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HIROTA Morihisa  廣田 衛久

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… Alternative Names

廣田 衛久  ヒロタ モリヒサ

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Researcher Number 70400364
Affiliation (Current) 2025: 東北医科薬科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2023: 東北医科薬科大学, 医学部, 教授
2015: 東北大学, 大学病院, 助教
2007 – 2011: 東北大学, 病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Gastroenterology
Except Principal Investigator
Radiation science / Gastroenterology
Keywords
Principal Investigator
膵癌 / 骨髄由来幹細包 / グリーンマウス / 慢性膵炎 / 骨髄由来細胞 / 膵臓学 / 胆道学
Except Principal Investigator
ALS / 定量解析 / 膵血流 … More / ASL / 3TMRI / 血流 / 膵機能 / ASL法 / MRI / 骨髄由来細胞 / 幹細胞 / 膵癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (7 People)
  •  一般検診の基本的データを用いた人工知能による膵癌マススクリーニング法の確立Principal Investigator

    • Principal Investigator
      廣田 衛久
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku Medical and Pharmaceutical University
  •  Perfusion imaging of the pancreas using an arterial spin labeling technique on 3.0T MRI; initial experience

    • Principal Investigator
      Masashi Tsuda
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Bone marrow derived cells in the experimental mouse pancreatic cancer.Principal Investigator

    • Principal Investigator
      HIROTA Morihisa
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Development of pancreatic cancer stem cell targeted therapy using cells derived from bone marrow

    • Principal Investigator
      SATOH Kennichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University

All 2023 2012 2011 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG22012

    • Author(s)
      濱田晋, 佐藤賢一, 廣田衛久, 他
    • Journal Title

      Journal of Cellular Physiology

      Volume: 227巻 Pages: 729-738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590871
  • [Journal Article] The homepbox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of the transporter gene ABCG22011

    • Author(s)
      濱田晋、佐藤賢一、廣田衛久, 他
    • Journal Title

      Journal of Cellular Physiology

      Volume: 227 Pages: 729-738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590871
  • [Journal Article] Perfusion computed tomography findings of autoimmune pancreas2011

    • Author(s)
      廣田衛久, 他
    • Journal Title

      Pancreas

      Volume: 49巻 Pages: 1295-1301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590871
  • [Journal Article] Expression of the calcium-binding protein S100P is regulated by bone morphogenetic protein in pancreatic duct epithelial cell lines2009

    • Author(s)
      Hamada S, Satoh K, Hirota M, Fujibuchi W, Kanno A, Umino J, Ito FI, Satoh A, Kikuta K, Kume K, Masamune A, Shimosegawa T
    • Journal Title

      Cancer Sci 100

      Pages: 103-110

    • NAID

      10025141512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Expression of the calcium-binding protein S100P is regulated by bone morphogenetic protein in pancreatic duct epithelial cell lines2009

    • Author(s)
      Hamada, S, Satoh K ; Hirota M, Fujibuchi W, Kanno A ; Umino J ; Ito H ; Satoh A ; Kikuta K ; Kume, K ; Masamune A, Shimosegawa T
    • Journal Title

      Cancer Sci 100

      Pages: 103-10

    • NAID

      10025141512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Expression of Sonic hedgehog signaling pathway correlates with the tumorigenesis of intraductal papillary mucinous neoplasm of the pancreas2008

    • Author(s)
      Satoh K, Kanno A, Hamada S, Hirota M, Umino J, Masamune A, Egawa S, Motoi F, Unno M, Shimosegawa T
    • Journal Title

      Oncol Rep 19

      Pages: 1185-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Up-Regulation of MSX2 Enhances the Malignant Phenotype and is Associated with Twist 1 Expression in Human Pancreatic Cancer Cells2008

    • Author(s)
      Satoh K, Hamada S, Kimura K, Kanno A, Hirota M, Umino J, Fujibuchi W, MasamuneA, Tanaka N, Miura K, Egawa S, Motoi F, Unno M, Vonderhaar BK, Shimosegawa T
    • Journal Title

      Am J Pathol 172

      Pages: 926-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Unno, M, Shimosegawa T. Periostin, secreted from stromal cells, has biphasic effect on cell migration and correlates with the epithelial to mesenchymal transition of human pancreatic cancer cells2008

    • Author(s)
      Kanno A, Satoh K, Masamune A, Hirota M, Kimura K, Umino J, Hamada S, Satoh A, Egawa S, Motoi F
    • Journal Title

      Int J Cancer 122

      Pages: 2707-2718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Up-Regulation of MSX2 Enhances the Malignant Phenotype and Is Associated with Twist 1 Expression in Human Pancreatic Cancer Cells.2008

    • Author(s)
      Satoh K, Hamada S, Kimura K, Kanno A, Hirota M, Umino J, Fujibuchi W, MasamuneA, Tanaka N, Miura K, Egawa S, Motoi F, Unno M, Vonderhaar BK, Shimosegawa T.
    • Journal Title

      Am J Pathol 172

      Pages: 926-939

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Periostin, secreted from stromal cells, has biphasic effect on cell migration and correlates with the epithelial to mesenchymal transition of human pancreatic cancer cells2008

    • Author(s)
      Kanno A, Satoh K, Masamune A, Hirota M, Kimura K, Umino J, Hamada S, Satoh A, Egawa S, Motoi F, Unno M, Shimosegawa T
    • Journal Title

      Int J Cancer 122

      Pages: 2707-2718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Bone morphogenetic protein 4 induces epithelial-mesenchymal transition throughMSX2 induction on pancreatic cancer cell line.2007

    • Author(s)
      Hamada S, Satoh K, Hirota M, Kimura K, Kanno A, Masamune A, Shimosegawa T.
    • Journal Title

      J Cell Physiol 213

      Pages: 768-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Activation of Notch signaling in tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracene in mice.2007

    • Author(s)
      Kimura K, Satoh K, Kaimo A, Hamada S, Hirota M, Endoh M, Masamune A, Shimosegawa T
    • Journal Title

      Cancer Sci 98

      Pages: 155-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Activation of Notch signaling in tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracene in mice2007

    • Author(s)
      Kimura K, Satoh K, Kanno A, Hamada S, Hirota M, Endoh M, Masamune A, Shimosegawa T
    • Journal Title

      Cancer Sci 98

      Pages: 155-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Journal Article] Bone morphogenetic protein 4 induces epithelial-mesenchymal transition through MSX2 induction on pancreatic cancer cell line2007

    • Author(s)
      Hamada S, Satoh K, Hirota M, Kimura K, Kanno A, Masamune A, Shimosegawa T
    • Journal Title

      J Cell Physiol 213

      Pages: 768-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Presentation] 一般検査項目を用いた人工知能(AI)による膵癌スクリーニング法の検討2023

    • Author(s)
      小岩井明信、廣田衛久、高須充子、佐藤賢一
    • Organizer
      第54回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-23K07401
  • [Presentation] 膵癌細胞株におけるBMP4によるカルシウム結合蛋白S100Pの発現誘導とその機能についての検討2008

    • Author(s)
      濱田晋、佐藤賢一、廣田衛久、菅野敦、海野純、伊藤広通、下瀬川徹
    • Organizer
      第50回日本消化器病学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-03
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Presentation] MSX2 promotes epithelial mesenchymal transition and associates with Twist 1 expression in human pancreatic cancer cells2007

    • Author(s)
      Kennichi Satoh, Shin Hamada, Kenji Kimura, Atsushi Kanno, Morihisa Hirota, Tooru Shimosegawa
    • Organizer
      DIGESTIVE DISEASE WEEK 2007
    • Place of Presentation
      Washington DC, U.S.A
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19590745
  • [Presentation] MSX2 promotes epithelial mesenchymal transition and associates with Twist 1 expression in human pancreatic cancer cells.2007

    • Author(s)
      Kennichi Satoh, Shin Hamada, Kenji Kimura, Atsushi Kanno, Morihisa Hirota, and Tooru Shimosegawa.
    • Organizer
      DIGESTIVE DISEASE WEEK 2007
    • Place of Presentation
      Washington DC
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19590745
  • 1.  SATOH Kennichi (10282055)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 2.  HAMADA Shin (20451560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  KANNO Atsushi (70509190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Masashi Tsuda (10312555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SYUNJI Mugikura (20375017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MATSUURA Tomonori (50623188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  高橋 伸一郎 (40375069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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