M, Shigekawa M, Ezaki H, Sakamori R, Yakushijin T, Ohkawa K, Kato M, Akasaka T, Shinzaki S, Nishida T, Miyake Y, Hama N, Nagano H, Honma K, Morii E, Wakasa K, Hikita H, Tatsumi T, Iijima H, Hiramatsu N, Tsujii M, Takehara T.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 7 Pages: 765-770
- DOI
  10.2169/internalmedicine.54.3053
- NAID
  130005063222
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Renal dysfunction is an independent risk factor for bleeding after gastric ESD.2015
- Author(s)
  Yoshioka T, Nishida T, Tsujii M, Kato M, Hayashi Y, Komori M, Yoshihara H, Nakamura T, Egawa S, Yoshio T, Yamada T, Yabuta T, Yamamoto K, Kinoshita K, Kawai N, Ogiyama H, Nishihara A, Michida T, Iijima H, Shintani A, Takehara T.
- Journal Title
  
  Endosc Int Open.
  
  Volume: 3 Issue: 01 Pages: E39-E45
- DOI
  10.1055/s-0034-1390762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Chemoradiotherapy is effective for primary esophageal adenosquamous cell carcinoma but ineffective for the metastatic adenocarcinoma component2015
- Author(s)
  Nozaki Y, Nishida T, Hori Y, Shinzaki S, Kato M, Yakushijin T, Iijima H, Tsujii M, Morii E, Takehara T.
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 112 Issue: 2 Pages: 278-286
- DOI
  10.11405/nisshoshi.112.278
- NAID
  130004776875
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-15K15292
[Journal Article] Gastric endoscopic submucosal dissection under steady pressure automatically controlled endoscopy (SPACE); a multicenter randomized preclinical trial.2015
- Author(s)
  Yamada T, Hirota M, Tsutsui S, Kato M, Takahashi T, Yasuda K, Sumiyama K, Tsujii M, Takehara T, Mori M, Doki Y, Nakajima K.
- Journal Title
  
  Surg Endosc.
  
  Volume: 29 Issue: 9 Pages: 2748-2755
- DOI
  10.1007/s00464-014-4001-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Integrated diagnostic strategy for the invasion depth of early gastric cancer by conventional endoscopy and EUS.2015
- Author(s)
  sujii Y, Kato M, Inoue T, Yoshii S, Nagai K, Fujinaga T, Maekawa A, Hayashi Y, Akasaka T, Shinzaki S, Watabe K, Nishida T, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 15 Issue: 3 Pages: 452-459
- DOI
  10.1016/j.gie.2015.01.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-15K09057, KAKENHI-PROJECT-15K15292
[Journal Article] Endoscopic submucosal dissection in early gastric cancer in elderly patients and comorbid conditions.2015
- Author(s)
  Nishida T, Kato M, Yoshio T, Akasaka T, Yoshioka T, Michida T, Yamamoto M, Hayashi S, Hayashi Y, Tsujii M, Takehara T.
- Journal Title
  
  World J Gastrointest Endosc.
  
  Volume: 7 Issue: 5 Pages: 524-531
- DOI
  10.4253/wjge.v7.i5.524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Clinical outcomes of endoscopic submucosal dissection for superficial esophageal neoplasms: a multicenter retrospective cohort study.2015
- Author(s)
  Tsujii Y, Nishida T, Nishiyama O, Yamamoto K, Kawai N, Yamaguchi S, Yamada T, Yoshio T, Kitamura S, Nakamura T, Nishihara A, Ogiyama H, Nakahara M, Komori M, Kato M, Hayashi Y, Shinzaki S, Iijima H, Michida T, Tsujii M, Takehara T.
- Journal Title
  
  Endoscopy.
  
  Volume: ahead
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] Localized gastric amyloidosis mimicking a submucosal tumor-like gastric cancer.2015
- Author(s)
  Yamaguchi T, Inoue T, Nishida T, Kato M, Hayashi Y, Tsujii Y, Maekawa A, Kawai S, Fujinaga T, Araki M, Nagai K, Yoshii S, Hiyama S, Shinzaki S, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 82 Issue: 1 Pages: 175-177
- DOI
  10.1016/j.gie.2015.01.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Effectiveness of anti-tumor necrosis factor-α therapy in Crohn's disease with abscesses around the sigmoid colon: a case report2015
- Author(s)
  Nagai K, Shinzaki S, Kato M, Hiyama S, Yakushijin T, Nishida T, Iijima H, Ookawa K, Tsujii M, Takehara T.
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 112 Issue: 4 Pages: 707-713
- DOI
  10.11405/nisshoshi.112.707
- NAID
  130005060962
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15292
[Journal Article] Esophageal adenocarcinoma with white opaque substance observed by magnifying endoscopy with narrow band imaging.2014
- Author(s)
  Yoshii S, Kato M, Honma K, Fujinaga T, Tsujii Y, Maekawa A, Inoue T, Hayashi Y, Akasaka T, Shinzaki S, Nishida T, Iijima H, Tsujii M, Morii E, Takehara T.
- Journal Title
  
  Dig Endosc.
  
  Volume: 27 Issue: 3 Pages: 392-396
- DOI
  10.1111/den.12331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-25860535
[Journal Article] Clinical features of post-polypectomy bleeding associated with heparin bridge therapy.2014
- Author(s)
  Inoue T, Nishida T, Maekawa A, Tsujii Y, Akasaka T, Kato M, Hayashi Y, Yamamoto S, Kondo J, Yamada T, Shinzaki S, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Dig Endosc.
  
  Volume: 26 Issue: 2 Pages: 243-249
- DOI
  10.1111/den.12123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365, KAKENHI-PROJECT-25860535
[Journal Article] Endoscopic surveillance strategy after endoscopic resection for early gastric cancer.2014
- Author(s)
  Nishida T, Tsujii M, Kato M, Hayashi Y, Akasaka T, Iijima H, Takehara T.
- Journal Title
  
  World J Gastrointest Pathophysiol.
  
  Volume: 5 Issue: 2 Pages: 100-106
- DOI
  10.4291/wjgp.v5.i2.100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] Esophageal early basaloid squamous carcinoma with unusual narrowband imaging magnified endoscopy findings.2014
- Author(s)
  Kai Y, Kato M, Hayashi Y, Akasaka T, Shinzaki S, Nishida T, Tsujii M, Morii E, Takehara T.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 20 Issue: 35 Pages: 12673-12677
- DOI
  10.3748/wjg.v20.i35.12673
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-25860535
[Journal Article] Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease.2014
- Author(s)
  Mukai A, Iijima H, Hiyama S, Fujii H, Shinzaki S, Inoue T, Shiraishi E, Kawai S, Araki M, Hayashi Y, Kondo J, Mizushima T, Kanto T, Egawa S, Nishida T, Tsujii M, Takehara T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49 Issue: 12 Pages: 1524-1535
- DOI
  10.1007/s00535-013-0923-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] 急性膵炎における転写因子の関わり2014
- Author(s)
  重川稔、竹原徹郎
- Journal Title
  
  膵臓
  
  Volume: 29 Pages: 38-44
- NAID
  130004496048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659364
[Journal Article] Adiponectin inhibits murine pancreatic cancer growth.2014
- Author(s)
  Kato M, Watabe K, Tsujii M, Funahashi T, Shimomura I, Takehara T.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: 59 Issue: 6 Pages: 1192-1196
- DOI
  10.1007/s10620-014-3175-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591011
[Journal Article] Esophageal submucosal dissection under steady pressure automatically controlled endoscopy (SPACE): a clinical feasibility study.2014
- Author(s)
  Kato M, Nakajima K, Yamada T, Hirota M, Miyazaki Y, Yamasaki M, Nishida T, Mori M, Doki Y, Tsujii M, Takehara T.
- Journal Title
  
  Endoscopy.
  
  Volume: 46 Issue: 08 Pages: 680-684
- DOI
  10.1055/s-0034-1365465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] Comparative study of esomeprazole and lansoprazole in triple therapy for eradication of Helicobacter pylori in Japan.2014
- Author(s)
  Nishida T, Tsujii M, Tanimura H, Tsutsui S, Tsuji S, Takeda A, Inoue A, Fukui H, Yoshio T, Kishida O, Ogawa H, Oshita M, Kobayashi I, Zushi S, Ichiba M, Uenoyama N, Yasunaga Y, Ishihara R, Yura M, Komori M, Egawa S, Iijima H, Takehara T.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 20 Issue: 15 Pages: 4362-4369
- DOI
  10.3748/wjg.v20.i15.4362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] Atypical duodenal ulcer and invagination caused by a large pedunculated duodenal Brunner's gland hamartoma.2014
- Author(s)
  Nakabori T, Shinzaki S, Yamada T, Nishida T, Iijima H, Tsujii M, Kurokawa Y, Mori M, Doki Y, Morii E, Takehara T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 79 Issue: 4 Pages: 679-680
- DOI
  10.1016/j.gie.2013.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365
[Journal Article] Concomitant use of romiplostim and chemotherapy for advanced rectal cancer associated with idiopathic thrombocytopenic purpura2014
- Author(s)
  Yamada M, Shinzaki S, Nishida T, Yamada T, Fujinaga T, Yakushijin T, Tatsumi T, Iijima H, Hiramatsu N, Tsujii M, Takehara T.
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 111 Pages: 521-528
- NAID
  130003392015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Lymph node enlargement after definitive chemoradiotherapy for clinical stage I esophageal squamous cell carcinoma.2014
- Author(s)
  Hayashi Y, Nishida T, Tsujii M, Tsutsui S, Yamamoto K, Isohashi F, Yamasaki M, Miyata H, Kato M, Yamada T, Shinzaki S, Iijima H, Ogawa K, Doki Y, Takehara T.
- Journal Title
  
  BMC Cancer.
  
  Volume: 14 Issue: 1 Pages: 706-706
- DOI
  10.1186/1471-2407-14-706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] Peyer's patches play a protective role in nonsteroidal anti-inflammatory drug-induced enteropathy in mice.2014
- Author(s)
  Hiyama S, Iijima H, Shinzaki S, Inoue T, Shiraishi E, Kawai S, Araki M, Kato M, Hayashi Y, Nishida T, Fujii H, Mukai A, Shibata N, Sato S, Kiyono H, Gotoh K, Motooka D, Nakamura S, Iida T, Tsujii M, Takehara T.
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: 5 Issue: 5 Pages: 790-9
- DOI
  10.1097/mib.0000000000000017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J08881, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23590941, KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-26460969
[Journal Article] Acute suppurative pancreatic ductitis associated with pancreatic duct obstruction.2013
- Author(s)
  Fujinaga T, Nishida T, Miyazaki M, Shigekawa M, Ikezawa K, Iwahashi K, Inoue T, Yamada T, Ezaki H, Shinzaki S, Yakushijin T, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Endoscopy
  
  Volume: 45 Issue: S 02 Pages: 135-135
- DOI
  10.1055/s-0032-1326450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365
[Journal Article] TIE2-expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlated with angiogenesis2013
- Author(s)
  Matsubara, T., Kanto, T., Kuroda, S., Yoshio, S., Higashitani, K., Kakita, N., Miyazaki, M., Sakakibara, M., Hiramatsu, N., Kasahara, A., Tomimaru, Y., Tomokuni, A., Nagano, H., Hayashi, N. and Takehara, T.
- Journal Title
  
  Hepatology
  
  Volume: 57 Pages: 1416-1425
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Evaluation of endoscopic ultrasound image quality is necessary in endosonographic assessment of early gastric cancer invasion depth2013
- Author(s)
  Yamamoto S, Nishida T, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Gastroenterol Res Pract
  
  Pages: 164530-164530
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/?term=endosonographic+assessment+of+yamamoto+s
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Mucosa-associated lymphoid tissue (MALT) lymphoma of the esophagus.2013
- Author(s)
  Tsujii Y, Nishida T, Kato M, et al.
- Journal Title
  
  Dis Esophagus. 2013 Apr : 26(3) : 349-50.
  
  Volume: 26.(Epub 2012 Aug 7.) Issue: 3 Pages: 349-350
- DOI
  10.1111/j.1442-2050.2012.01387.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24659365
[Journal Article] Lectin-based immunoassay for aberrant IgG glycosylation as the biomarker for Crohn's disease.2013
- Author(s)
  Shinzaki S, 他13名, Naka T, Plevy S E, Takehara T, Miyoshi E.
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: 19（2） Issue: 2 Pages: 321-31
- DOI
  10.1097/mib.0b013e318280eade
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591101, KAKENHI-PROJECT-23590941, KAKENHI-PROJECT-24590972, KAKENHI-PROJECT-24659365, KAKENHI-PROJECT-25860535
[Journal Article] Functional Network between Bone and Organs. Gastrointestinal diseases and bone.2013
- Author(s)
  Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Clin Calcium.
  
  Volume: 23 Pages: 243-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188
[Journal Article] The Bcl-2 homology 3 (BH3)-only proteins Bim and Bid are functionally active and restrained by anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) family proteins in healthy liver.2013
- Author(s)
  [1] Kodama T, Hikita H, Kawaguchi T, Saito Y, Tanaka S, Shigekawa M, Shimizu S, Li W, Miyagi T, Kanto T, Hiramatsu N, Tatsumi T, Takehara T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 42 Pages: 30009-30018
- DOI
  10.1074/jbc.m112.443093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390197, KAKENHI-PROJECT-24590970, KAKENHI-PROJECT-24590973, KAKENHI-PROJECT-24790694, KAKENHI-PROJECT-25460994
[Journal Article] The Bcl-2 homology 3 (BH3)-only proteins Bim and Bid are functionally active and restrained by anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) family proteins in healthy liver2013
- Author(s)
  Kodama T, Hikita H, Kawaguchi T, Saito Y, Tanaka S, Shigekawa M, Shimizu S, Li W, Miyagi T, Kanto T, Hiramatsu N, Tatsumi T, Takehara T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Pages: 30009-30018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390197
[Journal Article] CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis.2013
- Author(s)
  Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, Jin Y, Li W, Nakamura T, Nishida T, Iijima H, Tsuji S, Kawano S, Hayashi N, Takehara T.
- Journal Title
  
  GUT
  
  Volume: 62 Issue: 11 Pages: 1536-1546
- DOI
  10.1136/gutjnl-2011-301625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365
[Journal Article] Post-transplant lymphoproliferative disorder of the ileum diagnosed by double-balloon enteroscopy.2013
- Author(s)
  Tawara S, Shinzaki S, Nishida T, Kato M, Hiyama S, Inoue T, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Endoscopy.
  
  Volume: 45 Issue: S 02 Pages: 380-381
- DOI
  10.1055/s-0033-1344828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365
[Journal Article] Gastric ESD under Heparin Replacement at High-Risk Patients of Thromboembolism Is Technically Feasible but Has a High Risk of Delayed Bleeding: Osaka University ESD Study Group.2013
- Author(s)
  Yoshio T, Nishida T, Kawai N, Yuguchi K, Yamada T, Yabuta T, Komori M, Yamaguchi S, Kitamura S, Iijima H, Tsutsui S, Michida T, Mita E, Tsujii M, Takehara T.
- Journal Title
  
  Gastroenterol Res Pract.
  
  Volume: 2013 Pages: 365830-365830
- DOI
  10.1155/2013/365830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365
[Journal Article] Amelioration of Small Bowel Injury by Switching from Nonselective Nonsteroidal Anti-Inflammatory Drugs to Celecoxib in Rheumatoid Arthritis Patients: A Pilot Study2013
- Author(s)
  Inoue, T., Iijima, H., Arimitsu, J., Hagihara, K., Kawai, S., Shiraishi, E., Hiyama, S., Mukai, A., Shinzaki, S., Nishida, T., Ogata, A., Tsujii, M., Takehara, T.
- Journal Title
  
  Digestion
  
  Volume: 89 Issue: 2 Pages: 124-132
- DOI
  10.1159/000357229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590941, KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365, KAKENHI-PROJECT-25860535
[Journal Article] Functional Network between Bone and Organs. Gastrointestinal diseases and bone2013
- Author(s)
  Iijima, H. Tsujii, M. Takehara, T.
- Journal Title
  
  Clin Calcium
  
  Volume: 23 Pages: 243-248
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Choroidal and cutaneous metastasis from gastric adenocmcinoma.2013
- Author(s)
  Kawai S, Nishida T, Hayashi Y, et al.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 19 Issue: 9 Pages: 1485-1488
- DOI
  10.3748/wjg.v19.i9.1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365
[Journal Article] Esophageal pyogenic granuloma developed after short-term fol low-up.2013
- Author(s)
  Saito Y, Nishida T, Kato M, et al.
- Journal Title
  
  Dis Esophagus
  
  Volume: 26(Epub 2012 May 9.) Issue: 3 Pages: 343-344
- DOI
  10.1111/j.1442-2050.2012.01351.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24659365
[Journal Article] Hemobilia into a metallic biliary stent due to pseudoaneurysm: a case report2013
- Author(s)
  Morishita N, Nishida T, Hayashi Y, Iwahashi K, Ikezawa K, Shigekawa M, Shinzaki S, Yamada T, Kakita N, Ezaki H, Miyazaki M, Yakushijin T, Tatsumi T, Iijima H, Kiso S, Hiramatsu N, Tsujii M, Osuga K, Terashima K, Takehara T.
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 110 Pages: 2127-2135
- NAID
  130003383333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Managing hepatitis B virus carriers with systemic chemotherapy or biologic therapy in the outpatient clinic.2013
- Author(s)
  Nishida T
- Journal Title
  
  Hepatol Res.
  
  Volume: 43 Issue: 4 Pages: 339-346
- DOI
  10.1111/j.1872-034x.2012.01073.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591036, KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24659365, KAKENHI-PROJECT-25461419
[Journal Article] Narrow Band Imaging with Magnifying Endoscopy for Peyer's Patches in Patients with Inflammatory Bowel Disease2013
- Author(s)
  Hiyama, S., Iijima, H., Shinzaki, S., Mukai, A., Inoue, T., Shiraishi, E., Kawai, S., Yamada, T., Nishida, T., Tsujii, M., Takehara, T.
- Journal Title
  
  Digestion
  
  Volume: 87 Issue: 4 Pages: 269-80
- DOI
  10.1159/000349953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590941, KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24591012, KAKENHI-PROJECT-24659365, KAKENHI-PROJECT-25860535
[Journal Article] Scheduled endoscopic surveillance controls secondary cancer after curative endoscopic resection for early gastric cancer : a multicentre retrospective cohort study by Osaka University ESD study group2013
- Author(s)
  Kato M, Nshida T, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Gut
  
  Volume: 62 Issue: 10 Pages: 1425-1432
- DOI
  10.1136/gutjnl-2011-301647
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma2012
- Author(s)
  Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N
- Journal Title
  
  Int J Cancer
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Bak deficiency inhibits liver carcinogenesis : A causal link between apoptosis and carcinogenesis2012
- Author(s)
  Hikita H, Takehara T, et al
- Journal Title
  
  Journal of Hepatology
  
  Volume: (印刷中) Issue: 1 Pages: 92-100
- DOI
  10.1016/j.jhep.2012.01.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188, KAKENHI-PROJECT-23390197, KAKENHI-PROJECT-24590970, KAKENHI-PROJECT-24590973, KAKENHI-PROJECT-24790694
[Journal Article] Bak deficiency inhibits liver carcinogenesis : a causal link between apoptosis and carcinogenesis2012
- Author(s)
  Hikita H, Kodama T, Shimizu S, Li W, Shigekawa M, Tanaka S, Hosui A, Miyagi T, Tatsumi T, Kanto T, Hiramatsu N, Morii E, Hayashi N, Takehara T
- Journal Title
  
  J Hepatol
  
  Volume: 57 Pages: 92-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390197
[Journal Article] Protective role of adiponec t in against ethanol-induced gastric injury in mice.2012
- Author(s)
  Yamamoto S, ffatabe K, Araki H, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 302(Epub 2012 Feb 9) Issue: 8 Pages: G773-G780
- DOI
  10.1152/ajpgi.00324.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24590972, KAKENHI-PROJECT-24591011, KAKENHI-PROJECT-24659365
[Journal Article] Bak deficiency inhibits liver carcinogenesis : A causal link between apoptosis and carcinogenesi2012
- Author(s)
  Hikita H, Kodama T, Shimizu S, Li W, Shigekawa M, Tanaka S, Hosui A, Miyagi T, Tatsumi T, Kanto T, Hiramatsu N, Morii E, Hayashi N, Takehara T
- Journal Title
  
  J Hepatol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Suppression of signal transducers and activators of transcription 1(STAT1) in hepatocellular carcinoma is associated with tumor progression2012
- Author(s)
  Hosui A(1番目), Takehara T(12番目), 他10名
- Journal Title
  
  Int J Cancer
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590845
[Journal Article] Dynamics of regulatory T cells and plasmacytoid dendritic cells as immune markers for virological response in pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C patients.2012
- Author(s)
  Kanto, T., Inoue, M., Oze, T., Miyazaki, M., Sakakibara, M., Kakita, N., Matsubara, T., Higashitani, K., Hagiwara, H., Iio, S., Katayama, K., Mita, E., Kasahara, A., Hiramatsu, N., Takehara, T. and Hayashi, N
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 169-178
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Fibroblast growth factor-2 enhances NK sensitivity of hepatocellular carcinoma cells.2012
- Author(s)
  Tsunematsu, H., Tatsumi, T., Kohga, K., Yamamoto, M., Aketa, H., Miyagi, T., Hosui, A., Hiramatsu, N., Kanto, T., Hayashi, N. and Takehara, T
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 356-364
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Fibroblast growth factor-2 enhances NK sensitivity of hepatocellular carcinoma cells2012
- Author(s)
  Tsunematsu H, Tatsumi T(2番目), Takehara T(11番目)(他8名)
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 356-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Epste in-Barr virus-associated early gastric cancer presenting as an elevated lesion.2012
- Author(s)
  Yamamoto S, Nishida T, Tsujii M, et al.
- Journal Title
  
  Endoscopy
  
  Volume: 44(Epub 2012 May 23.) Issue: S 02 Pages: 222-223
- DOI
  10.1055/s-0032-1309353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24659365
[Journal Article] Inhibition of autophagy potentiates the anti-tumor effect of the multi-kinase inhibitor sorafenib in hepatocellular carcinoma2012
- Author(s)
  Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N
- Journal Title
  
  Int J Cancer
  
  Volume: 131 Pages: 548-557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390197
[Journal Article] Deficiency of N-acetylgalactosamine in O-linked oligosaccharides of IgA is a novel biologic marker for inflammatory bowel diseases.2012
- Author(s)
  InoueT, Miyoshi E, et al.
- Journal Title
  
  IBD Journal
  
  Volume: 18(9) Issue: 9 Pages: 1723-34
- DOI
  10.1002/ibd.22876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249038, KAKENHI-PROJECT-22790643, KAKENHI-PROJECT-23390081, KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-24659365
[Journal Article] Comparative analyses of regulatory T cell subsets in patients with hepatocellular carcinoma: a crucial role of CD25(-) FOXP3(-) T cells2012
- Author(s)
  Kakita, N., Kanto, T., Itose, I., Kuroda, S., Inoue, M., Matsubara, T., Higashitani, K., Miyazaki, M., Sakakibara, M., Hiramatsu, N., Takehara, T., Kasahara, A. and Hayashi, N
- Journal Title
  
  Int J Cancer
  
  Volume: 31 Pages: 2573-2583
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction2012
- Author(s)
  Shigekawa M, Hikita H, Kodama T, Shimizu S, Li W, Uemura A, Miyagi T, Hosui A, Kanto T, Hiramatsu N, Tatsumi T, Takeda K, Akira S, Takehara T.
- Journal Title
  
  Am J Pathol
  
  Volume: 101 Pages: 2105-2113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659364
[Journal Article] Altered oligosaccharide structures contribute to ameliorate murine colitis defective in beta 1,4 galactosyltransferase I.2012
- Author(s)
  Shinzaki S, Miyoshi E, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 142(5) Issue: 5 Pages: 1172-82
- DOI
  10.1053/j.gastro.2012.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249038, KAKENHI-PROJECT-22300142, KAKENHI-PROJECT-22790643, KAKENHI-PROJECT-23650232, KAKENHI-PROJECT-24659365
[Journal Article] Pancreatitis STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction2012
- Author(s)
  Shigekawa M, Tatsumi T, et al.
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 181 Issue: 6 Pages: 2105-2113
- DOI
  10.1016/j.ajpath.2012.08.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590973, KAKENHI-PROJECT-24659364, KAKENHI-PROJECT-24790694
[Journal Article] Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice2011
- Author(s)
  Kodama T, Takehara T(2番目), Hosui A(9番目), 他18名
- Journal Title
  
  J. Clin. Invest
  
  Volume: 121(8) Pages: 3343-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590845
[Journal Article] Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.2011
- Author(s)
  Shimizu, S., Takehara, T., Hikita, H., Kodama, T., Tsunematsu, H., Miyagi, T., Hosui, A., Ishida, H., Tatsumi, T., Kanto, T., Hiramatsu, N., Fujita, N., Yoshimori, T. and Hayashi, N
- Journal Title
  
  Int J Cancer
  
  Volume: 131 Pages: 548-557
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] α-galactosylceramide activates antitumor immunity against liver tumor2011
- Author(s)
  Tatsumi T(1番目), Takehara T(2番目)(他7名)
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 160-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Hepatitis C virus (HCV)-specific CD8+ T cell responses during pegylated interferon-alfa and ribavirin treatment are associated with the antiviral activity in patients with chronic hepatitis C virus infection.2011
- Author(s)
  Tatsumi T, Takehara T, et al.
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.2011
- Author(s)
  Tatsumi T, Takehara T, Kanto T (6番目), 他
- Journal Title
  
  Hepatol Res 41
  
  Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Amino acid substitution in the core protein has no impact on relapse in hepatitis C genotype 1 patients treated with peginterferon and ribavirin2011
- Author(s)
  Inoue Y, Tatsumi T(14番目), Takehara T(18番目)(他16名)
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 419-427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-αand ribavirin combination therapy in patients with chronic hepatitis C virus infection2011
- Author(s)
  Tatsumi T(1番目), Takehara T(2番目)(他8名)
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] alpha-Galactosylceramide activates antitumor immunity against liver tumor.2011
- Author(s)
  Tatsumi, T., Takehara, T., Miyagi, T., Sugiyama, T., Aketa, H., Sasakawa, A., Kanto, T., Hiramatsu, N. and Hayashi, N
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 160-169
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Differential alteration of CD56^<bright> and CD56^<dim> natural killer cells in frequency, phenotype, and cytokine response in chronic hepatitis C virus infection2011
- Author(s)
  MIYAGI, T., SHIMIZU, S., TATSUMI, T., NISHIO, K., HIRAMATSU, N., KANTO, T., HAYASHI, N. & TAKEHARA, T.
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Pages: 1020-30
- NAID
  10029563284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590842
[Journal Article] Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice2011
- Author(s)
  Shigekawa M, Takehara T(2番目), Tatsumi T(9番目)(他10名)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 614-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Alternations in microRNA expression profile in HCV-infected hepatoma cells : Involvement of miR-491 in regulation of HCV replication via PI3 kinase/ Akt pathway2011
- Author(s)
  Ishida H, Tatsumi T(2番目), Takehara T(11番目)(他8名)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 92-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/ Bax-deficient mice2011
- Author(s)
  Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N
- Journal Title
  
  Hepatology
  
  Volume: 54 Pages: 240-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fasactivation in Bak/Bax-deficient mice2011
- Author(s)
  Hikita, H.
- Journal Title
  
  Hepatology
  
  Volume: VOL. 54 Issue: 1 Pages: 240-251
- DOI
  10.1002/hep.24305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0316, KAKENHI-PROJECT-21590841, KAKENHI-PROJECT-21659188, KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-23657084
[Journal Article] Alterations in microRNA expression profile in HCV-infected hepatoma cells : involvement of miR-491 in regulation of HCV via the PI3 kinase/Akt pathway2011
- Author(s)
  Ishida H, Tatsumi T, Hosui A, Nawa T, Kodama T, Shimizu S, Hikita H, Hiramatsu N, Kanto T, Hayashi N, Takehara T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: Vol.412 Pages: 92-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590843
[Journal Article] BH3-only activator proteins, Bid and Bim, are dispensable for Bak/ Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency : Molecular requisites for the mitochondrial pathway to apoptosis in platelets2011
- Author(s)
  Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Yin XM, Hayashi N
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 13905-13913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] and Hayashi, N., Amino acid substitution in the core protein has no impact on relapse in hepatitis C genotype 1 patients treated with peginterferon and ribavirin2011
- Author(s)
  Inoue, Y., Hiramatsu, N., Oze, T., Yakushijin, T., Mochizuki, K., Fukuda, K., Mita, E., Haruna, Y., Inoue, A., Imai, Y., Hosui, A., Miyagi, T., Yoshida, Y., Tatsumi, T., Kiso, S., Kanto, T., Kasahara, A., Takehara, T
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 419-427
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Hepatitis C virus (HCV)-specific CD8+ T cell responses during pegylated interferon-alfa and ribavirin treatment are associated with the antiviral activity in patients with chronic hepatitis C virus infection.2011
- Author(s)
  Tatsumi T, Takehara T, Miyagi T, Nakazuru S, Mita E, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  Hepatol Res 41
  
  Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Alterations in microRNA expression profile in HCV-infected hepatoma cells : involvement of miR-491 in regulation of HCV via the PI3 kinase/Akt pathway2011
- Author(s)
  Ishida H, Tatsumi T, Takehara T, et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Issue: 1 Pages: 92-97
- DOI
  10.1016/j.bbrc.2011.07.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590843
[Journal Article] Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice2011
- Author(s)
  Shigekawa M, Takehara T(2番目)、Hosui A(8番目), 他10名
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 406(4) Pages: 614-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590845
[Journal Article] Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice2011
- Author(s)
  Shigekawa, M., Takehara, T., et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 614-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice2011
- Author(s)
  Kodama T, Takehara T(2番目), Tatsumi T(10番目)(他18名)
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Pages: 3343-3356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] ・-galactosylceramide activates antitumor immunity against liver tumor.2011
- Author(s)
  Tatsumi T, Takehara T, Miyagi T, Sugiyama T, Aketa H, Sasakawa A, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  Hepatol Res 41
  
  Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] BH3-only activator proteins Bid and Bim are dispensable for Bak/ Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency2011
- Author(s)
  Kodama T, Takehara T(2番目), Tatsumi T(9番目)(他10名)
- Journal Title
  
  J Bio Chem
  
  Volume: 286(16) Pages: 13905-13913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Indications and limitations for aged patients with chronic hepatitis C in pegylated interferon alfa-2b plus ribavirin combination therapy.2011
- Author(s)
  Oze T, Kanto T (23番目), Takehara T (25番目), 他
- Journal Title
  
  J Hepatol 54
  
  Pages: 604-611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma2011
- Author(s)
  Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N
- Journal Title
  
  Int.J.Cancer
  
  Volume: 131 Issue: 3 Pages: 548-57
- DOI
  10.1002/ijc.26374
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020023, KAKENHI-PROJECT-22590729, KAKENHI-PROJECT-22770194, KAKENHI-PROJECT-23247034, KAKENHI-PROJECT-23390197, KAKENHI-PROJECT-23657129, KAKENHI-ORGANIZER-20113001, KAKENHI-PLANNED-20113002
[Journal Article] α-fetoprotein impairs activation of NK cells by inhibiting the function of dendritic cells2011
- Author(s)
  Yamamoto M, Tatsumi T(2番目), Takehara T(10番目)(他7名)
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 165 Pages: 211-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Increases ill p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice2011
- Author(s)
  Kodama, T., et al
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 121 Issue: 8 Pages: 3343-3356
- DOI
  10.1172/jci44957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109008, KAKENHI-PROJECT-21590845, KAKENHI-PROJECT-21592360, KAKENHI-PROJECT-23390197
[Journal Article] Comprehensive immunological analyses of colorectal cancer patients in the phase I/II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic antigen peptide2011
- Author(s)
  Sakakibara, M., Kanto, T., Hayakawa, M., Kuroda, S., Miyatake, H., Itose, I., Miyazaki, M., Kakita, N., Higashitani, K., Matsubara, T., Hiramatsu, N., Kasahara, A., Takehara, T.and Hayashi, N
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 60 Pages: 1565-1575
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice2011
- Author(s)
  Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Tsunematsu H, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Kubota S, Takigawa M, Tomimaru Y, Tomokuni A, Nagano H, Doki Y, Mori M, Hayashi N
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Pages: 3343-3356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/ Bax-deficient mice2011
- Author(s)
  Hikita H, Takehara T(2番目), Tatsumi T(8番目)(他12名)
- Journal Title
  
  Hepatology
  
  Pages: 240-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] α-galactosylceramide activates antitumor immunity against liver tumor.2011
- Author(s)
  Tatsumi T, Takehara T, Kanto T (7番目), 他
- Journal Title
  
  Hepatol Res 41
  
  Pages: 160-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] nvolvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice2011
- Author(s)
  Shigekawa, M., Takehara, T., Kodama, T., Hikita, H., Shimizu, S., Li, W., Miyagi, T., Hosui, A., Tatsumi, T., Ishida, H., Kanto, T., Hiramatsu, N. and Hayashi, N
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 614-620
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma2010
- Author(s)
  Kohga K, Tatsumi T(2番目), Takehara T(3番目)(他6名)
- Journal Title
  
  J Hepatol
  
  Volume: 52 Pages: 872-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Sorafenib inhibits the shedding of MICA on hepatocellular cacrcinoma cell by downregulating ADAM9.2010
- Author(s)
  Kohga K, Takehara T, 他
- Journal Title
  
  Hepatology 51
  
  Pages: 1264-1273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] The let-7 family of microRNAs negatively regulates Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma.2010
- Author(s)
  Shimizu S, Takehara T, et al.
- Journal Title
  
  J Hepatol
  
  Volume: 52 Pages: 698-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] The let7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma2010
- Author(s)
  Shimizu S, Takehara T(2番目), Tatsumi T(7番目)(他10名)
- Journal Title
  
  J Hepatol
  
  Volume: 52 Pages: 698-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.2010
- Author(s)
  Hikita H, Takehara T, et al.
- Journal Title
  
  Hepatology
  
  Volume: 52 Pages: 1310-1321
- NAID
  40018998703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] STAT3 signaling within hepatocyte is required for anemia of inflammation in vivo2010
- Author(s)
  Sakamori R, Takehara T(2番目), Tatsumi T(3番目)(他5名)
- Journal Title
  
  J Gastroenterology
  
  Volume: 45 Pages: 244-248
- NAID
  10027214771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Fatal exacerbation of type B chronic hepatitis trigged by changes in relaxed circular viral DNA synthesis and virion secretion2010
- Author(s)
  Ohkawa K, Takehara T(2番目), Tatsumi T(14番目)(他13名)
- Journal Title
  
  Biochemi Biophys Res Commun
  
  Volume: 394 Pages: 87-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Natural killer cell is a major producer of interferon γ that is critical for the IL-12-induced anti-tumor effect in mice.2010
- Author(s)
  Uemura A, Takehara T, et al.
- Journal Title
  
  Cancer Immunol Immunother 59
  
  Pages: 453-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice2010
- Author(s)
  Kodama T, Takehara T(2番目), Tatsumi T(8番目)(他11名)
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 2487-2498
- NAID
  40017376760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] STAT3 signaling within hepatocyte is required for anemia of inflammation in vivo.2010
- Author(s)
  Sakamori R, Takehara T, KantoT (7番目), 他
- Journal Title
  
  J Gastroenterol 45
  
  Pages: 244-248
- NAID
  10027214771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet.2010
- Author(s)
  Miyagi, T., Takehara, T., Uemura, A., Nishio, K., Shimizu, S., Kodama, T., Hikita, H., Li, W., Sasakawa, A., Tatsumi, T., Ohkawa, K., Kanto, T., Hiramatsu, N. and Hayashi, N
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1247-1254
- NAID
  10027700169
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Natural killer cell is a major producer of interferon γ that is critical for the IL-12-induced anti-tumor effect in mice.2010
- Author(s)
  Uemura A, Takehara T, et al.
- Journal Title
  
  Cancer Immunol Immunother 59
  
  Pages: 453-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Natural killer cell is a major producer of interferon・that is critical for the IL-12-induced anti-tumor effect in mice.2010
- Author(s)
  Uemura A, Takehara T, Miyagi T, Suzuki T, Tatsumi T, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  Cancer Immunol Immunother 59
  
  Pages: 453-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Sorafenib inhibited the shedding of MICA on hepatocellular carcinoma cells by downregulating ADAM9.2010
- Author(s)
  Kohga K, Takehara T, et al.
- Journal Title
  
  Hepatology
  
  Volume: 51 Pages: 1264-1273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib2010
- Author(s)
  Hikita H, Takehara T(2番目), Tatsumi T(9番目)(他11名)
- Journal Title
  
  Hepatology
  
  Volume: 52 Pages: 1310-1321
- NAID
  40018998703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] alpha-Galactosylceramide activates antitumor immunity against liver tumor.2010
- Author(s)
  Tatsumi, T., Takehara, T., et al.
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 160-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Sorafenib inhibited the shedding of MICA on hepatocellular carcinoma cells by downregulating ADAM9.2010
- Author(s)
  Kohga K, Takehara T, Tatsumi T, Ishida H, Miyagi T, Hosui A, Hayashi N.
- Journal Title
  
  Hepatology 51
  
  Pages: 1264-1273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] HCV感染により変動するマイクロRRNAのHCV増殖に対する影響2010
- Author(s)
  石田永、竹原徹郎、林紀夫
- Journal Title
  
  消化器内科
  
  Volume: 51 Pages: 636-641
- Data Source
  KAKENHI-PROJECT-21590843
[Journal Article] Altered interferon-alpha-signaling in NK cells from the patients with chronic hepatitis C virus infection.2010
- Author(s)
  Miyagi T, Takehara T, Nishio K, Shimizu S, Kohga K, Tatsumi T, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  J Hepatol 53
  
  Pages: 424-430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet.2010
- Author(s)
  Miyagi T, Takehara T, Uemura A, Nishio K, Shimizu S, Kodama T, Hikita H, Li W, Sasakawa A, Tatsumi T, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  J Gastroenterol 45
  
  Pages: 1247-1254
- NAID
  10027700169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] HCV感染により変動するマイクロRNAのHCV増殖に対する影響2010
- Author(s)
  石田永、竹原徹郎、林紀夫
- Journal Title
  
  消化器内科
  
  Volume: 51巻 Pages: 636-641
- Data Source
  KAKENHI-PROJECT-21590843
[Journal Article] Lack of invariant natural killer cells elicits liver inflammation and predispores to liver fibrosis in mice fed with high-fat-diet.2010
- Author(s)
  Miyagi T, Takehara T, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1247-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Expression of CD133 confers malignant potential via inhibiting metalloproteinases in human hepatocellular carcinoma.2010
- Author(s)
  Kohga K, Tatsumi T, Takehara T, Miyagi T, Hayashi N.
- Journal Title
  
  J Hepatol 52
  
  Pages: 872-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Altered interferon-α-signaling in natural killer cells from patients with chronic hepatitis C virus infection2010
- Author(s)
  Miyagi T, Takehara T(2番目), Tatsumi T(7番目)(他7名)
- Journal Title
  
  J Hepatol
  
  Volume: 53 Pages: 424-430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib2010
- Author(s)
  Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N
- Journal Title
  
  Hepatology
  
  Volume: 52 Pages: 1310-1321
- NAID
  40018998703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet2010
- Author(s)
  Miyagi, T., Takehara, T., et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1247-1254
- NAID
  10027700169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] The let7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma.2010
- Author(s)
  Shimizu S, Takehara T, 他
- Journal Title
  
  J Hepatol 52
  
  Pages: 698-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Alterations in hepatitis B virus nucleotide sequences in a chronic virus carrier from immunotolerant to immunoactive phase2010
- Author(s)
  Ohkawa K, Takehara T(2番目), Tatsumi T(3番目), (他8名)
- Journal Title
  
  Biochemi Biophys Res Commun
  
  Volume: 394 Pages: 574-580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] The let-7 family of microRNAs negatively regulates Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma.2010
- Author(s)
  Shimizu S, Takehara T, et al.
- Journal Title
  
  J Hepatol
  
  Volume: 52 Pages: 698-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Altered interferon-τ-signaling in natural killer cells from patients with chronic hepatitis C virus infection2010
- Author(s)
  MIYAGI, T., TAKEHARA, T., NISHIO, K., SHIMIZU, S., KOHGA, K., LI, W., TATSUMI, T., HIRAMATSU, N., KANTO, T. & HAYASHI, N.
- Journal Title
  
  J Hepatol
  
  Volume: 53 Pages: 424-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590842
[Journal Article] STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo2010
- Author(s)
  Sakamori R, Takehara T, et al.
- Journal Title
  
  J Gastroenterol. 45
  
  Pages: 244-248
- NAID
  10027214771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590845
[Journal Article] EphA2-derived peptide vaccine with amphiphilic poly (γ-glutamic acid) nanoparticles elicits an antitumor effect against mouse liver tumor.2010
- Author(s)
  Yamaguchi S, Tatsumi T, Takehara T, Sasakawa A, Yamamoto M, Kohga K, Miyagi T, Kanto T, Hiramatsu N, Akagi T, Akashi M, Hayashi N.
- Journal Title
  
  Cancer Immunol Immunother 59
  
  Pages: 759-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] EphA2-derived peptide vaccine with amphiphilic poly(γ-gulutamic acid) nanoparticles elicits antitumor effect against mouse liver tumor2010
- Author(s)
  Yamaguchi S, Tatsumi T(2番目), Takehara T(3番目)(他9名)
- Journal Title
  
  EphA2-derived peptide vaccine with amphiphilic poly(γ-gulutamic acid) nanoparticles elicits antitumor effect against mouse liver tumor
  
  Volume: 59 Pages: 759-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice.2010
- Author(s)
  Kodama T, Takehara T, 他
- Journal Title
  
  Gastroenterology 138
  
  Pages: 2487-2498
- NAID
  40017376760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Sorafenib inhibits the shedding of major histocomaptibility complex class I-related chain A on hepatocellular cacrcinoma cells by down-regulating a disintegrin and metalloproteinase 92010
- Author(s)
  Kohga K, Takehara T(2番目), Tatsumi T(3番目)(他4名)
- Journal Title
  
  Hepatology
  
  Volume: 51 Pages: 1264-1273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice2010
- Author(s)
  Kodama T, Takehara T, Hikita H, Shimizu S, Wei Li, Miyagi T, Hosui A, Tatsumi T, Ishida H, Tadokoro S, Ido A, Tsubouchi H, Hayashi N
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 2487-2498
- NAID
  40017376760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor2010
- Author(s)
  Yamaguchi, S., Tatsumi, T.Takehara, T., et al.
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 59 Pages: 759-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590729
[Journal Article] Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet2010
- Author(s)
  Miyagi T, Takehara T(2番目), Tatsumi T(10番目)(他11名)
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1247-1254
- NAID
  10027700169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet2010
- Author(s)
  MIYAGI, T., TAKEHARA, T., UEMURA, A., NISHIO, K., SHIMIZU, S., KODAMA, T., HIKITA, H., LI, W., SASAKAWA, A., TATSUMI, T., OHKAWA, K., KANTO, T., HIRAMATSU, N. & HAYASHI, N.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1247-54
- NAID
  10027700169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590842
[Journal Article] BH3-only protein Bid participates in the Bcl-2 network in healthy liver cells.2010
- Author(s)
  Hikita H, Takehara T, et al.
- Journal Title
  
  Hepatology 50
  
  Pages: 1972-1980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Altered interferon-α-signaling in natural killer cells from patients with chronic hepatitis C virus infection.2010
- Author(s)
  Miyagi T, Takehara T, Kanto T (9番目), 他
- Journal Title
  
  J Hepatol 53
  
  Pages: 424-430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] The Bcl-xL inhihitor, ABT-737.efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.2010
- Author(s)
  Hikita H, Takehara T, et al.
- Journal Title
  
  Hepatology
  
  Volume: 52 Pages: 1310-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Factors affecting efficacy in patients with genotype 2 chronic hepatitis C treated by pegylated interferon alpha-2b and ribavirin: reducing drug doses has no impact on rapid and susutained virological responses.2009
- Author(s)
  Inoue, Y., Hiramatsu, N, Oze, T., Yakushijin, T., Mochizuki, K., Hagiwara, H., Oshita, M., Mita, E., Fukui, H., Inada, M., Tamura, S., Yoshihara, H., Hyashi, E., Inoue, A., Imai, Y., Kato, M., Miyagi, T., Hohsui, A., Ishida, M., Kiso, S., Kanto, T., Kasahara, A., Takehara, T., Hayashi, N.
- Journal Title
  
  Journal of Viral Hepatitis (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma.2009
- Author(s)
  Kohga, K., Takehara, T. Tatsumi, T., Miyagi, T., Ishida, H., Ohkawa, K., Kanto, T., Hiramatsu, N., Hayashi, N.
- Journal Title
  
  Cancer Resarch 69
  
  Pages: 8050-8057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Enhanced ability of regulatory T cells in chronic hepatitis C patients with persistently normal alanine aminotransferase levels than those with active hepatitis.2009
- Author(s)
  Itose, I., Kanto, T. Kakita, N., Takebe, S., Inoue, M., Higashitani, K., Miyazaki, M., Miyatake, H., Sakakibara, M., Hiramatsu, N., Takehara, T., Kasahara, A., Hayashi, N.
- Journal Title
  
  Journal of Viral Hepatitis 16
  
  Pages: 846-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Enhanced ability of regulatory T cells in chronic hepatitis C patients with persistently normal alanine aminotransferase levels than those with active hepatitis.2009
- Author(s)
  Itose I, Kanto T, Takehara T (11番目), 他
- Journal Title
  
  J Viral Hepat 16
  
  Pages: 844-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] BH3-only protein Bid participates in the Bcl-2 network in healthy liver cells2009
- Author(s)
  Hikita H, Takehara T(2番目), Tatsumi T(7番目)(他12名)
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1972-1980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Reduced risk of hepatocellular carcinoma after intetferon therapy in aged patients with chronic hepatitis C is limited to sustained virological responders.2009
- Author(s)
  Imai Y, Takehara T (12番目), 他
- Journal Title
  
  J Viral Hepat 16
  
  Pages: 844-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Activated liver dendritic cells generates strong acquired immunity inα-galactosylceramide treatment2009
- Author(s)
  Sasakawa A, Tatsumi T(2番目), Takehara T(3番目)(他6名)
- Journal Title
  
  J Hepatol
  
  Volume: 50 Pages: 1155-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] BH3-only protein Bid participates in the Bcl-2 network in healthy liver cells2009
- Author(s)
  Hikita H, Takehara T, Kodama T, Shimizu S, Hosui A, Miyagi T, Tatsumi T, Ishida H, Ohkawa K, Li W, Kanto T, Hiramatsu N, Hennighausen L, Yin XM, Hayashi N
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1972-1980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Activated liver dendritic cells generates strong acquired immunity in・-galactosylceramide treatment.2009
- Author(s)
  Sasakawa A, Tatsumi T, Takehara T, Yamaguchi S, Yamamoto M, Ohkawa K, Miyagi T, Hayashi N.
- Journal Title
  
  J Hepatol 50
  
  Pages: 1155-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.2009
- Author(s)
  Hikita H, Takehara T, Kanto T (10番目), 他
- Journal Title
  
  Hepatology 50
  
  Pages: 1009-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Anti-cancer therapy inhibits MICA ectodomain shedding by downregulatine ADAM10 expression in henatocellular carcinoma.2009
- Author(s)
  Kohga K, Takehara T, et al.
- Journal Title
  
  Cancer Res 69
  
  Pages: 8050-8057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Ribavirin dose reduction raises relapse rate dose-dependently in genotype 1 patients with hepatitis C responding to pegylated interferon alpha-2b plus ribavirin.2009
- Author(s)
  Hiramatsu, N., Oze, T Yakushijin, T., Inoue, Y., Igura, T., Mochizuki, K., Imanaka, K., Kaneko, A., Oshita, M., Hagiwara, H., Mita, E., Nagase, T., Ito, T., Inui, Y., Hijioka, T., Katayama, K., Tamura, S., Yoshihara, H., Imai, Y., Kato, M., Yoshida, Y., Tatsumi, T., Ohkawa, K., Kiso, S., Kanto, T., Kasahara, A., Takehara, T., Hayashi, N.
- Journal Title
  
  Journal of Viral Hepatitis 16
  
  Pages: 586-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Natural Killer cell is a major producer of interferon γ that is critical for the IL-12-induced anti-tumor effect in mice.2009
- Author(s)
  Uemura A, Takehara T, 他
- Journal Title
  
  Cancer Immunol Immunother 59
  
  Pages: 453-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Anti-cancer chemotherapy inhibits MICA ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma.2009
- Author(s)
  Kohga K, Takehara T, Kanto T (7番目), 他
- Journal Title
  
  Cancer Res 9
  
  Pages: 8050-8057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma2009
- Author(s)
  Kohga, K., Takehara, T., et al.
- Journal Title
  
  Cancer Resarch 69
  
  Pages: 8050-8057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] BH3-only protein Bid participates in the Bcl-2 network in healthy liver cells.2009
- Author(s)
  Hikita H, Takehara T, Kanto T (11番目), 他
- Journal Title
  
  Hepatology 50
  
  Pages: 1972-1980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Anticancer chemotherapy inhibits MHC Class I-related chain A ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma2009
- Author(s)
  Kohga K, Takehara T(2番目), Tatsuumi T(3番目)(他6名)
- Journal Title
  
  Cancer Res
  
  Volume: 69 Pages: 8050-8057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver2009
- Author(s)
  Hikita H, Takehara T., et al.
- Journal Title
  
  Hepatology 50
  
  Pages: 1217-1226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.2009
- Author(s)
  Hikita H, Takehara T, et al.
- Journal Title
  
  Hepatology 50
  
  Pages: 1217-1226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Anti-cancer therapy inhibits MICA ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma.2009
- Author(s)
  Kohga K, Takehara T, Tatsumi T, Miyagi T, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  Cancer Res 69
  
  Pages: 8050-8057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver2009
- Author(s)
  Hikita H, Takehara T, Shimizu S, Kodama T, Li W, Miyagi T, Hosui A, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Yin XM, Hennighausen L, Tatsumi T, Hayashi N
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1217-1226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659188
[Journal Article] Two types of drug-resistant hepatitis B viral strains emerging alternately and their susceptibility to combination therapy with entecavir and adefovir2009
- Author(s)
  Kurashige N., Ohkawa, K Hiramatsu, N., Oze, T., Yakushijin, T., Mochizuki, K., Hosui, A., Miyagi, T., Ishida, H., Tatsumi, T., Kanto, T., Takehara, T., Hayashi, N.
- Journal Title
  
  Antiviral Therapy 14
  
  Pages: 873-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Activated liver dendritic cells generate strong acquired immunity in alpha-galactosylceramide treatment.2009
- Author(s)
  Sasakawa A, Takehara T (3番目), 他
- Journal Title
  
  J Hepatol 50
  
  Pages: 1155-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.2009
- Author(s)
  Hikita H, Takehara T., Shimizu, S., Kodama, T., Li, W., Miyagi, T., Hosui, A., Ishida, H., Ohkawa, K., Kanto, T., Hiramatsu, N., Yin, X.M., Hennighausen, L., Tatsumi, T., Hayashi, N.
- Journal Title
  
  Hepatology 16
  
  Pages: 1217-1226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult liver2009
- Author(s)
  Hikita H, Takehara T(2番目), Tatsumi T(14番目)(他12名)
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1217-1226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590841
[Journal Article] Dendritic cell-based vaccines suppress metastatic liver tumor via activation of local innate and acquired immunity.2008
- Author(s)
  Yamaguchi S, Tatsumi T, Takehara T, Sasakawa A, Hikita H, Kohga K, Uemura A, Sakamori R, Ohkawa K, Hayashi N.
- Journal Title
  
  Cancer Immunol Immunother 57
  
  Pages: 1861-1869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Early emergence ofentecavir-resistant hepatitis B virusin a patient with hepatitis Bvirus/human immunodeficiency viruscoinfection2008
- Author(s)
  Kanada A, Takehara T(2番目)Tatsumi T(5番目), (他13名)
- Journal Title
  
  Heptol. Res 35
  
  Pages: 622-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Declining incn, from 1990dence of hepatocellular carcinoma in Osaka, Japa0 2003.2008
- Author(s)
  Tanaka H, Takehara T, etal.
- Journal Title
  
  Ann Intern Med 148
  
  Pages: 820-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Supportive role played by precore and preS2 genomic changes in the establishment of lamivudine-resistant hepatitis B virus.2008
- Author(s)
  Ohkawa K., Takehara T., et al.
- Journal Title
  
  Journal of Infectious Diseases 198
  
  Pages: 1150-1158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Innate immunity in type C hepatitis. Hepatitis C virus disease2008
- Author(s)
  Takehara, T., Hayashi, N
- Pages
  1-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Initial viral response is the most powerful predictor of the emergence of YMDD mutant virus in chronic hepatitis B patients treated with lamivudine.2008
- Author(s)
  Kurashige N., Hiramatsu N. Ohkawa, K., Oze, T., Inoue, Y., Kurokawa, M., Yakushijin, T., Igura, T., Kiso, S., Kanto, T., Takehara, T., Tamura, S., Kasahara, A., Oshita, M., Hijioka, T., Katayama, K., Yoshihara, H., Hayashi, E., Imai, Y., Kato, M., Hayashi, N.
- Journal Title
  
  Hepatology Research 38
  
  Pages: 450-456
- NAID
  10024148320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Supportive roleplayed by Precore and PreS2 genomic changes in establishment of Lamivudine-Resitant Hepatitis B virus2008
- Author(s)
  Ohkawa K, Takehara T(2番目), Tatsumi T(14番名), (他12名)
- Journal Title
  
  J. Infect. Dis 198
  
  Pages: 1150-1158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Early emergence of entecavir-resistant hepatitis B virus in a patient with hepatitis B virus/human immunodeficiency virus coinfection2008
- Author(s)
  Kanada, A, Takehara, T, Ohkawa, K, et. al.
- Journal Title
  
  Hepatol Res (in press)
- NAID
  10024149003
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Decreased expressions ofCD1d molecule on liver dendritic cellsin subcutaneous tumor bearing mice2008
- Author(s)
  Tatsumi T(1番目), Takehara T(2番目), (他7名)
- Journal Title
  
  J. Hepatol 49
  
  Pages: 779-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Declining incidence of hepatocellular carcinoma in Osaka, Japan, from 1990 to 2003.2008
- Author(s)
  Tanaka H, Takehara T (13番目), 他
- Journal Title
  
  Ann Intern Med 148
  
  Pages: 820-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virus infection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I.2008
- Author(s)
  Miyazaki M, Kanto T, Takehara T (10番目), 他
- Journal Title
  
  J Med Virol 80
  
  Pages: 980-988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Decreased expressions of CD1d molecule on liver dendritic cells in subcutaneous tumor bearing mice.2008
- Author(s)
  Tatsumi T, Takehara T, 他
- Journal Title
  
  J Hepatol 49
  
  Pages: 779-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Serum levels of soluble major histocompatibility complex (MHC)class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma.2008
- Author(s)
  Kohga K., Takehara T., et al.
- Journal Title
  
  Cancer Science 99
  
  Pages: 1643-1649
- NAID
  10024010054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virusinfection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I2008
- Author(s)
  Miyazaki M., Kanto T., Inoue, M., Itose, I., Miyatake, H., Sakakibara, M., Yakushijin, T., Kakita, N., Hiramatsu, N., Takehara, T., Kasahara, A., Hayashi, N.
- Journal Title
  
  Journal of Medical Virology 80
  
  Pages: 980-988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Decreased expressions of CDld molecule on liver dendritic cells in subcutaneous tuior bearing mice.2008
- Author(s)
  Tatsumi T, Takehara T, et al.
- Journal Title
  
  J Hepatol 49
  
  Pages: 779-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Activated liverdendritic cells generates strongacquired immunity inα-galactosylceramide treatment2008
- Author(s)
  Sasakawa A, Tatsumi T(2番目), Takehara T(3番目), (他5名)
- Journal Title
  
  J. Hepatol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Serum levels of soluble MHC class I-related chain A in patients with chronic liver diseases and the changes during transcatheter arterial embolization for hepatocellular carcinoma.2008
- Author(s)
  Kohga K, Takehara T, Tatsumi T, Ohkawa K, Miyagi T, Hiramatsu N, Kanto T, Kasugai T, Katayama K, Kato M, Hayashi N.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1643-1649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Serum levels ofsoluble major histocompatibilitycomplex (MHC) class I-related chain Ain patients with chronic liverdiseases and changes duringtranscatheter arterial embolizationfor hepatocellular carcinoma2008
- Author(s)
  Kohga K, Takehara T(2番目), TatsumiT(3番目), (他8名)
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1643-1649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Adipocytokines and I iver disease.2008
- Author(s)
  Kaiada Y, Takehara T, etal.
- Journal Title
  
  J Gastroenterol 43
  
  Pages: 811-822
- Data Source
  KAKENHI-PROJECT-19659182
[Journal Article] Serum levels of soluble major histocompatibility complex (MHC) class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma.2008
- Author(s)
  Kohga K, Takehara T, Kanto T (7番目), 他
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1643-1649
- NAID
  10024010054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Decreased expressions of CDld molecule on liver dendritic cells in subcutaneous tumor bearing mice.2008
- Author(s)
  Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Yamamoto M, Fujita Y, Miyagi T, Ohkawa K, Hayashi N.
- Journal Title
  
  J Hepatol 49
  
  Pages: 779-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Serum levels of soluble MHC class I-related chain A in patients with chronic liver diseases and the changes during transcatheter arterial embolization for hepatocellular carcinoma.2008
- Author(s)
  Kohga K, Takehara T, etal.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1643-1649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Early emergence of entecavir-resistant hepatitis B virus in a patient with hepatitis B virus/human immunodeficiency virus coinfection.2008
- Author(s)
  Kanada A, Takehara T, Ohkawa K, et. al.
- Journal Title
  
  Hepatology Research (in press)
- NAID
  10024149003
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Serum levels of soluble major histocompatibility complex (MHC) class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma.2008
- Author(s)
  Kohga K., Takehara T., Tatsumi, T., Ohkawa, K., Miyagi, T., Hiramatsu, N., Kanto, T., Kasugai, T., Katayama, K., Kato, M., Hayashi, N.
- Journal Title
  
  Cancer Science 99
  
  Pages: 1643-1649
- NAID
  10024010054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Mutationsassociated with therapeutic efficacyof Adefovir dipivoxil added toLamivudine-resistant chronichepatitis B2008
- Author(s)
  Ohkawa K, Takehara T(2番目), Tatsumi T(15番目), (他13名))
- Journal Title
  
  J. Med. Virol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Early decline of hemoglobin can predict progression of hemolytic anemia during peglated interferon and ribavirin combination therapy in patients with chronic hepatitis C.2008
- Author(s)
  Hiramatsu N, Takehara T (4番目), 他
- Journal Title
  
  Hepatol Res 38
  
  Pages: 52-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249043
[Journal Article] Dendritic cell-based vaccines suppress livertumor via activation of innate and acquired immunity2008
- Author(s)
  Yamaguchi S, Tatsumi T(2番目), Takehara T(3番目), (他7名)
- Journal Title
  
  Cancer Immunol. Immunother 57
  
  Pages: 1861-1869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Innate immunity in type C hepatitis. Hepatitis C virus disease2008
- Author(s)
  Takehara, T, Hayashi, N
- Pages
  1-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] A new prognostic system for hepatocellular carcinoma including recurrent cases: a study of 861 patients in a single institution.2008
- Author(s)
  Toyama T., Hiramatsu N. Yakushijin, T., Oze, T., Nakanishi, F., Yasumaru, M., Mochizuki, K., Kanto, T., Takehara, T., Kasahara, A., Hayashi, N.
- Journal Title
  
  Journal of Clinical Gastroenterology 42
  
  Pages: 317-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Intrahepatic delivery of α-galactosylceramide-pulsed dendritic cells suppresses liver tumor.2007
- Author(s)
  Tatsumi T, Takehara T, et. al.
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- NAID
  40015716465
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFN alpha gene to mice2007
- Author(s)
  Takehara T., Tatsumi T., et al.
- Journal Title
  
  International Journal of Cancer 120
  
  Pages: 1252-1260
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFN alpha gene to mice2007
- Author(s)
  Takehara, T, Uemura, A, Tatsumi, T, Suzuki, T, Kimura, R, Shiotani, A, Ohkawa, K, et. al.
- Journal Title
  
  Int J Cancer 120
  
  Pages: 1252-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity.2007
- Author(s)
  Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Miyagi T, Jinushi M, Sakamori R, Kouga K, Uemura A, Ohkawa K, Storkus WJ, Hayashi N.
- Journal Title
  
  Gene Ther. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Immunotherapy ofmurine colon cancer using receptortyrosine kinase EphA2 derivedpeptide-pulsed dendritic cellvaccines2007
- Author(s)
  Yamaguchi, Tatsumi T(2番目), Takehara T(3番目), (他7名)
- Journal Title
  
  Cancer 110
  
  Pages: 1469-1477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNalpha gene to mice. Int J Cancer 2007; 120 : 1252-60.2007
- Author(s)
  Takehara T, Uemura A, Tatsumi T, Suzuki T, Kimura R, Shiotani A, Ohkawa K, et al.
- Journal Title
  
  Int J Cancer 120 (6)
  
  Pages: 1252-1260
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Intrahepatic delivery of α-galatosylceramide pulsed dendritic cells suppresses liver tumor.2007
- Author(s)
  Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Sakamori R, Ohkawa K, Kohga K, Uemura A, Hayashi N.
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Natural Killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNα gene to mice.2007
- Author(s)
  Takehara T, Uemura A, et. al.
- Journal Title
  
  International Journal of Cancer 120
  
  Pages: 1252-1260
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice.2007
- Author(s)
  Sakamori R, Takehara T, et. al.
- Journal Title
  
  Hepatology 46
  
  Pages: 1564-1573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659182
[Journal Article] Intrahepatic delivery of α-galactosylceramide-pulsed dendritic cells suppresses liver tumor.2007
- Author(s)
  Tatsumi T, Takehara T, et. al.
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- NAID
  40015716465
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities2007
- Author(s)
  Jinushi, M., Takehara, T., Tatsumi, T., Yamaguchi, S., Sakamori, R., Hiramatsu, N., Kanto, T., Ohkawa, K., Hayashi, N
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Intrahepatic delivery of a-galatosylceramide pulsed dendritic cells suppresses liver tumor2007
- Author(s)
  Tatsumi, T, Takehara, T, Yamaguchi, S, Sasakawa, A, Sakamori, R, Ohkawa, K, et. al.
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Natural Killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4+CD25+ T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi M, Takehara T, Tatsumi T, Yamaguchi S, Sakamori R, Hiramastu N, Kanto T, Ohkawa K, Hayashi N.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi M., Takehara T., et al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Intrahepatic delivery of alpha-galactosylceramide-pulsed dendritic cells suppresses liver tumor2007
- Author(s)
  Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Sakamori R, Ohkawa, K, et. al.
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNalpha gene to mice.2007
- Author(s)
  Takehara T, Uemura A, Tatsumi T, Suzuki T, Kimura R, Shiotani A, Ohkawa K, et. al.
- Journal Title
  
  Int J Cancer 120
  
  Pages: 1252-60
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Intrahepatic delivery of α-galactosylceramide-pulsed dendritic cells suppresses liver tumor2007
- Author(s)
  Tatsumi, T., Takehara, T., Yamaguchi, S., Sasakawa, A., Sakamori, R., Ohkawa, K., Kohga, K., Uemura, A., Hayashi, N
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- NAID
  40015716465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi, M., Takehara, T., et al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNalpha gene to mice.2007
- Author(s)
  Takehara, T., Uemura, A., et al.
- Journal Title
  
  Int J Cancer 120
  
  Pages: 1252-1260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi, M., Takehara, T.et al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNα gene to mice.2007
- Author(s)
  Takehara T, Uemura A, et. al.
- Journal Title
  
  International Journal of Cancer 120
  
  Pages: 1252-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity.2007
- Author(s)
  Tatsumi T, Takehara T, et. al.
- Journal Title
  
  Gene Ther 14
  
  Pages: 863-871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Natural Killer celland hepatic cell interaction via NKG2Aleads to dendritic cell-mediatedinduction of CD4+CD25+ T cells with PD-1-dependent regulatory activities2007
- Author(s)
  Jinushi M, Takehara T(2番目), Tatsumi T(3番目), (他6名)
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Type B fulminant hepatitis is closely associated with a highly mutated hepatitis B virus strain.2007
- Author(s)
  Kanada A, Takehara T, Ohkawa K, et. al.
- Journal Title
  
  Intervirology 50
  
  Pages: 394-401
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4+ CD25+ T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi M, Takehara T, et. al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Intrahepatic delivery of α-galactosylceramide-pulsed dendritic cells suppresses liver tumor2007
- Author(s)
  Tatsumi, T, Takehara, T, Yamaguchi, S, Sasakawa, A, Sakamori, R, Ohkawa, K, Kohga, K, Uemura, A, Hayashi, N
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- NAID
  40015716465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity.2007
- Author(s)
  Tatsumi T, Takehara T, et. al.
- Journal Title
  
  Gene Ther 14
  
  Pages: 863-871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Intrahepatic delivery ofα-galatosylceramide pulsed dendriticcells suppresses liver tumor2007
- Author(s)
  Tatsumi T(1番目), Takehara T(2番目), (他7名)
- Journal Title
  
  Hepatology 45
  
  Pages: 22-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Natural killercell-mediated ablation of metastaticliver tumors by hydrodynamic injectionof IFN alpha gene to mice2007
- Author(s)
  Takehara T(1番目), Tatsumi T(3番目), ( 他8名)
- Journal Title
  
  Int. J. Cancer 120
  
  Pages: 1252-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Type B fulminanthepatitis is closely associated witha highly mutated hepatitis B virusstrain2007
- Author(s)
  Kanada A, Takehara T(2番目), Tatsumi T(4番目), (他14名)
- Journal Title
  
  Intervirology 50
  
  Pages: 294-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNα gene to mice2007
- Author(s)
  Takehara, T., Uemura, A., Tatsumi, T., Suzuki, T., Kimura, R., Shiotani, A., Ohkawa, K., Kanto, T., Hiramatsu, N., Hayashi, N
- Journal Title
  
  Int J Cancer 120
  
  Pages: 1252-1260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities2007
- Author(s)
  Jinushi, M., Takehara, T., et. al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Type B fulminant hepatitis is closely associated with a highly mutated hepatitis B virus strain2007
- Author(s)
  Kanada, A, Takehara, T, Ohkawa, K, et. al.
- Journal Title
  
  Intervirology 50
  
  Pages: 394-401
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNα gene to mice.2007
- Author(s)
  Takehara T, Uemura A, et. al.
- Journal Title
  
  International Journal of Cancer 120
  
  Pages: 1252-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNalpha gene to mice.2007
- Author(s)
  Takehara T.Uemura A., et al.
- Journal Title
  
  International Journal of Cancer 120
  
  Pages: 1252-1260
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4+CD25+ T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi M, Takehara T, et. al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4+ CD25+ T cells with PD-1-dependent regulatory activities2007
- Author(s)
  Jinushi, M., Takehara, T., Tatsumi, T., Yamaguchi, S., Sakamori, R., Hiramatsu, N., Kanto, T., Ohkawa, K., Hayashi, N
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Involvement of dendritic cell frequency and function in virological relapse in pegylated interferon-α2b and ribavirin therapy for chronic hepatitis C patients.2007
- Author(s)
  Itose I., Kanto T., Inoue, M., Miyazaki, M., Miyatake, H., Sakakibara, M., Yakushijin, T., Oze, T., Hiramatsu, N., Takehara, T., Kasahara, A., Hayashi, N.
- Journal Title
  
  Journal of Medical Virology 79
  
  Pages: 511-521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4+ CD25+ T cells with PD-1-dependent regulatory activities.2007
- Author(s)
  Jinushi M, Takehara T, et. al.
- Journal Title
  
  Immunology 120
  
  Pages: 73-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Impaired ability of interferon-alpha-primed dendritic cells to stimulate Th1-type CD4 T cell response in chronic hepatitis C virus infection.2007
- Author(s)
  Miyatake H., Kanto T., Inoue, M., Sakakibara, M., Kaimori, A., Yakushijin, T., Itose, I., Miyazaki, M., Kuzushita, N., Hiramatsu, N., Takehara, T., Kasahara, A., Hayashi, N.
- Journal Title
  
  Journal of Viral Hepatitis 14
  
  Pages: 404-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590765
[Journal Article] Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFN alpha gene to mice2007
- Author(s)
  Takehara T, Uemura A, Tatsumi T, Suzuki T, Kimura R, Shiotani A, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N.
- Journal Title
  
  Int.J.Cancer 120
  
  Pages: 1252-1260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Signal Transducerand Activator of Transcription 3signaling within hepatocytesattenuates systemic inflammatoryresponse and lethality in septic mice2007
- Author(s)
  Sakamori R, Takehara T(2番目), Tatsumi T(4番目), (他5名)
- Journal Title
  
  Hepatology 46
  
  Pages: 1564-1573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Injection of IL-12gene-transduced dendritic cells intomouse liver tumor lesions activatesboth innate and acquired immunity2007
- Author(s)
  Tatsumi T(1番目), Takehara T(2番目), ( 他10名)
- Journal Title
  
  Gene Ther 14
  
  Pages: 863-871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590766
[Journal Article] Intrahepatic delivery of alpha-galactosylceramide-pulsed dendritic cells suppresses liver tumor.2007
- Author(s)
  Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Sakamori R, Ohkawa K, et al.
- Journal Title
  
  Hepatology 45 (1)
  
  Pages: 22-30
- Data Source
  KAKENHI-PROJECT-18599003
[Journal Article] Enhanced ability of peripheral invariant natural killer T cells to produce IL-13 in chronic hepatitis C virus infection.2006
- Author(s)
  Inoue M, Takehara T, et al.
- Journal Title
  
  Journal of Hepatology 45
  
  Pages: 190-196
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Viral covalently closed circular DNA in a non-transgenic mouse model for chronic hepatitis B virus replication.2006
- Author(s)
  Takehara T, Suzuki T, Ohkawa K, Housui A, Jinushi M, Miyagi T, Tatsumi T, Kanazawa Y, Hayashi N.
- Journal Title
  
  Journal of Hepatology 44
  
  Pages: 267-274
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Quick generation of fully mature dendritic cells from monocytes with OK432, low-doseprostanoid and interferon-α as potent immune enhancers.2006
- Author(s)
  Sakakibara M, Takehara T, et al.
- Journal Title
  
  Journal of Immunotherapy 29
  
  Pages: 67-77
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Viral covalently closed circular DNA in a non-transgenic mouse model for chronic hepatitis B virus replication.2006
- Author(s)
  Takehara T, Suzuki T, et al.
- Journal Title
  
  Journal of Hepatology 44
  
  Pages: 267-274
- Data Source
  KAKENHI-PROJECT-17659214
[Journal Article] Reduced expression and functional impairment of Toll-like receptor 2 on dendritic cells in chronic hepatitis C virus infection.2006
- Author(s)
  Yakushijin T, Takehara T, et al.
- Journal Title
  
  Hepatology Research 35
  
  Pages: 185-189
- NAID
  10020405278
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Viral covalently closed circular DNA in a non-transgenic mouse model for chronic hepatitis B virus replication2006
- Author(s)
  Takehara T., Tatsumi T., et al.
- Journal Title
  
  Journal of Hepatology 44
  
  Pages: 267-274
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Should aged patients with chronic hepatitis C be treated with interferon and ribavirin combination therapy?2006
- Author(s)
  Hiramatsu N, Takehara T, et al.
- Journal Title
  
  Hepatology Research 35
  
  Pages: 185-189
- NAID
  10018774942
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Early decline of hemoglobin correlates with progression of ribavirin-induced hemolytic anemia during interferon plus ribavirin combination therapy in patients with chronic hepatitis C.2006
- Author(s)
  Oze T, Takehara T, et al.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 862-872
- NAID
  10020626268
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Quick generation of fully mature dendritic cells from monocytes with OK432, low-doseprostanoid and interferon-α as potent immune enhancers.2006
- Author(s)
  Sakakibara M, Takehara T, et al.
- Journal Title
  
  Journal of Immunotherapy 29
  
  Pages: 67-77
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Suppressive effect on hepatocyte differentiation of hepatitis C virus core protein.2006
- Author(s)
  Hosui A, Takehara T, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 346
  
  Pages: 1125-1130
- Data Source
  KAKENHI-PROJECT-18390216
[Journal Article] Suppressive effect on hepatocyte differentiation of hepatitis C virus core protein.2006
- Author(s)
  Hosui A., Takehara T., et al.
- Journal Title
  
  Biochem Biophys Res Commun 346
  
  Pages: 1125-1130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Anti-viral therapy for chronic hepatitis C : past, present, and future.2006
- Author(s)
  Hayashi N, Takehara T.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Suppressive effect on hepatocyte differentiation of hepatitis C virus core protein.2006
- Author(s)
  Hosui, A., Takehara, T., et al.
- Journal Title
  
  Biochem Biophys Res Comm un 346
  
  Pages: 1125-1130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Anti-viral therapy for chronic hepatitis C : past, present, and future.2006
- Author(s)
  Hayashi N, Takehara T.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-17659214
[Journal Article] Anti-viral therapy for chronic hepatitis C : past, present, and future.2006
- Author(s)
  Hayashi N, Takehara T.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Quick generation of fully mature dendritic cells from monocytes with OK432, low-doseprostanoid and interferon-α as potent immune enhancers.2006
- Author(s)
  Sakakibara M, Takehara T, et al.
- Journal Title
  
  Journal of Immunotherapy 29
  
  Pages: 67-77
- Data Source
  KAKENHI-PROJECT-17659214
[Journal Article] Suppressive effect on hepatocyte differentiation of hepatitis C virus core protein.2006
- Author(s)
  Hosui, A., Takehara, T., et al.
- Journal Title
  
  Biochemistry and Biophysics Research Communications 346
  
  Pages: 1125-1130
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Viral covalently closed circular DNA in a non-transgenic mouse model for chronic hepatitis B virus replication.2006
- Author(s)
  Takehara T, Suzuki T, et al.
- Journal Title
  
  Journal of Hepatology 44
  
  Pages: 267-274
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Quick generation of fully mature dendritic cells from monocytes with OK432, low-doseprostanoid and interferon-α as potent immune enhancers.2006
- Author(s)
  Sakakibara M, Takehara T, et al.
- Journal Title
  
  Journal of Immunotherapy 29
  
  Pages: 67-77
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Viral covalently closed circular DNA in a non-transgenic mouse model for chronic hepatitis B virus replication.2006
- Author(s)
  Takehara T, Suzuki T, et al.
- Journal Title
  
  Journal of Hepatology 44
  
  Pages: 267-274
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.2005
- Author(s)
  Jinushi M, Takehara T, et al.
- Journal Title
  
  Journal of Hepatology 43
  
  Pages: 1013-1020
- Data Source
  KAKENHI-PROJECT-17659214
[Journal Article] Alteration in gene expression profile by full-length hepatitis B virus genome.2005
- Author(s)
  Nakanishi F, Takehara T, et al.
- Journal Title
  
  Intervirology 48
  
  Pages: 77-83
- Data Source
  KAKENHI-PROJECT-17659214
[Journal Article] Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinoma.2005
- Author(s)
  Jinushi M, Takehara T, Tatsumi T, Hiramatsu N, Sakamori R, Yamaguchi S, Hayashi N.
- Journal Title
  
  J.Hepatol. 43
  
  Pages: 1013-1020
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590638
[Journal Article] Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.2005
- Author(s)
  Jinushi M., Takehara T., et al.
- Journal Title
  
  Journal of Hepatology 43
  
  Pages: 1013-1020
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Alteration in gene expression profile by full-length hepatitis B virus genome.2005
- Author(s)
  Nakanishi F, Takehara T, et al.
- Journal Title
  
  Intervirology 48
  
  Pages: 77-83
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.2005
- Author(s)
  Jinushi M, Takehara T, Tatsumi T, Hiramatsu N, Sakamori R, Yamaguchi S, Hayashi N.
- Journal Title
  
  Journal of Hepatology 43
  
  Pages: 1013-1020
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.2005
- Author(s)
  Jinushi M, Takehara T, et al.
- Journal Title
  
  Journal of Hepatology 43
  
  Pages: 1013-1020
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Alteration in gene expression profile by full-length hepatitis B virus genome.2005
- Author(s)
  Nakanishi F, Takehara T, et al.
- Journal Title
  
  Intervirology 48
  
  Pages: 77-83
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Natural killer cells in hepatitis C virus infection : from innate immunity to adaptive immunity.2005
- Author(s)
  Takehara T, Hayashi N.
- Journal Title
  
  Clinical Gastroenterology and Hepatology 3
- Data Source
  KAKENHI-PROJECT-17659214
[Journal Article] Natural killer cells in hepatitis C virus infection : from innate immunity to adaptive immunity2005
- Author(s)
  Takehara T, Hayashi N.
- Journal Title
  
  Clinical Gastroenterology and Hepatology 3
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Natural killer cells in hepatitis C virus infection : from innate immunity to adaptive immunity.2005
- Author(s)
  Takehara T, Hayashi N.
- Journal Title
  
  Clinical Gastroenterology and Hepatology 3
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.2005
- Author(s)
  Jinushi M, Takehara T, et al.
- Journal Title
  
  Journal of Hepatology 43
  
  Pages: 1013-1020
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Natural killer cells in hepatitis C virus infection : from innate immunity to adaptive immunity.2005
- Author(s)
  Takehara T, Hayashi N.
- Journal Title
  
  Clinical Gastroenterology and Hepatology 3
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection2004
- Author(s)
  Kanto, T, Inoue, M, Miyatake, H, Sato, A, Sakakibara, M, Yakushijin, T, Oki, C, Itose, I, Hiramatsu, N, Takehara, T, Kasahara, A, Hayashi, N
- Journal Title
  
  J Infect Dis 190
  
  Pages: 1919-1926
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.2004
- Author(s)
  Takehara T, et al.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 1189-1197
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.2004
- Author(s)
  Takehara T, et al.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 1189-1197
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Concanavarin A injection activates intrahepatic innate immune cells to provoke an anti-tumor effect in murine liver.2004
- Author(s)
  Miyagi T, Takehara T, et al.
- Journal Title
  
  Hepatology 40
  
  Pages: 1190-1196
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.2004
- Author(s)
  Jinushi M, Takehara T, Tatsumi T, Kanto T, Miyagi T, Suzuki T, Kanazawa Y, Hiramatsu N, Hayashi N.
- Journal Title
  
  Journal of Immunology 173
  
  Pages: 6072-6081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Concanavarin A injection activates intrahepatic innate immune cells to provoke an anti-tumor effect in murine liver.2004
- Author(s)
  Miyagi T, Takehara T, Tatsumi T, Suzuki T, Jinushi M, Kanazawa Y, Hiramatsu N, Kanto T, Tsuji S, Hori M, Hayashi N.
- Journal Title
  
  Hepatology 40
  
  Pages: 1190-1196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.2004
- Author(s)
  Takehara T, Tatsumi T, Suzuki T, Rucker III EB, Hennighausen L, Jinushi M, Miyagi T, Kanazawa Y, Hayashi N.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 1189-1197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions ・・・・2004
- Author(s)
  Jinushi, M., Takehara, T., et al.
- Journal Title
  
  Journal of Immunology 173
  
  Pages: 6072-6081
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.2004
- Author(s)
  Jinushi M., Takehara T., et al.
- Journal Title
  
  Journal of Immunology 173
  
  Pages: 6072-6081
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.2004
- Author(s)
  Jinushi M, Takehara T, Tatsumi T, Kanto T, Miyagi T, Suzuki T, Kanazawa Y, Hiramatsu N, Hayashi N.
- Journal Title
  
  J Immunol 173
  
  Pages: 6072-6081
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver.2004
- Author(s)
  Miyagi T., Takehara T., et al.
- Journal Title
  
  Hepatology 40
  
  Pages: 1190-1196
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.2004
- Author(s)
  Takehara, T., Tatsumi, T., et al.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 1189-1197
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.2004
- Author(s)
  Takehara T, Tatsumi T, et al.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 1189-1197
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.2004
- Author(s)
  Jinushi, M., Takehara, T., et al.
- Journal Title
  
  J Immunol 173
  
  Pages: 6072-6081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.2004
- Author(s)
  Jinushi M, Takehara T, et al.
- Journal Title
  
  Journal of Immunology 173
  
  Pages: 6072-6081
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390207
[Journal Article] Hepatitis C virus core functions as a suppressor of cyclin-dependent kinase-activating kinase and impairs cell cycle progression.2004
- Author(s)
  Ohkawa K, Ishida H, Nakanishi F, Hosui A, Ueda K, Takehara T, Hori M, Hayashi N.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 11719-11726
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver.2004
- Author(s)
  Miyagi, T., Takehara, T., et al.
- Journal Title
  
  Hepatology 40
  
  Pages: 1190-1196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590592
[Journal Article] Critical role of MHC class I-related chain A and B expression on interferon α-stimulated dendritic cells in NK cell activation : Impairment in chronic hepatitis C virus infection2003
- Author(s)
  Jinushi, M, Takehara, T., Kanto, T., Tatsumi, T, Groh, V, Spies, T, Miyagi, T, Suzuki, T, Sasaki, Y, Hayashi, N
- Journal Title
  
  J Immunol 170
  
  Pages: 1249-1256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Critical role of MHC class I-related chain A and B expression on interferon α-stimulated dendritic cells in NK cell activation: Impairment in chronic hepatitis C virus infection.2003
- Author(s)
  Jinushi M, Takehara T, et. al.
- Journal Title
  
  Journal of Immunology 170
  
  Pages: 1249-1256
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109006
[Journal Article] Peyer's Patches Play a Protective Role in Nonsteroidal Anti-inflammatory Drug-induced Enteropathy in Mice
- Author(s)
  Hiyama S, Iijima H, Tsujii M, Takehara T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24651581
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease
- Author(s)
  Mukai A, Iijima H, H, Nishida T, Tsujii M, Takehara T.
- Journal Title
  
  J Gastroenterol
  
  Volume: (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24356810
- Data Source
  KAKENHI-PROJECT-24659365
[Journal Article] Differential alteration of CD56-bright and CD56-dim NK cells in frequency, phenotype and cytokine response in patients with chronic hepatitis C virus infection.
- Author(s)
  Miyagi T, Shimizu S, Nishio K, Tatsumi T, Hiramatsu N, Kanto T, Hayashi N, Takehara T.
- Journal Title
  
  J Gastroenterol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Journal Article] Fibroblast growth factor-2 enhances NK sensitivity of hepatocellular carcinoma cells.
- Author(s)
  Tsunematsu H, Tatsumi T, Kohga K, Yamamoto M, Aketa H, Miyagi T, Hosui A, Hiramatsu N, Kanto T, Hayashi N, Takehara T.
- Journal Title
  
  Int J Cancer in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Activation of hepatocyte p53 triggers acute liver failure with multiple organ injury.2023
- Author(s)
  Jihyun Sung, Hayato Hikita, Yuki Makino, Seiya Kato, Yoichi Sasaki, Kenji Fukumoto, Kazuhiro Murai, Kunimaro Furuta, Akira Nishio, Takahiro Kodama, Tomohide Tatsumi and Tetsuo Takehara
- Organizer
  AASLD2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] 炎症制御分子 Regnase-1 を介した膵がん発症・進展機構の解明2023
- Author(s)
  岡部純弥、小玉尚宏、竹原　徹郎
- Organizer
  第54回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-22K19527
[Presentation] 肝細胞のP53活性化による肝発癌促進機構2022
- Author(s)
  疋田隼人、牧野祐紀、竹原徹郎
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] Sustained hepatocyte p53 activation induces non-cell autonomous liver carcinogenesis2022
- Author(s)
  Hayato Hikita, Yuki Makino, Kenji Fukumoto, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  APASL Oncology 2022 in Takamatsu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] Activation of tumor suppressor p53 in hepatocytes paradoxically promotes liver carcinogenesis derived from hepatic progenitor cells.2021
- Author(s)
  Yuki Makino, Hayato Hikita, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  SH International Liver Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] 慢性肝疾患における肝細胞のp53活性化による肝前駆細胞の出現と肝発癌2021
- Author(s)
  牧野祐紀　疋田隼人　竹原徹郎
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] CTGF is an intercellular mediator to stimulate hepatic stellate cells and promote hepatic fibrosis2021
- Author(s)
  Yuki Makino Hayato Hikita Tetsuo Takehara
- Organizer
  第29回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] 肝類洞内皮細胞が産生する CTGF による肝星細胞の活性化と線維化進展2021
- Author(s)
  佐々木陽一、疋田隼人、牧野祐紀、小玉尚宏、阪森亮太郎、巽智秀、竹原徹郎
- Organizer
  第35回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] Constitutive activation of hepatocyte p53 paradoxically promotes liver carcinogenesis derived from hepatic progenitor cells2021
- Author(s)
  Yuki Makino, Hayato Hikita, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02903
[Presentation] 炎症制御分子Regnase-1を介した膵癌発症機構の解明2020
- Author(s)
  岡部純弥、小玉尚宏、竹原徹郎
- Organizer
  JDDW2020
- Data Source
  KAKENHI-PROJECT-18K19546
[Presentation] アダプター蛋白Gab1は肝細胞アポトーシス・肝線維化・肝発癌を抑制する2020
- Author(s)
  水谷直揮、疋田隼人、齋藤義修、吉田雄一、小玉尚宏、阪森亮太郎、巽智秀、竹原徹郎
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 肝癌微小環境における肝星細胞のオートファジーを介したGDF15の意義2020
- Author(s)
  明神悠太、疋田隼人、竹原徹郎
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 膵多血性腫瘍に対するEUS-FNAの工夫2020
- Author(s)
  清田良介、重川　稔、吉岡鉄平、竹原徹郎
- Organizer
  第105回日本内視鏡学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-18K19546
[Presentation] Hepatic stellate cell autophagy promotes HCC progression via GDF152020
- Author(s)
  Yuta Myojin, Hayato Hikita, Masaya Sugiyama, Takahiro Kodama, Yuki Makino, Ryoko Yamada, Tasuku Nakabori, Ryotaro Sakamori, Tomohide Tatsumi, Masashi Mizokami, Tetsuo Takehara
- Organizer
  The Digital International Liver Congress of the European Association for the Study of the Liver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] GDF15 secreted by hepatic stellate cells accelerates HCC progression in an autophagy-dependent manner2020
- Author(s)
  Yuta Myojin, Hayato Hikita , Masaya Sugiyama, Takahiro Kodama, Yuki Makino, Ryoko Yamada, Ryotaro Sakamori, Tomohide Tatsumi, Masashi Mizokami, Tetsuo Takehara
- Organizer
  The Liver Meeting Digital Experience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 長期経過観察例からみる自己免疫性膵炎の課題2020
- Author(s)
  重川　稔、吉岡鉄平、竹原徹郎
- Organizer
  第51回日本膵臓学会
- Data Source
  KAKENHI-PROJECT-18K19546
[Presentation] 肝星細胞がオートファジー依存的に分泌するGDF15は肝細胞癌の進展に寄与する2020
- Author(s)
  明神悠太、疋田隼人、小玉尚宏、牧野祐紀、阪森亮太郎、巽智秀、溝上雅史、江口英利、竹原徹郎
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 慢性膵炎におけるHippo/PI3K経路の調節不全と治療標的としての可能性2020
- Author(s)
  田村猛、小玉尚宏、吉岡鉄平、重川稔、疋田隼人、阪森亮太郎、秋田裕史、江口英利、巽智秀、竹原徹郎
- Organizer
  第51回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-18K19546
[Presentation] THE RELATIONSHIP BETWEEN OBSERVATION INTERVAL AND PROGNOSIS IN PANCREATIC CANCER ASSOCIATED WITH PANCREATIC CYSTIC LESIONS2019
- Author(s)
  Teppei Yoshioka, Minoru Shigekawa, Yu Sato, Junya Okabe, Takeshi Tamura, Katsuhiko Sato, Makiko Urabe, Takuo Yamai, Takahiro Suda, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi and Tetsuo Takehara
- Organizer
  Digestive Disease Week (DDW2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19546
[Presentation] 肝癌発育進展における肝星細胞オートファジーの意義2019
- Author(s)
  明神悠太、疋田隼人、竹原徹郎
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] The autophagy in hepatic stellate cell promotes carcinogenesis and fibrosis in liver via IL6-STAT3 pathway2019
- Author(s)
  Yuta Myojin, Hayato Hikita ,Takahiro Kodama, Yuki Makino, Ryoko Yamada, Tasuku Nakabori, Ryotaro Sakamori, Tomohide Tatsumi,Tetsuo Takehara
- Organizer
  The Liver Meeting 2019 (AASLD2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] がん特異的アミノ酸トランスポータを標的とした膵癌治療の可能性2019
- Author(s)
  野崎　泰俊、疋田　隼人、竹原　徹郎
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K19546
[Presentation] 持続的肝細胞アポトーシスは、酸化ストレス依存的にジエチルニトロサミンによるDNA損傷を持続させ腫瘍形成を促進させる2019
- Author(s)
  野﨑泰俊、疋田隼人、田中聡司、水谷直揮、明神悠太、坂根貞嗣、牧野祐紀、中堀輔、齋藤義修、小玉尚宏、阪森亮太郎、巽智秀、竹原徹郎
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 転写因子FoxM1を標的とした新規NASH治療法の可能性について2019
- Author(s)
  倉橋知英、吉田雄一、竹原徹郎
- Organizer
  第23回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 肝星細胞のオートファジーがNASH肝癌の発育進展に与える影響の検討2019
- Author(s)
  明神悠太、疋田隼人、竹原徹郎
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 肝癌微小環境における肝星細胞の影響2019
- Author(s)
  疋田隼人、明神悠太、牧野祐紀、小玉尚宏、竹原徹郎
- Organizer
  第33回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 慢性肝疾患におけるマクロファージ由来TNF-αは肝細胞における非アポトーシス型の肝細胞死誘導と酸化ストレス誘導により肝発癌を促進する2019
- Author(s)
  齋藤　義修，疋田　隼人，工藤　慎之輔，野崎　泰俊，牧野　祐紀，中堀　輔，山田涼子，小玉　尚宏，阪森　亮太郎，巽　智秀，竹原　徹郎
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] HCC promotes autophagy in hepatic stellate cells, leading to HCC progression via IL-6/STAT3 signaling2019
- Author(s)
  Yuta Myojin, Hayato Hikita ,Takahiro Kodama, Yuki Makino, Ryoko Yamada, Yoshinobu Saito, Tasuku Nakabori, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 54rd International Liver Congress of the European Association for the Study of the Liver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 肝細胞アポトーシスに起因する慢性肝疾患におけるTNF-αの役割についての検討2018
- Author(s)
  齋藤　義修，疋田　隼人，甲斐　優吾，野崎　泰俊，牧野　祐紀，中堀　輔，小玉　尚宏，阪森　亮太郎，巽　智秀，竹原　徹郎
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] DNase II Activated by the mitochondrial apoptotic pathway regulates RIP-1 dependent hepatocyte non-apoptotic cell death via the TLR9/IFN-β signaling pathway.2018
- Author(s)
  Yoshinobu Saito, Hayato Hikita, Tetsuo Takehara
- Organizer
  Australia-Japan Meeting on Cell Death
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Presentation] 慢性肝疾患においてTNF-αが肝細胞死に及ぼす影響についての検討2018
- Author(s)
  齋藤　義修，疋田　隼人，野崎　泰俊，牧野　祐紀，中堀　輔，小玉　尚宏，阪森　亮太郎，巽　智秀，竹原　徹郎
- Organizer
  第25回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] Persistent hepatocyte apoptosis accelerates diethylnitrosamine(DEN)-induced liver tumor formation2018
- Author(s)
  Yasutoshi Nozaki, Hayato Hikita, Satoshi Tanaka, Yuta Myojin, Yuki Makino, Yoshinobu Saito, Takahiro Kodama, RYotaro Sakamori, Tomohide Tatsumi and Tetsuo Takehara
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 肝細胞DNase IIはアポトーシス刺激下においてTLR9/IFN-β経路を介した非アポトーシス細胞死を制御する2018
- Author(s)
  齋藤　義修，疋田　隼人，甲斐　優吾，野崎　泰俊，牧野　祐紀，中堀　輔，小玉　尚宏，阪森　亮太郎，巽　智秀，竹原　徹郎
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Presentation] Continuous hepatocyte apoptosis accelerates diethylnitrosamine-induced liver tumor development via oxidative stress2018
- Author(s)
  Yasutoshi Nozaki, Hayato Hikita, Satoshi Tanaka, Naoki Mizutani, Sadatsugu Sakane,　Yuki Makino, Tasuku Nakabori, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  AASLD 2018　The Liver meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] The impact of TNF-α-induced non-apoptotic cell death on hepatocarcinogenesis related with continuous hepatocyte apoptosis2018
- Author(s)
  Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, Yuki Makino, Tasuku Nakabori, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  AASLD 2018　The Liver meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] The impact of TNF-α on hepatocarcinogenesis related with continuous hepatocyte apoptosis2018
- Author(s)
  Yoshinobu Saito, Hayato Hikita, Yuta Myojin, Yasutoshi Nozaki, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02795
[Presentation] 高脂肪食による脂肪組織のオートファジーの亢進が肝脂肪蓄積を増悪させる2017
- Author(s)
  坂根貞嗣、疋田隼人、竹原徹郎
- Organizer
  第42回日本肝臓学会西部会
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Presentation] 肝細胞DNaseⅡ活性の低下は、肝細胞ネクローシスを誘導し非アルコール性肝疾患の病態進展に寄与する2017
- Author(s)
  疋田　隼人，齋藤　義修，竹原　徹郎
- Organizer
  第26回日本Ceｌｌ Death学会学術集会
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Presentation] 高脂肪食による脂肪組織のオートファジーの亢進が肝脂肪蓄積を増悪させる2017
- Author(s)
  坂根貞嗣、疋田隼人、竹原徹郎
- Organizer
  第42回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Autophagic changes of both adipose tissues and the liver induced by high fat diet feeding contribute to hepatic lipid accumulation2017
- Author(s)
  Sadatsugu Sakane, Hayato Hikita, Satoshi Tanaka, Kumiko Shirai, Naoki Mizutani, Yuta Myojin, Yuto Shiode, Yasutoshi Nozaki, Yoshinobu Saito, Tasuku Nakabori, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  AASLD The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] NAFLDの病態における肝細胞DNaseIIの役割2017
- Author(s)
  齋藤　義修，疋田　隼人，甲斐　優吾，野崎　泰俊，牧野　祐紀，中堀　輔，田中　聡司，小玉　尚宏，阪森　亮太郎，巽　智秀，竹原　徹郎
- Organizer
  第59回日本消化器病学会
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Presentation] 肝臓と脂肪組織のオートファジーによる肝脂肪蓄積制御2017
- Author(s)
  坂根貞嗣、疋田　隼人、田中　聡司、明神　悠太、塩出　悠登、野崎　泰俊、齋藤　義修、中堀　輔、小玉　尚宏、阪森　亮太郎、巽　智秀、竹原　徹郎
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Presentation] Autophagic changes of both adipose tissues and the liver induced by high fat diet feeding contribute to hepatic lipid accumulation2017
- Author(s)
  Sadatsugu Sakane, Hayato Hikita, Satoshi Tanaka, Kumiko Shirai, Naoki Mizutani, Yuta Myojin, Yuto Shiode, Yasutoshi Nozaki, Yoshinobu Saito, Tasuku Nakabori, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  AASLD The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Presentation] 肝臓と脂肪組織のオートファジーによる脂肪蓄積制御2017
- Author(s)
  坂根貞嗣、疋田　隼人、田中　聡司、明神　悠太、塩出　悠登、野崎　泰俊、齋藤　義修、中堀　輔、小玉　尚弘、阪森　亮太郎、巽　智秀、竹原　徹郎
- Organizer
  第1回消化器臓器間ネットワーク研究会
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Intake of high fat diet causes suppression of hepatocyte autophagy and enhancement of adipocyte autophagy and controls fat deposition of liver and adipose tissue2017
- Author(s)
  Sadatsugu Sakane, Hayato Hikita, Satoshi Tanaka, Yasutoshi Nozaki, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tsuyoshi Kawabata, Maho Hamasaki, Tamotsu Yoshimori, Tetsuo Takehara
- Organizer
  The 8th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Suppression of DNase II activity in fatty livers contributes to induction of RIP1-dependent hepatocyte necrosis through TLR9-IFNβ pathway.2017
- Author(s)
  Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, Yugo Kai, Yuki Makino, Tasuku Nakabori, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  AASLD 2017　The Liver meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Presentation] 肝臓と脂肪組織のオートファジーによる肝脂肪蓄積制御2017
- Author(s)
  坂根貞嗣、疋田　隼人、田中　聡司、明神　悠太、塩出　悠登、野崎　泰俊、齋藤　義修、中堀　輔、小玉　尚宏、阪森　亮太郎、巽　智秀、竹原　徹郎
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Intake of high fat diet causes suppression of hepatocyte autophagy and enhancement of adipocyte autophagy and controls fat deposition of liver and adipose tissue2017
- Author(s)
  Sadatsugu Sakane, Hayato Hikita, Satoshi Tanaka, Yasutoshi Nozaki, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tsuyoshi Kawabata, Maho Hamasaki, Tamotsu Yoshimori, Tetsuo Takehara
- Organizer
  The 8th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Presentation] DNA分解酵素DNase IIの活性低下による脂肪性肝疾患の病態進展2017
- Author(s)
  齋藤　義修，疋田　隼人，竹原　徹郎
- Organizer
  第54回日本肝臓学会大会
- Data Source
  KAKENHI-PUBLICLY-17H05508
[Presentation] Significance of the up-regulation of connective tissue growth factor in hepatocellular carcinoma2016
- Author(s)
  Yuki Makino, Hayato Hikita, Takahiro Kodama, Minoru Shigekawa, Tasuku Nakabori, Yoshinobu Saito, Satoshi Tanaka, Ryotaro Sakamori, Tomohide Tatsumi, and Tetsuo Takehara
- Organizer
  The 25th Conference of the Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] Autophagy Impairment in Pancreatic Acinar Cells Induces Accuulation of Zymogen Granules2016
- Author(s)
  Kiyoshi Iwahashi, Hayato Hikita, Minoru Shigekawa, Kenji Ikezawa, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego
- Year and Date
  2016-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15429
[Presentation] 肝細胞と脂肪細胞におけるRubiconを介した脂肪代謝の制御2016
- Author(s)
  坂根貞嗣　竹原徹郎
- Organizer
  第10回オートファジー研究会
- Place of Presentation
  新潟
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Presentation] 肝細胞と脂肪細胞におけるRubiconを介した脂肪代謝の制御2016
- Author(s)
  坂根貞嗣　竹原徹郎
- Organizer
  第10回オートファジー研究会
- Place of Presentation
  新潟
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] 脂肪酸負荷は、肝細胞Rubiconの分解遅延によりオートファジーを抑制することで、脂肪滴蓄積と肝細胞障害を増悪させる2016
- Author(s)
  田中　聡司、　疋田　隼人、竹原　徹郎
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] 脂肪酸負荷は、肝細胞Rubiconの分解遅延によりオートファジーを抑制することで、脂肪滴蓄積と肝細胞障害を増悪させる2016
- Author(s)
  田中　聡司、　疋田　隼人、竹原　徹郎
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PUBLICLY-16H01204
[Presentation] ３D内視鏡システムを用いた消化管病変の大きさ測定2015
- Author(s)
  辻井正彦、渡部健二、吉本佳代子、飯島英樹、加藤元彦、西田勉、林　義人、竹原徹郎
- Organizer
  日本消化器内視鏡学会
- Place of Presentation
  名古屋
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K15292
[Presentation] 肝細胞への脂肪酸負荷はRubicon発現増加を介してオートファジーを抑制し、肝障害を増悪させる。2015
- Author(s)
  田中　聡司、疋田　隼人、竹原　徹郎
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Significance of connective tissue growth factor in hepatocellular carcinoma and its potential for therapeutic target2015
- Author(s)
  Yuki Makino, Hayato Hikita, Tsukasa Kawaguchi, Takahiro Kodama, Minoru Shigekawa, Yugo Kai, Yasutoshi Nozaki, Tasuku Nakabori, Yoshinobu Saito, Satoshi Tanaka, Ryotaro Sakamori, Takuya Miyagi, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 66th Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] Significance of connective tissue growth factor in hepatocellular carcinoma2015
- Author(s)
  Yuki Makino, Hayato Hikita, Tsukasa Kawaguchi, Takahiro Kodama, Minoru Shigekawa, Yugo Kai, Yasutoshi Nozaki, Tasuku Nakabori, Yoshinobu Saito, Satoshi Tanaka, Ryotaro Sakamori, Takuya Miyagi, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 3rd JSGE International Topic Conference
- Place of Presentation
  Sendai, Japan
- Year and Date
  2015-04-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] Enhanced expression of Rubicon inhibits autophagy and promotes apoptosis by increasing endoplasmic reticulum stress in nonalcoholic fatty liver disease.2015
- Author(s)
  Satoshi Tanaka, Hayato Hikita, Sadatsugu Sakane, Yasutoshi Nozaki, Yugo Kai, Tasuku Nakabori, Yoshinobu Saito, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 66th Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] 肝細胞癌におけるRas経路とCTGFの意義・新規治療標的としての可能性2015
- Author(s)
  牧野祐紀　疋田隼人　川口司　甲斐優吾　野崎泰俊　中堀輔　齋藤義修　田中聡司　重川稔　小玉尚宏　阪森亮太郎　宮城琢也　巽智秀　竹原徹郎
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] Significance of connective tissue growth factor with the malignant grade of hepatocellular carcinoma and its potential for therapeutic target2015
- Author(s)
  Yuki Makino, Hayato Hikita, and Tetsuo Takehara
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] 非アルコール性脂肪肝炎病態形成における、オートファジー制御蛋白Rubiconの役割2015
- Author(s)
  田中　聡司、疋田　隼人、野崎　泰俊、甲斐　優吾、牧野　祐紀、中堀　輔、齋藤　義修、阪森　亮太郎、巽　智秀、竹原　徹郎
- Organizer
  第22回肝細胞研究会
- Place of Presentation
  米子
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] NASH病態形成におけるRubicon発現増加を介したオートファジー抑制と小胞体ストレス応答の活性化2015
- Author(s)
  田中聡司、　疋田隼人、　竹原徹郎
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Enhanced expression of Rubicon inhibits autophagy and promotes apoptosis by increasing endoplasmic reticulum stress in nonalcoholic fatty liver disease2015
- Author(s)
  Satoshi Tanaka, Hayato Hikita, Tetsuo Takehara
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Role of connective tissue growth factor in hepatocellular carcinoma2015
- Author(s)
  Yuki Makino, Hayato Hikita, Yasutoshi Nozaki, Kenji Ikezawa, Yoshinobu Saito, Satoshi Tanaka, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  日本癌学会第74回総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] バレット腺癌に対するESD治療成績2014
- Author(s)
  林　義人、辻井正彦、竹原徹郎
- Organizer
  日本内視鏡学会近畿支部例会
- Place of Presentation
  大阪
- Year and Date
  2014-06-22
- Data Source
  KAKENHI-PROJECT-24390188
[Presentation] NASH病態形成におけるオートファジーとアポトーシスの意義2014
- Author(s)
  田中聡司、　疋田隼人、　牧野祐紀、　中堀輔、　齋藤義修、　阪森亮太郎、宮城琢也、　巽智秀、　竹原徹郎
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] 肝発癌・進展におけるRas経路の活性化とCTGF2014
- Author(s)
  牧野祐紀　疋田隼人　竹原徹郎
- Organizer
  第18回日本肝臓学会大会（JDDW2014）
- Place of Presentation
  神戸
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] NASH病態形成におけるオートファジーとアポトーシスの意義2014
- Author(s)
  田中　聡司、疋田　隼人、竹原　徹郎
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Significance of connective tissue growth factor (CTGF) for the oncogenesis and progression of hepatocellular carcinoma2014
- Author(s)
  Yuki Makino, Hayato Hikita, Tsukasa Kawaguchi, Yugo Kai, Yasutoshi Nozaki, Tasuku Nakabori, Yoshinobu Saito, Satoshi Tanaka, Ryotaro Sakamori, Takuya Miyagi, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  日本癌学会第73回総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] Increased expression of Rubicon protein by high fat diet suppresses autophagic flux and induces apoptosis by increasing endoplasmic reticulum stress in the pathogenesis of non-alcoholic fatty liver disease2014
- Author(s)
  Satoshi Tanaka, Hayato Hikita, Yasutoshi Nozaki, Yugo Kai, Tasuku Nakabori, Yoshinobu Saito, Ryotaro Sakamori, Takuya Miyagi, Naoki Hiramatsu, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 65th Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] 脂肪肝炎におけるオートファジー制御タンパクRubicon発現上昇を介した肝細胞アポトーシスの亢進2014
- Author(s)
  田中　聡司、疋田　隼人、野崎　泰俊、甲斐　優吾、牧野　祐紀、中堀　輔、齋藤　義修、阪森　亮太郎、宮城　琢也、巽　智秀、竹原　徹郎
- Organizer
  第21回肝細胞研究会
- Place of Presentation
  東京
- Year and Date
  2014-06-27
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] Significance of Ras pathway and connective tissue growth factor in the development of hepatocellular carcinoma2014
- Author(s)
  Yuki Makino, Hayato Hikita, Tsukasa Kawaguchi, Takahiro Kodama, Minoru Shigekawa, Yugo Kai, Yasutoshi Nozaki, Tasuku Nakabori, Yoshinobu Saito, Satoshi Tanaka, Ryotaro Sakamori, Takuya Miyagi, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  Significance of Ras pathway and connective tissue growth factor in the development of hepatocellular carcinoma
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26670381
[Presentation] ASH病態形成におけるオートファジーとアポトーシスの意義2014
- Author(s)
  田中聡司　疋田隼人　竹原徹郎
- Organizer
  第18回日本肝臓学会大会（JDDW2014）
- Place of Presentation
  神戸
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-26253047
[Presentation] The crosstalk between apoptosis and autophagy in the pathogenesis of non-alcoholic fatty liver disease.2013
- Author(s)
  Satoshi Tanaka, Hayato Hikita, Tasuku Nakabori, Yoshinobu Saito, Satoshi Shimizu, Wei Li, Ryotaro Sakamori, Takuya Miyagi, Naoki Hiramatsu, Tomohide Tatsumi, Tetsuo Takehara.
- Organizer
  The 64th Annual Meeting of the American Association for the study of Liver Disease.
- Place of Presentation
  Washington　D.C., USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] NASH 肝障害・肝発癌の病態形成における, オートファジー抑制を介した持続的アポトーシスの寄与2013
- Author(s)
  田中聡司, 疋田隼人, 齋藤義修, 清水聡, 阪森亮太郎, 宮城琢也, 巽智秀, 竹原徹郎
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 肝細胞アポトーシスが発生する酸化ストレスの肝発癌に与える影響2013
- Author(s)
  疋田隼人, 巽智秀, 宮城琢也, 阪森亮太郎, 清水聡, 斉藤義修, 田中聡司, 竹原徹郎
- Organizer
  第49回肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] .Oxidative stress induced by continuous hepatocyte apoptosis drives liver carcinogenesis independently of regeneration and DNA methylation status.2013
- Author(s)
  Hayato Hikita, Tomohide Tatsumi, Yoshinobu Saito, Satoshi Tanaka, Satoshi Shimizu, Wei Li, Ryotaro Sakamori, Takuya Miyagi, Naoki Hiramatsu, Tetsuo Takehara.
- Organizer
  The 64th Annual Meeting of the American Association for the study of Liver Disease.
- Place of Presentation
  Washington　D.C., USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 慢性肝障害からの肝発癌におけるバイオマーカーの検討2013
- Author(s)
  疋田隼人, 巽智秀, 中堀輔, 斎藤義修, 田中聡司, 清水聡, 阪森亮太郎, 宮城拓也, 竹原徹郎
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 慢性肝障害からの肝発癌におけるバイオマーカーの検討2013
- Author(s)
  疋田隼人、巽智秀、中堀輔、斎藤義修、田中聡司、清水聡、阪森亮太郎、宮城拓也、竹原徹郎
- Organizer
  第１７回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] Oxidative stress induced by continuous hepatocyte apoptosis drives liver carcinogenesis independently of regeneration and DNA methylation status2013
- Author(s)
  Hayato Hikita, Tomohide Tatsumi, Yoshinobu Saito, Satoshi Tanaka, Satoshi Shimizu, Wei Li, Ryotaro Sakamori, Takuya Miyagi, Naoki Hiramatsu, Tetsuo Takehara
- Organizer
  The 64th Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Washington, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 肝細胞アポトーシスが発生する酸化ストレスの肝発癌に与える影響2013
- Author(s)
  疋田隼人、巽智秀、宮城琢也、阪森亮太郎、清水聡、斉藤義修、田中聡司、竹原徹郎
- Organizer
  第４９回肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 新しい培養技術による幹細胞を標的としたオーダーメード治療の可能性2013
- Author(s)
  林義人、近藤純平、竹原徹郎
- Organizer
  日本消化器病学会
- Place of Presentation
  鹿児島市
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-24390188
[Presentation] NASH肝障害・肝発癌の病態形成における、オートファジー抑制を介した持続的アポトーシスの寄与2013
- Author(s)
  田中聡司、疋田隼人、齋藤義修、清水聡、阪森亮太郎、宮城琢也、巽智秀、竹原徹郎.
- Organizer
  第１７回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] セルレイン急性膵炎において膵STAT3はPAP1の分泌を介して膵保護的に働く2013
- Author(s)
  重川稔、岩橋潔、池澤賢治、竹原徹郎
- Organizer
  第44回日本膵臓学会大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24659364
[Presentation] The crosstalk between apoptosis and autophagy in the pathogenesis of non-alcoholic fatty liver disease2013
- Author(s)
  Satoshi Tanaka, Hayato Hikita, Tasuku Nakabori, Yoshinobu Saito, Satoshi Shimizu, Wei Li, Ryotaro Sakamori, Takuya Miyagi, Naoki Hiramatsu, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 64th Annual Meeting of the American Association for the study of Liver Disease. The crosstalk between apoptosis and autophagy in the pathogenesis of non-alcoholic fatty liver disease
- Place of Presentation
  Washington, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] NAFLD/NASH 病態形成における, 飽和脂肪酸・不飽和脂肪酸によるオートファジーとアポトーシスの制御に関して2013
- Author(s)
  田中聡司, 疋田隼人, 齋藤義修, 清水聡, 阪森亮太郎, 宮城琢也, 巽智秀, 竹原徹郎
- Organizer
  第49回肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] NAFLD/NASH病態形成における、飽和脂肪酸・不飽和脂肪酸によるオートファジーとアポトーシスの制御に関して.2013
- Author(s)
  田中聡司、疋田隼人、齋藤義修、清水聡、阪森亮太郎、宮城琢也、巽智秀、竹原徹郎
- Organizer
  第４９回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] The BH3-only proteins, Bim and Bid, constitutively participate in the healthy Bcl-2 rheostat regulating hepatocyte life and death via the mitochondrial pathway of apoptosis.2012
- Author(s)
  Kodama T, Takehara T, et al.
- Organizer
  The American Association for the Study of Liver Diseases (AASLD), 63rd Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] Narrow band imaging with magnifying endoscopy for Peyer's patches in patients with inflammatory bowel disease2012
- Author(s)
  Hiyama S, Nishida T, Tsujii M, Takehara T.
- Organizer
  2012 Digestive Disease Week and the Annual Meeting of the American Society for Gastrointestinal Endoscopy
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Differential roles of palmitic acid and oleic acid in regulation of apoptosis and autophagy in non-alcoholic fatty liver disease2012
- Author(s)
  Satoshi Tanaka, Hayato Hikita1, Satoshi Aono, Tsukasa Kawaguchi, Kaori Mukai, Satoshi Shimizu, Takahiro Kodama, Wei Li, Takuya Miyagi, Tatsuya Kanto, Naoki Hiramatsu, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 63rd Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] Role of DNA methylation on epithelial mesenchymal transition (EMT)-like phenotype of colon cancer cells2012
- Author(s)
  Kondo J, Nishida T, Watabe K, Tsujii M, Takehara T.
- Organizer
  2012 Digestive Disease Week and the Annual Meeting of the American Society for Gastrointestinal Endoscopy
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Oxidative stresses play a major role in cancer development in apoptosis-prone liver.2012
- Author(s)
  Hikita H, Takehara T, et al.
- Organizer
  The American Association for the Study of Liver Diseases (AASLD), 63rd Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] Differential roles of palmitic acid and oleic acid in regulation of apoptosis and autophagy in non-alcoholic fatty liver disease.2012
- Author(s)
  Tanaka S, Takehara T, et al.
- Organizer
  The American Association for the Study of Liver Diseases (AASLD), 63rd Annual Meeting
- Place of Presentation
  Boston, MA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 胃癌発生と腸上皮化生H.pylori起因性胃発癌におけるCagAと腸上皮化生の役割2012
- Author(s)
  林　義人、辻井正彦、竹原徹郎
- Organizer
  日本消化器関連学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Bid and Bim are essential regulators involving the intrinsic pathway of apoptosis in hepatocytes in the absence of anti-apoptotic Bcl-2 family proteins2012
- Author(s)
  Takahiro Kodama, Hayato Hikita, Tsukasa Kawaguchi, Hinako Tsunematsu, Kumiko Nishio, Takatoshi Nawa, Minoru Shigekawa, Satoshi Shimizu, Wei Li, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Tetsuo Takehara
- Organizer
  The 63rd Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] Clinical features of late bleeding associated with heparin replacement after endoscopic resection for colorectal neoplasms2012
- Author(s)
  Inoue T, Iijima H, Tsujii M, Takehara T.
- Organizer
  2012 Digestive Disease Week and the Annual Meeting of the American Society for Gastrointestinal Endoscopy
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] ヘパリン置換療法下での大腸内視鏡的粘膜切除後出血の検討.シンポジウム;抗凝固薬・抗血小板薬服用患者の内視鏡診療を検証する2012
- Author(s)
  井上拓也,辻井正彦,竹原徹郎
- Organizer
  第83回日本消化器内視鏡学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Cyclooxygenase-2の癌幹細胞バイオロジー、DNA異常メチル化に及ぼす影響.ワークショップ;消化管がん分子病態診断学の進歩2012
- Author(s)
  辻井正彦,近藤純平,赤坂智史,林義人,金瑛,加藤元彦,山本俊祐,井上拓也,山田拓哉,西田勉,渡部健二,飯島英樹,竹原徹郎
- Organizer
  第8回日本消化管学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Long-term outcomes of ESD for patients with early gastric cancer and liver cirrhosis : a multicenter study by Osaka University ESD Study Group2012
- Author(s)
  Kato M, Tsujii M, Takehara T.
- Organizer
  2012 Digestive Disease Week and the Annual Meeting of the American Society for Gastrointestinal Endoscopy
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Oxidative stresses play a major role in cancer development in apoptosis-prone liver2012
- Author(s)
  Hayato Hikita, Takahiro Kodama, Satoshi Tanaka, Yoshinobu Saito, Satoshi Shimizu, Minoru Shigekawa, Wei Li, Takuya Miyagi, Tatsuya Kanto, Naoki Hiramatsu, Tomohide Tatsumi, Tetsuo Takehara
- Organizer
  The 63rd Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] ESD後の適切なフォローアップ方法～多発胃癌に対するサーベイランスの観点から～ESDフォーラム; Where is our destination?2012
- Author(s)
  加藤元彦,西田勉,山本克己,北村信次,由雄敏之,中村剛之,小森真人,河相直樹,西原彰浩,中西文彦,中原征則,荻山秀治,木下和郎,辻井正彦,竹原徹郎
- Organizer
  第8回日本消化管学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24659365
[Presentation] Pancreatic STAT3 protects caerulein-induced acute pancreatitis in mice via the PAP1 induction2012
- Author(s)
  Minoru Shigekawa, Hayato Hikita, Takahiro Kodama, Satoshi Shimizu, Takuya Miyagi, Atsushi Hosui, Tatsuya Kanto, Naoki Hiramatsu, Tomohide Tatsumi and Tetsuo Takehara.
- Organizer
  DDW2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659364
[Presentation] TIE2-expressing monocytes are feasible angiogenesis-related cellular diagnostics for hepatocellular carcinoma: Involvement of inflammatory cytokines in the generation2012
- Author(s)
  Matsubara T, Kanto T, Kuroda S, Yoshio S, Higashitani K, Miyazaki M, Hiramatsu N, Kasahara A, Takehara T
- Organizer
  The Liver Meeting AASLD 63rd Annual Meeting and Postgraduate Course
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-22590729
[Presentation] Pro-angiogenic receptor TIE2-expressing monocytes/TEM as novel diagnostic biomarker for hepatocellular carcinoma2012
- Author(s)
  Matsubara T, Kanto T, Kuroda S, Yoshio S, Higashitani K, Kakita N, Miyazaki M, Hiramatsu N, Kasahara A, Takehara T.
- Organizer
  The Liver Meeting AASLD 62nd Annual Meeting and Postgraduate Course
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-22590729
[Presentation] Delayed onset of caspase-dependent liver failure induced by Fas stimulation in Bak and Bax double knockout mice2011
- Author(s)
  Hayato Hikita, Takahiro Kodama, Satoshi Shimizu, Minoru Shigekawa, Atsushi Hosui, Takuya Miyagi, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Norio Hayashi, Tetsuo Takehara
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] 持続的な肝細胞アポトーシスは肝発癌を誘導する2011
- Author(s)
  疋田隼人、巽智秀、竹原徹郎
- Organizer
  JDDW2011(第19回日本消化器関連学会週間、第53回消化器病学会大会、第15回肝臓学会大会、第9回消化器外科学会大会、第82回消化器内視鏡学会総会)
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Multi-kinase inhibitor sorafenib induces autophagy which confers anti-cancer drug resistance to human hepatoma cells2011
- Author(s)
  Shimizu S, Tatsumi T, Takehara T(他9名)
- Organizer
  第62回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Interferon-αsuppresses hepatitis B virus enhancer II activity via PKC pathway2011
- Author(s)
  Nawa T, Tatsumi T, Takehara T(他9名)
- Organizer
  第62回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Multi-kinase inhibitor sorafenib induces autophagy which confers anti-cancer drug resistance to human hepatoma cells2011
- Author(s)
  Shimizu S, Takehara T, et al
- Organizer
  The American Association for the Study of Liver Diseases (AASLD), 62nd Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-23390197
[Presentation] 炎症性サイトカインInterleukin-1βは肝細胞癌の先天免疫回避に関与する2011
- Author(s)
  巽智秀、竹原徹郎(他1名)
- Organizer
  第47回肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] 肝細胞におけるp53の活性化は肝に線維化を誘導する2011
- Author(s)
  小玉尚宏、竹原徹郎、巽智秀(他10名)
- Organizer
  第47回肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] IFNαはB型肝炎ウイルスのエンハンサー2の転写活性を阻害する2011
- Author(s)
  名和誉敏、巽智秀、竹原徹郎(他4名)
- Organizer
  JDDW2011(第19回日本消化器関連学会週間、第15回肝臓学会大会)
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Requirement of BH3-only activator proteins Bid and Bim for apoptosis by genetic ablation of Bcl-xL is completely different between hepatocytes and platelets2011
- Author(s)
  Takahiro Kodama, Hayato Hikita, Tsukasa Kawaguchi, Minoru Shigekawa, Hinako Tsunematsu, Kumiko Nishio, Takatoshi Nawa, Satoshi Shimizu, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Hisashi Ishida, Tatsuya Kanto, Naoki Hiramatsu, Tetsuo Takehara
- Organizer
  The 62nd Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] Enhanced ability of IL28A and IL28B induction in plasmacytoid dendritic cells in chronic hepatitis C patients with major allele of IL28B single nucleotide polymorphism.2011
- Author(s)
  Kakita N, Kanto T, Miyazaki M, Yoshio S, Kuroda S, Matsubara T, Higashitani K, Sakakibara M, Hiramatsu N, Kasahara S, Takehara T, Hayashi N
- Organizer
  The Liver Meeting AASLD 62nd Annual Meeting and Postgraduate Course
- Place of Presentation
  San Francisco CA, USA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22590729
[Presentation] C型慢性肝炎のPEG-IFN/ RBV併用治療における治療効果とC型肝炎ウイルス特異的細胞傷害性T細胞(CTL)免疫反応の関連2011
- Author(s)
  巽智秀、竹原徹郎(他6名)
- Organizer
  第47回肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] A crucial role of hepatocyte p53 in liver fibrogenesis2011
- Author(s)
  Kodama T, Takehara T, Tatsumi T, (他10名)
- Organizer
  DDW2011/ AGA/ AASLD
- Place of Presentation
  米国シカゴ
- Year and Date
  2011-05-11
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Continuous hepatocyte apoptosis is sufficient for liver cancer development2011
- Author(s)
  Hayato Hikita, Takahiro Kodama, Satoshi Shimizu, Minoru Shigekawa, Wei Li, Satoshi Tanaka, Atsushi Hosui, Takuya Miyagi, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Norio Hayashi, Tetsuo Takehara
- Organizer
  The 62nd Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] Viral suppression at week 4 exceeds the IL28B SNP for predicting SVR in pegylated interferon plus ribavirin combination therapy of genotype 1 infected patients with chronic hepatitis.2011
- Author(s)
  Oze T, Hiramatsu N, Yakushijin T, Doi Y, Ogawa H, Hagiwara H, Mita E, Kaneko A, Katayama K, Hijioka T, Tamura S, Yoshihara H, Inoue A, Imai Y, Hayashi E, Hosui A, Miyagi T, Yoshida Y, Tatsumi T, Kiso S, Kanto T, Kasahara A, Hayashi N, Takehara T
- Organizer
  The Liver Meeting AASLD 62nd Annual Meeting and Postgraduate Course
- Place of Presentation
  San Francisco CA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22590729
[Presentation] Bak/ BaxダブルノックアウトマウスにおけるFasの活性化はカスパーゼ依存的な遅発性肝細胞死を誘導する2011
- Author(s)
  疋田隼人、巽智秀、竹原徹郎(他9名)
- Organizer
  第47回肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] 疎水化ポリγ-グルタミン酸ナノ粒子の癌抗原ペプチドワクチンにおけるアジュバントとしての有用性2011
- Author(s)
  明田寛史、巽智秀、竹原徹郎(他17名)
- Organizer
  JDDW2011(第19回日本消化器関連学会週間、第15回肝臓学会大会)
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] A crucial role of hepatocyte p53 in liver fibrogenesis2011
- Author(s)
  Takahiro Kodama, Tetsuo Takehara, Satoshi Shimizu, Hayato Hikita, Minoru Shigekawa, Hinako Tsunematsu, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Hisashi Ishida, Tatsuya Kanto, Naoki Hiramatsu, Norio Hayashi
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] Continuous hepatocyte apoptosis is sufficient for liver cancer development2011
- Author(s)
  Hikita H, Takehara T, et al
- Organizer
  The American Association for the Study of Liver Diseases (AASLD), 62nd Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] CD133陽性肝細胞癌はmetalloproteinaseを制御しその生存に有利な環境を作る2010
- Author(s)
  巽智秀、竹原徹郎(他7名)
- Organizer
  第69回癌学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] ABT-737, a bad minetic Bcl-xL inhitor enhances the anti-tumor effect of sorafenib against hepatocellular carcinoma.2010
- Author(s)
  Hikita H, Takehara T, Kanto T(11番目), 他
- Organizer
  第61回AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] ABT-737, a Bad mimetic Bcl-xL inhibitor. enhances the anti-tumor effect of sorafenib against hepatocellular carcinoma.2010
- Author(s)
  Hikita H, Takehara T, et al.
- Organizer
  The Liver Meeting 2010
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 肝細胞癌におけるADAMファミリーによる先天免疫応答制御機構の解析2010
- Author(s)
  甲賀啓介、巽智秀、竹原徹郎
- Organizer
  第52回日本消化器病学会大会
- Place of Presentation
  神奈川県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 「肝細胞癌にけるNK活性化レセプターNKG2Dリガンドの発現とADAMファミリーによるその制御」「NAFLD病態におけるinvariant NKT細胞が果たす役割」2010
- Author(s)
  甲賀啓介, 竹原徹郎, 他, 宮城琢也, 竹原徹郎, 他
- Organizer
  第96回日本消化器病学会総会(シンポジウム7 C型肝炎:ウイルス感染の分子免疫機構)(ワークショップ3 NASH/NAFLD発症のメカニズム)
- Place of Presentation
  )新潟県民会館、新潟市民芸術文化会館、新潟市音楽文化会館、朱鷺メッセ
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 分岐鎖アミノ酸のHCV増殖に与える影響2010
- Author(s)
  石田永、竹原徹郎、林紀夫
- Organizer
  第14回日本肝臓学会大会
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21590843
[Presentation] Distinctive roles of IL-10-producing type 1 regulatory T cells(TR1)in the pathogenesis of hepatitis C virus-infected hepatocellular carcinoma.2010
- Author(s)
  Kakita N, Kanto T, Takehara T (10番目), 他
- Organizer
  第61回AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] ABT-737, a Bad mimetic Bcl-xL inhibitor, enhances the anti-tumor effect of sorafenib against hepatocellular carcinoma2010
- Author(s)
  H. Hikita ; T. Takehara ; S. Shimizu ; T. Kodama ; W. Li ; M. Shigekawa ; A. Hosui ; T. Miyagi ; H. Ishida ; T. Tatsumi ; T. Kanto ; N. Hiramatsu ; N. Hayashi
- Organizer
  The 61st Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] 血小板による肝線維化抑制機構の解明2010
- Author(s)
  小玉尚宏、竹原徹郎、巽智秀(他8名)
- Organizer
  JDDW2010(第18回日本消化器関連学会週間、第52回消化器病学会大会)
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Sorafenibは肝細胞癌のADAM9は抑制することでMICAのsheddingを制御する2010
- Author(s)
  甲賀啓介、巽智秀、竹原徹郎(他6名)
- Organizer
  第69回癌学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Distinctive roles of IL-10-producing Type 1 regulatory T cells (Tr1) in the pathogenesis of hepatitis C virus-infected hepatocellular carcinoma2010
- Author(s)
  Kakita N, Kanto T, Matsubara T, Higashitani K, Miyazaki M, Sakakibara M, Hiramatsu N, Takehara T, Kasahara A, Hayashi N
- Organizer
  The Liver Meeting AASLD 61stAnnual Meeting and Postgraduate Course
- Place of Presentation
  Boston MA, USA
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22590729
[Presentation] 「C型肝炎からの肝発がん」「IFN-STAT1活性化が肝癌進展に及ぼす影響の検討」「Sorafenibは肝細胞癌のADAM9を抑制することでMICAのsheddingを制御する」「CD133陽性肝細胞癌はmetalloproteinaseを制御しその生存に有利な環境を作る」2010
- Author(s)
  竹原徹郎, 法水淳, 竹原徹郎, 他, 甲賀啓介, 竹原徹郎, 他, 巽智秀, 竹原徹郎, 他
- Organizer
  第69回日本癌学会学術総会(シンポジウム2ウイルス発がん)
- Place of Presentation
  大阪国際会議場リーガロイヤルホテル
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] α-fetoproteinによる先天免疫活性化抑制機構の解析2010
- Author(s)
  山本政司、巽智秀、竹原徹郎(他7名)
- Organizer
  第46回肝臓学会総会
- Place of Presentation
  山形県山形市
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] C型肝細胞癌における制御性T細胞の誘導機序解明2010
- Author(s)
  垣田成庸、考藤達哉、竹原徹郎 (11番目), 他
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Perturbation of HCV replication by microRNAs which are regulated by HCV infection2010
- Author(s)
  石田永、竹原徹郎、林紀夫
- Organizer
  17^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21590843
[Presentation] The role of IFN-STAT1 signal transduction on inhibition of HCC development2010
- Author(s)
  法水淳, 竹原徹郎, et al.
- Organizer
  The Liver Meeting 2010
- Place of Presentation
  Boston Hynes Convention Center
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] CD133陽性肝癌細胞のmetalloproteinaseによる制御2010
- Author(s)
  巽智秀、竹原徹郎(他1名)
- Organizer
  JDDW2010(第18回日本消化器関連学会週間、第52回消化器病学会大会)
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] 「IFN-STAT1活性化が肝癌進展に及ぼす影響の検討」「a-fetoproteinによる先天免疫活性化抑制機構の解析」2010
- Author(s)
  法水淳, 竹原徹郎, 他, 山本政司, 竹原徹郎, 他
- Organizer
  第46回日本肝臓学会総会(シンポジウム2肝細胞癌の分子標的探索と臨床応用)
- Place of Presentation
  ホテルメトロポリタン山形、山形テルサ、山形国際ホテル
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] ABT-737, a Bad mimetic Bcl-xL inhibitor, enhances the anti-tumor effect of sorafenib against hepatocellular carcinoma.2010
- Author(s)
  Hikita H, Takehara T, et al.
- Organizer
  The Liver Meeting 2010
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] The role of IFN-STAT1 signal transduction on inhibition of HCC development2010
- Author(s)
  Hosui A, Takehara T, Tatsumi T(他9名)
- Organizer
  第61回米国肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] C型慢性肝疾患患者におけるミエロイド樹状細胞のI型、III型IFN産生能の低下-IL-29とIL-28Aの検討2010
- Author(s)
  宮崎昌典、考藤達哉、竹原徹郎 (9番目), 他
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Pro-angiogenic receptor TIE2-expressing monocytes/ TEMs as novel diagnostic biomarker for hepatocellular carcinoma.2010
- Author(s)
  Matsubara T, Kanto T, Higashitani K, Kakita N, Miyazaki M, Inoue M, Sakakibara M, Hiramatsu N, Takehara T, Kasahara A, Hayashi N.
- Organizer
  The Liver Meeting AASLD 61stAnnual Meeting and Postgraduate Course
- Place of Presentation
  Boston MA, USA
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22590729
[Presentation] 「α-fetoprotein impairs NK activity by inhibiting dendritic cell function 」「Anti-cancer chemotherapy enhances NK sensitivity by inhibiting MICA ectodomain shedding in human hepatocellular carcinoma」2009
- Author(s)
  Yamamoto M, Takehara T, et al., Kohga K, Takehara T, et al.
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Feasibility of IL-10 producing regulato y type 1 cells for the monitoring of viable hepatocellular carcinoma through local ablation therapy.2009
- Author(s)
  Kakita N, Kanto T, Takehara T (12 番目), 他
- Organizer
  第60回AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 非アルコール性脂肪性肝炎病態進展におけるInvariant NKT細胞の役割2009
- Author(s)
  宮城琢也, 竹原徹郎, 他
- Organizer
  JDDW 2009(パネルディスカッション11自然免疫と消化器疾患)
- Place of Presentation
  国立京都国際会館、グランドプリンスホテル京都
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] α-fetoprotein impairs NK activity by inhibiting dendritic cell function2009
- Author(s)
  Yamamoto M, Tatsumi T, Takehara T(他4名)
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Anti-cancer chemotherapy enhances NK sensitivity by inhibiting MICA ectodomain shedding in human hepatocellular carcinoma2009
- Author(s)
  Kohga K, Tatsumi T, Takehara T(他4名)
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Interferon-α-signaling in natural killer cells is impaired in chronic hepatitis C virus infection2009
- Author(s)
  Miyagi T, Takehara T, Tatsumi T, (他4名)
- Organizer
  第60回米国肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2009-11-02
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] 「非アルコール性脂肪性肝炎病態形成におけるNKT細胞の関与」「肝細胞癌におけるNK活性化レセプターリガンドMICA分泌(shedding)の分子機構」「α-PGAナノ粒子を用いた癌免疫療法の基礎的検討」「肝細胞特異的STAT5欠損マウスにおける肝線維化・発がんの分子機構」2009
- Author(s)
  宮城琢也, 竹原徹郎, 他, 甲賀啓介, 竹原徹郎, 他, 山口真二郎, 竹原徹郎, 他, 法水淳, 竹原徹郎, 他
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸ポートピアホテル、神戸国際展示場
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 肝細胞癌におけるNK活性化レセプターリガンドMICA分泌(shedding)の分子機構2009
- Author(s)
  甲賀啓介、竹原徹郎, 他
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 血小板減少は胆汁鬱滞性肝障害における肝繊維化を増悪させる2009
- Author(s)
  小玉尚宏、竹原徹郎、巽智秀(他10名)
- Organizer
  第45回肝臓学会総会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] 肝細胞癌におけるNK活性化レセプターリガンドMICA分泌(sheddong)の分子機構2009
- Author(s)
  甲賀啓介、竹原徹郎, 他13名
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  兵庫県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Perturbation of HCV replication by microRNAs which are regulated by HCV infection2009
- Author(s)
  石田永、竹原徹郎、林紀夫
- Organizer
  The Liver Meeting 2009-AASLD's 60th Annual Meeting
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21590843
[Presentation] Perturbation of HCV replication by microRNAs which are regulated by HCV infection2009
- Author(s)
  石田永, 竹原徹郎, 林紀夫
- Organizer
  The Liver Meeting 2009-AASLD's 60th Annual Meeting
- Place of Presentation
  John B. Hynes Convention Center (Boston, USA)
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21590843
[Presentation] Interferon-α-signaling in natural killer cells is impaired in chronic hepatitis C virus infection.2009
- Author(s)
  宮城琢也, 竹原徹郎, 他5名
- Organizer
  第60回AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 肝細胞癌におけるNK活性化レセプターリガンドMICA分泌(shedding)の分子機構2009
- Author(s)
  甲賀啓介、竹原徹郎、巽智秀(他12名)
- Organizer
  第45回肝臓学会総会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590841
[Presentation] Dynamics of plasmacytoid dendritic cells as a predictor of relapse regardless of virological response in pegylated interferon-α and ribavirin therapy in chronic hepatitis C patients.2009
- Author(s)
  Kanto T, Takehara T (13番目),他
- Organizer
  第60回AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] α-galactosylceramideによる肝樹状細胞の活性化機構の解析2009
- Author(s)
  笹川哲, 竹原徹郎, 他
- Organizer
  第23回肝類洞壁細胞研究会学術集会
- Place of Presentation
  ホテル京阪ユニバーサルタワー(大阪)
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] α-fetoproteinによる免疫抑制-NK細胞による細胞障害活性について2009
- Author(s)
  山本政司, 竹原徹郎, 他
- Organizer
  第45回日本肝癌研究会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 「C型肝炎に対するIFN治療における免疫エフェクター細胞内シグナル伝達解析」「肝発癌過程におけるSTAT5の役割」2009
- Author(s)
  宮城琢也, 竹原徹郎, 他, 法水淳, 竹原徹郎, 他
- Organizer
  第95回日本消化器病学会総会(パネルディスカッション6 C型肝炎治療の最前線)(ワークショップ4肝細胞癌の予防)
- Place of Presentation
  北海道厚生年金会館、ロイトン札幌、京王プラザホテル札幌
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Thrombocytopenia deteriorates cholestasis-induced liver fibrosis in mice2009
- Author(s)
  Kodama T, Takehara T, Hikita H, Shimizu S, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Tadokoro S, Ido A, Tsubouchi H, Hayashi N
- Organizer
  The 60th Annual Meeting of the American Association for the study of Liver Disease
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] C型肝細胞癌の治療・再発過程における制御性T細胞サブセットの意義2009
- Author(s)
  垣田成庸、考藤達哉、竹原徹郎 (11番目), 他
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  兵庫県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Myeloid dendritic cells as a theraputic target for immune restoration by HCV NS3 protease inhibitor in chronic hepatitis C patients.2009
- Author(s)
  Miyazaki M, Kanto T, Takehara T (10番目), 他
- Organizer
  第60回AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Thrombocytopenia deteriorates cholestasis-induced liver fibrosis in mice2009
- Author(s)
  Kodama T, Takehara T, et al.
- Organizer
  The American Association for the Study of Liver Diseases, 60^<th> Annual Meeting AASLD
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Bcl-xL and Mcl-1 cooperate to maintain integrity of hepatocytes2009
- Author(s)
  Hikita H, Takehara T, et al.
- Organizer
  The American Association for the Study of Liver Diseases, 60^<th> Annual Meeting AASLD
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-21659188
[Presentation] 「Interferon-α-signaling in natural killer cells is impaired in chronic hepatitis C virus infection」「Lack of invariant natural killer T cells elicits liver inflammation and predisposes to liver fibrosis in mice fed with high-fat diet」2009
- Author(s)
  Miyagi T, Takehara T, et al., Nishio K, Takehara T, et al.
- Organizer
  The Liver Meeting 2009
- Place of Presentation
  Boston HYNES CONVENTION CENTER
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] HCVプロテアーゼ阻害剤によるミエロイド樹状細胞の機能回復効果2009
- Author(s)
  宮崎昌典、考藤達哉、竹原徹郎 (9番目), 他
- Organizer
  第13回日本肝臓学会大会
- Place of Presentation
  京都府
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] BH3-only protein Bid isrequired for hepatocyte apoptosiscaused by Bcl-xL deficiency2008
- Author(s)
  Hikita H, Takehara T, Tatsumi T, (他10名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] SN38は肝癌細胞のNK細胞感受性を増強させる2008
- Author(s)
  甲賀啓介, 竹原徹郎, 他
- Organizer
  第44回日本肝癌研究会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Expression of NKG2D activatingreceptor on natural killer cells inchronic hepatitis C.2008
- Author(s)
  Shimizu S, Takehara T, Tatsumi T, (他14名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Natural regulatory T cells as biomarker for the assessment of hepatocellular caricinoma in local ablation therapy.2008
- Author(s)
  Kakita N, Kanto T, Takehara T (10番目), 他
- Organizer
  第59回AASLD
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] C型肝炎における持続感染・発がんと自然免疫病態2008
- Author(s)
  竹原徹郎
- Organizer
  第12回九州肝不全研究会
- Place of Presentation
  ソラリア西鉄ホテル(博多)(教育講演)
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 高齢者C型肝炎に対するPeg-IFN/Ribavirin併用療法2008
- Author(s)
  平松直樹、竹原徹郎、林紀夫
- Organizer
  第94回日本消化器病学会
- Place of Presentation
  福岡県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] SN38 は肝癌細胞の可溶性NK 活性リガンドの分泌を抑制しNK 細胞感受性を増強させる2008
- Author(s)
  甲賀啓介、竹原徹郎、巽智秀、(他11名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Efficacy of theimmunotherapy with γ-polyglutamicacid nanoparticles in mouse livertumor2008
- Author(s)
  Yamaguchi S, Tatsumi T, Takehara T, ( 他14名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Extended treatment withpeginterferon alfa-2b and ribavirincombination therapy can suppress therelapse rate after treatment ofchronic hepatitis C genotype 1patients with late viral response2008
- Author(s)
  Oze T, Tatsumi T, Takehara T, (他28名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] C型慢性肝炎におけるIL-7の意義-樹状細胞を介したTh2反応誘導効果2008
- Author(s)
  宮竹秀、考藤達哉、竹原徹郎 (9番目), 他
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] Supportive activity of PreCoreand PreS2 viral genomic changesagainst replication ofLamivudine-resistant hepatitis Bvirus2008
- Author(s)
  Ohkawa K, Takehara T, Tatsumi T, (他9名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] 難治性C 型肝炎に対するPeg-IFN/Ribavirin 併用療法でのEVR 例における薬剤adherence の影響-多施設(OLF)共同研究-2008
- Author(s)
  小瀬嗣子、竹原徹郎、巽智秀、(他18名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] C型肝炎に対するインターフェロン治療における免疫細胞内シグナル伝達解析による治療効果予測の可能性2008
- Author(s)
  宮城琢也、竹原徹郎、林紀夫
- Organizer
  第12回日本肝臓学会大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] IL-12遺伝子による肝臓NK細胞の活性化および転移性肝腫瘍の治療効果にはリンパ球からのIFNу産生が重要である2008
- Author(s)
  植村彰夫、竹原徹郎、考藤達哉 (12番目), 他
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] C型肝炎・肝がんの自然免疫病態2008
- Author(s)
  竹原徹郎
- Organizer
  肝疾患と代謝
- Place of Presentation
  帝国ホテル大阪(特別講演)
- Year and Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Regulation of NKG2D immunoreceptor by soluble form of MHC class I-related chain A in hepatocellular carcinoma2008
- Author(s)
  竹原徹郎
- Organizer
  13^<th> US-Japan GI & Liver Meeting in 21st Century
- Place of Presentation
  Sheraton Miyako Hotel Tokyo
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 「EFFICACY OF THE IMMUNOTHERAPY WITH POLYγ-GLUTAMIC ACID NANOPARTICLES IN MOUSE LIVER TUMOR」「EXPRESSION OF NKG2D ACTIVATING RECEPTOR ON NATURAL KILLER CELLS IN CHRONIC HEPATITIS C」「ACTIVATED LIVER DENDRITIC CELLS ARE MORE IMMUNOGENIC THAN SPLEEN DENDRITIC CELLS AFTER α-GALCER TREATMENT」「SN38 INHIBITS SHEDDING OF MHC CLASS1-RELATED CHAIN A, A LIGAND OF NKG2D IMMUNORECEPTOR IN HUMAN HEPATOCELLULAR CARCINOMA CELLS」2008
- Author(s)
  Yamaguchi S, Takehara T, et al., Shimizu S, Takehara T, et al., Sasakawa A, Takehara T, et al., Kohga K, Takehara T, et al.
- Organizer
  The Liver Meeting 2008
- Place of Presentation
  San Francisco, Moscone West Convention Center
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Activated liver dendritic cells are more immunogenic than spleen dendritic cells after α-galcer treatment.2008
- Author(s)
  Sasakawa A, Takehara T (3番目), 他
- Organizer
  第59回AASLD
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 難治性C 型肝炎に対するPeg-IFN/Ribavirin 長期投与の有用性について-多施設(OLF)共同研究-2008
- Author(s)
  小瀬嗣子、竹原徹郎、巽智秀、(他17名)
- Organizer
  第12回肝臓学会大会
- Place of Presentation
  東京都港区
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] C型肝炎に対するインターフェロン治療における免疫細胞内シグナル伝達解析による治療効果予測の可能性2008
- Author(s)
  宮城琢也, 竹原徹郎, 他
- Organizer
  JDDW 2008
- Place of Presentation
  グランドプリンスホテル新高輪、国際館パミール、グランドプリンスホテル高輪(シンポジウム14 C型肝炎の近未来治療)
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] BcL-xL は生体内肝細胞におけるBid の恒常的活性化によるアポトーシスを抑制する2008
- Author(s)
  疋田隼人、竹原徹郎、巽智秀、(他13名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] 肝先天免疫活性化による肝樹状細胞活性化機構の解析2008
- Author(s)
  笹川哲、竹原徹郎(3番目)、考藤達哉(13番目)、他11名
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] ウイルス感染モデルを用いたインターフェロンの免疫細胞内におけるシグナル伝達機構の制御メカニズムに関する基礎的検討2008
- Author(s)
  宮城琢也、竹原徹郎、巽智秀、(他2名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] C型肝炎の病態と自然免疫2008
- Author(s)
  竹原徹郎
- Organizer
  第45回日本消化器免疫学会総会
- Place of Presentation
  メルパルク京都(イブニングセミナー)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 「SN38は肝癌細胞の可溶型NK活性リガンドの分泌を抑制しNK細胞感受性を増強させる」「IL-12遺伝子による肝臓NK細胞の活性化および転移性肝腫瘍の治療効果にはリンパ球からのIFN・の産生が重要である」「皮下腫瘍担癌マウスにおける肝樹状細胞上CD1d分子発現低下による肝先天免疫の抑制」「肝先天免疫活性化による肝樹状細胞活性化機構の解析」「ウイルス感染モデルを用いたインターフェロンの免疫細胞内におけるシグナル伝達機構の制御メカニズムに関する基礎的検討」2008
- Author(s)
  甲賀啓介, 竹原徹郎, 他, 植村彰夫, 竹原徹郎, 他, 巽智秀, 竹原徹郎, 他, 笹川哲, 竹原徹郎, 他, 宮城琢也, 竹原徹郎, 他
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛県県民文化会館、愛媛看護研修センター(松山)(ワークショップ3肝の発癌と進展における分子代謝学的研究)
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] NK細胞による肝癌認識機構の分子機序の解析と新規治療法の探索2008
- Author(s)
  竹原徹郎、甲賀啓介、林紀夫
- Organizer
  第94回日本消化器病学会
- Place of Presentation
  福岡県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] C型肝細胞癌患者における制御性T細胞の意義2008
- Author(s)
  垣田成庸、考藤達哉、竹原徹郎 (9番目)、他
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 「NK cell expression of NKG2D is impaired in patients with chronic hepatitis C」「Immunotherapy with gamma poly-glutamic acid nanoparticles in mouse liver tumor」2008
- Author(s)
  Shimizu S, Yamaguchi S, Takehara T, et al.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] 難治性C型肝炎に対するPeg-IFN/Ribavirin長期投与の有用性について-他施設(OLF)共同研究-2008
- Author(s)
  小瀬嗣子、竹原徹郎(3番目)、他18名
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 肝先天免疫活性化による肝樹状細胞活性化機構の解析2008
- Author(s)
  笹川哲、巽智秀、竹原徹郎、(他11名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Critical role of IFNγ producedfrom NK cells in IL-12-mediated NKcell activation and anti-tumor effectin the liver2008
- Author(s)
  Uemura A, Takehara T, Tatsumi T, (他14名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] ラミブジン耐性B 型肝炎ウイルス成立機転に対するprecore ならびにpreS2 変異の補助的役割2008
- Author(s)
  大川和良、竹原徹郎、巽智秀、(他12名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Dynamic changes of regulatory T cell subsets in patients with chronic HCV infection in relation to the degree of liver inflammation.2008
- Author(s)
  Itose I, Kanto T, Takehara T (10番目), 他
- Organizer
  第59回AASLD
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] HCV陽性PNALT患者における制御性T細胞サブセットの意義2008
- Author(s)
  糸瀬一陽、考藤達哉、竹原徹郎 (9番目)、他
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] 皮下腫瘍担癌マウスにおける肝樹状細胞上CD1d 分子発現低下による肝先天免疫の抑制2008
- Author(s)
  巽智秀、竹原徹郎、(他13名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Ribavirin dose reduction raisesrelapse rate dose-dependently ingenotype 1 patients with chronichepatitis C responding to pegylatedinterferon alfa-2b plus ribavirin2008
- Author(s)
  Oze T, Tatsumi T, Takehara T, (他26名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Activated liver dendritic cellsare more immunogenic than spleendendritic cells after α-GalCertreatment2008
- Author(s)
  Sasakawa A, Tatsumi T, Takehara T, (他11名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] 皮下腫瘍担癌マウスにおける肝樹状細胞上CDld分子発現低下による肝先天免疫の抑制2008
- Author(s)
  巽智秀、竹原徹郎、考藤達哉 (14番目)(他12名)
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-20249043
[Presentation] SN38 inhibits the shedding ofMHC class1-related chain A, a ligandof NKG2D immunoreceptor in humanhepatocellular carcinoma cells2008
- Author(s)
  Kohga K, Takehara T, Tatsumi T, (他14名)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] SN38 INHIBITS SHEDDING OF MHC CLASS1-RELATED CHAIN A, A LIGANDOF NKG2D IMMUNORECEPTOR IN HUMAN HEPATOCELLULAR CARCINOMA CELLS.2008
- Author(s)
  Kohga K, Takehara T, etal.
- Organizer
  The American Association for the study of Liver Diseases, 59th Annual Meeting AASLD
- Place of Presentation
  San Francisco (DSA)
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] IL-12 遺伝子による肝臓NK 細胞の活性化および転移性肝腫瘍治療効果にはリンパ球からのIFN-γ産生が重要である2008
- Author(s)
  植村彰夫、竹原徹郎、巽智秀、(他11名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] NK細胞による肝癌認識機構の分子機序の解析と新規治療法の探索2008
- Author(s)
  竹原徹郎
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡国際会議場、福岡サンパレス、マリンメッセ福岡(シンポジウム9ウイルス肝炎・肝癌に対する生体防御)
- Data Source
  KAKENHI-PROJECT-20390208
[Presentation] Peg-IFN/Ribavirin 併用療法における高感度HCV-RNA 測定法(TaqMan 法)の有用性について2008
- Author(s)
  小瀬嗣子、竹原徹郎、巽智秀、(他12名)
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Dendritic cell-based vaccines suppress liver tumor viaactivation of innate and acquired immunity2007
- Author(s)
  阪森亮太郎、巽智秀、竹原徹郎、( 他8名)
- Organizer
  第66回癌学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] 樹状細胞投与による肝先天免疫の活性化と予防的肝癌免疫治療の検討2007
- Author(s)
  山口真二郎、巽智秀、竹原徹郎、(他9名)
- Organizer
  第93回消化器病学会総会
- Place of Presentation
  青森県青森市
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] IFN γ is critically required for IL12-mediated NK cell activation and anti-tumor effect in the liver2007
- Author(s)
  Uemura A, Takehara T, Tatsumi T, ( 他10名)
- Organizer
  第58回米国肝臓学会
- Place of Presentation
  米国ボストン
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] 肝腫瘍に対する新規癌抗原EphA2 を用いたDC ワクチン療法の基礎的検討2007
- Author(s)
  山口真二郎、巽智秀、竹原徹郎、(他8名)
- Organizer
  第43回肝臓学会総会
- Place of Presentation
  東京都港区
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Administration of α-galactosylceramide induces liver acquired immunity after liver tumor rejection2007
- Author(s)
  巽智秀、竹原徹郎、(他8名)
- Organizer
  第66回癌学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Hepatic STAT3 attenuates systemic inflammatory response and lethality in septic mice.2007
- Author(s)
  Sakamori R, Takehara T, Tatsumi T, (他7名)
- Organizer
  第58回米国肝臓学会
- Place of Presentation
  米国ボストン
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Regulation of the NKG2D immunoreceptor by soluble MICA during transcatheter arterial embolization for hepatocellular carcinoma2007
- Author(s)
  Kohga, K., Takehara, T., Hikita, H., Sasakawa, A., Uemura, A., Sakamori, R., Yamaguchi, S., Tatsumi, T., Ohkawa, K., Kanto, T., Hiramatsu, N., Katayama, K., Kato, M., Hayashi, N
- Organizer
  The American Association for the Study of Liver Diseases The 58th Annual Meeting AASLD
- Place of Presentation
  Hynes Convention Center, Boston, MA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Presentation] 肝臓におけるSTAT3 の活性化は敗血症時のTNF-αの産生を抑制し生存率を向上させる2007
- Author(s)
  阪森亮太郎、竹原徹郎、巽智秀、(他6名)
- Organizer
  第43回肝臓学会総会
- Place of Presentation
  東京都港区
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Activation of liver dendritic cells by administration of α-galactosylceramide.2007
- Author(s)
  笹川哲、巽智秀、竹原徹郎、(他5名)
- Organizer
  第66回癌学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Regulation of the NKG2D immunoreceptor by soluble MICA during tran scatheter arterial embolization for hepatocellular, carcinoma.2007
- Author(s)
  Kohga K, Takehara T, et. al.
- Organizer
  58th Annual Meeting, The American Association for the Study of Liver Diseases
- Place of Presentation
  Boston (USA)
- Data Source
  KAKENHI-PROJECT-18390216
[Presentation] Dynamic regulation of the NKG2D immunoreceptor expression by soluble MICA during TAE for hepatocellular carcinoma2007
- Author(s)
  甲賀啓介、竹原徹郎、巽智秀、 (他7名)
- Organizer
  第66回癌学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Regulation of the NKG2D immunoreceptor by soluble MICA during transcatheter arterial embolization for hepatocellular carcinoma.2007
- Author(s)
  Kohga K, Takehara T, et. al.
- Organizer
  58th Annual Meeting, The American Association for the Study of Liver Diseases
- Place of Presentation
  Boston(USA)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390216
[Presentation] Regulation of the NKG2D immunoreceptor by soluble MICA during transcatheter arterial embolizationfor hepatocellular carcinoma.2007
- Author(s)
  Kohga K, Takehara T, Tatsumi T, (他11名)
- Organizer
  第58回米国肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Soluble forms of human NKG2D ligands MICA/B increase in sera of patients with liver cirrhosis and HCC2007
- Author(s)
  疋田隼人、竹原徹郎、巽智秀、 (他7名)
- Organizer
  第66回癌学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Hepatic STAT3 attenuates systemic inflammatory response and lethality in septic mice2007
- Author(s)
  Sakamori R, Takehara T, et. al.
- Organizer
  58th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston(USA)
- Data Source
  KAKENHI-PROJECT-19659182
[Presentation] B型急性肝炎と劇症肝炎におけるB型肝炎ウイルスDNA全塩基配列の比較2007
- Author(s)
  金田愛衣美、竹原徹郎、大川和良, ら
- Organizer
  第93回日本消化器病学会総会
- Place of Presentation
  青森
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-18599003
[Presentation] Impact of reducing peginterferon alfa-2b and ribavirin on early viral response in genotype 1 infected patients with chronichepatitis C2007
- Author(s)
  Oze T, Takehara T, Tatsumi T, (他22名)
- Organizer
  第58回米国肝臓学会
- Place of Presentation
  米国ボストン
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] α-galactosylceramide による肝樹状細胞活性化機構の解析2007
- Author(s)
  笹川哲、竹原徹郎、巽智秀、(他9名)
- Organizer
  第43回肝臓学会総会
- Place of Presentation
  東京都港区
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] NKT細胞活性化を介した肝癌特異的獲得免疫の誘導2007
- Author(s)
  巽智秀、竹原徹郎、(他11名)
- Organizer
  第43回肝臓学会総会
- Place of Presentation
  東京都港区
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2 derived peptide-pulsed dendritie cell vaccines2007
- Author(s)
  山口真二郎、巽智秀、竹原徹郎、(他8名)
- Organizer
  第66回癌学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590766
[Presentation] H. pylori除菌後の胃発癌リスクに関する検討
- Author(s)
  林　義人、辻井正彦、竹原徹郎
- Organizer
  IDDW
- Place of Presentation
  神戸
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24390188
[Presentation] Vitamin K-deficiency deteriorates murine dextran sodium salt-induced colitis.
- Author(s)
  Iijima H, Shiraishi E, Shinzaki S, Inoue T, Hiyama S, Kawai S, Araki M, Nakajima S, Hayashi Y, Nishida T, Tsujii M, Takehara T.
- Organizer
  The 2nd Annual Meeting of Asian Organization for Crohn’s & Colitis
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-06-19 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-24390188
[Presentation] H. pylori CagAの胃発癌機構における役割
- Author(s)
  林　義人、辻井正彦、竹原徹郎
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23 – 2014-04-25
- Data Source
  KAKENHI-PROJECT-24390188
[Presentation] p53欠損大腸癌の癌微小環境に対する役割
- Author(s)
  林　義人、辻井正彦、竹原徹郎
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23 – 2014-04-25
- Data Source
  KAKENHI-PROJECT-24390188

1. TATSUMI Tomohide (20397699)

# of Collaborated Projects: 16 results

# of Collaborated Products: 194 results
2. HIRAMATSU Naoki (30362700)

# of Collaborated Projects: 8 results

# of Collaborated Products: 35 results
3. HIKITA Hayato (20623044)

# of Collaborated Projects: 7 results

# of Collaborated Products: 82 results
4. KANTO Tatsuya (80372613)

# of Collaborated Projects: 6 results

# of Collaborated Products: 62 results
5. OHKAWA Kazuyoshi (80432540)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
6. HAYASHI Norio (00144478)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
7. TSUJII Masahiko (40303937)

# of Collaborated Projects: 3 results

# of Collaborated Products: 64 results
8. HAYASHI Yoshito (80647123)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
9. IIJIMA Hideki (90444520)

# of Collaborated Projects: 3 results

# of Collaborated Products: 48 results
10. 小玉尚宏 (10623275)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
11. MOCHIZUKI Kiyoshi (50467578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. ISHIDA Hisashi (00506230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
13. NISHIDA Tsutomu (20467575)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
14. SHIGEKAWA Minoru (00625436)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
15. 近藤純平 (80624593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
16. TANAKA Satoshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
17. MIYAGI Takuya (80532986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. HOSUI Atsushi (10536882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. Makino Yuki (60771334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
20. 渡部健二 (50379244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. 阪森亮太郎 (10644685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
22. IKEZAWA Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. SAKANE Sadatsugu

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
24. TOYAMA Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. IWAHASHI Kiyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. SUEYOSHI Hironari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 中西文彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. FUJITA Naonobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. SATOH Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 仲哲治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 新崎信一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
32. 三善英知

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Takehara Tetsuo 竹原 徹郎

TAKEHARA Tetsuo 竹原 徹郎

Research Projects

Research Products

Co-Researchers

Mechanisms of cancer cell clonal expansion via phenotypic and spatial diversity in the cancer microenvironment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of hepatic progenitor cell-derived carcinogenic mechanism via p53 activation in hepatocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of pancreatic cancer metastasis using single cell analysis technology and innovative mouse modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell-to-cell communication and pathogenesis triggered by hepatocyte cell death in the liverPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

障害ミトコンドリアからのダイイングコード漏出による脂肪性肝疾患の進展機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝細胞と脂肪細胞におけるRubiconを介した脂肪代謝の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment for acute pancreatitis by regulating autophagy which modulates zymogen granules and inflammasomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The impact of hepatocyte apoptosis and autophagy in the process of livercarcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Significance of connective tissue growth factor (CTGF) and tumor-stroma interaction in Kras-driven hepatocarcinogenesis and HCC progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of acinar cell injury in acute pancreatitisPrincipal Investigator

Takehara Tetsuo 竹原徹郎

TAKEHARA Tetsuo 竹原徹郎