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(nishikawa) (takesi)  西川 武志

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… Alternative Names

NISHIKAWA Takeshi  西川 武志

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Researcher Number 70336212
Other IDs
External Links
Affiliation (Current) 2025: 独立行政法人国立病院機構熊本医療センター(臨床研究部), 独立行政法人国立病院機構熊本医療センター(臨床研究部), 診療科医長
Affiliation (based on the past Project Information) *help 2016 – 2017: 熊本大学, 大学院生命科学研究部(医), 特任准教授
2016: 独立行政法人国立病院機構熊本医療センター(臨床研究部), 独立行政法人国立病院機構熊本医療センター(臨床研究部), 診療科医長
2015: 独立行政法人国立病院機構熊本医療センター(臨床研究部), その他部局等, その他
2014: 熊本大学, 大学院生命科学研究部, 特任教授
2014: 熊本大学, 生命科学研究部, 特任教授 … More
2013: 熊本大学, 大学院生命科学研究部(医), 准教授
2012 – 2013: 熊本大学, 大学院生命科学研究部, 准教授
2012 – 2013: 熊本大学, 生命科学研究部, 准教授
2012: 熊本大学, その他の研究科, 准教授
2011: 熊本大学, 大学院生命科学研究部, 特任准教授
2010 – 2011: Kumamoto University, 大学院・生命科学研究部, 特任准教授
2009: Kumamoto University, 大学院・生命科学研究部, 講師
2008: 熊本大学, 医学部・附属病院, 助教
2008: Kumamoto University, 大学院・医学薬学研究部, 講師
2007 – 2008: Kumamoto University, Faculty of Medical and Phamaceutical sciences, Assistant Professor
2005 – 2006: 熊本大学, 大学院医学薬学研究部, 助手
2003 – 2005: Kumamoto University, Department of Medicine, Investigator, 大学院・医学薬学研究部, 助手
2001 – 2002: 熊本大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Metabolomics / Metabolomics
Except Principal Investigator
Metabolomics / Metabolomics / Biomedical engineering/Biological material science / Biological Sciences
Keywords
Principal Investigator
活性酸素 / ミトコンドリア / 糖尿病 / MnSOD / 糖尿病合併症 / 酸化ストレス / Oxidative stress / Mitochondria / Diabetic complications / Diabetes Mellitus … More / PGC-1α / AMPK / PPARγアゴニスト / PPARγ / eNOS / Mitochondria biogenesis / ミトコンドリアバイオジェネシス / NUCLEAR FACTOR κB / CYCLOOXYGENASE-2 / REACTIVE OXYGENSPECIES / OXIDATIVE STRESS / MITOCHONDRIA / GLOMERULAR HYPERFILTRATION / DIABETIC NEPHROPATHY / DIABETS NELLITUS / プロスタグランジンE_2 / NFκB / シクロオキシゲナーゼ2 / 糸球体過剰濾過 / 糖尿病性腎症 / グルカゴン / DNA傷害 / 組織低酸素 / メタボリックシンドローム / MnSODA / 糖代謝異常 / エネルギー … More
Except Principal Investigator
糖尿病 / インスリン抵抗性 / 脂肪細胞 / CHOP / 肥満 / 酸化ストレス / 動脈硬化 / マクロファージ / β酸化 / ミトコンドリアROS / 糖尿病網膜症 / 糖尿病細小血管合併症 / 低血糖 / ミトコンドリア由来活性酸素種 / Hepatic glucose uptake / Compartment model / Closed-loop insulin infusion algorithm / Intraportal insulin infusion / Artificial endocrine pancreas / net hepatic glucose balance / 肝糖取り込み / コンパートメントモデル / インスリン注入アルゴリズム / 門脈内インスリン注入 / 人工膵島 / pancreatic β-cell / OLETF rat / Akita mouse / Diabetes mellitus / Apoptosis / Endoplasmic reticulum stress / MIN6 / 膵β細胞 / OLETFラット / Akitaマウス / アポトーシス / 小胞体ストレス / Manganese superoxide dismutase / 8-hydroxydeoxyguanosine / Mitochondria / Oxidative stress / Diabetic complications / 活性酸素 / 血管合併症 / トランスジェニックマウス / マンガネーゼスーパーオキサイドジスムターゼ / 8-ハイドロキシデオキシグアノシン / ミトコンドリア / 糖尿病性合併症 / 2型糖尿病発症 / ADAM-8 / TNF1型受容体 / 2型糖尿病 / メタボリックシンドローム / サイトカイン / 炎症 / TNF-R1 / 蛋白質 / シグナル伝達 / 細胞・組織 / 発現制御 / TNFa産生 / インスリンシグナル伝達 / ストレスキナーゼ / TNFa 変換酵素(TACE) / 脂肪組織 / 糖尿病合併症 / MnSOD / 脂肪 / 糖尿病学 / cPLA2 / COX-2 / PPARγ / cPLA_2 / AICAR / インスリン受容体 / IRS-1 / インスリン Less
  • Research Projects

    (15 results)
  • Research Products

    (195 results)
  • Co-Researchers

    (11 People)
  •  Involvement of mtROS and Warburg effect in diabetic complications progression mechanism by hypoglycemia

    • Principal Investigator
      Kukidome Daisuke
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Role of mitochondrial ROS generation in the development of diabetic complicationsPrincipal Investigator

    • Principal Investigator
      Nishikawa Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Department of Clinical Research, Nationai Hospital Organization Kumamoto Medical Center
      Kumamoto University
  •  Shedding of TNF receptors in adipose tissues and insulin resistance

    • Principal Investigator
      MOTOSHIMA HIROYUKI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Involvement of mitochondrial ROS in the pathogenesis of diabetic complicationsPrincipal Investigator

    • Principal Investigator
      NISHIKAWA Takeshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  TNFa変換酵素を介したインスリン抵抗性発現機序の解析

    • Principal Investigator
      MOTOSHIMA Hiroyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Impact of mitochondrial reactive oxygen species in the pathogenesis of diabetic nephropathyPrincipal Investigator

    • Principal Investigator
      NISHIKAWA Takeshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Effect of cPLA_2 inhibition on improvement of glucose tolerance through PPARγ activation

    • Principal Investigator
      MATSUMURA Takeshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Role of reactive oxygen species in white and brown adipose tissuesin pathogenesis of insulin resistance

    • Principal Investigator
      TSURUZOE Kaku
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Impact of mitochondria reactive oxygen species in the pathogenesis of diabetic macro- and micro vascular complications.Principal Investigator

    • Principal Investigator
      NISHIKAWA Takeshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  脂肪細胞におけるインスリン作用伝達分子の発現調節と生体機能制御における意義

    • Principal Investigator
      ARAKI Eiichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Activation of AMPK reduces hyperglycemia-induced mitochondrial ROS production and promotion of mitochondrial biogenesis.Principal Investigator

    • Principal Investigator
      NISHIKAWA Takeshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Development of closed-loop intraportal insulin infusion algorithm

    • Principal Investigator
      NISHIDA Kenro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kumamoto University
  •  New pathogenesis of diabetes mellitus : Role of endoplasmic reticulum stress mediated apoptosis on pancreatic β-cells

    • Principal Investigator
      ARAKI Eiichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  REACTIVE OXYGEN SPECIES FROM MITOCHONDRIA INDUCE CYCLOOXYGENASE-2 GENE EXPRESSION IN HUMAN MESANGIAL CELLS : POTENTIAL ROLE IN DIABETIC NEPHROPATHYPrincipal Investigator

    • Principal Investigator
      NISHIKAWA Takeshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  The role of mitochondria-derived reactive oxygen species in the pathogenesis of diabetic complications

    • Principal Investigator
      TOYONAGA Tetsushi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Diabetes Frontier2017

    • Author(s)
      久木留大介、梶原伸宏、西川武志、荒木栄一
    • Total Pages
      8
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-15K09393
  • [Journal Article] Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells.2017

    • Author(s)
      Kajihara N, Kukidome D, Sada K, Motoshima H, Furukawa N, Matsumura T, Nishikawa T, Araki E
    • Journal Title

      Journal of diabetes investigation

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells.2017

    • Author(s)
      Kajihara N, Kukidome D, Sada K, Motoshima H, Furukawa N, Matsumura T, Nishikawa T, Araki E.
    • Journal Title

      J Diabetes Investig.

      Volume: 印刷中 Issue: 6 Pages: 750-761

    • DOI

      10.1111/jdi.12678

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09393, KAKENHI-PROJECT-16K09759, KAKENHI-PROJECT-15K15348, KAKENHI-PROJECT-16K09787, KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-15K09394
  • [Journal Article] Involvement of advanced glycation end products in “hyperglycemic memory”.2016

    • Author(s)
      Nishikawa T, Araki E
    • Journal Title

      J Diabetes Invest

      Volume: 7 Issue: 3 Pages: 297-299

    • DOI

      10.1111/jdi.12405

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice2016

    • Author(s)
      Hanatani S, Motoshima H, Takaki Y, Kawasaki S, Igata M, Matsumura T, Kondo T, Senokuchi T, Ishii N, Kawashima J, Kukidome D, Shimoda S, Nishikawa T, Araki E
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 59 Issue: 3 Pages: 207-214

    • DOI

      10.3164/jcbn.16-23

    • NAID

      130005268723

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461340, KAKENHI-PROJECT-15K19519
  • [Journal Article] ミトコンドリア由来活性酸素2016

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Journal Title

      日本臨床

      Volume: 74 Pages: 67-72

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] Measurement of small-fiber pain threshold values for the early detection of diabetic polyneuropathy.2016

    • Author(s)
      Kukidome D, Nishikawa T, Sato M, Igata M, Kawashima J, Shimoda S, Matsui K, Obayashi K, Ando Y, Araki E.
    • Journal Title

      Diabet Med

      Volume: 33 Issue: 1 Pages: 62-69

    • DOI

      10.1111/dme.12797

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08620, KAKENHI-PROJECT-26461340
  • [Journal Article] 糖尿病合併症の疾患概念と分類2016

    • Author(s)
      西川武志
    • Journal Title

      日本臨床

      Volume: 74 Pages: 9-14

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] Hyperglycemia Induces Cellular Hypoxia through Production of Mitochondrial ROS Followed by Suppression of Aquaporin-1.2016

    • Author(s)
      Sada K, Nishikawa T, Kukidome D, Yoshinaga T, Kajihara N, Sonoda K, Senokuchi1 T, Motoshima H, Matsumura T, Araki E
    • Journal Title

      PLoS ONE

      Volume: 11 Issue: 7 Pages: e0158619-e0158619

    • DOI

      10.1371/journal.pone.0158619

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461340, KAKENHI-PROJECT-16K09759, KAKENHI-PROJECT-15K15348
  • [Journal Article] 糖尿病合併症をいかに防ぐか 予防のエビデンスと戦略2015

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      診断と治療

      Volume: 103 Pages: 290-296

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] 糖尿病合併症をいかに防ぐか 予防のエビデンスと戦略.2015

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      診断と治療

      Volume: 103 Pages: 290-295

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] 抗酸化療法による糖尿病合併症治療の現在と未来2014

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Journal Title

      日本体質医学会

      Volume: 76 Pages: 16-21

    • NAID

      40020028708

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation.2014

    • Author(s)
      Fukuda K, Matsumura T, Senokuchi T, Ishii N, Kinoshita H, Yamada S, Murakami S, Nakao S, Motoshima H, Kondo T, Kukidome D, Kawasaki S, Kawada T, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 457 Issue: 1 Pages: 23-20

    • DOI

      10.1016/j.bbrc.2014.12.063

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461361, KAKENHI-PROJECT-26461340, KAKENHI-PROJECT-25461360, KAKENHI-PROJECT-25461374
  • [Journal Article] 合併症はなぜ起こる2014

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      糖尿病診療マスター

      Volume: 12 Pages: 236-239

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] 合併症はなぜ起こる2014

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      糖尿病診療マスター

      Volume: 12 Pages: 236-239

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] 個別化医療をめざした血糖コントロール目標―「熊本宣言」の実践をめざし―2014

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      プラクティス

      Volume: 31 Pages: 43-50

    • Data Source
      KAKENHI-PROJECT-26461340
  • [Journal Article] Mitochondrial reactive oxygen species in the pathogenesis of early diabetic nephropathy.2014

    • Author(s)
      Nishikawa T, Brownlee M, Araki E
    • Journal Title

      J Diabetes Invest

      Volume: 6 Issue: 2 Pages: 137-139

    • DOI

      10.1111/jdi.12258

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-26461340
  • [Journal Article] 抗酸化療法による糖尿病合併症治療の現在と未来2014

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Journal Title

      日本体質医学会

      Volume: 76 Pages: 16-21

    • NAID

      40020028708

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] 個別化医療をめざした血糖コントロール目標―「熊本宣言」の実践をめざし―2014

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      プラクティス

      Volume: 31 Pages: 43-50

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] 糖尿病大血管障害の治療戦略2013

    • Author(s)
      横手幸太郎, 庄司哲雄, 西川武志, 南野徹
    • Journal Title

      Diabetes Update

      Volume: 2 Pages: 142-153

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages2013

    • Author(s)
      木下博之
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 431 Issue: 2 Pages: 124-130

    • DOI

      10.1016/j.bbrc.2013.01.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590987, KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23591312, KAKENHI-PROJECT-23591337, KAKENHI-PROJECT-23791038, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461374
  • [Journal Article] 酸化ストレス.2013

    • Author(s)
      西川武志, 久木留大介, 佐田公範, 荒木栄一
    • Journal Title

      糖尿病性神経障害 基礎から臨床のすべて

      Volume: - Pages: 72-77

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice2013

    • Author(s)
      川崎修二
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 430 Issue: 4 Pages: 1189-1194

    • DOI

      10.1016/j.bbrc.2012.12.086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590987, KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23591312, KAKENHI-PROJECT-23791038, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461374
  • [Journal Article] Relationship between lifestyle and lifestyle-related factors in a rural–urban population of Japan2013

    • Author(s)
      Zhang SC, Wei CN, Harada K, Ueda K, Fukumoto K, Matsuo H, Minamoto K, Nishikawa T, Araki E, Ueda A, Fang J
    • Journal Title

      Environ Health Prev Med

      Volume: 18 Pages: 267-274

    • NAID

      10031189203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] 糖尿病合併症の環境因子と体質2013

    • Author(s)
      西川武志, 荒木栄一
    • Journal Title

      日本体質医学会

      Volume: 75 Pages: 146-151

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Mechanism-based antioxidant therapies promise to prevent diabetic complications?2013

    • Author(s)
      Nishikawa T, Araki E
    • Journal Title

      J Diabetes Invest

      Volume: 4 Pages: 105-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Regulation of TNFαconverting enzyme activity in visceral adipose tissue of obese mice2013

    • Author(s)
      Kawasaki S, Motoshima H, Hanatani S,Takaki Y, Igata M, Tsutsumi A, Matsumura T, Kondo T, Senokuchi T, Ishii N, Kinoshita H, Fukuda K, Kawashima J, Shimoda S, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 430 Pages: 1189-1194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages2013

    • Author(s)
      Kinoshita H, Matsumura T, Ishii N, Fukuda K, Senokuchi T, Motoshima H, Kondo T, Taketa K, Kawasaki S, Hanatani S, Takeya M, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 431 Pages: 124-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Regulation of TNFαconverting enzyme activity invisceral adipose tissue of obese mice2013

    • Author(s)
      Kawasaki S, Motoshima H, Hanatani S,Takaki Y, Igata M, Tsutsumi A,Matsumura T, Kondo T, Senokuchi T,Ishii N, Kinoshita H, Fukuda K,Kawashima J, Shimoda S, NishikawaT, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 430 Pages: 1189-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590987
  • [Journal Article] 糖尿病における酸化ストレス制御異常2013

    • Author(s)
      久木留大介, 西川武志, 荒木栄一
    • Journal Title

      医学のあゆみ

      Volume: 247 Pages: 915-920

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Apocynin suppresses theprogression of atherosclerosis inapoE-deficient mice by inactivationof macrophages2013

    • Author(s)
      Kinoshita H, Matsumura T, Ishii N,Fukuda K, Senokuchi T, Motoshima H,Kondo T, Taketa K, Kawasaki S,Hanatani S, Takeya M, Nishikawa T,Araki E
    • Journal Title

      Biochem Biophys ResCommun

      Volume: 431 Pages: 124-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590987
  • [Journal Article] Relationship between lifestyle and lifestyle-related factors in a rural-urban population of Japan.2013

    • Author(s)
      Zhang SC, Wei CN, Harada K, Ueda K, Fukumoto K, Matsuo H, Minamoto K, Nishikawa T, Araki E, Ueda A, Fang J
    • Journal Title

      Environ Health Prev Med

      Volume: 18 Issue: 4 Pages: 267-274

    • DOI

      10.1007/s12199-012-0315-5

    • NAID

      10031189203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23591312, KAKENHI-PROJECT-24591336
  • [Journal Article] Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes.2013

    • Author(s)
      Matsumura T, Taketa K, Motoshima H, Senokuchi T, Ishii N, Kinoshita H, Fukuda K, Yamada S, Kukidome D, Kondo T, Hisada A, Katoh T, Shimoda S, Nishikawa T, Araki E.
    • Journal Title

      Cardiovascular Diabetology

      Volume: 12(1) Issue: 1 Pages: 177-177

    • DOI

      10.1186/1475-2840-12-177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23591312, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461374
  • [Journal Article] レニン・アンギオテンシン系(RAS)を使った網膜症抑制2012

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Journal Title

      medicina

      Volume: 49 Pages: 876-879

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] 酸化ストレス2012

    • Author(s)
      西川武志、久木留大介、佐田公範、荒木栄一
    • Journal Title

      糖尿病網膜症のすべて

      Volume: - Pages: 72-77

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] 糖尿病網膜症に対する新規治療法の開発動向2012

    • Author(s)
      西川武志, 後藤秀生, 佐田公範, 久木留大介, 荒木栄一
    • Journal Title

      日本臨床

      Volume: 70(Suppl 5) Pages: 369-373

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] HbA1cの目標値はどのように設定すべきか2012

    • Author(s)
      植木浩二郎, 傍島裕司, 西川武志, 西村理明, 久木留大介, 柴田大河, 辻野大助
    • Journal Title

      Diabetes Strategy

      Volume: 2 Pages: 169-185

    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] An intervention study to promote self-improvement of lifestyle in a Japanese community: a new health support program.2011

    • Author(s)
      Fukumoto K, Wei CN, Matsuo H, Harada K, Zhang SC, Kalay L, Yamashiro T, Nishikawa T, Araki E, Ueda A
    • Journal Title

      Environ Health Prev Med

      Volume: 16 Issue: 4 Pages: 253-263

    • DOI

      10.1007/s12199-010-0194-6

    • NAID

      10029520598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] An intervention study to promote self-improvement of lifestyle in a Japanese community : a new health support program.2011

    • Author(s)
      Fukumoto K, Nishikawa T, et al.
    • Journal Title

      Environ Health Prev Med

      Volume: (In press)

    • NAID

      10029520598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Telmisartan Exerts Antiatherosclerotic Effects by Activating Peroxisome Proliferator-Activated Receptor-{gamma} in Macrophages.2011

    • Author(s)
      Matsumura T, Kinoshita H, Ishii N, Fukuda K, Motoshima H, Senokuchi T, Taketa K, Kawasaki S, Nishimaki-Mogami T, Kawada T, Nishikawa T, Araki E
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31 Issue: 6 Pages: 1268-1275

    • DOI

      10.1161/atvbaha.110.222067

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312, KAKENHI-PROJECT-23791038
  • [Journal Article] Caloricrestriction decreases ER stress inliver and adipose tissue in ob/ob mice2011

    • Author(s)
      Tsutsumi A, Motoshima H, Kondo T,Kawasaki S, Matsumura T, Hanatani S,Igata M, Ishii N, Kinoshita H, KawashimaJ, Taketa K, Furukawa N, Tsuruzoe K,Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404 Pages: 339-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590987
  • [Journal Article] Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice2011

    • Author(s)
      Tsutsumi A, Motoshima H, Kondo T, Kawasaki S, Matsumura T, Hanatani S, Igata M, Ishii N, Kinoshita H, Kawashima J, Taketa K, Furukawa N, Tsuruzoe K, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404 Pages: 339-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] An intervention study to promote self-improvement of lifestyle in a Japanese community : a new health support program2011

    • Author(s)
      Fukumoto K, Wei CN, Matsuo H, Harada K, Zhang SC, Kalay L, Yamashiro T, Nishikawa T, Araki E, Ueda A
    • Journal Title

      Environ Health Prev Med

      Volume: 16 Pages: 253-263

    • NAID

      10029520598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] An intervention study to promote self-improvement of lifestyle in a Japanese community : a new health support program.2011

    • Author(s)
      Fukumoto K, Wei CN, Matsuo H, Harada K, Zhang SC, Kalay L, Yamashiro T, Nishikawa T, Araki E, Ueda A
    • Journal Title

      Environ Health Prev Med in press

    • NAID

      10029520598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Telmisartan Exerts Antiatherosclerotic Effects by Activating Peroxisome Proliferator-Activated Receptor-{gamma} in Macrophages.2011

    • Author(s)
      Matsumura T, Nishikawa T, et al.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Telmisartan Exerts Antiatherosclerotic Effects by Activating Peroxisome Proliferator-Activated Receptor-γ in Macrophages.2011

    • Author(s)
      Matsumura T, Kinoshita H, Ishii N, Fukuda K, Motoshima H, Senokuchi T, Taketa K, Kawasaki S, Nishimaki-Mogami T, Kawada T, Nishikawa T, Araki E
    • Journal Title

      Arterioscler Thromb Vasc Biol in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Telmisartan Exerts Antiatherosclerotic Effects by Activating Peroxisome Proliferator-Activated Receptor-γin Macrophages2011

    • Author(s)
      Matsumura T, Kinoshita H, Ishii N, Fukuda K, Motoshima H, Senokuchi T, Taketa K, Kawasaki S, Nishimaki-Mogami T, Kawada T, Nishikawa T, Araki E
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31 Pages: 1268-1275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Telmisartan exerts antiatheroscleroticeffects by activating peroxisomeproliferator-activated receptor-r inmacrophages2011

    • Author(s)
      Matsumura T, Kinoshita H, Ishii N,Fukuda K, Motoshima H, Senokuchi T,Take ta K, Ka was aki S, N ish im aki- Mog ami T,Kawada T, Nishikawa T, Araki E
    • Journal Title

      Arterioscler Thromb VascBiol

      Volume: 31 Pages: 1268-1275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590987
  • [Journal Article] Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice.2011

    • Author(s)
      Tsutsumi A, Nishikawa T, et al.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404 Pages: 339-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice.2011

    • Author(s)
      Tsutsumi A, Motoshima H, Kondo T, Kawasaki S, Matsumura T, Hanatani S, Igata M, Ishii N, Kinoshita H, Kawashima J, Taketa K, Furukawa N, Tsuruzoe K, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404 Issue: 1 Pages: 339-344

    • DOI

      10.1016/j.bbrc.2010.11.120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice.2011

    • Author(s)
      Tsutsumi A, Motoshima H, Kondo T, Kawasaki S, Matsumura T, Hanatani S, Igata M, Ishii N, Kinoshita H, Kawashima J, Taketa K, Furukawa N, Tsuruzoe K, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun 404

      Pages: 339-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.2010

    • Author(s)
      Ishii N, Matsumura T, Kinoshita H, Fukuda K, Motoshima H, Senokuchi T, Nakao S, Tsutsumi A, Kim-Mitsuyama S, Kawada T, Takeya M, Miyamura N, Nishikawa T, Araki E
    • Journal Title

      Arterioscler Thromb Vasc Biol 30

      Pages: 1598-1605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] The effect of group-based lifestyle interventions on risk factors and insulin resistance in subjects at risk for metabolic syndrome : The Tabaruzaka Study 1.2010

    • Author(s)
      Yamashiro T, Nishikawa T, et al.
    • Journal Title

      Diabetes Obes.Metab.

      Volume: 12 Pages: 790-797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] The effect of group-based lifestyle interventions on risk factors and insulin resistance in subjects at risk for metabolic syndrome : The Tabaruzaka Study 1.2010

    • Author(s)
      Yamashiro T, Nishikawa T, Isami S, Wei C, Fukumoto K, Matsuo H, Yoshinaga T, Kukidom D, Motoshima H, Matsumura T, Ueda A, Araki E
    • Journal Title

      Diabetes Obes.Metab. 12

      Pages: 790-797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.2010

    • Author(s)
      Ishii N, Nishikawa T, et al.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 30 Pages: 1598-1605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Oxidative stress : A cause and therapeutic target of diabetic complications.2010

    • Author(s)
      Araki E, Nishikawa T
    • Journal Title

      Journal of Diabetes Investigation 1

      Pages: 90-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Activation of AMP-activated protein kinase suppresses oxidised low-density lipoprotein-induced macrophage proliferation.2009

    • Author(s)
      Ishii N, Matsumura T, Kinoshita H, Motoshima H, Kojima K, Tsutsumi A, Kawasaki S, Yano M, Senokuchi T, Asano T, Nishikawa T, Araki E
    • Journal Title

      J Biol Cbem 284

      Pages: 34561-34569

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Activation of AMP-activated protein kinase suppresses oxidised low-density lipoprotein-induced macrophage proliferation2009

    • Author(s)
      Ishii N, Nishikawa T, et al
    • Journal Title

      Journal of Biological Chemistry 284

      Pages: 34561-34569

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Angptl 4 deficiencyimproves lipid metabolism, suppresses foamcell formation and protects against atherosclerosis2009

    • Author(s)
      Adachi H, Fujiwara Y, Kondo T, Nishikawa T, Ogawa R, Matsumura T, Ishii N, Nagai R, Miyata K, Tabata M, Motoshima H, Furukawa N, Tsuruzoe K, Kawashima J, Takeya M, Yamashita S, Koh GY, Nagy A, Suda T, Oike Y, Araki E.
    • Journal Title

      Biochem Biophys Res Commun 379

      Pages: 806-811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591059
  • [Journal Article] Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis.2009

    • Author(s)
      Adachi H, Fujiwara Y, Kondo T, Nishikawa T, Ogawa R, Matsumura T, Ishii N, Nagai R, Miyata K, Tabata M, Motoshima H, Furukawa N, Tsuruzoe K, Kawashima J, Takeya M, Yamashita S, Koh GY, Nagy A, Suda T, Oike Y, Araki E
    • Journal Title

      Biochem Biophys Res Coromun 379

      Pages: 806-811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis.2009

    • Author(s)
      Fujisawa K, Nishikawa T, Kukidome D, Imoto K, Yamashiro T, Motoshima H, Matsumura T, Araki E
    • Journal Title

      Biochem Biophys Res Commun 379

      Pages: 43-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] TZDs reduce mitoohondrial ROS production and enhance mitochondrial biogenesis.2009

    • Author(s)
      Fujisawa K, Nishikawa T, et a
    • Journal Title

      Biochem Biophys Res Commun 379

      Pages: 43-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Angptl 4 deficiency improves lipid metabolism, suppresses foamcell formation and protects against atherosclerosis.2009

    • Author(s)
      Adachi H, Nishikawa T, et al
    • Journal Title

      Biochem Biophys Res Commun 379

      Pages: 806-811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues2008

    • Author(s)
      Kojima K, Motoshima H, Tsutsumi A, Igata M, Matsumura T, Kondo T, Kawashima J, Ichinose K, Furukawa N, Inukai K, Katayama S, Goldstein BJ, Nishikawa T, Tsuruzoe K, Araki E
    • Journal Title

      Biochem Biophys Res Commun 376

      Pages: 434-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice2008

    • Author(s)
      Goto, H., Nishikawa, T.*, Sonoda, K., Kondo, T., Kukidome, D., Fujisawa, K., Yamashiro, T., Motoshima, H., Matsumura, T., Tsuruzoe, K., Araki, E.
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 814-820

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues2008

    • Author(s)
      Kojima K, Motoshima H, Tsutsumi A, Igata M, Matsumura T, Kondo T, Kawashima J, Ichinose K, Furukawa N, Inukai K, Katayama S, Goldstein BJ, Nishikawa T, Tsuruzoe K, Araki E.
    • Journal Title

      Biochem Biophys Res Commun 376

      Pages: 434-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591059
  • [Journal Article] Rottlerin activates AMPK possibly through LKBl in vascular eelIs and tissues.2008

    • Author(s)
      Kojima K, Nishikawa T, et al
    • Journal Title

      Biochem Biophys Res Commun 376

      Pages: 434-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice2008

    • Author(s)
      Goto H, Nishikawa T, Sonoda K, Kondo T, Kukidome D, Fujisawa K, Yamashiro T, Motoshima H, Matsumura T, Tsuruzoe K, Araki E
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 814-820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Rottlerin activates AMPK possibly through LKBl in vascular cells and tissues.2008

    • Author(s)
      Kojima K, Motoshima H, Tsutsumi A, Igata M, Matsumura T, Kondo T, Kawashima J, Ichinose K, Furukawa N, Inukai K, Katayama S, Goldstein BJ, Nishikawa T, Tsuruzoe K, Araki E
    • Journal Title

      Biochem Biophys Res Commun 376

      Pages: 434-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-a(PPARa) and PPARy through MAPK-dependent COX-2 expression in macrophages.2008

    • Author(s)
      Taketa, K., Matsumura, T., Yano, M., Ishii, N., Senokuchi, T., Motoshima, H., Murata, Y., Kim-Mitsuyama, S., Kawada, T., Itabe, H., Takeya, M., Nishikawa, T., Tsuruzoe, K., Araki, E.
    • Journal Title

      J Biol Chem 283

      Pages: 9852-9862

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Ox-LDL activates PPARα and PPARγ through MAPK-dependent COX-2 expression in macrophages2008

    • Author(s)
      Taketa K, Matsumura T, Yano M, Ishii N, Senokuchi T, Motoshima H, Murata Y, Kim-Mitsuyama S, Kawada T, Itabe H, Takeya M, Nishikawa T, Tsuruzoe K, Araki E
    • Journal Title

      J Biol Chem 283

      Pages: 9852-9862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Oxidized low density lipoprotein activatesperoxisome proliferator-activatedreceptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages2008

    • Author(s)
      Taketa K, Matsumura T, Yano M, Ishii N, Senokuchi T, Motoshima H, Murata Y, Kim-Mitsuyama S, Kawada T, Itabe H, Takeya M, Nishikawa T, Tsuruzoe K, Araki E.
    • Journal Title

      J Biol Chem 283

      Pages: 9852-98621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591059
  • [Journal Article]2007

    • Author(s)
      Nishikawa T
    • Journal Title

      Diabetes Res Clin Prat 77S

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Troglitazone inhibits oxidized low-density lipoprotein-induced macrophage proliferation : impact of the suppression of nuclear translocation of ERK1/22007

    • Author(s)
      Yano, M., Matsumura, T., Senokuchi, T., Ishii, N., Motoshima, H., Taguchi, T., Matsuo, T., Sonoda, K., Kukidome, D., Sakai, M., Kawada, T., Nishikawa, N., Araki, E.
    • Journal Title

      Atherosclerosis 191

      Pages: 22-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production on diabetic vascular complications2007

    • Author(s)
      Nishikawa T, Kukidome D, Sonoda K, Fujisawa K, Matsuhisa T, Motoshima H, Matsumura T, Araki E
    • Journal Title

      Diabetes Res Clin Pract 77Suppl1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Statins activate peroxisome proliferator-activated receptor gamma through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages.2007

    • Author(s)
      Yano, M., Matsumura, T., Senokuchi, T., Ishii, N., Murata, Y., Taketa, K., Motoshima, H., Taguchi, T., Sonoda, K., Kukidome, D., Takuwa, Y., Kawada, T., Brownlee, M., Nishikawa, T., Araki, E.
    • Journal Title

      Circ Res 100

      Pages: 1442-1451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production on diabetic vascular complications2007

    • Author(s)
      Nishikawa T, et. al.
    • Journal Title

      Diabetes Res Clin Prat 77S

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of insulin resistance2007

    • Author(s)
      Nishikawa T, et. al.
    • Journal Title

      Diabetes Res Clin Prat 77S

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Troglitazone Inhibits Oxidized Low-Density Lipoprotein-Induced Macrophage Proliferation : Impact of the Suppression of Nuclear Translocation of ERK 1/22007

    • Author(s)
      Yano M, Nishikawa T et al.
    • Journal Title

      Atherosclerosis 191

      Pages: 22-32

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of insulin resistance2007

    • Author(s)
      Nishikawa T, Kukidome D, Sonoda K, Fujisawa K, Matsuhisa T, Motoshima H, Matsumura T, Araki E
    • Journal Title

      Diabetes Res Clin Pract 77Suppl1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of diabetic mellitus and its complications2007

    • Author(s)
      Nishikawa T, et. al.
    • Journal Title

      Antioxid Redox Signal 9

      Pages: 343-353

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production on diabetic vascular complications.(* corresponding author)2007

    • Author(s)
      Nishikawa, T.*, Kukidome, D., Sonoda, K., Fujisawa, K., Matsuhisa, T., Motoshima, H., Matsumura, T., Araki, E.
    • Journal Title

      Diabetes Res Clin Prat 77S

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Troglitazone inhibits oxidized low-density lipoprotein-induced macrophage proliferation : impact of the suppression of nuclear translocation of ERK1/22007

    • Author(s)
      Yano M, Matsumura T, Senokuchi T, Ishii N, Motoshima H, Taguchi T, Matsuo T, Sonoda K, Kukidome D, Sakai M, Kawada T, Nishikawa N, Araki E
    • Journal Title

      Atherosclerosis 191

      Pages: 22-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of diabetic mellitus and its complications.2007

    • Author(s)
      Nishikawa T
    • Journal Title

      Antioxid Redox Signal 9

      Pages: 343-353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of diabetic mellitus and its complications.2007

    • Author(s)
      Nishikawa T, Araki E
    • Journal Title

      Antioxid.Redox Signal 9

      Pages: 343-353

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of insulin resistance.2007

    • Author(s)
      Nishikawa T
    • Journal Title

      Diabetes Res Clin Prat 77S

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of insulin resistance.(* corresponding author)2007

    • Author(s)
      Nishikawa, T.*, Kukidome, D., Sonoda, K., Fujisawa, K., Matsuhisa, T., Motoshima, H., Matsumura, T., Araki, E.
    • Journal Title

      Diabetes Res Clin Pract77S

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Statins activate peroxisome proliferator-activated receptor-γ through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages2007

    • Author(s)
      Yano M, Matsumura T, Senokuchi T, Ishii N, Murata Y, Taketa K, Motoshima H, Taguchi T, Sonoda K, Kukidome D, Takuwa Y, Kawada T, Brownlee M, Nishikawa T, Araki E
    • Journal Title

      Circ Res 100

      Pages: 1442-1451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Journal Article] Impact of mitochondrial ROS production in the pathogenesis of diabetic mellitus and its complications.(* corresponding author)2007

    • Author(s)
      Nishikawa, T.*, Araki, E.
    • Journal Title

      Antioxid Redox Signal 9

      Pages: 343-353

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production possibly through induction of MnSOD and promotion of mitochondrial biogenesis in HUVECs.2006

    • Author(s)
      Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Matsumura T, Araki E
    • Journal Title

      Diabetes 55

      Pages: 120-127

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Impact of mitochondrial reactive oxygen species (ROS) and apoptosis signal-regulating kinase 1 (ASK1) on insulin signaling.2006

    • Author(s)
      Imoto K, Kukidome D, Nishikawa T, Matsuhisa T, Sonoda K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Tsuruzoe K, Matsumura T, Ichijo H, Araki E
    • Journal Title

      Diabetes 55

      Pages: 1197-1204

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 糖尿病合併症におけるミトコンドリア由来活性酸素の意義2006

    • Author(s)
      西川武志
    • Journal Title

      糖尿病合併症学会誌 20

      Pages: 140-144

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production possibly through induction of MnSOD and promotion of mitochondrial biogenesis in HUVECs.2006

    • Author(s)
      Kukidome D, Nishikawa T et al.
    • Journal Title

      Diabetes 55

      Pages: 120-127

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Impact of mitochondrial reactive oxygen species (ROS) and apoptosis signal-regulating kinase 1 (ASK1) on insulin signaling.2006

    • Author(s)
      Imoto K, Kukidome D, Nishikawa T et al.
    • Journal Title

      Diabetes (In press)

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 糖尿病合併症の分子生物学-ミトコンドリア由来活性酸素の意義-2006

    • Author(s)
      西川武志
    • Journal Title

      日本体質医学会誌 68

      Pages: 119-123

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial reactive oxygen species (ROS) and apoptosis signal-regulating kinase 1 (ASK1) on insulin signaling.2006

    • Author(s)
      Imoto K, Kukidome D, Nishikawa T et al.
    • Journal Title

      Diabetes 55

      Pages: 1197-1204

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production possibly through induction of MnSOD and promotion of mitochondrial biogenesis in HUVECs.2006

    • Author(s)
      Kukidome D, Nishikawa T et al.
    • Journal Title

      Diabetes 55

      Pages: 120-127

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Impact of mitochondrial reactive oxygen species (ROS) and apoptosis signal-regulating kinase 1 (ASK1) on insulin signaling.2006

    • Author(s)
      Imoto K, Kukidome D, Nishikawa T et al.
    • Journal Title

      Diabetes 55

      Pages: 1197-1204

    • Data Source
      KAKENHI-PROJECT-18590995
  • [Journal Article] Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway.2005

    • Author(s)
      Senokuchi T, Matsumura T, Sakai M, Yano M, Taguchi T, Matsuo T, Sonoda K, Kukidome D, Imoto K, Nishikawa T, Kim-Mitsuyama S, Takuwa Y, Araki E
    • Journal Title

      J Biol Chem 280

      Pages: 6627-6633

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.2005

    • Author(s)
      Igata M, Motoshima H, Tsuruzoe K, Kojima K, Matsumura T, Kondo T, Taguchi T, Nakamaru K, Yano M, Kukidome D, Matsumoto K, Toyonaga T, Asano T, Nishikawa T, Araki E
    • Journal Title

      Circ Res 97

      Pages: 837-844

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Statins suppress oxidized low-density lipoprotein-induced macrophage proliferation by inactivation of small G protein-p38 MAPK pathway.2005

    • Author(s)
      Senokuchi T, Matsumura T, Nishikawa T, et al.
    • Journal Title

      J Biol Chem 280

      Pages: 6627-6633

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.2005

    • Author(s)
      Igata M, Motoshima H, Nishikawa T et al.
    • Journal Title

      Circ Res 97

      Pages: 837-844

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 糖尿病網膜症のリスクファクターとコントロール2005

    • Author(s)
      岸川秀樹, 荒木栄一, 榊田典治, 西川武志, 和氣仲庸
    • Journal Title

      日本臨床 63

      Pages: 237-243

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 酸化ストレスOxidative stress2005

    • Author(s)
      西川武志, 松村剛, 荒木栄一
    • Journal Title

      先端医療シリーズ32糖尿病の最新医療

      Pages: 161-166

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Statins suppress oxidized low-density lipoprotein-induced macrophage proliferation by inactivation of small G protein-p38 MAPK pathway.2005

    • Author(s)
      Senokuchi T, Matsumura T, Nishikawa T, et al.
    • Journal Title

      J Biol Chem (in press)

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 酸化ストレス2005

    • Author(s)
      荒木栄一, 西川武志
    • Journal Title

      日本臨床 63

      Pages: 73-78

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein.2004

    • Author(s)
      Senokuchi T, Matsumura T, Sakai M, Matsuo T, Yano M, Kiritoshi S, Sonoda K, Kukidome D, Nishikawa T, Araki E
    • Journal Title

      Atherosclerosis 176

      Pages: 233-245

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 糖尿病と8-OHdG2004

    • Author(s)
      西川武志等
    • Journal Title

      内分泌・糖尿病科 18

      Pages: 307-307

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein.2004

    • Author(s)
      Senokuchi T, Matsumura T, Nishikawa T, et al.
    • Journal Title

      Atherosclerosis 176

      Pages: 233-233

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 血糖コントロールによる網膜症抑制効果-熊本スタディの成績より-2004

    • Author(s)
      西川武志等
    • Journal Title

      糖尿病合併症 18

      Pages: 72-72

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via in activation of NF-kappaB.2004

    • Author(s)
      Matsuo T, Matsumura T, Sakai M, Senokuchi T, Yano M, Kiritoshi S, Sonoda K, Kukidome D, Pestell RG, Brownlee M, Nishikawa T, Araki E
    • Journal Title

      Biochem Biophys Res Commun 314

      Pages: 817-823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Extracellular signal-regulated kinase and p38 mitogen-activated protein kinas mediate macrophage proliferation induced by oxidized low-density lipoprotein.2004

    • Author(s)
      Senokuchi T, Matsumura T, Nishikawa T, et al.
    • Journal Title

      Atherosclerosis 176

      Pages: 233-233

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-KB.2004

    • Author(s)
      Matsuo T, Matsumura T, Nishikawa T, et al.
    • Journal Title

      Biochem Biophys Res Commum 314

      Pages: 817-817

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kB.2004

    • Author(s)
      Matsuo T, Matsumura T, Nishikawa T, et al.
    • Journal Title

      Biochem Biophys Res Commun 314

      Pages: 817-817

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] 経口ブドウ糖負荷試験による負荷後血糖値と脈派伝播速度および冠動脈疾患リスクとの相関2004

    • Author(s)
      東隆行, 西川武志, 荒木栄一
    • Journal Title

      糖尿病 47

      Pages: 807-807

    • Data Source
      KAKENHI-PROJECT-16590889
  • [Journal Article] Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes

    • Author(s)
      Matsumura T, Taketa K, Motoshima H, Senokuchi T, Ishii N, Kinoshita H, Fukuda K, Yamada S, Kukidome D, Kondo T, Hisada A, Katoh T, Shimoda S, Nishikawa T, Araki E
    • Journal Title

      Cardiovasc Diabetol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Journal Article] Oxidative stress ; a cause and a therapeutic target of diabetic complications

    • Author(s)
      Araki E, Nishikawa T
    • Journal Title

      Journal of Diabetes Investigation (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Journal Article] Mitochondrial reactive oxygen species in the pathogenesis of early diabetic nephropathy

    • Author(s)
      Nishikawa T, Brownlee M, Araki E
    • Journal Title

      J Diabetes Invest

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 低血糖によるミトコンドリア由来活性酸素(mtROS)と糖尿病網膜症初期変化の関連2016

    • Author(s)
      久木留大介、梶原伸宏、佐田公範、本島寛之、松村剛、西川武志、荒木栄一
    • Organizer
      第28回分子糖尿病学シンポジウム
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-15K09393
  • [Presentation] 糖尿病合併症の機序解明-低血糖による糖尿病合併症増悪におけるミトコンドリア由来活性酸素(mtROS)の関与2016

    • Author(s)
      梶原伸宏, 久木留大介, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-15K09393
  • [Presentation] 低血糖による糖尿病合併症増悪機序 -低血糖誘導ミトコンドリア由来活性酸素(mtROS)の関与-2016

    • Author(s)
      梶原伸宏, 久木留大介, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第54回日本糖尿病学会九州地方会
    • Place of Presentation
      鹿児島
    • Year and Date
      2016-10-14
    • Data Source
      KAKENHI-PROJECT-15K09393
  • [Presentation] 糖尿病合併症の機序解明―低血糖による糖尿病合併症増悪におけるミトコンドリア由来活性酸素(mtROS)の関与.2016

    • Author(s)
      梶原伸宏, 久木留大介, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] 急激な血糖是正による糖尿病網膜症増悪の機序解明-ミトコンドリアROS の関与-.2016

    • Author(s)
      久木留大介, 梶原伸宏, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第31回日本糖尿病合併症学会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] Hypoglycemia-induced retinal neurodegeneration is associated with mitochondrial ROS production caused by fatty acid oxidation2016

    • Author(s)
      N. Kajihara, D. Kukidome, K. Sada, H. Motoshima, T. Matsumura, T. Nishikawa, E. Araki
    • Organizer
      52th EASD Annual Meeting
    • Place of Presentation
      Messe Munchen, Munich, Germany
    • Year and Date
      2016-09-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09393
  • [Presentation] 急激な血糖是正による糖尿病網膜症増悪の機序解明-ミトコンドリアROSの関与-2016

    • Author(s)
      久木留大介, 梶原伸宏, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第31回日本糖尿病合併症学会
    • Place of Presentation
      宮城
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-15K09393
  • [Presentation] 低血糖による糖尿病合併症増悪機序 -低血糖誘導ミトコンドリア由来活性酸素( mtROS)の関与-.2016

    • Author(s)
      梶原伸宏, 久木留大介, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第54回日本糖尿病学会九州地方会
    • Place of Presentation
      かごしま県民交流センター
    • Year and Date
      2016-10-14
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] 合併症予防におけるヘモグロビンA1cの意義と限界2016

    • Author(s)
      西川武志
    • Organizer
      第31回日本糖尿病合併症学会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2016-10-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] 低血糖による糖尿病合併症発症増悪機序におけるミトコンドリア由来活性酸素(mtROS)の関与.2016

    • Author(s)
      梶原伸宏, 久木留大介, 佐田公範, 本島寛之, 松村剛, 西川武志, 荒木栄一
    • Organizer
      第66回日本体質医学会総会
    • Place of Presentation
      和歌山県JAビル
    • Year and Date
      2016-09-03
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] 高血糖は細胞内低酸素とミトコンドリア由来活性酸素種(mtROS)産生を誘導し、両者の相互作用が糖尿病合併症を進展する.2015

    • Author(s)
      佐田公紀, 西川武志, 久木留大介, 梶原伸宏, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      第27回分子糖尿病学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-12-05
    • Data Source
      KAKENHI-PROJECT-25461360
  • [Presentation] 合併症予防における血糖管理の意義と展望2015

    • Author(s)
      西川武志
    • Organizer
      第30回日本糖尿病合併症学会
    • Place of Presentation
      愛知県産業労働センター ウインクあいち
    • Year and Date
      2015-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] 糖尿病合併症と酸化ストレス2015

    • Author(s)
      西川武志
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関市民会館
    • Year and Date
      2015-05-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] インスリン抵抗性および動脈硬化症発症・進展におけるマクロファージ増殖の意義の検討.2015

    • Author(s)
      瀬ノ口隆文, 山田沙梨恵, 松村剛, 本島寛之, 石井規夫, 福田一起, 村上彩子, 守田雄太郎, 西川武志, 荒木栄一
    • Organizer
      第53回日本糖尿病学会九州地方会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25461360
  • [Presentation] 大血管合併症の発症・進展予防の戦略2015

    • Author(s)
      西川武志
    • Organizer
      第53回日本糖尿病学会九州地方会
    • Place of Presentation
      アクロス福岡
    • Year and Date
      2015-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] Cellular hypoxia and mitochondrial reactive oxygen species may promote hyperglycemic damage in a coordinated manner.2015

    • Author(s)
      Kiminori S, Nishikawa T, Kukidome D, Kajiwara N, Motoshima H, Matsumura T, Araki E
    • Organizer
      the 51st Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Stockholmsmässan, Stockholm
    • Year and Date
      2015-09-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461340
  • [Presentation] 高血糖によるミトコンドリア由来活性酸素種(mtROS)と組織内低酸素との関連性2013

    • Author(s)
      佐田公範, 西川武志, 久木留大介, 梶原伸宏, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      第51回日本糖尿病学会九州地方会
    • Place of Presentation
      沖縄コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 酸化ストレスからみた合併症治療の展望2013

    • Author(s)
      西川武志, 佐田公範, 久木留大介, 荒木栄一
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本県民交流館パレア
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 糖尿病合併症進展度と小径線維神経における痛覚閾値との関連性2013

    • Author(s)
      佐藤美希,久木留大介,泉香織,狩場宏美,古庄正嗣,守田雄太郎,河島淳司,下田誠也,西川武志,荒木栄一
    • Organizer
      第51回日本糖尿病学会九州地方会
    • Place of Presentation
      沖縄コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 高血糖によるミトコンドリア由来活性酸素種(mtROS)と組織内低酸素との関連性2013

    • Author(s)
      佐田公範,西川武志,久木留大介,梶原伸宏,本島寛之,松村剛,荒木栄一
    • Organizer
      第51回日本糖尿病学会九州地方会
    • Place of Presentation
      沖縄コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 小径線維神経における痛覚閾値と糖尿病合併症進展度との関連性2013

    • Author(s)
      久木留大介,佐藤美希,下田誠也,西川武志,荒木栄一
    • Organizer
      第28回日本糖尿病合併症学会
    • Place of Presentation
      旭川グランドホテル(ワークショップ)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 酸化ストレスからみた合併症治療の展望2013

    • Author(s)
      西川武志,佐田公範,久木留大介,荒木栄一
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      くまもと県民交流会館パレア(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 各甲状腺ホルモン測定試薬の反応性の相違からFT3偽高値を呈した1例2013

    • Author(s)
      久木留大介,河島淳司,井形元維,近藤龍也,西川武志,荒木栄一
    • Organizer
      第56回日本甲状腺学会学術集会
    • Place of Presentation
      和歌山県民文化会館
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] Pain threshold values of small fibers are associated with the severity of diabetic complications2013

    • Author(s)
      Kukidome D, Sato M, Shimoda S, Nishikawa T, Araki E
    • Organizer
      49th EASD Annual Meeting 2013
    • Place of Presentation
      Barceló Congresos, Spain
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] Lifestyle interventions reduce risk factors for metabolic syndrome and improve early insulin responses in subjects with an impaired early insulin response : The impact of early insulin response in Tabaruzaka Study2012

    • Author(s)
      Sada K, Nishikawa T, Yamashiro T, Kukidome D, Isami S, Motoshima H, Matsumura T, Araki E
    • Organizer
      The 72nd Annual Meeting of American Diabetes Association
    • Place of Presentation
      Pennsylvania Convention Center, USA
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] Lifestyle interventions reduce risk factors for metabolic syndrome and improve early insulin responses in subjects with an impaired early insulin response: The impact of early insulin response in Tabaruzaka Study2012

    • Author(s)
      Sada K, Nishikawa T, Yamashiro T, Kukidome D, Isami S, Motoshima H, Matsumura T, Araki E
    • Organizer
      American Diabetes Association 72nd Scientific Sessions
    • Place of Presentation
      Pennsylvania Convention Center, アメリカ
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 糖尿病合併症の体質と環境2012

    • Author(s)
      西川武志, 荒木栄一
    • Organizer
      第62回日本体質医学会総会
    • Place of Presentation
      大阪国際会議場
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 糖尿病合併症の体質と環境2012

    • Author(s)
      西川武志,荒木栄一
    • Organizer
      第62回日本体質医学会総会
    • Place of Presentation
      大阪国際会議場(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 糖尿病網膜症に対する集約的治療の重要性と合併症発症機序に基づく新規治療開発の可能性2011

    • Author(s)
      西川武志,久木留大介,荒木栄一
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌プリンスホテル(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 糖尿病性大血管障害と酸化ストレス2011

    • Author(s)
      西川武志, 久木留大介, 佐田公範, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      第49回糖尿病学会九州地方会(招待講演)
    • Place of Presentation
      福岡(アクロス福岡)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] 糖尿病性大血管障害と酸化ストレス2011

    • Author(s)
      西川武志,久木留大介,佐田公範,本島寛之,松村剛,荒木栄一
    • Organizer
      第49回糖尿病学会九州地方会
    • Place of Presentation
      アクロス福岡(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] インスリンからみた糖尿病の病態2011

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Organizer
      第45回糖尿病学の進歩
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病網膜症に対する集約的治療の重要性と合併症発症機序に基づく新規治療開発の可能性,2011

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Organizer
      第54回日本糖尿病学会年次学術集会(招待講演)
    • Place of Presentation
      札幌(札幌プリンスホテル)
    • Data Source
      KAKENHI-PROJECT-23591312
  • [Presentation] Mitochondrial reactive oxygen species : A cause and therapeutic target of diabetic complications.2010

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Organizer
      The 26th Kumamoto Medical Biosciences Symposium
    • Place of Presentation
      熊本大学医学部山崎記念会館,Kumamoto, Japan
    • Year and Date
      2010-06-19
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病神経障害2010

    • Author(s)
      西川武志
    • Organizer
      第48回日本糖尿病九州地方会
    • Place of Presentation
      別府ビーコンプラザ
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 熊本県における高齢者の腎機能障害の現状2010

    • Author(s)
      西川武志, 山城武司, 久木留大介, 吉永智昭, 本島寛之, 松村剛, 宮村信博, 荒木栄一
    • Organizer
      日本老年医学会 第20回九州地方会
    • Place of Presentation
      熊本大学医学部医学教育図書棟
    • Year and Date
      2010-03-13
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Mitochondrial reactive oxygen species : A cause and therapeutic target of diabetic complications.2010

    • Author(s)
      Nishikawa T, et al.
    • Organizer
      The 26th Kumamoto Medical Biosciences Symposium
    • Place of Presentation
      熊本大学医学部山崎記念会館
    • Year and Date
      2010-06-19
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Pathogenic role of mitochondrial reactive oxygen species in diabetes and its complications.2010

    • Author(s)
      西川武志, et al
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      京都国際会議場, 京都府
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] メタボリックシンドローム予備群への生活習慣改善指導によるメタボリックシンドローム発症抑制とその機序の解析(田原坂スタディ)2010

    • Author(s)
      西川武志, 山城武司, 荒木栄一
    • Organizer
      第13回日本病態栄養学会
    • Place of Presentation
      京都府国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 熊本県における高齢者の腎機能障害の現状2010

    • Author(s)
      西川武志, 等
    • Organizer
      日本老年医学会 第20回九州地方会
    • Place of Presentation
      熊本大学医学部医学教育図書棟, 熊本県
    • Year and Date
      2010-03-13
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病合併症発症のメカニズム2010

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Organizer
      第44回糖尿病学の進歩
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Pathogenic role of mitochondrial reactive oxygen species in diabetes and its complications.2010

    • Author(s)
      西川武志, 久木留大介, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      京都国際会議場,Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 酸化ストレスと糖尿病網膜症2010

    • Author(s)
      西川武志, 久木留大介, 荒木栄一
    • Organizer
      第25回日本糖尿病合併症学会
    • Place of Presentation
      びわ湖ホール・ピアザ淡海
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] メタボリックシンドローム予備群への生活習慣改善指導によるメタボリックシンドローム発症抑制とその機序の解析(田原坂スタディ)2010

    • Author(s)
      西川武志, 等
    • Organizer
      第13回日本病態栄養学会
    • Place of Presentation
      京都国際会議場, 京都府
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病合併症発症のメカニズム2010

    • Author(s)
      西川武志, 等
    • Organizer
      第44回糖尿病学の進歩
    • Place of Presentation
      大阪国際会議場, 大阪府
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Mitochondrial ROS and diabetic complications-Effect of mitochondrial ROS amelioration by activation of an AMPK-PGC-1α-pathway on the prevention of diabetic complications2009

    • Author(s)
      西川武志, et al
    • Organizer
      The 15th Korea-Japan Symposium on Diabetes Mellitus
    • Place of Presentation
      International Convention Center Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] ミトコンドリア異常と血管合併症2009

    • Author(s)
      西川武志, 等
    • Organizer
      第52回日本糖尿病学会総会
    • Place of Presentation
      大阪国際会議場, 大阪府
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病および糖尿病合併症の新規発症機構の解明-ミトコンドリア由来活性酸素の関与-2009

    • Author(s)
      西川武志
    • Organizer
      第46回日本糖尿病学会関東甲信越地方会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-01-24
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Impaired insulin secretion as well as insulin resistance influences the onset of metabolic syndrome and the progression of arteriosclerosis in Japanese with pre-metabolic syndrome.2009

    • Author(s)
      西川武志, 山城武司, 久木留大介, 藤澤和夫, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      The 69th Annual Meeting of American Diabetes Association
    • Place of Presentation
      Morial Convention Center, New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Mitochondrial ROS and diabetic complications-Effect of mitochondrial ROS amelioration by activation of an AMPK-PGC-1α-pathway on the prevention of diabetic complications.2009

    • Author(s)
      西川武志, 荒木栄一
    • Organizer
      The 15th Korea-Japan Symposium on Diabetes Mellitus
    • Place of Presentation
      International Convention Center, Jeju Island, Korea
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] ミトコンドリア異常と血管合併症2009

    • Author(s)
      西川武志, 久木留大介, 園田和洋, 切通伸介, 藤澤和洋, 山城武司, 後藤秀生, 荒木栄一
    • Organizer
      第52回日本糖尿病学会総会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] Impaired insulin secretion as well as insulin resistance influences the onset of metabolic syndrome and the progression of arteriosclerosis in Japanese with pre-metabolic syndrome2009

    • Author(s)
      西川武志, et al
    • Organizer
      The 69th Annual Meeting of American Diabetes Association
    • Place of Presentation
      Morial Convention Center, USA
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] メタボリックシンドローム(MS)予備群への生活習慣指導のMS発症抑制効果とその機序の解析(田原坂スタディ)2008

    • Author(s)
      西川武志, 山城武司, 本島寛之, 松村剛, 水流添覚, 荒木栄一
    • Organizer
      第58回日本体質学会総会
    • Place of Presentation
      メルパルク京都
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 酸化ストレスによるβ細胞障害2008

    • Author(s)
      西川武志
    • Organizer
      第46回日本糖尿病学会九州地方会
    • Place of Presentation
      久留米市石橋文化センター
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] メタボリッッシンドローム予備群における頸動脈病変と動脈硬化危険因子との関連2008

    • Author(s)
      西川武志など
    • Organizer
      第16回西日本肥満研究会
    • Place of Presentation
      宮崎
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] メタボリックシンドローム予備群における頸動脈病変と動脈硬化危険因子との関連2008

    • Author(s)
      西川武志, 山城武司, 藤澤和夫, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      第16回西日本肥満研究会
    • Place of Presentation
      フェニックス・シーガイア・リゾート
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病合併症発症機構解明への取り組み-ミトコンドリア由来活性酸素の役割2008

    • Author(s)
      西川 武志
    • Organizer
      第53回日本臨床検査医学会中国・四国支部総会
    • Place of Presentation
      岡山
    • Year and Date
      2008-02-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 糖尿病および糖尿病合併症の新規発症機構の解明-ミトコンドリア由来活性酸素の関与-2008

    • Author(s)
      西川武志
    • Organizer
      第51回日本糖尿病学会総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 血管内皮特異的MnSOD発現マウスでの検討-酸化ストレス・脂質異常症への効果2008

    • Author(s)
      西川武志など
    • Organizer
      第51回日本糖尿病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 糖尿病および糖尿病合併症の新規発症機構の解明-ミトコンドリア由来活性酸素の関与-2008

    • Author(s)
      西川武志
    • Organizer
      第51回日本糖尿病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] 酸化ストレスによるβ細胞障害2008

    • Author(s)
      西川武志
    • Organizer
      第46回日本糖尿病学会九州地方会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] メタボリックシンドローム(MS)予備群への生活習慣指導のMS発症抑制効果とその機序の解析(田原坂スタディ)2008

    • Author(s)
      西川武志など
    • Organizer
      第58回日本体質学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] ニフェジピンによるPPARγ活性化を介した抗動脈硬化作用機序の解明2008

    • Author(s)
      松村剛, 石井規夫, 木下博之, 中尾紗綾, 本島寛之, 西川武志, 荒木栄一
    • Organizer
      第31回日本高血圧学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Presentation] 血管内皮特異的MnSOD発現マウスでの検討-酸化ストレス・脂質異常症への効果2008

    • Author(s)
      西川武志, 後藤秀生, 園田和洋, 水流添覚, 近藤龍也, 藤澤和夫, 山城武司, 本島寛之, 松村剛, 荒木栄一
    • Organizer
      第51回日本糖尿病学会総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-20591065
  • [Presentation] スタチン製剤による抗動脈硬化作用の新規機序解明-PPARα, PPARγ活性誘導効果の関与2007

    • Author(s)
      松村剛, 矢野美由紀, 石井則夫, 村田雄介, 竹田佳代, 瀬ノ口隆文, 本島寛之, 西川武志, 荒木栄一
    • Organizer
      第50回日本糖尿病学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Presentation] Pathogenic role of mitochondrial ROS in diabetes and its complications2007

    • Author(s)
      Nishikawa T
    • Organizer
      14th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 体質医学からみた血管病代謝内分泌(基礎)の立場から-血管病発症におけるミトコンドリア由来活性酸素の役割2007

    • Author(s)
      西川 武志
    • Organizer
      第57回日本体質学会総会
    • Place of Presentation
      大分
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 田原坂スタディにおける介入指導効果の持続性の検討2007

    • Author(s)
      西川 武志
    • Organizer
      第45回日本糖尿病学会九州地方会
    • Place of Presentation
      宮崎
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] スタチンによるPPARα, PPARγを介した抗動脈硬化作用の解明2007

    • Author(s)
      松村剛, 矢野美由紀, 石井則夫, 竹田佳代, 村田雄介, 瀬ノ口隆文, 本島寛之, 西川武志, 荒木栄一
    • Organizer
      第39回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19591056
  • [Presentation] Pathogenic role of mitochondrial ROS in diabetes and its complications2007

    • Author(s)
      Nishikawa T
    • Organizer
      The 14th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] Pathogenic role of mitochondrial ROS in diabetes and its complications2007

    • Author(s)
      Nishikawa, T.
    • Organizer
      The 14th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 体質医学からみた血管病 代謝内分泌(基礎)の立場から-血管病発症におけるミトコンドリア由来活性酸素の役割2007

    • Author(s)
      西川 武志
    • Organizer
      第57回日本体質学会総会
    • Place of Presentation
      大分
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] Impact of mitochondrial ROS production in the pathogenesis of diabetic vascular complications.2006

    • Author(s)
      Nishikawa, T.
    • Organizer
      Severance Hospital Diabetes Center 10th Anniversary International Symposium on Diabetes Mellitus
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2006-05-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 合併症のメカニズム2006

    • Author(s)
      西川 武志
    • Organizer
      第44回日本糖尿病学会九州地方会
    • Place of Presentation
      熊本
    • Year and Date
      2006-10-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] Impact of mitochondrial ROS production in the pathogenesis of diabetic vascular complications2006

    • Author(s)
      Nishikawa T
    • Organizer
      Severance Hospital Diabetes Center 10th Anniversary International Symposium on Diabetes Mellitus
    • Place of Presentation
      Seoul
    • Year and Date
      2006-05-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 酸化ストレスと糖尿病合併症2006

    • Author(s)
      西川 武志
    • Organizer
      第41回糖尿病学の進歩
    • Place of Presentation
      札幌
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590995
  • [Presentation] 糖尿病と酸化ストレス

    • Author(s)
      西川武志
    • Organizer
      第52回日本糖尿病学会九州地方会
    • Place of Presentation
      熊本県民会館パレア
    • Year and Date
      2014-10-31 – 2014-11-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461340
  • 1.  ARAKI Eiichi (10253733)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 28 results
  • 2.  MATSUMURA Takeshi (20398192)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 28 results
  • 3.  MIYAMURA Nobuhiro (40274716)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 4.  MOTOSHIMA Hiroyuki (40398201)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 22 results
  • 5.  KONDO Tatsuya (70398204)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 6.  KUKIDOME Daisuke (10555759)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 38 results
  • 7.  SAKAKIDA Michiharu (50170577)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 8.  TOYONAGA Tetsushi (60295128)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TSURUZOE Kaku (50398202)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 10.  NISHIDA Kenro (50336244)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  大林 光念
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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