Ono Shigehiro 小野重弘

… Alternative Names

ONO Shigehiro 小野重弘

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Researcher Number	70379882
External Links
Affiliation (Current)	2025: 広島大学, 病院(歯), 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 広島大学, 医系科学研究科(歯), 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 助教 2012 – 2016: 広島大学, 医歯薬保健学研究院(歯), 助教 2013 – 2014: 広島大学, 医歯薬保健学研究院, 助教 2012: 広島大学, 大学院・医歯薬保健学研究院, 助教 … More 2011: 広島大学, 医歯(薬)学総合研究科, 助教 2011: 広島大学, 大学院・医歯薬学総合研究科, 助教研 2007 – 2011: Hiroshima University, 大学院・医歯薬学総合研究科, 助教 2010: 広島大学, 医歯薬学総合研究科, 助教 2005 – 2006: 広島大学, 大学院医歯薬学総合研究科, 助手 2005: 広島大学, 大学院・医歯薬学総合研究科, 助手 2005: Hiroshima University, Graduate School of Biomedical Sciences, Assistant, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 口腔扁平上皮癌 / 口腔癌 / 遺伝子 / 癌幹細胞 / 上皮間葉移行 / 転移 / 抗癌剤 / EMT / 歯学 / 癌 … More / 幹細胞 / 唾液腺癌 / 浸潤 / 高度浸能 / 扁平上皮癌 / 転写因子 / 癌の浸潤・転移 / 浸潤・転移 / 上皮・間葉移行 / 臨床腫瘍学 … More Except Principal Investigator 口腔癌 / 癌幹細胞 / 上皮・間葉移行 / p63 / 浸潤・転移 / 口腔扁平上皮癌 / 唾液腺癌 / 癌の浸潤・転移 / 扁平上皮癌 / 転写因子 / 上皮間葉移行 / CD44 / 抗癌剤抵抗性 / ハイドロキシアパタイト / EMT / 遺伝子発現 / Snail / Beclin-1 / 核内受容体 / AMT / amoeboid-like CD44high細胞 / シリコンゲル / メカニカルストレス / アポトーシス抵抗性 / 骨補填材 / 骨形成能 / アパタイト / 抗菌ペプチド / 抗菌 / ラミニン332 / 細胞外基質 / ハイドロゲル / 唾液腺癌幹細胞 / NR4A2 / アポトーシス / Tumor Invasion and Metastasis / Oral Cancer / Micro-array / Matrix Proteinase / Adhesion Molecule / Gene Expression / Transcription Factor / Invasion and Metastasis / Squomous Cell Carcinoma / Epithelial Mesenchymal Transition / telomerase reverse transcriptase / Wnt-5a / Wnt-4 / MMP-2 / E-cadherin / 三次元培養 / DNAチップ / 浸潤、転移 / マイクロアレイ / 基質分解酵素 / 接着因子 / 顎骨再建 / 骨芽細胞 / ＦＧＦ / メラトニン / ｈｙｄｒｏｘｙａｐａｔｉｔｅ / ｂｏｎｅ / ＡＬＤＨ１ / GSK3β / ALDH1 / RHAMM / 侵潤・転移 / がん微小環境 / 口腔がん / 上皮整合性 / p^63 / 発現遺伝子 / 浸潤転移 Less

CD44高発現口腔扁平上皮癌細胞におけるBeclin-1を介した癌幹細胞形質の制御機構の解明
- Principal Investigator
  
  重石英生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Elucidation of mechanotransduction mechanisms in oral squamous cell carcinoma cells with high CD44 expression
- Principal Investigator
  
  Shigeishi Hideo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Involvement of EMT and cancer stem cells in the mechanism of Snail-induced acquisition of metastatic potential of oral cancerPrincipal Investigator
- Principal Investigator
  
  Ono Shigehiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Study on the Mechanism of Nuclear Receptor-mediated Acquisition of Anticancer Drug Resistance in Human Salivary Gland Tumors
- Principal Investigator
  
  ISHIOKA YASUKI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
The development of high functional interconnected porous hydroxyapatite with bone formation ability and antibacterial activity
- Principal Investigator
  
  Takechi Masaaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Analysis of mechanical stress-mediated control mechanism of cancer stem cell character in oral squamous cell carcinoma.
- Principal Investigator
  
  Shigeishi Hideo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Analysis of the invasive mechanism of salivary gland cancer induced by novel EMT-related gene DUOX1Principal Investigator
- Principal Investigator
  
  Ono Shigehiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Analysis of NR4A2-associated mechanism of anti-cancer drug resistance in salivary gland cancer stem cells.
- Principal Investigator
  
  Ishioka Yasuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Functional analysis of GSK3beta in human oral cancer stem cells
- Principal Investigator
  
  Shigeishi Hideo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Establishment of jaw bone reconstruction treatment using osteoblast/interconnected porous hydroxyapatite ceramics composite
- Principal Investigator
  
  masaaki takechi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
The analysis of the invasion mechanism of oral squamous cell carcinoma induced by new EMT-related gene MTDHPrincipal Investigator
- Principal Investigator
  
  Ono Shigehiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Expression and functional analysis of RHAMM in human salivary gland carcinomas
- Principal Investigator
  
  SHIGEISHI HIDEO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
EMTによる口腔癌高度悪性化機構の解明と制御
- Principal Investigator
  
  鎌田伸之
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Analysis of epithelial integrity system in tumor invasion and metastasis of oral cancer
- Principal Investigator
  
  HIGASHIKAWA Koichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
The participation of micro RNA acquiring the ability with high-invasiveness via Epithelial-mesenchymal Transition in squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  ONO Shigehiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Functional Analysis of EMT and p63 in the invasiveness and metastasis of Oral cancer
- Principal Investigator
  
  HIGASHIKAWA Koichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
VEGF-C is required for the infiltration of squamous cell carcinomavia epithelial-mesenchymal transitionPrincipal Investigator
- Principal Investigator
  
  ONO Shigehiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Control of invasion and metastasis of oral cancer via clarification of the epithelial-mesenchymal transition
- Principal Investigator
  
  KAMATA Nobuyuki
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
口腔癌におけるEGFRの遺伝子変異・増幅・発現とそれを標的とした治療薬の基礎研究Principal Investigator
- Principal Investigator
  
  小野重弘
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Snail-induced downregulation of deltaNp63 acquires invasive phenotype of human squamous cell carcinoma
- Principal Investigator
  
  HIGASHIKAWA Koichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
Analysis of Molecular Mechanisms of Invasion and Metastasis of Oral Cancer via Epithelial-Mesenchymal Transition
- Principal Investigator
  
  KAMATA Nobuyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
  The University of Tokushima

[Journal Article] Chemical inhibition of LSD1 leads to epithelial to mesenchymal transition in vitro of an oral squamous cell carcinoma OM-1 cell line via release from LSD1-dependent suppression of ZEB1.2023
- Author(s)
  Yamakado N, Okuda S, Tobiume K, Uetsuki R, Ono S, Mizuta K, Nakagawa T, Aikawa T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: in press Pages: 23-29
- DOI
  10.1016/j.bbrc.2023.01.062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10145, KAKENHI-PROJECT-19K10266, KAKENHI-PROJECT-20K10139, KAKENHI-PROJECT-22K10119, KAKENHI-PROJECT-22K10171
[Journal Article] Melatonin enhances cisplatin-induced cell death through inhibition of DERL1 in mesenchymal-like CD44high OSCC cells.2022
- Author(s)
  Shigeishi H, Yokoyama S, Murodumi H, Sakuma M, Fukada S, Okuda S, Yamakado N, Ono S, Takechi M, Ohta K.
- Journal Title
  
  Journal of Oral Pathology & Medicine
  
  Volume: 51 Issue: 3 Pages: 281-289
- DOI
  10.1111/jop.13242
- Data Source
  KAKENHI-PROJECT-20K10138
[Journal Article] Dexamethasone resets stable association of nuclear Snail with LSD1 concomitant with transition from EMT to partial EMT2022
- Author(s)
  Satoshi Okuda, Nao Yamakado, Koichiro Higashikawa, RyoUetsuki, Fumi Ishida, Andra Rizqiawan, Shigehiro Ono, Kuniko Mizuta, Nobuyuki Kamata, Kei Tobiume
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 30 Pages: 101277-101277
- DOI
  10.1016/j.bbrep.2022.101277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19161, KAKENHI-PROJECT-20K10139
[Journal Article] In vitro investigation of the cell compatibility and antibacterial properties of titanium treated with calcium and ozone.2021
- Author(s)
  Takechi, M., Takamoto, M., Ninomiya, Y., Ono, S., Mizuta, K., Nakagawa, T., Shigeishi, H., Ohta, K., Ishikawa, K. and Tsuru K.
- Journal Title
  
  Dental Materials Journal
  
  Volume: - Issue: 3 Pages: 712-718
- DOI
  10.4012/dmj.2020-224
- NAID
  130008045415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09790, KAKENHI-PROJECT-19K10309
[Journal Article] Effects of miR-224-5p-enhanced downregulation of PANX1 on docetaxel-induced apoptosis in amoeboid-like CD44high oral cancer cells.2021
- Author(s)
  Yokoyama S, Shigeishi H, Murodumi H, Sakuma M, Ono S, Tobiume K, Sugiyama M, Ohta K, Takechi M.
- Journal Title
  
  European Journal of Oral Sciences
  
  Volume: 129 Issue: 5
- DOI
  10.1111/eos.12812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10138
[Journal Article] Morphological Evaluation of Bone by CT to Determine Primary Stability-Clinical Study2020
- Author(s)
  Takechi Masaaki, Ishioka Yasuki, Ninomiya Yoshiaki, Ono Shigehiro, Tada Misato, Nakagawa Takayuki, Sasaki Kazuki, Murodumi Hiroshi, Shigeishi Hideo, Ohta Kouji
- Journal Title
  
  Materials (Basel)
  
  Volume: 13 Issue: 11 Pages: 2605-2605
- DOI
  10.3390/ma13112605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10267, KAKENHI-PROJECT-18K09790
[Journal Article] Differential regulation by IFN γ on TNF α induced chemokine expression in synovial fibroblasts from temporomandibular joint.2017
- Author(s)
  Ohta K, Naruse T, Kato H, Ishida Y, Nakagawa T, Ono S, Shigeishi H, Takechi M.
- Journal Title
  
  Mol Med Rep
  
  Volume: 16 Pages: 6850-6857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11837
[Journal Article] CD44high /ALDH1high head and neck squamous cell carcinoma cells exhibit mesenchymal characteristics and GSK3β-dependent cancer stem cell properties.2016
- Author(s)
  Seino S, Shigeishi H, Hashikata M, Higashikawa K, Tobiume K, Uetsuki R, Ishida Y, Sasaki K, Naruse T, Rahman MZ, Ono S, Simasue H, Ohta K, Sugiyama M, Takechi M.
- Journal Title
  
  J Oral Pathol Med.
  
  Volume: 45(3) Pages: 180-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11684
[Journal Article] Snail-induced CD44high cells in HNSCC with high ABC transporter capacity exhibit potent resistance to cisplatin and docetaxel.2016
- Author(s)
  Hashikata M, Shigeishi H, Okui G, Yamamoto K, Tobiume K, Seino S, Uetsuki R, Kato H, Ishioka Y, Ono S, Ohta K, Higashikawa K, Sugiyama M, Takechi M.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 9(8) Pages: 7908-7918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26463005
[Journal Article] Snail-induced CD44high cells in HNSCC with high ABC transporter capacity exhibit potent resistance to cisplatin and docetaxel.2016
- Author(s)
  Hashikata M, Shigeishi H, Okui G, Yamamoto K, Tobiume K, Seino S, Uetsuki R, Kato H, Ishioka Y, Ono S, Ohta K, Higashikawa K, Sugiyama M, Takechi M.
- Journal Title
  
  Int J Clin Exp Pathol.
  
  Volume: 9(8) Pages: 7908-7918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11684
[Journal Article] CD44(high) /ALDH1(high) head and neck squamous cell carcinoma cells exhibit mesenchymal characteristics and GSK3β-dependent cancer stem cell properties.2016
- Author(s)
  Seino S, Shigeishi H, Hashikata M, Higashikawa K, Tobiume K, Uetsuki R, Ishida Y, Sasaki K, Naruse T, Rahman MZ, Ono S, Simasue H, Ohta K, Sugiyama M, Takechi M.
- Journal Title
  
  J Oral Pathol Med
  
  Volume: 45 Issue: 3 Pages: 180-188
- DOI
  10.1111/jop.12348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11290, KAKENHI-PROJECT-26462813, KAKENHI-PROJECT-26463005, KAKENHI-PROJECT-25463085, KAKENHI-PROJECT-24390454, KAKENHI-PROJECT-26463043
[Journal Article] Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients.2016
- Author(s)
  Shigeishi H, Ono S, Higashikawa K, Tada M, Ishida F, Okui G, Okumura T, Fukui A, Kubozono K, Yamamoto K, Ishida Y, Seino S, Hashikata M, Sasaki K, Naruse T, Rahman MZ, Uetsuki R, Nimiya A, Takamoto M, Dainobu K, Tokikazu T, Nishi H, Sugiyama M, Takechi M.
- Journal Title
  
  Exp Ther Med.
  
  Volume: 12 Issue: 3 Pages: 1922-1928
- DOI
  10.3892/etm.2016.3532
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26463043, KAKENHI-PROJECT-15K11250
[Journal Article] Clinicopathological analysis of salivary gland carcinomas and literature review.2015
- Author(s)
  Shigeishi H, Ohta K, Okui G, Seino S, Hashikata M, Yamamoto K, Ishida Y, Sasaki K, Naruse T, Rahman MZ, Uetsuki R, Nimiya A, Ono S, Shimasue H, Higashikawa K, Sugiyama M, Takechi M.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 3(1) Pages: 202-206
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26463005
[Journal Article] Autocrine galectin-1 promotes collective cell migration of squamous cell carcinoma cells through up-regulation of distinct integrins.2013
- Author(s)
  Rizqiawan A, Tobiume K, Okui G, Yamamoto K, Shigeishi H, Ono S, Shimasue H, Takechi M, Higashikawa K, Kamata N.
- Journal Title
  
  .Biochem Biophys Res Commun.
  
  Volume: 441(4) Issue: 4 Pages: 904-910
- DOI
  10.1016/j.bbrc.2013.10.152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592734, KAKENHI-PROJECT-23592963, KAKENHI-PROJECT-24390454, KAKENHI-PROJECT-24592988
[Journal Article] AKT primes Snail-induced EMT concomitantly with the collective migration of squamous cells.2013
- Author(s)
  Okui G, Tobiume K, Rizqiawan A, Yamamoto K, Shigeishi H, Ono S, Higashikawa K, Kamata N
- Journal Title
  
  J Cell Biochem
  
  Volume: (In press) Issue: 9 Pages: 2039-2049
- DOI
  10.1002/jcb.24545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249066, KAKENHI-PROJECT-23592734, KAKENHI-PROJECT-23592963, KAKENHI-PROJECT-24390454, KAKENHI-PROJECT-24659893, KAKENHI-PROJECT-25861941
[Journal Article] Risk of bacterial contamination of bone harvesting devices used for autogenous bone graft in implant surgery.2013
- Author(s)
  Takamoto M, Takechi M, Ohta K, Ninomiya Y, Ono S, Shigeishi H, Tada M, Kamata N
- Journal Title
  
  Head Face Med
  
  Volume: 9 Issue: 1 Pages: 3-3
- DOI
  10.1186/1746-160x-9-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249066, KAKENHI-PROJECT-23592924, KAKENHI-PROJECT-23592993, KAKENHI-PROJECT-24659893
[Journal Article] Autocrine galectin-1 promotes collective cell migration of squamous cell carcinoma cells through up-regulation of distinct integrins.2013
- Author(s)
  Rizqiawan A, Tobiume K, Okui G, Yamamoto K, Shigeishi H, Ono S, Shimasue H, Takechi M, Higashikawa K, Kamata N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 441 Pages: 904-910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592963
[Journal Article] 口腔扁平上皮癌における癌幹細胞の特性(総説)2013
- Author(s)
  重石英生、東川晃一郎、奥井岳、小野重弘、太田耕司、武知正晃、杉山勝、鎌田伸之
- Journal Title
  
  日本口腔組織培養学会誌
  
  Volume: 22(2) Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592963
[Journal Article] Snail promotes Cyr61 secretion to prime collective cell migration and form invasive tumor nests in squamous cell carcinoma.2013
- Author(s)
  Tanaka F, Rizqiawan A, Higashikawa K, Tobiume K, Okui G, Shigeishi H, Ono S, Shimasue H, Kamata N.
- Journal Title
  
  Cancer Lett
  
  Volume: 329(2) Issue: 2 Pages: 243-252
- DOI
  10.1016/j.canlet.2012.11.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592734, KAKENHI-PROJECT-23592963, KAKENHI-PROJECT-24390454, KAKENHI-PROJECT-24592988, KAKENHI-PROJECT-24659893
[Journal Article] Snail promotes Cyr61 secretion to prime collective eellmigration and form invasive tumor nests in squamous cell carcinoma.2013
- Author(s)
  Tanaka F, Rizqiawan A, Higashikawa K, Tobiume K, Okui G, Shigeishi H, Ono S, Shimasue H, Kamata N
- Journal Title
  
  Cancer Lett
  
  Volume: 329(2) Pages: 243-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249066
[Journal Article] 口腔扁平上皮癌における癌幹細胞の特性（総説）2013
- Author(s)
  重石　英生、東川　晃一郎、奥井　岳、小野　重弘、太田　耕司、武知　正晃、杉山　勝、鎌田　伸之
- Journal Title
  
  日本口腔組織培養学会誌
  
  Volume: 22 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592963
[Journal Article] Increased telomerase activity and hTERT expression in human salivary gland carcinomas2011
- Author(s)
  Shigeishi H, Sugiyama M, Tahara H, Ono S, Kumar Bhawal U, Okura M, Kogo M, Shinohara M, Shindoh M, Shintani S, Hamakawa H, Takata T, Kamata N
- Journal Title
  
  Oncol Lett
  
  Volume: 1;2(5) Pages: 845-885
- DOI
  10.3892/ol.2011.354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592963
[Journal Article] PGE2 targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction.2011
- Author(s)
  Shigeishi H, Higashikawa K, Hatano H, Okui G, Tanaka F, Tran TT, Rizqiawan A, Ono S, Tobiume K, Kamata N.
- Journal Title
  
  Cancer Letter
  
  Volume: 28 Pages: 227-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592963
[Journal Article] PGE(2) targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction2011
- Author(s)
  Shigeishi H, Higashikawa K, Hatano H, Okui G, Tanaka F, Tran TT, Rizqiawan A, Ono S, Tobiume K, Kamata N
- Journal Title
  
  CancerLett
  
  Volume: 307(2) Pages: 227-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592526
[Journal Article] Increased telomerase activity and hTERT expression in human salivary gland carcinomas2011
- Author(s)
  Shigeishi H, Sugiyama M, Tahara H, Ono S, Ujjal Kumar Bhawal, Okura M, Kogo M, Shinohara M, Shindoh M, Shintani S, Hamakawa H, Takata T, Kamata N.
- Journal Title
  
  Oncology Letters
  
  Volume: 2 Pages: 2011-2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592963
[Journal Article] PGE_2 targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction2011
- Author(s)
  重石英生
- Journal Title
  
  Cancer Letters
  
  Volume: 307 Issue: 2 Pages: 227-236
- DOI
  10.1016/j.canlet.2011.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J06035, KAKENHI-PROJECT-23592734, KAKENHI-PROJECT-23592963
[Journal Article] Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas.2010
- Author(s)
  Ohta K, Ogawa I, Ono S, Taki M, Mizuta K, Miyauchi M, Takechi M, Shigeishi H, Takata T, Kamata N.
- Journal Title
  
  Oncol Rep.
  
  Volume: 24(1) Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791999
[Journal Article] Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and-unstained areas.2010
- Author(s)
  Ohta K, Ogawa I, Ono S, Taki M, Mizuta K, Miyauchi M, Takechi M, Shigeishi H, Takata T, Kamata N.
- Journal Title
  
  Oncol Rep. 24(1)
  
  Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791999
[Journal Article] DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma.2009
- Author(s)
  Higashikawa K, Yoneda S, Tobiume K, Saitoh M, Taki M, Mitani Y, Shigeishi H, Ono S, Kamata N
- Journal Title
  
  Int J Cancer 124(12)
  
  Pages: 2837-2844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma2009
- Author(s)
  Higashikawa K, Yoneda S, Tobiume K, Saitoh, M, Taki M, Mitani Y, Shigeishi H, Ono S, Kamata N.
- Journal Title
  
  Int J Cancer 124
  
  Pages: 2837-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma2009
- Author(s)
  Higashikawa K, Yoneda S, Tobiume K, Saitoh M, Taki M, Mitani Y, Shigeishi H, Ono S, Kamata N
- Journal Title
  
  Int J Cancer
  
  Volume: 124(12) Pages: 2837-2844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592526
[Journal Article] Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas.2009
- Author(s)
  Shigeishi H, Fujimoto S, Hiraoka M, Ono S, Taki M, Ohta K, Higashikawa K, Kamata N.
- Journal Title
  
  Int J Oncol. 34(6)
  
  Pages: 1565-1571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791999
[Journal Article] DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma.2009
- Author(s)
  Higashikawa K, Yoneda S, Tobiume K, Saitoh M, Taki M, Mitani Y, Shigeishi H, Ono S, Kamata N.
- Journal Title
  
  Int J Cancer. 124(12)
  
  Pages: 2837-2844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791999
[Journal Article] Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas2009
- Author(s)
  Shigeishi H, Fujimoto S, Hiraoka M, OnoS, Taki M, Ohta K, Higashikawa K, Kamata N
- Journal Title
  
  Int J Oncol
  
  Volume: 34(6) Pages: 1565-1571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592526
[Journal Article] Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas.2009
- Author(s)
  Shigeishi H, Fujimoto S, Hiraoka M, Ono S, Taki M, Ohta K, Higashikawa K, Kamata N
- Journal Title
  
  Int J Oncol 34(6)
  
  Pages: 1565-1571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma2009
- Author(s)
  Higashikawa K, Yoneda S, Tobiume K, Saitoh M, Taki M, Mitani Y, Shigeishi H, Ono S, Kamata N
- Journal Title
  
  Int J Cancer 124(12)
  
  Pages: 2837-2844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592337
[Journal Article] Gene expression profiling to identify genes associated with high-invasiveness in human squamous cell carcinoma with epithelial-to-mesenchymal transition.2008
- Author(s)
  Higashikawa K, Yoneda S, Taki M, Shigeishi H, Ono S, Tobiume K, Kamata N
- Journal Title
  
  Cancer Lett 264(2)
  
  Pages: 256-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] Up-regulation of stromal cell-derived factor-1alpha and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma.2008
- Author(s)
  Taki M, Higashikawa K, Yoneda S Ono S, Shigeishi H, Nagayama M, Kamata N
- Journal Title
  
  Oncol Rep 19(4)
  
  Pages: 993-998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] Gene expression profiling to identify genes associated with high-invasiveness in human squamous cell carcinoma with epithelial-to-mesenchymal transition2008
- Author(s)
  Higashikawa K, Yoneda S, Taki M, Shigeishi H, Ono S, Tobiume K, Kamata N
- Journal Title
  
  Cancer Lett 264(2)
  
  Pages: 256-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592337
[Journal Article] Gene expression profiling to identify genes associated with high-invasiveness in human squamous cell carcinoma with epithelial-to-mesenchymal transition2008
- Author(s)
  Higashikawa K, Yoneda S, Taki M, Shigeishi, H, Ono S, Tobiume K, Kamata N.
- Journal Title
  
  Cancer Lett 264(2)
  
  Pages: 256-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] Up-regulation of stromal cell-derived factor-1 alpha and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma2008
- Author(s)
  Taki M, Higashikawa K, Yoneda S, Ono S, Shigeishi H, Nagayama M, Kamata N.
- Journal Title
  
  Oncol Rep 19(4)
  
  Pages: 993-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Journal Article] Increased expression of CENP-H gene in human oral squamous cell carcinomas harboring high-proliferative activity.2006
- Author(s)
  Shigeishi H, Higashikawa K, Ono S, Mizuta K, Ninomiya Y, Yoneda S, Taki M, Kamata N
- Journal Title
  
  OncolRep 16(5)
  
  Pages: 1071-1075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔癌細胞におけるデキサメタゾンによるEMTからpartial EMTへの移行2022
- Author(s)
  山門奈央, 飛梅　圭, 奥田哲史, 植月　亮, 中川貴之, 水田邦子, 小野重弘, 相川友直
- Organizer
  第67回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10139
[Presentation] 当科におけるインプラント撤去に関する臨床的検討2020
- Author(s)
  二宮嘉昭，小野重弘，水田邦子，多田美里，武知正晃
- Organizer
  第65回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-18K09790
[Presentation] 口腔癌におけるEMTが付与する治療抵抗性の解析2019
- Author(s)
  東川晃一郎，植月亮，石田扶美，重石英生，島末洋，小野重弘，武知正晃
- Organizer
  第64回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11874
[Presentation] 口腔癌細胞における癌幹細胞特性とSnail誘導性EMTの関連性解析2019
- Author(s)
  植月亮，東川晃一郎，重石英生，石田扶美，小野重弘，島末洋，武知正晃
- Organizer
  第64回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11874
[Presentation] 舌癌由来細胞株OM-1における分化転換能の解析2018
- Author(s)
  植月亮，東川晃一郎，重石英生，石田扶美，小野重弘，島末洋，武知正晃
- Organizer
  第63回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11874
[Presentation] 口腔扁平上皮癌細胞における上皮幹細胞特性の解析2018
- Author(s)
  植月　亮，小野重弘，武知正晃
- Organizer
  第36回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11874
[Presentation] Semi-stable EMT型口腔癌細胞における上皮幹細胞特性の解析2017
- Author(s)
  植月　亮，東川晃一郎，小野重弘，武知正晃
- Organizer
  第62回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11874
[Presentation] 口腔扁平上皮癌細胞における幹性とEMTとの関連性についてのin vitro解析2016
- Author(s)
  植月亮，東川晃一郎，重石英生，石田扶美，小野重弘，島末洋，武知正晃
- Organizer
  第61回日本口腔外科学会総会・学術大会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-26463043
[Presentation] インプラント治療を目的としたチタンメッシュによる前歯部でのGBRの臨床的検討2016
- Author(s)
  佐々木和起，二宮嘉昭，室積博，石田扶美，水田邦子，小野重弘，太田耕司，武知正晃
- Organizer
  第46回公益社団法人日本口腔インプラント学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-26463009
[Presentation] 連通多孔体ハイドロキシアパタイトを用いた骨造成に関する臨床的検討2015
- Author(s)
  多田美里、二宮嘉昭、太田耕司、中川貴之、小野重弘、武知正晃
- Organizer
  第１９回日本顎顔面インプラント学会
- Place of Presentation
  横須賀
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26463009
[Presentation] CD44high/ALDH1high口腔扁平上皮癌細胞における癌幹細胞形質の解析2015
- Author(s)
  清野紗矢香, 重石英生, 奥井岳, 箸方美帆, 植月亮, 山本一博, 小野重弘, 東川晃一郎, 太田耕司, 島末洋, 武知正晃．
- Organizer
  日本組織培養学会第88回大会
- Place of Presentation
  広島
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-26463005
[Presentation] 連通多孔体ハイドロキシアパタイトを使用した上顎洞底挙上術における組織学的検討2015
- Author(s)
  二宮嘉昭、小野重弘、多田美里、中川貴之、武知正晃
- Organizer
  第１９回日本顎顔面インプラント学会
- Place of Presentation
  横須賀
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26463009
[Presentation] 口腔扁平上皮癌におけるALDH１発現と臨床病理学的指標との関わり2014
- Author(s)
  清野紗矢香，重石英生，奥井　岳，箸方美帆，植月　亮，山本一博，小野重弘，東川晃一郎，武知正晃
- Organizer
  第62回日本口腔科学会　中国・四国地方部会
- Place of Presentation
  徳島市,徳島大学歯学部
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-26463005
[Presentation] 口腔扁平上皮癌細胞における幹細胞形質とGSK3βの関わり2013
- Author(s)
  重石英生、奥井岳、小野重弘、Andra Rizqiawan、東川晃一郎、杉山勝,鎌田伸之
- Organizer
  第67回NPO法人日本口腔科学会学術集会
- Place of Presentation
  栃木
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23592963
[Presentation] Role of galectin 1 in cell migration and invasiveness in human squamous cell carcinoma correlated with EMT2013
- Author(s)
  ANDRA RIZQIAWAN,飛梅圭、奥井岳、山本一博、東川晃一郎、重石英生、小野重弘、鎌田伸之
- Organizer
  第67回NPO法人日本口腔科学会学術集会
- Place of Presentation
  栃木
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23592963
[Presentation] Galectin 1 involved in cell migration and invasion by upregulated Integrin α2 in squamous cell carcinoma correlated with EMT2012
- Author(s)
  Andra R, Okui G, Higashikawa K, Yamamoto K, Shigeishi H, Ono S, Kamata N
- Organizer
  第57回(公社)日本口腔外科学会総会・学術大会
- Place of Presentation
  横浜
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] 口腔扁平上皮癌幹細胞におけるCD44関連シグナル伝達経路の役割2012
- Author(s)
  重石英生, 奥井岳, 小野重弘, 東川晃一郎, 杉山勝, 鎌田伸之
- Organizer
  第49回日本口腔組織培養学会学術大会
- Place of Presentation
  広島
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] 口腔扁平上皮癌におけるEMT誘導に関与するSnailとPI3K-AKT経路2012
- Author(s)
  奥井岳, 東川晃一郎, Andra Rizqiawan, 山本一博, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第57回(公社)日本口腔外科学会総会・学術大会
- Place of Presentation
  横浜
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] Threonin 612 defines the putative pore-forming domain character of GDD1/Ano5/ TMEM16E2012
- Author(s)
  Trail TT, Hirono C, Fujimoto S, Mizuta K, Kubozono K, Sugita M, Kamata N
- Organizer
  第45回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] CD44-related molecular events underline the choice between self-renewal and differentiation of cancer stem cells in OSCC2012
- Author(s)
  Shigeishi H, Higashikawa K, Ono S, Sugiyama M, Kamata N
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] Role of galectin-1 in cell migration and invasiveness in human squamous cell carcinoma correlated with Epithelial Mesencymal Transition.2012
- Author(s)
  Andra R, Okui G, Higashikawa K, Yamamoto K, Shigeishi H, Ono S, Kamata. N
- Organizer
  10^<th> Asian Congress on Oral and Maxillofacial Surgery
- Place of Presentation
  Bali Indonesia
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] PI3K-Akt dependent cell motility primes snail-induced EMT in squamous cells2012
- Author(s)
  Okui G, Higashikawa K, Tobiume K, Rizqiawan A, Ono S, Shigeishi H, Kamata N
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22249066
[Presentation] CD44-related molecular events underline the choice between self-renewal and differentiation of cancer stem cells in SCC2012
- Author(s)
  Hideo Shigeishi, Koichiro Higashikawa, Shigehiro Ono, Masaru Sugiyama, Nobuyuki Kamata
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23592963
[Presentation] 口腔扁平上皮癌幹細胞におけるCD44関連シグナル伝達経路の役割2012
- Author(s)
  重石英生、奥井岳、小野重弘、東川晃一郎、杉山勝、鎌田伸之
- Organizer
  第49回日本口腔組織培養学会学術大会
- Place of Presentation
  広島
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23592963
[Presentation] A snail target gene product Cyr61 regulates the invasiveness of squamous cell carcinoma.2010
- Author(s)
  Tanaka F, Higashikawa K, Tobiume K, Ono S, Shigeishi H, Okui G, Kamata N
- Organizer
  第69回日本癌学会・学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21791999
[Presentation] Snailが制御する口腔扁平上皮癌細胞における浸潤能を付与する分泌タンパク2010
- Author(s)
  田中扶美, 東川晃一郎, 奥井岳, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第43回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21791999
[Presentation] ヒト口腔扁平上皮癌におけるNR4A2の発現および機能解析2010
- Author(s)
  重石英生, 東川晃一郎, 波多野寛子, 田中扶美, 小野重弘, 鎌田伸之
- Organizer
  第64回日本口腔科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21791999
[Presentation] 口腔扁平上皮癌細胞における高度浸潤能獲得への Snail 標的分泌型タンパクの関与2009
- Author(s)
  田中扶美, 東川晃一郎, 飛梅圭, 小野重弘, 重石英生, 鎌田伸之
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] EMT型口腔扁平上皮癌細胞におけるgamma-secretase inhibitor抵抗性の解析2009
- Author(s)
  東川晃一郎, 田中扶美, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第54回(社)日本口腔外科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21791999
[Presentation] 口腔扁平上皮癌細胞における高度浸潤能獲得機構の解析2009
- Author(s)
  田中扶美, 東川晃一郎, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第54回(社)日本口腔外科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] A Snail-induced secretory protein associated with the invasiveness of squamous cell carcinoma2009
- Author(s)
  Tanaka F, Higashikawa K, Tobiume K, Ono S, Shigeishi H, Kamata N
- Organizer
  第68回日本癌学会・学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21791999
[Presentation] EMT型口腔扁平上皮癌細胞におけるgamma-secretase inhibitor抵抗性の解析2009
- Author(s)
  東川晃一郎, 田中扶美, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第54回(社)日本口腔外科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌細胞における高度浸潤能獲得へのSnail標的分泌型タンパクの関与2009
- Author(s)
  田中扶美, 東川晃一郎, 飛梅圭, 小野重弘, 重石英生, 鎌田伸之
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] EMT型口腔扁平上皮癌細胞における gamma-secretase inhibitor 抵抗性の解析2009
- Author(s)
  東川晃一郎, 田中扶美, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第54回(社)日本口腔外科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌細胞における高度浸潤能獲得機構の解析2009
- Author(s)
  田中扶美, 東川晃一郎, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第54回(社)日本口腔外科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21791999
[Presentation] 扁平上皮癌細胞における上皮・間葉移行を介したWnt-5aによる高度浸潤能獲得機構2008
- Author(s)
  瀧雅行, 東川晃一郎, 米田進吾, 三谷佳嗣, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] Role and regulation of the EMT target gene VEGF-C expression in Squamous Cell Carcinoma2008
- Author(s)
  小野重弘
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19791520
[Presentation] EMT 型口腔扁平上皮癌細胞の浸潤抑制因子Id3 の解析2008
- Author(s)
  東川晃一郎, 米田進吾, 飛梅圭, 瀧雅行, 三谷佳嗣, 小野重弘, 重石英生, 鎌田伸之
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるRHAMM遺伝子の発現解析2008
- Author(s)
  重石英生, 藤本伸一, 瀧雅行, 小野重弘, 三谷佳嗣, 東川晃一郎, 鎌田伸之
- Organizer
  第53回(社)日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT関連遺伝子VEGF-Cの役割と発現機構2008
- Author(s)
  小野重弘, 三谷佳嗣, 東川晃一郎, 重石英生, 米田進吾, 瀧雅行, 鎌田伸之
- Organizer
  第53回(社)日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 扁平上皮癌細胞におけるWnt-5aによる高度浸潤能獲得機構の解析2008
- Author(s)
  瀧雅行, 東川晃一郎, 米田進吾, 三谷佳嗣, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第53回(社)日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT関連遺伝子VEGF-Cの役割と発現機構2008
- Author(s)
  小野重弘, 三谷佳嗣, 東川晃一郎, 重石英生, 米田進吾, 瀧雅行, 北台靖彦, 鎌田伸之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT 関連遺伝子VEGF-Cの役割と発現機構2008
- Author(s)
  小野重弘, 三谷佳嗣, 東川晃一郎, 重石英生, 米田進吾, 瀧雅行, 北台靖彦, 鎌田伸之
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] Hideo Shigeishi, Shingo Yoneda, Masayuki Taki, Yasuhiko Kitadai, Nobuyuki Kamata Role and regulation of the EMT targetgene VEGF-C expression in Squamous Cell Carcinoma2008
- Author(s)
  Shigehiro Ono, Yoshitsugu Mitani, Koichiro Higashikawa
- Organizer
  67th Annual meeting of the Japanese Cancer Association
- Place of Presentation
  NAGOYA
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19791520
[Presentation] EMT型口腔扁平上皮癌の浸潤をId3 は抑制する2008
- Author(s)
  東川晃一郎, 米田進吾, 飛梅圭, 瀧雅行, 三谷佳嗣, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-19592337
[Presentation] h-pruneの高発現は扁平上皮癌のアノイキスや細胞運動に関与する2008
- Author(s)
  三谷佳嗣, 瀧雅行, 小野重弘, 東川晃一郎, 菊池章, 鎌田伸之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] EMT型口腔扁平上皮癌細胞の浸潤抑制因Id3の解析2008
- Author(s)
  東川晃一郎, 米田進吾, 飛梅圭, 瀧雅行, 三谷佳嗣, 小野重弘, 重石英生, 鎌田伸之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT関連遺伝子VEGF-Cの役割と発現機構2008
- Author(s)
  小野重弘,三谷佳嗣,東川晃一郎,重石英生,米田進吾,瀧雅行,鎌田伸之
- Organizer
  第53回(社)日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-19791520
[Presentation] EMT型口腔扁平上皮癌細胞の浸潤を抑制するId3の解析2008
- Author(s)
  東川晃一郎, 米田進吾, 瀧雅行, 田中扶美, 三谷佳嗣, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第53回(社)日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT関連遺伝子VEGF-Cの役割と発現機構2008
- Author(s)
  小野重弘
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] EMT型口腔扁平上皮癌細胞の浸潤を抑制するId3の解析2008
- Author(s)
  東川晃一郎, 米田進吾, 瀧雅行, 田中扶美, 三谷佳嗣, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第53回日本口腔外科学会総会
- Place of Presentation
  徳島市
- Data Source
  KAKENHI-PROJECT-19592337
[Presentation] 扁平上皮癌細胞における上皮・間葉移行を介したWnt-5aによる高度浸潤能獲得機構2008
- Author(s)
  瀧雅行, 東川晃一郎, 米田進吾, 三谷佳嗣, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 扁平上皮癌細胞におけるEMT標的遺伝子のΔNp63αの発現依存的な浸潤能の変化2007
- Author(s)
  米田進吾, 東川晃一郎, 瀧雅行, 重石英夫, 小野重弘, 三谷佳嗣, 鎌田伸之
- Organizer
  第61回NPO法人日本口腔科学会学術集会
- Place of Presentation
  神戸市
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-19592337
[Presentation] 扁平上皮癌細胞におけるEMT標的遺伝子ΔNp63αの発現依存的な浸潤能の変化2007
- Author(s)
  米田進吾, 東川晃一郎, 瀧雅行, 重石英生, 小野重弘, 三谷佳嗣, 鎌田伸之
- Organizer
  第61回NPO法人日本口腔科学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔癌におけるh-pruneの発現と浸潤・転移との関連2007
- Author(s)
  三谷佳嗣, 米田進吾, 瀧雅行, 小野重弘, 東川晃一郎, 鎌田伸之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT標的遺伝子VEGF-Cの発現と病期進展との関連2007
- Author(s)
  小野重弘, 三谷佳嗣, 重石英生, 米田進吾, 瀧雅行, 東川晃一郎, 北台靖彦, 鎌田伸之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] Expressions of the EMT target gene VEGF-C and disease progression in Oral Squamous Cell Carcinomas2007
- Author(s)
  小野重弘
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] Expressons of the EMT target gene VEGF-C an disease progression in Oral Squamous Cell Carciomas2007
- Author(s)
  小野重弘
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19791520
[Presentation] 上皮・間葉移行を介した扁平上皮癌細胞におけるΔNp63αの発現依存的な浸潤能の変化2007
- Author(s)
  米田進吾, 東川晃一郎, 瀧雅行, 重石英夫, 小野重弘, 三谷佳嗣, 鎌田伸之
- Organizer
  第80回日本組織培養学会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-19592337
[Presentation] Expression of the EMT targetgene VEGF-C and disease progression in oral squamous cell carcinomas2007
- Author(s)
  Shigehiro Ono, Yoshitsugu Mitani, Hideo Shigeishi, Shingo Yoneda, Masayuki Taki, Koichiro Higashikawa, Yasuhiko Kitadai, Nobuyuki Kamata
- Organizer
  66th Annual meeting of the Japanese Cancer Association
- Place of Presentation
  YOKOHAMA
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19791520
[Presentation] 上皮・間葉移行を介した扁平上皮癌の高度浸潤能の獲得における△Np63αの役割2006
- Author(s)
  東川晃一郎, 瀧雅行, 米田進吾, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第51回(社)日本口腔外科学会総会
- Place of Presentation
  北九州
- Year and Date
  2006-10-12
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 上皮・間葉移行を介したp63の発現消失による扁平上皮癌の高度浸潤能の獲得2006
- Author(s)
  東川晃一郎, 米田進吾, 瀧雅行, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT標的遺伝子VEGF-Cの発現と病期進展との関連2006
- Author(s)
  小野重弘, 重石英生, 米田進吾, 瀧雅行, 東川晃一郎, 鎌田伸之
- Organizer
  第51回(社)日本口腔外科学会総会
- Place of Presentation
  北九州
- Year and Date
  2006-10-12
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるCENP-Hの発現解析2006
- Author(s)
  重石英生, 東川晃一郎, 小野重弘, 瀧雅行, 鎌田伸之
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔扁平上皮癌におけるEMT標的遺伝子VEGF-C発現の臨床病理学的意義に関する検討2006
- Author(s)
  小野重弘, 重石英生, 米田進吾, 瀧雅行, 東川晃一郎, 鎌田伸之
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 口腔癌におけるh-pruneの発現と浸潤・転移との関連2006
- Author(s)
  三谷佳嗣, 重石英生, 小野重弘, 米田進吾, 瀧雅行, 東川晃一郎, 鎌田伸之
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] 扁平上皮癌における上皮・間葉移行を介したp63の発現消失2006
- Author(s)
  東川晃一郎, 瀧雅行, 米田進吾, 重石英生, 小野重弘, 鎌田伸之
- Organizer
  第51回(社)日本口腔外科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2006-05-12
- Data Source
  KAKENHI-PROJECT-18390541
[Presentation] CD44-related molecular events underline the choice between self-renewal and differentiation of cancer stem cells in SCC
- Author(s)
  重石　英生、東川　晃一郎、小野　重弘、杉山　勝、鎌田　伸之
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592963
[Presentation] 口腔扁平上皮癌細胞における幹細胞形質とGSK3βの関わり
- Author(s)
  重石　英生、奥井　岳、小野　重弘、Andra Rizqiawan、東川　晃一郎、杉山　勝, 鎌田　伸之
- Organizer
  第67回NPO法人日本口腔科学会学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23592963
[Presentation] 口腔扁平上皮癌幹細胞におけるCD44関連シグナル伝達経路の役割
- Author(s)
  重石　英生、奥井　岳、小野　重弘、東川　晃一郎、杉山　勝、鎌田　伸之
- Organizer
  第49回　日本口腔組織培養学会学術大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23592963

1. SHIGEISHI Hideo (90397943)

# of Collaborated Projects: 12 results

# of Collaborated Products: 75 results
2. HIGASHIKAWA Koichiro (80363084)

# of Collaborated Projects: 9 results

# of Collaborated Products: 70 results
3. KAMATA Nobuyuki (70242211)

# of Collaborated Projects: 7 results

# of Collaborated Products: 68 results
4. TOBIUME Kei (40350037)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
5. 太田耕司 (20335681)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
6. masaaki takechi (00304535)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
7. Ishioka Yasuki (70770840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 中川貴之 (30456230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. TAKI Masayuki (00403551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 29 results
10. MITANI Yoshitsugu (30432678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. NAKANISHI Hiroaki (00243717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MOMOTA Yukihiro (00304543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 北岡栄一郎 (60343307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 横山和博 (00346602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YONEDA Shingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. NINOMIYA Yoshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. TADA Misato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 石田扶美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 杉山勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 相川友直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ono Shigehiro 小野 重弘

ONO Shigehiro 小野 重弘

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Involvement of EMT and cancer stem cells in the mechanism of Snail-induced acquisition of metastatic potential of oral cancerPrincipal Investigator

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Analysis of the invasive mechanism of salivary gland cancer induced by novel EMT-related gene DUOX1Principal Investigator

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The analysis of the invasion mechanism of oral squamous cell carcinoma induced by new EMT-related gene MTDHPrincipal Investigator

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The participation of micro RNA acquiring the ability with high-invasiveness via Epithelial-mesenchymal Transition in squamous cell carcinomaPrincipal Investigator

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Ono Shigehiro 小野重弘

ONO Shigehiro 小野重弘