Ohge Hiroki 大毛宏喜

… Alternative Names

大毛宏喜オオゲヒロキ

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Researcher Number	70379874
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(医), 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 広島大学, 病院(医), 教授 2016 – 2017: 広島大学, 病院(医), 教授 2015: 広島大学, 大学病院(医), 教授 2015: 広島大学, 医学部, 教授 2013 – 2015: 広島大学, 大学病院, 教授 2012: 広島大学, その他の研究科, 教授
Review Section/Research Field	Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 56030:Urology-related / Basic Section 57080:Social dentistry-related / Applied pharmacology / Infectious disease medicine
Keywords	Except Principal Investigator 薬力学 / 薬物動態 / 感染症 / 臨床 / 精子運動能 / レトロトランスポゾン / TLR7/8 / 内在性ウイルス配列 / 口腔衛生管理 / 口腔内耐性菌 … More / 介護医療院 / 口腔ケア / 要介護 / 医療・介護関連肺炎 / 誤嚥性肺炎 / 専門的口腔衛生管理 / 非経口摂取 / 口腔 / 口腔衛生 / 要介護高齢者 / 薬剤耐性菌 / 薬剤耐性 / 抗芽胞作用 / 透過型電子顕微鏡 / 走査型電子顕微鏡 / Bacillus cereus / Bacillus subtilis / 電子顕微鏡 / 次亜塩素酸ナトリウム / 二酸化塩素 / 消毒薬 / 芽胞 Less

抗嫌気性菌薬療法の感染組織中動態・患者病態因子・薬剤耐性機構に基づく個別最適化
- Principal Investigator
  
  猪川和朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hiroshima University
ヒトゲノム内在性ウイルス配列によるX精子運動能制御の解明
- Principal Investigator
  
  林哲太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Hiroshima University
Understanding the distribution of resistant bacteria in the oral cavity and the impact of oral hygiene management by dentists on healthcare-associated pneumonia
- Principal Investigator
  
  Yoshikawa Mineka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Hiroshima University
Optimization of antimicrobial therapy based on integrated quantitative evaluation of physiological pharmacokinetics, disease pharmacodynamics and drug-resistance mechanisms
- Principal Investigator
  
  Ikawa Kazuro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hiroshima University
Optimization of antimicrobial therapy based on relation and interaction among drug, causative organism and host immunity
- Principal Investigator
  
  Ikawa Kazuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Hiroshima University
Study on the bactericidal effect of chlorine dioxide against bacterial spores.
- Principal Investigator
  
  Yamada Sakuo
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kawasaki Medical School

All 2023 2022 2020 2019 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Pharmacokinetics of cefmetazole in plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients scheduled for lower gastrointestinal surgery: Dosing considerations based on site-specific pharmacodynamic target attainment2023
- Author(s)
  Kaiki Yuki、Ohge Hiroki、Ikawa Kazuro、Uegami Shinnosuke、Watadani Yusuke、Shigemoto Norifumi、Hirano Toshinori、Yoshimura Kosuke、Kitagawa Hiroki、Morikawa Norifumi、Takahashi Shinya
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 29 Issue: 3 Pages: 309-315
- DOI
  10.1016/j.jiac.2022.12.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06767, KAKENHI-PROJECT-22K06723
[Journal Article] Pharmacokinetics of flomoxef in plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients undergoing lower gastrointestinal surgery: Dosing considerations based on site-specific pharmacodynamic target attainment2023
- Author(s)
  Hirano Toshinori、Ohge Hiroki、Ikawa Kazuro、Uegami Shinnosuke、Watadani Yusuke、Shigemoto Norifumi、Yoshimura Kosuke、Kitagawa Hiroki、Kaiki Yuki、Morikawa Norifumi、Takahashi Shinya
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 29 Issue: 2 Pages: 186-192
- DOI
  10.1016/j.jiac.2022.10.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06723, KAKENHI-PROJECT-22K06767
[Journal Article] Ceftolozane-Tazobactam Pharmacokinetics in the Abdominal Tissue of Patients Undergoing Lower Gastrointestinal Surgery: Dosing Considerations Based on Site-Specific Pharmacodynamic Target Attainment2022
- Author(s)
  Yoshimura Kosuke、Ohge Hiroki、Ikawa Kazuro、Uegami Shinnosuke、Watadani Yusuke、Shigemoto Norifumi、Hirano Toshinori、Kitagawa Hiroki、Kaiki Yuki、Morikawa Norifumi、Takahashi Shinya
- Journal Title
  
  Infectious Diseases and Therapy
  
  Volume: 12 Issue: 1 Pages: 193-207
- DOI
  10.1007/s40121-022-00720-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06767, KAKENHI-PROJECT-22K06723
[Journal Article] Pharmacokinetics of piperacillin-tazobactam in plasma, peritoneal fluid and peritoneum of surgery patients, and dosing considerations based on site-specific pharmacodynamic target attainment.2017
- Author(s)
  Murao Naoki, Ohge Hiroki, Ikawa Kazuro, Watadani Yusuke, Uegami Shinnosuke, Shigemoto Norifumi, Shimada Norimitsu, Yano Raita, Kajihara Toshiki, Uemura Kenichiro, Murakami Yoshiaki, Morikawa Norifumi, Sueda Taijiro.
- Journal Title
  
  Int J Antimicrob Agents.
  
  Volume: 50 Issue: 3 Pages: 393-398
- DOI
  10.1016/j.ijantimicag.2017.03.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08590
[Journal Article] Bacillus cereusに対する二酸化塩素の抗芽胞作用に関する検討2014
- Author(s)
  若狭麻未、福辻賢治、齊藤峰輝、大毛宏樹、山田作夫
- Journal Title
  
  日本臨床腸内微生物学会誌
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-24591494
[Journal Article] Bacillus cereus芽胞に対する二酸化塩素の抗菌効果2014
- Author(s)
  若狭麻美, 福辻賢治, 齊藤峰輝, 大毛宏樹, 山田作夫
- Journal Title
  
  日本臨床腸内微生物学会誌
  
  Volume: 16 Pages: 54-63
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591494
[Presentation] Piperacillin配合剤、ceftolozane 配合剤の腹膜組織中PK/PD解析～腹膜炎治療法の評価～2023
- Author(s)
  有吉映、猪川和朗、林宏和、勝田弘輝、吉村幸祐、大毛宏喜、森川則文
- Organizer
  日本医療薬学会第6回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-22K06723
[Presentation] Oral And rectal colonization by antimicrobial-resistant Gram-Negative bacteria in older adults requiring severe intensive nursing care admitted to a long-term care facility2023
- Author(s)
  Yoshikawa M, Haruta A, Kajihara T, Takeuchi M, Kawada-Matsuo M, Nguyen-Tra Le M, Tsuga K, Komatsuzawa H, Ohge H, Sugai M
- Organizer
  IAGG Asia/Oceania Regional Congress2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10248
[Presentation] Oral and rectal colonization by Antimicrobial-resistant gram negative bacteria in older adults requiring severe intensive nursing care admitted to a long-term care facility2023
- Author(s)
  Yoshikawa M, Haruta A, Kajihara T, Takeuchi M, Kawada-Matsuo M, Le MN, Tsuga K, Komatsuzawa H, Ohge H, Sugai M
- Organizer
  IAGG Asia/Oceania regional congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10248
[Presentation] Clinical pharmacokinetics of intravenous metronidazole in plasma, peritoneal fluid, peritoneum and adipose tissue.2020
- Author(s)
  Taogoshi H, Ohge H, Ikawa K, Watadani Y, Uegami S, Shigemoto N, Shimada N, Omori K, Kitano H, Kuroo Y, Kitagawa H, Yoshimura K, Uemura K, Murakami Y, Morikawa N, Takahashi S.
- Organizer
  Digestive Disease Week 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07221
[Presentation] 結腸直腸手術患者におけるメトロニダゾール静注の血漿・腹水・腹部組織中濃度推移2019
- Author(s)
  垰越宏幸、大毛宏喜、猪川和朗、渡谷祐介、上神慎之介、繁本憲文、嶋田徳光、大森慶太郎、北野弘之、黒尾優太、北川浩樹、吉村幸祐、森川則文
- Organizer
  第32回日本外科感染症学会総会学術集会
- Data Source
  KAKENHI-PROJECT-19K07221
[Presentation] β-ラクタム系抗菌薬の腹水移行性と腹膜炎治療法の部位特異的PK/PD評価～ピペラシリン配合剤、セフォゾプラン、イミペネム～2019
- Author(s)
  山田和奈、猪川和朗、小田川周平、松山侑未、宇多真智子、大毛宏喜、森川則文
- Organizer
  第29回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K07221
[Presentation] Intraperitoneal penetration of piperacillin-tazobactam in patients undergoing abdominal surgery.2016
- Author(s)
  Ohge H, Murao N, Ikawa K, Watadani Y, Uegami S, Shigemoto N, Shimada N, Kajihara T, Yano R, Morikawa N, Sueda T.
- Organizer
  56th Interscience Conference on Antimicrobial Agents and Chemotherapy & 116th General Meeting of the American Society for Microbiology
- Place of Presentation
  Boston, USA
- Year and Date
  2016-06-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08590
[Presentation] メロペネムの膵液への移行に関する薬物動態とグラム陰性桿菌に対する至適投与法の検討.2015
- Author(s)
  近藤成, 猪川和朗, 村上義昭, 上村健一郎, 橋本泰司, 中川直哉, 佐々木勇人, 大毛宏喜, 森川則文, 末田泰二郎.
- Organizer
  第46回日本膵臓学会大会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-19
- Data Source
  KAKENHI-PROJECT-15K08590
[Presentation] 薬剤耐性緑膿菌に対するコリスチン単剤・併用投与法のPK-PD検討.2015
- Author(s)
  横山雄太, 猪川和朗, 長岡里枝, 小野寺一, 木場由美子, 原稔典, 横崎典哉, 大毛宏喜, 森川則文.
- Organizer
  第63回日本化学療法学会西日本支部総会・第85回日本感染症学会西日本地方会学術集会・第58回日本感染症学会中日本地方会学術集会
- Place of Presentation
  奈良
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-15K08590
[Presentation] Bacillus cereusに対する二酸化塩素の抗芽胞作用に関する検討
- Author(s)
  若狭麻未、福辻賢治、齊藤峰輝、大毛宏樹、山田作夫
- Organizer
  第16回日本臨床腸内微生物学会総会・学術集会
- Place of Presentation
  広島大学応仁会館（広島市）
- Data Source
  KAKENHI-PROJECT-24591494
[Presentation] 二酸化塩素の抗芽胞作用に関する超微形態的検討
- Author(s)
  山田作夫、福辻賢治、大毛宏喜
- Organizer
  第60回日本化学療法学会
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Data Source
  KAKENHI-PROJECT-24591494
[Presentation] 二酸化塩素および次亜塩素酸ナトリウムの抗菌作用に関する顕微科学的検討
- Author(s)
  山田作夫、福辻賢治、氏峰栞里、刀袮重信、大毛宏喜
- Organizer
  第95回日本細菌学会関東支部総会他2学会合同会議
- Place of Presentation
  ホテル日航東京（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-24591494

1. Ikawa Kazuro (40363048)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. 森川則文 (30346481)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. Yamada Sakuo (00122458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. Yoshikawa Mineka (00444688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 菅井基行 (10201568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 太田耕司 (20335681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 梶原俊毅 (40816948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 吉田光由 (50284211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鹿山鎭男 (50432761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 津賀一弘 (60217289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 小松澤均 (90253088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 林哲太郎 (60612835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 野村俊仁 (00882060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小畠浩平 (10749998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 池田健一郎 (50624863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 坂口剛正 (70196070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ohge Hiroki 大毛 宏喜

大毛 宏喜 オオゲ ヒロキ

Research Projects

Research Products

Co-Researchers

抗嫌気性菌薬療法の感染組織中動態・患者病態因子・薬剤耐性機構に基づく個別最適化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒトゲノム内在性ウイルス配列によるX精子運動能制御の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding the distribution of resistant bacteria in the oral cavity and the impact of oral hygiene management by dentists on healthcare-associated pneumonia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optimization of antimicrobial therapy based on integrated quantitative evaluation of physiological pharmacokinetics, disease pharmacodynamics and drug-resistance mechanisms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optimization of antimicrobial therapy based on relation and interaction among drug, causative organism and host immunity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the bactericidal effect of chlorine dioxide against bacterial spores.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pharmacokinetics of cefmetazole in plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients scheduled for lower gastrointestinal surgery: Dosing considerations based on site-specific pharmacodynamic target attainment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacokinetics of flomoxef in plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients undergoing lower gastrointestinal surgery: Dosing considerations based on site-specific pharmacodynamic target attainment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ceftolozane-Tazobactam Pharmacokinetics in the Abdominal Tissue of Patients Undergoing Lower Gastrointestinal Surgery: Dosing Considerations Based on Site-Specific Pharmacodynamic Target Attainment2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacokinetics of piperacillin-tazobactam in plasma, peritoneal fluid and peritoneum of surgery patients, and dosing considerations based on site-specific pharmacodynamic target attainment.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bacillus cereusに対する二酸化塩素の抗芽胞作用に関する検討2014

Author(s)

Journal Title

Data Source

[Journal Article] Bacillus cereus芽胞に対する二酸化塩素の抗菌効果2014

Author(s)

Journal Title

Data Source

[Presentation] Piperacillin配合剤、ceftolozane 配合剤の腹膜組織中PK/PD解析～腹膜炎治療法の評価～2023

Author(s)

Organizer

Data Source

[Presentation] Oral And rectal colonization by antimicrobial-resistant Gram-Negative bacteria in older adults requiring severe intensive nursing care admitted to a long-term care facility2023

Author(s)

Organizer

Data Source

[Presentation] Oral and rectal colonization by Antimicrobial-resistant gram negative bacteria in older adults requiring severe intensive nursing care admitted to a long-term care facility2023

Author(s)

Organizer

Ohge Hiroki 大毛宏喜

大毛宏喜オオゲヒロキ