Onuma Kazuo 小沼一雄

… Alternative Names

Kazuo Onuma 小沼一雄

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Researcher Number	70356731
Affiliation (Current)	2025: 鶴見大学, 歯学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 鶴見大学, 歯学部, 非常勤講師 2017 – 2018: 国立研究開発法人産業技術総合研究所, 生命工学領域, 上級主任研究員 2016: 国立研究開発法人産業技術総合研究所, 健康工学研究部門, 上級主任研究員
Review Section/Research Field	Principal Investigator Basic Section 30010:Crystal engineering-related / Crystal engineering Except Principal Investigator Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 30010:Crystal engineering-related
Keywords	Principal Investigator リン酸八カルシウム / アパタイト / 結晶－アモルファス複合体 / 大領域う蝕治療 / 細胞認識機能 / アモルファスリン酸カルシウム / 半結晶性アパタイト / 回転双晶 / 構造共有型エピタキシー / 歯周組織再生 … More / 根面う蝕修復剤 / 構造変調型アパタイト / 細胞とACPの相互作用 / 根面う蝕修復 / ACP / 逆相転移 / 成長速度 / コヒーレント構造 / フッ素 / 逆方向相転移 / 再生医学 / 歯学 / 生体材料 / 結晶工学 / 結晶成長 / 一方向配向 / ナノロッド型結晶 / geometrical selection / フッ素イオン / 骨代替材料 / エナメルタンパク質 / 基板成形圧力 / 象牙質再生 / フッ素イオン濃度 / OCP / 人工象牙質 / 選択的方位結晶成長 / 相転移 / 圧縮成形基板 / アモルファスナノ粒子 / 人工エナメル質 … More Except Principal Investigator 歯周組織 / ヒト臍帯血管周囲細胞 / 歯根膜 / ジルコニア / チタン / サイトカイン / インプラント / セメント質 / 再生医療 / 非晶質リン酸カルシウム / 歯科インプラント Less

Development of next-generation dental implant that regenerate periodontal tissue through phase transformation of amorphous calcium phosphate
- Principal Investigator
  
  斉藤まり
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 30010:Crystal engineering-related
- Research Institution
  Tsurumi University
Creation of Semi-crystalline Apatite Amorphous Complexes with Cell Recognition Functions and Their Application to Large Area Caries RepairPrincipal Investigator
- Principal Investigator
  
  小沼一雄
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 30010:Crystal engineering-related
- Research Institution
  Tsurumi University
Basic research on the development of periodontal tissue regenerative implants using titanium-binding proteins and cytokines
- Principal Investigator
  
  山越康雄
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Tsurumi University
Root-caries repair agent developed using reverse phase transformation from apatite to octacalcium phosphatePrincipal Investigator
- Principal Investigator
  
  Onuma Kazuo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 30010:Crystal engineering-related
- Research Institution
  Tsurumi University
Artificial enamel induced by phase transformation of amorphous nanoparticlesPrincipal Investigator
- Principal Investigator
  
  Kazuo Onuma
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Crystal engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Rapid regeneration of artificial enamel using laser-assisted biomineralization: With and without mesoscale hierarchy in hydroxyapatite rods2024
- Author(s)
  Kazuo Onuma, Pal Aniruddha, Miyabi Makino, Ikuko Sakamaki, Maki Nakamura, Saori Tanaka, Hirofumi Miyaji, Ayako Oyane
- Journal Title
  
  Materials Today Communications
  
  Volume: 38 Pages: 108030-108030
- DOI
  10.1016/j.mtcomm.2024.108030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05349, KAKENHI-PROJECT-22KF0412, KAKENHI-PLANNED-22H05148
[Journal Article] Synergistic effect of FGF-2 and TGF-β1 on the mineralization of human umbilical cord perivascular cells2023
- Author(s)
  Yabe Masahiro、Karakida Takeo、Onuma Kazuo、Yamamoto Ryuji、Chiba-Ohkuma Risako、Asada Sakurako、Yamakoshi Yasuo、Gomi Kazuhiro
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 156 Pages: 105826-105826
- DOI
  10.1016/j.archoralbio.2023.105826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09945, KAKENHI-PROJECT-22K10027, KAKENHI-PROJECT-20K05349
[Journal Article] Cementum is key to periodontal tissue regeneration: A review on apatite microstructures for creation of novel cementum‐based dental implants2023
- Author(s)
  Saito Mari M.、Onuma Kazuo、Yamakoshi Yasuo
- Journal Title
  
  genesis
  
  Volume: e23514 Issue: 3-4 Pages: 23514-23514
- DOI
  10.1002/dvg.23514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19078, KAKENHI-PROJECT-22K10027, KAKENHI-PROJECT-20K05349
[Journal Article] Repurposing MDZ as a tool for tissue regeneration in dental cells2022
- Author(s)
  Y. Yamakoshi, R. Chiba-Ohkuma, Y. Hidaka, K. Onuma, R. Yamamoto, M. M. Saito, T. Karakida
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 64 Issue: 1 Pages: 37-42
- DOI
  10.1016/j.job.2021.10.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05349, KAKENHI-PROJECT-21K09945, KAKENHI-PROJECT-19K19078
[Journal Article] Coherent surface structure induces unique epitaxial overgrowth of metastable octacalcium phosphate on stable hydroxyapatite at critical fluoride concentration2021
- Author(s)
  Kazuo Onuma, Mari M. Saito, Yasuo Yamakoshi, Mayumi Iijima, Yu Sogo, Koichi Momma
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 125 Pages: 333-344
- DOI
  10.1016/j.actbio.2021.02.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05349, KAKENHI-PROJECT-19K19078, KAKENHI-PROJECT-18K09627
[Journal Article] New insights into bioactivity of ceria-stabilized zirconia: Direct bonding to bone-like hydroxyapatite at nanoscale2021
- Author(s)
  Mari M. Saito, Kazuo Onuma, Ryuji Yamamoto, Yasuo Yamakoshi
- Journal Title
  
  Materials Science & Engineering C
  
  Volume: 121 Pages: 111665-111665
- DOI
  10.1016/j.msec.2020.111665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05349, KAKENHI-PROJECT-19K19078, KAKENHI-PROJECT-18K09627
[Journal Article] Potential for drug repositioning of midazolam for dentin regeneration.2019
- Author(s)
  Karakida T, Onuma K, Saito MM, Yamamoto R, Chiba T, Chiba R, Hidaka Y, Abe-Fujii K, Kawahara H and Yamakoshi Y
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 20(3) Issue: 3 Pages: 670-689
- DOI
  10.3390/ijms20030670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09627, KAKENHI-PROJECT-16K04954, KAKENHI-PROJECT-16K11663
[Journal Article] Octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in metastable calcium phosphate solution2019
- Author(s)
  Iijima Mayumi, Onuma Kazuo
- Journal Title
  
  Biominerarization-From Molecular and Nano-structural Analyses to Environmental Science
  
  Volume: - Pages: 267-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04954
[Journal Article] Particle-size-dependent octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in calcium phosphate solution2018
- Author(s)
  Mayumi Iijima, Kazuo Onuma
- Journal Title
  
  Ceramics International
  
  Volume: 44 Issue: 2 Pages: 2146-2157
- DOI
  10.1016/j.ceramint.2017.10.167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04954
[Journal Article] Octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in metastable calcium phosphate solution2018
- Author(s)
  Mayumi Iijima, Kazuo Onuma
- Journal Title
  
  Proceedings of Biomineralization XIV
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04954
[Journal Article] Roles of Fluoride on Octacalcium Phosphate and Apatite Formation on Amorphous Calcium Phosphate Substrate2018
- Author(s)
  Mayumi Iijima, Kazuo Onuma
- Journal Title
  
  Crystal Growth & Design
  
  Volume: 18 Issue: 4 Pages: 2279-2288
- DOI
  10.1021/acs.cgd.7b01717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04954
[Journal Article] Artificial enamel induced by phase transformation of amorphous nanoparticles2017
- Author(s)
  Kazuo Onuma, Mayumi Iijima
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 2711-2711
- DOI
  10.1038/s41598-017-02949-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K04954
[Journal Article] Nanoparticles in β-tricalcium phosphate substrate enhance modulation of and structure and composition of an octacalcium phosphate grown layer2017
- Author(s)
  Kazuo Onuma, Mayumi Iijima
- Journal Title
  
  CrystEngComm
  
  Volume: 19 Issue: 44 Pages: 6660-6672
- DOI
  10.1039/c7ce01563a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04954
[Patent] β-TCP基材とOCP結晶層を含む複合体及びその製造方法2019
- Inventor(s)
  小沼一雄
- Industrial Property Rights Holder
  産業技術総合研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-546681
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16K04954
[Patent] 人工エナメル質の形成方法2019
- Inventor(s)
  小沼一雄
- Industrial Property Rights Holder
  産業技術総合研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-512410
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16K04954
[Patent] アモルファスナノ粒子の相転移を利用した人工エナメル質の迅速作成技術開発2018
- Inventor(s)
  小沼一雄
- Industrial Property Rights Holder
  小沼一雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-051417
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K04954
[Patent] β-TCP基板上へのOCP結晶層の作成及び成長層の構造と組成の制御2017
- Inventor(s)
  小沼一雄
- Industrial Property Rights Holder
  小沼一雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-195340
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K04954
[Patent] アモルファスナノ粒子の相転移を利用した人工エナメル質の迅速作成技術開発2017
- Inventor(s)
  小沼一雄
- Industrial Property Rights Holder
  小沼一雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-080505
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K04954
[Presentation] Octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in metastable calcium phosphate solution2017
- Author(s)
  Mayumi Iijima, Kazuo Onuma
- Organizer
  Biomineralization XIV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K04954
[Presentation] Oriented Hydroxyapatite Nanorod Array on Amorphous Nanoparticle Substrate2017
- Author(s)
  Kazuo Onuma, Mayumi Iijima
- Organizer
  Biomineralization XIV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K04954

1. 斉藤まり (60739332)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. 山越康雄 (20182470)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 唐木田丈夫 (40367305)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 山本竜司 (20410053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 大熊理紗子 (50804887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Iijima Mayumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 千葉理紗子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Onuma Kazuo 小沼 一雄

Kazuo Onuma 小沼 一雄

Research Projects

Research Products

Co-Researchers

Development of next-generation dental implant that regenerate periodontal tissue through phase transformation of amorphous calcium phosphate

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of Semi-crystalline Apatite Amorphous Complexes with Cell Recognition Functions and Their Application to Large Area Caries RepairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research on the development of periodontal tissue regenerative implants using titanium-binding proteins and cytokines

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Root-caries repair agent developed using reverse phase transformation from apatite to octacalcium phosphatePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Artificial enamel induced by phase transformation of amorphous nanoparticlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rapid regeneration of artificial enamel using laser-assisted biomineralization: With and without mesoscale hierarchy in hydroxyapatite rods2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic effect of FGF-2 and TGF-β1 on the mineralization of human umbilical cord perivascular cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cementum is key to periodontal tissue regeneration: A review on apatite microstructures for creation of novel cementum‐based dental implants2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Repurposing MDZ as a tool for tissue regeneration in dental cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coherent surface structure induces unique epitaxial overgrowth of metastable octacalcium phosphate on stable hydroxyapatite at critical fluoride concentration2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New insights into bioactivity of ceria-stabilized zirconia: Direct bonding to bone-like hydroxyapatite at nanoscale2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential for drug repositioning of midazolam for dentin regeneration.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in metastable calcium phosphate solution2019

Author(s)

Journal Title

Data Source

[Journal Article] Particle-size-dependent octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in calcium phosphate solution2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Octacalcium phosphate overgrowth on β-tricalcium phosphate substrate in metastable calcium phosphate solution2018

Onuma Kazuo 小沼一雄

Kazuo Onuma 小沼一雄