Ohmori Tsukasa 大森司

… Alternative Names

OHMORI Tsukasa 大森司

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Researcher Number	70382843
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 自治医科大学, 医学部, 教授 2016 – 2021: 自治医科大学, 医学部, 教授 2014 – 2016: 自治医科大学, 医学部, 准教授 2007 – 2014: JICHI MEDICAL UNIVERSITY, School of Medicine, Assistant Prof. 2006: 自治医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Hematology / Basic Section 52010:General internal medicine-related / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology / Orthopaedic surgery / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 血友病 / iPS細胞 / 造血幹細胞 / 遺伝子診断 / ゲノム編集 / 第VIII因子 / 肝臓類洞内皮細胞 / 遺伝子治療 / 再生医療 / 血友病A … More / 血液凝固第VIII因子 / 造血幹細胞ニッチ / 転写因子 / 細胞周期 / Niche / 人工多能性幹細胞 / 遺伝子細胞治療 / 細胞骨格 / Talin / インテグリン / 造血幹細胞移植学 … More Except Principal Investigator 血友病 / 遺伝子治療 / 血友病A / 脊髄損傷 / 第VIII因子 / 免疫寛容 / インヒビター / カニクイザル / 生理活性脂質 / 第IX因子 / 細胞移植 / 血液凝固因子 / 凝固因子測定 / 脂質 / スフィンゴシン1リン酸 / SIV vector / adeno-associated virus vector / Factor IX / Factor VIII / Gene therapy / Hemophilia / 凝固VIII因 / 遣伝子治療 / 血小板 / 凝固IX因子 / 凝固VIII因子 / プラスミノーゲン / 線溶系 / 細胞療法 / 胸腺上皮細胞 / 細胞移植療法 / 人工多能性幹細胞 / gene therapy / hemophilia / 血友病Ａクローンブタ / アデノ随伴ウイルスベクター / 2次損傷 / スフィンゴシン1-リン酸 / アストロサイト / 血管透過性 / PAI-1欠損マウス / 第VIII因子欠損マウス / 第IX / 植え込み型マイクロポートシステム / マイクロポート / ノックアウトマウス / マイクロポートシステム Less

遺伝性疾患に対するiPS細胞とゲノム編集を用いた確実な遺伝子診断・個別化医療の創出Principal Investigator
- Principal Investigator
  
  大森司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Jichi Medical University
Development of a human coagulation factor assay using hemophilia A porcine plasma
- Principal Investigator
  
  Kashiwakura Yuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Jichi Medical University
Elucidation of the origin of blood coagulation factor VIII-producing cells for the development of new hemophilia treatmentPrincipal Investigator
- Principal Investigator
  
  Ohmori Tsukasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Jichi Medical University
Development of a novel therapeutic strategy for the treatment of spinal cord injury by modulating sphingosine 1-phoshate metabolism
- Principal Investigator
  
  Kimura Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Jichi Medical University
The role of Foxf1a for the function of hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Ohmori Tsukasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Role of fibrinolytic process in the functional recovery after contusion spinal cord injury
- Principal Investigator
  
  Kimura Atsushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Jichi Medical University
Development of novel thymus-directed strategy for central immune tolerance induction in hemophilia A
- Principal Investigator
  
  MADOIWA Seiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
次世代血友病治療法の開発と非ヒト霊長類を用いた前臨床研究
- Principal Investigator
  
  三室淳
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Application of iPSCs for hemophilia therapyPrincipal Investigator
- Principal Investigator
  
  OHMORI Tsukasa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Sphingosine 1-phosphate/S1P receptor axis as a molecular target for therapeutic intervention after spinal cord injury
- Principal Investigator
  
  KIMURA Atsushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Jichi Medical University
Regulation of plasminogen activator inhibitor-1 promotes the immune response to factor VIII in murine hemophilia A.
- Principal Investigator
  
  MADOIWA Seiji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Vinculin is indispensable for hematopoietic stem cell repopulationPrincipal Investigator
- Principal Investigator
  
  OHMORI Tsukasa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Preclinical Hemophilia Gene Therapy Study with Non-human Primates
- Principal Investigator
  
  MIMURO Jun
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Development of immune-tolerance induction by continuous infusion of FactorVIII using micro-injection system in murine hemophilia A
- Principal Investigator
  
  MADOIWA Seiji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Preclinical Study for Hemophilia Gene and Cell Therapy in Model Mice and in Non-human Primates
- Principal Investigator
  
  MIMURO Jun
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University

[Book] EBM血液疾患の治療2021-20222020
- Author(s)
  金倉　譲、木崎昌宏、鈴木律朗、神田善伸、大森　司、山崎宏人
- Total Pages
  637
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-18K08370
[Book] 血液疾患最新の治療2020-20222019
- Author(s)
  大森　司
- Total Pages
  390
- Publisher
  南江堂
- ISBN
  9784524249787
- Data Source
  KAKENHI-PROJECT-18K08370
[Book] 臨床に直結する血栓止血学2018
- Author(s)
  大森　司
- Total Pages
  9
- Publisher
  中外医学社
- ISBN
  4498125797
- Data Source
  KAKENHI-PROJECT-18K08370
[Book] Stem Cells and Cancer Stem Cells, volume 2 - Chapter 112011
- Author(s)
  Ohmori T, and Sakata Y
- Total Pages
  8
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23591427
[Book] Hematopoietic stem cell repopulation after transplantation.(Stem Cells and Cancer Stem Cells : Therapeutic Applications in Disease and Injury, Volume 2)
- Author(s)
  Ohmori T., Sakata Y.
- Publisher
  Springer(in press).
- Data Source
  KAKENHI-PROJECT-21790920
[Book] STEM CELLS AND CANCER STEM CELLS
- Author(s)
  Ohmori T, Sakata Y.
- Publisher
  Springer(印刷中)
- Data Source
  KAKENHI-PROJECT-21790920
[Journal Article] Non-viral ex vivo genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9.2021
- Author(s)
  Byambaa S, Uosaki H, Ohmori T, Hara H, Endo H, Nureki O, Hanazono Y.
- Journal Title
  
  Mol Ther Methods Clin Dev
  
  Volume: 20 Pages: 451-462
- DOI
  10.1016/j.omtm.2021.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07576, KAKENHI-PROJECT-19KK0219, KAKENHI-PROJECT-17K11248, KAKENHI-PROJECT-18K08370, KAKENHI-PROJECT-21K15872
[Journal Article] Establishment of a megakaryoblastic cell line for conventional assessment of platelet calcium signaling2020
- Author(s)
  Saito H, Hayakawa M, Kamoshita N, Yasumoto A, Suzuki-Inoue K, Yatomi Y, Ohmori T
- Journal Title
  
  Int J Hematol
  
  Volume: in press Issue: 6 Pages: 786-794
- DOI
  10.1007/s12185-020-02853-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Hemophilia gene therapy; New country initiatives2020
- Author(s)
  Reiss UM, Zhang L, Ohmori T
- Journal Title
  
  Haemophilia
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Altered behavior in mice overexpressing soluble ST22020
- Author(s)
  Motoshi Kikuchi, Kenkichi Takase, Morisada Hayakawa, Hiroko Hayakawa, Shin-Ichi Tominaga, Tsukasa Ohmori
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 74-84
- DOI
  10.1186/s13041-020-00606-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06473, KAKENHI-PROJECT-18K08370
[Journal Article] ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome2020
- Author(s)
  Watanabe Sachiko、Usui-Kawanishi Fumitake、Komada Takanori、Karasawa Tadayoshi、Kamata Ryo、Yamada Naoya、Kimura Hiroaki、Dezaki Katsuya、Ohmori Tsukasa、Takahashi Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 2 Pages: 125-132
- DOI
  10.1016/j.bbrc.2020.07.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K08524, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08370
[Journal Article] Successful treatment of hepatocellular carcinoma by laparoscopic radiofrequency ablation in a patient with hemophilia A2020
- Author(s)
  Goka Rie、Morimoto Naoki、Miura Kouichi、Watanabe Shunji、Takaoka Yoshinari、Nomoto Hiroaki、Tsukui Mamiko、Fujieda Takeshi、Maeda Hiroshi、Sato Naoto、Ohmori Tsukasa、Isoda Norio、Yamamoto Hironori
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 13 Issue: 5 Pages: 907-913
- DOI
  10.1007/s12328-020-01133-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Deletion of inflammasome adaptor protein ASC enhances functional recovery after spinal cord injury in mice2020
- Author(s)
  Shiraishi Yasuyuki、Kimura Atsushi、Kimura Hiroaki、Ohmori Tsukasa、Takahashi Masafumi、Takeshita Katsushi
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 20 Issue: 3 Pages: 30124-30124
- DOI
  10.1016/j.jos.2020.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370, KAKENHI-PROJECT-20K07365
[Journal Article] Utility of microminipigs for evaluating liver-mediated gene expression in the presence of neutralizing antibody against vector capsid2020
- Author(s)
  Watano R, Ohmori T, Hishikawa S, Sakata A, and Mizukami H.
- Journal Title
  
  Gene Therapy
  
  Volume: in press Issue: 9 Pages: 427-434
- DOI
  10.1038/s41434-020-0125-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Induction of IκBζ augments cytokine and chemokine production by IL-33 in mast cells.2020
- Author(s)
  Ohto-Ozaki H, Hayakawa M, Kamoshita N, Maruyama T, Tominaga S-I, Ohmori T
- Journal Title
  
  J Immunol.
  
  Volume: 204 Issue: 8 Pages: 2033-2042
- DOI
  10.4049/jimmunol.1900315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Hemophilia gene therapy?New country initiatives2020
- Author(s)
  Reiss Ulrike M.、Zhang Lei、Ohmori Tsukasa
- Journal Title
  
  Haemophilia
  
  Volume: 27 Issue: S3 Pages: 132-141
- DOI
  10.1111/hae.14080
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Development of a Unique T Cell Receptor Gene-Transferred Tax-Redirected T Cell Immunotherapy for Adult T Cell Leukemia2020
- Author(s)
  Kawamura Koji、Tanaka Yukie、Nakasone Hideki、Ishihara Yuko、Kako Shinichi、Kobayashi Seiichiro、Tanaka Yuetsu、Ohmori Tsukasa、Uchimaru Kaoru、Okamoto Sachiko、Mineno Junichi、Shiku Hiroshi、Nishimura Satoshi、Kanda Yoshinobu
- Journal Title
  
  Biology of Blood and Marrow Transplantation
  
  Volume: 26 Issue: 8 Pages: 1377-1385
- DOI
  10.1016/j.bbmt.2020.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07292, KAKENHI-PROJECT-18K08369, KAKENHI-PROJECT-18K08370
[Journal Article] 特集ゲノム編集技術の基礎と応用５.ゲノム編集とウイルスベクター2018
- Author(s)
  大森司
- Journal Title
  
  血液フロンティア
  
  Volume: 28 Issue: 7 Pages: 1053-1059
- DOI
  10.20837/52018071053
- ISSN
  1344-6940
- Year and Date
  2018-06-30
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Development of gene therapy for hemophilia: current states and future perspectives2018
- Author(s)
  大森司
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 10 Pages: 2238-2246
- DOI
  10.11406/rinketsu.59.2238
- NAID
  130007496694
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] 血友病の遺伝子治療2018
- Author(s)
  大森司
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 29 Issue: 6 Pages: 760-764
- DOI
  10.2491/jjsth.29.760
- NAID
  130007530651
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Safety of intra-articular transplantation of lentivirally transduced mesenchymal stromal cells for haemophilic arthropathy in a non-human primate2018
- Author(s)
  Ohmori Tsukasa、Mizukami Hiroaki、Katakai Yuko、Kawai Sho、Nakamura Hitoyasu、Inoue Makoto、Shu Tsugumine、Sugimoto Hideharu、Sakata Yoichi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 108 Issue: 3 Pages: 239-245
- DOI
  10.1007/s12185-018-2465-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Advances in gene therapy for hemophilia: basis, current status, and future perspectives2018
- Author(s)
  Ohmori Tsukasa
- Journal Title
  
  International Journal of Hematology
  
  Volume: E-pub Issue: 1 Pages: 31-41
- DOI
  10.1007/s12185-018-2513-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study.2014
- Author(s)
  Koyama, K., S. Madoiwa, S. Nunomiya, T. Koinuma, M. Wada, A. Sakata, T. Ohmori, J. Mimuro, and Y. Sakata.
- Journal Title
  
  Crit Care
  
  Volume: 18 Issue: 1
- DOI
  10.1186/cc13190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591430
[Journal Article] Paxillin is an intrinsic negative regulator of platelet activation in mice.2014
- Author(s)
  Sakata, A., T. Ohmori, S. Nishimura, H. Suzuki, S. Madoiwa, J. Mimuro, K. Kario, and Y. Sakata.
- Journal Title
  
  Thromb J
  
  Volume: 12 Issue: 1 Pages: 1-1
- DOI
  10.1186/1477-9560-12-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591430
[Journal Article] Production of functional coagulation factor VIII from iPSCs using a lentiviral vector2014
- Author(s)
  Kashiwakura Y, Ohmori T, Mimuro J, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y
- Journal Title
  
  Haemophilia
  
  Volume: 20
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Production of functional coagulation factor VIII from iPSCs using a lentiviral vector2014
- Author(s)
  Kashiwakura Y, Ohmori T, Mimuro J, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y.
- Journal Title
  
  Haemophilia
  
  Volume: 20 Issue: 1
- DOI
  10.1111/hae.12311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
[Journal Article] The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young Japanese individuals.2014
- Author(s)
  Mimuro J, Mizukami H, Shima M, Matsushita T, Taki M, Muto S, Higasa S, Sakai M, Ohmori T, Madoiwa S, Ozawa K, and Sakata Y.
- Journal Title
  
  J. Med. Virol.
  
  Volume: 86 Issue: 11 Pages: 1990-1997
- DOI
  10.1002/jmv.23818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430, KAKENHI-PROJECT-25461460
[Journal Article] Minimizing the Inhibitory Effect of Neutralizing Antibody for Efficient Gene Expression in the Liver With Adeno-associated Virus 8 Vectors2013
- Author(s)
  Mimuro J, Mizukami H, Hishikawa S, Ikemoto T, Ishiwata A, Sakata A, Ohmori T, Madoiwa S, Ono F, Ozawa K, Sakata Y
- Journal Title
  
  Mol Ther
  
  Volume: 21 Pages: 318-323
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Minimizing the inhibitory effect of neutralizing antibody for efficient gene expression in the liver with adeno-associated virus 8 vectors.2013
- Author(s)
  Mimuro J, Mizukami H, Hishikawa S, Ikemoto T, Ishiwata A, Sakata A, Ohmori T, Madoiwa S, Ono F, Ozawa K, and Sakata Y
- Journal Title
  
  Mol Ther
  
  Volume: 21 Issue: 2 Pages: 318-323
- DOI
  10.1038/mt.2012.258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
[Journal Article] 血友病aクローンブタ2013
- Author(s)
  柏倉裕志, 三室淳, 大西彰, 岩元正樹, 窓岩清治, 淵本大一郎, 鈴木俊一, 鈴木美佐枝, 千本昭一郎, 石渡彰, 安本篤史, 坂田飛鳥, 大森司, 橋本径子, 矢崎智子, 坂田洋一
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 24 Pages: 224-224
- Data Source
  KAKENHI-PROJECT-24591430
[Journal Article] Overexpression of factor VII ameliorates bleeding diathesis of factor VIII-deficient mice with inhibitors.2013
- Author(s)
  Yasumoto A, Madoiwa S, Kashiwakura Y, Ishiwata A, Ohmori T, Mizukami H. Ozawa K, Sakata Y, and Mimuro J.
- Journal Title
  
  Thromb. Res.
  
  Volume: 131 Issue: 5 Pages: 444-449
- DOI
  10.1016/j.thromres.2013.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
[Journal Article] Acquired factor v inhibitor associated with life-threatening bleeding and a mixing test result that indicated coagulation factor deficiency.2013
- Author(s)
  Ashizawa M, Kimura S, Wada H, Sakamoto K, Sato M, Terasako K, Kikuchi M, Nakasone H, Okuda S, Kako S, Yamazaki R, Oshima K, Matsuura K, Ohmori T, Madoiwa S, Nishida J, Mimuro J, Tabei K, Sakata Y, Kanda Y.
- Journal Title
  
  Hematology
  
  Volume: 18 Issue: 5 Pages: 300-304
- DOI
  10.1179/1607845412y.0000000072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591430
[Journal Article] Tissue plasminogen activator (tPA) deficiency promotes early phase regeneration in the olfactory epithelium after bulbectomy2013
- Author(s)
  Makino N, Madoiwa S, Ohmori T, Katoh K, Ookawara S, Kanazawa T, Matsuo O, Ichikawa M, Mimuro J, Ichimura K, Sakata Y
- Journal Title
  
  International Forum of Allergy & Rhinology
  
  Volume: 3 Issue: 6 Pages: 458-467
- DOI
  10.1002/alr.21124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570084, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-24591430
[Journal Article] Genetically modified adipose tissue-derived stem/stromal cells, using simian immunodeficiency virus-based lentiviral vectors, in the treatment of hemophilia B2013
- Author(s)
  Watanabe N, Ohashi K, Tatsumi K, Utoh R, Shim IK, Kanegae K, Kashiwakura Y, Ohmori T, Sakata Y, Inoue M, Hasegawa M, Okano T
- Journal Title
  
  Hum Gene Ther
  
  Volume: 24 Pages: 283-294
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Evaluation of hemostatic biomarker abnormalities that precede platelet count decline in critically ill patients with sepsis2013
- Author(s)
  Koyama, K., Madoiwa, S., Tanaka, S., Koinuma, T., Wada, M., Sakata, A., Ohmori, T., Mimuro, J., Nunomiya, S. and Sakata, Y.
- Journal Title
  
  J Crit Care
  
  Volume: in press Issue: 5 Pages: 556-563
- DOI
  10.1016/j.jcrc.2012.10.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591430
[Journal Article] Overexpression of factor VII ameliorates bleeding diathesis of factor VIII-deficient mice with inhibitors2013
- Author(s)
  Yasumoto A, Madoiwa S, Kashiwakura Y, Ishiwata A, Ohmori T, Mizukami H, Ozawa K, Sakata Y, Mimuro J
- Journal Title
  
  Thromb Res
  
  Volume: 131 Pages: 444-449
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012
- Author(s)
  Madoiwa, S., et al.
- Journal Title
  
  Haemophilia
  
  Volume: 18 Issue: 3
- DOI
  10.1111/j.1365-2516.2011.02686.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591249, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
[Journal Article] Intra-articular injection of mesenchymal stem cells expressing coagulation factorameliorates hemophilic arthropathy in factor VIII-deficient mice.2012
- Author(s)
  Kashiwakura, Y
- Journal Title
  
  J Thromb Haemost.
  
  Volume: 10(9) Issue: 9 Pages: 1802-1813
- DOI
  10.1111/j.1538-7836.2012.04851.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
[Journal Article] Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy2012
- Author(s)
  Ohmori, T., Yano, Y., Sakata, A., Ikemoto, T., Shimpo, M., Madoiwa, S., Katsuki, T., Mimuro, J., Shimada, K., Kario, K., et al
- Journal Title
  
  Thromb Res
  
  Volume: 129
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms2012
- Author(s)
  Norimatsu, Y., Ohmori, T., Kimura, A., Madoiwa, S., Mimuro, J., Seichi, A., Yatomi, Y., Hoshino, Y., and Sakata, Y
- Journal Title
  
  Am J Pathol
  
  Volume: 180 Pages: 1625-1635
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Porcine model of hemophilia a. PLoS One.2012
- Author(s)
  Kashiwakura Y
- Journal Title
  
  PLoS One.
  
  Volume: 7(11) Issue: 11 Pages: e49450-e49450
- DOI
  10.1371/journal.pone.0049450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
[Journal Article] FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms2012
- Author(s)
  Norimatsu Y, Ohmori T, Kimura A, Madoiwa S, Mimuro J, Seichi A, Yatomi Y, Hoshino Y, Sakata Y.
- Journal Title
  
  Am J Pathol
  
  Volume: 180(4) Issue: 4 Pages: 1625-35
- DOI
  10.1016/j.ajpath.2011.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591641, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
[Journal Article] Porcine model of hemophilia A2012
- Author(s)
  Kashiwakura Y, Mimuro J, Onishi A, Iwamoto M, Madoiwa S, Fuchimoto D, Suzuki S, Suzuki M, Sembon S, Ishiwata A, Yasumoto A, Sakata A, Ohmori T, Hashimoto M, Yazaki S, Sakata Y
- Journal Title
  
  PLoS One
  
  Volume: 7
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy2012
- Author(s)
  Ohmori, T., et al.
- Journal Title
  
  Thromb Res
  
  Volume: 129 Issue: 4 Pages: e36-e40
- DOI
  10.1016/j.thromres.2011.10.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591249, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
[Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012
- Author(s)
  Madoiwa S, Kobayashi E, Kashiwakura Y, Sakata A, Yasumoto A, Ohmori T, Mimuro J, Sakata Y
- Journal Title
  
  Haemophilia
  
  Volume: 18
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Intra-articular injection of mesenchymal stem cells expressing coagulation factor ameliorates hemophilic arthropathy in factor VIII-deficient mice2012
- Author(s)
  Kashiwakura Y, Ohmori T, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y
- Journal Title
  
  J Thromb Haemost
  
  Volume: 10 Pages: 1802-1813
- Data Source
  KAKENHI-PROJECT-23591427
[Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012
- Author(s)
  Madoiwa, S., Kobayashi, E., Kashiwakura, Y., Sakata, A., Yasumoto, A., Ohmori, T., Mimuro, J., and Sakata, Y
- Journal Title
  
  Haemophilia
  
  Volume: 18
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation2011
- Author(s)
  Madoiwa, S., Tanaka, H., Nagahama, Y., Dokai, M., Kashiwakura, Y., Ishiwata, A., Sakata, A., Yasumoto, A., Ohmori, T., Mimuro, J., et al
- Journal Title
  
  Thromb Res
  
  Volume: 127 Pages: 349-355
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Predictive blood coagulation markers for early diagnosis of venous thromboembolism after total knee joint replacement2011
- Author(s)
  Watanabe, H. Madoiwa, S. Sekiya, H. Nagahama, Y. Matsuura, S. Kariya, Y. Ohmori, T. Mimuro, J. Hoshino, Y. Hayasaka, S. Sakata, Y.
- Journal Title
  
  Thromb Res
  
  Volume: 128 Issue: 6 Pages: e137-e143
- DOI
  10.1016/j.thromres.2011.07.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427
[Journal Article] Local regulation of neutrophil elastase activity by endogenous alpha1-antitrypsin in lipopolysaccharide-primed hematological cells2011
- Author(s)
  Dokai, M., Madoiwa, S., Yasumoto, A., Kashiwakura, Y., Ishiwata, A., Sakata, A., Makino, N., Ohmori, T., Mimuro, J., and Sakata, Y
- Journal Title
  
  Thromb Res
  
  Volume: 128 Pages: 283-292
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Predictive blood coagulation markers for early diagnosis of venous thromboembolism after total knee joint replacement2011
- Author(s)
  Watanabe, H., Madoiwa, S., Sekiya, H., Nagahama, Y., Matsuura, S., Kariya, Y., Ohmori, T., Mimuro, J., Hoshino, Y., Hayasaka, S., et al
- Journal Title
  
  Thromb Res
  
  Volume: 128
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation.2011
- Author(s)
  Madoiwa, S. Tanaka, H. Nagahama, Y. Dokai, M. Kashiwakura, Y. Ishiwata, A. Sakata, A. Yasumoto, A. Ohmori, T. Mimuro, J. Sakata, Y.
- Journal Title
  
  Thromb Res
  
  Volume: 127 Issue: 4 Pages: 349-355
- DOI
  10.1016/j.thromres.2010.12.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427
[Journal Article] Local regulation of neutrophil elastase activity by endogenous alpha1-antitrypsin in lipopolysaccharide-primed hematological cells.2011
- Author(s)
  Dokai, M., Madoiwa, S., Yasumoto, A., Kashiwakura, Y., Ishiwata, A., Sakata, A., Makino, N., Ohmori, T., Mimuro, J., and Sakata, Y.
- Journal Title
  
  Thromb Res
  
  Volume: 128 Issue: 3 Pages: 283-292
- DOI
  10.1016/j.thromres.2011.04.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427
[Journal Article] Vinculin activates inside-out signaling of integrin alphaIIbbeta3 in Chinese hamster ovary cells2010
- Author(s)
  Ohmori, T., Kashiwakura, Y., Ishiwata, A., Madoiwa, S., Mimuro, J., Honda, S., Miyata, T., and Sakata, Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 323-328
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Impact of acute cellular rejection on coagulation and fibrinolysis biomarkers within the immediate post-operative period in pediatric liver transplantation2010
- Author(s)
  Mimuro, J., Mizuta, K., Kawano, Y., Hishikawa, S., Hamano, A., Kashiwakura, Y., Ishiwata, A., Ohmori, T., Madoiwa, S., Kawarasaki, H., et al
- Journal Title
  
  Pediatr Transplant
  
  Volume: 14 Pages: 369-376
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Vinculin activates inside-out signaling of integrin αIIbβ3 in Chinese hamster ovary cells.2010
- Author(s)
  Ohmori, T., Kashiwakura Y., Ishiwata A., Madoiwa S., Mimuro J., Honda S., Miyata T., Sakata Y.
- Journal Title
  
  Biophy Biochem Res Commun 400(3)
  
  Pages: 323-328
- Data Source
  KAKENHI-PROJECT-21790920
[Journal Article] Mutant macaque factor IX T262A:A tool for hemophilia B gene therapy studies in macaques.2010
- Author(s)
  Ishiwata A., Mimuro J., Mizukami H., Kashiwakura Y., Yasumoto A., Sakata A., Ohmori T., Madoiwa S., Ono F., Shima M., Yoshioka A., Ozawa K., Sakata Y.
- Journal Title
  
  Thromb Res 125(6)
  
  Pages: 533-537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells, in dependent of integrin function.2010
- Author(s)
  Ohmori, T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(41) Pages: 31763-31773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Vinculin activates inside-out signaling of integrin alphaIIbβ3 in Chinese hamster ovary cells.2010
- Author(s)
  Ohmori T., Kashiwakura Y., Ishiwata A,. Madoiwa S., Mimuro J., Honda S., Miyata T., Sakata Y.
- Journal Title
  
  Biochem Biophys Res Commun 400(3)
  
  Pages: 323-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] VINCULIN ACTIVATES INSIDE-OUT SIGNALING OF INTEGRIN ALPHAIIBBETA3 IN CHINESE HAMSTER OVARY CELLS2010
- Author(s)
  Ohmori T, Kashiwakura Y, Ishiwata A, Madoiwa S, Mimuro J, Honda S, Miyata T, Sakata Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400(3) Pages: 323-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790920
[Journal Article] Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice2010
- Author(s)
  Ishiwata, A., Mimuro, J., Mizukami, H., Kashiwakura, Y., Takano, K., Ohmori, T., Madoiwa, S., Ozawa, K., and Sakata, Y.
- Journal Title
  
  J Gene Med
  
  Volume: 11 Pages: 1020-1029
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells, independent of integrin function.2010
- Author(s)
  Ohmori, T.
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 31763-31773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Vinculin activates inside-out signaling of integrin alphaIIbbeta3 in Chinese hamster ovary cells.2010
- Author(s)
  Ohmori, T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 323-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Mutant macaque factor IX T262A : a tool for hemophilia B gene therapy studies in macaques2010
- Author(s)
  Ishiwata, A., Mimuro, J., Mizukami, H., Kashiwakura, Y., Yasumoto, A., Sakata, A., Ohmori, T., Madoiwa, S., Ono, F., Shima, M., et al
- Journal Title
  
  Thromb Res
  
  Volume: 125 Pages: 533-537
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Development of platelet-directed gene modification by lentiviral vector.2010
- Author(s)
  Ohmori, T.
- Journal Title
  
  Rinsho Ketsueki.
  
  Volume: 51(8) Pages: 625-631
- NAID
  10026630183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells, independent of integrin function.2010
- Author(s)
  Ohmori T., Kashiwakura Y., Ishiwata A., Madoiwa S., Mimuro J., Furukawa Y., Sakata Y.
- Journal Title
  
  J Biol Chem. 285(41)
  
  Pages: 31763-31773
- Data Source
  KAKENHI-PROJECT-21790920
[Journal Article] Development of platelet-directed gene modification by lentiviral vector.2010
- Author(s)
  Ohmori T., Madoiwa S., Mimuro J., Sakata Y.
- Journal Title
  
  Rinsho Ketsueki 51(8)
  
  Pages: 625-631
- NAID
  10026630183
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Impacto of acute cellular rejection on coagulation and f ibrinolysis biomarkers within the immediate post-operative reriod in pediatric liver transplantation.2010
- Author(s)
  Mimuro J., Mizuta K., Kawano Y., Hishikawa S., Hamano A., Kashiwakura Y., Ishiwata A., Ohmori T., Madoiwa S., Kawarasaki H., Sakata Y.
- Journal Title
  
  Pediatr Transplant 14(3)
  
  Pages: 369-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells, independent of integrin function.2010
- Author(s)
  Ohmori, T., Kashiwakura,Y., Ishiwata, A., Madoiwa,S., Mimuro,J., Furukawa, Y., Sakata, Y.
- Journal Title
  
  J Biol Chem 285(41)
  
  Pages: 31763-31773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] VINCULIN IS INDISPENSABLE FOR REPOPULATION BY HEMATOPOIETIC STEM CELLS, INDEPENDENT OF INTEGRIN FUNCTION2010
- Author(s)
  Ohmori T, Kashiwakura Y, Ishiwata A, Madoiwa S, Mimuro J, Furukawa Y, Sakata Y.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285(41) Pages: 31763-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790920
[Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells2010
- Author(s)
  Ohmori, T., Kashiwakura, Y., Ishiwata, A., Madoiwa, S., Mimuro, J., Furukawa, Y., and Sakata, Y
- Journal Title
  
  Vinculin is indispensable for repopulation by hematopoietic stem cells
  
  Volume: 285 Pages: 31763-31773
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Vinculin activates inside-out signaling of integrin alphaIIbβ3 in Chinese hamster ovary cells. Biochem Biophys Res Commun.2010
- Author(s)
  Ohmori, T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400(3) Pages: 323-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2009
- Author(s)
  Madoiwa S., Yamauchi T., Kobayashi E., Hakamata Y., Dokai M., Makino N., Kashiwakura Y., Ishiwata A., Ohmori T., Mimuro J., Sakata Y.
- Journal Title
  
  J Thromb Haemost 7(5)
  
  Pages: 811-824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2009
- Author(s)
  Madoiwa, S., Yamauchi, T., Kobayashi, E., Hakamata, Y., Dokai, M., Makino, N., Kashiwakura, Y., Ishiwata, A., Ohmori, T., Mimuro, J., et al
- Journal Title
  
  J Thromb Haemost
  
  Volume: 7 Pages: 811-824
- Data Source
  KAKENHI-PROJECT-21591249
[Journal Article] Liver-restricted expression of the canine factor VIII-gene facilitates prevention of inhibitor formation in factor VIII-deficient mice.2009
- Author(s)
  Ishiwata A., Mimuro J., Mizukami H., Kashiwakura Y., Takano K., Ohmori T., Madoiwa S., Ozawa K., Sakata Y.
- Journal Title
  
  J Gene Med 11(11)
  
  Pages: 1020-1029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2009
- Author(s)
  Madoiwa S, Yamauchi T, Kobayashi E, Hakamata Y, Dokai M, Makino N, Kashiwakura Y, Ishiwata A, Ohmori T, Mimuro J, Sakata Y.
- Journal Title
  
  J Thromb Haemost. 7
  
  Pages: 811-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Phenotypic correction of hemophilia A by ectopic expression of activated factor FVII in platelets.2008
- Author(s)
  Ohmori, T
- Journal Title
  
  Mol Ther. 2008. 16(8)
  
  Pages: 1359-1363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Phenotypic correction of hemophilia A by ectopic expression of activ ated factor FVII in platelets.2008
- Author(s)
  Ohmori, T
- Journal Title
  
  Mol Then. 2008. 16(8)
  
  Pages: 1359-1363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Dysfibrinogen Kagoshima with the amino acid substitution gammaThr-314 to Ile: analyses of molecular abnormalities and thrombophilic nature of this abnormal molecule.2008
- Author(s)
  Niwa K, Mimuro J, Miyata M, Sugo T, Ohmori T, Madoiwa S, Tei C, Sakata Y.
- Journal Title
  
  Thromb Res. 121
  
  Pages: 773-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Dysfibrinogen Kagoshima with the amino acid substitution gammaThr-314 to Ile: analyses of molecular abnormalities and thrombophilic nature of this abnormal molecule.2008
- Author(s)
  Niwa K, Mimuro J, Miyata M, Sugo T, Ohmori T, Madoiwa S, Tei C, Sakata Y.
- Journal Title
  
  Thromb Res. 124(1)
  
  Pages: 14-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Determinants of thrombbbbf thrombthrombof thrombthrombf thromb thrombrombrombhrombeneration, fibrinolytic activity, and endothelial dysfunction in dual-antiplatelet therapy : nvolvement of factors other than platelet aggregability in Virchow's triad.2008
- Author(s)
  Yano Y., Ohmori T., Hoshide S., Madoiwa S., Yamamoto K., Katsuki T., Mitsuhashi T., Mimuro J., Shimada K., Kario K., Sakata Y.
- Journal Title
  
  European Heart Journal Jul 29(14)
  
  Pages: 1729-1738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Phenotypic correction of hemophilia A by ectopic expression of activated factor VII in platelets.2008
- Author(s)
  Ohmori T, Ishiwata A, Kashiwakura Y, Madoiwa S, Mitomo K, Suzuki H, Hasegawa M, Mimuro J, Sakata Y.
- Journal Title
  
  Mol Ther. 16
  
  Pages: 1359-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain infarction.2008
- Author(s)
  Kimura.,A., Ohmori,T., Kashiwakura.Y., Ohkawa,R., Madoiwa,S., Mimuro,J., Shimazaki,K., Hoshino,Y., Yatomi,Y., Sakata,Y.
- Journal Title
  
  Stroke. Dec 39(12)
  
  Pages: 3411-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Unbalanced expression of ADAMTS13 and von Willebrand factor in mouse endotoxinemia.2008
- Author(s)
  Mimuro J, Niimura M, Kashiwakura Y, Ishiwata A, Ono T, Ohmori T, Madoiwa S, Okada K, Matsuo O, Sakata Y.
- Journal Title
  
  Thromb Res. 122
  
  Pages: 91-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Phenotypic orrection of hemophilia A by ectopic expression of activated factor FVII in platelets.2008
- Author(s)
  Ohmori,T., Ishiwata,A., Kashiwakura,Y., Madoiwa, S., Mitomo,K., Suzuki,H., Hasegawa,M., Mimuro,J.,Sakata,Y.
- Journal Title
  
  Mol Ther 16(8)
  
  Pages: 1359-1363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Determinants of thrombin generation, fibrinolytic activity, and endothelial dysfunction in patients on dual antiplatelet therapy: involvement of factors other than platelet aggregability in Virchow's triad.2008
- Author(s)
  Yano Y, Ohmori T, Hoshide S, Madoiwa S, Yamamoto K, Katsuki T, Mitsuhashi T, Mimuro J, Shimada K, Kario K, Sakata Y.
- Journal Title
  
  Eur Heart J. 29
  
  Pages: 1729-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Unbalanced expression of ADAMTS13 and von Willebrand factor in mouse2008
- Author(s)
  Mimuro J., Niimura M., Kashiwakura Y., Ishiwata A., Ono T., Ohmori T., Madoiwa S., Okada K., Matsuo O., Sakata Y.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591155
[Journal Article] Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain.2008
- Author(s)
  Kimura A, Ohmori T, Kashiwakura Y, Ohkawa R, Madoiwa S, Mimuro J, Shimazaki K, Hoshino Y, Yatomi Y, Sakata Y.
- Journal Title
  
  Stroke. 39
  
  Pages: 3411-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Silencing of a targeted protein in in vivo platelets using a lentiviral vectordelivering short hairpin RNA sequence.2007
- Author(s)
  Ohmori T
- Journal Title
  
  Arterioscler Thromb Vasc Bio1. 27(10)
  
  Pages: 2266-2272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Silencing of atargeted protein in invivo platelets using a lentiviral vector delivering short hairpin RNA sequenc2007
- Author(s)
  Ohmori T
- Journal Title
  
  Arterioscler Thromb Vasc Biol 27(10)
  
  Pages: 226-2272
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Silencing of a targeted protein in in vivo platelets using a lentiviral vectordelivering short hairpin RNA sequence.2007
- Author(s)
  Ohmori T, et. al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 27(10)
  
  Pages: 2266-2272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence.2007
- Author(s)
  Ohmori T, Kashiwakura Y, Ishiwata A, Madoiwa S, Mimuro J, Sakata Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 27
  
  Pages: 2266-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence2007
- Author(s)
  Ohmori, T
- Journal Title
  
  Arterioscler Thromb Vasc Biol 27(10)
  
  Pages: 2266-2272
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007
- Author(s)
  Madoiwa S, Someya T, Hironaka M, Kobayashi H, Ohmori T, Mimuro J, Sugiyama Y, Morita T, Nishimura Y, Tarumoto T, Ozawa K, Saito K, Sakata Y.
- Journal Title
  
  Thromb Res. 119
  
  Pages: 229-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.2007
- Author(s)
  Kimura A, Ohmori T, Ohkawa R, Madoiwa S, Mimuro J, Murakami T, Kobayashi E, Hoshino Y, Yatomi Y, Sakata Y.
- Journal Title
  
  Stem Cells. 25
  
  Pages: 115-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591133
[Journal Article] Efficient expression of a transgene in platelets using simian immunodeficiency virus-based vector harboring glycoprotein Ibalpha promoter : in vivo model for platelet-targeting gene therapy2006
- Author(s)
  Ohmori, T
- Journal Title
  
  FASEB J 20(9)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity : involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients2006
- Author(s)
  Ohmori, T
- Journal Title
  
  J. Thromb. Haemost 4
  
  Pages: 1271-127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Efficient expression of a transgene in platelets using simian immunodeficiency virus-based vector harboring glycoprotein Ibalpha promoter:in vivo model for platelet-targeting gene therapy2006
- Author(s)
  Ohmori T
- Journal Title
  
  FASEB J. 20(9)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Efficient expression of a tansgene in platelets using simian immunodeficiency virus-based vector harboring glycoprotein Ibalpha promoter : in vivo model for platelet-targeting gene therapy.2006
- Author(s)
  Ohmori T
- Journal Title
  
  FASEB J. 20(9)
  
  Pages: 1522-1524
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity : involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients.2006
- Author(s)
  Ohmori T
- Journal Title
  
  J.Thromb.Haemost (4)
  
  Pages: 1271-1278
- Data Source
  KAKENHI-PROJECT-18591084
[Journal Article] Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity:involvement of other signaling pathway(s)in cardiovascular events of aspirin-treated patients2006
- Author(s)
  Ohmori T
- Journal Title
  
  J.Thromb.Haemost 4
  
  Pages: 1271-1278
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591084
[Patent] 肝臓ゲノム上の凝固関連因子遺伝子を破壊するためのAAVベクター2017
- Inventor(s)
  大森　司、他
- Industrial Property Rights Holder
  学校法人自治医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-01-13
- Data Source
  KAKENHI-PROJECT-26461452
[Presentation] アデノ随伴ウイルスベクターをも用いた血友病に対する遺伝子治療2021
- Author(s)
  大森　司
- Organizer
  第20回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病に対する遺伝子治療の現状2021
- Author(s)
  大森　司
- Organizer
  第15回日本血栓止血学会学術標準化委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病の病態解明と治療への応用2020
- Author(s)
  大森　司
- Organizer
  第42回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] いちから学ぶ出血傾向2020
- Author(s)
  大森　司
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病に対する遺伝子治療とゲノム編集治療の進歩2019
- Author(s)
  大森　司
- Organizer
  第61回日本小児血液・がん学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] Adeno-associated virus vector based on serotype 3 represents an alternative serotype for hemophilia gene therapy2019
- Author(s)
  Ohmori, T., Mizukami, H., Hishikawa, S., Nakamura, H., Katakai, Y., Muramatsu, S., Ozawa, K., and Sakata, Y.
- Organizer
  Congress The International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病に対する遺伝子治療とゲノム編集治療2019
- Author(s)
  大森　司
- Organizer
  BioJapan2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] カニクイザルを用いた血友病性関節症に対する凝固因子発現間葉系幹細胞の安全性評価2019
- Author(s)
  大森　司，水上　浩明，片貝　祐子，川合　創，中村　仁康，井上　誠，朱　亜峰，杉本　英治，坂田　洋一
- Organizer
  第41回　日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病に対する遺伝子治療の展望2018
- Author(s)
  大森　司
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病に対するin vivoゲノム編集治療2018
- Author(s)
  大森　司
- Organizer
  第3回日本ゲノム編集学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] ゲノム編集による血友病治療の試み2018
- Author(s)
  大森　司
- Organizer
  創薬薬理フォーラム第26回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] Development of Genome editing treatment for Hemophilia2018
- Author(s)
  大森　司
- Organizer
  The 24th Annual Meeting of Japan Society of Gene and Cell Therapy
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] ゲノム編集技術による疾患治療戦略2018
- Author(s)
  大森　司
- Organizer
  日本小児神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] 血友病遺伝子治療の現状と展望2018
- Author(s)
  大森　司
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] CRISPR/Cas9-mediated Genome Editing for Hemophilia B by AAV vector2018
- Author(s)
  Tsukasa　Ohmori
- Organizer
  The 10th Congress of Asia Pacific Society on Thrombosis and Hemostasis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] CRISPR/Cas9-Mediated Genome Editing using an AAV8 Vector Improves Hemostasis in a Mouse Model of Hemophilia B in vivo2017
- Author(s)
  Ohmori T
- Organizer
  The 25thUS-Japan Cellular and Gene Therapy Conference
- Place of Presentation
  U.S. Food and Drug Administration（Silver Spring, MD, USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461452
[Presentation] 血友病遺伝子治療の現状と展望2016
- Author(s)
  大森　司
- Organizer
  第38回　日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良県・奈良市）
- Year and Date
  2016-06-16
- Invited
- Data Source
  KAKENHI-PROJECT-26461452
[Presentation] Forkhead box転写因子Foxf1aは血小板インテグリンの発現・機能に関与しない2016
- Author(s)
  大森　司、西村　智、富永　眞一
- Organizer
  平成28年度　日本生化学会関東支部例会
- Place of Presentation
  自治医科大学教育研究棟（栃木県・下野市）
- Data Source
  KAKENHI-PROJECT-26461452
[Presentation] 血友病治療をサイエンスから考える2016
- Author(s)
  大森　司
- Organizer
  日本血栓止血学会教育セミナー
- Place of Presentation
  クロスウエーブ梅田（大阪府・大阪市）
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26461452
[Presentation] Regulation of plasminogen activator inhibitor -1 promotes immune tolerance to factor VIII in murine hemophilia A.2013
- Author(s)
  Seiji Madoiwa, Tsukasa Ohmori, Toshio Miyata, Takashi Dan, Yuji Kashiwakura, Asuka Sakata, Jun Mimuro, Kiyotaka Okada, Shigeru Ueshima, Hitoshi Endo, Makoto Inoue, Mamoru Hasegawa, Osamu Matsuo, Keiya Ozawa, Yoichi Sakata
- Organizer
  2013 Congress of Internationl Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam, Netherland
- Data Source
  KAKENHI-PROJECT-24591430
[Presentation] 血友病Aクローンブタ2013
- Author(s)
  柏倉裕志、三室淳、大西彰、岩元正樹、窓岩清治、淵本大一郎、鈴木俊一、鈴木美佐枝、千本昭一郎、石渡彰、安本篤史、坂田飛鳥、大森司、橋本径子、矢崎智子、坂田洋一
- Organizer
  第35回日本血栓止血学会学術集会, (日本血栓止血学会誌)
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] REGULATION OF PLASMINOGEN ACTIVATOR INHIBITOR-1 REDUCES IMMUNE RESPONSE TO FACTOR VIII IN MURINE HEMOPHILIA A.2013
- Author(s)
  Seiji Madoiwa, Tsukasa Ohmori, Toshio Miyata, Takashi Dan, Yuji Kashiwakura, Asuka Sakata, Jun Mimuro, Kiyotaka Okada, Shigeru Ueshima, Hitoshi Endo, Makoto Inoue, Mamoru Hasegawa, Osamu Matsuo, Keiya Ozawa, Yoichi Sakata
- Organizer
  2013 East Asia Hemophilia Forum
- Place of Presentation
  Seoul, South Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24591430
[Presentation] Regulation of plasminogen activator inhibitor-1 promotes immune tolerance to factor VIII in murine hemophilia A2013
- Author(s)
  Madoiwa S, Ohmori T, Kashiwakura Y, Sakata A, Mimuro J, Sakata Y
- Organizer
  the XXIV Congress of the ISTH
- Place of Presentation
  Amsterdam, Netherland
- Data Source
  KAKENHI-PROJECT-24591430
[Presentation] Development of a cell-based therapy for treating hemophilic arthropathy by local injection of transduced MSCs2013
- Author(s)
  大森司
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] FVIII遺伝子導入MSCの関節内移植は血友病Aマウスの血友病性関節症を改善する2012
- Author(s)
  柏倉裕志,大森司,三室淳,安本篤史,石渡彰,坂田飛鳥,窓岩清治,井上誠,長谷川護,小澤敬也,坂田洋一
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] Dose-respnse relationship of factor IX expression in non-human orimates using AAV8-based vector2012
- Author(s)
  水上浩明、三室淳、塚原智典、卜部匡司、久米晃浩、大森司、窓岩清治、坂田洋一、小澤敬也
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] 第VIII因子感作血友病マウスにおけるマイクロポートを用いた連続的抗原投与モデルの構築2012
- Author(s)
  窓岩　清治，小林　英司，坂田　飛鳥，柏倉　裕志，大森　司，三室　淳，坂田　洋一
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms2012
- Author(s)
  Norimatsu Y, Ohmori T, Kimura A, Madoiwa S, Mimuro J, Seichi A, Yatomi Y, Hoshino Y, Sakata Y
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-22591641
[Presentation] スフィンゴシン 1-リン酸受容体を標的とした新しい脊髄損傷治療法の開発2012
- Author(s)
  乗松祐佐, 大森司, 木村敦, 星地亜都司, 坂田洋一, 星野雄一
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591641
[Presentation] 人工多能性幹細胞を用いた新規血友病治療法に対する基礎的検討2012
- Author(s)
  柏倉裕志、大森司、坂田飛鳥、窓岩清治、井上誠、長谷川護、三室淳、坂田洋一
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms2012
- Author(s)
  Norimatsu Y, Ohmori T, Kimura A, Madoiwa S, Mimuro J, Seichi A, Yatomi Y, Hoshino Y, Sakata Y
- Organizer
  The Orthopaedic Research Society (ORS)
- Place of Presentation
  San Francisco
- Year and Date
  2012-02-05
- Data Source
  KAKENHI-PROJECT-22591641
[Presentation] Intra-articular injection of autologous mesenchymal stem cells ameliorates hemophilic arthropathy in factor VIII-deficient mice2011
- Author(s)
  Kashiwakura Y, Ohmori T, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Watanabe N, Tatsumi K, Ohashi K, Okano T and Sakata Y
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] Application of lentiviral vectors to therapies for inherited bleeding disorders and research into blood cell signal transduction2011
- Author(s)
  Ohmori T
- Organizer
  Aso International Meeting(招待講演)
- Place of Presentation
  Kumamoto
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] Intra-articular injection of autologous mesenchymal stem cells ameliorates hemophilic arthropathy in factor VIII-deficient mice.2011
- Author(s)
  Y. Kashiwakura., T.,Ohmori., J. Mimuro., A.,Yasumoto., Akira,Ishiwata., A.,Sakata., S.Madoiwa., M.Inoue., M.,Hasegawa., N.,Watanabe.,K.Tatsumi., K.Ohashi., T.Okano., Y.Sakata
- Organizer
  ISTH2011.XXIII Congress of the International Society on Thrombosis and Haemostasis.
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23591426
[Presentation] Leukocyte elastase as an alternative pathway for fibrinolysis.2011
- Author(s)
  Seiji, Madoiwa., Hideyuki, Tanaka., Yutaka, Nagahama., Atsushi, Yasumoto., Asuka, Sakata., Yuji, Kashiwakura., Tsukasa, Ohmori., Jun, Mimuro., Yoichi, Sakata.
- Organizer
  57th Annual SSC Meetin
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23591426
[Presentation] Intra-articular injection of autologous mesenchymal stem cells ameliorates hemophilic arthropathy in factor VIII-deficient mice2011
- Author(s)
  Kashiwakura Y, Ohmori T, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Watanabe N, Tatsumi K, Ohashi K, Okano T, Sakata Y
- Organizer
  ISTH2011.XXIII Congress of the International Society on Thrombosis and Haemostasis.57^<th> Annual SSC Meeting
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] Silencing of A targeted protein in platelets using A lentiviral vector delivering short hairpin RNA sequence.2010
- Author(s)
  大森司,柏倉裕志, 石渡彰, 窓岩清治, 三室淳, 坂田洋一
- Organizer
  第16回日本遺伝子治療学会学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice.2010
- Author(s)
  Jun Mimuro, Akira Ishiwata, Hiroaki Mizukami, Yuji Kashiwakura, Katsuhiro Takano, Tsukasa Ohmori, Seiji Madoiwa, Keiya Ozawa, Yoichi Sakata
- Organizer
  第16回日本遺伝子治療学会学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Robust and sustained factor IX expression following IV injection of AAV8-based vectors in magaques.2010
- Author(s)
  水上浩明、三室淳、石渡彰、八木洋也、大森司、窓岩清治、卜部匡司、久米晃浩、坂田洋一、小澤敬也
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] レンチウィルスベクターを用いた血小板標的遺伝子導入法の開発(シンポジウム)2010
- Author(s)
  大森司、窓岩清治、三室淳、坂田洋一
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Successful factor IX expression by IV administration of AAV8 vectors in macaques.2010
- Author(s)
  Hiroaki Mizukami, Jun Mimuro, Akira Ishiwata, Hiroya Yagi, Tsukasa Ohmori, Masashi Urabe, Akihiro Kume, Yoichi Sakata, Keiya Ozawa
- Organizer
  第16回日本遺伝子治療学会学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Platelet-directed gene modification by lentiviral vector:Application to therapies for inherited bleeding disorders and research into platelet signal. シンポジウム2010
- Author(s)
  大森司、窓岩清治、三室淳、坂田洋一
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Impact ofacute cellular rejection onbiomarkers in liver transplantation2010
- Author(s)
  三室淳、水田耕一、川野陽一、菱川修司、浜野明栄、柏倉裕志、石渡彰、坂田飛鳥、安本篤史、大森司、窓岩清治、河原崎秀雄、坂田洋一
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] レンチウィルスベクターを用いた血小板標的遺伝子導入法の開発2010
- Author(s)
  大森司
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 非ヒト霊長類を用いた血友病B 遺伝子治療研究:末梢静脈投与AAV8 ベクターによる第IX 因子遺伝子導入2010
- Author(s)
  石渡彰、三室淳、水上浩明、小野文子、安本篤史、坂田飛鳥、柏倉裕志、大森司、窓岩清治、久米晃啓、保富康宏、小澤敬也、坂田洋一
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Promoter selection formuscle-directed self-complementary AAV toward hemophilia B gene therapy.2010
- Author(s)
  久米晃浩、八木洋也、水上浩明、卜部匡司、塚原智典、石渡彰、三室淳、窓岩清治、大森司、坂田洋一、小澤敬也
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Vinculin is indispensadle forrepopulation by hematopoietic stem cells.2010
- Author(s)
  Tsukasa Ohmori, Yuji Kashiwakura, Akira Ishiwata, Seiji Madoiwa, Jun Mimuro, Yusuke Furukawa, Yoichi Sakata
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Vinculin は巨核球分化とintegrin αIIb3 の活性化に関与する2010
- Author(s)
  大森司、柏倉裕志、石渡彰、坂田飛鳥、安本篤史、窓岩清治、三室淳、本田繁則、宮田敏行、坂田洋一
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Vinculin is indispensable for repopulation by hematopoietic stem cells.2010
- Author(s)
  Tsukasa, Ohmori.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] VINCULIN IS INDISPENSABLE FOR REPOPULATION BY HEMATOPOIETIC STEM CELLS2010
- Author(s)
  大森司
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790920
[Presentation] The chicken hypersensitive site-4 chromatin insulator sequence protects clonal domina of hematopoietic stem cells transduced with a self-inactivating SIV vector in platelet-directed gene therapy.2010
- Author(s)
  Tsukasa Ohmori, Yuji Kashiwakura, Akira Ishiwata, Seiji Madoiwa, Eiji Akiba, Mamoru Hasegawa, Jun Mimuro, Keiya Ozawa, Yoichi Sakata
- Organizer
  第16回日本遺伝子治療学会学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Vinculinは巨核球分化とintegrin αIIb3の活性化に関与する2010
- Author(s)
  大森司
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Vinculin is indispensable for repopulation by hematopoietic stem cells.2010
- Author(s)
  大森司, 柏倉裕志, 石渡彰, 窓岩清治, 三室淳, 古川雄佑, 坂田洋一
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790920
[Presentation] マイクロポート植え込み成体血友病 A マウスを用いた持続的第VIII 因子刺激に対する免疫応答能の解析2010
- Author(s)
  窓岩清治、小林英司、石渡彰、柏倉裕志、大森司、三室淳、坂田洋一
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Platelet-directed gene therapy for hemophilia by lentiviral vector.2010
- Author(s)
  Ohmori T., Sakata Y.
- Organizer
  The 6^<th> Congress of Asia Pacific Society on Thrombosis and Haemostasis(シンポジウム)
- Place of Presentation
  Nusa Dua Bali
- Data Source
  KAKENHI-PROJECT-21790920
[Presentation] Choice of small-sized promother for AAV-medlated factor IX expression in skeletal muscle.2010
- Author(s)
  Akihiro Kume, Hiroya Yagi, Hiroaki Mizukami, Masashi Urabe, Tomonori Tsukahara, Akira Ishiwata, Jun Mimuro, Seiji Madoiwa, Tsukasa Ohmori, Yoichi Sakata, Keiya Ozawa
- Organizer
  第16回日本遺伝子治療学会学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 非ヒト霊長類を用いた血友病A伝子治療研究に向けたヒトBDDFVIII特異的検出法の確立2010
- Author(s)
  柏倉裕志、三室淳、石渡彰、安本篤史、坂田飛鳥、大森司、窓岩清治、水上浩明、小野文子、小澤敬也、坂田洋一
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] GPIba 遺伝子近傍のクロマチンインスレーター配列の同定2009
- Author(s)
  大森司、青木慎也、Thasinas Dissayabutra、石渡彰、柏倉裕志、窓岩清治、秋葉栄治、長谷川護、三室淳、坂田洋一
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Platelet-directed gene modification by lentiviral vector.2009
- Author(s)
  大森司, 窓岩清治, 三室淳, 坂田洋一
- Organizer
  第71回日本血液学会学術集会(シンポジウム)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21790920
[Presentation] Platelet-directed gene modiffication by lentiviral vector2009
- Author(s)
  Tsukasa Ohmori
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21790920
[Presentation] Platelet-directed gene modification by lentiviral vector : Application to therapies for inherited bleeding disorders and research into platelet signal2009
- Author(s)
  大森司
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 高純度AAV8、AAV9 ベクター精製法ノ確立2009
- Author(s)
  石渡彰、三室淳、柏倉裕志、大森司、窓岩清治、水上浩明、久米晃啓、小澤敬也、坂田洋一
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 敗血症DICにおける血栓溶解機構のモニタリングとその臨床的意義2009
- Author(s)
  窓岩清治、田中英之、松浦司郎、大森司、三室淳、坂田洋一青木慎也
- Organizer
  第9回TTMフォーラム
- Place of Presentation
  東京
- Year and Date
  2009-03-07
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] 血小板への遺伝子発現増強を目的としたGPIba プロモーターの改変2009
- Author(s)
  Thasinas Dissayabutra、大森司、青木慎也、石渡彰、柏倉裕志、窓岩清治、秋葉栄治、長谷川護、三室淳、坂田洋一
- Organizer
  第32回日本血栓止血学会学術集
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 異常第VIII 因子遺伝子正常化による血友病A 遺伝子治療の試み2008
- Author(s)
  柏倉裕志, 三室淳, 石渡彰, 山中一央, 土海桃子, 青木慎也, 大森司, 窓岩清治, 坂田洋一
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] クロマチンインスレーター挿入による安全性を高めた血小板への遺伝子導入法2008
- Author(s)
  大森司
- Organizer
  第31回日本血栓止血学会学術集
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 血小板への活性化型血液凝固第VII因子の発現による血友病遺伝子治療2008
- Author(s)
  大森司
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] 非ヒト霊長類モデルにおける血友病B 遺伝子治療の基礎的検討2008
- Author(s)
  石渡彰, 三室淳, 水上浩明, 小野文子,柏倉裕志, 大森司, 諏合輝子, 窓岩清治, 保富康宏, 小澤敬也, 坂田洋一
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 血小板への活性化型血液凝固第VII因子の発現による血友病遺伝子治療2008
- Author(s)
  大森司
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Regulation of plasminogen activator - plasmin system and inflammation2008
- Author(s)
  Seiji Madoiwa, Takayuki Sejima, Jun Mimuro, Tsukasa Ohmori, Yoichi Sakata
- Organizer
  31st Congress of the Japanese Society on Thrombosis and Haemostasis (President Symposium)
- Place of Presentation
  Osaka, Japan
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] エンドトキシン症における血栓性微小血管障害の発症機序の解析2008
- Author(s)
  柏倉裕志, 三室淳, 新村真則, 小野智子, 石渡彰, 土海桃子, 大森司, 窓岩清治, 岡田清孝, 松尾理, 坂田洋一
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] クロマチンインスレーター挿入による安全性を高めた血小板への遺伝子導入法2008
- Author(s)
  大森司
- Organizer
  第31回日本血栓止血学会学術集
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] 血小板への活性化型血液凝固第VII 因子の発現による血友病遺伝子治療2008
- Author(s)
  大森司, 石渡彰, 柏倉裕志, 窓岩清治, 鈴木英紀, 見供克之, 長谷川護,三室淳, 坂田洋一
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] Regulation of plasminogen activator-plasmin system and inflammation.2008
- Author(s)
  窓岩清治, 三室淳, 大森司, 坂田洋一
- Organizer
  第31回日本血栓止血学会学術集会(シンポジウム)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591155
[Presentation] 敗血症DICにおける白血球エラスターゼによる血栓溶解機構の解析2008
- Author(s)
  窓岩清治,土海桃子,柏倉裕志,石渡彰,大森司,諏合輝子,三室淳,田中英之、松浦司郎,坂田洋一
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] レンチウィルスベクターを用いたshRNA発現による血小板蛋白のノックダウン2007
- Author(s)
  大森司
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  三重
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] 胸腺組織を標的とした血友病Aインヒビター産生制御の基礎的検討2007
- Author(s)
  窓岩清治,山内忠彦,小林英司,柏倉裕志,石渡彰,大森司,三室淳,坂田洋一
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Induction of Factor VIII Specific Unresponsiveness by Intrathymic Factor VIII Injection in Murine Hemophilia A.2007
- Author(s)
  Seiji Madoiwa, Tadahiko Yamauchi, Eiji Kobayashi, Yoji Hakamata, Yuji Kashiwakura, Akira Ishiwata, Tsukasa Ohmori, Jun Mimuro, Yoichi Sakata
- Organizer
  XXIst Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-08
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence2007
- Author(s)
  Ohmori, T
- Organizer
  The 30th Congress of Japanese Society on Thrombosis and Haemostasis
- Place of Presentation
  Shima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] PAI-1は敗血症DICの生命予後を規定する2007
- Author(s)
  窓岩清治,布宮伸,大森司,三室淳,坂田洋一
- Organizer
  第8回日本検査血液学会
- Place of Presentation
  福井
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] レンチウィルスベクターを用いたshRNA発現による血小板蛋白のノックダウン2007
- Author(s)
  大森司
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  三重
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Silencing of A targeted protein in in vivo platelets using A lentiviral vector delivering short hairpin RNA sequnce2007
- Author(s)
  Ohmori T
- Organizer
  XXI ISTH Congress(21回国際血栓止血学会)
- Place of Presentation
  ジュネーブ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] レンチウィルスベクターを用いたshRNA発現による血小板蛋白のノックダウン2007
- Author(s)
  大森司
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] フィブリン分解産物の標準化に向けて2007
- Author(s)
  窓岩清治,大森司,三室淳,坂田洋一,北島勲,岡田清孝,上嶋繁,松尾理,一瀬白帝,内山真一郎,朝倉英策,江口豊,浦野哲盟,山本晃士,桜井錠治、馬場光広
- Organizer
  日本血栓止血学会学術標準化委員会2007(シンポジウム)
- Place of Presentation
  東京
- Year and Date
  2007-02-17
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Annexin 2 mediated fibrinolysis induces fatal hemorrhagic disorder in transitional cell carcinoma with vascular intimal carcinomatosis.2007
- Author(s)
  Seiji Madoiwa, Tsukasa Ohmori, Jun Mimuro, Yoichi Sakata
- Organizer
  1st Japanese-Polish - German Joint Meeting on Coagulation and Fibrinolysis
- Place of Presentation
  Dresden, Germany
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Silencing of A targeted protein in in vivo platelets using A lentiviral vector delivering short hairpin RNA sequnce.2007
- Author(s)
  Ohmori T
- Organizer
  XXI ISTH Congress(21回国際血栓止血学会)
- Place of Presentation
  ジュネーブ(スイス)
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] Silencing of A targeted protein in in vivo platelets using A lentiviral vector delivering short hairpin RNA sequnce.2007
- Author(s)
  Ohmori T
- Organizer
  XXI ISTH Congress(21回国際血栓止血学会)
- Place of Presentation
  ジュネーブ(スイス)
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] プラスミノゲンは白血球の接着活性を制御し、敗血症における臓器障害を回避させる2007
- Author(s)
  窓岩清治,新村真則,土海桃子,柏倉裕志,石渡彰,牧野伸子,大森司,諏合輝子,三室淳,坂田洋一、岡田清孝,上嶋繁,松尾理
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  三重
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Silencing of A targeted protein in in vivo platelets using A lentiviral vector delivering short hairpin RNA sequnce2007
- Author(s)
  Ohmori, T
- Organizer
  XXI ISTH Congress
- Place of Presentation
  Geneva
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] 敗血症DICにおけるPAI-1と生命予後との関係2007
- Author(s)
  窓岩清治,布宮伸,小野智子,大森司,三室淳,坂田洋一
- Organizer
  第1回SIRS-DIC研究会
- Place of Presentation
  宇都宮
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19591133
[Presentation] Augmentation of platelet hemostatic function by forced expression of FVIIa2006
- Author(s)
  Ohmori, T
- Organizer
  The 30th Congress of Japanese Society on Thrombosis and Haemostasis
- Place of Presentation
  Utsunomiya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] 血液凝固VIIの発現による止血反応を強化した血小板の作成2006
- Author(s)
  大森司
- Organizer
  第29回日本血栓止血学会学術集会
- Place of Presentation
  宇都宮
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591084
[Presentation] Development of cell-based therapy for treating hemophilic arthropathy by local injection of transduced MSCs
- Author(s)
  Ohmori T, Kashiwakura Y, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形
- Invited
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] 血清パラオキソナーゼ活性は抗血小板薬投与下の凝集能と関連しない
- Author(s)
  大森　司
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591426
[Presentation] 血友病Aクローンブタ
- Author(s)
  柏倉裕志，三室　淳，大西　彰，岩本正樹，窓岩清治，渕本大一郎，鈴木俊一，鈴木美佐枝，千本昭一郎，石渡　彰，安本　篤，坂田飛鳥，大森　司，橋本経子，矢崎智子，坂田洋一
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23591427
[Presentation] Overexpression of factor VII ameliorates bleeding diathesis of FVIII-deficient mice with inhibitors
- Author(s)
  安本篤史、窓岩清治、柏倉裕志、石渡彰、大森司、水上浩明、小澤敬也、坂田洋一、三室淳
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591427

1. MADOIWA Seiji (70296119)

# of Collaborated Projects: 8 results

# of Collaborated Products: 96 results
2. MIMURO Jun (10221607)

# of Collaborated Projects: 4 results

# of Collaborated Products: 56 results
3. KOBAYASHI Eiji (00245044)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. KIMURA Atsushi (20364507)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. Kashiwakura Yuji (40382890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西村智 (80456136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 白石康幸 (50646338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 早川盛禎 (30326847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 長尾恭光 (80303874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鴨下信彦 (90302603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 木内英 (80338102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KIKUCHI Motoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小澤敬也

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 遠藤仁司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 高瀬堅吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 高橋将文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 木村博昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 唐澤直義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 渡邊幸子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 鎌田諒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 市川真澄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 小林誠一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 田中ゆきえ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohmori Tsukasa 大森 司

OHMORI Tsukasa 大森 司

Research Projects

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Co-Researchers

遺伝性疾患に対するiPS細胞とゲノム編集を用いた確実な遺伝子診断・個別化医療の創出Principal Investigator

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Elucidation of the origin of blood coagulation factor VIII-producing cells for the development of new hemophilia treatmentPrincipal Investigator

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The role of Foxf1a for the function of hematopoietic stem cellsPrincipal Investigator

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Application of iPSCs for hemophilia therapyPrincipal Investigator

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Vinculin is indispensable for hematopoietic stem cell repopulationPrincipal Investigator

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Ohmori Tsukasa 大森司

OHMORI Tsukasa 大森司