Sekine Masayuki 関根正幸

… Alternative Names

SEKINE Masayuki 関根正幸

関根正幸セキネマサユキ

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Researcher Number	70345502
Other IDs
Affiliation (Current)	2025: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2025: 琉球大学, 医学(系)研究科(研究院), 教授 2023: 琉球大学, 医学(系)研究科(研究院), 教授 2014 – 2022: 新潟大学, 医歯学系, 准教授 2017: 新潟大学, 医歯学総合病院, 助教 2013: 新潟大学, 医歯学系, 講師 2008 – 2011: Niigata University, 医歯学総合病院, 助教 2003 – 2004: 新潟大学, 医歯学総合病院, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator HPV感染 / 中咽頭癌 / 卵巣癌 / 遺伝性腫瘍 / 婦人科腫瘍 / 婦人科腫瘍学 / 子宮頸癌 / 感染予防 / 咽頭 / HPVワクチン … More / 卵巣がん / PARP阻害薬 / BRCA遺伝子 / 遺伝性乳癌卵巣癌 / BRCA / HRD / Ovarian cancer / 脳転移 / 分子生物学 / BRCA1、2 / 家族性卵巣癌 … More Except Principal Investigator cancer / Intratumor heterogeneity / spheroid / cancer genome / intratumor heterogeneity / mutation / translational research / Transcriptome / Endometrioid carcinoma / 類内膜癌関連遺伝子 / ミュラー管由来類内膜腺癌 / トランスレーショナルリサーチ / プロテオーム / 癌 / ゲノム / マイクロアレイ / トランスレーショナルリサーチ / proteome / genome / microarray / Translational research / 上皮間葉移行 / 分子標的治療薬 / 上皮性卵巣癌 / 腫瘍内浸潤リンパ球 / 予後予測 / 上皮性卵巣がん / 遺伝子発現プロファイル / 抗原提供 / EMT / 卵巣がん Less

BRCA遺伝子common mutationの同定から予防医療の個別化に向けてPrincipal Investigator
- Principal Investigator
  
  関根正幸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of the Ryukyus
Study on the process of carcinogenesis by HPV infection comparing pharynx and cervixPrincipal Investigator
- Principal Investigator
  
  関根正幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  University of the Ryukyus
  Niigata University
Efficacy of the human papillomavirus vaccine against HPV infection in the pharynx?Principal Investigator
- Principal Investigator
  
  Sekine Masayuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Niigata University
Genetic analysis of 19 susceptibility genes including BRCA1/2 genes in ovarian cancerPrincipal Investigator
- Principal Investigator
  
  Sekine Masayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
Clarification of molecular biological feature of Mullerian endometrioid adenocarcinoma and establishment of differentiation of its origin
- Principal Investigator
  
  YAMAGUCHI Masayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
Elucidating the mechanism of resistance to chemotherapy in gynecologic cancer based on intratumor heterogeneity
- Principal Investigator
  
  Enomoto Takayuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
Investigation of molecules related in brain metastasis in Hereditary Breast and Ovarian CancerPrincipal Investigator
- Principal Investigator
  
  Sekine Masayuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
Identification of molecular characteristics in serous carcinoma of Mullerian origin
- Principal Investigator
  
  ENOMOTO Takayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
Down regulation of antigen presentation pathway plays an important role in metastasis and progression of advanced stage of epithelial ovarian cancer.
- Principal Investigator
  
  TANAKA Kenichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
家族性乳癌卵巣癌の発症に関与する原因遺伝子の同定Principal Investigator
- Principal Investigator
  
  関根正幸
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University
BRCA1、2の臓器特異性発癌に関する研究-なぜ乳房と卵巣だけが癌化するか-Principal Investigator
- Principal Investigator
  
  関根正幸
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Niigata University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2009 2008 Other

All Journal Article Presentation Book Other

[Book] 産科婦人科疾患　最新の治療2019-20212019
- Author(s)
  関根正幸
- Total Pages
  304
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-16K11133
[Book] 婦人科腫瘍遺伝カウンセリングマニュアル：PARP阻害薬とhomologous recombination deficiency2018
- Author(s)
  関根正幸、榎本隆之
- Total Pages
  130
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-16K11133
[Book] Frontiers in Ovarian Cancer Science: Hereditary Ovarian Cancer2017
- Author(s)
  Masayuki Sekine, Takayuki Enomoto
- Total Pages
  314
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-16K11133
[Book] 産科婦人科疾患　最新の治療　2016-20182016
- Author(s)
  関根正幸、榎本隆之
- Total Pages
  5
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-26670716
[Journal Article] 発がんメカニズムと予防・検診　子宮頸がん予防　HPVワクチンが果たす役割2023
- Author(s)
  工藤梨沙, 黒澤めぐみ, 関根正幸
- Journal Title
  
  産科と婦人科
  
  Volume: 90巻11号 Pages: 1187-1193
- Data Source
  KAKENHI-PROJECT-22K10506
[Journal Article] 子宮頸がんにおけるHPVワクチンの安全性と有効性,今後の課題2023
- Author(s)
  黒澤めぐみ, 関根正幸, 山口真奈子, 工藤梨沙, 榎本隆之
- Journal Title
  
  ENTONI
  
  Volume: 281号 Pages: 1-11
- Data Source
  KAKENHI-PROJECT-22K10506
[Journal Article] HPVワクチンの有効性　2価・4価ワクチンを使用した日本・海外における臨床データ2022
- Author(s)
  黒澤めぐみ, 山口真奈子, 工藤梨沙, 関根正幸, 榎本隆之
- Journal Title
  
  臨床婦人科産科
  
  Volume: 76巻8号 Pages: 754-761
- Data Source
  KAKENHI-PROJECT-22K10506
[Journal Article] 日本の動向と今後の課題　HPVワクチン有効性のエビデンス　新潟スタディ2022
- Author(s)
  工藤梨沙, 関根正幸, 榎本隆之
- Journal Title
  
  産科と婦人科
  
  Volume: 89巻6号 Pages: 623-627
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] HPVワクチン積極的勧奨再開へ向けて2022
- Author(s)
  工藤梨沙, 関根正幸, 山口真奈子, 黒澤めぐみ, 安達聡介, 榎本隆之
- Journal Title
  
  新潟県医師会報
  
  Volume: 864号 Pages: 10-15
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] Long-Term Effects of Human Papillomavirus Vaccination in Clinical Trials and Real-World Data: A Systematic Review2022
- Author(s)
  Kurosawa M, Sekine M *, Yamaguchi M, Kudo R, Hanley SJB, Hara M, Adachi S, Ueda Y, Miyagi E, Ikeda S, Yagi A, Enomoto T.
- Journal Title
  
  Vaccines
  
  Volume: Feb 8;10(2) Issue: 2 Pages: 256-256
- DOI
  10.3390/vaccines10020256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10640, KAKENHI-PROJECT-20K09638, KAKENHI-PROJECT-21K11679
[Journal Article] HPVワクチンの有効性　2価・4価ワクチンを使用した日本・海外における臨床データ2022
- Author(s)
  黒澤めぐみ, 山口真奈子, 工藤梨沙, 関根正幸, 榎本隆之
- Journal Title
  
  臨床婦人科産科
  
  Volume: 76巻8号 Pages: 754-761
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] Long-term effectiveness of HPV vaccination against HPV infection in young Japanese women: Real-world data2022
- Author(s)
  Kurosawa M, Sekine M *, Yamaguchi M, Kudo R, Hanley SJB, Hara M, Adachi S, Ueda Y, Miyagi E, Ikeda S, Yagi A, Enomoto T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 113(4) Issue: 4 Pages: 1435-1440
- DOI
  10.1111/cas.15282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10640, KAKENHI-PROJECT-20K09638, KAKENHI-PROJECT-21K11679
[Journal Article] 日本の動向と今後の課題　HPVワクチン有効性のエビデンス　新潟スタディ2022
- Author(s)
  工藤梨沙, 関根正幸, 榎本隆之
- Journal Title
  
  産科と婦人科
  
  Volume: 89巻6号 Pages: 623-627
- Data Source
  KAKENHI-PROJECT-22K10506
[Journal Article] トピックス　HPVワクチンの最新の話題2022
- Author(s)
  工藤梨沙, 関根正幸, 榎本隆之
- Journal Title
  
  ペリネイタルケア
  
  Volume: 41巻2号 Pages: 173-177
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] 【ワクチンの安全性と社会学-HPVワクチンの接種はなぜ広まらないのか?-】HPVワクチンについて　HPVワクチンの有効性　最近の動向2021
- Author(s)
  関根正幸, 工藤梨沙, 山口真奈子, 安達聡介, 黒澤めぐみ, 榎本隆之
- Journal Title
  
  産婦人科の実際
  
  Volume: 70巻3号 Pages: 285-291
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] Suspension of proactive recommendations for HPV vaccination has led to a significant increase in HPV infection rates in young Japanese women: real-world data2021
- Author(s)
  Sekine M, Yamaguchi M, Kudo R, Hanley SJB, Ueda Y, Adachi S, Kurosawa M, Miyagi E, Hara M, Enomoto T.
- Journal Title
  
  Lancet Reg Health West Pac.
  
  Volume: Oct 21;16 Pages: 100300-100300
- DOI
  10.1016/j.lanwpc.2021.100300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10640, KAKENHI-PROJECT-20K09638
[Journal Article] Internet Survey of Awareness and Behavior Related to HPV Vaccination in Japan.2021
- Author(s)
  Kudo R, Sekine M, Yamaguchi M, Hara M, Hanley SJB, Ueda Y, Yagi A, Adachi S, Kurosawa M, Miyagi E, Enomoto T.
- Journal Title
  
  Vaccines
  
  Volume: 25;9(2) Issue: 2 Pages: 87-87
- DOI
  10.3390/vaccines9020087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] 特集ワクチンの安全性と社会学-HPVワクチンの接種はなぜ広まらないのか?- Ⅱ.HPVワクチンについて 1.HPVワクチンの有効性2021
- Author(s)
  関根正幸, 工藤梨沙, 山口真奈子, 安達聡介, 黒澤めぐみ, 榎本隆之
- Journal Title
  
  産婦人科の実際
  
  Volume: 70 Issue: 3 Pages: 285-291
- DOI
  10.18888/sp.0000001658
- ISSN
  0558-4728
- Year and Date
  2021-03-01
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] Risk factors for HPV infection and high-grade cervical disease in sexually active Japanese women.2021
- Author(s)
  Yamaguchi M, Sekine M, Hanley SJB, Kudo R, Hara M, Adachi S, Ueda Y, Miyagi E, Enomoto T.
- Journal Title
  
  Sci Rep.
  
  Volume: 3;11(1) Issue: 1 Pages: 2898-2898
- DOI
  10.1038/s41598-021-82354-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10640, KAKENHI-PROJECT-20K09638
[Journal Article] Japan's Ongoing Crisis on HPV Vaccination.2020
- Author(s)
  Sekine M, Kudo R, Yamaguchi M, Hanley SJB, Hara M, Adachi S, Ueda Y, Miyagi E, Ikeda S, Yagi A, Enomoto T.
- Journal Title
  
  Vaccines
  
  Volume: 6;8(3) Issue: 3 Pages: 362-362
- DOI
  10.3390/vaccines8030362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] 【子宮頸がん予防-日本はどうする?-】HPVワクチン接種プログラムのインパクト-日本の現状と課題-2020
- Author(s)
  工藤梨沙、関根正幸
- Journal Title
  
  産婦人科の実際
  
  Volume: 69巻3号 Pages: 257-262
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] Epidemiologic Profile of Type-Specific Human Papillomavirus Infection after Initiation of HPV Vaccination.2020
- Author(s)
  Sekine M, Yamaguchi M, Kudo R, J B Hanley S, Hara M, Adachi S, Ueda Y, Miyagi E, Ikeda S, Yagi A, Enomoto T.
- Journal Title
  
  Vaccines
  
  Volume: 29;8(3) Issue: 3 Pages: 425-425
- DOI
  10.3390/vaccines8030425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] 婦人科腫瘍の新たな治療戦略　卵巣がんの新たな治療戦略 ―PARP阻害薬―2019
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  Pharma Medica
  
  Volume: 2 Pages: 19-32
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] 【ご存じですか？産婦人科領域で話題の薬物療法】卵巣がんに対するPARP阻害薬-オラパリブを中心に-2019
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  産婦人科の実際
  
  Volume: 68(4) Pages: 391-396
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] 【卵巣がん征圧へのマイルストーン】卵巣がん二次化学療法に関する臨床試験のこれから -―分子標的薬を中心に―2019
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  産婦人科の実際
  
  Volume: 68(3) Pages: 257-265
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] 【子宮頸がんとHPVワクチンを考える】HPVワクチンの有効性2019
- Author(s)
  関根正幸、工藤梨沙、山口真奈子、安達聡介、榎本隆之
- Journal Title
  
  外来小児科
  
  Volume: 22巻1号 Pages: 55-60
- Data Source
  KAKENHI-PROJECT-19K10640
[Journal Article] Clinical background and outcomes of risk-reducing salpingo-oophorectomy for hereditary breast and ovarian cancers in Japan2019
- Author(s)
  Nomura Hidetaka、Sekine Masayuki、Yokoyama Shiro、Arai Masami、Enomoto Takayuki、Takeshima Nobuhiro、Nakamura Seigo
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 24 Issue: 9 Pages: 1-6
- DOI
  10.1007/s10147-019-01456-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] Malignancy during pregnancy in Japan: an exceptional opportunity for early diagnosis.2018
- Author(s)
  Sekine M, Kobayashi Y, Tabata T, Sudo T, Nishimura R, Matsuo K, Grubbs BH, Enomoto T, Ikeda T.
- Journal Title
  
  BMC Pregnancy Childbirth.
  
  Volume: 18(1) Issue: 1 Pages: 50-50
- DOI
  10.1186/s12884-018-1678-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11133, KAKENHI-PROJECT-17H04336, KAKENHI-PROJECT-15K10707
[Journal Article] 卵巣がん卵巣癌の治療 PARP阻害薬2018
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  日本臨床
  
  Volume: 76 Pages: 640-645
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] 【最新!婦人科がん薬物療法-化学療法薬から分子標的薬・免疫療法薬まで】卵巣がん PARP阻害薬の現況と展望2017
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  臨床婦人科産科
  
  Volume: 71巻10号 Pages: 924-934
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] わが国の上皮性卵巣癌における遺伝性評価の対象と方法2017
- Author(s)
  関根正幸
- Journal Title
  
  日本医事新報
  
  Volume: 4886 Pages: 62-62
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] 遺伝性乳癌卵巣癌2016
- Author(s)
  関根正幸
- Journal Title
  
  産婦人科の実際
  
  Volume: 65巻 Pages: 661-665
- Data Source
  KAKENHI-PROJECT-16K11133
[Journal Article] Mothers' attitudes in Japan regarding cervical cancer screening correlates with intention to recommend cervical cancer screening for daughters.2016
- Author(s)
  Egawa-Takata T, Ueda Y, Tanaka Y, Morimoto A, Kubota S, Yagi A, Terai Y, Ohmichi M, Ichimura T, Sumi T, Murata H, Okada H, Nakai H, Mandai M, Yoshino K, Kimura T, Saito J, Kudo R, Sekine M, Enomoto T, Horikoshi Y, Takagi T, Shimura K.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 21 Issue: 5 Pages: 962-968
- DOI
  10.1007/s10147-016-0970-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15598, KAKENHI-PROJECT-16K11137
[Journal Article] 遺伝性乳がん卵巣がん症候群(HBOC)と遺伝カウンセリング HBOCにおける卵巣がんの特異性と対応2015
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  日本遺伝カウンセリング学会誌
  
  Volume: 36 Pages: 33-37
- Data Source
  KAKENHI-PROJECT-26670716
[Journal Article] HBOCにおける卵巣がんの特異性と対応2015
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  日本遺伝カウンセリング学会誌
  
  Volume: 36 Pages: 33-37
- Data Source
  KAKENHI-PROJECT-26670716
[Journal Article] Japan’s failure to vaccinate girls against human papillomavirus2015
- Author(s)
  Ueda , Y., Enomoto, T., Sekine ,M., Egawa-Takata, T., Morimoto, A., Kimura ,T.
- Journal Title
  
  American Journal of Obstetrics and Gynecology
  
  Volume: 212（3） Issue: 3 Pages: 405-406
- DOI
  10.1016/j.ajog.2014.11.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293338
[Journal Article] わが国のBRCA変異を伴う卵巣癌の現況2015
- Author(s)
  関根正幸、榎本隆之
- Journal Title
  
  産科と婦人科
  
  Volume: 82 Pages: 605-610
- Data Source
  KAKENHI-PROJECT-26670716
[Journal Article] Outcomes and Prognostic Factors for Adenocarcinoma/Adenosquamous Carcinomas Treated with Radical Hysterectomy and Adjuvant Therapy.2014
- Author(s)
  Yamaguchi,M., Yamagishi,Y., Nishikawa,N., Sekine,M., Serikawa,T., Kashima,K., Enomoto,T
- Journal Title
  
  Open J Obstet Gynecology
  
  Volume: 4 Issue: 14 Pages: 909-915
- DOI
  10.4236/ojog.2014.414128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293338
[Journal Article] Preoperative Ultrasound- Guided Needle Biopsy of 63 Uterine Tumors Having High Signal Intensity Upon T2- Weighted Magnetic Resonance Imaging2014
- Author(s)
  Tamura,R., Kashima,K., Asatani,M., Nishino,K., Nishikawa,N., Sekine,M., Serikawa,T., and Enomoto,T.
- Journal Title
  
  Int J of Gynecological Cancer
  
  Volume: 24(6) Issue: 6 Pages: 1042-1047
- DOI
  10.1097/igc.0000000000000189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293338
[Journal Article] BRCAl, BRCA2と卵巣癌2008
- Author(s)
  関根正幸
- Journal Title
  
  腫瘍内科 2(5)
  
  Pages: 426-432
- Data Source
  KAKENHI-PROJECT-20591939
[Presentation] HPV関連腫瘍を俯瞰する:予防・診断・治療　子宮頸がん予防におけるHPVワクチン有効性の実証と今後の課題2023
- Author(s)
  関根正幸
- Organizer
  第61回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K10506
[Presentation] 子宮頸がん予防に関する最新情報2023
- Author(s)
  関根正幸
- Organizer
  日本婦人科腫瘍学会第10回研修会
- Invited
- Data Source
  KAKENHI-PROJECT-22K10506
[Presentation] HPVワクチン積極的勧奨再開までの道のりと今後の課題2023
- Author(s)
  関根正幸
- Organizer
  第64回日本臨床細胞学会総会（春期大会）
- Invited
- Data Source
  KAKENHI-PROJECT-22K10506
[Presentation] HPV関連癌(子宮頸癌および中咽頭癌)における診療の現状と予防への展望　子宮頸癌予防におけるHPVワクチン有効性の実証2021
- Author(s)
  関根正幸, 黒澤めぐみ, 山口真奈子, 工藤梨沙, 安達聡介, 榎本隆之
- Organizer
  日本癌治療学会学術講演会　シンポジウム
- Data Source
  KAKENHI-PROJECT-19K10640
[Presentation] 子宮頸癌征圧に向けて～予防と初期病変管理の最前線～　子宮頸癌予防におけるHPVワクチン有効性の実証2021
- Author(s)
  関根正幸
- Organizer
  日本産科婦人科学会学術講演会　シンポジウム
- Data Source
  KAKENHI-PROJECT-19K10640
[Presentation] 日本人若年女性におけるHPV9価ワクチン導入効果の予測2020
- Author(s)
  山口真奈子, 関根正幸, 工藤梨沙, 安達聡介, 榎本隆之
- Organizer
  日本婦人科腫瘍学会
- Data Source
  KAKENHI-PROJECT-19K10640
[Presentation] HPVワクチンの長期的なHPV16型、18型感染予防効果2020
- Author(s)
  黒澤めぐみ, 関根正幸, 山口真奈子, 工藤梨沙, 安達聡介, 八木麻未, 池田さやか, 上田豊, 宮城悦子, 原めぐみ, ハンリー・シャロン , 榎本隆之
- Organizer
  日本癌治療学会
- Data Source
  KAKENHI-PROJECT-19K10640
[Presentation] 婦人科におけるHBOC診療の方向性2018
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 仙台
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 測定可能病変有無別のBRCA変異陽性白金製剤感受性再発卵巣癌における抗腫瘍効果とolaparibの有効性：SOLO22018
- Author(s)
  関根正幸
- Organizer
  第70回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 遺伝性卵巣癌の診療とサーベイランス2018
- Author(s)
  関根正幸
- Organizer
  第70回日本産科婦人科学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] PARP阻害薬とBRCA遺伝子検査の方向性2018
- Author(s)
  関根正幸
- Organizer
  第24回日本家族性腫瘍学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 遺伝性腫瘍－総論－2018
- Author(s)
  関根正幸
- Organizer
  第71回日本産科婦人科学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 乳癌卵巣癌と遺伝のはなし2018
- Author(s)
  関根正幸
- Organizer
  第59回日本母性衛生学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の方向性2018
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 栃木
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] PARP 阻害薬と相同組換え修復異常（homologous recombination deficiency: HRD）2018
- Author(s)
  関根正幸
- Organizer
  第60回日本婦人科腫瘍学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌の治療2017
- Author(s)
  関根正幸
- Organizer
  第３回HBOC教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌のサーベイランス2017
- Author(s)
  関根正幸
- Organizer
  第３回HBOC教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌のサーベイランス2017
- Author(s)
  関根正幸
- Organizer
  第２回HBOC教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 卵巣がんにおけるBRCA遺伝子検査とPARP阻害薬の展望2017
- Author(s)
  関根正幸
- Organizer
  第５回日本HBOCコンソーシアム学術総会
- Place of Presentation
  札幌医科大学（北海道札幌市）
- Year and Date
  2017-01-21
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 「遺伝性卵巣がんは何が違うのか？－婦人科医が開ける遺伝の扉－」2017
- Author(s)
  関根正幸
- Organizer
  第59回日本婦人科腫瘍学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の方向性2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 兵庫
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の方向性2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 柏
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の方向性2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 城西
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌の治療2017
- Author(s)
  関根正幸
- Organizer
  第２回HBOC教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科における遺伝性卵巣がんの診療－BRCA検査の普及に向けて－2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 山形
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌の治療2017
- Author(s)
  関根正幸
- Organizer
  第１回HBOC教育セミナー
- Place of Presentation
  聖路加国際大学（東京都中央区）
- Year and Date
  2017-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌のサーベイランス2017
- Author(s)
  関根正幸
- Organizer
  第１回HBOC教育セミナー
- Place of Presentation
  聖路加国際大学（東京都中央区）
- Year and Date
  2017-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の方向性2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 沖縄
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 「BRCA遺伝子検査とPARP阻害薬の展望」2017
- Author(s)
  関根正幸
- Organizer
  第3回日本産科婦人科遺伝診療学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の現状と今後の課題2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 横浜
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] HBOC卵巣癌のサーベイランス2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 新潟
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 婦人科におけるHBOC診療の方向性2017
- Author(s)
  関根正幸
- Organizer
  Scientific Exchange Meeting 松本
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 「遺伝性乳がん・卵巣がん症候群（HBOC）と医療倫理」2016
- Author(s)
  関根正幸
- Organizer
  大阪産婦人科医会第 14 回倫理講習会・臨床セミナー
- Place of Presentation
  ハートンホテル心斎橋、大阪府大阪市
- Year and Date
  2016-04-16
- Invited
- Data Source
  KAKENHI-PROJECT-26670716
[Presentation] 「遺伝性乳癌卵巣癌（HBOC）の基礎と臨床－遺伝子診断の普及に向けて－」2016
- Author(s)
  関根正幸
- Organizer
  北日本産科婦人科学会総会・学術講演会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-16K11133
[Presentation] 「遺伝性乳がん卵巣がん(HBOC: Hereditary Breast and Ovarian Cancer)の基礎と臨床」2015
- Author(s)
  関根正幸
- Organizer
  第708回新潟医学会
- Place of Presentation
  有壬記念館、新潟県新潟市
- Year and Date
  2015-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-26670716
[Presentation] 遺伝性卵巣癌のUp to date2015
- Author(s)
  関根正幸
- Organizer
  第 57 回日本婦人科腫瘍学会学術講演会
- Place of Presentation
  アイーナいわて、岩手県盛岡市
- Year and Date
  2015-08-07
- Invited
- Data Source
  KAKENHI-PROJECT-26670716
[Presentation] 『遺伝性乳癌・卵巣癌（HBOC）に関する最近のトピックス』2015
- Author(s)
  関根正幸
- Organizer
  福井県産婦人科医師連合　夏期臨床研修会
- Place of Presentation
  ユアーズホテルフクイ、福井県福井市
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-26670716
[Presentation] 上皮性卵巣癌における脳転移とBRCAl遺伝子異常の関連2009
- Author(s)
  関根正幸
- Organizer
  関越DIF研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591939
[Presentation] 遺伝性卵巣がんの臨床
- Author(s)
  関根正幸、榎本隆之、田中憲一
- Organizer
  日本婦人科腫瘍学会学術集会
- Place of Presentation
  宇都宮市
- Year and Date
  2014-07-17 – 2014-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-26670716
[Presentation] ＨＢＯＣにおける卵巣がんの特異性と対応
- Author(s)
  関根正幸、榎本隆之
- Organizer
  日本遺伝カウンセリング学会学術集会
- Place of Presentation
  東大阪市
- Year and Date
  2014-06-28 – 2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670716
[Presentation] 卵巣がんの早期発見が可能であったBRCA1キャリアの一例
- Author(s)
  関根正幸, 吉原弘祐, 芹川武大, 加嶋克則, 榎本隆之, 田中憲一
- Organizer
  日本癌治療学会
- Place of Presentation
  横浜市
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26670716
[]

1. ENOMOTO Takayuki (90283754)

# of Collaborated Projects: 6 results

# of Collaborated Products: 36 results
2. YOSHIHARA Kousuke (40547535)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 加嶋克則 (50345500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TANAKA Kenichi (10126427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAHATA Tetsuro (90293232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. INOUE Iturou (00192500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKA Tetuji (30303936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHINO Kiyoshi (90362730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UEDA Yutaka (10346215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. ADACHI Sousuke (50613147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAGUCHI Masayuki (20529771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 芹川武大 (30361918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 吉田邦彦 (20648589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 石黒竜也 (80625690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 植木雄志 (10727564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 工藤梨沙 (30752787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Sekine Masayuki 関根 正幸

SEKINE Masayuki 関根 正幸

関根 正幸 セキネ マサユキ

Research Projects

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Co-Researchers

BRCA遺伝子common mutationの同定から予防医療の個別化に向けてPrincipal Investigator

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Study on the process of carcinogenesis by HPV infection comparing pharynx and cervixPrincipal Investigator

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Efficacy of the human papillomavirus vaccine against HPV infection in the pharynx?Principal Investigator

Principal Investigator

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Review Section

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Genetic analysis of 19 susceptibility genes including BRCA1/2 genes in ovarian cancerPrincipal Investigator

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Clarification of molecular biological feature of Mullerian endometrioid adenocarcinoma and establishment of differentiation of its origin

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Elucidating the mechanism of resistance to chemotherapy in gynecologic cancer based on intratumor heterogeneity

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Investigation of molecules related in brain metastasis in Hereditary Breast and Ovarian CancerPrincipal Investigator

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Identification of molecular characteristics in serous carcinoma of Mullerian origin

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Down regulation of antigen presentation pathway plays an important role in metastasis and progression of advanced stage of epithelial ovarian cancer.

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家族性乳癌卵巣癌の発症に関与する原因遺伝子の同定Principal Investigator

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Research Institution

BRCA1、2の臓器特異性発癌に関する研究-なぜ乳房と卵巣だけが癌化するか-Principal Investigator

Principal Investigator

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[Book] 産科婦人科疾患 最新の治療2019-20212019

Author(s)

Total Pages

Publisher

Data Source

[Book] 婦人科腫瘍遺伝カウンセリングマニュアル：PARP阻害薬とhomologous recombination deficiency2018

Author(s)

Total Pages

Sekine Masayuki 関根正幸

SEKINE Masayuki 関根正幸

関根正幸セキネマサユキ

[Book] 産科婦人科疾患　最新の治療2019-20212019

[Book] 産科婦人科疾患　最新の治療　2016-20182016

[Journal Article] 発がんメカニズムと予防・検診　子宮頸がん予防　HPVワクチンが果たす役割2023

[Journal Article] HPVワクチンの有効性　2価・4価ワクチンを使用した日本・海外における臨床データ2022

[Journal Article] 日本の動向と今後の課題　HPVワクチン有効性のエビデンス　新潟スタディ2022

[Journal Article] HPVワクチンの有効性　2価・4価ワクチンを使用した日本・海外における臨床データ2022

[Journal Article] 日本の動向と今後の課題　HPVワクチン有効性のエビデンス　新潟スタディ2022

[Journal Article] トピックス　HPVワクチンの最新の話題2022

[Journal Article] 【ワクチンの安全性と社会学-HPVワクチンの接種はなぜ広まらないのか?-】HPVワクチンについて　HPVワクチンの有効性　最近の動向2021

[Journal Article] 特集ワクチンの安全性と社会学-HPVワクチンの接種はなぜ広まらないのか?- Ⅱ.HPVワクチンについて 1.HPVワクチンの有効性2021