Kubo Hirohito 窪寛仁

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KUBO Hirohito 窪寛仁

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Researcher Number	70388362
Affiliation (Current)	2025: 大阪歯科大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2024: 大阪歯科大学, 歯学部, 准教授 2014 – 2023: 大阪歯科大学, 歯学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 脱分化脂肪細胞 / エクソソーム / 脂肪由来脱分化脂肪細胞 / 上顎洞底挙上術 / 軟骨細胞 / 天井培養 / エピガロカテキンガレート Except Principal Investigator RNA-seq / 骨再生 / 老化 / 細胞老化

上顎洞底挙上術の臨床応用に向けた脱分化脂肪細胞由来エクソソーム徐放化技術の開発Principal Investigator
- Principal Investigator
  
  窪寛仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka Dental University
New molecular mechanism of inhibition on bone regeneration evaluated using stress-induced aging model and RNA-seq analysis
- Principal Investigator
  
  本田義知
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka Dental University
Reconstruction of extensive mandibular bone defects using dedifferentiated adipocyte-derived exosomes.Principal Investigator
- Principal Investigator
  
  KUBO Hirohito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka Dental University
Translational study of dedifferentiated fat cells from the buccal fat pad / PRP complex in in mandibular regenerationPrincipal Investigator
- Principal Investigator
  
  Hirohito Kubo
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Osaka Dental University
Transportation research of dedifferentiated fat cells derived from the human buccal fat pad for maxillofacial cartilage regenerationPrincipal Investigator
- Principal Investigator
  
  KUBO Hirohito
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Osaka Dental University

All 2022 2021 2020 2019 2018 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Bone Regeneration by Dedifferentiated Fat Cells Using Composite Sponge of Alfa-Tricalcium Phosphate and Gelatin in a Rat Calvarial Defect Model2021
- Author(s)
  Tsumano Nobuhito、Kubo Hirohito、Imataki Rie、Honda Yoshitomo、Hashimoto Yoshiya、Nakajima Masahiro
- Journal Title
  
  Applied Sciences
  
  Volume: 11 Issue: 24 Pages: 11941-11941
- DOI
  10.3390/app112411941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10003, KAKENHI-PROJECT-20K10195
[Journal Article] Bone Regeneration Using Rat-Derived Dedifferentiated Fat Cells Combined with Activated Platelet-Rich Plasma2020
- Author(s)
  Nakano Kosuke、Kubo Hirohito、Nakajima Masahiro、Honda Yoshitomo、Hashimoto Yoshiya
- Journal Title
  
  Materials
  
  Volume: 13 Issue: 22 Pages: 5097-5097
- DOI
  10.3390/ma13225097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10003, KAKENHI-PROJECT-20K10195, KAKENHI-PROJECT-17K11770, KAKENHI-PROJECT-17K11864
[Journal Article] Chondrocyte differentiation of human buccal fat pad-derived dedifferentiated fat cells and adipose-derived stem cells using an atelocollagen sponge2015
- Author(s)
  Nishio A, Kubo H, Kishimoto N, Hashimoto Y,Kakudo K
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 49 Pages: 185-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26463033
[Presentation] Characterization of extracellular vesicles isolated from dedifferentiated fat cell’s conditioned media2022
- Author(s)
  Yusuke Nishiguchi, Mamoru Ueda, Hirohito Kubo, Yoshiya Hashimoto
- Organizer
  国際歯科材料会議 2022 第80回学術講演会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10195
[Presentation] αTCP/ゼラチンスポンジ複合体を足場とした脱分化脂肪細胞による骨再生の試み2021
- Author(s)
  妻野誠仁，中野宏祐，上田　衛，西口雄祐，窪　寛仁，中嶋正博
- Organizer
  第66回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10195
[Presentation] ラット頭蓋冠欠損モデルにおけるアルファリン酸三カルシウムとゼラチンの複合スポンジを用いた脱分化脂肪細胞による骨再生2021
- Author(s)
  妻野誠仁，窪寛仁，今滝梨江，本田義知，橋本典也，中嶋正博
- Organizer
  第19回日本再生歯科医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10195
[Presentation] ラット由来脱分化脂肪細胞と活性化多血小板血漿を用いた骨再生2020
- Author(s)
  中野宏祐，窪　寛仁，本田義知，橋本典也，中嶋正博
- Organizer
  第567回大阪歯科学会例会
- Data Source
  KAKENHI-PROJECT-20K10195
[Presentation] ビーグル犬脂肪組織からの脱分化脂肪細胞作製の試み2020
- Author(s)
  妻野誠仁，中野宏祐，本橋具和，長谷小町、窪　寛仁，中嶋正博
- Organizer
  第65回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10195
[Presentation] ラット脱分化脂肪細胞(DFATs)と活性化多血小板血漿(aPRP)を用いた骨芽細胞分化能と骨再生2020
- Author(s)
  中野宏祐，窪　寛仁，上田　衛，妻野誠仁，中嶋正博
- Organizer
  第65回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10195
[Presentation] ラット脱分化脂肪細胞(DFATs）と活性化多血小板血漿(aPRP)を用いた骨芽細胞分化能と骨再生2020
- Author(s)
  中野宏祐，窪　寛仁，上田　衛，妻野誠仁，中嶋正博
- Organizer
  第65回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11864
[Presentation] ラット由来脱分化脂肪細胞と活性化多血小板血漿を用いた骨再生2020
- Author(s)
  中野宏祐，窪　寛仁，本田義知，橋本典也，中嶋正博
- Organizer
  第567回大阪歯科学会例会
- Data Source
  KAKENHI-PROJECT-17K11864
[Presentation] ビーグル犬脂肪組織からの脱分化脂肪細胞作製の試み2020
- Author(s)
  妻野誠仁，中野宏祐，本橋具和，長谷小町、窪　寛仁，中嶋正博
- Organizer
  第65回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11864
[Presentation] 多血小板血漿（PRP）が脱分化脂肪細胞（DFAT）の増殖能と分化能に及ぼす影響2019
- Author(s)
  中野宏祐，上田衛，窪寛仁，疋田光波，妻野誠仁，藤井智子，本橋具和
- Organizer
  第64回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11864
[Presentation] 脱分化脂肪細胞（DFAT）と多血小板血漿（PRP）を用いた骨再生2018
- Author(s)
  中野宏祐、上田衛、窪　寛仁、藤井智子、本橋具和、大西祐一、中嶋正博、吉本　仁
- Organizer
  第63回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11864
[Presentation] Chondrocyte differentiation ability of dedifferentiated fat cells compared with adipose-derived stem cells derived from the human buccal fat pad2016
- Author(s)
  Kubo H, Nishio A, Miya Y, Hashimoto Y, Kishimoto N
- Organizer
  International Dental Materials Congress 2016
- Place of Presentation
  The Stones Hotel-Legian Bali (Bali, Indonesia)
- Year and Date
  2016-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26463033
[Presentation] アテロコラーゲンスポンジを用いたヒト頬脂肪体由来の脱分化脂肪細胞と脂肪幹細胞の軟骨分化2014
- Author(s)
  西尾謙宏，窪　寛仁，岸本直隆，橋本典也，覚道健治
- Organizer
  第545回大阪歯科学会
- Place of Presentation
  大阪歯科大学（大阪府、枚方市）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26463033
[Presentation] ヒト頬脂肪体のDFAT cellsとASCsの3次元培養による軟骨分化能の比較2014
- Author(s)
  西尾謙宏，窪　寛仁，覚道健治
- Organizer
  第59回日本口腔外科学会総会・学術大会
- Place of Presentation
  幕張メッセ（千葉県、千葉市）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26463033
[Presentation] Comparison of chondrocyte differentiation ability using three-dimensional culture in an atelocollagen sponge on dedifferentiated fat cells and adipose-derived stem cells from the human buccal fat pad.
- Author(s)
  Nishio A, Kubo H, Hashimoto Y, Kakudo K
- Organizer
  AAOMS 96th Annual Meeting, Scientific Sessions & Exhibition in Conjunction with the Japanese Society and Korean Association of Oral and Maxillofacial Surgeons.
- Place of Presentation
  Hawaii Convention Center (Honolulu, USA)
- Year and Date
  2014-09-08 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26463033

1. 橋本典也 (20228430)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. 本田義知 (90547259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 田中知成 (70585695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 南部隆之 (80367903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 城潤一郎 (60511243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kubo Hirohito 窪 寛仁

KUBO Hirohito 窪 寛仁

Research Projects

Research Products

Co-Researchers

上顎洞底挙上術の臨床応用に向けた脱分化脂肪細胞由来エクソソーム徐放化技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New molecular mechanism of inhibition on bone regeneration evaluated using stress-induced aging model and RNA-seq analysis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reconstruction of extensive mandibular bone defects using dedifferentiated adipocyte-derived exosomes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Translational study of dedifferentiated fat cells from the buccal fat pad / PRP complex in in mandibular regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transportation research of dedifferentiated fat cells derived from the human buccal fat pad for maxillofacial cartilage regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Bone Regeneration by Dedifferentiated Fat Cells Using Composite Sponge of Alfa-Tricalcium Phosphate and Gelatin in a Rat Calvarial Defect Model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bone Regeneration Using Rat-Derived Dedifferentiated Fat Cells Combined with Activated Platelet-Rich Plasma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chondrocyte differentiation of human buccal fat pad-derived dedifferentiated fat cells and adipose-derived stem cells using an atelocollagen sponge2015

Author(s)

Journal Title

Data Source

[Presentation] Characterization of extracellular vesicles isolated from dedifferentiated fat cell’s conditioned media2022

Author(s)

Organizer

Data Source

[Presentation] αTCP/ゼラチンスポンジ複合体を足場とした脱分化脂肪細胞による骨再生の試み2021

Author(s)

Organizer

Data Source

[Presentation] ラット頭蓋冠欠損モデルにおけるアルファリン酸三カルシウムとゼラチンの複合スポンジを用いた脱分化脂肪細胞による骨再生2021

Author(s)

Organizer

Data Source

[Presentation] ラット由来脱分化脂肪細胞と活性化多血小板血漿を用いた骨再生2020

Author(s)

Organizer

Data Source

[Presentation] ビーグル犬脂肪組織からの脱分化脂肪細胞作製の試み2020

Author(s)

Organizer

Data Source

[Presentation] ラット脱分化脂肪細胞(DFATs)と活性化多血小板血漿(aPRP)を用いた骨芽細胞分化能と骨再生2020

Author(s)

Organizer

Data Source

[Presentation] ラット脱分化脂肪細胞(DFATs）と活性化多血小板血漿(aPRP)を用いた骨芽細胞分化能と骨再生2020

Author(s)

Organizer

Data Source

[Presentation] ラット由来脱分化脂肪細胞と活性化多血小板血漿を用いた骨再生2020

Author(s)

Organizer

Kubo Hirohito 窪寛仁

KUBO Hirohito 窪寛仁