KAWAKUBO MASATOMO 川久保雅友

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KAWAKUBO Masatomo 川久保雅友

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Researcher Number	70397305
Other IDs	https://orcid.org/0000-0001-5106-5742
Affiliation (Current)	2025: 信州大学, 学術研究院医学系, 講師
Affiliation (based on the past Project Information) *help	2018 – 2021: 信州大学, 学術研究院医学系, 講師 2014 – 2017: 信州大学, 学術研究院医学系, 助教 2013: 信州大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Experimental pathology Except Principal Investigator Experimental pathology
Keywords	Principal Investigator αGlcNAc / C57Bl/6マウス / GH89 family / 腸内細菌 / ムチン要求性 / マウス / 腸内細菌叢 / 糖鎖 / 胃腺粘液 / 胃粘膜糖鎖 … More / モデルマウス / 胃癌発生機序 / 胃癌発生 / 好中球 / 胃粘液 / ピロリ菌感染 / エピジェネティック / ピロリ菌 / 胃癌 / A4gnt欠損マウス … More Except Principal Investigator ノックアウトマウス / 癌 / IL-33シグナル / 遺伝子改変マウス / ゲノム編集 / ダブルノックアウトマウス / サイトカイン / 炎症 / 糖鎖 / 胃癌 Less

Feedbak mechanism for host by microflora degradation of gastro-duodena gland mucinPrincipal Investigator
- Principal Investigator
  
  Kawakubo Masatomo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shinshu University
Progression of the gastric cancer using novel mouse spontaneously developed differentiated type adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  Kawakubo Masatomo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shinshu University
Role of IL-33 on gastric cancer development -Analysis using new model mice-
- Principal Investigator
  
  NAKAYAMA Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Shinshu University

All 2021 2019 2018 2017 2016 2014

All Journal Article Presentation Patent

[Journal Article] Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL2021
- Author(s)
  Kobayashi Junichi、Kawakubo Masatomo、Fujii Chifumi、Arisaka Nobuhiko、Miyashita Masaki、Sato Yoshiko、Komura Hitomi、Matoba Hisanori、Nakayama Jun
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 16
- DOI
  10.1073/pnas.2016469118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08419, KAKENHI-PROJECT-19H03441
[Journal Article] Analysis of A4gnt Knockout Mice Reveals an Essential Role for Gastric Sulfomucins in Preventing Gastritis Cystica Profunda2019
- Author(s)
  Masatomo Kawakubo, Hitomi Komura, Yukinobu Goso, Motohiro Okumura, Yoshiko Sato, Chifumi Fujii, Masaki Miyashita, Nobuhiko Arisaka, Satoru Harumiya, Kazuhiro Yamanoi, Shigenori Yamada, Shigeru Kakuta, Hiroto Kawashima, Michiko N Fukuda, Minoru Fukuda, Jun Nakayama
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 67 Issue: 10 Pages: 759-770
- DOI
  10.1369/0022155419860134
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08419, KAKENHI-PROJECT-17K17779, KAKENHI-PROJECT-19K16555, KAKENHI-PROJECT-17K19542
[Journal Article] Cholesterol-α-glucosyltransferase gene is present in most Helicobacter species including gastric non-Helicobacter pylori helicobacters obtained from Japanese patients.2018
- Author(s)
  Kawakubo M, Horiuchi K, Matsumoto T, Nakayama J, Akamatsu T, Katsuyama T, Ota H, Sagara J
- Journal Title
  
  Helicobacter
  
  Volume: 23 Issue: 1
- DOI
  10.1111/hel.12449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08708
[Journal Article] Cloning of Helicobacter suis cholesterol α-glucosyltransferase and production of an antibody capable of detecting it in formalin-fixed, paraffin-embedded gastric tissue sections,2017
- Author(s)
  Masatomo Kawakubo, Kazuki Horiuchi, Hitomi Komura, Yoshiko Sato, Masayoshi Kato, Meguru Ikeyama, Mana Fukushima, Shigenori Yamada, Satoshi Ishizone, Takehisa Matsumoto, Hiroyoshi Ota, Junji Sagara, Jun Nakayama
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 印刷中 Issue: 4 Pages: 463-471
- DOI
  10.1007/s00418-017-1582-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08708, KAKENHI-PROJECT-17K17779, KAKENHI-PROJECT-15H04712
[Journal Article] Helicobacter heilmannii sensu stricto-related gastric ulcers: a case report2014
- Author(s)
  Matsumoto T, Kawakubo M, Akamatsu T, Koide N, Ogiwara N, Kubota S, Sugano M, Kawakami Y, Katsuyama T, Ota H
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 20 Issue: 12 Pages: 3376-3382
- DOI
  10.3748/wjg.v20.i12.3376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670191
[Journal Article] Development of a PCR method for the detection of Helicobacter suis in gastric biopsy specimens.2014
- Author(s)
  Matsui H, Takahashi T, Yamagata-Murayama S, Uchiyama I, Yamaguchi K, Shigenobu S, Matsumoto T, Kawakubo M, Ota H, Osaki T, Kamiya S, Takahashi S, Nakamura S, Nakamura M
- Journal Title
  
  Helicobacter
  
  Volume: in press Issue: 4 Pages: 260-271
- DOI
  10.1111/hel.12127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590518, KAKENHI-PROJECT-25670191, KAKENHI-PROJECT-25860099, KAKENHI-PLANNED-22128008
[Patent] 抗ピロリ菌活性を有するコレステロール類似物質2021
- Inventor(s)
  中山淳，川久保雅友
- Industrial Property Rights Holder
  国立大学法人信州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K08419
[Presentation] Gastritis Cystica Profunda の発生抑制における胃スルホムチンの役割の解明2019
- Author(s)
  川久保雅友，小村仁美，五艘行信，奥村征大，佐藤佳子，藤井千文，宮下聖基，有坂宣彦，春宮覚，山ノ井一裕，山田重徳，角田茂，川島博人，福田道子，福田穣，中山淳
- Organizer
  第60 回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08419
[Presentation] ホルマリン固定パラフィン包埋切片を用いた免疫染色に有用なハイルマーニ菌特異抗体の樹立2016
- Author(s)
  川久保雅友，佐藤佳子，小村仁美，池山環，福島万奈，太田浩良，相良淳二，中山淳
- Organizer
  第57回日本組織細胞化学会学術集会
- Place of Presentation
  東京都, 三鷹市，杏林大学井の頭キャンパス
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-16K08708

1. NAKAYAMA Jun (10221459)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. KAKUTA Shigeru (80345032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKAMOTO Masaya (90226928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Arisaka Nobuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Miyashita Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大さき敬子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 神谷茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高橋信一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAKUBO MASATOMO 川久保 雅友

KAWAKUBO Masatomo 川久保 雅友

Research Projects

Research Products

Co-Researchers

Feedbak mechanism for host by microflora degradation of gastro-duodena gland mucinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Progression of the gastric cancer using novel mouse spontaneously developed differentiated type adenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of IL-33 on gastric cancer development -Analysis using new model mice-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of A4gnt Knockout Mice Reveals an Essential Role for Gastric Sulfomucins in Preventing Gastritis Cystica Profunda2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cholesterol-α-glucosyltransferase gene is present in most Helicobacter species including gastric non-Helicobacter pylori helicobacters obtained from Japanese patients.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cloning of Helicobacter suis cholesterol α-glucosyltransferase and production of an antibody capable of detecting it in formalin-fixed, paraffin-embedded gastric tissue sections,2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Helicobacter heilmannii sensu stricto-related gastric ulcers: a case report2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a PCR method for the detection of Helicobacter suis in gastric biopsy specimens.2014

Author(s)

Journal Title

DOI

Data Source

[Patent] 抗ピロリ菌活性を有するコレステロール類似物質2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Gastritis Cystica Profunda の発生抑制における胃スルホムチンの役割の解明2019

Author(s)

Organizer

Data Source

[Presentation] ホルマリン固定パラフィン包埋切片を用いた免疫染色に有用なハイルマーニ菌特異抗体の樹立2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KAWAKUBO MASATOMO 川久保雅友

KAWAKUBO Masatomo 川久保雅友