KOGA Takaomi 古賀孝臣

Researcher Number	70380615
Affiliation (based on the past Project Information) *help	2014: 九州大学, 医学(系)研究科(研究院), 共同研究員 2013: 九州大学, 医学(系)研究科(研究院), 研究員 2010 – 2012: 九州大学, 大学病院, 講師 2005 – 2008: 九州大学, 大学病院, 講師
Review Section/Research Field	Principal Investigator Human pathology Except Principal Investigator Human pathology / Experimental pathology
Keywords	Principal Investigator CHFR / Aurora-A / BAC / AAH / 喫煙 / 肺扁平上皮癌 / 異常メチル化 / ＣＨＦＲ / 分子標的 / 非小細胞肺癌 … More / smoking / Non-small cell lung cancer / AURORA / リンパ管新生 / 血管新生スイッチ / PDGF-A / 肺腺癌 / エピジェネティックドライバー / 扁平上皮癌 / 腺癌 / EML4-ALK / EGFR変異 / メチル化 / 呼吸器・縦隔 … More Except Principal Investigator 血管新生 / 動脈硬化 / SeV / VEGFs / FGF-2 / 血管リモデリング / 病理学 / 癌 / ポドプラニン / シェディング / シグナル伝達 / 脈管新生 / VEGF / 内皮細胞 / 循環器 / 川崎病 / SIV / cancer / atherosclerosis / arteriogenesis / angiogenesis / vascular remodeling / B / PDGF-A / 周波細胞 / 血管内皮(前駆)細胞 / 周皮細胞 / 血管内(前駆)細胞 / リンパ管新生 / トランスリレーショナルリサーチ / PDGFs / Sev / Tie1 / センダイウイルス / 血管平滑筋細胞 / 脂質沈着 / 発現制御 / 上皮間葉移行 / ユビキチンリガーゼ / 癌抑制遺伝子 / 細胞周期 / フォスファターゼ / 脱リン酸化 / 線維芽細胞 / 樹状細胞 / 免疫学 / リンパ管 / heme oxvgenase-1(HO-1) / PKCη / 糖尿病 / 可溶型Tie-2連関 / Ang-1 / 久山町コホート研究 / PKCアイソフォーム / 遺伝子治療 / podoplanin / PKC アイソフォーム / 色素上皮細胞由来因子(PEDF) / 可溶型Tie-2 Less

肺扁平上皮癌の悪性度に与える分子機構の病理学的・分子生物学的研究Principal Investigator
- Principal Investigator
  
  古賀孝臣
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Pathological studies on molecular basis of failure of vascular homeostasis and pathological vascular remodeling.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Detection of the molecular target in intractable non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  KOGA Takaomi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Moleculo-pathological Study on Vascular Remodeling in Japanese
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic and lymphoangiogenic process
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Elucidation of mechanism of the modification of intratumoral microenvironment in antitumor effect of intratumoral activated dendritic cell therapy
- Principal Investigator
  
  OKANO Shinji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
「脱リン酸化」の視点から見る腫瘍細胞機能修飾の分子病理に関する萌芽的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Clinicopathyological and molecular studies for arising and development of lung AdenocarcinomaPrincipal Investigator
- Principal Investigator
  
  KOGA Takaomi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Moleculo-pathological Study on the Homeostatic and Deregulated Mechanisms of Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERCITY

All 2014 2013 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] PICT1 expression is a poor prognostic factor in non-small cell lung cancer2014
- Author(s)
  Okamura K, Takayama K, Kawahara K, Harada T, Nishio M, Otsubo K, Ijichi K, Kohno M, Iwama E, Fujii A, Ota K, Koga T, Okamoto T, Suzuki A, Nakanishi Y
- Journal Title
  
  Oncoscience
  
  Volume: 1 Pages: 375-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460438
[Journal Article] Diffusivity of intraorbital lymphoma vs. IgG4-related DISEASE: 3D turbo field echo with diffusion-sensitised driven-equilibrium preparation technique.2014
- Author(s)
  Hiwatashi A, Yoshiura T, Togao O, Yamashita K, Kikuchi K, Fujita Y, Yoshikawa H, Koga T, Obara M, Honda H.
- Journal Title
  
  Eur Radiol.
  
  Volume: 24 Issue: 3 Pages: 581-586
- DOI
  10.1007/s00330-013-3058-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791432, KAKENHI-PROJECT-25460438
[Journal Article] Combined therapy of lapatinib and capecitabine effective against local recurrence of breast cancer2013
- Author(s)
  ozoe T, Nozoe E, Iguchi T, Ito S, Ohga T, Koga T, Ezaki T
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 40 Pages: 907-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460438
[Journal Article] CHFR aberrant methylation involves a subset of human lung adenocarcinoma associated with poor clinical outcomes2013
- Author(s)
  Koga T
- Journal Title
  
  Hum Pathol
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Aurora-B overexpression is correlated with aneuploidy and poor prognosis in non-small cell lung cancer2013
- Author(s)
  Takeshita M, Koga T, Takayama K, Ijichi K, Yano T, Maehara Y, Nakanishi Y, Sueishi K
- Journal Title
  
  Lung Cancer
  
  Volume: 80 Issue: 1 Pages: 85-90
- DOI
  10.1016/j.lungcan.2012.12.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316, KAKENHI-PROJECT-25460438
[Journal Article] CHFR aberrant methylation involves a subset of human lung adenocarcinoma associated with poor clinical outcome2013
- Author(s)
  Koga T, Takeshita M, Ijichi K, Yano T, Maehara Y, Sueishi K
- Journal Title
  
  Human Pathol Epub ahead of print
  
  Volume: 44 Issue: 7 Pages: 1382-1390
- DOI
  10.1016/j.humpath.2012.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316, KAKENHI-PROJECT-25460438
[Journal Article] Expression of Brachyury Gene Is a Significant Prognostic Factor for Primary Lung Carcinoma.2013
- Author(s)
  Haro A, Yano T, Kohno M, Yoshida T, Koga T, Okamoto T, Takenoyama M, Maehara Y
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 印刷中 Issue: S3 Pages: 509-516
- DOI
  10.1245/s10434-013-2914-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316, KAKENHI-PROJECT-23592080, KAKENHI-PROJECT-24791464, KAKENHI-PROJECT-25460438
[Journal Article] Localized pleural amyloidosis: report of a case2012
- Author(s)
  Yoshiya S, Maruyama R, Koga T, Shikada Y, Yano T, Maehara Y
- Journal Title
  
  Surg Today
  
  Volume: 42 Issue: 6 Pages: 597-600
- DOI
  10.1007/s00595-012-0122-z
- NAID
  10030622277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Carboplatin plus Paclitaxel in the Successful Treatment of Advanced Inflammatory Myofibroblastic Tumor2012
- Author(s)
  Kubo N, Harada T, Anai S, Otsubo K, Yoneshima Y, Ijichi K, Koga T, Takayama K, Nakanishi Y
- Journal Title
  
  Intern. Med.
  
  Volume: 51 Issue: 17 Pages: 2399-2401
- DOI
  10.2169/internalmedicine.51.7599
- NAID
  130002062341
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Effects of Dietary Genistein on Hormone-Dependent Rat Mammary Carcinogenesis Induced by Ethyl Methanesulphonate2012
- Author(s)
  Ono M, Koga T, Ueo H and Nakano S
- Journal Title
  
  Nutrition and Cancer
  
  Volume: 64 Issue: 8 Pages: 1204-1210
- DOI
  10.1080/01635581.2012.718035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Expression of TrkB and BDNF is associated with poor prognosis in non-small cell lung cancer2012
- Author(s)
  Okamura K, Harada T, Wang S, Ijichi K, Furuyama K, Koga T, Okamoto T, Takayama K, Yano T, Nakanishi Y
- Journal Title
  
  Lung Cancer
  
  Volume: 78 Issue: 1 Pages: 100-106
- DOI
  10.1016/j.lungcan.2012.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] CHFR hypermethylation and EGFR mutation are mutually exclusive, and exhibit contrastive clinical backgrounds and outcomes in non-small-cell lung cancer.2011
- Author(s)
  Koga T, et al.
- Journal Title
  
  Int J Cancer. 2011
  
  Volume: 128(5) Pages: 1009-1017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590315
[Journal Article] CHFR hypermethylation and EGFR mutation are mutually exclusive and exhibit contrastive clinical backgrounds and outcomes in non-small cell lung cancer2011
- Author(s)
  Koga T., et al
- Journal Title
  
  Int J Cancer
  
  Volume: 128 Issue: 5 Pages: 1009-17
- DOI
  10.1002/ijc.25447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-22590316, KAKENHI-PROJECT-22659246
[Journal Article] High podoplanin expression in cancer cells predicts lower incidence of nodal metastasis in patients with lung squamous cell carcinoma2011
- Author(s)
  Suzuki H, Onimaru M, Koga T, Takeshita M, Yano T, Maehara Y, Nakamura S, Sueishi K
- Journal Title
  
  Pathol Res Pract
  
  Volume: 207(2) Issue: 2 Pages: 111-5
- DOI
  10.1016/j.prp.2010.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590315, KAKENHI-PROJECT-22590316
[Journal Article] Role and relevance of TrkB mutations and expression in non-small cell lung cancer2011
- Author(s)
  Harada T, Yatabe Y, Takeshita M, Koga T, Yano T, Wang Y, Giaccone G
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Issue: 9 Pages: 2638-2645
- DOI
  10.1158/1078-0432.ccr-10-3034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] CHFR hypermethylation and EGFR mutation are mutually exclusive, and exhibit contrastive clinical backgrounds and outcomes in non-small-cell lung cancer2011
- Author(s)
  Koga T, Takeshita M,, et al.
- Journal Title
  
  Int J Cancer
  
  Volume: 128 Pages: 1009-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] High podoplanin expression in cancer cells predicts lower incidence of nodal metastasis in patients with lung squamous cell carcinoma2011
- Author(s)
  Suzuki H, Onimaru M, Koga T, et al.
- Journal Title
  
  Pathol Res Pract
  
  Volume: 207 Pages: 111-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Alternative efficacy-predicting markers for paclitaxel instead of CHFR in non-small-cell lung cancer2011
- Author(s)
  Takeshita M, Koga T, Takayama K, Yano T, Maehara Y, Nakanishi Y, Sueishi K
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 10 Issue: 9 Pages: 933-941
- DOI
  10.4161/cbt.10.9.13320
- NAID
  120005227356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Alternative eficacy-predicting markers for paclitaxel instead of CHFR in non-small cell lung cancer2010
- Author(s)
  Takeshita M, Koga T, et al.
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 10 Pages: 933-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Verification of the newly proposed T category (seventh edition of the tumor, node, and metastasis classification) from a clinicopathological viewpoint in non-small cell lung cancer-special reference to tumor size2010
- Author(s)
  Yano T, Morodomi Y, Ito K, Yoshida T, Haro A, Shoji F, Koga T, Maehara Y
- Journal Title
  
  J Thorac Oncol
  
  Volume: 5 Issue: 1 Pages: 45-48
- DOI
  10.1097/jto.0b013e3181c0996c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590316
[Journal Article] Soluble Flt-1 gene transfer ameliorates neointima formation after wire injury in flt-1 tyrosine kinase deficient mice2009
- Author(s)
  Koga J
- Journal Title
  
  Arterioscler Thromb Vasc Biol 29(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209012
[Journal Article] Soluble Flt-1 gene transfer ameliorates neointima formation after wire injury in flt-1 tyrosine kinase deficient mice2009
- Author(s)
  Koga J, Matoba T, Egashira K, Kubo M, Miyagawa M, Iwata E, Sueishi K, Shibuya M, Sunagawa K
- Journal Title
  
  Arterioscler Thromb Vasc Biol 29(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209012
[Journal Article] CHFR expression is preferentially impaired in smoking-related squamous cell carcinoma of the lung, and the diminished expression significantly harms outcomes2008
- Author(s)
  Takeshita M, Koga T, Takayama K, Kouso H, Nishimura-Ikeda Y, Yoshino I, Maehara Y, Nakanishi Y, Sueishi K
- Journal Title
  
  Int J Cancer 123(7)
  
  Pages: 1623-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590352
[Journal Article] CHFR expression is preferentially impaired in smoking-related squamous cell carcinoma of the lung, and the diminished expression significantly harms outcomes2008
- Author(s)
  Takeshita M, Koga T, Takayama K, Kouso H, Nishimura-Ikeda Y, Yoshino I, Maehara Y, Nakanishi Y, Sueishi K
- Journal Title
  
  Int J Cancer 123
  
  Pages: 1623-1630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209012
[Journal Article] An autopsy case report of annuloaortic ectasia with cardiac tamponade ruptured from an aneurysm of the right Valsalva sinus2007
- Author(s)
  Fujii T, Sumiyoshi S, Koga T, Nishizaka M, Matsukawa R, Kuwano H, Sueishi K
- Journal Title
  
  Pathol Res Pract 203
  
  Pages: 671-675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209012
[Journal Article] The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells.2006
- Author(s)
  Duan X, Hisaeda H, Shen J, Tu L, Imai T, Chou B, Murata S, Chiba T, Tanaka K, Fehling HJ, Koga T, Sueishi K, Himeno K
- Journal Title
  
  Int Immunol 18(5)
  
  Pages: 679-687
- NAID
  10020619445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209012
[Presentation] GFR 変異型肺腺癌と、CHFR メチル化陽性肺腺癌の病理学的比較検討2010
- Author(s)
  古賀孝臣
- Organizer
  日本病理学会
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-22590316
[Presentation] EGFR変異型肺腺癌と、CHFRメチル化陽性肺腺癌の病理学的比較検討2010
- Author(s)
  古賀孝臣
- Organizer
  日本病理学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-22590316
[Presentation] 扁平上皮細胞癌における Podoplaninの発現とリンパ節転移との病理学的検討2010
- Author(s)
  鈴木華子、鬼丸満穂、古賀孝臣、竹下正文、矢野篤次郎、前原喜彦、中村誠司、居石克夫
- Organizer
  第51回日本脈管学会総会
- Place of Presentation
  旭川市
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-22590315
[Presentation] 非小細胞肺癌における細胞周期制御分子Aurora-A 及びCHFR 発現の臨床病理学的検討2008
- Author(s)
  竹下正文、古賀孝臣、高祖英典、吉野一郎、前原喜彦、中西洋一、居石克夫
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-19590352

1. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
2. NAKAGAWA Kazunori (50217668)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. OKANO Shinji (10380429)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. ONIMARU Mitsuho (00380626)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
5. IIDA Mitsuo (00127961)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YONEMITSU Yoshikazu (40315065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KIYOHARA Yutaka (80161602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUBO Mitsuaki (30442958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. YAMASHITA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOGA Takaomi 古賀 孝臣

Research Projects

Research Products

Co-Researchers

肺扁平上皮癌の悪性度に与える分子機構の病理学的・分子生物学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathological studies on molecular basis of failure of vascular homeostasis and pathological vascular remodeling.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of the molecular target in intractable non-small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Moleculo-pathological Study on Vascular Remodeling in Japanese

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic and lymphoangiogenic process

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of mechanism of the modification of intratumoral microenvironment in antitumor effect of intratumoral activated dendritic cell therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

「脱リン酸化」の視点から見る腫瘍細胞機能修飾の分子病理に関する萌芽的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinicopathyological and molecular studies for arising and development of lung AdenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Moleculo-pathological Study on the Homeostatic and Deregulated Mechanisms of Vascular Remodeling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] PICT1 expression is a poor prognostic factor in non-small cell lung cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] Diffusivity of intraorbital lymphoma vs. IgG4-related DISEASE: 3D turbo field echo with diffusion-sensitised driven-equilibrium preparation technique.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined therapy of lapatinib and capecitabine effective against local recurrence of breast cancer2013

Author(s)

Journal Title

Data Source

[Journal Article] CHFR aberrant methylation involves a subset of human lung adenocarcinoma associated with poor clinical outcomes2013

Author(s)

Journal Title

Data Source

[Journal Article] Aurora-B overexpression is correlated with aneuploidy and poor prognosis in non-small cell lung cancer2013

Author(s)

Journal Title

DOI

Data Source

KOGA Takaomi 古賀孝臣