Motojima Fumihiro 元島史尋

… Alternative Names

MOTOJIMA Fumihiro 元島史尋

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Researcher Number	70372464
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2017: 富山県立大学, 工学部, 研究員 2009 – 2012: 京都産業大学, 総合生命科学部, 助教 2010: Tokyo Institute of Technology, 総合生命科学部, 助教 2007 – 2009: Tokyo Institute of Technology, 資源化学研究所, 助教 2005 – 2006: 東京工業大学, 資源化学研究所, 助手
Review Section/Research Field	Principal Investigator Structural biochemistry / Science and Engineering / Biophysics / Functional biochemistry Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 分子シャペロン / フォールディング / GroES / GroEL / 疎水性 / アンフォールディング / シャペロニン / 変性 / 1分子観察 / BFP … More / 蛍光anisotropy / 疎水性相互作用 / 揺らぎ / タンパク質 / リボソームサブユニット / リボソーム / Hsp90 / HtpG / 変性とフォールディング / クロスリンカー … More Except Principal Investigator 分子シャペロン / おれたたみ / プロテアーゼ / FtsH / C1pB / GroES / ClpB / DafA / DnaK / GroEL / シャペロニン / シャペロン Less

The elucidation of the folding acceleration mechanism of prokaryotic and eukaryotic chaperoninsPrincipal Investigator
- Principal Investigator
  
  Motojima Fumihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Toyama Prefectural University
シャペロニン援助フォールディングにおけるタンパク質の揺らぎ制御の解析Principal Investigator
- Principal Investigator
  
  元島史尋
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto Sangyo University
Functional analysis of E. coli Hsp90 (HtpG) to ribosome biogenesisPrincipal Investigator
- Principal Investigator
  
  MOTOJIMA Fumihiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo Institute of Technology
Protein handling by molecular chaperones
- Principal Investigator
  
  YOSHIDA Masasuke
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Sangyo University
  Tokyo Institute of Technology
Analysis on protein folding in restricted chaperonin cage by using photocleavable cross-linkerPrincipal Investigator
- Principal Investigator
  
  MOTOJIMA Fumihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Tokyo Institute of Technology
GroEL三者複合体の新規安定化中間体によるフォールディング促進機構の解析Principal Investigator
- Principal Investigator
  
  元島史尋
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Institute of Technology

All 2018 2017 2016 2015 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Physicochemical properties of the mammalian molecular chaperone HSP602018
- Author(s)
  Ishida, R. Okamoto, T. Motojima, F. Kubota, H. Takahashi, H. Tanabe, M. Oka, T. Kitamura, A. Kinjo, M. Yoshida, M. Otaka, M. Grave, E. Itoh, H.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 2 Pages: 489-489
- DOI
  10.3390/ijms19020489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06983
[Journal Article] Rapid Electrophoretic Staining and Destaining of Polyacrylamide Gels2018
- Author(s)
  Motojima, F.
- Journal Title
  
  Methods and Protocols
  
  Volume: 1 Issue: 2 Pages: 13-13
- DOI
  10.3390/mps1020013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06983
[Journal Article] Tethering effect by which improves protein folding in the chaperonin cage2016
- Author(s)
  元島　史尋
- Journal Title
  
  生化学
  
  Volume: 88 Issue: 6 Pages: 791-794
- DOI
  10.14952/SEIKAGAKU.2016.880791
- NAID
  40021054430
- ISSN
  0037-1017
- Year and Date
  2016-12-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K06983
[Journal Article] Productive folding of a tethered protein in the chaperonin GroEL-GroES cage2015
- Author(s)
  Fumihiro Motojima and Masasuke Yoshida
- Journal Title
  
  Biochemical and Biophysical Research Communication
  
  Volume: 466 Issue: 1 Pages: 72-75
- DOI
  10.1016/j.bbrc.2015.08.108
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06983
[Journal Article] FTIR study of primate color visual pigments2015
- Author(s)
  K. Katayama, H. Kandori
- Journal Title
  
  BIOPHYSICS
  
  Volume: 11 Issue: 0 Pages: 61-66
- DOI
  10.2142/biophysics.11.61
- NAID
  130004940814
- ISSN
  1349-2942
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-25620011, KAKENHI-PROJECT-15K06983
[Journal Article] Revisiting the contribution of negative charges on the chaperonin cage wall to the acceleration of protein folding2012
- Author(s)
  Motojima, F., Motojima-Miyazaki, Y., and Yoshida, M.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Issue: 39 Pages: 15740-15745
- DOI
  10.1073/pnas.1204547109
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23107728
[Journal Article] Revisiting the contribution of negative charges on the chaperonin cage wall to the acceleration of protein folding2012
- Author(s)
  Motojima F, Motojima-Miyazaki Y, Yoshida M
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109(39) Pages: 15740-5
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Polypeptide in the chaperonin cage partly protrudes out and then folds inside or escapes outside.2011
- Author(s)
  Motojima F, Yoshida M.
- Journal Title
  
  EMBO J.
  
  Volume: 29 Pages: 4008-4019
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Ribosomal protein L2 associates with E.coli HtpG and activates its ATPase activity.2011
- Author(s)
  Motojima-Miyazaki Y, Yoshida M, Motojima F.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 17 Pages: 241-245
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Polypeptide in the chaperonin cage partly protrudes out and then folds inside or escapes outside2010
- Author(s)
  Motojima F, Yoshida M
- Journal Title
  
  EMBO J
  
  Volume: 29 Pages: 4008-19
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20959808
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Ribosomal protein L2 associates with E.coli HtpG and activates its ATPase activity.2010
- Author(s)
  Motojima-Miyazaki Y, Yoshida M, Motojima F.
- Journal Title
  
  Biochem Biophys Res Commun. 400(2)
  
  Pages: 241-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770107
[Journal Article] Ribosomal protein L2 associates with E.coli HtpG and activates its ATPase activity2010
- Author(s)
  Motojima-Miyazaki Y, Yoshida M, Motojima F.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 400 Pages: 241-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770107
[Journal Article] Ribosomal protein L2 associates with E. coli HtpG and activates its ATPase activity2010
- Author(s)
  Motojima-Miyazaki Y, Yoshida M, Motojima F
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 241-5
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20727857
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Determination of the number of active GroES subunits in the fused heptamer GroES required for interactions with GroEL2008
- Author(s)
  Nojima, T., Murayama, S., Yoshida, M., Motojima, F.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 18385-18392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770127
[Journal Article] Determination of the Number of Active GroES Subunits in the Fused Heptamer GroES Reauired for Interactions with GroEL2008
- Author(s)
  Nojima T, Murayama S, Yoshida M, Motojima F
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 18385-92
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Determination of the Number of Active GroES Subunits in the Fused Heptamer GroES Required for Interactions with GroEL2008
- Author(s)
  Nojima T, Murayama S, Yoshida M, Motojima F.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 18385-18392
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Determination of the Number of Active GroES Subunits in the Fused Heptamer GroES Required for Interactions with GroEL2008
- Author(s)
  Nojima T, Murayama S, Yoshida M, Motojima F
- Journal Title
  
  J. Biol. Chem
  
  Volume: 283 Pages: 18385-92
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/18430731
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058004
[Journal Article] Structural Stability of Covalently Linked GroES Heptamer : Advantages in the Formation of Oligomeric Structure.2007
- Author(s)
  Sakane I, Hongo K, Motojima F, Murayama S, Mizobata T, Kawata Y
- Journal Title
  
  J. Mol. Biol. 367(4)
  
  Pages: 1171-1185
- Data Source
  KAKENHI-PROJECT-17770108
[Presentation] シャペロニンのアンフォールディング作用によるフォールディング促進効果2017
- Author(s)
  元島史尋、吉田賢右
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15K06983
[Presentation] How chaperonins fold proteins2015
- Author(s)
  元島史尋
- Organizer
  日本農芸化学会中部・関西支部合同大会
- Place of Presentation
  富山県立大学
- Year and Date
  2015-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K06983
[Presentation] シャペロニン空洞内フォールディングにおける疎水性相互作用の役割2015
- Author(s)
  元島史尋、吉田賢右
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K06983
[Presentation] "Football" with tethered polypeptide; renovation of chaperonin mechanism2012
- Author(s)
  M. Yoshida, T. Ando, D. Yamamoto, F. Motojima
- Organizer
  EMBL symposium
- Place of Presentation
  Heiderburg, Germany
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] シャペロニンがkinetically-trapped stateを回避しつつタンパク質をフォールドするメカニズム2012
- Author(s)
  元島史尋、元島（宮崎）優子、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] 大腸菌Hsp90（HtpG）の基質タンパク質のスクリーニング2012
- Author(s)
  元島（宮崎）優子、元島史尋、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] The conformational restriction of denatured protein encapsulated in the chaperonin cage.2012
- Author(s)
  元島史尋、元島（宮崎）優子、吉田賢右
- Organizer
  日本生物物理学会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] シャペロニン空洞内に閉じ込めたタンパク質の熱変性2012
- Author(s)
  藤井克弥、新谷大基、Daniel Xu、元島史尋、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] Chaperonin changes protein folding by regulation of hydrophobic residues2012
- Author(s)
  Fumihiro Motojima, Yuko Motojima-Miyazaki, Masasuke Yoshida
- Organizer
  The 5^<th> International Symposium Molecular Science of Fluctuations toward Biological Functions
- Place of Presentation
  東大寺文化会館(奈良県)(招待講演)
- Year and Date
  2012-01-07
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] Split luciferaseのシャペロニンによるフォールディング2012
- Author(s)
  田中翔太、元島（宮崎）優子、元島史尋、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] The interaction with the chaperonin cage changes the folding pathway of blue fluorescent protein (BFP)2011
- Author(s)
  元島史尋、吉田賢右
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] Chaperonin changes the heat capacity and pathway of BFP folding2011
- Author(s)
  元島史尋、元島(宮崎)優子、吉田賢右
- Organizer
  第49回日本生物物理学会年会
- Place of Presentation
  兵庫県立大学・姫路書写キャンパス(兵庫県)
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PUBLICLY-23107728
[Presentation] Tethering mechanism of chaperonin2011
- Author(s)
  Motojima F, Motojima-Miyazaki Y, Tanaka S, Yoshida M
- Organizer
  Cold Spring Harbor at Suzhou
- Place of Presentation
  China
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] Tethering mechanism of chaperonin2011
- Author(s)
  Motojima F, Motojima-Miyazaki Y, Tanaka S, Yoshida M
- Organizer
  Cold Spring Harbor at Suzhou
- Place of Presentation
  中国蘇州(招待講演)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] Fold or escape; fates of substrate polypeptide in the critical GroEL/GroES intermediate2010
- Author(s)
  Motojima F, Yoshida M
- Organizer
  Cold Spring Harbor Meeting
- Place of Presentation
  USA
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] E.coli HtpG specifically associates with ribosomal protein L2 and DnaK to form a ternary complex.2010
- Author(s)
  元島(宮崎)優子、元島史尋、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21770107
[Presentation] Polypeptide in the chaperonin cage partly protrudes out and then folds inside or escapes outside.2010
- Author(s)
  Yoshida M., Motojima F.
- Organizer
  The 3^<rd> International Symposium on Protein Community
- Place of Presentation
  奈良ホテル日航
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] The folding pathway of blue fluorescent protein in spontaneous and chaperonin-assisted folding2010
- Author(s)
  Motojima F, Yoshida M
- Organizer
  FASEB SRC, Protein folding in the cell
- Place of Presentation
  Saxtons River, Vermont. USA
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] Polypeptide in the chaperonin cage partly protrudes out and then folds inside or escapes outside2010
- Author(s)
  Motojima F, Yoshida M
- Organizer
  ISCP Nara
- Place of Presentation
  Nara, Japan
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] Ribosome protein L2 is a client protein for E. coli HtpG2009
- Author(s)
  Miyazaki, Y., Motojima, F., Yoshida, M.
- Organizer
  日本生化学会82回年会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] リボソームタンパク質L2は大腸菌Hsp90(HtpG)の基質タンパク質である2009
- Author(s)
  元島(宮崎)優子、元島史尋、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21770107
[Presentation] シャペロニンGroELの新しいモデル2009
- Author(s)
  元島史尋、吉田賢右
- Organizer
  生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] The ATPase cycleof chaperonin gives another chance of the assisted folding to the escaped protein from the chaperonin cage2009
- Author(s)
  Motojima, F., Yoshida, M.
- Organizer
  日本生化学会82回年会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] 変性タンパク質がGroEL.に結合した状態がシャペロニン依存的フォールディングにおける律速中間体である2008
- Author(s)
  Motojima, F., Yoshida, M
- Organizer
  日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] GroEL/ES-assisted folding of bfp starts from an extended state and is faster than free folding2008
- Author(s)
  Motojima F, Yoshida M
- Organizer
  Cold Spring Harbor Meeting
- Place of Presentation
  USA
- Year and Date
  2008-05-02
- Data Source
  KAKENHI-PLANNED-19058004
[Presentation] 変性タンパク質がGroELに結合した状態がシャペロニン依存的フォールディングにおける律速中間体である2008
- Author(s)
  Motojima, F., Yoshida, M.
- Organizer
  日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19770127
[Presentation] Blue fluorescent protein folds from unfolded state by chaperonin2008
- Author(s)
  Motojima, F., Yoshida, M.
- Organizer
  米国コールドスプリングハーバー会議
- Place of Presentation
  米国コールドスプリングハーバー
- Year and Date
  2008-04-30
- Data Source
  KAKENHI-PROJECT-19770127
[Presentation] 分子シャペロンGroEL/ESはBFPのフォールディング経路を速度論的にだけでなく構造的にも変化させる2007
- Author(s)
  Motojima, F, . Yoshida, M.
- Organizer
  日本生物物理学会
- Place of Presentation
  ペシフィコ横浜
- Year and Date
  2007-12-22
- Data Source
  KAKENHI-PROJECT-19770127
[Presentation] 分子シャペロンGroEL/ESはBFPのフォールディング経路を速度論的にだけでなく構造的にも変化させる2007
- Author(s)
  Motojima, F., Yoshida, M
- Organizer
  日本生物物理学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-22
- Data Source
  KAKENHI-PROJECT-19770127

1. YOSHIDA Masasuke (90049073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
2. WATANABE Yohei (40411839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NUREKI Satoshi (10272460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Motojima Fumihiro 元島 史尋

MOTOJIMA Fumihiro 元島 史尋

Research Projects

Research Products

Co-Researchers

The elucidation of the folding acceleration mechanism of prokaryotic and eukaryotic chaperoninsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シャペロニン援助フォールディングにおけるタンパク質の揺らぎ制御の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of E. coli Hsp90 (HtpG) to ribosome biogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein handling by molecular chaperones

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis on protein folding in restricted chaperonin cage by using photocleavable cross-linkerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GroEL三者複合体の新規安定化中間体によるフォールディング促進機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Physicochemical properties of the mammalian molecular chaperone HSP602018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid Electrophoretic Staining and Destaining of Polyacrylamide Gels2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tethering effect by which improves protein folding in the chaperonin cage2016

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Productive folding of a tethered protein in the chaperonin GroEL-GroES cage2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FTIR study of primate color visual pigments2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Revisiting the contribution of negative charges on the chaperonin cage wall to the acceleration of protein folding2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Revisiting the contribution of negative charges on the chaperonin cage wall to the acceleration of protein folding2012

Author(s)

Motojima Fumihiro 元島史尋

MOTOJIMA Fumihiro 元島史尋