KOMATSU Toshimitsu 小松利光

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Komatsu Toshimitsu 小松利光

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Researcher Number	70380962
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(医学系), 技術職員
Affiliation (based on the past Project Information) *help	2021 – 2024: 長崎大学, 医歯薬学総合研究科(医学系), 技術職員 2016 – 2018: 長崎大学, 医歯薬学総合研究科(医学系), 技術職員 2014: 長崎大学, 医歯薬学総合研究科(医学系), 技術職員 2013: 長崎大学, 医歯(薬)学総合研究科, 技術職員 2012: 長崎大学, 医歯(薬)学総合研究科, 技術専門職員 … More 2012: 長崎大学, 医歯薬学総合研究科, 技術専門職員 2011: 長崎大学, 大学院・医歯薬学総合研究科, 技術職員 2010: 長崎大学, 医歯(薬)学総合研究科, 技術職員 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 59040:Nutrition science and health science-related / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator カロリー制限 / 肝臓 / 抗老化 / マクロファージ / NASH / 肝がん / 線維化 / Foxo3 / 非アルコール性脂肪肝炎 / 遺伝性疾患 … More / 寿命 / 代謝 / 老化 / 自己炎症性疾患 / WDR6 / 寿命延長 / マイクロアレイ解析 / ミトコンドリア / FoxO / 抗腫瘍効果 / 東洋医学 … More Except Principal Investigator 海洋微生物抽出物 / カロリー制限模倣剤 / 老化制御 Less

Search for compounds that mimic the effects of calorie restriction on healthy life extension and elucidation of mechanisms of the action
- Principal Investigator
  
  下川功
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki University
A mechanism underlying the inhibition of steatohepatitis via FoxO3Principal Investigator
- Principal Investigator
  
  Komatsu Toshimitsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki University
Analysis the aging mechanisms via WDR6 and aim for building new animal aging modelPrincipal Investigator
- Principal Investigator
  
  KOMATSU Toshimitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagasaki University
Identify FoxO1 and FoxO3a target genes that relate to anti-neoplastic effect and the anti-aging effect of calorie restrictionPrincipal Investigator
- Principal Investigator
  
  KOMATSU Toshimitsu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagasaki University
Research the possibility of the traditional Japanese medicine"Rikkunshito" as the calorie restriction mimetic drugPrincipal Investigator
- Principal Investigator
  
  KOMATSU Toshimitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagasaki University

All 2024 2011 2010

All Journal Article Presentation

[Journal Article] Acute stress response modified by modest inhibition of growth hormone axis: a potential machinery of the anti-aging effect of calorie restriction2011
- Author(s)
  Komatsu T, Trindade LS, et al
- Journal Title
  
  Mech Ageing Dev
  
  Volume: 132(3) Pages: 103-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790620
[Journal Article] Modest inhibition of the growth hormone axis does not affect mitochondrial reactive oxygen species geeration or redox state, unlike calorie restriction2011
- Author(s)
  Hayashida T, Komatsu T, et al
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 11(4) Pages: 496-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790620
[Journal Article] FoxO1 is involved in the antineoplastic effect of calorie restriction2010
- Author(s)
  Yamaza H, Komatsu T, et al
- Journal Title
  
  Aging Cell
  
  Volume: 9 Pages: 372-382
- NAID
  120006984942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790620
[Journal Article] Development of a bioassay to screen for chemicals mimicking theanti-aging effects of calorie restriction2010
- Author(s)
  Chiba T, Tsuchiya T, Komatsu T, et al
- Journal Title
  
  Curr Genomics
  
  Volume: 401(2) Pages: 213-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790620
[Journal Article] Development of calorie restriction mimietics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases2010
- Author(s)
  Chiba T, Tsuchiya T, Komatsu T, Mori R, Hayashi H, Shimokawa I
- Journal Title
  
  Curr Genomics
  
  Volume: 11(8) Pages: 562-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790620
[Presentation] 肝臓のFoxO3は加齢に伴う全身のエネルギー代謝とインスリン抵抗性を制御する2024
- Author(s)
  下川　功、小松　利光、朴　盛浚、森　亮一
- Organizer
  第１１３回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K11595
[Presentation] Does a traditional Japanese medicine "Rikkunshito" mimic effects of calorie restriction?2011
- Author(s)
  Yuko Nagatomi, Toshimitsu Komatsu
- Organizer
  The 1st Nagasaki-Pusan Joint seminar on aging Research
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-22790620
[Presentation] Does a traditional Japanese medicine "Rikkunshito" promote stress resistance like calorie restriction?2011
- Author(s)
  Taisuke Kasuya, Toshimitsu Komatsu
- Organizer
  The 1st Nagasaki-Pusan Joint seminar on aging Research
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-22790620

1. 下川功 (70187475)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 森亮一 (30509310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 千葉卓哉 (40336152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HAYASHI Hiroko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOMATSU Toshimitsu 小松 利光

Komatsu Toshimitsu 小松 利光

Research Projects

Research Products

Co-Researchers

Search for compounds that mimic the effects of calorie restriction on healthy life extension and elucidation of mechanisms of the action

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A mechanism underlying the inhibition of steatohepatitis via FoxO3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis the aging mechanisms via WDR6 and aim for building new animal aging modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identify FoxO1 and FoxO3a target genes that relate to anti-neoplastic effect and the anti-aging effect of calorie restrictionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research the possibility of the traditional Japanese medicine"Rikkunshito" as the calorie restriction mimetic drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acute stress response modified by modest inhibition of growth hormone axis: a potential machinery of the anti-aging effect of calorie restriction2011

Author(s)

Journal Title

Data Source

[Journal Article] Modest inhibition of the growth hormone axis does not affect mitochondrial reactive oxygen species geeration or redox state, unlike calorie restriction2011

Author(s)

Journal Title

Data Source

[Journal Article] FoxO1 is involved in the antineoplastic effect of calorie restriction2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Development of a bioassay to screen for chemicals mimicking theanti-aging effects of calorie restriction2010

Author(s)

Journal Title

Data Source

[Journal Article] Development of calorie restriction mimietics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases2010

Author(s)

Journal Title

Data Source

[Presentation] 肝臓のFoxO3は加齢に伴う全身のエネルギー代謝とインスリン抵抗性を制御する2024

Author(s)

Organizer

Data Source

[Presentation] Does a traditional Japanese medicine "Rikkunshito" mimic effects of calorie restriction?2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Does a traditional Japanese medicine "Rikkunshito" promote stress resistance like calorie restriction?2011

Author(s)

Organizer

Place of Presentation

Data Source

KOMATSU Toshimitsu 小松利光

Komatsu Toshimitsu 小松利光