MINOHARA Motozumi 三野原元澄

Researcher Number	70398113
Affiliation (based on the past Project Information) *help	2009 – 2011: Kyushu University, 大学病院, 特任講師 2008: Kyushu University, 大学病院, 講師 2007 – 2008: Kyushu University, 大学病院, 助教 2006: Kyushu University, Department of Neurology, Research Fellow for Collaborative, 大学院医学研究院, 共同研究員 2005: 九州大学, 大学院・医学研究院, 共同研究員
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator Neurology
Keywords	Principal Investigator 多発性硬化症 / NMO / MRI / LESCL / EAE / 実験的自己免疫性脳脊髄炎 / Brazil / China / HLA-class II / optico-spinal MS … More / multiple sclerosis / HLA / 視神経脊髄型 / ブラジル / 中国 / HLAクラスII / 視神経脊髄型MS / CJDND1 / タイトジャンクション / 血液脳関門 / ミエリン / CLDND1 / claudin / Rho / 自己反応性T細胞 / fasudil / 低分子量GTPase / Rho-kinase … More Except Principal Investigator 多発性硬化症 / IL-17 / IL7RA / バイオマーカー / 自己抗体プロファイル / IL2RA / HLA / 視神経脊髄炎 / 自己抗体 / サイトカイン / 遺伝子間相互作用 / Caspr / ギラン・バレー症候群 / Naチャンネル / 軸索傷害 / Dps / Campylobacter jejuni / ギランバレー症候群 / 好中球 / 再発惹起因子 / 自然免疫 / ELISPOT / 抗AQP4抗体 / 自己反応性T細胞 / 視神経脊髄型 Less

Development of molecular targeted therapy of multiple sclerosis on the basis of membrane protein microarray analysis and gene interactions
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Analysis of autoimmune response to claudin-family proteins in demyelinating disease.Principal Investigator
- Principal Investigator
  
  MINOHARA Motozumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
軸索型ギラン・バレー症候群先行感染菌由来蛋白の軸索膜ポア形成による傷害とその治療
- Principal Investigator
  
  吉良潤一
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
natural immunity dysregulation and relapse inducing factor in patient with opticospinal multiple sclerosis
- Principal Investigator
  
  KAWANO Yuji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Ehime University
  Kyushu University
Rho-kinase inhibitor : a novel therapeutic approach for multiple sclerosisPrincipal Investigator
- Principal Investigator
  
  MINOHARA Motozumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Role of IL-17 producing T cells in opticospinal multiple sclerosis
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
HLA class II polymorphism and worldwide susceptibility to optico-spinal multiple sclerosis.Principal Investigator
- Principal Investigator
  
  MINOHARA Motozumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYUSHU UNIVERSITY

All 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 多発性硬化症の診断と治療2008
- Author(s)
  三野原元澄, 吉良潤一
- Total Pages
  285
- Publisher
  新興医学出版
- Data Source
  KAKENHI-PROJECT-19590996
[Book] 神経疾患最新の治療2006-2008、多発性硬化症2006
- Author(s)
  三野原元澄他
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-18390261
[Book] 神経疾患最新の治療2006-2008、多発性硬化症2006
- Author(s)
  三野原元澄他
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590881
[Book] 神経疾患最新の治療 2006-20082006
- Author(s)
  三野原元澄他
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-17590881
[Book] 多発性硬化症神経疾患最新の治療2006-2008(小林祥泰、水澤英洋(編))2006
- Author(s)
  三野原元澄、吉良潤一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Selective impairment of optic flow perception in amnestic mild cognitive impairment : evidence from event-related potentials2012
- Author(s)
  Yamasaki T, Goto Y, Ohyagi Y, Monji A, Munetsuna S, Minohara M, Minohara K, Kira J, Kanba S, Tobimatsu S
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 28 Pages: 695-708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Alterd production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis2012
- Author(s)
  Yoshimura S, Ochi H, Isobe N, Matsushita T, Motomura K, Matsuoka T, Minohara M, Kira J
- Journal Title
  
  Mult Scler
  
  Volume: 16 Pages: 1178-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] T cell reactivities to myelin protein-derived peptides in neuromyelitis optica patients with anti-aquaporin-4 antibody2011
- Author(s)
  Yonekawa T, Matsushita T, Minohara M, Isobe N, Masaki K, Yoshimura S, Nishimura S, Kira J
- Journal Title
  
  Neurology Asia
  
  Volume: 16 Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390178
[Journal Article] Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis2011
- Author(s)
  Pineda AA, Minohara M, Kawamura N, Matsushita T, Yamasaki R, Sun X, Piao H, Shimokawa H, Kira J
- Journal Title
  
  J Neurol Sci
  
  Volume: 309 Pages: 115-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Tissue binding patterns and in vitro effects of Campylobacter jejuni DNA-binding protein from starved cells2011
- Author(s)
  Piao H, Minohara M, Kawamura N, Li W, Matsushita T, Yamasaki R, Mizunoe Y, Kira J
- Journal Title
  
  Neurochem Res
  
  Volume: 36 Pages: 58-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Campylobacter jejuni DNA-binding protein from starved cells in Guillain-Barre syndrome patients2011
- Author(s)
  Kawamura N, Piao H, Minohara M, Matsushita T, Kusunoki S, Matsumoto H, Ikenaka K, Miunoe Y, Kira J
- Journal Title
  
  J Neuroimmunol
  
  Volume: 240-241 Pages: 74-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Induction of paranodal myelin detachment and sodium channel loss in vivo by Campylobacter jejuni DNAbinding protein from starved cells(C-DPS) in myelinated nerve fibers2010
- Author(s)
  Piao H, Minohara M, Kawamura N, Li W, Mizunoe Y, Umehara F, Goto Y, Kusunoki S, Matsushita T, Ikenaka K, Maejima T, Nabekura J, Yamasaki R, Kira J
- Journal Title
  
  J Neurol Sci
  
  Volume: 288 Pages: 54-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Altered production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis2010
- Author(s)
  Yoshimura S, Ochi H, Isobe N, Matsushita T, Motomura K, Matsuoka T, Minohara M, Kira J
- Journal Title
  
  Mult Scler
  
  Volume: 16 Issue: 10 Pages: 1178-1188
- DOI
  10.1177/1352458510375706
- NAID
  120005227139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390178
[Journal Article] Association of the HLADPB1^*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders2009
- Author(s)
  Matsushita T, Matsuoka T, Isobe N, Kawamura Y, Minohara M, Shi N, Nishimura Y, Ochi H, Kira J
- Journal Title
  
  Tissue Antigens 72
  
  Pages: 171-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590996
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J
- Journal Title
  
  Multiple Sclerosis 15
  
  Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590996
[Journal Article] Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis2009
- Author(s)
  Matsuoka T, Matsushita T, Osoegawa M, Kawano Y, Minohara M, Mihara F, Nishimura Y, Ohyagi Y, Kira J
- Journal Title
  
  Multiple Sclerosis 14
  
  Pages: 1181-1190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J
- Journal Title
  
  Multiple Sclerosis 15
  
  Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Association of the HLA-DPB1* 0501 allele with antiaquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders2009
- Author(s)
  Matsushita T, Matsuoka T, Isobe N, Kawano Y, Minohara M, Shi N, Nishimura Y, Ochi H, Kira J
- Journal Title
  
  Tissue Antigens
  
  Volume: 73 Pages: 173-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica2009
- Author(s)
  Li W, Minohara M, Piao H, Matsushita T, Masaki K, Matsuoka T, Isobe N, Su JJ, Ohyagi Y, Kira J
- Journal Title
  
  Mult Scler
  
  Volume: 15 Pages: 1411-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Association of the HLADPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders2009
- Author(s)
  Matsushita T, Matsuoka T, Isobe N, Kawamura Y, Minohara M, Shi N, Nishimura Y, Ochi H, Kira J
- Journal Title
  
  Tissue Antigens 72
  
  Pages: 171-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Helicobacter pylori is a potential protective factor against conventional type multiple sclerosis in the Japanese population2009
- Author(s)
  Li W, Minohara M, Su JJ, Matsuoka T, Osoegawa M, Ishizu T, Kira J
- Journal Title
  
  J Neuroimmunol 184
  
  Pages: 227-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590996
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, ochi H, Kira J
- Journal Title
  
  Mult Scler
  
  Volume: 15 Pages: 304-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591090
[Journal Article] Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis2008
- Author(s)
  Matsuoka T, Matsushita T, Osoegawa M, Kawano Y, Minohara M, Mihara F, Nishimura Y, Ohyagi Y, Kira J
- Journal Title
  
  Multiple Sclerosis 14
  
  Pages: 1181-1190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590996
[Journal Article] Distinct CSF cytokine/chemokine profiles in atopic myelitis and other causes of myelitis2008
- Author(s)
  Tanaka M, Matsushita T, Tateishi T, Ochi H, Kawano Y, Mei F-J, Minohara M, Murai H, Kira J
- Journal Title
  
  Neurology 71
  
  Pages: 974-981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590996
[Journal Article] Distinct CSF cytokine/chemokine profiles in atopic myelitis and other causes of myelitis2008
- Author(s)
  Tanaka M, Matsushita T, Tateishi T, Ochi H, Kawano Y, Mei F-J, Minohara M, Murai H, Kira J
- Journal Title
  
  Neurology 71
  
  Pages: 974-981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Helicobacter pylori is a potential protective factor against conventional type multiple sclerosis in the Japanese population2007
- Author(s)
  Li W, Minohara M, Su JJ, Matsuoka T, Osoegawa M, Ishizu T, Kira J
- Journal Title
  
  J Neuroimmunol 184
  
  Pages: 227-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese2007
- Author(s)
  Matsuoka T, Matsushita T, Kawano Y, Osoegawa M, Ochi H, Ishizu T, Minohara M, Kikuchi H, Mihara F, Ohyagi Y, Kira J
- Journal Title
  
  Brain 130
  
  Pages: 1206-1223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese2007
- Author(s)
  Matsuoka T, Matsushita T, Kawano Y, Osoegawa M, Ochi H, Ishizu T, Minohara M, Kikuchi H, Mihara F, Ohyagi Y, Kira J
- Journal Title
  
  Brain 130
  
  Pages: 1206-1223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590996
[Journal Article] Upregulation of myeloperoxidase in patients with opticospinal multiple sclerosis : positive correlation with disease severity2006
- Author(s)
  Minohara M, Matsuoka T, Li W, Osoegawa M, Ishizu T, Ohyagi Y, Kira J
- Journal Title
  
  J Neuroimmunol 178
  
  Pages: 156-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Upregulation of myeloperoxidase in patients with opticospinal multiple sclerosis : positive conelation with disease severity.2006
- Author(s)
  Minohara M et al.
- Journal Title
  
  J Neuroimmunol 178
  
  Pages: 156-160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590881
[Journal Article] Upregulation of myeloperoxidase in patients with opticospinal multiple sclerosis : positive correlation with disease severity.2006
- Author(s)
  Minohara M et al.
- Journal Title
  
  J Neuroimmunol 178
  
  Pages: 156-160
- Data Source
  KAKENHI-PROJECT-17590881
[Journal Article] Upregulation of myeloperoxidase in patients with opticospinal multiple sclerosis : positive correlation with disease severity.2006
- Author(s)
  Minohara M et al.
- Journal Title
  
  J Neuroimmunol 178
  
  Pages: 156-160
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Upregulation of vascular growth factors in multiple sclerosis : correlation with MRI findings2006
- Author(s)
  Su J-J, Osoegawa M, Minohara M, Tanaka M, Ishizu T, Mihara F, Taniwaki T, Kira J
- Journal Title
  
  J Neurol Sci 243
  
  Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] Upregulation of myeloperoxidase in patients with opticospinal multiple sclerosis : positive correlation with disease severity.2006
- Author(s)
  Minohara M et al.
- Journal Title
  
  J Neuroimmunol 178 (1-2)
  
  Pages: 156-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590881
[Journal Article] Long-term favorable response to interferon beta-1b is linked to cytokine deviation toward the Th2 and Tc2 sides in Japanese patients with multiple sclerosis2006
- Author(s)
  Mei F-J, Osoegawa M, Ochi H, Minohara M, Shi N, Murai H, Ishizu T, Taniwaki T, Kira J
- Journal Title
  
  J Neurol Sci 246
  
  Pages: 71-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Journal Article] The selective Rho-kinase inhibitor Fasudil is protective and therapeutic in experimental allergic encephalomyelitis2006
- Author(s)
  Sun X, Minohara M, Kikuchi S, Ishizu T, Tanaka M, Piao H, Osoegawa M, Ohyagi Y, Shimokawa H, Kira J
- Journal Title
  
  J Neuroimmunol 180
  
  Pages: 126-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] C. jejuni感染後ギランバレー症候群におけるC-Dpsおよび抗体反応の検出2010
- Author(s)
  河村信利、朴華、三野原元澄、楠進、水之江義充、吉良潤一
- Organizer
  第22回日本神経免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] C. jejuni感染後ギラン・バレー症候群における抗C-Dps抗体およびC-Dpsの検出2010
- Author(s)
  河村信利、朴華、三野原元澄、楠進、水之江義充、吉良潤一
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] 脱髄疾患におけるCLDND1の病理学的検討2010
- Author(s)
  真崎勝久、三野原元澄、米川智、磯部紀子、松下拓也、吉良潤一
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] 中枢神経系におけるCLDND1の発現と脱髄疾患への関与2010
- Author(s)
  真崎勝久、三野原元澄、米川智、磯部紀子、松下拓也、吉良潤一
- Organizer
  第22回日本神経免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] 末梢免疫担当細胞におけるbrain-derived neurotrophicfactor (BDNF)産生能と多発性硬化症(MS)病態との関連2009
- Author(s)
  吉村怜、越智博文、三野原元澄、吉良潤一
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗aquaporin-4(AQP4)抗体陽性例におけるT細胞内サイトカイン, 脳脊髄液柱サイトカインの動向2009
- Author(s)
  松下拓也, 磯部紀子, 松岡健, 三野原元澄, 河野祐治, 吉良潤一
- Organizer
  第21回神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590994
[Presentation] ヘリコバクターピロリ感染による多発性硬化症の重症化2009
- Author(s)
  三野原元澄, ら
- Organizer
  日本神経学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] 多発性硬化症におけるヘリコバクターピロリ感染の影響2009
- Author(s)
  三野原元澄、李巍、松下拓也、松岡健、磯部紀子、吉良潤一
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] 抗aquaporin-4 (AQP4)抗体陽性例におけるT臍オブ内サイトカイン, 脳脊髄液柱サイトカインの動向2009
- Author(s)
  松下拓也, 磯部紀子, 松岡健, 三野原元澄, 河野祐治, 吉良潤一
- Organizer
  第21回神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590994
[Presentation] ヘリコバクターピロリ感染による多発性硬化症の重症化2009
- Author(s)
  三野原元澄, ら
- Organizer
  日本神経学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] FACS を用いた高感度抗AQP4抗体の検出 : サブクラス解析を含めて2009
- Author(s)
  磯部紀子、河野祐治、松下拓也、松岡健、河村信利、三野原元澄、吉良潤一
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] ヘリコバクターピロリ感染による多発性硬化症の重症化2009
- Author(s)
  三野原元澄、李巍、松下拓也、松岡健、磯部紀子、石津尚明、吉良潤一
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591090
[Presentation] 多発性硬化症におけるヘリコバクターピロリ感染の影響2009
- Author(s)
  三野原元澄、李巍、松下拓也、松岡健、磯部紀子、吉良潤一
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 多発性硬化症におけるヘリコバクターピロリ感染の影響2009
- Author(s)
  三野原元澄ら
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] FACSを用いた高感度抗AQP4抗体検出法の開発2008
- Author(s)
  河野祐治、松下拓也、松岡健、史楠、河村信利、三野原元澄、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗CLDND1抗体陽性多発性硬化症の臨床像2008
- Author(s)
  三野原元澄ら
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 多発性硬化症におけるヘリコバクターピロリ感染の影響2008
- Author(s)
  三野原元澄ら
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-03-13
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] 抗CLDND1抗体陽性多発性硬化症の臨床像2008
- Author(s)
  三野原元澄ら
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] MS 髄液におけるCD4^+TNFα^+IL2^-T細胞サブセット異常2008
- Author(s)
  史楠、河野祐治、梅風君、松岡健、三野原元澄、越智博文、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗CLDND1抗体陽性多発性硬化症を抗AQP4抗体との関連2008
- Author(s)
  三野原元澄ら
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗体価と臨床像からみた抗aquaporin-4(AQP4)抗体の意義2008
- Author(s)
  松岡健、松下拓也、河野祐治、三野原元澄、吉良潤一
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] Hypercomplementemia at Relapse in Patients with Anti-Aquaporin-4 Antibody2008
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka M, Minohara M, Ochi H, Kira J.
- Organizer
  PACTRIMS for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  Kuala Lumpur
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] FACSによる抗native AQP4抗体の高感度検出法の開発2008
- Author(s)
  河野祐治、松下拓也、松岡健、河村信利、三野原元澄、吉良潤一
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗CLDND1抗体陽性多発性硬化症と抗AQP4抗体との関連2008
- Author(s)
  三野原元澄、松下拓也、松岡健、河村信利、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] Distinct cerebrospinal fluid cytokine/chemokine profiles in opticospinal multiple sclerosis,atopic myelitis and other causes of myelitis2008
- Author(s)
  Kira J, Tanaka M, Matsushita T, Matuoka T, Tateishi T, Minohara M.
- Organizer
  WORLD CONGRESS ON TREATMENT AND RESEARCH IN MULTIPLE SCLEROSIS
- Place of Presentation
  Montreal, Canada
- Year and Date
  2008-09-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗CLDND1抗体陽性多発性硬化症を抗AQP4抗体との関連2008
- Author(s)
  三野原元澄ら
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] 抗CLDND1抗体陽性多発性硬化症を抗AQP4抗体との関連2008
- Author(s)
  三野原元澄ら
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] 抗aquaporin-4(AQP4)抗体価による多発性硬化症の免疫学的・遺伝学的背景の差異2008
- Author(s)
  河野祐治、松下拓也、松岡健、史楠、三野原元澄、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 多発性硬化症におけるconformational にAQP1を認識する抗体の検索2008
- Author(s)
  河村信利、松下拓也、三野原元澄、河野祐治、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗AQP4抗体価からみた日本人多発性硬化症患者の病像・画像所見の特徴 : 抗AQP4抗体の役割について2008
- Author(s)
  松岡健、松下拓也、河野祐治、三野原元澄、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 抗CLDND1抗体陽性多発性硬化症の臨床像2008
- Author(s)
  三野原元澄ら
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] 日本人多発性硬化症におけるMRI所見とHLAクラスII遺伝子多型との相関2007
- Author(s)
  三野原元澄、松岡健、松下拓也、小副川学、越智博文、吉良潤一
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 日本人多発性硬化症におけるMRI所見とHLAクラスII遺伝子多型との相関2007
- Author(s)
  三野原元澄他
- Organizer
  日本神経学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 日本人多発性硬化症における抗CLDND1抗体の意義2007
- Author(s)
  三野原元澄他
- Organizer
  日本神経免疫学会
- Place of Presentation
  金沢
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 日本人多発性硬化症における抗aquaporin-4抗体陽性率と陽性例と陰性例との臨床像の比較2007
- Author(s)
  松下拓也、河野祐治、松岡健、小副川学、三野原元澄、吉良潤一
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 日本人多発性硬化症における抗CLDND1抗体の意義2007
- Author(s)
  三野原元澄、松下拓也、松岡健、小副川学、村井弘之、吉良潤一
- Organizer
  第19回日本神経免疫学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 日本人多発性硬化症における抗CLDND1抗体の意義2007
- Author(s)
  三野原元澄, 他
- Organizer
  日本神経免疫学会
- Place of Presentation
  金沢
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] 日本人多発性硬化症におけるMRI所見とHLAクラスII遺伝子多型との相関2007
- Author(s)
  三野原元澄, ら
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] 臨床型と抗aquaporin-4(AQP4)抗体からみた日本人多発性硬化症の長大な脊髄病巣の解析2007
- Author(s)
  松岡健、松下拓也、河野祐治、小副川学、三野原元澄、吉良潤一
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 実験的自己免疫性神経炎にたいするRhi-kinase阻害剤の効果2007
- Author(s)
  三野原元澄, 他
- Organizer
  日本末梢神経学会
- Place of Presentation
  弘前
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] Serum autoantibodies to claudin domain containing 1 protein in Japanese patients with multiple sclerosis.2007
- Author(s)
  Minohara M, et. al.
- Organizer
  ECTRIMS
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] 日本人多発性硬化症におけるMRI所見とHLAクラスII遺伝子多型との相関2007
- Author(s)
  三野原元澄, 他
- Organizer
  日本神経学会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-18390261
[Presentation] Serum autoantibodies to claudin domain containing 1 protein in Japanese patients with multiple sclerosis2007
- Author(s)
  Minohara M, Matsuoka T, Matsushita T, Kawamura N, Kira J
- Organizer
  Congress of the European Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 自験多発性硬化症患者の画像所見とHLAとの関連 : 連続121例の解析結果2007
- Author(s)
  松岡健、三野原元澄、松下拓也、小副川学、越智博文、吉良潤一
- Organizer
  第19回日本神経免疫学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PROJECT-19590996
[Presentation] 日本人多発性硬化症における血清myeloperoxidase値の上昇2006
- Author(s)
  三野原元澄, ら
- Organizer
  第18回日本神経免疫学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2006-03-02
- Data Source
  KAKENHI-PROJECT-18390261

1. KAWAMURA Nobutoshi (00432930)

# of Collaborated Projects: 5 results

# of Collaborated Products: 14 results
2. KIRA Jun-ichi (40183305)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
3. KAWANO Yuji (20333479)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
4. MATSUSHITA Takuya (00533001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. 土井光 (30423552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YOSHIMURA Satoshi (20596390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. MURAI Hiroyuki (80325464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OSOEGAWA Manabu (60380614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 菊池仁志 (60322765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MINOHARA Motozumi 三野原 元澄

Research Projects

Research Products

Co-Researchers

Development of molecular targeted therapy of multiple sclerosis on the basis of membrane protein microarray analysis and gene interactions

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Analysis of autoimmune response to claudin-family proteins in demyelinating disease.Principal Investigator

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軸索型ギラン・バレー症候群先行感染菌由来蛋白の軸索膜ポア形成による傷害とその治療

Principal Investigator

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natural immunity dysregulation and relapse inducing factor in patient with opticospinal multiple sclerosis

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Rho-kinase inhibitor : a novel therapeutic approach for multiple sclerosisPrincipal Investigator

Principal Investigator

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Role of IL-17 producing T cells in opticospinal multiple sclerosis

Principal Investigator

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HLA class II polymorphism and worldwide susceptibility to optico-spinal multiple sclerosis.Principal Investigator

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[Book] 多発性硬化症の診断と治療2008

Author(s)

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[Book] 神経疾患最新の治療2006-2008、多発性硬化症2006

Author(s)

Publisher

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[Book] 神経疾患最新の治療2006-2008、多発性硬化症2006

Author(s)

Publisher

Description

Data Source

[Book] 神経疾患 最新の治療 2006-20082006

Author(s)

Publisher

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[Book] 多発性硬化症神経疾患最新の治療2006-2008(小林祥泰、水澤英洋(編))2006

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[Journal Article] Selective impairment of optic flow perception in amnestic mild cognitive impairment : evidence from event-related potentials2012

Author(s)

Journal Title

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[Journal Article] Alterd production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis2012

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[Journal Article] T cell reactivities to myelin protein-derived peptides in neuromyelitis optica patients with anti-aquaporin-4 antibody2011

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MINOHARA Motozumi 三野原元澄

[Book] 神経疾患最新の治療 2006-20082006