Shimizu Akira 清水晶

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SHIMIZU Akira 清水晶

清水晶シミズアキラ

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Researcher Number	70396638
Other IDs
Affiliation (Current)	2025: 金沢医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 金沢医科大学, 医学部, 教授 2021 – 2023: 金沢医科大学, 医学部, 教授 2019 – 2020: 群馬大学, 医学部附属病院, 講師 2013 – 2015: 群馬大学, 医学部附属病院, 講師 2007: Gunma University, 大学院・医学系研究科, 助教 2006: 群馬大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Dermatology / Virology
Keywords	Principal Investigator ヒト乳頭腫ウイルス / 爪部ボーエン病 / レトロトランスポゾン / ウイルス / ウイルス感染 / メチル化 / インターフェロン / 皮膚筋炎 / LINE-1 / condyloma … More / Bowen's disease / squamous cell carcinoma / human papillomavirus / 免疫不全 / 多発性疣贅 / 新規HPVクローニング / ボーエン病 / 皮膚腫瘍 / Human papillomavirus / 遺伝性疾患 / 皮膚科学 Less

粘膜型ハイリスクHPVによる爪部ボーエン病の発症機序と感染経路の解明Principal Investigator
- Principal Investigator
  
  清水晶
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kanazawa Medical University
粘膜悪性型HPV感染による爪部ボーエン病発症機序と新たなHPV感染経路の解明Principal Investigator
- Principal Investigator
  
  清水晶
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kanazawa Medical University
Elevated type I interferon expression in dermatomyositis: involvement of LINE-1 and viral infection.Principal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kanazawa Medical University
  Gunma University
Detection of human papillomaviruses in skin tumors and investigation of the pathgenesisPrincipal Investigator
- Principal Investigator
  
  Shimizu Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Gunma University
レトロウイルス以外のRNAウイルスもヒト細胞内で逆転写されるPrincipal Investigator
- Principal Investigator
  
  清水晶
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Gunma University

All 2023 2021 2020 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Visual Dermatology2013
- Author(s)
  清水　晶
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] The synchronized gene expression of retrotransposons and type I interferon in dermatomyositis.2021
- Author(s)
  Kuriyama Y, Shimizu A, Kanai S, Oikawa D, Tokunaga F, Tsukagoshi H, Ishikawa O.
- Journal Title
  
  Journal of American Academy of Dermatology
  
  Volume: 84 Issue: 4 Pages: 1103-1105
- DOI
  10.1016/j.jaad.2020.05.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K08766, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-21H02688
[Journal Article] Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease2021
- Author(s)
  Kuriyama Yuko、Shimizu Akira、Kanai Saki、Oikawa Daisuke、Motegi Sei-ichiro、Tokunaga Fuminori、Ishikawa Osamu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 23146-23146
- DOI
  10.1038/s41598-021-02522-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08766, KAKENHI-PROJECT-21K20753, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276
[Journal Article] Expression of ER stress markers (GRP78/BiP and PERK) in adenoid cystic carcinoma.2016
- Author(s)
  Kaira K, Toyoda M, Shimizu A, Shino M, Sakakura K, Takayasu Y, Takahashi K, Asao T, Chikamatsu K.
- Journal Title
  
  Acta Otolaryngol
  
  Volume: 136 Issue: 1 Pages: 1-7
- DOI
  10.3109/00016489.2015.1083120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10798, KAKENHI-PROJECT-26462547, KAKENHI-PROJECT-26670736, KAKENHI-PROJECT-25461683, KAKENHI-PROJECT-25861525
[Journal Article] Acquired epidermodysplasia verruciformis associated with human papillomavirus type 47 in a HIV-infected patient2016
- Author(s)
  Atsuko Ashida, Akira Shimizu, Ryuhei Okuyama
- Journal Title
  
  J Dermatol
  
  Volume: 印刷中 Issue: 6 Pages: 53-56
- DOI
  10.1111/1346-8138.13262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461687, KAKENHI-PROJECT-25461683, KAKENHI-PROJECT-26461686
[Journal Article] Distinct activation mechanisms of NF-κB regulator IKK by isoforms of the cell death regulator cFLIP.2016
- Author(s)
  Baratchian M, Davis CA, Shimizu A, Escors D, Bagneris C, Barrett T, Collins MK.
- Journal Title
  
  J Biol Chem.
  
  Volume: in press Issue: 14 Pages: 7608-7620
- DOI
  10.1074/jbc.m116.718122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Prognostic significance of thymidylate synthase (TS) expression in cutaneous malignant melanoma.2016
- Author(s)
  Shimizu A, Kaira K, Yasuda M, Asao T, and Ishikawa O.
- Journal Title
  
  Neoplasma
  
  Volume: 63(2) Pages: 282-7
- DOI
  10.4149/215_150714n389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Keratotic condyloma acuminatum.2016
- Author(s)
  Shimizu A, Hattori M, Kaira K, Ishikawa O.
- Journal Title
  
  J Dermatol.
  
  Volume: in press Issue: 6 Pages: 716-717
- DOI
  10.1111/1346-8138.13266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Generalized keratosis pilaris-like eruptions in a chronic myelogenous leukemia patient treated with nilotinib.2016
- Author(s)
  Shimizu A, Hattori M, Takeuchi Y, Ishikawa O.
- Journal Title
  
  J Dermatol.
  
  Volume: in press Issue: 9 Pages: 1100-1101
- DOI
  10.1111/1346-8138.13336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Erythema induratum in a patient with pulmonary Mycobacterium avium infection.2016
- Author(s)
  Hattori M, Shimizu A, Hisada T, Fukumoto T, Ishikawa O.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: in press Issue: 5 Pages: 705-706
- DOI
  10.2340/00015555-2348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Prognostic significance of GRP78/BiP expression in patients with Stage III/IV hypopharyngeal squamous cell carcinoma.2016
- Author(s)
  Kaira K, Toyoda M, Shimizu A, Imai H, Sakura K, Nikkuni O, Suzuki M, Iijima M, Asao T, ChikamatsuK.
- Journal Title
  
  Neoplasma
  
  Volume: in press Issue: 03 Pages: 588-94
- DOI
  10.4149/319_151002n513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683, KAKENHI-PROJECT-15K10798
[Journal Article] Decreased expression of class III β-tubulin is associated with unfavorable prognosis in patients with malignant melanoma.2016
- Author(s)
  Shimizu A, Kaira K, Yasuda M, Asao T, and Ishikawa O.
- Journal Title
  
  Melanoma Research
  
  Volume: in press Issue: 1 Pages: 29-34
- DOI
  10.1097/cmr.0000000000000208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Prognostic significance of β2-adrenergic receptor expression in malignant melanoma.2015
- Author(s)
  Shimizu A, Kaira K, Mori K, Kato M, Shimizu K, Yasuda M, Takahashi A, Oyama T, Asao T, and Ishikawa O.
- Journal Title
  
  Tumor biology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Detection of human papillomavirus type 67 in subungual Bowen’s disease presenting as longitudinal melanonychia.2015
- Author(s)
  Shimizu A, Yasuda M, Hoshijima K, Kato M, Takahashi A, Tamura A, Ishikawa O.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: 95 Issue: 6 Pages: 745-746
- DOI
  10.2340/00015555-2054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in cutaneous melanoma.2015
- Author(s)
  Shimizu A, Kaira K, Kato M, Yasuda M, Takahashi A, Tominaga H, Oriuchi N, Nagamori S, Kanai Y, Oyama T, Asao T, Ishikawa O.
- Journal Title
  
  Melanoma Res.
  
  Volume: 25 Issue: 5 Pages: 399-405
- DOI
  10.1097/cmr.0000000000000181
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461895, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-25461683, KAKENHI-PROJECT-25461801
[Journal Article] Successful treatment of lichen spinulosus with topical adapalene.2015
- Author(s)
  Uehara A, Abe M, Shimizu A, Motegi SI, Amano H, Ishikawa O.
- Journal Title
  
  Eur J Dermatol.
  
  Volume: 25(5) Issue: 5 Pages: 490-1
- DOI
  10.1684/ejd.2015.2597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] A novel autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response.2015
- Author(s)
  Madoka Kato, Akira Shimizu, Yoko Yokoyama, Kyoichi Kaira, Yutaka Shimomura, Akemi Ishida-Yamamoto, Kiyoko Kamei, Fuminori Tokunaga, and Osamu Ishikawa
- Journal Title
  
  J. Invest. Dermatol.
  
  Volume: 135 Issue: 5 Pages: 1253-1260
- DOI
  10.1038/jid.2015.12
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117006, KAKENHI-PROJECT-24591620, KAKENHI-PROJECT-25670137, KAKENHI-PUBLICLY-15H01172, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-25461683
[Journal Article] A case of familial Michelin tire baby syndrome.2015
- Author(s)
  Kato M, Shimizu A, Ishikawa O.
- Journal Title
  
  J Dermatol
  
  Volume: 42 Issue: 5 Pages: 534-6
- DOI
  10.1111/1346-8138.12826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Detection of human papillomavirus (HPV) in patients with squamous cell carcinoma and the clinical characteristics of HPV-positive cases2014
- Author(s)
  Shimizu A, Kato M, Takeuchi Y, Sano T, Kaira K, Uezato H, Ishikawa O
- Journal Title
  
  Br J Dermatol
  
  Volume: 171 Issue: 4 Pages: 779-785
- DOI
  10.1111/bjd.13234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460411, KAKENHI-PROJECT-25461683
[Journal Article] Pigmented condyloma acuminatum.2014
- Author(s)
  Shimizu A, Kato M, Ishikawa O.
- Journal Title
  
  Journal of Dermatology
  
  Volume: 41 Issue: 4 Pages: 337-339
- DOI
  10.1111/1346-8138.12428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Bowenoid papulosis successfully treated with imiquimod 5% cream.2014
- Author(s)
  Shimizu A, Kato M, Ishikawa O.
- Journal Title
  
  J Dermatol.
  
  Volume: 41 Pages: 545-546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Detection of Human Papillomavirus Type 56 in Giant Condyloma Acuminatum.2014
- Author(s)
  Ishibuchi T, Shimizu A, Kato M, Takeuchi Y, Aoyama K, Yasuda M, Takahashi A, Okada E, Motegi SI, Amano H, Ishikawa O.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: 94 Issue: 4 Pages: 482-483
- DOI
  10.2340/00015555-1755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Human Papillomaviruses in Anogenital Epithelial Lesions.2014
- Author(s)
  Kato M, Shimizu A, Takeuchi Y, Hattori T, Abe M, Amano H, Motegi SI, Tamura A, Ishikawa O.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: 94 Issue: 5 Pages: 597-599
- DOI
  10.2340/00015555-1784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461683
[Journal Article] Detection of human papillomavirus type 58 in Periungual Bowen's disease.2013
- Author(s)
  Kato M, Shimizu A, Hattori T, Abe M, Amano H, Motegi S, Ishikawa O.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: 93 Issue: 6 Pages: 723-724
- DOI
  10.2340/00015555-1555
- Data Source
  KAKENHI-PROJECT-25461683
[Presentation] Human papillomavirus 58型を検出した爪部Bowen病の1例2023
- Author(s)
  落合咲和子, 山口礼門, 安澤数史, 大原國章, 清水晶
- Organizer
  第39回日本皮膚悪性腫瘍学会学術大会(名古屋）
- Data Source
  KAKENHI-PROJECT-22K08394
[Presentation] NAIL BOWEN DISEASE AND SQUAMOUS CELL CARCINOMA AS HIGH-RISK HPV-ASSOCIATED RESERVOIR SITES FOR SEXUALLY TRANSMITTED INFECTIONS.2023
- Author(s)
  Akira Shimizu, Reimon Yamaguchi, Kazushi Anzawa, Yuko Kuriyama, Kuniaki Ohara
- Organizer
  35th International papillomavirus conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08394
[Presentation] Novel polymerase chain reaction method for detecting cutaneous and beta genus human papillomavirus DNA2023
- Author(s)
  Reimon Yamaguchi, Mayumi Saito, Kazushi Anzawa, Akira Shimizu, Toshiyuki Sasagawa
- Organizer
  35th International papillomavirus conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08394
[Presentation] 皮膚筋炎病態形成に関与するウイルスとレトロトランスポゾンの探索2020
- Author(s)
  清水　晶、栗山裕子、金井早紀、石川　治　塚越博之（
- Organizer
  第119回日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-19K08766
[Presentation] HPV type 16陽性有棘細胞癌の1例－群馬大学皮膚科で経験した有棘細胞癌におけるHPV感染の検討－
- Author(s)
  清水　晶、加藤円香、竹内裕子、石川　治
- Organizer
  第112回日本皮膚科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25461683

1. TOMINAGA Hideyuki

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# of Collaborated Products: 1 results
2. KANAI Yoshikatsu

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# of Collaborated Products: 1 results
3. 坂倉浩一

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4. 佐野孝昭

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5. 奥山隆平

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6. 芦田敦子

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7. 徳永文稔

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# of Collaborated Products: 2 results
8. 織内昇

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Shimizu Akira 清水 晶

SHIMIZU Akira 清水 晶

清水 晶 シミズ アキラ

Research Projects

Research Products

Co-Researchers

粘膜型ハイリスクHPVによる爪部ボーエン病の発症機序と感染経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

粘膜悪性型HPV感染による爪部ボーエン病発症機序と新たなHPV感染経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elevated type I interferon expression in dermatomyositis: involvement of LINE-1 and viral infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Detection of human papillomaviruses in skin tumors and investigation of the pathgenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レトロウイルス以外のRNAウイルスもヒト細胞内で逆転写されるPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Visual Dermatology2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] The synchronized gene expression of retrotransposons and type I interferon in dermatomyositis.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of ER stress markers (GRP78/BiP and PERK) in adenoid cystic carcinoma.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acquired epidermodysplasia verruciformis associated with human papillomavirus type 47 in a HIV-infected patient2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct activation mechanisms of NF-κB regulator IKK by isoforms of the cell death regulator cFLIP.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic significance of thymidylate synthase (TS) expression in cutaneous malignant melanoma.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratotic condyloma acuminatum.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generalized keratosis pilaris-like eruptions in a chronic myelogenous leukemia patient treated with nilotinib.2016

Author(s)

Journal Title

DOI

Shimizu Akira 清水晶

SHIMIZU Akira 清水晶

清水晶シミズアキラ