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FUKAZAWA Yohji  深澤 洋滋

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深澤 洋滋  フカザワ ヨウジ

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Researcher Number 70336882
Other IDs
Affiliation (Current) 2025: 関西医療大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 関西医療大学, 保健医療学部, 教授
2014 – 2021: 関西医療大学, 保健医療学部, 准教授
2012 – 2013: 関西医療大学, 保健医療学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 55050:Anesthesiology-related / Basic Section 47040:Pharmacology-related
Except Principal Investigator
Basic Section 52010:General internal medicine-related / Basic Section 59020:Sports sciences-related / Anesthesiology / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
かゆみ / 脊髄 / ガストリン放出ペプチド / 掻痒 / ミクログリア / グリア細胞 / 慢性掻痒 / AMPA受容体 / グルタミン酸 / ジフェニルシクロプロペノン … More / イミキモド / 後角 / DREDD / AMPA / 性差 / 接触性皮膚炎 / 乾癬 / DREADD … More
Except Principal Investigator
フェノタイプ / サイトカイン / 炎症 / ケモカイン / マクロファージ / 神経障害性疼痛 / 内分泌調節 / 微小炎症 / 腸内フローラ解析 / 骨代謝ホルモン / 腸内細菌叢 / 前十字靭帯 / 運動器 / 鍼刺激 / 骨代謝 / エストロゲン / 鍼灸 / 鍼 / 女性ホルモン / スポーツ傷害 / ニコチン / ミクログリア / ニコチン性アセチルコリン受容体 / STAT3 / 神経炎症 / α4β2 / ニコチン受容体 / 慢性炎症 / VEGF / MIP / CCL8 / CCL3 / エピジェネティクス / ヒストン / 慢性疼痛 Less
  • Research Projects

    (6 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (12 People)
  •  ミクログリアによるかゆみ神経調節機構の解明Principal Investigator

    • Principal Investigator
      深澤 洋滋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Kansai University of Health Sciences
  •  The Mechanisms of Bone Hormone Control with Accupuncture Stimulation via the Change of Gut Microbiota.

    • Principal Investigator
      Itoh Shunji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kansai University of Health Sciences
  •  Investigation on the role of the inflammatory factors in the neuro transduction of chronic pruritusPrincipal Investigator

    • Principal Investigator
      Fukazawa Yohji
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kansai University of Health Sciences
  •  Basic Research on the Risk of Sports Injury in Women: Optimization of Endogenous Hormones by Acupuncture Stimulation

    • Principal Investigator
      YAMAGUCHI Yumiko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kansai University of Health Sciences
  •  Novel therapeutics for macrophage-driven inflammatory diseases via nicotinic acetylcholine receptor signaling

    • Principal Investigator
      Kishioka Shiroh
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Wakayama Medical University
  •  Molecular mechanism of chronic pain via histone-dependent peripheral sensitization

    • Principal Investigator
      KIGUCHI Norikazu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Wakayama Medical University

All 2023 2021 2020 2019 2017 2015 2014 2012

All Journal Article Presentation

  • [Journal Article] Sexually dimorphic effects of pexidartinib on nerve injury-induced neuropathic pain in mice2023

    • Author(s)
      Saika Fumihiro、Fukazawa Yohji、Hatano Yu、Kishioka Shiroh、Hino Shinjiro、Suzuki Kentaro、Kiguchi Norikazu
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2023.10.10.561386

    • Open Access
    • Data Source
      KAKENHI-PROJECT-23K08371
  • [Journal Article] 霊長類における痒み調節機構2023

    • Author(s)
      木口倫一、深澤洋滋
    • Journal Title

      皮膚科

      Volume: 第4巻第3号 Pages: 301-308

    • Data Source
      KAKENHI-PROJECT-23K08371
  • [Journal Article] Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice Pharmacology Research and Perspective2021

    • Author(s)
      Norikazu Kiguchi, Yohji Fukazawa, Ayano Saika, Daisuke Uta, Fumihiro Saika, Tomoe Y. Nakamura, Mei-Chuan Ko, Shiroh Kishioka
    • Journal Title

      Pharmacology Research and Perspective

      Volume: - Issue: 3 Pages: 1-11

    • DOI

      10.1002/prp2.790

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06867, KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-19K09323, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
  • [Journal Article] Association between oxidative stress and microRNA expression pattern of ALS patients in the high-incidence area of the Kii Peninsula2020

    • Author(s)
      Yuya Arakawa, Shunji Itoh, Yohji Fukazawa, Hiroshi Ishiguchi, Junko Kohmoto, Masaya Hironishi, Hidefumi Ito, Tameko Kihira
    • Journal Title

      Brain Research

      Volume: 1746 Pages: 147035-147035

    • DOI

      10.1016/j.brainres.2020.147035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07813, KAKENHI-PROJECT-18H02743
  • [Journal Article] Critical role of GRP receptor?expressing neurons in the spinal transmission of imiquimod‐induced psoriatic itch2020

    • Author(s)
      Kiguchi Norikazu、Saika Fumihiro、Fukazawa Yohji、Matsuzaki Shinsuke、Kishioka Shiroh
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 40 Issue: 3 Pages: 287-290

    • DOI

      10.1002/npr2.12120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
  • [Journal Article] GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn2020

    • Author(s)
      Kiguchi Norikazu、Uta Daisuke、Ding Huiping、Uchida Hitoshi、Saika Fumihiro、Matsuzaki Shinsuke、Fukazawa Yohji、Abe Manabu、Sakimura Kenji、Ko Mei-Chuan、Kishioka Shiroh
    • Journal Title

      Neuropharmacology

      Volume: 170 Pages: 108025-108025

    • DOI

      10.1016/j.neuropharm.2020.108025

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19K09323, KAKENHI-PROJECT-20K07088
  • [Journal Article] Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation2017

    • Author(s)
      Kiguchi N, Sakaguchi H, Kadowaki Y, Saika F, Fukazawa Y, Matsuzaki S, Kishioka S
    • Journal Title

      J Pharmacol Sci

      Volume: 133 Issue: 1 Pages: 53-56

    • DOI

      10.1016/j.jphs.2016.11.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K10563, KAKENHI-PROJECT-16K08994
  • [Journal Article] Vascular endothelial growth factor signaling in injured nerves underlies peripheral sensitization in neuropathic pain.2014

    • Author(s)
      Kiguchi N, Kobayashi Y, Kadowaki Y, Fukazawa Y, Saika F, Kishioka S
    • Journal Title

      J Neurochem

      Volume: 129 Issue: 1 Pages: 169-178

    • DOI

      10.1111/jnc.12614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397
  • [Journal Article] CC-chemokine ligand 4/macrophage inflammatory protein-1β participates in the induction of neuropathic pain after peripheral nerve injury.2012

    • Author(s)
      Saika F, Kiguchi N, Kobayashi Y, Fukazawa Y, and Kishioka S
    • Journal Title

      Eur J Pain.

      Volume: 16 Issue: 9 Pages: 1271-1280

    • DOI

      10.1002/j.1532-2149.2012.00146.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356
  • [Journal Article] Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain2012

    • Author(s)
      Kiguchi N, et al
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 340 Issue: 3 Pages: 577-587

    • DOI

      10.1124/jpet.111.187724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791469, KAKENHI-PROJECT-22590090, KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356
  • [Journal Article] Activation of nicotinic acetylcholine receptors on bone marrow-derived cells relieves neuropathic pain accompanied by peripheral neuroinflamation.2012

    • Author(s)
      Kiguchi N, Kobayashi Y, Maeda T, Tominaga S, Nakamura J, Fukazawa Y, Ozaki M and Kishioka S
    • Journal Title

      Neurochem Int.

      Volume: 61 Issue: 7 Pages: 1212-1219

    • DOI

      10.1016/j.neuint.2012.09.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356
  • [Journal Article] Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms2012

    • Author(s)
      Iwai S, Kiguchi N, Kobayashi Y, Fukazawa Y, Saika F, Ueno K, Yamamoto C, Kishioka S
    • Journal Title

      Drug Discov Ther

      Volume: 6 Pages: 31-37

    • NAID

      130005054734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592356
  • [Presentation] マウスを用いた卵巣への鍼刺激の影響の検討2019

    • Author(s)
      伊藤俊治、河村菜捺美、山口由美子、深澤洋滋、櫻井威織、櫻井悠加、畑村育次
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K10911
  • [Presentation] 末梢免疫細胞を標的とした神経障害性疼痛病態の解明2015

    • Author(s)
      小林悠佳、木口倫一、深澤洋滋、雑賀史浩、前田武彦、岸岡史郎
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592356
  • 1.  KIGUCHI Norikazu (90433341)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 9 results
  • 2.  KISHIOKA Shiroh (60137255)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  YAMAGUCHI Yumiko (00454661)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  Itoh Shunji (50275351)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  畑村 育次 (80336883)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  KOBAYASHI Yuka (20511562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  雑賀 史浩 (10644099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  大瀧 博文 (00733172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SAKAGUCHI Haruka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KOBAYASHI Daichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KADOWAKI Yui
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  西谷 友重
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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