SHIOZAKI Kazuhiro 塩崎一弘

… Alternative Names

SIOZAKI Kazuhiro 塩崎一弘

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Researcher Number	70390896
Other IDs
Affiliation (Current)	2025: 鹿児島大学, 農水産獣医学域水産学系, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 鹿児島大学, 農水産獣医学域水産学系, 教授 2015 – 2023: 鹿児島大学, 農水産獣医学域水産学系, 准教授 2010 – 2014: 鹿児島大学, 水産学部, 助教 2009: 宮城県立がんセンター研究所, 博士研究員 2005 – 2008: 宮城県立がんセンター(研究所), 生化学部, 共同研究員
Review Section/Research Field	Principal Investigator Basic Section 40040:Aquatic life science-related / Aquatic life science / Fisheries chemistry Except Principal Investigator Biological Sciences / Experimental pathology / Basic Section 40030:Aquatic bioproduction science-related / Aquatic life science
Keywords	Principal Investigator シアリダーゼ / シアル酸 / 糖鎖 / 複合糖質 / メダカ / 核局在 / Neu4 / 核 / カラシン目 / Edardsiella tarda … More / Edwardsiella tarda / CMPシアル酸合成酵素 / シアル酸リアーゼ / 魚病 / Edwardsiela piscicida / モデル動物 / ゼブラフィッシュ / ゲノム編集 / リソソーム / 糖タンパク / 糖脂質 … More Except Principal Investigator シアリダーゼ / 遺伝子 / 糖鎖 / 酵素 / 癌 / がん治療 / 情報伝達 / siRNA / ガングリオシド / シアル酸 / 解凍 / 冷凍 / 海産ツボワムシ類 / 強通気 / 青色LED / 微細藻類 / ワムシ冷凍物 / 消化酵素活性 / Chaetoceros neogracile / Tisochrysis lutea / ニホンウナギ仔魚 / 植物プランクトン / 動物プランクトン / 微小口径仔魚 / ウナギ類仔魚 / デトリタス / 受容体 / 摂餌行動 / 神経生物学 / 感覚系 / c-fos / 脳 / トランスクリプトーム解析 / 味覚 / トランスクリプトーム / in situ hybridization / 最初期遺伝子 / ゴンズイ / cell adhesion / sialic acid / tumor-related antigen / gene / sialidase / sugar chain / enzyme / cancer / 接着 / 癌関連抗原 / 糖尿病 / 腫瘍 / アポトーシス / シグナル伝達 Less

Development of artificial detritus for feeding eel larvae and finfish larvae with quite small mouth
- Principal Investigator
  
  小谷知也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40030:Aquatic bioproduction science-related
- Research Institution
  Kagoshima University
Significance of glycoconjugate remodeling by fish sialidase localizing at nucleusPrincipal Investigator
- Principal Investigator
  
  塩崎一弘
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Kagoshima University
Remodeling of glycoconjugates in fish cells induced by the E. tarda infectionPrincipal Investigator
- Principal Investigator
  
  Kazuhiro Shiozaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Kagoshima University
Molecular and Cellular basis of pH sensitivity involved in feeding behavior of fish
- Principal Investigator
  
  Ikenaga Takanori
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Aquatic life science
- Research Institution
  Kagoshima University
Establishment of Neu1 knockout zebrafish by genome-editingPrincipal Investigator
- Principal Investigator
  
  Shiozaki Kazuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Aquatic life science
- Research Institution
  Kagoshima University
Physiological functions of fish glycoconjugates and their related enzymesPrincipal Investigator
- Principal Investigator
  
  Shiozaki Kazuhiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kagoshima University
Pathogenesis of cancer and diabetes caused by aberrant expression of sialidase
- Principal Investigator
  
  MIYAGI Taeko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Tohoku Pharmaceutical University
Molecular mechanism of regulation of cancer cell apoptosis by plasma membrane-associated sialidase
- Principal Investigator
  
  MIYAGI Taeko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  宮城県立がんセンター研究所
   Miyagi Cancer Center Research Institute
形質膜シアリダーゼによるがん細胞のアポトーシス制御機構
- Principal Investigator
  
  宮城妙子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Miyagi Cancer Center Research Institute
がんで異常亢進するシアリダーゼ遺伝子ノックダウンによるアポトーシス誘導機構
- Principal Investigator
  
  MIYAGI Taeko
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Miyagi Cancer Center Research Institute
Malignant alteration and its significance of a novel sialidase hydrolyzing mucins
- Principal Investigator
  
  MIYAGI Taeko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Miyagi Cancer Center Research Institute

[Book] Altered expression of sialidases in human cancer. Proceedings of the 9th ISCSM
- Author(s)
  Miyagi T., Takahashi K., Moriya S., Hata K., Wada T. Yamaguchi K., Shiozaki K
- Publisher
  Springer Publishers(in press)
- Data Source
  KAKENHI-PROJECT-22659082
[Journal Article] Enhancement of Edwardsiella piscicida infection, biofilm formation, and motility caused by N-acetylneuraminate lyase.2022
- Author(s)
  Vo, KL., Tran, TN., Kubo, Y., Sahashi, D., Komatsu, M., Shiozaki, K.
- Journal Title
  
  Glycoconj. J.
  
  Volume: - Issue: 3 Pages: 429-442
- DOI
  10.1007/s10719-022-10045-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06222, KAKENHI-PROJECT-19K06223
[Journal Article] Host lactosylceramide enhances Edwardsiella tarda infection.2021
- Author(s)
  Oishi, K., Morise, M., Vo, KL., Tran, TN., Sahashi, D., Ueda-Wakamatsu, R., Nishimura, W., Komatsu, M., Shiozaki, K.
- Journal Title
  
  Cellular Microbiology
  
  Volume: 23 Issue: 9
- DOI
  10.1111/cmi.13365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06222, KAKENHI-PROJECT-19K06223
[Journal Article] Identification of novel fish sialidase genes responsible for KDN-cleaving activity2020
- Author(s)
  Shiozaki Kazuhiro、Uezono Keiya、Hirai Go、Honda Akinobu、Minoda Masaya、Wakata Ryuta
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 37 Issue: 6 Pages: 745-753
- DOI
  10.1007/s10719-020-09948-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06223, KAKENHI-PROJECT-18H02097
[Journal Article] Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b2020
- Author(s)
  Honda Akinobu、Chigwechokha Petros Kingstone、Takase Ryo、Hayasaka Oki、Fujimura Koji、Kotani Tomonari、Komatsu Masaharu、Shiozaki Kazuhiro
- Journal Title
  
  Gene
  
  Volume: 742 Pages: 144538-144538
- DOI
  10.1016/j.gene.2020.144538
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06223
[Journal Article] Establishment and characterization of Neu1-knockout zebrafish and its abnormal clinical phenotypes2020
- Author(s)
  Okada Keiji、Takase Ryo、Hamaoka Yurie、Honda Akinobu、Ikeda Asami、Hokazono Yoichiro、Maeda Yutaro、Hayasaka Oki、Kotani Tomonari、Komatsu Masaharu、Shiozaki Kazuhiro
- Journal Title
  
  Biochemical Journal
  
  Volume: 477 Issue: 15 Pages: 2841-2857
- DOI
  10.1042/bcj20200348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06223
[Journal Article] Functional Characterization of Fish Sialidases and Their Diversity among Different Orders2019
- Author(s)
  塩﨑一弘、大石一樹、本田晃伸
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 31 Issue: 178 Pages: J7-J14
- DOI
  10.4052/tigg.1518.1J
- NAID
  130007556931
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2019-01-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J06604, KAKENHI-PROJECT-16K07876
[Journal Article] Functional Characterization of Fish Sialidases and Their Diversity among Different Orders2019
- Author(s)
  Shiozaki, K., Oishi, K., Honda, A.
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 31 Issue: 178 Pages: E7-E13
- DOI
  10.4052/tigg.1518.1E
- NAID
  130007556927
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J06604, KAKENHI-PROJECT-16K07876
[Journal Article] Desialylation by Edwardsiella tarda is the initial step in the regulation of its invasiveness2019
- Author(s)
  Vo Linh Khanh、Tsuzuki Toshiharu、Kamada-Futagami Yuko、Chigwechokha Petros Kingstone、Honda Akinobu、Oishi Kazuki、Komatsu Masaharu、Shiozaki Kazuhiro
- Journal Title
  
  Biochemical Journal
  
  Volume: 476 Issue: 21 Pages: 3183-3196
- DOI
  10.1042/bcj20190367
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06223, KAKENHI-PROJECT-17J06604
[Journal Article] Biological and Pathological Roles of Ganglioside Sialidases2018
- Author(s)
  Miyagi, T., Takahashi, K., Yamamoto, K., Shiozaki, K., Yamaguchi, K
- Journal Title
  
  Prog. Mol. Biol. Transl. Sci
  
  Volume: in press Pages: 121-150
- DOI
  10.1016/bs.pmbts.2017.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07876, KAKENHI-PROJECT-15K06848
[Journal Article] Unique nuclear localization of Nile tilapia (Oreochromis niloticus) Neu4 sialidase is regulated by nuclear transport receptor importin alpha/beta2018
- Author(s)
  Honda, A., Chigwechokha, P., Kamada-Futagami, Y., Komatsu, M., Shiozaki, K
- Journal Title
  
  Biochimie
  
  Volume: 142 Pages: 94-104
- DOI
  10.1016/j.biochi.2018.04.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07876
[Journal Article] Adjuvant effect of recombinant interleukin-12 in the Nocardiosis formalin-killed vaccine of the amberjack Seriola dumerili2017
- Author(s)
  Matsumoto, M., Araki, K., Hayashi, K., Takeuchi, Y., Shiozaki, K., Suetake, H., Yamamoto, A
- Journal Title
  
  Fish Shellfish Immunol
  
  Volume: 67 Pages: 263-269
- DOI
  10.1016/j.fsi.2017.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07876, KAKENHI-PROJECT-17J06515
[Journal Article] Suppression of Neu1 sialidase delays the absorption of yolk sac in medaka (Oryzias latipes) accompanied with the accumulation of alpha 2-3 sialo-glycoproteins.2017
- Author(s)
  Sena Ryuzono, Ryo Takase, Yuko Kamada, Takanori Ikenaga, Petros Kingstone Chigwechokha, Masaharu Komatsu, Kazuhiro Shiozaki
- Journal Title
  
  Biochmie
  
  Volume: 135 Pages: 63-71
- DOI
  10.1016/j.biochi.2017.01.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07875, KAKENHI-PROJECT-16K07876, KAKENHI-PROJECT-17K07943
[Journal Article] Naringenin suppresses Edwardsiella tarda infection in GAKS cells by NanA sialidase inhibition2017
- Author(s)
  Shinyoshi S., Y. Kamada, K. Matsusaki, P.K. Chigwechokha, S. Tepparin, K. Araki, M. Komatsu, K. Shiozaki
- Journal Title
  
  Fish Shellfish Immunol.
  
  Volume: 61 Pages: 86-92
- DOI
  10.1016/j.fsi.2016.12.018
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04984, KAKENHI-PROJECT-16K07875, KAKENHI-PROJECT-16K07876
[Journal Article] Overexpression of Carboxylesterase Contributes to the Attenuation of Cyanotoxin Microcystin-LR Toxicity2017
- Author(s)
  Shota Takumi, Tai Shimono, Satoshi Ikema, Yuki Hotta, Petros Kingstone Chigwechokha, Kazuhiro Shiozaki, Yasumasa Sugiyama, Mitsuru Hashimoto, Tatsuhiko Furukawa, Masaharu Komatsu
- Journal Title
  
  Comparative Biochemistry and Phyisiology part-C
  
  Volume: 194 Pages: 22-27
- DOI
  10.1016/j.cbpc.2017.01.008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07875, KAKENHI-PROJECT-16K07876, KAKENHI-PROJECT-26860445, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16K09115
[Journal Article] Positive regulation of myoblast differentiation by medaka Neu3b sialidase through ganglioside desialylation2016
- Author(s)
  Shiozaki, K., Harasaki, Y., Fukuda, M., Yoshinaga, A., Ryuzono, S., Chigwechokha, P., Komatsu M., Miyagi, T.
- Journal Title
  
  Biochimie
  
  Volume: 123 Pages: 65-72
- DOI
  10.1016/j.biochi.2016.01.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24780204, KAKENHI-PROJECT-16K07875
[Journal Article] Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human.2016
- Author(s)
  Ryuzono, S., Takase, R., Oishi, K., Ikeda, A., Chigwechokha, P., Funahashi, A., Komatsu, M., Miyagi, T., Shiozaki, K.,
- Journal Title
  
  Gene
  
  Volume: 575 Issue: 2 Pages: 513-523
- DOI
  10.1016/j.gene.2015.09.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24780204, KAKENHI-PROJECT-16K07875
[Journal Article] Recombinant sialidase NanA (rNanA) cleaves alpha2-3 linked sialic acid of host cell surface N-linked glycoprotein to promote Edwardsiella tarda infection2015
- Author(s)
  Chigwechokha, P.K., M. Tabata, S. Shinyoshi, K. Oishi, K. Araki, M. Komatsu, T. Itakura, K. Shiozaki
- Journal Title
  
  Fish and Shellfish Immunology
  
  Volume: 47 Issue: 1 Pages: 34-45
- DOI
  10.1016/j.fsi.2015.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450305, KAKENHI-PROJECT-24780204, KAKENHI-PROJECT-25292129
[Journal Article] Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase.2014
- Author(s)
  Shiozaki K, Ryuzono S, Matsushita N, Ikeda A, Takeshita K, Chigwechokha PK, Komatsu M, Miyagi T.
- Journal Title
  
  Fish Physiol Biochem.
  
  Volume: 40 Issue: 5 Pages: 1461-1472
- DOI
  10.1007/s10695-014-9940-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580304, KAKENHI-PROJECT-24780204
[Journal Article] Nile Tilapia Neu3 sialidases: molecular cloning, functional characterization and expression in Oreochromis niloticus.2014
- Author(s)
  Chigwechokha PK, Komatsu M, Itakura T, Shiozaki K.
- Journal Title
  
  Gene
  
  Volume: 15 Issue: 1 Pages: 155-164
- DOI
  10.1016/j.gene.2014.09.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580304, KAKENHI-PROJECT-24780204
[Journal Article] Molecular cloning and biochemical characterization of two novel Neu3 sialidases, neu3a and neu3b, from medaka (Oryzias latipes)2013
- Author(s)
  Shiozaki K, Takeshita K, Ikeda M, Ikeda A, Harasaki Y, Komatsu M, Yamada S, Yamaguchi K, Miyagi T
- Journal Title
  
  Biochimie
  
  Volume: 95 Issue: 2 Pages: 280-289
- DOI
  10.1016/j.biochi.2012.09.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592471, KAKENHI-PUBLICLY-24110514, KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-24580304, KAKENHI-PROJECT-24780204
[Journal Article] Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase2012
- Author(s)
  Yamaguchi, K., Shiozaki, K., Moriya, S., Koseki, K., Wada, T., Tateno, H., Sato, I., Asano, M., Iwakura, Y., and Miyagi, T.
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 7 Pages: e41132-e41132
- DOI
  10.1371/journal.pone.0041132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300142, KAKENHI-PROJECT-23650629, KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-24780204, KAKENHI-PUBLICLY-24110514
[Journal Article] Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU42011
- Author(s)
  Shiozaki, K., Yamaguchi, K., Takahashi, K., MoriyaS., Miyagi, T
- Journal Title
  
  J. Biol Chem
  
  Volume: 286 Pages: 21052-21061
- Data Source
  KAKENHI-PROJECT-22659082
[Journal Article] Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU42011
- Author(s)
  Shiozaki, K., et al
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 21052-21061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659082
[Journal Article] Regulation of plasma membrane-associated sialidase NEU3 gene by Sp1/Sp3 transcription factors2010
- Author(s)
  Yamaguchi, K., Koseki, K., Shiozaki, M., Shimada, Y., Wada, T., Miyagi, T
- Journal Title
  
  Biochem, J
  
  Volume: 430 Pages: 107-117
- Data Source
  KAKENHI-PROJECT-22659082
[Journal Article] Regulation of plasma membrane-associated sialidase NEU3 gene by Sp1/Sp3 transcription factors2010
- Author(s)
  Yamaguchi, K., Koseki, K., Shiozaki, M., Shimada, Y., Wada, T., Miyagi, T.
- Journal Title
  
  Biochem, J. (in press)
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Developmental change of sialidase NEU4 expression in murine brain and its involvement in the regulation of neuronal cell differentiation2009
- Author(s)
  Shiozaki K, Koseki K, Yamaguchi K, Shiozaki M, Narimatsu H, Miyagi T.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 21157-21164
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Plasma membrane -associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice2009
- Author(s)
  Shiozaki K., et al.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 588-594
- NAID
  10025143974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta 42009
- Author(s)
  Uemura, T, Shiozaki, K., Yamaguchi, K., Miyazaki, S., Satomi, S., Kato, K., Sakuraba, H., Miyagi, T.
- Journal Title
  
  Oncogene 28
  
  Pages: 1218-1229
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Developmental change of sialidase NEU4 expression in murine brain and its involvement in the regulation of neuronal cell differentiation2009
- Author(s)
  Shiozaki, K.et al.
- Journal Title
  
  J.Biol.Chem. 284巻
  
  Pages: 21157-21164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Plasma membrane-associated sialidase(NEU3)promotes formation ofcolonic aberrant crypt foci in azoxymethane-treated transgenic mice2009
- Author(s)
  Shiozaki K., et al.
- Journal Title
  
  Cancer Sci 100巻
  
  Pages: 588-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Plasma membrane -associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice2009
- Author(s)
  Shiozaki, K., Yamaguchi, K., Sato, I., Miyagi, T.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 588-594
- NAID
  10025143974
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Minireview, Plasma membrane - associated sialidase as a crucial regulator of transmenbrane signaling2008
- Author(s)
  Miyagi, T., Wada, T., Yamaguchi, K., Hata, H., Shiozaki, K.
- Journal Title
  
  J. Biochem 144
  
  Pages: 79-285
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] Human sialidase as a cancer marker2008
- Author(s)
  Miyagi, T., Wada T., Yamaguchi, K., Shiozaki, K., Sato, I., Yamanami, H., Kakugawa, Y., Fujiya, T.
- Journal Title
  
  Proteomics 8
  
  Pages: 3303-3311
- Data Source
  KAKENHI-PROJECT-20013047
[Journal Article] A crucial role of plasma membrane-associated sialidase (NEU3) in the survival of human cancer cells.2007
- Author(s)
  Wada, T., Hata, K., Yamaguchi, K., Shiozaki, K., Koseki, K., Moriya, S., Miyagi, T.
- Journal Title
  
  Oncogene 26
  
  Pages: 2483-2490
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390119
[Journal Article] Down-regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers.2006
- Author(s)
  Yamanami, T., Shiozaki, K., Wada, T., Yamaguchi, K., Uemura, T., Kakugawa, Y., Fujiya T., Miyagi, T.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 299-307
- NAID
  10019481340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390119
[Journal Article] Evidence for Mitochondrial Localization of a Novel Human Sialidase (NEU4).2005
- Author(s)
  Yamaguchi, T., Hata, K., Koseki, K., Shiozaki, K., Akita, H., Wada, T., Moriya, S., Miyagi, T.
- Journal Title
  
  Biochem.J. 390
  
  Pages: 85-93
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390119
[Presentation] A novel virulence factor: NanA sialidase and significance of the sialic acid metabolism in Edwardsiella tarda infection.2020
- Author(s)
  Vo, L., Shiozaki, K
- Organizer
  長崎大学-鹿児島大学・研究科学生交流ミニシンポジウム
- Data Source
  KAKENHI-PROJECT-19K06223
[Presentation] Edwardsiella tarda感染時における宿主シアリダーゼの発現変化とその意義.2020
- Author(s)
  佐橋大地、大石一樹、Vo Khanh Linh、二神（鎌田）裕子、小松正治、塩崎一弘
- Organizer
  43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06223
[Presentation] KDN加水分解活性を表す魚類シアリダーゼ分子種の同定.2020
- Author(s)
  塩崎一弘、本田晃伸、上薗慶也、平井剛
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K06223
[Presentation] 魚類リソソームでのシアル酸分解におけるbeta-galactosidaseの存在意義.2019
- Author(s)
  濱岡百合絵、岡田圭司、外園瑛一朗、小松正治、塩崎一弘
- Organizer
  令和元年度日本水産学会九州支部大会
- Data Source
  KAKENHI-PROJECT-19K06223
[Presentation] A novel virulence factor: NanA sialidase and significance of the sialic acid metabolism in Edwardsiella tarda infection.2019
- Author(s)
  Vo Khanh Linh 、都築利治、鎌田（二神）裕子、大石一樹、佐橋大地、小松正治、塩崎一弘
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K06223
[Presentation] CRISPR/Cas9を用いたNeu1KOゼブラフィッシュの作出とその表現型解析2018
- Author(s)
  岡田圭司、高瀬　諒、前田悠太郎、小松正治、塩崎一弘
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] メダカNeu3aによるガングリオシド組成の変化は魚類肝臓細胞のトリグリセリド蓄積量を減少させる2018
- Author(s)
  大石一樹、小松正治、塩崎一弘
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] 魚類における各局在型シアリダーゼの分布とその局在メカニズム2018
- Author(s)
  本田晃伸、二神裕子、小松正治、塩崎一弘
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] ティラピアNeu4は核に局在する新奇シアリダーゼである2018
- Author(s)
  本田晃伸、二神裕子、小松正治、塩崎一弘
- Organizer
  平成30年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] ゴンズイのc-fos遺伝子のクローニングと発現解析2018
- Author(s)
  山田大智，塩崎一弘，加藤太一郎，清原貞夫，池永隆徳
- Organizer
  平成30年度日本水産学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K07943
[Presentation] ゲノム改変ゼブラフィッシュを用いたヒト病態モデルの開発2017
- Author(s)
  塩崎一弘
- Organizer
  第4回鹿児島の黒膳機能性食と健康シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] シアリドーシスモデルとしてのneu1ノックアウトゼブラフィッシュの作製2017
- Author(s)
  高瀬　諒、前田悠太郎、小松正治、塩崎一弘
- Organizer
  平成29年度日本水産学会九州支部会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] Desialylation of ganglioside regulates triglyceride accumulation in fish liver2017
- Author(s)
  Oishi, K., Miyazaki, M., Nishimura, W., Komatsu, M., Shiozaki, K
- Organizer
  The JSFS 85th Anniversary-Commemorative International Symposium“Fisheries Science for Future Generations”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] Characterization of tilapia sialidases and its significance in bacterial infection2017
- Author(s)
  Honda, A., Chigwechokha, KP., Wakamatsu, R., Kamada, Y., Komatsu, M., Shiozaki, K.
- Organizer
  The JSFS 85th Anniversary-Commemorative International Symposium“Fisheries Science for Future Generations”,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] ImportinによるティラピアシアリダーゼNeu4の核局在制御機構2017
- Author(s)
  本田晃伸、Petros Kingstone Chigwechikha、鎌田裕子、小松正治、塩崎一弘
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] Edwardsiella tardaの病原性決定におけるNanAシアリダーゼの重要性2017
- Author(s)
  塩崎一弘、都築利治、Vo Khanh Linh、鎌田裕子、小松正治
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] 胚発生におけるリソソームシアリダーゼNeu1、Neu4の重要性2016
- Author(s)
  塩崎一弘、龍薗せな、高瀬　諒、鎌田裕子、大石一樹、宮崎未奈、小松正治、池永隆徳
- Organizer
  平成28年度日本水産学会秋季大会
- Place of Presentation
  近畿大学農学部（奈良県奈良市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K07876
[Presentation] 魚類肝臓におけるシアリダーゼNeu1の意義2015
- Author(s)
  高瀬　諒、龍薗せな、若松麗菜、Petros Kingstone Chigwechokha、本田晃伸、荒木亨介、小松正治、塩崎一弘
- Organizer
  平成27年度日本水産学会九州支部会
- Place of Presentation
  宮崎大学（宮崎県宮崎市）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] 魚類オートファジーにおける糖タンパク質分解の活性化機構とその重要性2015
- Author(s)
  龍薗せな、高瀬　諒、大石一樹、小松正治、塩崎一弘
- Organizer
  平成27年度日本水産学会九州支部会
- Place of Presentation
  宮崎大学（宮崎県宮崎市）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] メダカリソソームシアリダーゼの胚発生における意義2015
- Author(s)
  龍薗せな、高瀬諒、大石一樹、小松正治、宮城妙子、塩崎一弘
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] 魚類リソソームにおける脱シアリル化機構の解明とその意義2015
- Author(s)
  龍薗せな、高瀬諒、大石一樹、池田麻美、舟橋亜希、小松正治、塩崎一弘
- Organizer
  平成27年度日本水産学会秋季大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] 魚類ガングリオシドシアリダーゼNeu3aの形質膜局在機構2015
- Author(s)
  大石一樹、小松正治、塩崎一弘
- Organizer
  平成27年度日本水産学会秋季大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] Molecular cloning and characterization of gaglioside specific sialidase in tilapia2014
- Author(s)
  Chigwechokha, P., Itakura T., Komatsu, M., Shiozaki, K
- Organizer
  平成26年度日本水産学会秋季大会
- Place of Presentation
  九州大学（福岡県福岡市）
- Year and Date
  2014-09-21
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] ニホンメダカOryzias latipesのシアリダーゼ研究におけるモデル動物としての有用性2014
- Author(s)
  龍薗せな、池田麻美、原崎裕介、大石一樹、小松正治、宮城妙子、塩崎一弘
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] 筋分化におけるメダカシアリダーゼNeu3bの機能解析2014
- Author(s)
  原崎裕介、池田麻美、龍薗せな、吉川みのり、大石一樹、小松正治、塩崎一弘
- Organizer
  平成26年度日本水産学会秋季大会
- Place of Presentation
  九州大学（福岡県福岡市）
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] メダカシアリダーゼneu4の遺伝子クローニングおよび胚発生における発現解析2013
- Author(s)
  塩崎一弘、龍薗せな、池田麻美、原崎裕介、福田みどり、小松正治、宮城妙子
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪（大阪国際交流センター）
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] メダカシアリダーゼneu3a、neu3bの神経細胞分化に与える影響2012
- Author(s)
  竹下一輝,　池田麻美,　原崎裕介,　松下直人,　小松正治,　山田章二,　宮城妙子,　塩崎一弘
- Organizer
  平成24年度日本水産学会秋季大会
- Place of Presentation
  下関
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] メダカシアリダーゼneu3a、neu3bの性状解析とその生理的役割の検討2012
- Author(s)
  塩崎一弘,　竹下一輝,　池田麻美,　原崎裕介,　小松正治,　山田章二,　宮城妙子
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24780204
[Presentation] Altered expression of sialidases in human cancer2011
- Author(s)
  Miyagi, T., Takahashi, K., Moriya, S., Hata, K., Wada, T., Yamaguchi, K., Shiozaki, K
- Organizer
  IXth International Symposium(IXth ISCSM, 2011) on "Biochemical Roles of Eukaryotic Cell Surface Macromolecules"
- Place of Presentation
  Trivandrum, India
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-22659082
[Presentation] Distinct functional roles between ganglioside sialidases Neu3 and Neu42011
- Author(s)
  Miyagi, T., Yamaguchi, K., Shiozaki, K., Takahashi, K., Wada, T., Hata, K., Moriya, S., Yamamoto, K
- Organizer
  The 31st Naito Conference : Glycan Expression and Regulation[II]: Metabolites, Stress Response, Microdomains, and Beyond
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-22659082
[Presentation] A.possible mechanism of NEU3 activation at plasma membrane.2008
- Author(s)
  Shiozaki, K., et al.
- Organizer
  BMB 2008(第81回日本生化学会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20013047
[Presentation] NEU3 possibly interacts with EGFR at cytoplasmic side of plasma membrane.2008
- Author(s)
  Shiozaki, M., et al.
- Organizer
  BMB 2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20013047
[Presentation] Crucial roles of plasma membrane-associated sialidase in human cancer2008
- Author(s)
  Miyagi, T., Wada, T., Yamaguchi, K, Hata, K., Shiozaki, K.
- Organizer
  13th World Congress on advances in Oncology
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-20013047
[Presentation] Activation of Met receptor-derived signaling by plasma membrane-associated sialidase (NEU3).2008
- Author(s)
  Shiozaki, K., et al.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20013047

1. MIYAGI Taeko (50006110)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. SATO Ikurou (50225918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HATA Keiko (60390895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. TATENO Hiroo (70004744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Ikenaga Takanori (50553997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 清原貞夫 (50117496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 小谷知也 (30389069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 江幡恵吾 (10325772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石川学 (60284915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAGUCHI Kazunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 和田正

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 川村貞文

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐藤雅美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ARAKI Kyousuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. Takumi Shota

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小松正治

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
17. 浅野雅秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIOZAKI Kazuhiro 塩崎 一弘

SIOZAKI Kazuhiro 塩崎 一弘

Research Projects

Research Products

Co-Researchers

Development of artificial detritus for feeding eel larvae and finfish larvae with quite small mouth

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Significance of glycoconjugate remodeling by fish sialidase localizing at nucleusPrincipal Investigator

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Remodeling of glycoconjugates in fish cells induced by the E. tarda infectionPrincipal Investigator

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Molecular and Cellular basis of pH sensitivity involved in feeding behavior of fish

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Establishment of Neu1 knockout zebrafish by genome-editingPrincipal Investigator

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Physiological functions of fish glycoconjugates and their related enzymesPrincipal Investigator

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Pathogenesis of cancer and diabetes caused by aberrant expression of sialidase

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Molecular mechanism of regulation of cancer cell apoptosis by plasma membrane-associated sialidase

Principal Investigator

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形質膜シアリダーゼによるがん細胞のアポトーシス制御機構

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がんで異常亢進するシアリダーゼ遺伝子ノックダウンによるアポトーシス誘導機構

Principal Investigator

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Malignant alteration and its significance of a novel sialidase hydrolyzing mucins

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[Book] Altered expression of sialidases in human cancer. Proceedings of the 9th ISCSM

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[Journal Article] Enhancement of Edwardsiella piscicida infection, biofilm formation, and motility caused by N-acetylneuraminate lyase.2022

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SHIOZAKI Kazuhiro 塩崎一弘

SIOZAKI Kazuhiro 塩崎一弘