Hirate Yoshikazu 平手良和

… Alternative Names

HIRATE Yoshikazu 平手良和

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Researcher Number	70342839
Other IDs
Affiliation (Current)	2025: 北里大学, 一般教育部, 非常勤講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 東京医科歯科大学, 統合研究機構, 講師 2014 – 2016: 東京医科歯科大学, 実験動物センター, 講師 2015: 東京医科歯科大学, 実験動物センタ－, 講師 2015: 熊本大学, 発生医学研究所, 助教 2011 – 2013: 熊本大学, 発生医学研究所, 助教
Review Section/Research Field	Principal Investigator Developmental biology / Basic Section 42040:Laboratory animal science-related / Laboratory animal science Except Principal Investigator Animal production science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42040:Laboratory animal science-related / Developmental biology / Laboratory animal science
Keywords	Principal Investigator マウス / 着床 / Hippo経路 / Angiomotin / Amphiregulin / 着床シグナル / 分泌タンパク質 / 子宮 / RNA-seq / 着床不全 … More / プロテアーゼ / 胚盤胞 / 疾患モデル / 遺伝学 / 実験動物学 / CRISPR/Cas9 / 脱細胞化組織 / 幹細胞 / 子宮内膜上皮細胞 / 細胞置換 / 遺伝子導入 / in vivo エレクトロポレーション / 細胞移植 / ジフテリア毒素 / TRECK法 / 子宮内膜 / Lats / 非対称分裂 / 細胞極性 / 細胞間コミュニケーション / シグナル伝達 / 発生・分化 / 発生生物学 / 着床前胚 / 着床前 / カテニン / カドヘリン / 細胞接着 / Hippo 経路 / 細胞分化 … More Except Principal Investigator マウス / 哺乳動物 / 着床障害 / 着床不全 / Sox17 / 着床 / AMH / テストステロン / 顆粒膜細胞 / セルトリ細胞 / 性分化 / heterogenity / 性決定 / 卵精巣 / 性転換 / heterogeneity / 性的２型 / 支持細胞 / 肝臓 / 胆汁うっ滞 / 消失進化 / 胆汁鬱滞 / SOX17 / 胆道閉鎖症 / 進化 / 胆嚢 / 疾患モデル / 小児外科 / 獣医学 / 応用動物学 / 接着 / in vivo / 発生生物学 / 細胞生物学 / 胚発生 / 細胞極性 / 細胞間接着 / マウス初期胚 / 増殖制御 / 細胞競合 / Hippoシグナル / 細胞間コミュニケーション / 女性不妊 / 不妊 Less

SOX17, the master regulator gene in gallbladder wall, and biliary atresia
- Principal Investigator
  
  Yoshiakira Kanai
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
Elucidation of blastocyst-derived signals that induce uterine AREG expressionPrincipal Investigator
- Principal Investigator
  
  Hirate Yoshikazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokyo Medical and Dental University
In vivo analysis for the relation of embryonic implantation and maternal age
- Principal Investigator
  
  KANAI MASAMI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokyo Medical and Dental University
Cellular level analysis of an embryo implantation process by means of uterine epithelium replacementPrincipal Investigator
- Principal Investigator
  
  Hirate Yoshikazu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Medical and Dental University
Molecular characterization of mouse gonadal supporting cell lineages in a partial sex reversal
- Principal Investigator
  
  Kanai Yoshiakira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Animal production science
- Research Institution
  The University of Tokyo
Analysis of implantaion process by using Sox17 heterozygous mouse
- Principal Investigator
  
  KANAI Masami
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Medical and Dental University
Clarification of the reciprocal interactions between Amot and Lats in activation of the Hippo pathwayPrincipal Investigator
- Principal Investigator
  
  Hirate Yoshikazu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Tokyo Medical and Dental University
  Kumamoto University
Elucidation of cell position-dependent Hippo-pathway regulatorymechanisms in preimplantation embryosPrincipal Investigator
- Principal Investigator
  
  HIRATE Yoshikazu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Kumamoto University
Molecular basis of intercellular communication by Hippo pathway
- Principal Investigator
  
  SASAKI Hiroshi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Developmental biology
- Research Institution
  Osaka University
  Kumamoto University

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] MAB21L1 modulates gene expression and DNA metabolic processes in the lens placode2021
- Author(s)
  Yamada R, Oguri A, Fujiki K, Shirahige K, Hirate Y, Kanai-Azuma M, Takezoe H, Akimoto Y, Takahashi N, Kanai Y.
- Journal Title
  
  Dis Model Mech
  
  Volume: 14 Issue: 12
- DOI
  10.1242/dmm.049251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21384, KAKENHI-PROJECT-17H01501
[Journal Article] Early Crypt Formation Defects in the Uterine Epithelia of Sox17 Heterozygous Mice2021
- Author(s)
  Hirate Yoshikazu、Hayakawa Kana、Nakano Yuki、Kumazawa Shiori、Miura Kento、Kanai Yoshiakira、Kanai-Azuma Masami
- Journal Title
  
  Sexual Development
  
  Volume: N/A Issue: 1-6 Pages: 1-11
- DOI
  10.1159/000513386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06459, KAKENHI-PROJECT-17H01501
[Journal Article] Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules2021
- Author(s)
  Imura-Kishi Kasane、Uchida Aya、Tsunekawa Naoki、Suzuki Hitomi、Takase Hinako M.、Hirate Yoshikazu、Kanai-Azuma Masami、Hiramatsu Ryuji、Kurohmaru Masamichi、Kanai Yoshiakira
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1110-1110
- DOI
  10.1038/s41598-020-79987-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06397, KAKENHI-PROJECT-19J22868, KAKENHI-PROJECT-18K05953, KAKENHI-PUBLICLY-19H05249, KAKENHI-PROJECT-17H01501
[Journal Article] Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice.Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice.2019
- Author(s)
  Miura K, Harikae K, Nakaguchi M, Imaimatsu K, Hiramatsu R, Tomita A, Hirate Y, Kanai-Azuma M, Kurohmaru M, Ogura A, Kanai Y.
- Journal Title
  
  PLos One
  
  Volume: 14(3) Issue: 3 Pages: e0212367-e0212367
- DOI
  10.1371/journal.pone.0212367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15214, KAKENHI-PROJECT-19K16017, KAKENHI-PROJECT-17H01501
[Journal Article] Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.2018
- Author(s)
  Igarashi H, Uemura, M, Hiramatsu R, Hiramatsu R, Segami S, Pattarapanawan M, Hirate Y, Yoshimura Y, Hashimoto H, Higashiyama H, Sumitomo H, Kurohmaru M, Saijoh Y, Suemizu H, Kanai-Azuma M, Kanai Y.
- Journal Title
  
  Biol Reprod
  
  Volume: - Issue: 3 Pages: 578-589
- DOI
  10.1093/biolre/ioy079
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-18K06044, KAKENHI-PROJECT-18H02361, KAKENHI-PROJECT-17J11177, KAKENHI-PROJECT-17H01501, KAKENHI-PROJECT-16J40235
[Journal Article] Sox17 is Essential for Proper Formation of the Marginal Zone of Extraembryonic Endoderm Adjacent to a Developing Mouse Placental Disk.2018
- Author(s)
  Igarashi Hitomi, Uemura Mami, Hiramatsu Ryuji, Hiramatsu Ryuto, Segami Saki, Pattarapanawan Montri, Hirate Yoshikazu Yoshimura Yuki, Hashimoto Haruo, Higashiyama Hiroki, Sumitomo Hiroyuki, Kurohmaru Masamichi, Saijoh Yukio, Suemizu Hiroshi, Kanai-Azuma Masami, Kanai Yoshiakira.
- Journal Title
  
  Biology of Reproduction
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04282
[Journal Article] Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient model of biliary atresia.2017
- Author(s)
  Higashiyama H, Ozawa A, Sumitomo H, Uemura M, Fujino K, Igarashi H, Imaimatsu K, Tsunekawa N, Hirate Y, Kurohmaru M, Saijoh Y, Kanai-Azuma M, Kanai Y.
- Journal Title
  
  Development
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04282
[Journal Article] Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.2017
- Author(s)
  Higashiyama H, Ozawa A, Sumitomo H, Uemura M, Fujino K, Igarashi H, Imaimatsu K, Tsunekawa N, Hirate Y, Kurohmaru M, Saijoh Y, Kanai-Azuma M, Kanai Y.
- Journal Title
  
  Development
  
  Volume: 144 Issue: 10 Pages: 1906-1917
- DOI
  10.1242/dev.147512
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-16J40235, KAKENHI-PROJECT-15H04282
[Journal Article] Mouse Sox17 haploinsufficiency leads to female subfertility due to impared implantation.2016
- Author(s)
  Hirate Y, Suzuki H, Kawasumi M, Takase HM, Igarashi H, Naquet P, Kanai Y, Kanai-Azuma M.
- Journal Title
  
  Sci Rep
  
  Volume: - Issue: 1 Pages: 24171-24171
- DOI
  10.1038/srep24171
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04282, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-24228005
[Journal Article] Par-aPKC-dependent and -independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16-cell stage mouse embryos2015
- Author(s)
  Hirate, Y., Hirahara, S., Inoue, K., Kiyonari, H., Niwa, H., and Sasaki, H.
- Journal Title
  
  Development, Growth and Differentiation
  
  Volume: 57 Issue: 8 Pages: 544-556
- DOI
  10.1111/dgd.12235
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440112, KAKENHI-PUBLICLY-15H01495, KAKENHI-PUBLICLY-26112715
[Journal Article] The role of angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development2014
- Author(s)
  Hirate Y. and Sasaki H.
- Journal Title
  
  Tissue Barriers
  
  Volume: 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440112
[Journal Article] Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos.2013
- Author(s)
  Hirate Y, Hirahara S, Inoue K-i, Suzuki A, Alarcon VB, Akimoto K, Hirai T, Hara T, Adachi M, Chida K, Ohno S, Marikawa Y, Nakao K, Shimono A, Sasaki H
- Journal Title
  
  Curr. Biol.
  
  Volume: 23 Issue: 13 Pages: 1181-1194
- DOI
  10.1016/j.cub.2013.05.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21116003, KAKENHI-PLANNED-21116004, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23247036, KAKENHI-PROJECT-25440112, KAKENHI-PROJECT-25460362
[Journal Article] olarity-dependent distribution ofangiomotin localizes Hippo signaling inpreimplantation embryos.2013
- Author(s)
  Hirate, Y.
- Journal Title
  
  Curr. Biol.
  
  Volume: Vol.23(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770265
[Journal Article] Tead4 is constitutively nuclear, while nuclear vs. cytoplasmic Yap distribution is regulated in preimplantation embryos.2012
- Author(s)
  Hirate, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 109 Issue: 50
- DOI
  10.1073/pnas.1211810109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247036, KAKENHI-PROJECT-23770265, KAKENHI-PLANNED-21116003
[Journal Article] マウス初期胚発生におけるHippo pathwayの役割2011
- Author(s)
  佐々木洋、平手良和
- Journal Title
  
  細胞工学
  
  Volume: 30 Pages: 935-340
- Data Source
  KAKENHI-PROJECT-23770265
[Journal Article] マウス初期胚発生における Hippo pathway の役割2011
- Author(s)
  佐々木洋、平手良和
- Journal Title
  
  細胞工学
  
  Volume: Vol. 30 Pages: 935-940
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] 頭部外胚葉におけるレンズ誘導におけるMab21l1の機能2021
- Author(s)
  山田竜一、小栗晶、藤木克則、白髭克彦、平手良和、金井正美、竹添裕高、秋元義弘、高橋直樹、金井克晃.
- Organizer
  第44回日本分子生物学会年会. 2021年12月１-3日 (ハイブリッド開催, パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-17H01501
[Presentation] 着床開始を制御する胚由来セリンプロテアーゼの特定2021
- Author(s)
  田中柚希、平手良和、藤岡慶史、今井松健也、遠藤墾、畠中秀樹、金井　克晃、金井正美
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06459
[Presentation] SOX17による着床初期の陰窩形成とSOX9およびAmphiregulinの発現制御2021
- Author(s)
  平手　良和，早川　佳那，中野　有紀，熊澤　栞，三浦　健人，金井　克晃，金井　正美
- Organizer
  第68回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K06459
[Presentation] TRECK法による選択的細胞死と細胞移植による子宮内膜上皮置換の試み2019
- Author(s)
  平手良和，中野有紀，吉田達見，Dania Badran，伊藤日加瑠，上村麻実，金井克晃，金井正美
- Organizer
  第32回モロシヌス研究会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] TRECK法による細胞死の誘導と細胞移植による子宮内膜上皮置換法の確立2019
- Author(s)
  平手良和，中野有紀，吉田達見，伊藤日加瑠，上村麻実，金井克晃，金井正美
- Organizer
  第66回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] TRECK法を用いた子宮内膜上皮置換法の確立2018
- Author(s)
  中野有紀, 平手良和, 上村麻実, 金井克晃, 金井正美
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] 子宮SOX17の着床受容期における下流候補遺伝子の探索2018
- Author(s)
  平手良和、早川佳那、中野友紀、上村麻実、三浦健人、金井克晃、金井正美
- Organizer
  第65日本実験動物学会
- Data Source
  KAKENHI-PROJECT-18H02361
[Presentation] 子宮内膜上皮SOX17の胚盤胞接着および脱落膜形成への関与2018
- Author(s)
  平手良和、早川佳那、中野有紀、上村麻実、三浦健人、金井克晃、金井正美
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18H02361
[Presentation] Molecular pathways downstream of Sox17 in uterine epithelia during mouse implantation processes,2018
- Author(s)
  Hirate Yoshikazu, Kanai Yoshiakira, Kanai-Azuma Masami
- Organizer
  Eighth International Symposium on Vertebrate Sex Determination
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02361
[Presentation] 子宮SOX17の着床受容期における下流候補遺伝子の探索2018
- Author(s)
  平手良和, 早川佳那, 中野有紀, 上村麻実, 三浦健人, 金井克晃, 金井正美
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] 子宮内膜上皮SOX17の胚盤胞接着および脱落膜形成への関与2018
- Author(s)
  平手良和, 早川佳那, 中野有紀, 上村麻実, 三浦健人, 金井克晃, 金井正美
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] Amh欠損雄マウスを用いたミューラー管遺残症における遺残子宮の比較病態解析ワークショップ「脊椎動物の性決定、性分化の分子機構」2018
- Author(s)
  平松竜司、村田千晴、三浦健人、平手良和、金井正美、金井克晃
- Organizer
  第41回日本分子生物学会年会　パシフィコ横浜　2018年11月29日
- Data Source
  KAKENHI-PROJECT-17H01501
[Presentation] Sox17 heterozygous mutant females are defective in implantation2017
- Author(s)
  Hirate Yoshikazu, Hayakawa Kana, Toyomura Yuga, Igarashi Hitomi, Miura Kento, Kanai Yoshiakira, Kanai-Azuma Masami
- Organizer
  Annual Meeting of the Japanese Society of Developmental Biologists 50th
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] Sox17ヘテロ変異着床不全マウスにおける子宮上皮遺伝子の発現変化2017
- Author(s)
  平手良和, 早川佳那, 豊村友賀, 五十嵐瞳, 三浦健人, 金井克晃，金井正美
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] マウス子宮上皮における転写因子Sox17の発現は着床の成立に必須である2017
- Author(s)
  平手良和, 早川佳那, 中野有紀, 上村麻実, 三浦健人, 金井克晃, 金井正美
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] Sox17ヘテロ変異雌マウスの子宮における着床不全のメカニズム解析2017
- Author(s)
  早川佳那、平手良和、上村麻実、三浦健人、金井克晃、金井正美
- Organizer
  第160回日本獣医学会
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] Sox17ヘテロ変異雌マウスの子宮における着床不全のメカニズム解析2017
- Author(s)
  早川佳那, 平手良和, 上村麻実, 三浦健人, 金井克晃, 金井正美
- Organizer
  第160回日本獣医学会
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] マウス子宮上皮における転写因子Sox17の発言は着床の成立に必須である2017
- Author(s)
  平手良和、早川佳那、中野有紀、上村麻実、三浦健人、金井克晃、金井正美
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] Sox17ヘテロ変異着床不全マウスにおける子宮上皮遺伝子の発現変化2017
- Author(s)
  平手良和、早川佳那、豊村友賀、五十嵐瞳、三浦健人、金井克晃、金井正美
- Organizer
  第64回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] Sox17 heterozygous mutant females are defective in implantation2017
- Author(s)
  Yoshikazu Hirate, Kana Hayakawa, Yuga Toyomura, Hitomi Igarashi, Kento Miura, Yoshiakira Kanai, and Masami Kanai-Azuma
- Organizer
  The 50th Annual Meeting of the Japanese Society of Developmental Biologists cosponsored by APDBN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07133
[Presentation] Sox17ヘテロ雌マウスは着床受容能の低下のために低妊性となる2016
- Author(s)
  平手良和、鈴木仁美、川澄みゆり、高瀬比菜子、五十嵐瞳、金井克晃、金井正美
- Organizer
  第63回日本実験動物学会
- Place of Presentation
  ミューザ川崎（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] 着床不全モデルとしてのSox17変異マウスの解析2016
- Author(s)
  平手良和、金井正美
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] A possible involvement of a dose-dependent Sox17 activity of uterine epithelia in mouse implantation processes2015
- Author(s)
  Kanai-Azuma Masami, Yoshikazu Hirate, Miyuri Kawasumi, Hitomi Suzuki, Yoshiakira Kana
- Organizer
  7th International Symposium Biology of Vertebrate Sex Determination
- Place of Presentation
  Kona Hawaii (USA)
- Year and Date
  2015-04-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] マウス着床前胚の細胞分化制御におけるHippo経路と細胞極性の役割2015
- Author(s)
  平手　良和
- Organizer
  第１０８回日本繁殖生物学会大会
- Place of Presentation
  宮崎市民プラザ（宮崎県・宮崎市）
- Year and Date
  2015-09-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440112
[Presentation] Soxヘテロ雌マウスの着床におけるハプロ不全2015
- Author(s)
  平手良和、鈴木仁美、川澄みゆり、金井克晃、金井正美
- Organizer
  第62回日本実験動物学会
- Place of Presentation
  京都テレサ (京都府、京都市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] Sox17ヘテロ雌マウスは着床不全のために妊性の低下がおこる2015
- Author(s)
  平手良和、鈴木仁美、川澄みゆり、高瀬比菜子、五十嵐瞳、金井克晃、金井正美
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (兵庫県　神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04282
[Presentation] Phosphorylation of Angiomotin regulates the Hippo pathway in cell fate regulation of preimplantation mouse embryos2014
- Author(s)
  平手良和、平原志乃、井上健一、鈴木厚、Vernadeth B. Alarcon、秋本和憲、平井孝明、千田和広、大野茂男、Yusuke Marikawa、中尾和貴、下野明彦、佐々木洋
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25440112
[Presentation] Cell polarity suppresses Hippo signaling Cell polarity suppresses Hippo signaling2013
- Author(s)
  Hirate, Y.
- Organizer
  The 46th Annual Meeting of the JapaneseSociety of Developmental Biologists
- Place of Presentation
  くにびきメッセ(島根県松江市)
- Year and Date
  2013-05-30
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] Cell polarity suppresses Hippo signaling through the regulation of Angiomotin distribution in preimplantation mouse embryos2013
- Author(s)
  Yoshikazu Hirate
- Organizer
  第46回日本発生生物学会
- Place of Presentation
  くにびきメッセ（島根県松江市）
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] Position-dependent cell fatespecification by cell polarity-controlledAngiomotin distribution.2011
- Author(s)
  Hirate. Y.
- Organizer
  Mouse Molecular Genetics 2011
- Place of Presentation
  Hinxton, Cambridge, UK.
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] Cell polarity establishes positional difference in Hippo signaling by altering Angiomotin subcellular distribution in preimplantation mouse embryos2011
- Author(s)
  Hirate Y
- Organizer
  第44回日本発生生物学会年会
- Place of Presentation
  沖縄コンベンションセンター沖縄
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23247036
[Presentation] 細胞極性によるAngiomotinの細胞内分布制御がマウス着床前胚の位置依存的なHippo経路活性を確立する2011
- Author(s)
  平手良和
- Organizer
  日本発生生物学会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県)
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] Position-dependent cell fate specification by cell polarity-controlled Angiomotin distribution2011
- Author(s)
  Hirate Y
- Organizer
  Mouse Molecular Genetics 2011
- Place of Presentation
  Cambridge, UK
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23247036
[Presentation] Position-dependent cell fate specification by cell polarity-controlled Angiomotin distribution2011
- Author(s)
  Hirate Y
- Organizer
  KEY Forum in Developmental Biology and Regenerative Medicine
- Place of Presentation
  Kumamoto.Univ.、熊本
- Data Source
  KAKENHI-PROJECT-23247036
[Presentation] Position-dependent cell fate specification by cell polarity-controlled Angiomotin distribution2011
- Author(s)
  Yoshikazu Hirate
- Organizer
  Mouse Molecular Genetics 2011
- Place of Presentation
  ウェルカムトラストコンファレンスセンター(英国)
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] Cell polarity establishes positionaldifference in Hippo signaling by alteringAngiomotin subcellular distribution inpreimplantation mouse embryos (細胞極性による Angiomotin の細胞内分布制御がマウス着床前胚の位置依存的な Hippo 経路活性を確立する).2011
- Author(s)
  Hirate, Y.
- Organizer
  The 44th Annual Meeting of the JapaneseSociety of Developmental Biologists
- Place of Presentation
  沖縄コンベンションセンター(沖縄)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] Position-dependent cell fatespecification by cell polarity-controlledAngiomotin distribution.2011
- Author(s)
  Hirate, Y.
- Organizer
  KEY Forum in Developmental Biology andRegenerative Medicine
- Place of Presentation
  熊本大学(熊本).
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23770265
[Presentation] マウス着床前胚の細胞分化はAngiomotinリン酸化によるHippo経路の活性化によって制御されている
- Author(s)
  平手良和、平原志乃、井上健一、鈴木厚、Vernadeth B. Alarcon、秋本和憲、平井孝明、千田和広、大野茂男、Yusuke Marikawa、中尾和貴、下野明彦、佐々木洋
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25440112

1. Yoshiakira Kanai (30260326)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. SASAKI HIROSHI (10211939)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. KANAI Masami (70321883)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
4. 平松竜司 (70555284)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. WADA Ken-ichi (20525919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MAMADA Hiroshi (90568734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SATO Takashi (70555755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAMURA Keiichiro (30604483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松本悠貴 (40831384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 藤代準 (60528438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 九郎丸正道 (00148636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 高瀬比菜子 (40754528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TSUNEKAWA NAOKI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 藤木克則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirate Yoshikazu 平手 良和

HIRATE Yoshikazu 平手 良和

Research Projects

Research Products

Co-Researchers

SOX17, the master regulator gene in gallbladder wall, and biliary atresia

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Elucidation of blastocyst-derived signals that induce uterine AREG expressionPrincipal Investigator

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In vivo analysis for the relation of embryonic implantation and maternal age

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Cellular level analysis of an embryo implantation process by means of uterine epithelium replacementPrincipal Investigator

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Molecular characterization of mouse gonadal supporting cell lineages in a partial sex reversal

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Analysis of implantaion process by using Sox17 heterozygous mouse

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Clarification of the reciprocal interactions between Amot and Lats in activation of the Hippo pathwayPrincipal Investigator

Principal Investigator

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Elucidation of cell position-dependent Hippo-pathway regulatorymechanisms in preimplantation embryosPrincipal Investigator

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Molecular basis of intercellular communication by Hippo pathway

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[Journal Article] MAB21L1 modulates gene expression and DNA metabolic processes in the lens placode2021

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[Journal Article] Early Crypt Formation Defects in the Uterine Epithelia of Sox17 Heterozygous Mice2021

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[Journal Article] Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules2021

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[Journal Article] Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice.Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice.2019

Author(s)

Journal Title

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Data Source

[Journal Article] Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.2018

Hirate Yoshikazu 平手良和

HIRATE Yoshikazu 平手良和