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HASHIMOTO Ken  橋本 研

ORCIDConnect your ORCID iD *help
Researcher Number 70343457
Other IDs
Affiliation (based on the past Project Information) *help 2007 – 2010: 明海大学, 歯学部, 助教
2009: 明海大学, 歯学部, 助教授
2004 – 2006: 明海大学, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Functional basic dentistry
Except Principal Investigator
Conservative dentistry / Functional basic dentistry
Keywords
Principal Investigator
歯周病 / マクロファージ / アスパラギン合成酵素
Except Principal Investigator
創傷治癒 / メカニズム / 修復象牙質 / Enamel Proteins / プレニルアルコール / ビタミンK_2 / ベンズアルデヒド誘導体 … More / 細胞のタイプ / 環状α,β-不飽和ケトン / 細胞間での感受性の差 / β不飽和ケトン / 環状α / 構造活性相関 / オートファジー / アポトーシス / 細胞死のタイプ / 口腔扁平上皮癌細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (5 People)
  •  A study of the mechanism of reparative dentin by Enamel Proteins.

    • Principal Investigator
      YUKIO Nakamura
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Meikai University
  •  Basic research for the development of autophagy-inducing therapy against human oral squamous cell carcinoma cell lines

    • Principal Investigator
      SAKAGAMI Hiroshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Meikai University
  •  歯周病によるマクロファージの活性化とアスパラギン合成酵素誘導Principal Investigator

    • Principal Investigator
      橋本 研
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Meikai University

All 2010 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] Steroidal glycosides from Furcraea foetida and their cytotoxic activity.2009

    • Author(s)
      Yokosuka A, Sano T, Hashimoto K, Sakagami H, Mimaki Y
    • Journal Title

      Chem Pharm Bull 57

      Pages: 1161-1166

    • NAID

      130000124800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Triterpene glycosides from the whole plant of Anemone hupehensis var. japonica and their cytotoxic activity.2009

    • Author(s)
      Yokosuka A, Sano T, Hashimoto K, Sakagami H, Mimaki Y
    • Journal Title

      Chem Pharm Bull 57

      Pages: 1425-1430

    • NAID

      130000124549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Type of cell death induced byα-trifluoromethyl acyloins in oral squamous cell carcinoma.2009

    • Author(s)
      Ideo A, Hashimoto K, Shimada J, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 29

      Pages: 175-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by naphtha[2, 3-b]furan-4, 9-diones and related compounds in human tumor cell lines: relationship to electronic structure.2009

    • Author(s)
      Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, Motohiashi N, Sakagami H, Yamamoto K, Tanaka A
    • Journal Title

      Anticancer Res 29

      Pages: 455-464

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by benzo[b]cyclohept[e][1, 4]oxazine and 2-aminotropone derivatives.2009

    • Author(s)
      Narita T, Suga A, Kobayashi M, Hashimoto K, Sakagami H, Motohashi N, Kurihara T, Wakabayashi H
    • Journal Title

      Anticancer Res 29

      Pages: 1123-1130

    • NAID

      120005520592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell line2009

    • Author(s)
      Hatano H, Takekawa H, Hashimoto K, Ishihara M, et al., (8名)
    • Journal Title

      Anticancer Research 29

      Pages: 3079-3086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines2009

    • Author(s)
      Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, Motohashi N, Sakagami H, Yamamoto K, Tanaka A.
    • Journal Title

      relationship to electronic structure. Anticancer Res. Jan 29(1)

      Pages: 455-464

    • Data Source
      KAKENHI-PROJECT-20592233
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines : relationship to electronic structure2009

    • Author(s)
      Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, 他4名
    • Journal Title

      Anticancer Res. 29(1)

      Pages: 455-464

    • NAID

      120005520593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592233
  • [Journal Article] Tumor-specific cytotoxic activity of 1, 2, 3, 4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines2009

    • Author(s)
      Hatano H, Takekawa H, Hashimoto K, Ishihara M, Kawase M, Chu Q, Wang QT, Sakagami H
    • Journal Title

      Anticancer Res 29

      Pages: 3079-3086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines.2008

    • Author(s)
      Murayama H, Miyahara K, Wakabayashi H, Kurihara T, Hashimoto K, Amano O, Kikuchi H, Nakamura Y, Kanda Y, Kunii S, Motohashi N, Sakagami H.
    • Journal Title

      Anticancer Res 28

      Pages: 1069-1078

    • NAID

      120005520596

    • Data Source
      KAKENHI-PROJECT-20592233
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by β-cyclodextrin benzaldehyde inclusion compound.2008

    • Author(s)
      Liu Y, Sakagami H, Hashimoto K, Kikuchi H, Amano O, Ishihara M, Kanda Y, Kunii S, Kochi M, Zhang W, Yu G
    • Journal Title

      Anticancer Res 28

      Pages: 229-236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specificic cytotoxicity and type of cell death induced by sodium 5, 6-benzylidene-L-ascorbate.2008

    • Author(s)
      Kishino K, Hashimoto K, Amano O, Kochi M, Sakagami H
    • Journal Title

      Anticancer Res 28

      Pages: 2577-2584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specificity and type of cell death induced by vitamin K2 derivatives and prenylalcohols.2008

    • Author(s)
      Sakagami H, Hashimoto K, Suzuki F, Ishihara M, Kikuchi H, Katayama T, Satoh K
    • Journal Title

      Anticancer Res 28

      Pages: 151-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines.2008

    • Author(s)
      Murayama H, Miyahara K, Kurihara T, Hashimoto K, Amano O, Kikuchi H, Nakamura Y, 他4人
    • Journal Title

      Anticancer Res. 28

      Pages: 1069-1078

    • NAID

      120005520596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592233
  • [Journal Article] Induction of apoptosis by epigallocatechin gallate and autophagy inhibitors in a mouse macrophage-like cell line2008

    • Author(s)
      Hashimoto K, Sakagami H
    • Journal Title

      Anticancer Res 28

      Pages: 1713-1718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines.2008

    • Author(s)
      Murayama H, Miyahara K, Wakabayashi H, Kurihara T, Hashimoto K, Amano O, Kikuchi H, Nakamura Y, Kanda Y, Kunii S, Motohashi N, Sakagami H
    • Journal Title

      Anticancer Res 28

      Pages: 1069-1078

    • NAID

      120005520596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Induction of apoptosis by epigallocatechin gallate and autophagy inhibitors in a mouse macrophage-like cell line.2008

    • Author(s)
      Hashimoto K, Sakagami H
    • Journal Title

      Anticancer Res 28

      Pages: 1713-1718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxic activity and type of cell death induced by 4-trifluoromethylimidazoles in human oral squamous cell carcinoma cell lines.2007

    • Author(s)
      Takekawa F, Nagumo T, Shintani S, Hashimoto K, Kikuchi H, Katayama T, Ishihara M, Amano O, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 27

      Pages: 4065-4070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specificity and type of cell death induced by phenoxazines.2007

    • Author(s)
      Suzuki F, Hashimoto K, Ishihara M, Westman G, Samuelsson K, Kawase M, Motohashi N, Sakagami H
    • Journal Title

      Anticancer Res 27

      Pages: 4233-4238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] タンニンータンパク質複合体のヒト癌細胞株に対する腫瘍選択性と誘導される細胞死のタイプ2010

    • Author(s)
      坂上宏, 岸野香織, 橋本研, 野崎阿季子, 波多野力
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] ヒト口腔癌細胞の細胞死誘導におけるDNaseγの役割2009

    • Author(s)
      橋本研, 坂上宏
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] ベンズアルデヒドによりヒト口腔扁平上皮癌細胞に誘導される細胞死の解析2009

    • Author(s)
      岸野香織, 橋本研, 天野修, 坂上宏
    • Organizer
      第51回歯科基礎医学会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] Induction of non-apoptosis by a, b-unsaturated ketones in OSCC cell lines2008

    • Author(s)
      Sakagami H, Hashimoto K, Ishihara M, Nagasaka H, Kawase M, Dimmock J
    • Organizer
      IADR
    • Place of Presentation
      Toronto
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] 複素環式化合物の腫瘍選択性と誘導される細胞死のタイプ2008

    • Author(s)
      坂上宏, 橋本研, 小林正樹, 鈴木史香, 竹川文弘石原真理子, 天野修, 菊地寛高, 中村幸生, 河瀬雅美, 本橋登
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] ベンズアルデヒド類のヒト口腔扁平上皮癌細胞に対する選択毒性2007

    • Author(s)
      坂上宏, 劉宇, 岸野香織, 小林正樹, 橋本研, 石原真理子
    • Organizer
      第49回歯科基礎医学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19592156
  • 1.  SAKAGAMI Hiroshi (50138484)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 20 results
  • 2.  KAWASE Masami (20112641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  MIMAKI Yoshihiro (90229790)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  YUKIO Nakamura (40207931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  須田 朋代 (60226579)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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