OBATA Makoto 小幡誠

… Alternative Names

小幡誠オバタマコト

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Researcher Number	70343267
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help	2023: 山梨大学, 大学院総合研究部, 教授 2020: 山梨大学, 大学院総合研究部, 教授 2017 – 2019: 山梨大学, 大学院総合研究部, 准教授 2014 – 2016: 山梨大学, 総合研究部, 准教授 2013: 山梨大学, 医学工学総合研究部, 准教授 … More 2010 – 2011: 山梨大学, 大学院・医学工学総合研究部, 准教授 2009: 山梨大学, 医学工学総合研究部, 助教 2009: University of Yamanashi, 大学院・医学工学総合研究部, 助教 2007 – 2008: Nara Women's University, 大学院・人間文化研究科, 助教 2006: 奈良女子大学, 人間文化研究科, 助手 2005 – 2006: 奈良女子大学, 大学院・人間文化研究科, 助手 2005 – 2006: 奈良女子大学, 大学院人間文化研究科, 助手 2004: 奈良女子大学, 人間文化研究科, 助手 2002 – 2003: 奈良女子大学, 大学院・人間文化研究科, 助手 Less
Review Section/Research Field	Principal Investigator Polymer chemistry / Basic Section 35020:Polymer materials-related / Chemistry related to living body / 光生命科学 / 高分子合成 / Science and Engineering Except Principal Investigator Science and Engineering / Inorganic chemistry / Basic Section 37010:Bio-related chemistry / Bio-related chemistry
Keywords	Principal Investigator 高分子ミセル / ドラッグデリバリーシステム / 精密重合 / 糖質高分子 / 凝集誘起発光 / カルボラン / ホウ素中性子捕捉療法 / 核酸キャリア / RAFT重合 / ラジカル重合 … More / 一重項酸素 / 1,3-双極子付加環化反応 / 活性酸素 / ペプチド / 光増感剤 / 光線力学療法 / 光医療 / 光生命科学 / 糖 / O-グリコシル錯体 / ポリマー / レニウム / 配糖錯体 / ポルフィリン / 水素結合 / ポルフェニレンエチニレン / ポルフェリン … More Except Principal Investigator ポルフィリン / 光増感剤 / PDT / 光機能 / ポルフィリン誘導体 / PET / セラノスティクス / 糖鎖 / 医療 / 糖 / 金属錯体 / エネルギー移動 / 感圧塗料 / 電子移動 / 金属クラスター / BNCT / セラノスティクスがん医療 / がん治療効果 / がん集積性 / 水溶性 / 色素内包高分子ミセル / 高分子ポリマー / 機能性色素 / がんセラノスティクス / がん治療 / がん診断 / 色素 / 高分子ミセル / Theragnosis / がん診断(PET) / がん治療(PDT) / 腫瘍集積時間促進置換基 / 腫瘍集積性置換基 / 光細胞毒性試験 / がん診断（PDD） / がん治療（PDT） / Theranostics / メルカプトエタノール鎖 / グルコース鎖 / がん治療法(PDT) / がん診断法(PET) / ポルフィリン亜鉛錯体 / photosensitizer / thioglycoside / sugar / antitumor activity / growth inhibition / antifungal activity / medicine / インスリン / 糖尿病 / フラーレン / がん / 核画像診断 / 銀(I)錯体 / 真菌 / チオグリコシド / 抗癌活性 / 増殖阻害 / 抗菌活性 / クリックケミストリー / Re錯体 / 配糖錯体 / パラジウム錯体 / 白金錯体 / 薬理活性 / シッフ塩基 / ハイブリッド体 / バイオメカニズム / 制がん剤 / 光線力学療法 / ナフタレン / ルテニウム / ナノ制御 / 配位空間 / ITO電極 / 長鎖アルキル / SAM / 酸素感受性 / PSP / 光機能界面 / 陽極酸化アルミ皮膜 / ナフチル / 酸素センサ / 電荷分離 / ヘムエリトリン Less

Study on polymer-drug interaction by AIE technique for polymer micelle designPrincipal Investigator
- Principal Investigator
  
  小幡誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 35020:Polymer materials-related
- Research Institution
  University of Yamanashi
Development of PET-BNCT dual-functional porphyrin for theranostics drugs
- Principal Investigator
  
  Shiho Hirohara
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Ube National College of Technology
Development of Boron Carrier for BNCT by Precision Polymerization TechniquePrincipal Investigator
- Principal Investigator
  
  OBATA Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Polymer chemistry
- Research Institution
  University of Yamanashi
Development of water-soluble Zinc porphyrin aimed at Theranostics
- Principal Investigator
  
  HIROHARA SHIHO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Ube National College of Technology
Precision Synthesis of Block Glycopolymers for DDS Carrier targeting MacrophagesPrincipal Investigator
- Principal Investigator
  
  OBATA Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Polymer chemistry
- Research Institution
  University of Yamanashi
Synthesis of Cationic Glycopolymer and Development of Sugar-Coated Polyplex for Gene Delivery ApplicationPrincipal Investigator
- Principal Investigator
  
  OBATA Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  University of Yamanashi
Development of Glycoconjugated Hybrid Metal Complexes for the Next-Generation Advanced Medical Care
- Principal Investigator
  
  YANO Shigenobu
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Inorganic chemistry
- Research Institution
  Kyoto University
  Nara Women's University
Development of Novel Photosensitizers having Biofunctional Moieties for QOL-oriented Photodynamic TherapyPrincipal Investigator
- Principal Investigator
  
  OBATA Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  光生命科学
- Research Institution
  Nara Women's University
分子性有機・無機複合型光機能性素子の開発と光機能界面への応用
- Principal Investigator
  
  矢野重信
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Nara Women's University
配位空間のナノ制御による光応答性金属クラスターの構築と新機能開発
- Principal Investigator
  
  矢野重信
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Nara Women's University
Development of Glycoconjugated Hybrid Metal Complexes toward Frontier Medicinal Treatment and Elucidation of their Biomechanism
- Principal Investigator
  
  YANO Shigenobu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Inorganic chemistry
- Research Institution
  Nara Women's University
高度集積化複合色素を機能素子とする新規光機能性材料の技術開発
- Principal Investigator
  
  YANO Shigenobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Nara Women's University
立体規則性高分子をテンプレートとする光応答性ポルフィリン集積体の構築Principal Investigator
- Principal Investigator
  
  小幡誠
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Nara Women's University
配糖錯体を生体類似機能素子とする新規機能性ポリマーの開発Principal Investigator
- Principal Investigator
  
  小幡誠
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  高分子合成
- Research Institution
  Nara Women's University

[Book] Spectroscopic Tools for the Diagnosis and Treatment of Cancer2017
- Author(s)
  N.Miyoshi, K.Hirakawa, H. Horiuchi, S.Okazaki, S-I. Ogura, M.Obata, S.Hirohara
- Total Pages
  164
- Publisher
  三恵社
- Data Source
  KAKENHI-PROJECT-26410189
[Book] Photosynthesis. Energy from the sun(J. F. Allen, E. Gantt, J. H. Golbeck, and B. Osmond, Eds., Syntheses and Photochemical Properties of Trimanganese Compexes Containing Naphtyl Moieties)2008
- Author(s)
  S. Yano, M. Nakai, H. Ohi, T. Funabiki, R. Tanaka, I. Kinoshita, M. Obata
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19350031
[Book] J.F.Allen, E.Gantt, J.H.Golbeck, and B.Osmond, Eds., Springer. (Syntheses and Photochemical Properties of Trimanganese Compexes Containing Naphtyl Moieties)2008
- Author(s)
  S.Yano, M.Nakai, H.Ohi, T.Funabiki, R.Tanaka, I.Kinoshita, M.Obata
- Publisher
  Photosynthesis. Energy from the sun
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Effect of the hydrophobic segment of an amphiphilic block copolymer on micelle formation, zinc phthalocyanine loading, and photodynamic activity2021
- Author(s)
  M. Obata, S. Masuda, M. Takahashi, K. Yazaki, S. Hirohara
- Journal Title
  
  European Polymer Journal
  
  Volume: 147(15) Pages: 110325-110335
- DOI
  10.1016/j.eurpolymj.2021.110325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05327
[Journal Article] Construction of a polyMOF using a polymer ligand bearing the benzenedicarboxylic acid moiety in the side chain2020
- Author(s)
  Yazaki Kohei、Takahashi Masaki、Miyajima Naoya、Obata Makoto
- Journal Title
  
  New Journal of Chemistry
  
  Volume: 44 Issue: 14 Pages: 5182-5185
- DOI
  10.1039/c9nj06394c
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15535, KAKENHI-PROJECT-17K05877, KAKENHI-PROJECT-17K14482
[Journal Article] Synthesis of an oxygen-permeable block copolymer with catechol groups and its application in polymer-ceramic pressure-sensitive paint2020
- Author(s)
  Obata Makoto、Yamai Kouta、Takahashi Masaki、Ueno Shintaro、Ogura Hiroya、Egami Yasuhiro
- Journal Title
  
  Polymer
  
  Volume: 191 Pages: 122281-122281
- DOI
  10.1016/j.polymer.2020.122281
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05877, KAKENHI-PROJECT-17K06171, KAKENHI-PROJECT-17K14482
[Journal Article] A novel approach to white-light emission using a single fluorescent urea derivative and fluoride2019
- Author(s)
  Takahashi Masaki、Enami Yusuke、Ninagawa Hayato、Obata Makoto
- Journal Title
  
  New Journal of Chemistry
  
  Volume: 43 Issue: 8 Pages: 3265-3268
- DOI
  10.1039/c8nj05105d
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05877, KAKENHI-PROJECT-17K14482
[Journal Article] Synthesis, Photophysical Properties, and Photodynamic Activity of Positional Isomers of TFPP-Glucose Conjugates2018
- Author(s)
  Arif Fadlan, Hiroki Tanimoto, Tatsuya Ito, Yusuke Aritomi, Maho Ueno, Masaya Tokuda, *Shiho Hirohara, Makoto Obata, Tsumoru Morimoto, Kiyomi Kakiuchi
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 8 Pages: 1848-1858
- DOI
  10.1016/j.bmc.2018.02.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K17856, KAKENHI-PROJECT-17K05877
[Journal Article] Evaluation of the performance of glycosylated porphyrin platinum complex as an X-ray sensitizer2018
- Author(s)
  Tomomi Kubo, Ayano Hashimoto, Kohei Sharyo, Makoto Obata, Masato Tamura, Hirofumi Matsui, Shiho Hirohara
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: 7(2) Pages: 13-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05327
[Journal Article] Click Synthesis of Tetraphenylporphyrin Derivatives bearing 2-Deoxy-2-iodo-D-glucose as an FDG Analogue for Photodynamic Therapy2018
- Author(s)
  Shiho Hirohara, Keigo Uda, Tomomi Kubo, Masao Tanihara, Hirofumi Matsui, Makoto Obata, Kiyomi Kakiuchi
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: 7(2) Pages: 25-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05327
[Journal Article] RAFT synthesis of polystyrene-block-poly(polyethylene glycol monomethyl ether acrylate) for zinc phthalocyanine-loaded polymeric micelles as photodynamic therapy photosensitizers2017
- Author(s)
  Obata Makoto、Tanaka Shuto、Mizukoshi Hiroshi、Ishihara Eika、Takahashi Masaki、Hirohara Shiho
- Journal Title
  
  Journal of Polymer Science Part A: Polymer Chemistry
  
  Volume: 56 Issue: 5 Pages: 560-570
- DOI
  10.1002/pola.28929
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05877, KAKENHI-PROJECT-17K14482
[Journal Article] Synthesis of Amphiphilic Block Copolymer consisting of Glycopolymer and Poly(L-lactide) and Preparation of Sugar-coated Polymer Aggregates2016
- Author(s)
  M. Obata, R. Otobuchi, T. Kuroyanagi, M. Takahashi, S. Hirohara
- Journal Title
  
  J. Polym. Sci. Part A: Polym. Chem.
  
  Volume: 55 Issue: 3 Pages: 395-403
- DOI
  10.1002/pola.28401
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26410189
[Journal Article] Syntheses, photophysical properties, and photocytotoxicities of tetrakis(fluorophenyl)porphyrin derivatives bearing 2-hydroxyethylthio groups2016
- Author(s)
  M. Obata, S. Hirohara
- Journal Title
  
  J. Photochem. Photobiol. B: Biol.
  
  Volume: 162 Pages: 324-331
- DOI
  10.1016/j.jphotobiol.2016.07.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26410189
[Journal Article] Effect of polymer matrix on the performance of pressure-sensitive paint comprising 5,10,15,20-tetrakis (pentafluorophenyl)porphinato platinum(II) and poly(1,1,1,3,3,3-hexafluoroisopropyl-co- tert-butyl methacrylates)2015
- Author(s)
  M. Obata, R. Asato, S. Hirohara, K. Mitsuo
- Journal Title
  
  J. Appl. Polym. Sci.
  
  Volume: ｘｘｘ Issue: 16
- DOI
  10.1002/app.43316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26410189, KAKENHI-PROJECT-25410126
[Journal Article] RAFT Synthesis of Statistical and Block Copolymers of 2-(α-D-Mannopyranosyloxy)ethyl Methacrylate with 2-(N,N-Dimethylamino)ethyl Methacrylate and Application for Nonviral Gene Delivery2015
- Author(s)
  Makoto Obata, Tomoya Kobori, Shiho Hirohara, Masao Tanihara
- Journal Title
  
  Polymer Chemistry
  
  Volume: 6 Issue: 10 Pages: 1793-1804
- DOI
  10.1039/c4py01652a
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25410126, KAKENHI-PROJECT-26410189
[Journal Article] Synthesis, Photophysical Properties, and Biological Evaluation of trans-Bisthioglycosylated Tetrakis(fluorophenyl)chlorin for Photodynamic Therapy2015
- Author(s)
  S. Hirohara, C. Oka, M. Totani, M. Obata, J. Yuasa, H. Ito, M. Tamura, H. Matsui, K. Kakiuchi, T. Kawai, M. Kawaichi, M. Tanihara
- Journal Title
  
  J. Med. Chem.
  
  Volume: 58 Issue: 21 Pages: 8658-8670
- DOI
  10.1021/acs.jmedchem.5b01262
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410189, KAKENHI-PROJECT-14J07186, KAKENHI-PROJECT-25410126
[Journal Article] Synthesis and PDT Effect of Polysaccharide-conjugated Porphyrins2014
- Author(s)
  Shiho Hirohara, Kohei Sharyo, Makoto Obata, Hayato Akahoshi, Masahiro Shiraishi, Kyosuke Fujitsu, Naoto Akiyama, Kenji Sugimoto, Kenji, Yoichi Nakano, Masato Tamura, Hirofumi Matsui and Masao Tanihara
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: 3(1) Pages: 11-21
- NAID
  40020244921
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26410189
[Journal Article] Synthesis of Fluoroporphyrin comprising Glucose and Ethylene Glycol and Evaluation of Its Photodynamic Effect2014
- Author(s)
  Shiho Hirohara, Masahiro Shiraishi, Naoto Akiyama, Makoto Obata, Masato Tamura, Hiromu Ito, Hirofumi Matui, Kiyomi Kakiuchi
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: 3(2) Pages: 61-69
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26410189
[Journal Article] Radical Polymerization of Trifluoromethyl- substituted Methyl Methacrylates and Their Application for Use in Pressure-Sensitive Paint2013
- Author(s)
  M.Obata, R.Asato, K. Mitsuo, S. Hirohara
- Journal Title
  
  J. Polym. Sci. Part A: Polym. Chem.
  
  Volume: 52 Issue: 7 Pages: 963-972
- DOI
  10.1002/pola.27076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750192, KAKENHI-PROJECT-25410126
[Journal Article] Trans-Bisglyco- conjugation is an Efficient and Robust Architecture for PDT Photosensitizers based on 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin Derivatives2013
- Author(s)
  S. Hirohara, K. Sharyo, Y. Kawasaki, M. Totani, A. Tomotsuka, R. Funasako, N. Yasui, Y. Hasegawa, J. Yuasa, T. Nakashima, T. Kawai, C. Oka, M. Kawaichi, M. Obata, M. Tanihara
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 86 Issue: 11 Pages: 1295-1308
- DOI
  10.1246/bcsj.20130131
- NAID
  130004153161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750192, KAKENHI-PROJECT-25410126
[Journal Article] Syntheses of 3-Arm and 4-Arm Star-Branched Polystyrene Ru(II) Complexes by the Click-to-Chelate Approach2011
- Author(s)
  Chunhong Zhang, Xiande Shen, Ryosuke Sakai, Michael Gottschaldt, Ulrich S. Schubert, Shiho Hirohara, Masao Tanihara, Shigenobu Yano, Makoto Obata, Nao Xiao, Toshifumi Satoh, Toyoji Kakuchi
- Journal Title
  
  J. Polym. Sci. Part A : Polym. Chem.
  
  Volume: 49 Pages: 746-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Characterization and Cellular Internalization of Poly(2-hydroxyethyl methacrylate) bearing.-D-Mannopyranose2011
- Author(s)
  Makoto Obata, Mayumi Shimizu, Tomoko Ohta, Aya Matsushige, Kaoru Iwai, Shiho Hirohara, Masao Tanihara, Synthesis
- Journal Title
  
  Polym. Chem.
  
  Volume: 2 Pages: 651-658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Current states and future views in photodynamic therapy2011
- Author(s)
  Shigenobu Yano, Shiho Hirohara, Makoto Obata, Yuichiro Hagiya, Shun-ichiro Ogura, Atsushi Ikeda, Hiromi Kataoka, Mamoru Tanaka, Takashi Joh
- Journal Title
  
  J. Photochem. Photobiol. C, Photochem. Rev.
  
  Volume: 12 Pages: 46-67
- NAID
  10029471944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Synthesis, Characterization and Cellular Internalization of Poly(2-hydroxyethyl methacrylate bearing α-D-Mannopyranose2011
- Author(s)
  Makoto Obata
- Journal Title
  
  Polymer Chemistry
  
  Volume: 2 Pages: 651-658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Michael Gottschaldt, Aram Prokop, Mitochondrial mode of action of a thymidine-based cisplatin analog breaks resistance in cancer cells2010
- Author(s)
  Liliane A. Onambele, Daniel Koth, Justyna A. Czaplewska, Ulrich S. Schubert, Helmar Gorls, Shigenobu Yano, Makoto Obata
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 16 Pages: 14498-14505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Synthesis, Photophysical Properties and Photocytotoxicity of Mono-, Di-, Tri-and Tetra-Glucosylated Fluorophyenylporphyrins2010
- Author(s)
  Shiho Hirohara, Masataka Nishida, Kohei Sharyo, Makoto Obata, Tsuyoshi Ando, Masao Tanihara
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 18 Pages: 1526-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Plasmon-Enhanced Luminescence from Ultrathin Hybrid Polymer Nanoassemblies for Microscopic Oxygen Sensor Application2010
- Author(s)
  Masaya Mitsuishi, Hiroyuki Tanaka, Makoto Obata, Tokuji Miyashita
- Journal Title
  
  Langmuir
  
  Volume: 26 Pages: 15117-15120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Oxygen-Sensing Properties of 5, 10, 15, 20-Tetraphenylporphinato Platinum(II) and Palladium(II) Covalently Bound on Poly(isobutyl-co-2, 2, 2-trifluoroethyl methacrylate)2010
- Author(s)
  Makoto Obata
- Journal Title
  
  Journal of Polymer Science Part A : Polymer Chemistry 48
  
  Pages: 663-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Oxygen-Sensing Properties of 5, 10, 15, 20-Tetraphenylporphinato Platinum(II) and Palladium(II) Covalently Bound on Poly(isobutyl-co-2, 2, 2-trifluoroethyl methacrylate2010
- Author(s)
  Makoto Obata, Noriko Matsuura, Kazunori Mitsuo, Hiroki Nagai, Keisuke Asai, Masafumi Harada, Shiho Hirohara, Masao Tanihara, Shigenobu Yano
- Journal Title
  
  J. Polym. Sci. Part A : Polym. Chem.
  
  Volume: 48 Pages: 663-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Mitochondrial mode of action of a thymidine-based cisplatin analog breaks resistance in cancer cells2010
- Author(s)
  L.A.Onambele, D.Koth, J.A.Czaplewska, Ul.S.Schubert, H.Gorls, S.Yano, M.Obata, M.Gottschaldt, A.Prokop
- Journal Title
  
  Eur.J.Chem. 16
  
  Pages: 14498-14505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Synthesis and Photocytotoxicity of S-Glucosylated 5,10,15,20-Tetrakis(tetrafluorophenyl)porphyrin Metal Complexes as Efficient 1O2-Generating Glycoconjugates2009
- Author(s)
  Shiho, Hirohara, Makoto, Obata, Hiroki, Alitomo, Kohei, Sharyo, Tsuyoshi, Ando, Shigenobu, Yano, Masao, Tanihara
- Journal Title
  
  Bioconjugate Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] In Vitro Heavy-Atom Effect of Palladium (II) and Platinum (II) Complexes of Pyrrolidine-Fused Chlorin in Photodynamic Therapy2009
- Author(s)
  M.Obata
- Journal Title
  
  J.Med.Chem. 52
  
  Pages: 2747-2753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] In Vitro Heavy-Atom Effect of Palladium(II)and Platinum(II)Complexes of Pyrrolidine-Fused Chlorin in Photodynamic Therapy,2009
- Author(s)
  Makoto, Obata, Shiho, Hirohara, Rika, Tanaka, Isamu, Kinoshita, Kei, Ohkubo, Shunichi, Fukuzumi, Masao, Tanihara, Shigenobu, Yano
- Journal Title
  
  J. Med. Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] EXAFS Study on Reaction of Anti-tumor Platinum Complexes with Reduced Glutathione2009
- Author(s)
  Makoto Obata, Masafumi Harada, Hiromi Ohi, Shiho Hirohara, Michael Gottchaldt, Shigenobu Yano
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 57 Pages: 1107-1109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] EXAFS Study on Reaction of Anti-tumor Platinum Complexes with Reduced Glutathione2009
- Author(s)
  M.Obata, M.Harada, H.Ohi, S.Hirohara, M.Gottchaldt, S.Yano
- Journal Title
  
  Chem.Pharm.Bull. 57
  
  Pages: 1107-1109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Synthesis, photophysical properties and sugar-dependent in vitro photocytotoxicity of pyrrolidine-fused chlorins bearing S-glycosides2009
- Author(s)
  Shiho Hirohara, Makoto Obata, Hiroki Alitomo, Kohei Sharyo, Tsuyoshi Ando, Masao Tanihara, Shigenobu Yano
- Journal Title
  
  J. Photochem. Photobiol. B, Biol.
  
  Volume: 97 Pages: 22-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] In Vitro Heavy-Atom Effect of Palladium(II)and Platinum(II)Complexes of Pyrrolidine-Fused Chlorin in Photodynamic Therapy2009
- Author(s)
  M. OBATA
- Journal Title
  
  J. Med. Chem (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Synthesis, Photophysical Properties and Sugar-Dependent In Vitro Photocytotoxicity of Pyrrolidine-Fused Chlorins bearing S-Glycosides2009
- Author(s)
  S.Hirohara, M.Obata, H.Alitomo, K.Sharyo, T.Ando, M.Tanihara, S.Yano
- Journal Title
  
  J.Phtochem. Photobiol, B : Biol. 97
  
  Pages: 22-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] In Vitro Heavy-Atom Effect of Palladium (II) and Platinum (II) Complexes of Pyrrolidine-Fused Chlorin in Photodynamic Therapy2009
- Author(s)
  M.Obata, S.Hirohara, R.Tanaka, I.Kinoshita, K.Ohkubo, S.Fukuzumi, M.Tanihara, S.Yano
- Journal Title
  
  J.Med.Chem. 52
  
  Pages: 2747-2753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Antioxidant action of sugar-pendant C60 fullerenes2009
- Author(s)
  Masanori Horie, Akiko Fukuhara, Yoshiro Saito, Yasukazu Yoshida, Hiroe Sato, Hiromi Ohi, Makoto Obata, Yuji Mikata, Shigenobu Yano, Etsuo Niki
- Journal Title
  
  Bioorg Med. Chem. Lett.
  
  Volume: 19 Pages: 5902-5904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550156
[Journal Article] Synthesis and Photocytotoxicity of S-Glucosylated 5,10,15,20-Tetrakis(tetrafluorophenyl)porphyrin Metal Complexes as Efficient 1^<O>_2-Generating Glycoconjugates2009
- Author(s)
  S.Hirohara, M.Obata, H.Alitomo, K.Sharyo, T.Ando, S.Yano, M.Tanihara
- Journal Title
  
  Bioconjugate Chem. 20
  
  Pages: 944-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Synthesis, Photophysical Properties and Sugar-Dependent In Vitro Photocytotoxicity of Pyrrolidine-Fused Chlorins bearing S-Glycosides2009
- Author(s)
  S. Hirohara, M. Obata, H. Alitomo, K. Sharyo, S. Yano, 7番日, 他2名
- Journal Title
  
  J. Phtochem. Photobiol, B : Biol. 97
  
  Pages: 22-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] In Vitro Heavy-Atom Effect of Palladium (II) and Platinum (II) Complexes of Pyrrolidine-Fused Chlorin in Photodynamic Therapy2009
- Author(s)
  M. Obata, S. Hirohara, R. Tanaka, I. Kinoshita, 8番日, 他4名
- Journal Title
  
  J.Med.Chem. 52
  
  Pages: 2747-2753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Syntheses, structural characterization and photophysical properties of 4-(2-pyridyl)-1, 2, 3-triazole rhenium (I) complexes2008
- Author(s)
  M.Obata, A.Kitamura, A.Mori, C.K.J.A.Czaplewska, R.Tanaka, I Kinoshita, T.Kusumoto, H.Hashimoto, M.Harada, Y.Mikata, T.Funabiki, S.Yano
- Journal Title
  
  Dalton Trans.
  
  Pages: 3292-3300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Syntheses, structural characteriza tion and photophysical properties of 4-(2-pyridyl)-1, 2, 3- triazole rhenium (I) complexes2008
- Author(s)
  M. Obata, A. Kitamura, A. Mori, C. K. J. A. Czaplewska, 12番日, 他7名
- Journal Title
  
  Dalton Trans.
  
  Pages: 3292-3300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Structure-Photodynamic Effect Relationships of 24 Glycoconjugated Photosensitizers in HeLa Cells2008
- Author(s)
  S.Hirohara, M.Obata, H.Alitomo, K.Sharyo, S.Ogata, C.Ohtsuki, S.Yano, T.Ando, M.Tanihara
- Journal Title
  
  Biol.Pharm. Bull. 31
  
  Pages: 2265-2272
- NAID
  110007005027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Syntheses, structural characterization and photophysical properties of 4-(2-pyridyl)-l, 2, 3-triazole rhenium(I)complexes2008
- Author(s)
  M. Obata
- Journal Title
  
  Dalton Transactions 25
  
  Pages: 2392-3300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Structure-Photodynamic Effect Relationships of 24 Glycoconjugated Photosensitizers in HeLa Cells2008
- Author(s)
  Shiho, Hirohara, Makoto, Obata, Hiroki, Alitomo, Kohei, Sharyo, Shin-ichi, Ogata, Chikara, Ohtsuki, Shigenobu, Yano, Tsuyoshi, Ando, Masao, Tanihara
- Journal Title
  
  Biol. Pharm. Bull. 31
  
  Pages: 2265-2272
- NAID
  110007005027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Synthesis and Photophysical Properties of Rhodamine B Dye-bearing Poly(isobutylmethacrylate-co-2,2,2-trifluoroethyl methacrylate)as a Temperature-Sensing Polymer Film2007
- Author(s)
  M. Obata
- Journal Title
  
  J. Polym. Sci. Part A Chemistry 45
  
  Pages: 2876-2885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Sugar-dependent photodynamic effect of glycoconjugated porphyrins : A study on photocytotoxicity, photophysical properties and binding behavior to bovine serum albumin (BSA)2007
- Author(s)
  M.Obata, S.Yano, 他7名
- Journal Title
  
  Biochim. Biophys. Acta 1770
  
  Pages: 1204-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Journal Article] Optical oxygen-sensing properties of porphyrin derivatives anchored on ordered porous aluminium oxide plates2007
- Author(s)
  Naoko, Araki, Yutaka, Amao, Takuzo, Funabiki, Masanobu, Kamitakahara, Chikara, Ohtsuki, Kazunori, Mitsuo, Keisuke, Asai, Makoto, Obata, Shigenobu, Yano
- Journal Title
  
  Photochem. Photobiol. Sci. 6
  
  Pages: 794-803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Synthesis and Photophysical Properties of Rhodamine B Dye-bearing Poly(isobutyl methacrylate-co-2,2,2-trifluoroethyl methacrylate) as a Temperature-Sensing Polymer Film"2007
- Author(s)
  Makoto, Obata, Mako, Morita, Kayoko, Nakase, Kazunori, Mitsuo, Keisuke, Asai, Shiho, Hirohara, Shigenobu, Yano
- Journal Title
  
  J. Polym. Sci. A Chem 45
  
  Pages: 2876-2885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Sugar-dependent photodynamic effect of glycoconjugated porphyrins: A study on photocytotoxicity, photophysical properties and binding behavior to bovine serum albumin(BSA)2007
- Author(s)
  M. Obata
- Journal Title
  
  Biochimica et Biophysica Acta, General Subjects, 1770
  
  Pages: 1204-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Properties of Rhodamine B Dye-bearing Poly(isobutylmethacrylate-co-2,2,2-trifluoroethyl methacrylate) as a Temperature-Sensing Polymer Film2007
- Author(s)
  M.Obata
- Journal Title
  
  J. Polym. Sci. Part A : Poly. Chem. (in press)
- Data Source
  KAKENHI-PROJECT-17029040
[Journal Article] Sugar-dependent photodynamic effect of glycoconjugated porphyrins : A study on photocytotoxicity, photophysical properties and binding behavior to bovine serum albumin(BSA)2007
- Author(s)
  Makoto, Obata, Shiho, Hirohara, Kohei, Sharyo, Hiroki, Alitomo, Kazumi, Kajiwara, Shin-ichi, Ogata, Masao, Tanihara, Chikara, Ohtsuki, Shigenobu, Yano
- Journal Title
  
  Biochim. Biophys. Acta 1770
  
  Pages: 1204-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19614009
[Journal Article] Novel Oxygen Chirality Induced by Asymmetric Coordination of Oxygen Atom to a Metal Center in a Series of Sugar-pendant Dipicolylamine-Copper (II) Complexes2006
- Author(s)
  Y.Mikata, Y.Sugai, M.Obata, M.Harada, S.Yano
- Journal Title
  
  Inorg. Chem. 45
  
  Pages: 1543-1551
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350032
[Journal Article] Silver (I) complexes based on novel tripodal thioglycosides : synthesis, structure and antimicrobial activity2006
- Author(s)
  M.Gottschaldt, A.Pfeifer, H.Gorls, M.Obata, S.Yano
- Journal Title
  
  Tetrahedron 62
  
  Pages: 11073-11080
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350032
[Journal Article] Cellular Uptake and Photocytotoxicity of Glycoconjugated Chlorins in HeLa Cells2005
- Author(s)
  S.Hirohara, M.Obata, S.Ogata, C.Ohtsuki, S.Higashida, S.Ogura, I.Okura, M.Takenaka, H.Ono, YSugai, Y.Mikata, M.Tanihara, S.Yano
- Journal Title
  
  J. Photochem. Photobiol. B, Biology 78
  
  Pages: 7-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350032
[Journal Article] Synthesis and Insulin-mimetic Activities of Metal Complexes with 3-Hydroxypyridine-2-carboxylic Acid2005
- Author(s)
  M.Nakai, F.Sekiguchi, M.Obata, C.Ohtsuki, Y.Adachi, H.Sakurai, C.Orvig, D.R.Rehder, S.Yano
- Journal Title
  
  J. Inorg. Biochem. 6
  
  Pages: 1275-1282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350032
[Journal Article] Synthesis Structural Characterization, and Antitumor Activity of Palladium (II) Complexes Containing a Sugar Unit2004
- Author(s)
  I.Brudzinska, Y.Mikata, M.Obata, C.Ohtsuki, S.Yano
- Journal Title
  
  Bioorg. Med. Chem. Lett. 14(10)
  
  Pages: 2533-2536
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350032
[Journal Article] Electro- and photochemical properties of (μ-alkoxo)bis(μ-carboxylato)diruthenium complex having two tetraphenylporphinato zinc(II) moieties2004
- Author(s)
  M.Obata
- Journal Title
  
  Dalton Transactions
  
  Pages: 3283-3287
- Data Source
  KAKENHI-PROJECT-16350032
[Journal Article] Electro- and photochemical properties of (μ-alkoxo)bis(t-carboxylato)diruthenium complex having two tetraphenylporphinato zinc(II) moietie2004
- Author(s)
  M.Obata
- Journal Title
  
  Dalton Transactions
  
  Pages: 3283-3287
- Data Source
  KAKENHI-PROJECT-15033246
[Journal Article] Synthesis of Poly(isobutyl-co-2,2,2-trifluoroetyl methacrylate) having 5,10,15,20-tetraphenylporphinato platinum(II) (PtTPP) Moiety as an Oxygen-sensing Dye for Pressure-Sensit
- Author(s)
  M.Obata
- Journal Title
  
  J.Polym.Sci., Part A, Chemistry (in press)
- Data Source
  KAKENHI-PROJECT-15033246
[Journal Article] Current states and future views in photodynamic therapy
- Author(s)
  S.Yano, S.Hirohara, M.Obata, Y.Hagiya, S.Ogura, A.Ikeda, H.Kataoka, M.Tanaka, T.Joh
- Journal Title
  
  J.Photochem. Photobiol., C (in press)
- NAID
  10029471944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350031
[Patent] 両親媒性ブロック共重合体2020
- Inventor(s)
  廣原志保、小幡誠
- Industrial Property Rights Holder
  廣原志保、小幡誠
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-151697
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K05327
[Presentation] AIEを利用した高分子ミセルへの低分子内包挙動の解析の試み2023
- Author(s)
  木部泰希、小幡誠
- Organizer
  第72回高分子討論会
- Data Source
  KAKENHI-PROJECT-23K04854
[Presentation] 重合後修飾によるアミノクリル酸エステル構造を有する両親媒性ブロックコポリマーの合成2019
- Author(s)
  桑田薫、小幡誠
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-17K05877
[Presentation] ２つの置換基を持つクロリンの物性評価2016
- Author(s)
  廣原志保、小幡誠、松井裕史、垣内喜代三
- Organizer
  第６回ポルフィリンALA学会
- Place of Presentation
  東京大学・医科学研究所
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] Mn ポルフィリンの合成と物性評価2016
- Author(s)
  松村神奈、小幡誠、松井裕史、廣原志保
- Organizer
  第６回ポルフィリンALA学会
- Place of Presentation
  東京大学・医科学研究所
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] 2つの置換基を有するフッ素クロリンの光細胞毒性2016
- Author(s)
  廣原志保、小幡誠、松井裕史、垣内喜代三
- Organizer
  第２６回日本光線力学学会学術講演会（シンポジウム：フォトダイナミックセラノスティクスのためのポルフィリン薬剤の創成）
- Place of Presentation
  はまぎんホールヴィアマーレ（横浜）
- Year and Date
  2016-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] 抗酸化剤としてのポルフィリン金属錯体の合成と評価2016
- Author(s)
  松村神奈、小幡誠、伊藤紘、松井裕史、廣原志保
- Organizer
  第31回日本酸化ストレス学会関東部会
- Place of Presentation
  芝浦工業大学　豊洲キャンパス
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] メルカプトエタノール連結クロリンの合成とPDT評価2016
- Author(s)
  井町美晴、松村神奈、廣原志保、小幡誠、松井裕史
- Organizer
  第31回日本酸化ストレス学会関東部会
- Place of Presentation
  芝浦工業大学　豊洲キャンパス
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] 光増感剤のための高分子キャリアの精密合成2016
- Author(s)
  小幡誠、筒井雄也、廣原志保
- Organizer
  第２６回日本光線力学学会学術講演会（シンポジウム：フォトダイナミックセラノスティクスのためのポルフィリン薬剤の創成）
- Place of Presentation
  はまぎんホールヴィアマーレ（横浜）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] PDT effect of TFPP derivatives having two different functional groups2015
- Author(s)
  S. Hirohara, Y. Kubota, N. Akiyama, M. Obata, H. Matsui, K. Kakiuchi
- Organizer
  The 3rd International ALA and Porphyrin Symposium (IAPS3)
- Place of Presentation
  Hawai
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] Synthesis and characterization of water-soluble polymers bearing porphyrin moiety at the initiating end for photodynamic therapy2015
- Author(s)
  M. Obata, Y. Tsutsui, S. Hirohara
- Organizer
  Pacifichem 2015
- Place of Presentation
  Bench to Bedside: Chemistry of Health Care, Hawai
- Year and Date
  2015-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] Synthesis and characterization of water-soluble polymers bearing porphyrin moiety at the initiating end for photodynamic therapy2015
- Author(s)
  Makoto Obata, Yuya Tsutsui, Shiho Hirohara
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawai, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] 二つの水溶性置換基を有するポルフィリン誘導体の合成とin vitro評価2015
- Author(s)
  廣原志保, 小幡誠, 松井裕史, 垣内喜代三
- Organizer
  第25回日本光線力学学会
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] RAFT重合によるカチオン性糖質高分子の合成と核酸キャリアへの応用2015
- Author(s)
  小幡誠、小堀智也、廣原志保、谷原正夫
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都・新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] RAFT polymerization of HPMA using chain transfer agent bearing porphyrin moiety2015
- Author(s)
  Yuya Tsutsui, Makoto Obata
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawai, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] ポルフィリン連結連鎖移動剤の合成とN-(2-ヒドロキシプロピル)メタクリルアミドのRAFT重合2015
- Author(s)
  筒井雄也、小幡誠
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学川内キャンパス（宮城県・仙台市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] Synthesis and photocytotoxicity of fluorophyenylporphyrin derivatives having two different functional groups2015
- Author(s)
  S. Hirohara, Y. Kubota, N. Akiyama, M. Obata, H. Matsui, K. Kakiuchi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Bench to Bedside: Chemistry of Health Care, Hawai
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] RAFT重合とクリック反応によるポリ(L-リシン)と糖質高分子のブロックコポリマーの合成2015
- Author(s)
  水越洋、小幡誠
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学川内キャンパス（宮城県・仙台市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] ２つの置換基を有するフッ素クロリンの合成と物性評価2014
- Author(s)
  秋山直澄, 窪田雄介, 廣原志保, 小幡誠, 松井裕史, 谷本裕樹, 垣内喜代三
- Organizer
  第29 回日本酸化ストレス学会関東支部会
- Place of Presentation
  東京
- Year and Date
  2014-12-20
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] ポルフィリン金属錯体のX線感受性試験2014
- Author(s)
  廣原志保, 田村磨聖, 松井裕史, 小幡誠
- Organizer
  第4回ポルフィリンALA学会
- Place of Presentation
  神戸
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] グルコース連結クロリンのPDT評価2014
- Author(s)
  廣原志保, 谷原正夫, 岡千緒, 川市正史, 垣内喜代三, 小幡誠, 松井裕史
- Organizer
  第29 回日本酸化ストレス学会関東支部会
- Place of Presentation
  東京
- Year and Date
  2014-12-20
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] RAFT重合法によるカチオン性セグメントを有する糖質高分子の合成2013
- Author(s)
  張磊、小幡誠
- Organizer
  第62回高分子討論会
- Place of Presentation
  金沢大学角間キャンパス
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] カチオン性分岐糖質高分子の合成と核酸キャリアへの応用2013
- Author(s)
  森越洋行、小幡誠
- Organizer
  第62回高分子討論会
- Place of Presentation
  金沢大学角間キャンパス
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] カチオン性セグメントを有する糖質高分子の合成とポリプレックス形成2012
- Author(s)
  小幡誠,小堀智也
- Organizer
  第92回日本化学会春季年会
- Place of Presentation
  慶應義塾大学日吉キャンパス・矢上キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] カチオン性セグメントを有する糖質高分子の合成とポリプレックス形成2012
- Author(s)
  小幡誠、小堀智也
- Organizer
  第92回日本化学会春季年会
- Place of Presentation
  慶應義塾大学(横浜市)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] マンノピラノシル基を有するメタクリル酸エステルの合成と重合およびその細胞内取り込み2011
- Author(s)
  小幡誠,太田智子,廣原志保,谷原正夫
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] マンノースを側鎖に有するカチオン性糖質高分子の合成とその性質2011
- Author(s)
  小幡誠,小堀智也
- Organizer
  第60回高分子討論会
- Place of Presentation
  岡山大学津島キャンパス
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] マンノピラノシル基を有するメタクリル酸エステルの合成と重合およびその細胞内取り込み2011
- Author(s)
  小幡誠, 他3名
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] カチオン性糖質高分子の合成とポリプレックス形成能2011
- Author(s)
  小幡誠、小堀智也
- Organizer
  第60回高分子討論会
- Place of Presentation
  岡山大学(岡山市)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] メタクリル酸2-(-D-マンノピラノシルオキシ)エチルとメタクリル酸2-ヒドロキシエチルのラジカル共重合2010
- Author(s)
  清水真弓,岩井薫,小幡誠
- Organizer
  第59回高分子年次大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] マンノースを側鎖に有する糖質高分子の合成と性質2010
- Author(s)
  小幡誠, 他4名
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪大学(大阪)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] マンノースを側鎖に有する糖質高分子の合成と性質2010
- Author(s)
  小幡誠,清水真弓,岩井薫,廣原志保,谷原正夫
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪大学豊中キャンパス
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] メタクリル酸2-(-D-マンノピラノシルオキシ)エチルとメタクリル酸ジメチルアミノエチルのラジカル共重合2010
- Author(s)
  小堀智也,小幡誠
- Organizer
  第59回高分子年次大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] メタクリル酸マンノピラノシルオキシエチルとメタクリル酸ジメチルアミノエチルのラジカル共重合2010
- Author(s)
  小幡誠
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学,大阪
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] メタクリル酸マンノピラノシルオキシエチルとメタクリル酸ジメチルアミノエチルのラジカル共重合2010
- Author(s)
  小幡誠
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21550156
[Presentation] Syntheses and Applications of Polymeric Materials having Photosensitizing Functionality, The 12th World Multi-Conference on Systemics, Cybernetics and Informatics2008
- Author(s)
  Makoto Obata
- Organizer
  Advanced Nanomaterials New Concepts and Technologies - Invited Session I
- Place of Presentation
  Rosen Centre Hotel (Orland, Florida, USA)
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] 光線力学療法用糖連結フッ素ポルフィリン誘導体の合成とその光毒性2008
- Author(s)
  佐久間志帆, 廣原志保, 谷原正夫, 小幡誠, 三方裕司, 船引卓三, 矢野重信
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] フッ素ポルフィリンのリビングラジカル重合による糖質高分子の合成と光線力学療法への応用2008
- Author(s)
  大竹絵依子, 廣原志保, 谷原正夫, 小幡誠, 三方裕司, 船引卓三, 矢野重信
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] Syntheses and Applications of Polymeric Materials having Photosensitizing Functionality2008
- Author(s)
  M. OBATA
- Organizer
  The 12th World Multi-Conference on Sstemics. Cybernetics and Informatics, Advanced Nanomaterials New Concepts and Technologies - Invited Session I
- Place of Presentation
  Rosen Centre Hotel(Orland, Florida, USA)
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] クロリン環を光増感部位として有する糖質高分子の合成と光線力学療法への応用2008
- Author(s)
  小幡誠, 大竹絵依子, 廣原志保, 谷原正夫, 矢野重信
- Organizer
  第3回バイオ関連化学合同シンポジウム(第23回生体機能関連化学シンポジウム)
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] 糖分子を機能素子とするフッ素クロリン誘導体の合成と光細胞毒性2007
- Author(s)
  小幡誠, 廣原志保, 谷原正夫, 田中里佳, 木下勇, 大久保敬, 福住俊一, 矢野重信
- Organizer
  第22回生体機能関連化学シンポジウム
- Place of Presentation
  東北大学
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] SYNTHESIS OF POLYMERS HAVING PHOTOSENSITIZING MOIETIES FORPRESSURE/TEMPERATURE-SENSITIVE PAINT AND PHOTODYNAMIC THERAPY2007
- Author(s)
  M. Obata
- Organizer
  International Symposium on Advanced Macromolecules and Nano-materials with Precisely Designed Architectures
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] フッ素クロリン金属錯体の光化学的性質と光線力学療法への応用2007
- Author(s)
  小幡誠, 廣原志保, 谷原正夫, 田中里佳, 木下勇, 大久保敬, 福住俊一, 矢野重信
- Organizer
  第20回配位化合物の光化学討論会
- Place of Presentation
  シーサイドホテル舞子ビラ神戸
- Year and Date
  2007-08-07
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] Synthesis of Glycoconjugated Fluorochlorin Derivatives and Their Application for Photodynamic Therapy (PDT)2007
- Author(s)
  Shiho, Sakuma, Makoto, Obata, Yuji, Mikata, Takuzo, Funabiki, Shigenobu, Yano
- Organizer
  14th International SPACC-CSJ Synposium
- Place of Presentation
  National Taiwan University (Taipei, Taiwan)
- Year and Date
  2007-12-20
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] Synthesis of Polymers having Photosensitizing Moieties for Pressure/Temperature-Sensitive Paint and Photodynamic Therapy2007
- Author(s)
  Makoto, Obata, Kazunori, Mitsuo, Hiroki, Nagai, Keisuke, Asai, Kazue, Wakashi, Shiho, Hirohara, Masao, Tanihara, Atsushi, Narumi, Toyoji, Kakuchi, Shigenobu, Yano
- Organizer
  International Symposium on Advanced Macromolecules and Nano-materials with Precisely Designed Architectures
- Place of Presentation
  Hokkaido University
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] Synthesis, Characterization and In Vitro Photocytotoxicity of Novel Fluorinated Metallochlorins for Photodynamic Therapy Photosensitizers2007
- Author(s)
  Makoto, Obata, Shiho, Hirohara, Masao, Tanihara, Rika, Tanaka, Isamu, Kinoshita, Kei, Ohkubo, Shunichi, Fukuzumi, Shigenobu, Yano
- Organizer
  14th International SPACC-CSJ Synposium
- Place of Presentation
  National Taiwan University (Taipei, Taiwan)
- Year and Date
  2007-12-20
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] Novel Approach for the Synthesis of Fluorochlorin Derivatives by Radical Addition and Their Application for Photodynamic Therapy (PDT)2007
- Author(s)
  Eiko, Otake, Makoto, Obata, Yuji, Mikata, Takuzo, Funabiki, Shigenobu, Yano
- Organizer
  14th International SPACC-CSJ Synposium
- Place of Presentation
  National Taiwan University(Taipei, Taiwan)
- Year and Date
  2007-12-20
- Data Source
  KAKENHI-PROJECT-19614009
[Presentation] メルカプトエタノールを連結したフッ素ポルフィリンの合成と光細胞毒性
- Author(s)
  小幡誠, 廣原志保
- Organizer
  第24回日本光線力学学会
- Place of Presentation
  静岡
- Year and Date
  2014-06-28 – 2014-06-29
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] DDSキャリアのためのポリ乳酸と糖質高分子からなるブロックコポリマーの合成
- Author(s)
  音淵良太、小幡誠
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] RAFT重合法によるカチオン性セグメントと糖質高分子からなるブロックコポリマーの合成
- Author(s)
  張磊、小幡誠
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] 核酸キャリアのためのポリ(L-リシン)と糖質高分子からなるブロックコポリマーの合成
- Author(s)
  森越洋行、小幡誠
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25410126
[Presentation] ２つの水溶性置換基を有するポルフィリン誘導体の開発
- Author(s)
  窪田雄介, 秋山直澄, 藤津恭介, 白石昌大, 赤星迅人, 小幡誠, 松井裕史, 廣原志保
- Organizer
  2014年日本化学会中国四国支部大会
- Place of Presentation
  山口
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] メルカプトエタノールとグルコースを有するクロリンの合成と細胞評価
- Author(s)
  秋山直澄, 窪田雄介, 藤津恭介, 白石昌大, 赤星迅人, 小幡誠, 松井裕史, 廣原志保
- Organizer
  2014年日本化学会中国四国支部大会
- Place of Presentation
  山口
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26410189
[Presentation] グルコース鎖とエチレングリコール鎖を用いたポルフィリンの合成と細胞評価
- Author(s)
  廣原志保, 白石昌大, 小幡誠, 松井裕史
- Organizer
  第24回日本光線力学学会
- Place of Presentation
  静岡
- Year and Date
  2014-06-28 – 2014-06-29
- Data Source
  KAKENHI-PROJECT-26410189

1. YANO Shigenobu (60011186)

# of Collaborated Projects: 6 results

# of Collaborated Products: 32 results
2. HIROHARA Shiho (70413804)

# of Collaborated Projects: 4 results

# of Collaborated Products: 33 results
3. MORIMOTO Keiko (30220081)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OOI Hiromi (80452522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. URUMA Yoshiyuki (70442457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AKASHI Haruo (30221708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIBAHARA Takashi (30122386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小倉俊一郎 (90343160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 谷本裕樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 矢崎晃平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OBATA Makoto 小幡 誠

小幡 誠 オバタ マコト

Research Projects

Research Products

Co-Researchers

Study on polymer-drug interaction by AIE technique for polymer micelle designPrincipal Investigator

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Development of PET-BNCT dual-functional porphyrin for theranostics drugs

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Development of Boron Carrier for BNCT by Precision Polymerization TechniquePrincipal Investigator

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Development of water-soluble Zinc porphyrin aimed at Theranostics

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Precision Synthesis of Block Glycopolymers for DDS Carrier targeting MacrophagesPrincipal Investigator

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Synthesis of Cationic Glycopolymer and Development of Sugar-Coated Polyplex for Gene Delivery ApplicationPrincipal Investigator

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Development of Glycoconjugated Hybrid Metal Complexes for the Next-Generation Advanced Medical Care

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Development of Novel Photosensitizers having Biofunctional Moieties for QOL-oriented Photodynamic TherapyPrincipal Investigator

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分子性有機・無機複合型光機能性素子の開発と光機能界面への応用

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配位空間のナノ制御による光応答性金属クラスターの構築と新機能開発

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Development of Glycoconjugated Hybrid Metal Complexes toward Frontier Medicinal Treatment and Elucidation of their Biomechanism

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高度集積化複合色素を機能素子とする新規光機能性材料の技術開発

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立体規則性高分子をテンプレートとする光応答性ポルフィリン集積体の構築Principal Investigator

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OBATA Makoto 小幡誠

小幡誠オバタマコト