Suzuki Hiroyuki 鈴木裕之

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SUZUKI Hiroyuki 鈴木裕之

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Researcher Number	70375509
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東北大学, 医学系研究科, 准教授 2013 – 2020: 筑波大学, 医学医療系, 准教授 2011: 筑波大学, 医学医療系, 助教 2007 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 助教 2006: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Research Associate, 大学院人間総合科学研究科, 助手 2005: 筑波大学, 大学院・人間総合科学研究科, 助手
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 49030:Experimental pathology-related / General medical chemistry Except Principal Investigator General medical chemistry / Tumor biology
Keywords	Principal Investigator THG-1 / 扁平上皮がん / TSC22D4 / Ras / EGF / Tsc-22 / 分子標的治療 / がん / がん遺伝子 / 癌 … More / 転写因子 / 幹細胞 / c-Myc / がん治療薬 / タンパク質間相互作用 / 炎症 / Squamous cell carcinoma / NRBP1 / TRAF6 / Interleukin-1 / TSC22D4/THG-1 / TSC-22 / 細胞老化 / beta-Catenin / SALL4 / リン酸化 / CD44 / THF-1 / THG-1 ノックアウトマウス / THG-1 / TSC22D4 / ペプチド / タンパク質相互作用 / 転移 / 細胞増殖 / 扁平上皮 / Tsc-22 family / MAPK / 重層扁平上皮 / ERas / Oct-4 / p21 / Eras / Oct4 … More Except Principal Investigator Herp2 / Id1 / CGI-128 / E2-2 / Smad / TGF-beta / Embryonic lethality / Angiogenesis / 胎盤 / BMP / 転写因子 / 胎生死 / 血管新生 / Nrf2 / Keap-1 / がん幹細胞 / 浸潤 / がん細胞代謝 / 扁平上皮癌 / RAS/MAPK経路 / THG-1 / 肺がん / 子宮頸がん / 食道がん / 扁平上皮がん Less

新規がん遺伝子THG-1の生体機能の解明と分子診断・治療法の開発Principal Investigator
- Principal Investigator
  
  鈴木裕之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tohoku University
Role of THG-1 in squamous cell carcinoma development and its application to cancer therapyPrincipal Investigator
- Principal Investigator
  
  SUZUKI Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tohoku University
  University of Tsukuba
Roles of THG-1 in squamous cell carcinoma developmentPrincipal Investigator
- Principal Investigator
  
  Suzuki Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Tsukuba
Roles of Tsc-22 family proteins in cell proliferation, differentiation and tumorigenesisPrincipal Investigator
- Principal Investigator
  
  Suzuki Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Tsukuba
Tumorigenic activity of tissue-specific oncogene THG-1
- Principal Investigator
  
  KATO Mitsuyasu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  University of Tsukuba
Roles of THG-1 on cellular proliferation, differentiation and tumorgenesisPrincipal Investigator
- Principal Investigator
  
  SUZUKI Hiroyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Tsukuba
Regulation of stem cell proliferation by Tsc-22Principal Investigator
- Principal Investigator
  
  SUZUKI Hiroyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
新規c-Myc結合タンパク質による幹細胞の増殖、分化制御機構Principal Investigator
- Principal Investigator
  
  鈴木裕之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
Regulation of endothelial cell activation by TGF-β family signaling
- Principal Investigator
  
  ITOH Susumu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba

[Journal Article] Development of a Novel Anti-CD44 Variant 5 Monoclonal Antibody C44Mab-3 for Multiple Applications against Pancreatic Carcinomas2023
- Author(s)
  Kudo Yuma、Suzuki Hiroyuki、Tanaka Tomohiro、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  Antibodies
  
  Volume: 12 Issue: 2 Pages: 31-31
- DOI
  10.3390/antib12020031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06995, KAKENHI-PROJECT-21K07168
[Journal Article] Promotion of squamous cell carcinoma tumorigenesis by oncogene‐mediated THG‐1/TSC22D4 phosphorylation2023
- Author(s)
  Goto Nohara、Suzuki Hiroyuki、Zheng Ling、Okano Yasuhito、Okita Yukari、Watanabe Yukihide、Kato Yukinari、Kato Mitsuyasu
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 10 Pages: 3972-3983
- DOI
  10.1111/cas.15934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15596, KAKENHI-PROJECT-22K06995, KAKENHI-PROJECT-20K20597
[Journal Article] A Novel Anti-CD44 Variant 3 Monoclonal Antibody C44Mab-6 Was Established for Multiple Applications2023
- Author(s)
  Suzuki Hiroyuki、Kitamura Kaishi、Goto Nohara、Ishikawa Kenichiro、Ouchida Tsunenori、Tanaka Tomohiro、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 9 Pages: 8411-8411
- DOI
  10.3390/ijms24098411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06995, KAKENHI-PROJECT-21K07168
[Journal Article] Roles of Podoplanin in Malignant Progression of Tumor2022
- Author(s)
  Suzuki Hiroyuki、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 3 Pages: 575-575
- DOI
  10.3390/cells11030575
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07473
[Journal Article] Antitumor Activity of an Anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma2022
- Author(s)
  Tateyama Nami、Suzuki Hiroyuki、Ohishi Tomokazu、Asano Teizo、Tanaka Tomohiro、Mizuno Takuya、Yoshikawa Takeo、Kawada Manabu、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 11 Pages: 2494-2494
- DOI
  10.3390/pharmaceutics14112494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07168, KAKENHI-PROJECT-22K06783, KAKENHI-PROJECT-22K06995, KAKENHI-PROJECT-22K07224
[Journal Article] Development of a Novel Anti-CD44 Monoclonal Antibody for Multiple Applications against Esophageal Squamous Cell Carcinomas2022
- Author(s)
  Goto Nohara、Suzuki Hiroyuki、Tanaka Tomohiro、Asano Teizo、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 10 Pages: 5535-5535
- DOI
  10.3390/ijms23105535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06995
[Journal Article] Epitope Mapping of the Anti-CD44 Monoclonal Antibody (C<sub>44</sub>Mab-46) Using Alanine-Scanning Mutagenesis and Surface Plasmon Resonance2021
- Author(s)
  Takei Junko、Asano Teizo、Suzuki Hiroyuki、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 40 Issue: 5 Pages: 219-226
- DOI
  10.1089/mab.2021.0028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07473, KAKENHI-PROJECT-19K07705
[Journal Article] Epitope Mapping of a Cancer-Specific Anti-Podocalyxin Monoclonal Antibody (PcMab-60) Using Enzyme-Linked Immunosorbent Assay and Surface Plasmon Resonance2021
- Author(s)
  Asano Teizo、Suzuki Hiroyuki、Kaneko Mika K.、Kato Yukinari
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 40 Issue: 5 Pages: 227-232
- DOI
  10.1089/mab.2021.0030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07473
[Journal Article] Glycoprotein non-metastatic melanoma protein B functions with growth factor signaling to induce tumorigenesis through its serine phosphorylation2021
- Author(s)
  Wang Chen、Okita Yukari、Zheng Ling、Shinkai Yasuhiro、Manevich Lev、Chin Jas M.、Kimura Tomokazu、Suzuki Hiroyuki、Kumagai Yoshito、Kato Mitsuyasu
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 10 Pages: 4187-4197
- DOI
  10.1111/cas.15090
- NAID
  120007178942
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07473, KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20K20597
[Journal Article] THG-1 suppresses SALL4 degradation to induce stemness genes and tumorsphere formation through antagonizing NRBP1 in squamous cell carcinoma cells.2020
- Author(s)
  Hwang J, Haque MA, Suzuki H, Dijke PT, Kato M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 523 Issue: 2 Pages: 307-314
- DOI
  10.1016/j.bbrc.2019.11.149
- NAID
  120007127582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07473
[Journal Article] Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of JUNB.2020
- Author(s)
  Zhang X, Koga N, Suzuki H, Kato M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 522 Issue: 4 Pages: 897-902
- DOI
  10.1016/j.bbrc.2019.11.145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07473
[Journal Article] Generation of non-standard macrocyclic peptides specifically binding TSC-22 homologous gene-12019
- Author(s)
  Tran STP, Hipolito CJ, Suzuki H, Xie R, Kim Tuyen HD, Dijke PT, Terasaka N, Goto Y, Suga H, Kato M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 516 Issue: 2 Pages: 445-450
- DOI
  10.1016/j.bbrc.2019.06.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07473, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762
[Journal Article] Stereodivergent Synthesis of Bispyrrolidinoindoline Alkaloidal Scaffolds and Generation of a Lead Candidate with Stereospecific Antiproliferative Activity2019
- Author(s)
  Wada Mitsuhiro、Suzuki Hiroyuki、Kato Mitsuyasu、Oikawa Hideaki、Tsubouchi Akira、Oguri Hiroki
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 10 Pages: 1273-1281
- DOI
  10.1002/cbic.201800815
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04388, KAKENHI-PROJECT-16K08706, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H02847
[Journal Article] Glycoprotein nmb is exposed on the surface of dormant breast cancer cells and induces stem cell-like properties2018
- Author(s)
  Chen Chen、Okita Yukari、Watanabe Yukihide、Abe Fumie、Fikry Muhammad Ali、Ichikawa Yumu、Suzuki Hiroyuki、Shibuya Akira、Kato Mitsuyasu
- Journal Title
  
  Cancer Research
  
  Volume: 78 Issue: 22 Pages: 6424-6435
- DOI
  10.1158/0008-5472.can-18-0599
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-16K08706, KAKENHI-PROJECT-17K14981
[Journal Article] The possible repositioning of an oral anti-arthritic drug, auranofin, for Nrf2-activating therapy: The demonstration of Nrf2-dependent anti-oxidative action using a zebrafish model.2018
- Author(s)
  Fuse Y,Endo Y, Araoi S, Daitoku H, Suzuki H, Kato M, Kobayashi M.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 115 Pages: 405-411
- DOI
  10.1016/j.freeradbiomed.2017.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08706, KAKENHI-PROJECT-17J04162, KAKENHI-PROJECT-26520101
[Journal Article] Regulation of c-MYC transcriptional activity by transforming growth factor-beta 1-stimulated clone 22.2018
- Author(s)
  Zheng L, Suzuki H, Nakajo Y, Nakano A, Kato M.
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Issue: 2 Pages: 395-402
- DOI
  10.1111/cas.13466
- NAID
  120007134448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08706
[Journal Article] The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB2017
- Author(s)
  Yukari Okita, Minori Kimura, Rudy Xie, Chen Chen, Larina Tzu-Wei Shen, Yurika Kojima, Hiroyuki Suzuki, Masafumi Muratani, Masao Saitoh, Kentaro Semba, Carl-Henrik Heldin, Mitsuyasu Kato
- Journal Title
  
  Science Signaling
  
  Volume: 10 Issue: 474 Pages: 11-11
- DOI
  10.1126/scisignal.aak9397
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19070, KAKENHI-PROJECT-16K08706, KAKENHI-PUBLICLY-15H01343, KAKENHI-PROJECT-15H05576
[Journal Article] β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.2016
- Author(s)
  Ahmed M. Abdellatif, Hisashi Oishi , Takahiro Itagaki, Yunshin Jung, Hossam H. Shawki, Yukari Okita, Yoshikazu Hasegawa, Hiroyuki Suzuki, Salah E. El-Morsy, Mesbah A. El-Sayed, Mahmoud B. Shoaib, Fumihiro Sugiyama, Satoru Takahashi
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 2 Pages: e0150010-e0150010
- DOI
  10.1371/journal.pone.0150010
- NAID
  120007129599
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-26460356
[Journal Article] Transforming growth factor-&βinduces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.2013
- Author(s)
  Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 28 Pages: 20658-20667
- DOI
  10.1074/jbc.m113.450478
- NAID
  120007136878
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059
[Journal Article] Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation2011
- Author(s)
  Kaneko MK, Tian W, Takano S, Suzuki H, Sawa Y, Hozumi Y, Goto K, Yamazaki K, Kitanaka C, Kato Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 608-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790374
[Journal Article] Protein kinase C-dependent upregulation of miR-203 induces the differe ntiation of human keratinocytes2010
- Author(s)
  Sonkoly E, Wei T, Lorie EP, Suzuki H, Kato. M, Torma H, Stahle M, Pivarcsi A
- Journal Title
  
  J Invest Dermatol 130
  
  Pages: 124-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] TGF-β, 間接リウマチ2010
- Author(s)
  鈴木裕之、青山知恵、加藤光保
- Journal Title
  
  日本臨床
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] TGF-β2010
- Author(s)
  鈴木裕之、青山知恵、加藤光保
- Journal Title
  
  間接リウマチ(日本臨床社) (印刷中)
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] Protein kinase C-dependent upregulation of miR-203 induces the differentiation of human keratinocytes.2010
- Author(s)
  Sonkoly E, Wei T, Lorie EP, Suzuki H, Kato. M, Torma H, Stahle M, Pivarcsi A
- Journal Title
  
  J Invest Dermatol. 130
  
  Pages: 124-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals2008
- Author(s)
  Suzuki T, Tsutsumi A, Suzuki H, Suzuki E, Sugihara M, Muraki Y, Hayashi T, Chino Y, Goto D, Matsumoto I, Ito S, Miyazawa K, Sumida T
- Journal Title
  
  Mod Rheumatol 18
  
  Pages: 472-479
- NAID
  10024374213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] TGF-βシグナル伝達と癌治療2008
- Author(s)
  鈴木裕之、中条友香、加藤光保
- Journal Title
  
  がんの分子標的治療(南山道)
  
  Pages: 132-139
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] Roles of mono-ubiquitinated Smad4 in the formation of Smad transcriptional complexes2008
- Author(s)
  Wang B, Suzuki H (correspondin author), Kato M.
- Journal Title
  
  Biochem Biophys Res Commun 376
  
  Pages: 288-292
- NAID
  120007138520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] TGF-βシグナル伝達とがん治療2008
- Author(s)
  鈴木裕之、中条友香、加藤光保
- Journal Title
  
  がんの分子標的治療(南山堂)
  
  Pages: 132-139
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] Roles of mono-ubiquitinated Smad4 in the formation of Smad transcriptional complexes.2008
- Author(s)
  Wang B, Suzuki H (corresponding author), Kato M.
- Journal Title
  
  Biochem Biophys Res Commun. 376
  
  Pages: 288-292
- NAID
  120007138520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals.2008
- Author(s)
  Suzuki T, Tsutsumi A, Suzuki H, Suzuki E, Sugihara M, Muraki Y, Hayashi T, Chino Y, Goto D, Matsumoto I, Ito S, Miyazawa K, Sumida T
- Journal Title
  
  Mod Rheumatol 18
  
  Pages: 472-479
- NAID
  10024374213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790220
[Journal Article] Induction of podoplanin by transforming growth factor-beta in human fibrosarcoma.2008
- Author(s)
  Suzuki H, Kato Y, Kaneko MK, Okita Y, Narimatsu H Kato M
- Journal Title
  
  FEBS letters 582
  
  Pages: 341-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790190
[Journal Article] Suppression of MafA dependent transcription by transforming growth factor-beta signaling.2007
- Author(s)
  Matsumura H, Kudo T, Harada A, Esaki R, Suzuki H, Kato.M and Takahashi.S
- Journal Title
  
  Biochem Biophys Res Commun. 364
  
  Pages: 151-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790190
[Journal Article] Suppression of keratinocyte stratification by a dominant negative JunB mutant without blocking cell proliferation.2007
- Author(s)
  Ikebe D, Wang B, Suzuki H, Kato M.
- Journal Title
  
  Genes Cells 12
  
  Pages: 197-207
- Data Source
  KAKENHI-PROJECT-18790190
[Presentation] Role of THG-1 in inflammatory responses of squamous cell carcinoma2023
- Author(s)
  Yasuhito Okano, Hiroyuki Suzuki, Yukihide Watanabe, Mohammed Abdelaziz, Lev Manevich, Kunio Kawanishi, Shin Matsumoto, Nohara Goto, Ling Zheng, Yukari Okita, Masahiro Nakayama, Yoshihide Shima, Keiji Tabuchi, and Mitsuyasu Kato
- Organizer
  TGF-beta meeting, Uppsala
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06995
[Presentation] Development of a Novel Anti-CD44 Monoclonal Antibody for Esophageal Squamous Cell Carcinomas2022
- Author(s)
  鈴木裕之、後藤のはら、田中智大、金子美華、加藤幸成
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06995
[Presentation] Regulation of CD44 splicing by THG-1 / TSC22D42022
- Author(s)
  後藤のはら、鈴木裕之、加藤光保
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06995
[Presentation] Defucosylated Mouse-Dog Chimeric Anti-EGFR Antibody Exerts Antitumor Activities in Mouse Xenograft Models of Canine Tumors2022
- Author(s)
  鈴木裕之、李冠傑、浅野禎三、田中智大、金子美華、加藤幸成
- Organizer
  第96回日本薬理学会年会・第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06995
[Presentation] Roles of THG-1/Tsc22D4 in squamous cell carcinoma development2021
- Author(s)
  Suzuki Hiroyuki and Kato Mitsuyasu
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07473
[Presentation] Screening of protein-protein interaction inhibitors between TSC-22 homologous gene-1 and its interacting proteins2021
- Author(s)
  Suzuki Hiroyuki
- Organizer
  TGF-beta meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07473
[Presentation] Regulation of cellular senescence by THG-1/TSC22D42020
- Author(s)
  Suzuki Hiroyuki and Kato Mitsuyasu
- Organizer
  第79回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07473
[Presentation] THG-1 overexpression stabilizes β-catenin via antagonizing NRBP1 in esophageal squamous cell carcinoma2020
- Author(s)
  Hwang Jongchan, Suzuki Hiroyuki and Kato Mitsuyasu
- Organizer
  第79回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07473
[Presentation] Oncogenic functions of TGFβ-stimulated clone-22 families2019
- Author(s)
  Hiroyuki Suzuki
- Organizer
  STINT Special Symposium on the Sweden-Japan 150 Anniversary Grant
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] Regulation of c-MYC transcriptional activity by transforming growth factor-beta 1 stimulated clone 222019
- Author(s)
  Suzuki Hiroyuki and Kato Mitsuyasu
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07473
[Presentation] Screening of macrocyclic peptide against CD442019
- Author(s)
  Goto Nohara, HIPOLITO CHRISTOPHER, Suzuki Hiroyuk and Kato Mitsuyasu
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07473
[Presentation] THG-1, a novel oncogene in tumor angiogenesis2018
- Author(s)
  Ling Zheng, 鈴木裕之,加藤光保
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] Oncogenic fuinctions of THG-1/Tsc22D4 in squamous cell carcinoma development2018
- Author(s)
  鈴木裕之, 加藤光保
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] Roles of THG-1/Tsc22D4 and its binding proteins in tumor development2017
- Author(s)
  鈴木裕之　加藤光保
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] THG-1/Tsc22D4の腫瘍化における役割2017
- Author(s)
  三浦万侑花　鈴木裕之　加藤光保
- Organizer
  第106回　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] 乳がんの発生・進展におけるGPNMBの役割2017
- Author(s)
  沖田結花里　鈴木裕之　加藤光保
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] THG-1はHIF-1alphaを安定化して腫瘍の血管新生を促進する2017
- Author(s)
  テイレイ　鈴木裕之　加藤光保
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] THG-1/Tsc22D4の腫瘍化における役割2017
- Author(s)
  三浦万侑花　鈴木裕之　加藤光保
- Organizer
  第106回日本病理学会総会
- Place of Presentation
  京王プラザホテル・東京都・新宿区
- Year and Date
  2017-04-27
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] Roles of THG-1/TSC22D4 in squamous cell carcinoma progression2017
- Author(s)
  鈴木裕之　小沼雅世　加藤光保
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] 扁平上皮がんの病理発生2016
- Author(s)
  鈴木裕之　加藤光保
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター・宮城県・仙台市
- Year and Date
  2016-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] 新規がん遺伝子THG-1/Tsc22D4はHIF-1αの安定化を介して腫瘍の血管新生を促進する2016
- Author(s)
  テイレイ　鈴木裕之　加藤光保
- Organizer
  第39回分子生物学会年会
- Place of Presentation
  パシフィコ横浜・神奈川県・横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] 扁平上皮がんの病理発生2016
- Author(s)
  鈴木裕之
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台（仙台国際センター）
- Year and Date
  2016-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Roles of THG-1/Tsc22D4 in tumor development2016
- Author(s)
  鈴木裕之　加藤光保
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜・神奈川県・横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] Tsc-22ファミリータンパク質のがん進展における役割2016
- Author(s)
  鈴木裕之　小沼雅世　加藤光保
- Organizer
  第39回分子生物学会年会
- Place of Presentation
  パシフィコ横浜・神奈川県・横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08706
[Presentation] Roles of THG-1/Tsc22D4 in squamous cell carcinoma development2015
- Author(s)
  鈴木裕之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Roles of THG-1/Tsc22D4 in squamous cell carcinoma development2015
- Author(s)
  Hiroyuki Suzuki
- Organizer
  Tsukuba-UCI Science Partnership Conference 2015
- Place of Presentation
  California　（アメリカ）
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Tsc-22ファミリータンパク質の腫瘍化における役割2015
- Author(s)
  鈴木裕之
- Organizer
  第61回日本病理学会秋期特別総会
- Place of Presentation
  東京（東京大学）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Roles of THG-1/Tsc22D4 in squamous cell carcinoma development2015
- Author(s)
  Hiroyuki Suzuki
- Organizer
  TGF-beta meeting in Uppsala
- Place of Presentation
  Uppsala（スウェーデン）
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Hypoxia and oxidative stress resistance in squamous cell carcinoma2014
- Author(s)
  Hiroyuki Suzuki
- Organizer
  Annual meeting of Hypoxia
- Place of Presentation
  ジャカルタ
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] 細胞増殖、分化、がん化におけるTsc-22ファミリー分子の役割2013
- Author(s)
  鈴木裕之
- Organizer
  第32回　分子病理研究会
- Place of Presentation
  吉野
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Roles of Tsc-22 family proteins in tumorigenesis2013
- Author(s)
  鈴木裕之
- Organizer
  第72回　日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] 細胞増殖、分化、がん化におけるTsc-22ファミリー分子の役割2013
- Author(s)
  鈴木裕之
- Organizer
  第102回　日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] 細胞増殖、分化、癌化におけるTsc-22ファミリー分子の役割2013
- Author(s)
  鈴木裕之、加藤光保
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25640059
[Presentation] Roles of Tsc-22 family proteins in tumorigenesis2013
- Author(s)
  Hiroyuki Suzuki
- Organizer
  TGF-beta meeting in Uppsala
- Place of Presentation
  ウプサラ　スウェーデン
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Roles of THG-1/Tsc22D4 on cell proliferation, differentiation and tumorigenesis2011
- Author(s)
  Suzuki H Nakayama. Y and Kato M
- Organizer
  平成22年度「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  大津
- Year and Date
  2011-02-03
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] 細胞増殖、分化、癌化におけるTsc-22ファミリー分子の役割2011
- Author(s)
  鈴木裕之、加藤光保
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] 3次元再構築による大腸腺腫発生機序の解析2011
- Author(s)
  Inada. H Aoyama C Suzuki H and Kato M
- Organizer
  99^<th> Annual meeting of the Japanese Society of Pathology
- Place of Presentation
  Tokyo
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] Regulation of cellular proliferation by transforming growth factor-β stimulated clone 222011
- Author(s)
  Suzuki H, Nakano A, Harada T and Kato M
- Organizer
  99^<th> Annual meeting of the Japanese Society of Pathology
- Place of Presentation
  Tokyo
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] THG-1の腫瘍形成促進作用2011
- Author(s)
  Ito Y, Suzuki H and Kato M
- Organizer
  30^<th> Molecular pathology meeting
- Place of Presentation
  Okayama
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] Roles of Tsc-22 family members in cell proliferation, differentiation and tumorigenesis2011
- Author(s)
  Suzuki H and Kato M
- Organizer
  70^<th> Annual meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] 3次元再構築による大腸腺腫発生機序の解析2011
- Author(s)
  Inada H, Aoyama C, Suzuki H and Kato M
- Organizer
  30^<th> Molecular pathology meeting
- Place of Presentation
  Okayama
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] MafK induces EMT and promotes tumorigenic activities FASEB Summer Research Conferences2011
- Author(s)
  Okita Y, Suzuki H and Kato M
- Place of Presentation
  Pisa, Italy
- Year and Date
  2011-08-24
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] Roles of Tsc-22 family proteins in cell proliferation, differentiation and tumorigenesis2011
- Author(s)
  鈴木裕之、加藤光保
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] A novel EMT inducer MafK promotes tumorigenicity2011
- Author(s)
  Okita Y, Suzuki H and Kato M
- Organizer
  TGF-β meeting
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2011-08-18
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] Tsc-22 inhibits cellular proliferation through regulation of c-Myc and Oct42010
- Author(s)
  Suzuki H, Nakajo Y, Nakano A, Nakayama. Y, Kato M
- Organizer
  AACR/JCA Joint Conference
- Place of Presentation
  Waikoloa, Hawaii
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Tsc-22 inhibits cellular proliferation through regulation of c-Myc and Oct42010
- Author(s)
  Hiroyuki Suzuki, Akinobu Nakano, Mitsuyasu Kato
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] Tsc-22 inhibits cellular proliferation through regulation of c-Myc and Oct42010
- Author(s)
  Suzuki H, Nakano A and Kato M
- Organizer
  69^<th> Annual meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790374
[Presentation] Regulation of cellular proliferation by transforming growth factor-β stimulated clone 222009
- Author(s)
  Suzuki H, Nakano A, Kato M
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Promotion of colony dispersion and cell motility by cooperative action of TGF-β and EGF signaling2009
- Author(s)
  Suzuki H, Tozuka R, Kato M
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Promotion of colony dispersion and cell motility by cooperative action of TGF-βand EGF signaling2009
- Author(s)
  Suzuki H, Tozuka R, Kato M
- Organizer
  98th Annual meeting of the Japanese Society of Pathology
- Place of Presentation
  Oral in Japanese
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Regulation of cellular proliferation by transforming growth factor-b stimulated clone 222009
- Author(s)
  Suzuki H, Nakano A, Kato M
- Organizer
  68th Annual meeting
- Place of Presentation
  Japanese Cancer Association
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Differential regulation of c-Myc transcriptional activity by transforming growth factor-beta stimulated clone 222008
- Author(s)
  Hiroyuki Suzuki, Akinobu Nakano and Mitsuyasu Kato
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Differential regulation of c-Myc transcriptional activity by transforming growth factor-beta stimulated clone 222008
- Author(s)
  Hiroyuki Suzuki, Yuka Naka jo, Akindbu Nakano, Bei Wang, Kumiko Miki and Mitsuyasu Kato
- Organizer
  札幌がんセミナー国際シンポジウム
- Place of Presentation
  北海道大学
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-20790220
[Presentation] Differential regulation of c-Myc transcriptional activity by transforming growth factor-beta stimulated clone 222007
- Author(s)
  Hiroyuki, Suzuki, Akinobu, Nakano, Mitsuyasu, Kato
- Organizer
  日本癌学会総会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18790190
[Presentation] Tsc-22ファミリータンパク質の腫瘍化における役割
- Author(s)
  鈴木裕之
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] 細胞増殖、分化、がん化におけるTsc-22ファミリー分子の役割
- Author(s)
  鈴木裕之
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25460472
[Presentation] Roles of THG-1/Tsc22D4 in squamous cell carcinoma development
- Author(s)
  Hiroyuki Suzuki
- Organizer
  Joint International Symposium on TGF-β Family and Cancer
- Place of Presentation
  つくば市
- Year and Date
  2015-01-12 – 2015-01-13
- Invited
- Data Source
  KAKENHI-PROJECT-25460472
[]
[]

1. KATO Mitsuyasu (20194855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. ITOH Susumu (70223154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鄭齢 (70833565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 沖田結花里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 金子美華

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 本橋ほづみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 大栗博毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Hiroyuki 鈴木 裕之

SUZUKI Hiroyuki 鈴木 裕之

Research Projects

Research Products

Co-Researchers

新規がん遺伝子THG-1の生体機能の解明と分子診断・治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of THG-1 in squamous cell carcinoma development and its application to cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of THG-1 in squamous cell carcinoma developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of Tsc-22 family proteins in cell proliferation, differentiation and tumorigenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tumorigenic activity of tissue-specific oncogene THG-1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of THG-1 on cellular proliferation, differentiation and tumorgenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of stem cell proliferation by Tsc-22Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規c-Myc結合タンパク質による幹細胞の増殖、分化制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of endothelial cell activation by TGF-β family signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of a Novel Anti-CD44 Variant 5 Monoclonal Antibody C44Mab-3 for Multiple Applications against Pancreatic Carcinomas2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Promotion of squamous cell carcinoma tumorigenesis by oncogene‐mediated THG‐1/TSC22D4 phosphorylation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Novel Anti-CD44 Variant 3 Monoclonal Antibody C44Mab-6 Was Established for Multiple Applications2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of Podoplanin in Malignant Progression of Tumor2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antitumor Activity of an Anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma2022

Suzuki Hiroyuki 鈴木裕之

SUZUKI Hiroyuki 鈴木裕之