Oikawa Kosuke 及川恒輔

… Alternative Names

OIKAWA Kosuke 及川恒輔

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Researcher Number	70348803
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 和歌山県立医科大学, 医学部, 講師 2017 – 2023: 和歌山県立医科大学, 医学部, 講師 2010 – 2015: 和歌山県立医科大学, 医学部, 講師 2007: Tokyo Medical University, School of Medicine, Assistant Professor 2006: 東京医科大学, 医学部, ポストドクター
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Basic Section 53040:Nephrology-related
Keywords	Principal Investigator 粘液型脂肪肉腫 / キメラ遺伝子 / キメラがんタンパク / HPV / 分子標的治療 / hWAPL / TLS-CHOP / 骨軟部腫瘍 / 癌 / 病理学 … More / 腫瘍関連メカニズム / がんタンパク / Molecular Targeted Therapy / Splicing Variant / Uterine Cervical Cancer / 分子標的療法 / スプライシングバリアント / 子宮頸癌 / 発がん機構 / ＴＬＳーＣＨＯＰ / 腫瘍 … More Except Principal Investigator 免疫染色 / DEC1 / ドライバー遺伝子 / 頭頸部扁平上皮癌 / 頭頚部扁平上皮癌 / 日内リズム / 慢性腎疾患 / CKD / DEC2 / 慢性腎不全 / 時計遺伝子 Less

Basic research to elucidate the novel functions of the chimeric oncoproteins of malignant bone and soft tissue tumors and develop their treatmentsPrincipal Investigator
- Principal Investigator
  
  及川恒輔
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Wakayama Medical University
Identification and clinical application of driver candidate genes DEC1, Klo, KRT222 in head and neck squamous cell carcinoma
- Principal Investigator
  
  佐藤冬樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Shizuoka Cancer Center Research Institute
キメラがんタンパクの多層的腫瘍関連機構の解明と治療への応用を目指した基礎研究Principal Investigator
- Principal Investigator
  
  及川恒輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Wakayama Medical University
Basic research of the significance of clock gene DEC1 decreases in chronic kidney disease progression
- Principal Investigator
  
  Sato Fuyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shizuoka Cancer Center Research Institute
Basic Research on mechanisms of multistep tumorigenesis in myxoid liposarcoma and its clinical applicationsPrincipal Investigator
- Principal Investigator
  
  OIKAWA Kosuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Wakayama Medical University
Research on mechanisms of multistep tumorigenesis by TLS-CHOP chimeric oncoprotein and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  OIKAWA KOSUKE
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Wakayama Medical University
Basic research for investigation of novel oncogenic mechanism by TLS-CHOP chimeric oncoprotein and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  OIKAWA Kosuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Wakayama Medical University
Analysis of Physical Functions of the Novel Onoogene h WAPL, and its Applications in Diagnosis and TherapyPrincipal Investigator
- Principal Investigator
  
  OIKAWA Kosuke
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical University

[Journal Article] Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder2024
- Author(s)
  Sato F, Bhawal UK, Oikawa K, Muragaki Y
- Journal Title
  
  BMC Molecular and Cell Biology
  
  Volume: 25(1) Issue: 1 Pages: 1-1
- DOI
  10.1186/s12860-023-00497-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10238, KAKENHI-PROJECT-22K09384, KAKENHI-PROJECT-23K09162, KAKENHI-PROJECT-21K10237
[Journal Article] Suppression of antitumor cytokine IL-24 by PRG4 and PAI-1 may promote myxoid liposarcoma cell survival.2023
- Author(s)
  Kosuke Oikawa, Masahiko Kuroda, Shogo Ehata.
- Journal Title
  
  Biomedical Reports
  
  Volume: 19 Issue: 3 Pages: 60-60
- DOI
  10.3892/br.2023.1642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09384, KAKENHI-PROJECT-21H02706
[Journal Article] Differential immunohistochemical expression of DEC1, CK-1ε, and CD44 in oral atypical squamous epithelium and carcinoma in situ2022
- Author(s)
  Fuyuki Sato , Ujjal K Bhawal, Shoko Osaki, Nao Sugiyama , Kosuke Oikawa , Yasuteru Muragaki
- Journal Title
  
  Mol Med Rep
  
  Volume: 25(5):159 Issue: 5 Pages: 1-6
- DOI
  10.3892/mmr.2022.12676
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08659, KAKENHI-PROJECT-19K08710, KAKENHI-PROJECT-21K10238, KAKENHI-PROJECT-22K09384
[Journal Article] Potential role of DEC1 in cervical cancer cells involving overexpression and apoptosis2020
- Author(s)
  Sato F, Bhawal UK, Sugiyama N, Osaki S, Oikawa K, Muragaki Y
- Journal Title
  
  Clocks & Sleep
  
  Volume: 2(1) Issue: 1 Pages: 26-38
- DOI
  10.3390/clockssleep2010004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09922, KAKENHI-PROJECT-17K08768, KAKENHI-PROJECT-17K12059, KAKENHI-PROJECT-19K08710
[Journal Article] Suppression of MKL1 promotes adipocytic differentiation and reduces the proliferation of myxoid liposarcoma cells.2020
- Author(s)
  Kamikawa Y, Yokota K, Oikawa K, Sato F, Muragaki Y.
- Journal Title
  
  Oncol letters
  
  Volume: 20 Issue: 6 Pages: 1-7
- DOI
  10.3892/ol.2020.12232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08710, KAKENHI-PROJECT-20K08659
[Journal Article] Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression.2015
- Author(s)
  Sun Y, Nakanishi M, Sato F, Oikawa K, Muragaki Y, Zhou G.
- Journal Title
  
  BBRC
  
  Volume: 456 Issue: 3 Pages: 721-726
- DOI
  10.1016/j.bbrc.2014.12.039
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590488, KAKENHI-PROJECT-25460480
[Journal Article] Smad3 plays an inhibitory role in phosphate-induced vascular smooth muscle cell calcification.2014
- Author(s)
  A. Shimokado, Y. Sun, M. Nakanishi, F. Sato, K. Oikawa, T. Akasaka, Y. Muragaki.
- Journal Title
  
  Experimental and Molecular Pathology
  
  Volume: 97 Issue: 3 Pages: 458-464
- DOI
  10.1016/j.yexmp.2014.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460480
[Journal Article] Elevated serum 1,25(OH)2-vitamin D3 level attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in kl/kl mice.2014
- Author(s)
  Sun Y, Zhou G, Gui T, Shimokado A, Nakanishi M, Oikawa K, Sato F, Muragaki Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 6563-6563
- DOI
  10.1038/srep06563
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590488, KAKENHI-PROJECT-25460480
[Journal Article] Identification of a novel role of Septin 10 in Paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 4 Pages: 821-827
- DOI
  10.1111/j.1349-7006.2012.02221.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592146, KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24370058
[Journal Article] Fibulin-5 Protein Is Reduced in the Lung of Patients with Spontaneous Pneumothorax Who Are Under 25 Years Old2012
- Author(s)
  Y. Hirai, Y. Muragaki, S. Itoh, K. Oikawa, M. Juri, T. Kondo, Y. Okamura
- Journal Title
  
  ATCS
  
  Volume: 18 Issue: 3 Pages: 200-205
- DOI
  10.5761/atcs.oa.11.01758
- NAID
  10030789489
- ISSN
  1341-1098, 2186-1005
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367
[Journal Article] MicroRNAs that target Ca2+ transporters are involved in vascular smooth muscle cell calcification2012
- Author(s)
  T. Gui, G. Zhou, Y. Sun, A. Shimokado, S. Itoh, K. Oikawa, Y. Muragaki
- Journal Title
  
  Lab. Invest
  
  Volume: 92 Issue: 9 Pages: 1250-1259
- DOI
  10.1038/labinvest.2012.85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-22590896, KAKENHI-PROJECT-24590488
[Journal Article] A novel oncogenic pathway by TLS-CHOP involving repression of MDA-7/IL-24 expression2012
- Author(s)
  K. Oikawa, M. Tanaka, S. Itoh, M. Takanashi, T. Ozaki, Y. Muragaki, M. Kuroda
- Journal Title
  
  Br. J. Cancer
  
  Volume: 106 Issue: 12 Pages: 1976-1979
- DOI
  10.1038/bjc.2012.199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
[Journal Article] TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma2012
- Author(s)
  N. Borjigin, S. Ohno, W. Wu, M. Tanaka, R. Suzuki, K. Fujita, M. Takanashi, K. Oikawa, T. Goto, T. Motoi, T. Kosaka, K. Yamamoto, M. Kuroda
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 427 Issue: 2 Pages: 355-360
- DOI
  10.1016/j.bbrc.2012.09.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
[Journal Article] Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing2011
- Author(s)
  M. Kawakatsu, S. Kanno, T. G u i, Z. Gai, S. Itoh, H. Tanishima, K. Oikawa, Y. Muragaki
- Journal Title
  
  Exp. Mol. Pathol
  
  Volume: 90 Issue: 1 Pages: 107-115
- DOI
  10.1016/j.yexmp.2010.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367
[Journal Article] Aberrant expression of the P2 promoter-specific transcript Runx1 in epiphyseal cartilage of Trps1-null mice2011
- Author(s)
  S. Kanno, T. Gui, S. Itoh, Z. Gai, Y. S u n , K. Oikawa, M. Yoshida, Y. Muragaki
- Journal Title
  
  Exp. Mol. Pathol
  
  Volume: 90 Issue: 2 Pages: 143-148
- DOI
  10.1016/j.yexmp.2010.11.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367
[Journal Article] SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo2010
- Author(s)
  R. Nishioka, S. Itoh, T. Gui, Z. G a i , K. Oikawa, M. Kawai, M. Tani, H. Yamaue, Y. Muragaki
- Journal Title
  
  Exp. Mol. Pathol
  
  Volume: 89 Pages: 149-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367
[Journal Article] Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development2010
- Author(s)
  M. Shigoka, A. Tsuchida, T. Matsudo , Y. Nagakawa, H. Saito, Y. Suzuki, T. Aoki, Y. Murakami, H. Toyoda, T. Kumada, R. Bartenschlager, N. Kato, M. Ikeda, T. Takashina, M. Tanaka, R. Suzuki, K. Oikawa, M. Takanashi, M. Kuroda
- Journal Title
  
  Pathol. Int
  
  Volume: 60 Issue: 5 Pages: 351-357
- DOI
  10.1111/j.1440-1827.2010.02526.x
- NAID
  10029331782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367
[Journal Article] Trps1 haploinsufficiency promotes renal fibrosis by increasing Arkadia expression2010
- Author(s)
  Z. Gai, G. Zhou, T. Gui, S. Itoh, K. Oikawa, K. Uetani, Y. Muragaki
- Journal Title
  
  J. Am. Soc. Nephrol
  
  Volume: 21 Issue: 9 Pages: 1468-1476
- DOI
  10.1681/asn.2009121201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫における抗腫瘍性サイトカインIL-24の発現抑制2023
- Author(s)
  及川恒輔、江幡正悟、村垣泰光
- Organizer
  第51回和歌山悪性腫瘍研究会
- Data Source
  KAKENHI-PROJECT-22K09384
[Presentation] 抗腫瘍性サイトカインIL-24は粘液型脂肪肉腫においてPRG4とPAI-1による2重機構で抑制される2023
- Author(s)
  及川恒輔、黒田雅彦、江幡正悟
- Organizer
  第46回に本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K09384
[Presentation] A novel molecular mechanism to repress the anti-tumor cytokine IL-24 for maintenance of myxoid liposarcoma cells.2023
- Author(s)
  Kosuke Oikawa, Masahiko Kuroda, Shogo Ehata.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09384
[Presentation] A novel molecular mechanism for inhibition of anti-tumor cytokine IL-24 expression in myxoid liposarcoma cells.2022
- Author(s)
  Kosuke Oikawa, Fuyuki Sato, Masahiko Kuroda, Shogo Ehata.
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09384
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPの新規下流分子SOX11の同定2022
- Author(s)
  及川恒輔、黒田雅彦、村垣泰光、江幡正悟
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K09384
[Presentation] 粘液型脂肪肉腫においてTLS-CHOP は抗腫瘍性サイトカインIL-24 を多重機構で抑制する2019
- Author(s)
  及川恒輔、佐藤冬樹、黒田雅彦、尾崎敬、村垣泰光
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] CK14 and CK17 are expressed in invasive cells in human pancreatic cancer tissues2019
- Author(s)
  佐藤冬樹, バワールウジャール, 及川恒輔, 村垣泰光
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K08710
[Presentation] サイトケラチン14 とサイトケラチン17 は、膵癌浸潤部の微小集塊状領域において高発現している2019
- Author(s)
  佐藤冬樹、バワールウジャール、及川恒輔、村垣泰光
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] Promotion of adipocyte differentiation of myxoid liposarcoma cells by inhibition of MKL1 expression2019
- Author(s)
  Kosuke Oikawa, Fuyuki Sato, Yasuteru Muragaki
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPの新規下流分子の検索2019
- Author(s)
  及川恒輔、木下洸樹、中川裕貴、佐藤冬樹、尾崎敬、村垣泰光
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] 子宮頸癌においてBHLH 型転写因子DEC1 発現は幹細胞マーカーSOX2 とc-MYC 発現を制御する2019
- Author(s)
  杉山奈生、佐藤冬樹、尾崎祥子、バワールクマール、及川恒輔、村垣泰光
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] 子宮頸癌においてBHLH型転写因子DEC1発現は幹細胞マーカーSOX2 とc-MYC発現を制御する2019
- Author(s)
  杉山奈生, 佐藤冬樹, 杉山奈生, バワールウジャール, 及川恒輔, 村垣泰光
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K08710
[Presentation] Smad3 suppresses epitherial cell migration and proliferation via the clock gene Dec12019
- Author(s)
  Fuyuki Sato, Ujjarl Bhawal, Kosuke Oikawa, Yasuteru Muragaki
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] Analysis of dual mechanism of IL-24 suppression in myxoid liposarcoma cells.2018
- Author(s)
  Kosuke Oikawa, Fuyuki Sato, Yasuteru Muragaki.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] マイクロ波による細胞現象の分子生物学的検討－甲状腺癌細胞株を使用して－2018
- Author(s)
  尾﨑敬，田伏克惇，渡邊雄也, 中西雅子, 佐藤冬樹，及川恒輔，覚道健一，村垣泰光
- Organizer
  第37回Microwave Surgery 研究会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] マイクロ波効果による細胞現象の分子生物学的検討－甲状腺癌細胞株を使用して－2018
- Author(s)
  尾﨑敬，田伏克惇，渡邊雄也, 中西雅子, 佐藤冬樹，及川恒輔，覚道健一，村垣泰光
- Organizer
  第61回日本臨床検査医学会近畿支部総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] CK14 and CK17 are partially expressed in microaggregate form of invasive cells of pancreatic cancer.2018
- Author(s)
  Kosuke Mori, Fuyuki Sato, Kosuke Oikawa, Yasuteru Muragaki.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] Clock geneDEC1 regulates the expression of stem cell marker genes SOX2 and c-MYC in cervical cancer.2018
- Author(s)
  Fuyuki Sato, Ujjal Bhawal, Kosuke Oikawa, Yasuteru Muragaki.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] 粘液型脂肪肉腫における腫瘍細胞維持及び脂肪分化阻害に関わる分子機構の検討2018
- Author(s)
  及川恒輔、神川陽平、横田健斗、佐藤冬樹、尾崎　敬、村垣泰光
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] マイクロ波効果で誘導されて未知なる細胞の検討―甲状腺癌細胞株を使用して―2017
- Author(s)
  1.尾﨑敬，田伏克惇，渡邊雄也，中西雅子，佐藤冬樹，及川恒輔，覚道健一，村垣泰光
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] BHLH transcription factor DEC1 and DEC2 play important roles in cancer cell metabolism2017
- Author(s)
  Fuyuki Sato, Kosuke Oikawa, Yasuteru Muragaki.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] 粘液型脂肪肉腫の新規腫瘍関連機構の検討2017
- Author(s)
  及川恒輔、佐藤冬樹、尾崎敬、村垣泰光
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] 転写因子ＤＥＣ１とＤＥＣ２は日内リズムと腫瘍の発育進展をクロストークする2017
- Author(s)
  佐藤冬樹、Ujjal Bhawal、及川恒輔、村垣泰光
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] Analysis of multiple mechanisms of IL-24 suppression that is essential for growth of myxoid liposarcoma cells.2017
- Author(s)
  Kosuke Oikawa, Fuyuki Sato, Yasuteru Muragaki.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08768
[Presentation] Identification of novel molecular pathways required for the growth of TLS-CHOP-expressing myxoid liposarcoma cells.2015
- Author(s)
  Kosuke Oikawa, Masakatsu Takanashi, Fuyuki Sato, Masahiko Kuroda, Yasuteru Muragaki.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 粘液型脂肪肉腫特異的キメラ遺伝子TLS-CHOPに制御される新規分子メカニズムの検討.2015
- Author(s)
  及川恒輔, 田中正視, 尾崎敬, 黒田雅彦, 村垣泰光.
- Organizer
  第38回日本分子生物学会年会第88回日本生化学会大会合同大会(BMB2015)
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] BHLH transcription factor DEC2 negatively regulates TWIST1 and VEGF under hypoxia.2015
- Author(s)
  Fuyuki Sato, Ujjal Bhawal, Kosuke Oikawa, Yasuteru Muragaki
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 甲状腺癌細胞株に対するマイクロ波効果－誘導された未知なる細胞の検討－.2015
- Author(s)
  尾崎敬, 田伏克惇, 渡邊雄也, 南條佐輝子, 張穎哲, 中西雅子, 佐藤冬樹, 及川恒輔, 覚道健一, 村垣泰光.
- Organizer
  第43回和歌山悪性腫瘍研究会
- Place of Presentation
  日本赤十字和歌山医療センター
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 子宮頸癌関連タンパクWAPLによるエピジェネティック制御への関与.2014
- Author(s)
  及川恒輔、丹羽麻也子、水崎杏奈、孫玉静、中西雅子、佐藤冬樹、尾崎　敬、村垣泰光.
- Organizer
  第82回和歌山医学会総会
- Place of Presentation
  和歌山県立医科大学(和歌山県和歌山市)
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] BHLH型転写因子DEC1の膵癌におけるEMT機能.2014
- Author(s)
  佐藤冬樹、中西雅子、及川恒輔、村垣泰光.
- Organizer
  第82回和歌山医学会総会
- Place of Presentation
  和歌山県立医科大学(和歌山県和歌山市)
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] マイクロ波効果－基礎的研究－　甲状腺癌細胞株に対する非熱的マイクロ波効果の検討2013
- Author(s)
  尾崎敬，田伏克惇，孫玉静，下角あい子，伊藤俊治，及川恒輔，覚道健一，村垣泰光.
- Organizer
  Microwave Surgery研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 甲状腺は再生する臓器か？－マウス動物実験から検討－2013
- Author(s)
  尾崎敬，覚道健一，伊藤俊治，及川恒輔，村垣泰光，木村芝生子.
- Organizer
  日本内分泌学会学術総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPによる多段階発がん機構の検討2013
- Author(s)
  及川恒輔, 伊藤俊治, 田中正視, 高梨正勝, 孫玉静, 尾崎敬, 黒田雅彦, 村垣泰光.
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 甲状腺癌細胞株に対する非熱的マイクロ波効果の検討2013
- Author(s)
  尾崎敬，覚道健一，Gui Ting，Sun Yujing，下角あい子，伊藤俊治，及川恒輔，田伏克惇，村垣泰光.
- Organizer
  日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] Novel molecular pathways in TLS-CHOP-dependent mechanism for myxoid liposarcoma tumorigenesis and tumor progression2013
- Author(s)
  Kosuke Oikawa, Masakatsu Takanashi, Masahiko Kuroda, Yasuteru Muragaki.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] TLS-CHOP represses expression of the antitumor cytokine MDA-7/IL24 in myxoid liposarcoma2012
- Author(s)
  及川恒輔
- Organizer
  日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] Wapl regulates HP1 expression and levels of various histone H3 tail modifications2012
- Author(s)
  及川恒輔
- Organizer
  日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡(福岡県)
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPが関わる多段階発がん機構の探究2012
- Author(s)
  及川恒輔
- Organizer
  和歌山悪性腫瘍研究会
- Place of Presentation
  和歌山ビッグ愛(和歌山県)
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] コヒーシン制御タンパクWaplの新しい機能の検討2011
- Author(s)
  及川恒輔
- Organizer
  和歌山医学会総会
- Place of Presentation
  和歌山県立医科大学(和歌山県)
- Year and Date
  2011-07-10
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] A novel oncogenic mechanism of the chimeric oncoprotein TLS-CHOP mediated by a tumor suppressor protein MDA-7/IL242011
- Author(s)
  及川恒輔
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] Analysis of the novel molecular function of the cohesin-associated protein Wap12011
- Author(s)
  及川恒輔
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫における分子治療の可能性を探る2011
- Author(s)
  及川恒輔
- Organizer
  日本バイオセラピィ学会学術集会総会
- Place of Presentation
  ダイワロイネットホテル和歌山
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] コヒーシン制御タンパクWap1の新しい機能の検討2011
- Author(s)
  及川恒輔
- Organizer
  和歌山医学会総会
- Place of Presentation
  和歌山県立医科大学(和歌山県)
- Year and Date
  2011-07-10
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] Analysis of the novel molecular function of the cohesin-associated protein Wapl2011
- Author(s)
  及川恒輔
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫における分子治療の可能性を探る2011
- Author(s)
  及川恒輔
- Organizer
  日本バイオセラピィ学会学術集会総会
- Place of Presentation
  ダイワロイネットホテル和歌山(和歌山県)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫におけるキメラタンパクTLS-CHOPによる腫瘍化機構の検討2010
- Author(s)
  及川恒輔
- Organizer
  和歌山医学会総会
- Place of Presentation
  和歌山
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] The PRG4 variants associated with sarcoma development have a potential to be therapeutic targets2010
- Author(s)
  及川恒輔
- Organizer
  日本分子生物学会年会日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫におけるキメラタンパクTLS-CHOPによる腫瘍化機構の検討2010
- Author(s)
  及川恒輔
- Organizer
  和歌山医学会総会
- Place of Presentation
  和歌山県立医科大学(和歌山県)
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] The PRG4 variants associated with sarcoma development have a potential to be therapeutic targets2010
- Author(s)
  及川恒輔
- Organizer
  日本分子生物学会年会日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] Mechanism of Cell Growth Inhibition of Myxoid Liposarcoma by TLS-CHOP specific siRNA2007
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] ダイオキシンはAhRを介して染色体テリトリーを変動させる2007
- Author(s)
  及川恒輔, 他
- Organizer
  第66回目本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Analysis of Tumor Formation Activity of G Protein-Coupled Receptor Kinase 4 in Breast Carcinogenesis2007
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  The 96th Annual Meeting of the Japanese Society of Pathology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] 乳癌におけるG protein-coupled Receptor Kinase 4の腫瘍化能の検討2007
- Author(s)
  及川恒輔, 他
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] ダイオキシンはAhRを介して染色体テリトリーを変動させる2007
- Author(s)
  及川恒輔, 他
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Dioxin Interferes in Chromosomal Positioning through the Aryl Hydrocarbon Receptor2007
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  The 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] TLS-CHOP特異的siRNAによる粘液型脂肪肉腫の細胞増殖抑制機構2007
- Author(s)
  及川恒輔, 他
- Organizer
  第30回日本分子生物学会年会第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] TLS-CHOP特異的siRNAによる粘液型脂肪肉腫の細胞増殖抑制機構2007
- Author(s)
  及川恒輔, 他
- Organizer
  日本分子生物学会年会日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Analysis of Anti-cancer Effects of the Specific siRNAs2006
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  MBSJ 2006 Forum
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Potential of DOL54 for Molecular Target of Myxoid Liposarcoma Therapy2006
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  The 65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Analysis of the Alternative Spliced Variants of the Essential Gene, hWAPL2006
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  The 95th Annual Meeting of the Japanese Society of Pathology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Characterization of the HWAP1, Gene that has Oncogenic Characteristics2006
- Author(s)
  Kosuke, Oikawa, et. al.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] 様々な特異的siRNAの抗腫瘍効果の検討2006
- Author(s)
  及川恒輔, 他
- Organizer
  日本分子生物学会2006フォーラム
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] 必須遺伝子hWAPLのスプライスバリアントの解析2006
- Author(s)
  及川恒輔, 他
- Organizer
  第95回日本病理学会総会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] 粘液型脂肪肉腫におけるDOL54を標的分子とした分子治療の可能性2006
- Author(s)
  及川恒輔, 他
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Characterization of the hWAPL gene that has oncogenic characteristics2006
- Author(s)
  及川恒輔, 他
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and FAOBMB Congress
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590382
[Presentation] Wapl regulates HP1 expression and levels of various histone H3 tail modifications.
- Author(s)
  及川恒輔
- Organizer
  日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPが関わる多段階発がん機構の探究
- Author(s)
  及川恒輔
- Organizer
  和歌山悪性腫瘍研究会
- Place of Presentation
  和歌山ビッグ愛（和歌山県）
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] MAGED2 plays important roles in tumor cell survival.
- Author(s)
  Fuyuki Sato, Kosuke Oikawa, Yasuteru Muragaki, Yanping Zhang.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] TLS-CHOP represses expression of the antitumor cytokine MDA-7/IL24 in myxoid liposarcoma.
- Author(s)
  及川恒輔
- Organizer
  日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館（北海道）
- Data Source
  KAKENHI-PROJECT-22590367
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPによる発がん分子メカニズム
- Author(s)
  及川恒輔, 伊藤俊治, 孫玉静, 下角あい子, 尾崎敬, 村垣泰光.
- Organizer
  和歌山医学会総会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] Analysis of a novel molecular pathway induced by TLS-CHOP for myxoid liposarcoma tumorigenesis and tumor progression.
- Author(s)
  Kosuke Oikawa, Masakatsu Takanashi, Masako Nakanishi, Fuyuki Sato, Masahiko Kuroda, Yasuteru Muragaki.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 粘液型脂肪肉腫特異的キメラがんタンパクTLS-CHOPの下流分子の検討.
- Author(s)
  及川恒輔、田中正視、高梨正勝、尾崎敬、黒田雅彦、村垣泰光.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 甲状腺癌細胞株に対する非熱的マイクロ波効果の検討
- Author(s)
  尾崎敬, Sun Yujing, 下角あい子, 伊藤俊治, 及川恒輔, 村垣泰光, 田伏克惇, 覚道健一.
- Organizer
  和歌山医学会総会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-25460480
[Presentation] 甲状腺未分化癌細胞株に対する非熱的マイクロ波効果の検討.
- Author(s)
  尾崎敬，田伏克惇，渡邊雄也, 孫玉静，下角あい子，中西雅子, 佐藤冬樹，及川恒輔，覚道健一，村垣泰光.
- Organizer
  第33回Microwave Surgery 研究会
- Place of Presentation
  たかつき京都ホテル(大阪府高槻市)
- Year and Date
  2014-09-11 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25460480

1. MURAGAKI Yasuteru (40190904)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
2. Sato Fuyuki (60400131)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. 藤本勝巳 (40294566)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Bhawal Ujjal (50433339)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ISAKA Keiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. バワールウジャール

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 西洋孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 黒田雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oikawa Kosuke 及川 恒輔

OIKAWA Kosuke 及川 恒輔

Research Projects

Research Products

Co-Researchers

Basic research to elucidate the novel functions of the chimeric oncoproteins of malignant bone and soft tissue tumors and develop their treatmentsPrincipal Investigator

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Identification and clinical application of driver candidate genes DEC1, Klo, KRT222 in head and neck squamous cell carcinoma

Principal Investigator

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キメラがんタンパクの多層的腫瘍関連機構の解明と治療への応用を目指した基礎研究Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Basic research of the significance of clock gene DEC1 decreases in chronic kidney disease progression

Principal Investigator

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Review Section

Research Institution

Basic Research on mechanisms of multistep tumorigenesis in myxoid liposarcoma and its clinical applicationsPrincipal Investigator

Principal Investigator

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Research Institution

Research on mechanisms of multistep tumorigenesis by TLS-CHOP chimeric oncoprotein and its clinical applicationPrincipal Investigator

Principal Investigator

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Research Institution

Basic research for investigation of novel oncogenic mechanism by TLS-CHOP chimeric oncoprotein and its clinical applicationPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Analysis of Physical Functions of the Novel Onoogene h WAPL, and its Applications in Diagnosis and TherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Journal Article] Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of antitumor cytokine IL-24 by PRG4 and PAI-1 may promote myxoid liposarcoma cell survival.2023

Author(s)

Journal Title

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[Journal Article] Differential immunohistochemical expression of DEC1, CK-1ε, and CD44 in oral atypical squamous epithelium and carcinoma in situ2022

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[Journal Article] Potential role of DEC1 in cervical cancer cells involving overexpression and apoptosis2020

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[Journal Article] Suppression of MKL1 promotes adipocytic differentiation and reduces the proliferation of myxoid liposarcoma cells.2020

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[Journal Article] Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression.2015

Author(s)

Oikawa Kosuke 及川恒輔

OIKAWA Kosuke 及川恒輔