Yoda Akinori 依田成玄

… Alternative Names

YODA AKINORI 依田成玄

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Researcher Number	70335454
Other IDs
External Links
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 京都大学, 医学研究科, 特定准教授 2009: 神戸大学, 大学院・医学研究科, 助教 2008: 神戸大, 医学(系)研究科(研究院), 助教 2007 – 2008: Kobe University, 大学院・医学系研究科, 助教 2005 – 2006: 神戸大学, 大学院医学系研究科, 助手 2001 – 2004: 神戸大学, 大学院・医学系研究科, 助手
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 48040:Medical biochemistry-related / Basic Section 52010:General internal medicine-related / Biological Sciences Except Principal Investigator Biological Sciences / Broad Section I / General medical chemistry
Keywords	Principal Investigator マウスモデル / 白血病 / 急性骨髄性白血病 / 急性巨核球性白血病 / 急性赤白血病 / 分子標的薬 / PDX / GNB2 / 治療抵抗性 / スプライシング因子 … More / がん免疫 / スプライシング / AML / 悪性腫瘍 / チェックポイント機構 / Wip1ホスファターゼ / Chk2キナーゼ / DNA損傷応答 … More Except Principal Investigator シグナル伝達 / がん抑制遺伝子産物 / がん遺伝子産物 / DNA損傷 / 悪性リンパ腫 / Wip1ホスファターゼ / Chk2キナーゼ / DNA損傷応答 / Wnt5a / Wip1 ホスファターゼ / Chk2 キナーゼ / 細胞周期 / Chk1キナーゼ / 腫瘍学 / クローン進化 / オルガノイド / 単一細胞シーケンス / 全ゲノムシーケンス / 腫瘍生物学 / ゲノム生物学 / JNK / フィラミンA / Srcファミリーチロシンキナーゼ / MMP13 / 浸潤突起 / 細胞骨格再編成 / Ror2受容体チロシンキナーゼ / 細胞骨格 / 細胞極性 / 細胞移動 / Ror2受容体キナーゼ / 悪性腫瘍 / WIP1ホスファターゼ / ATMキナーゼ / がんの分子標的治療 / 核内シングル伝達 / チェックポイントキナーゼ / チェツクポイント機構 / リン酸化・脱リン酸化 / チェックポイント機構 / がん原遺伝子産物 / 癌の浸潤 / 14-3-3 / 癌化 / がんの浸潤 / Ror2シグナル / がん化 / 細胞周期チェックポイント / ヒストン脱アセチル化 / DNAメチル化 / Wip1 / Chk2 / 蛋白質ホスファターゼ / セリン・スレオニンキナーゼ / 癌抑制遺伝子産物 / HIF1 / c-Myc / H-Ras / リンパ球 Less

PDX models of rare hematopoietic malignancies for novel cancer therapiesPrincipal Investigator
- Principal Investigator
  
  依田成玄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kyoto University
Cancer immunotherapy targeting neo-self antigens in splicing factor mutated cellsPrincipal Investigator
- Principal Investigator
  
  依田成玄
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
comprehensive studies on the molecular basis of early development and clonal evolution in cancer using advanced genomics.
- Principal Investigator
  
  Ogawa Seishi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kyoto University
Development of diagnosis and treatment of novel drug targets using refractory leukemia modelsPrincipal Investigator
- Principal Investigator
  
  Yoda Akinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kyoto University
がん遺伝子産物Wip1ホスファターゼによるDNA損傷応答制御Principal Investigator
- Principal Investigator
  
  依田成玄
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Analysis of regulatory mechanisms for cell migration and cell polarity by Wnt5a and Ror2 receptor tyrosine kinase
- Principal Investigator
  
  MINAMI Yasuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
DNA損傷応答における核内構造体の動態制御機構の解析Principal Investigator
- Principal Investigator
  
  依田成玄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Molecular mechanism of DNA damage-induced responses and its failure by carcinogenesis
- Principal Investigator
  
  MINAMI Yasuhiro
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
細胞周期制御機構の破綻と悪性腫瘍
- Principal Investigator
  
  南康博
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
癌遺伝子産物・癌抑制遺伝子産物による悪性リンパ腫の放射線感受性制御機構
- Principal Investigator
  
  大石勲
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
悪性リンパ腫の放射線感受性制御におけるChk2の機能
- Principal Investigator
  
  大石勲
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
細胞周期制御機構の破綻と悪性腫瘍
- Principal Investigator
  
  MINAMI Yasuhiro
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University

All 2023 2022 2021 2020 2019 2008 2007 2006

All Journal Article Presentation Book

[Book] イラストレイテッド生化学原著4版"Lippincott's Illustrated Reviews: Biochemistry 4th ed. (石崎泰樹、丸山敬監訳)2008
- Author(s)
  西田満、依田成玄、南康博
- Publisher
  丸善(株)出版
- Data Source
  KAKENHI-PROJECT-17014062
[Book] イラストレイテッド生化学原著4版Lippincott's Illustrated Reviews : Biochemistry 4th ed2008
- Author(s)
  西田満、依田成玄、南康博(石崎泰樹、丸山敬監訳)
- Total Pages
  619
- Publisher
  丸善(株)出版
- Data Source
  KAKENHI-PROJECT-19390076
[Book] 実験医学(増刊)24巻10号 DNA損傷応答システムとその破綻による癌化2006
- Author(s)
  依田成玄
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17014062
[Journal Article] Amplified <i>EPOR</i>/<i>JAK2</i> Genes Define a Unique Subtype of Acute Erythroid Leukemia2022
- Author(s)
  Takeda J, Kenichi Y, (9人省略), Kon A (12/41番目), (途中省略), Makishima H, Ogawa S
- Journal Title
  
  Blood Cancer Discovery
  
  Volume: 3 Issue: 5 Pages: 410-427
- DOI
  10.1158/2643-3230.bcd-21-0192
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
[Journal Article] CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma.2022
- Author(s)
  Kameda T, Shide K, Kamiunten A, Kogure Y, Morishita D, Koya J, Tahira Y, Akizuki K, Yokomizo-Nakano T, Kubota S, Marutsuka K, Sekine M, Hidaka T, Kubuki Y, Kitai Y, Matsuda T, Yoda A, Ohshima T, Sugiyama M, Sashida G, Kataoka K, Ogawa S, Shimoda K.
- Journal Title
  
  Commun Biol;5(1)
  
  Volume: - Pages: 1309-1309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma2022
- Author(s)
  Takuro Kameda, ...Sho Kubota.... , Kazuya Shimoda
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1309-1309
- DOI
  10.1038/s42003-022-04284-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08421, KAKENHI-PROJECT-20K08715, KAKENHI-PROJECT-23K24079
[Journal Article] The first Japanese biobank of patient-derived pediatric acute lymphoblastic leukemia xenograft models.2022
- Author(s)
  Tanaka K, Kato I, Dobashi Y, Imai JI, Mikami T, Kubota H, Ueno H, Ito M, Ogawa S, Nakahata T, Takita J, Toyoda H, Ogawa C, Adachi S, Watanabe S, Goto H.
- Journal Title
  
  Cancer Sci
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes2020
- Author(s)
  Ochi Y, Ogawa Seishi., et al.
- Journal Title
  
  Cancer Discov
  
  Volume: - Issue: 6 Pages: 836-853
- DOI
  10.1158/2159-8290.cd-19-0982
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05976, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-19H03560, KAKENHI-PROJECT-17J05245, KAKENHI-INTERNATIONAL-15K21761, KAKENHI-PROJECT-20K21546, KAKENHI-PLANNED-16H06484, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-18K16084, KAKENHI-PROJECT-19K24694, KAKENHI-PROJECT-19H03694
[Journal Article] Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions2020
- Author(s)
  Noriaki Yoshida, Kay Shigemori, Nicholas Donaldson, Christopher Trevisani, Nicolas A Cordero, Kristen E Stevenson, Xia Bu, Fumiko Arakawa, Mai Takeuchi, Koichi Ohshima, Akinori Yoda, Samuel Y Ng , David M Weinstock
- Journal Title
  
  Blood
  
  Volume: 135 Issue: 17 Pages: 1467-1471
- DOI
  10.1182/blood.2019001815
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16574, KAKENHI-PROJECT-17K08751, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-19H03560
[Journal Article] Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.2008
- Author(s)
  Yoda, A., Toyoshima, K., Watanabe, Y., Onishi, N., Hasaka, Y., Tsukuda, Y., Tsukada, J., Kondo, T., Tanaka, Y., Minami, Y.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 18969-18979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014062
[Journal Article] Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.2007
- Author(s)
  Kani, S., Nakayama, E., Yoda, A., Onishi, N., Sougawa, N., Hazaka, Y., Umeda, T., Takeda, K., Ichijo, H., Hamada, Y., Minami, Y.
- Journal Title
  
  Genes Cells 12
  
  Pages: 919-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014062
[Journal Article] Intrinsic kinase activity and SQ/TQ cluster domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.2006
- Author(s)
  Yoda, A.
- Journal Title
  
  J. Biol. Chem. 281 巻
  
  Pages: 24847-24862
- Data Source
  KAKENHI-PROJECT-17014062
[Journal Article] DNA損傷応答システムとその破綻による癌化2006
- Author(s)
  依田成玄
- Journal Title
  
  実験医学 24・10
  
  Pages: 1408-1415
- Data Source
  KAKENHI-PROJECT-18790222
[Journal Article] Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.2006
- Author(s)
  Yoda, A.
- Journal Title
  
  J. Biol. Chem. 281・34
  
  Pages: 24847-24862
- Data Source
  KAKENHI-PROJECT-18790222
[Journal Article] Intrinsic kinase activity and SQ/TQ cluster domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip12006
- Author(s)
  Yoda, A., Xu, X.Z., Fujimoto, H., Kato, N., Onishi, N., Oishi, I., Minami, Y.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 24847-24862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014062
[Journal Article] Regulation of the anti-oncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.2006
- Author(s)
  Fujimoto, H., Onishi, N., Kato, N., Takekawa, M., Xu, X.Z., Kosugi, A., Kondo, T., Oishi, I., Yoda, A., Imamura, M., Minami, Y.
- Journal Title
  
  Cell Death Differ. 13
  
  Pages: 1170-1180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014062
[Presentation] CTX-712, a novel splicing inhibitor targeting myeloid neoplasms2023
- Author(s)
  Akinori Yoda1, Daisuke Morishita3, Yotaro Ochi1, Akio Mizutani3, Takuto Mori1, June Takeda1, Hirokazu Tozaki3, Yoshihiko Satoh3, Hideki Makishima1, Masahiro Nakagawa1, Yasuhito Nannya1, Seishi Ogawa1,2
- Organizer
  第13回JSH国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] CTX-712, a novel splicing inhibitor targeting myeloid neoplasms2023
- Author(s)
  Akinori Yoda1, Daisuke Morishita3, Yotaro Ochi1, Akio Mizutani3, Takuto Mori1, June Takeda1, Hirokazu Tozaki3, Yoshihiko Satoh3, Hideki Makishima1, Masahiro Nakagawa1, Yasuhito Nannya1, Seishi Ogawa1,2
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] DISTINCT PATHOGENESIS OF CLONAL HEMATOPOIESIS REVEALED BY SINGLE-CELL MULTI-OMICS SEQUENCING.2023
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, Masanori Motomura, June Takeda, Xingxing Qi, Koji Okazaki, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  MDS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel splicing inhibitor targeting myeloid neoplasms2023
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, Takuto Mori, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Hideki Makishima, Masahiro Nakagawa, Yasuhito Nannya, Seishi Ogawa
- Organizer
  the 17th International Congress on Myelodysplastic Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method.2022
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] 64th ASH Annual Meeting and Exposition2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  CTX-712, a novel splicing modulator targeting myeloid neoplasms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] CTX-712, a novel splicing modulator targeting myeloid neoplasms2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] 第84回日本血液学会学術集会2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  CTX-712, a novel splicing modulator targeting myeloid neoplasms
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] CTX-712, a novel splicing modulator targeting myeloid neoplasms2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  American Association for Cancer Research Annual Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell multi-omics sequencing.2022
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Ryunosuke Saiki, Yotaro Ochi, June Takeda, Zhao Lanying, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel splicing modulator targeting myeloid neoplasms2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] 第81回日本癌学会学術総会2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  CTX-712, a novel splicing modulator targeting myeloid neoplasms
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] CTX-712, a novel splicing modulator targeting myeloid neoplasms2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell multi-omics sequencing.2022
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Ryunosuke Saiki, Yotaro Ochi, June Takeda, Zhao Lanying, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel splicing modulator targeting myeloid neoplasms2022
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  American Association for Cancer Research Annual Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24079
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2021
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  63rd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2021
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  The 83rd Annual Meeting of the Japanese_Cancer_Association
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell sequencing.2021
- Author(s)
  Masahiro M Nakagawa12, Ryosaku Inagaki123, Yutaka Kuroda4, Yasuhito Nannya1, Zhao Lanying15, Yotaro Ochi1, June Takeda1, Xingxing Qi1, Akinori Yoda1, Ayana Kon1, Tetsuichi Yoshizato6, Nobuyuki Kakiuchi1, Hideki Makishima1, Shuichi Matsuda4 and Seishi Ogawa156
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2021
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2021
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  63rd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03560
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2021
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03560
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2021
- Author(s)
  Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  第80回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03560
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method.2021
- Author(s)
  Masahiro M Nakagawa1, Ryosaku Inagaki12, Yutaka Kuroda4, Yasuhito Nannya1, Lanying Zhao15, Yotaro Ochi1, June Takeda1, Xingxing Qi1, Akinori Yoda1, Ayana Kon1, Nobuyuki Kakiuchi1, Hideki Makishima1, Shuichi Matsuda3 and Seishi Ogawa145
- Organizer
  63rd ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Non-cell autonomous effects of mutated cells in the pathogenesis of clonal hematopoiesis.2021
- Author(s)
  Masahiro M Nakagawa12, Ryosaku Inagaki123, Yasuhito Nannya1, Zhao Lanying15, Yotaro Ochi1, June Takeda1, Xingxing Qi1, Akinori Yoda1, Ayana Kon1, Tetsuichi Yoshizato6, Nobuyuki Kakiuchi1, Hideki Makishima1, Shuichi Matsuda4 and Seishi Ogawa156
- Organizer
  The 80th Annual Meeting of the Japanese_Society of_Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2020
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Yotaro Ochi, Hirokazu Tozaki, Yoshihiko Satoh, June Takeda, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  The 82nd Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  62nd ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Early Clonal evolution of myeloid malignancies.2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of MDS and AML by single-cell DNA/RNA sequencing2020
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Zhao Lanying, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  The 82nd Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of MDS and AML by single-cell DNA/RNA2020
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, June Takeda, Akinori Yoda, Ayana Kon, Hideki Makishima, Seishi Ogawa
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by high throughput single cell RNA sequencing integrated with highly sensitive genotyping method2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  25th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of Clonal Evolution of AML Using Simultaneous Single-cell DNA/RNA Analysis2020
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Lanying Zhao, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  the 62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2020
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Yotaro Ochi, Hirokazu Tozaki, Yoshihiko Satoh, June Takeda, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PUBLICLY-19H04806
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2020
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Yotaro Ochi, Hirokazu Tozaki, Yoshihiko Satoh, June Takeda, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PUBLICLY-19H04806
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2020
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Yotaro Ochi, Hirokazu Tozaki, Yoshihiko Satoh, June Takeda, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2020
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Yotaro Ochi, Hirokazu Tozaki, Yoshihiko Satoh, June Takeda, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03560
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with SRSF2 mutation2020
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Yotaro Ochi, Hirokazu Tozaki, Yoshihiko Satoh, June Takeda, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PROJECT-19H03560
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell RNA/DNA sequencing2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第82回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution in MDS to sAML transformation by single-cell sequencing2019
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, June Takeda, Akinori Yoda, Ayana Kon, Hideki Makishima, Seishi Ogawa
- Organizer
  The 78th JCA conference
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation2019
- Author(s)
  Akinori Yoda
- Organizer
  62th American Society of Hematology (ASH) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03560
[Presentation] Analysis of mechanisms underlying clonal evolution of AML by a new single-cell sequencing platform2019
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Lanying Zhao, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  62nd American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of AML by a new single-cell sequencing platform2019
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Zhao Lanying, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  The 81st JCA conference 2019, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a novel CLK inhibitor targeting myeloid neoplasms with splicing factor mutations (Oral)2019
- Author(s)
  Akinori Yoda, Daisuke Morishita, Akio Mizutani, Hirokazu Tozaki, Yotaro Ochi, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake and Seishi Ogawa
- Organizer
  The 61st Annual Meeting and Exposition of American Society of Hematology, Orlando, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation2019
- Author(s)
  Akinori Yoda
- Organizer
  62th American Society of Hematology (ASH) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04806
[Presentation] 潰瘍性大腸炎における上皮細胞の陽性選択2019
- Author(s)
  垣内伸之, 内野基, 木原多佳子, 赤木宏太朗, 井上善景, 長山聡, 横山顕礼, 平野智紀, 竹内康英, 越智陽太郎, 塩澤裕介, 片岡圭亮, 中川正宏, 依田成玄, 南谷泰仁, 牧島秀樹, 白石友一, 千葉健一, 真田昌, 三好弘之, 坂井義治, 桜井孝規, 羽賀博典, 廣田誠一, 池内浩基, 竹内理, 宮野悟, 妹尾浩, 小川誠司
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Chk1/Chk2 phosphorylates and stabilizes Wip1 in response to DNA damage2007
- Author(s)
  大西伸幸、依田成玄、近藤健、南康博
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-17014062

1. MINAMI Yasuhiro (70229772)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. 大石勲 (50314472)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. NISHITA MICHIRU (30379359)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. ENDO MITSUHARU (90436444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMAGATA KAORU (80533786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Ogawa Seishi (60292900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
7. 寒川延子 (30432579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中川正宏 (10431850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
9. 片岡竜貴 (20343254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 昆彩奈 (20772403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
11. 牧島秀樹 (40402127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
12. 南谷泰仁 (60451811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
13. 江藤正俊 (90315078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 竹田淳恵 (20901276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
15. 久保田翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉田稚明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoda Akinori 依田 成玄

YODA AKINORI 依田 成玄

Research Projects

Research Products

Co-Researchers

PDX models of rare hematopoietic malignancies for novel cancer therapiesPrincipal Investigator

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Cancer immunotherapy targeting neo-self antigens in splicing factor mutated cellsPrincipal Investigator

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comprehensive studies on the molecular basis of early development and clonal evolution in cancer using advanced genomics.

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Development of diagnosis and treatment of novel drug targets using refractory leukemia modelsPrincipal Investigator

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がん遺伝子産物Wip1ホスファターゼによるDNA損傷応答制御Principal Investigator

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Analysis of regulatory mechanisms for cell migration and cell polarity by Wnt5a and Ror2 receptor tyrosine kinase

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DNA損傷応答における核内構造体の動態制御機構の解析Principal Investigator

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Molecular mechanism of DNA damage-induced responses and its failure by carcinogenesis

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細胞周期制御機構の破綻と悪性腫瘍

Principal Investigator

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癌遺伝子産物・癌抑制遺伝子産物による悪性リンパ腫の放射線感受性制御機構

Principal Investigator

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悪性リンパ腫の放射線感受性制御におけるChk2の機能

Principal Investigator

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Research Institution

細胞周期制御機構の破綻と悪性腫瘍

Principal Investigator

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Review Section

Research Institution

[Book] イラストレイテッド生化学原著4版"Lippincott's Illustrated Reviews: Biochemistry 4th ed. (石崎泰樹、丸山敬 監訳)2008

Author(s)

Publisher

Yoda Akinori 依田成玄

YODA AKINORI 依田成玄

[Book] イラストレイテッド生化学原著4版"Lippincott's Illustrated Reviews: Biochemistry 4th ed. (石崎泰樹、丸山敬監訳)2008