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KUWATA TAKEO  桑田 岳夫

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Kuwata Takeo  桑田 岳夫

KUWATA Takeo  桑田 岳夫

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Researcher Number 70346063
Other IDs
Affiliation (Current) 2020: 熊本大学, ヒトレトロウイルス学共同研究センター, 特定事業教員
Affiliation (based on the past Project Information) *help 2020: 熊本大学, ヒトレトロウイルス学共同研究センター, 特定事業教員
2018 – 2019: 熊本大学, エイズ学研究センター, 特定事業教員
2017: 熊本大学, エイズ学研究センター, 特任講師
2014 – 2016: 熊本大学, エイズ学研究センター, 助教
2011 – 2012: 熊本大学, エイズ学研究センター, 助教
2010: 熊本大学, 大学院・先導機構, 特任助教
Review Section/Research Field
Principal Investigator
Laboratory animal science / Laboratory animal science / Basic Section 42040:Laboratory animal science-related
Except Principal Investigator
Infectious disease medicine / Basic Section 54030:Infectious disease medicine-related
Keywords
Principal Investigator
SIV / HIV / アカゲザル / エイズ / 中和抗体 / モノクローナル抗体 / ウイルス / 感染症 / 免疫学 / antibody / vaccine / ワクチン / 抗体 … More
Except Principal Investigator
… More 感染症治療学 / 感染症防御学 / ウイルス / 内科 / 感染症 / HIV/AIDS / 中和抗体 Less
  • Research Projects

    (5 results)
  • Research Products

    (59 results)
  • Co-Researchers

    (11 People)
  •  Identification of broadly neutralizing antibodies to HIV-1 and its correlates with host genetic factorsOngoing

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Kumamoto University
  •  SIV感染サルを用いた強力な中和抗体を誘導するメカニズムの解析Principal InvestigatorOngoing

    • Principal Investigator
      桑田 岳夫
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kumamoto University
  •  Research toward elimination of HIV persistent infected cells remaining under antiretroviral therapy (ART)

    • Principal Investigator
      Matsushita Shuzo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kumamoto University
  •  Development of antibody-inducing vaccine models by analysis of B404 which neutralizes various SIV strainsPrincipal Investigator

    • Principal Investigator
      Kuwata Takeo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  Analysis of autoantibodies induced during progression to AIDSPrincipal Investigator

    • Principal Investigator
      KUWATA Takeo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University

All 2019 2018 2017 2016 2015 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

  • [Journal Article] The role of conventional antibodies targeting the CD4 binding site and CD4-induced epitopes in the control of HIV-1 CRF01_AE viruses2019

    • Author(s)
      Thida W, Kuwata T, Maeda Y, Yamashiro T, Tran GV, Nguyen KV, Takiguchi M, Gatanaga H, Tanaka K, Matsushita S
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 508 Pages: 46-51

    • DOI

      10.1016/j.bbrc.2018.11.063

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09938, KAKENHI-PROJECT-18K06032, KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-18H02854
  • [Journal Article] Total HIV-1 DNA Dynamics and Influencing Factors in Long-Term ART-Treated Japanese Adults: A Retrospective Longitudinal Analysis2018

    • Author(s)
      Stanoeva KR, König A, Fukuda A, Kawanami Y, Kuwata T, Satou Y, Matsushita S.
    • Journal Title

      Journal of Acquired Immune Deficiency Syndromes

      Volume: - Pages: 239-247

    • DOI

      10.1097/qai.0000000000001662

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09016, KAKENHI-PROJECT-15H04870, KAKENHI-PROJECT-18K06032, KAKENHI-PROJECT-18H02854
  • [Journal Article] Unique binding modes for the broad neutralizing activity of single-chain variable fragments (scFv) targeting CD4-induced epitopes2017

    • Author(s)
      T1.Tanaka, K., Kuwata, T., Alam, M., Kaplan., G, Takahama, S., Valdez, K.P.R., Roitburd-Berman, A., Gershoni. J.M., Matsushita, S.
    • Journal Title

      Retrovirology

      Volume: 14 Pages: 44-59

    • DOI

      10.1186/s12977-017-0369-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Journal Article] Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors2016

    • Author(s)
      Alam, M., Kuwata, T., Shimura, K., Yokoyama, M., Ramirez Valdez, K. P., Tanaka, K., Maruta, Y., Oishi, S., Fujii, N., Sato, H., Matsuoka M. and Matsushita S.
    • Journal Title

      Retrovirology

      Volume: 13 Pages: 70-70

    • DOI

      10.1186/s12977-016-0304-7

    • NAID

      120005973385

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430091, KAKENHI-PROJECT-16K08824, KAKENHI-PROJECT-15H04654, KAKENHI-PROJECT-15H04870
  • [Journal Article] Incompatible natures of HIV-1 envelope in resistance to the CCR5 antagonist cenicriviroc and neutralizing antibodies.2016

    • Author(s)
      Kuwata T, Enomoto I, Baba M, Matsushita S
    • Journal Title

      Antimicrob Agents Chemother.

      Volume: 60 Pages: 437-450

    • DOI

      10.1128/aac.02285-15

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26430091, KAKENHI-PROJECT-15H04870
  • [Journal Article] Cross-Neutralization Activity of Single-Chain Variable Fragment (scFv) Derived from Anti-V3 Monoclonal Antibodies Mediated by Post-Attachment Binding2016

    • Author(s)
      Maruta, Y., Kuwata, T., Tanaka, K., Alam, M., Valdez, K. P., Egami, Y., Yoshiaki Suwa, Y., Morioka, H. and Matsushita, S.
    • Journal Title

      Jpn J Infect Dis

      Volume: 69 Issue: 5 Pages: 395-404

    • DOI

      10.7883/yoken.jjid.2015.667

      10.7883/yoken.JJID.2015.667

    • NAID

      130005416280

    • ISSN
      1344-6304, 1884-2836
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430091, KAKENHI-PROJECT-15H04870
  • [Journal Article] Immunoglobulin VH gene diversity and somatic hypermutation during SIV infection of rhesus macaques2015

    • Author(s)
      Guo K, Halemano K, Schmitt K, Katuwal M, Wang Y, Harper MS, Heilman KJ, Kuwata T, Stephens EB, Santiago ML
    • Journal Title

      Immunogenetics

      Volume: 67 Pages: 355-370

    • DOI

      10.1007/s00251-015-0844-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Journal Article] Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains2015

    • Author(s)
      Ramirez, K.P., Kuwata, T., Maruta, Y, Tanaka K., Muntasir, A., Yoshimura, K., Matsushita, S.
    • Journal Title

      Virology

      Volume: 475 Pages: 187-203

    • DOI

      10.1016/j.virol.2014.11.011

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591484, KAKENHI-PROJECT-24591485, KAKENHI-PROJECT-26430091
  • [Journal Article] Conformational epitope consisting of the V3 and V4 loops as a target for potent and broad neutralization of simian immunodeficiency viruses2013

    • Author(s)
      Kuwata T
    • Journal Title

      Journal of Virology

      Volume: in press Pages: 5424-5436

    • DOI

      10.1128/jvi.00201-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500387, KAKENHI-PROJECT-24591484, KAKENHI-PROJECT-24591485, KAKENHI-PUBLICLY-25115519
  • [Journal Article] Conformational epitope consisting of theV3 and V4 loops as a target for potent andbroad neutralization of simianimmunodeficiency viruses2013

    • Author(s)
      Kuwata T, Takaki K, Yoshimura K,Enomoto I, Wu F, Ourmanov I, Hirsch VM,Yokoyama M, Sato H, Matsushita S
    • Journal Title

      J Virol

      Volume: 87(10) Pages: 5424-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Journal Article] Isolation of Potent Neutralizing Monoclonal Antibodies from an SIV-Infected Rhesus Macaque by Phage Display2011

    • Author(s)
      Kuwata, T.
    • Journal Title

      AIDS RESEARCH AND HUMAN RETROVIRUSES

      Volume: 27 Pages: 487-500

    • DOI

      10.1089/aid.2010.0191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300152, KAKENHI-PROJECT-22500387
  • [Journal Article] Isolation of potentneutralizing monoclonal antibodies froman SIV-Infected rhesus macaque by phagedisplay2011

    • Author(s)
      Kuwata T, Katsumata Y, Takaki K, MiuraT, Igarashi T
    • Journal Title

      AIDS Res Hum Retroviruses

      Volume: 27(5) Pages: 487-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Journal Article] Isolation of Potent Neutralizing Monoclonal Antibodies from an SIV-Infected Rhesus Macaque by Phage Display2010

    • Author(s)
      桑田岳夫
    • Journal Title

      AIDS RESEARCH AND HUMAN RETROVIRUSES

      Volume: Vol 26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Patent] 抗HIV抗体の製造方法2018

    • Inventor(s)
      松下修三; 桑田岳夫; 清水 衛; 冨田正浩; 道下眞弘
    • Industrial Property Rights Holder
      松下修三; 桑田岳夫; 清水 衛; 冨田正浩; 道下眞弘
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-203114
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-18K06032
  • [Presentation] 抗HIV治療薬ドルテグラビル、マラビロクを含むcART中に出現した耐性ウイルスの解析2018

    • Author(s)
      桑田岳夫、Kaung Htet Lin、蜂谷敦子、Win Thida、中田浩智、岩谷靖雅、吉村和久、松下修三
    • Organizer
      第28回抗ウイルス療法学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-18K06032
  • [Presentation] Role of Conventional Antibodies in Control of HIV-1 CRF01_AE viruses2018

    • Author(s)
      Thida W, Kuwata T, Maeda Y, Tran G V, Nguyen K V, Takiguchi M, Gatanaga H and Matsushita S
    • Organizer
      HIV Research for Prevention 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06032
  • [Presentation] Analysis of the envelope gene in the patient treated with maraviroc2018

    • Author(s)
      Lin K H, Kuwata T, Thida W, Shimizu M and Matsushita S
    • Organizer
      第32回日本エイズ学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-18K06032
  • [Presentation] 抗イディオタイプ抗体による抗V3中和単クローン抗体産生B細胞単離方法の検討2018

    • Author(s)
      郭悠、桑田岳夫、田中和樹、Biswas Shashwata、Zahid MD Hassan、松下修三
    • Organizer
      第32回日本エイズ学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-18K06032
  • [Presentation] Synergistic inhibition by single chain fragment variables and fusion inhibitors in both cell-free and cell-associated HIV-1 infections2018

    • Author(s)
      Mamun M A, Maruta Y, Tanaka K, Alam M, Thida W, Takahama S, Kuwata T and Matsushita S
    • Organizer
      第32回日本エイズ学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-18K06032
  • [Presentation] Evaluation of Binding affinity and Neutralization Potency and coverage of anti-V3 scFv’sagainst HIV-1 subtype-B viruses.2017

    • Author(s)
      Alam Mohammad, 田中和樹, Muntasir Alam, Win Thida, 桑田岳夫, 松下修三.
    • Organizer
      第31回日本エイズ学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Evaluation of Binding affinity and kinetics, Neutralization Potency and Coverage of anti-V3 scFv’s against HIV-1 Subtype-B viruses in vitro.2017

    • Author(s)
      Mamun M., Maruta Y., Tanaka K., Muntasir A., Thida, W., Kuwata T., Matsushita S.
    • Organizer
      18th Kumamoto AIDS seminar.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Single cell sorting による抗 V3 中和 単クローン抗体に対する抗イディオタイプ.2017

    • Author(s)
      郭 悠, 桑田岳夫, 田中和樹, Alam Mohammad Mamun, 高濱正吉, Hassan MD Zahid, 松下修三.
    • Organizer
      第31回日本エイズ学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Neutralization sensitivities of clade B and CRF01_AE viruses of HIV-1 isolated from patients with recent diagnosis in Japan.2017

    • Author(s)
      Thida, W., Kuwata T., Muntasir A., Tanaka K., Mamun M., Shimizu, M., Kawanami, Y., Matsushita S.
    • Organizer
      18th Kumamoto AIDS seminar
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Total HIV DNA levels dynamics upon ART initiation2016

    • Author(s)
      Stanoeva KR., Konig A., Fukuda A., Kawanami Y., Kuwata T., Satou Y., Matsushita S.
    • Organizer
      2nd Kumamoto IRCMS International Symposium.17th Kumamoto AIDS seminar
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] PM1/CCR5 cells transduced with T312 Intrabody have survival advantage, if challenged with SF162 HIV-1 strain2016

    • Author(s)
      Alves G, Kuwata T, Tanaka Y, Matsushita S
    • Organizer
      17th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本
    • Year and Date
      2016-10-31
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Induction of antibodies, which belonged to the same class as broadly neutralizing antibody B404, in macaques infected with SIVsmH635FC2016

    • Author(s)
      Kuwata T, Sano M, Matsuoka S, Shimizu M, Miura T, Seki Y, Akari H, Matano T and Matsushita S
    • Organizer
      17th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本
    • Year and Date
      2016-10-31
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] HIV proviral DNA quantification in a cohort of Japanese patients on long-term ART2016

    • Author(s)
      Stanoeva K, Konig A, Fukuda A, Kawanami Y, Kuwata T, Satou Y, Matsushita S
    • Organizer
      2016 Towards an HIV Cure Symposium
    • Place of Presentation
      Durban, South Africa
    • Year and Date
      2016-07-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Construction, purification and analysis of neutralization potency of anti-V3 scFv’s against HIV-1 strains in vitro2016

    • Author(s)
      Mamun M, Maruta Y, Tanaka K, Alam M, Thida W, Kuwata T and Matsushita S
    • Organizer
      17th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本
    • Year and Date
      2016-10-31
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Post-attachment Neutralization of a Wide Range of HIV-1 Strains by Anti-CD4i Single Chain Variable Fragment (scFv)2016

    • Author(s)
      Tanaka K, Kuwata T, Maruta Y, Ramirez Valdez K P, Alam M, Kawanami Y, Matsushita S
    • Organizer
      HIVR4P 2016
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2016-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Isolation and characterization of HIV-1 envelope glycoprotein in Japanese patients with recent diagnosis.2016

    • Author(s)
      Thida W., Kuwata T., Muntasir A., Tanaka K., Mamun M., Shimuzu M., Kawanami Y., Matsushita S.
    • Organizer
      2nd Kumamoto IRCMS International Symposium.17th Kumamoto AIDS seminar
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Incompatibility of HIV-1 Resistance to Both Cenicriviroc and Neutralizing Antibodies Boston, Massachusetts.2016

    • Author(s)
      Kuwata,T., Enomoto I., Baba M., Matsushita S.
    • Organizer
      Conference on Retroviruses and Opportunistic Infections
    • Place of Presentation
      Boston, USA
    • Year and Date
      2016-02-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Analysis and characterization of HIV-1 envelope glycoprotein in Japanese patients with recent diagnosis2016

    • Author(s)
      Thida W, Kuwata T, Alam M, Tanaka K, Maun M, Shimizu M, Kawanami Y and Matsushita S
    • Organizer
      17th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本
    • Year and Date
      2016-10-31
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Post-attachment neutralization of a broad range of HIV-1 strains by the small antibody fragments targeting CD4-induced (CD4i) epitope2016

    • Author(s)
      Tanaka K, Kuwata T, Takahama S, Alam M, Maruta Y, Ramirez Valdez K P, Shimizu M, Kawanami Y and Matsushita S
    • Organizer
      17th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本
    • Year and Date
      2016-10-31
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] HIV proviral DNA quantification in a cohort of Japanese patients on longterm ART2016

    • Author(s)
      K. Stanoeva, A. Konig, A. Fukuda, Y. Kawanami, T. Kuwata, Y. Satou, S. Matsushita.
    • Organizer
      21st International AIDS Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Construction, purification and analysis of neutralization potency of anti-V3 scFv’s against HIV-1 strains in vitro.2016

    • Author(s)
      Mamun M., Maruta Y., Tanaka K., Muntasir A., Thida W., Kuwata T., Matsushita S.
    • Organizer
      2nd Kumamoto IRCMS International Symposium.17th Kumamoto AIDS seminar
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] CD4+T細胞の分化に対するHIV感染とmiR125bの影響の検討2016

    • Author(s)
      郭悠、南留美、小松真梨子、高濱宗一郎、高濱正吉、桑田岳夫、山本政弘、松下修三
    • Organizer
      第30回日本エイズ学会学術集会・総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2016-11-24
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Dynamics of HIV-1 DNA in long-term treated patients with hematological co-morbidities2016

    • Author(s)
      Stanoeva K, Konig A, Fukuda A, Kawanami Y, Kuwata T, Satou Y, Matsushita S
    • Organizer
      第30回日本エイズ学会学術集会・総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2016-11-24
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Increased total HIV DNA levels in long-term treated patients with hemophilia.2016

    • Author(s)
      Stanoeva K, Konig A, Fukuda A, Kawanami Y, Kuwata T, Satou Y., Matsushita S.
    • Organizer
      第30回日本エイズ学会学術集会・総会.
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Incompatibility of HIV-1 Resistance to Both Cenicriviroc and Neutralizing Antibodies2016

    • Author(s)
      Kuwata T, Enomoto I, Baba M and Matsushita S
    • Organizer
      The annual Conference on Retroviruses and Opportunistic Infections
    • Place of Presentation
      Boston, USA
    • Year and Date
      2016-02-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] ファージ・ライブラリーを用いた抗 V3単クローン抗体のエピトープ解析.2015

    • Author(s)
      平田 泉、桑田岳夫、丸田泰広、田中和樹、Muntasir, A.、松下修三
    • Organizer
      第29回日本エイズ学会学術集会・総会
    • Place of Presentation
      東京ドームホテル、東京
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Impact of gp41 mutations on resistance to B404, a broad neutralizing antibody reactive against a conformational epitope of SIV gp1202015

    • Author(s)
      Kuwata T, Shimizu M, Matsushita S
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Effect of gp41 mutations on the sensitivity to neutralizing antibodies against HIV.2015

    • Author(s)
      Muntasir, A., Kuwata, T., Ramirez, K., Maruta, Y., Tanaka, K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushita, S.
    • Organizer
      第29回日本エイズ学会学術集会・総会.
    • Place of Presentation
      東京ドームホテル、東京
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Potent and broad neutralizing activity of small antibody fragments targeting CD4i (CD4-induced) epitope.2015

    • Author(s)
      Tanaka, K., Kuwata, T., Maruta, Y., Ramirez, K., Alam, M., Egami, Ikumi Y., Enomoto, I., Kawanami, Y., Matsushita. S.
    • Organizer
      The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015)
    • Place of Presentation
      Vancouver, Canada.
    • Year and Date
      2015-07-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04870
  • [Presentation] Impact of gp41 mutations for escape from a broad neutralizing antibody against SIV2015

    • Author(s)
      Kuwata T, Shimizu M, Matsushita S
    • Organizer
      16th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本
    • Year and Date
      2015-10-07
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] CRF01_AE HIV-1 感染症例IgG の交差中和活性の解析2012

    • Author(s)
      園田貴丈、Samatchaya Boonchawalit、田中和樹、丸田康広、Kristel Ramirez、桑田岳夫、松下修三
    • Organizer
      第26回日本エイズ学会学術集会
    • Place of Presentation
      横浜慶應義塾大学
    • Year and Date
      2012-11-24
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] SIV 感染サルから分離された中和抗体 B404 は V3,V4ループを含む Env 立体構造を認識する2012

    • Author(s)
      桑田岳夫、吉村和久、松下修三
    • Organizer
      第26回日本エイズ学会学術集会
    • Place of Presentation
      横浜慶應義塾大学
    • Year and Date
      2012-11-24
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] SIV感染サルから分離された中和抗体B404はV3,V4ループを含むEnv立体構造を認識する2012

    • Author(s)
      桑田岳夫
    • Organizer
      第26回日本エイズ学会学術集会・総会
    • Place of Presentation
      慶應義塾大学日吉キャンパス、横浜市
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] Conformational epitope inbolving V3 and V4 loops is a major tartget for antibody-mediated neutralization in SIV smH635-infected macaques.2012

    • Author(s)
      Kuwata T.
    • Organizer
      13th Kumamoto AIDS Seminar GCOE Joint International Symposium
    • Place of Presentation
      阿蘇グランヴィリオホテル、熊本県阿蘇市
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] gp120 のCD4-induced epitope に結合する中和抗体の解析2012

    • Author(s)
      田中和樹、 桑田岳夫、 丸田泰広、 園田貴丈、Kristel Ramirez 、松下修三
    • Organizer
      第26回日本エイズ学会学術集会
    • Place of Presentation
      横浜 慶應義塾大学
    • Year and Date
      2012-11-26
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] Isolation of Potent Neutralizing Monoclonal Antibodies against V3 Loop from SIV-infected Macaques2011

    • Author(s)
      桑田岳夫
    • Organizer
      AIDS Vaccine 2011
    • Place of Presentation
      Bangkok Convention Centre (Bangkok, Thai)
    • Year and Date
      2011-09-12
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] Biased induction of neutralizing antibodies with particular specificity and gene usage in SIVsmH635FC-infected macaques2011

    • Author(s)
      桑田岳夫
    • Organizer
      12th Kumamoto AIDS Seminar
    • Place of Presentation
      阿蘇リゾートグランヴィリオホテル(熊本県)
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] SIVsmH635FC感染サルにおける特定のエピトープと遺伝子に偏った中和抗体の誘導2011

    • Author(s)
      桑田岳夫
    • Organizer
      第25回日本エイズ学会学術集会
    • Place of Presentation
      ハイアットリージェンシー東京(東京都)
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] Isolation of monoclonal neutralizing antibodies from SIV-infected macaques by phage display2010

    • Author(s)
      桑田岳夫
    • Organizer
      11th Kumamoto AIDS Seminar
    • Place of Presentation
      阿蘇リゾートグランヴィリオホテル(熊本県)
    • Year and Date
      2010-10-07
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] ファーシ・ティスプレイ法による強力な抗SIV中和活性をもつモノクローナル抗体の作製2010

    • Author(s)
      桑田岳夫
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Year and Date
      2010-11-09
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] Contribution of antibody response to effective viral suppression and progression of disvease during SIV infection2010

    • Author(s)
      桑田岳夫
    • Organizer
      International Young Investigator Symposium
    • Place of Presentation
      熊本大学(熊本県)
    • Year and Date
      2010-04-04
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] Generation of monoclonal antibodies with potent neutralizing activity from a SIV-infected macaque2010

    • Author(s)
      桑田岳夫
    • Organizer
      The 28th Annual Symposium for Nonhuman Primate Models for AIDS
    • Place of Presentation
      Westin New Orleans Canal Place (New Orleans, USA)
    • Year and Date
      2010-10-19
    • Data Source
      KAKENHI-PROJECT-22500387
  • [Presentation] SIVサル・モデルを用いた中和抗体の解析

    • Author(s)
      桑田岳夫
    • Organizer
      第17回日本レトロウイルス研究会夏期セミナー
    • Place of Presentation
      伊豆山研修センター(静岡県熱海市)
    • Year and Date
      2014-07-03 – 2014-07-05
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] Mutations in gp41 is Critical to Escape from B404, a Broad Neutralizing Antibody Against SIV, Which Recognizes a V3/V4 Conformational Epitope

    • Author(s)
      Takeo Kuwata, Kazuhisa Yoshimura, Fan Wu, Ilnour Ourmanov, Vanessa M. Hirsch, Masaru Yokoyama, Hironori Sato and Shuzo Matsushita
    • Organizer
      32nd Annual Symposium on Nonhuman Primate Models for AIDS
    • Place of Presentation
      The Nines Hotel (Portland, Oregon, USA)
    • Year and Date
      2014-11-11 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-26430091
  • [Presentation] 強力な抗SIV中和抗体B404からの逃避メカニズムの解析

    • Author(s)
      桑田岳夫、松下修三
    • Organizer
      第28回日本エイズ学会学術集会・総会
    • Place of Presentation
      大阪国際会議場(大阪府北区)
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26430091
  • 1.  IGARASHI Tatsuhiko (90467431)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  MATSUSHITA Shuzo (00199788)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 34 results
  • 3.  佐藤 賢文 (70402807)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  上野 貴将 (10322314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  吉村 和久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  佐藤 裕徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  横山 勝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  藤井 信孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  大石 真也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  前田 洋助
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  滝口 雅文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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