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Nomura Jun  野村 淳

… Alternative Names

NOMURA Jun  野村 淳

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Researcher Number 70406528
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0817-2643
Affiliation (Current) 2025: 神戸大学, 医学研究科, 客員准教授
Affiliation (based on the past Project Information) *help 2024: 神戸大学, 医学研究科, 助教
2023: 神戸大学, 医学研究科, 学内講師
2021 – 2022: 神戸大学, 医学研究科, 助教
2018 – 2019: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員
2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 … More
2013 – 2015: 広島大学, 医歯薬保健学研究院, 特任助教
2012 – 2013: 広島大学, 医歯薬保健学研究院(医), 特任助教
2006 – 2007: 埼玉医科大学, 医学部, 研究員 Less
Review Section/Research Field
Principal Investigator
Psychiatric science / Basic Section 49010:Pathological biochemistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Neurochemistry/Neuropharmacology
Except Principal Investigator
Pathological medical chemistry
Keywords
Principal Investigator
自閉症 / 精神疾患 / 疾患モデル / 発達障害 / ゲノム編集 / コピー数変異 / 染色体工学 / シングルセル解析 / コピー数多型 / 統合失調症 … More / 染色体操作 / ES細胞 / ジーンターゲティング / 翻訳 / 神経精神疾患 / 次世代シーケンサー / 神経発達障害 / 神経発達 / 神経生理 / 幹細胞生物学 / ヒトES細胞 / オルガノイド / 電気生理 / コピー数多型/CNV / 神経発達症 / コピー数多型(CNV) / ヒト型疾患モデル動物 / GABA / スパイン / モデルマウス / 薬理 / てんかん / 動物モデル / 神経変性疾患 / CNV / 精神神経疾患 / 脳神経疾患 … More
Except Principal Investigator
UTF1 / gene targeting / teratoma / cell growth / cellular differentiation / tumorigenic property / pluripotency / embryonic stem cells / ノックアウトマウス / ジーンテゲティング / 分化誘導 / 自己増殖性 / 全能性 / ジーンタゲティング / ジーンターゲティング / 奇形腫 / 細胞増殖 / 細胞分化 / 腫瘍原性 / 多能性 / ES細胞 Less
  • Research Projects

    (6 results)
  • Research Products

    (43 results)
  • Co-Researchers

    (3 People)
  •  Phase-specific risk analysis of the translation process in autismPrincipal Investigator

    • Principal Investigator
      野村 淳
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Kobe University
  •  Identifying drug targets for neuropsychiatric and neurodevelopmental disorders via brain transcriptomePrincipal Investigator

    • Principal Investigator
      NOMURA Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kobe University
  •  Develop and analysis for chromosome mutant micePrincipal Investigator

    • Principal Investigator
      Nomura Jun
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Comprehensive analysis for animal model of chromosome rearrangementPrincipal Investigator

    • Principal Investigator
      Nomura Jun
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Hiroshima University
  •  Analysis of mouse and cellular models of psychiatric disorders using a chromosome engineeringPrincipal Investigator

    • Principal Investigator
      NOMURA Jun
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Hiroshima University
  •  Role of embryonic stem cell-specific coacitvator UTF1 for tumorigenic property of ES cells

    • Principal Investigator
      OKUDA Akihiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Saitama Medical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2007 Other

All Journal Article Presentation Book

  • [Book] 自閉症学2019

    • Author(s)
      野村淳,内匠透
    • Total Pages
      234
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-17K07119
  • [Book] 今すぐ始めるゲノム編集2014

    • Author(s)
      野村淳,内匠透
    • Total Pages
      205
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Book] TALEN およびCRISPR/Cas9 を用いた染色体改変法 -簡便迅速かつ高効率な次世代染色体工学-, 実験医学別冊 今すぐ始めるゲノム編集2014

    • Author(s)
      野村淳, 内匠透
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Book] 自閉症のモデル動物, 自閉症の分子基盤, 分子精神医学, Vol.14, No.22014

    • Author(s)
      岸本恵子, 野村淳, 内匠透
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Book] 分子精神医学ー自閉症の分子基盤ー2014

    • Author(s)
      岸本恵子,野村淳,内匠透
    • Total Pages
      83
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Book] A 15q11-q13 duplication mouse model of autism spectrum disorders. -IV MODEL SYSTEMS AND PATHWAYS IN AUTISM SPECTRUM DISORDERS- The Neuroscience of Autism Spectrum Disorders2013

    • Author(s)
      Takumi T., Fukumoto K., Nomura J
    • Publisher
      Elsevier Inc
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Book] The Neuroscience of Autism Spectrum Disorders2012

    • Author(s)
      Takumi T, Fukumoto K, Nomura J
    • Total Pages
      496
    • Publisher
      Academic Press
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Journal Article] Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders2023

    • Author(s)
      Furukawa S, Nomura J, Hanafusa H, Maegawa H, Takumi T.
    • Journal Title

      Autism Research

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Journal Article] Germ‐cell‐specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders2023

    • Author(s)
      Furukawa Sawako、Nomura Jun、Hanafusa Hiroaki、Maegawa Hiroko、Takumi Toru
    • Journal Title

      Autism Research

      Volume: 16 Issue: 6 Pages: 1101-1110

    • DOI

      10.1002/aur.2939

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07820, KAKENHI-PUBLICLY-23H04233, KAKENHI-PROJECT-21H04813
  • [Journal Article] シングルセル,オルガノイド研究による細胞腫特異的自閉症リスク因子の同定2022

    • Author(s)
      Nomura J, Takumi T.
    • Journal Title

      日本生物学的精神医学会誌

      Volume: 33 Pages: 48-52

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Journal Article] A common pathologic mechanism across cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model.2022

    • Author(s)
      Lin C-W, Septyaningtrias DE, Chao H-W, Konda M, Atarashi K, Takeshita K, Tamada K, Nomura J, Sassagawa Y, Tanaka K, Nikaido I, Honda K, McHugh TL, Takumi T
    • Journal Title

      Mol Psychiatr

      Volume: in press Issue: 8 Pages: 3343-3354

    • DOI

      10.1038/s41380-022-01566-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06316, KAKENHI-PUBLICLY-21H00202, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21K19351, KAKENHI-PROJECT-21K07820, KAKENHI-PLANNED-21H05245, KAKENHI-PROJECT-19K16529
  • [Journal Article] Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability2022

    • Author(s)
      Nomura Jun、Zuko Amila、Kishimoto Keiko、Mutsumine Hiroaki、Fukatsu Kazumi、Nomura Yoshiko、Liu Xiaoxi、Nakai Nobuhiro、Takahashi Eiki、Kouno Tsukasa、Shin Jay W.、Takumi Toru、ES library team
    • Journal Title

      BioRxiv

      Volume: -

    • DOI

      10.1101/2022.02.02.478766

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Journal Article] Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia.2021

    • Author(s)
      Nomura J, Mardo M, Takumi T
    • Journal Title

      J Neurochem

      Volume: 159 Issue: 4 Pages: 647-659

    • DOI

      10.1111/jnc.15514

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06316, KAKENHI-PUBLICLY-21H00202, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21K07820, KAKENHI-PROJECT-21K19351
  • [Journal Article] Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion2021

    • Author(s)
      Nomura Yoshiko、Nomura Jun、Kamiguchi Hiroyuki、Nishikawa Toru、Takumi Toru
    • Journal Title

      Neuroscience Research

      Volume: N/A Pages: 114-123

    • DOI

      10.1016/j.neures.2021.03.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16H06316, KAKENHI-PUBLICLY-21H00202, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21K07820
  • [Journal Article] Reciprocal differentiation via GABAergic components and ASD-related phenotypes in hES with 1q21.1 CNV2021

    • Author(s)
      Nomura Yoshiko、Nomura Jun、Nishikawa Toru、Takumi Toru
    • Journal Title

      BioRxiv

      Volume: -

    • DOI

      10.1101/2021.09.13.460033

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Journal Article] Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches.2018

    • Author(s)
      Hui K, Katayama Y, Nakayama KI, Nomura J, Sakurai T.
    • Journal Title

      Neurosci. Biobehav. Rev.

      Volume: 印刷中 Pages: 30121-0

    • DOI

      10.1016/j.neubiorev.2018.08.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07119, KAKENHI-PROJECT-18K14822, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16K01948
  • [Journal Article] Role for neonatal D-serine signaling: prevention of physiological and bahavioral deficits in adult Pick1 knockout mice2016

    • Author(s)
      Nomura J, Jaaro-Peled H, Lewis E, Nunez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, O'Donnell P, Sawa A
    • Journal Title

      Mol Psychiatry

      Volume: 21 Issue: 3 Pages: 386-393

    • DOI

      10.1038/mp.2015.61

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23111005, KAKENHI-PROJECT-25242077, KAKENHI-PROJECT-26870397
  • [Journal Article] Involvement of Serotonin Transporter Gene Polymorphisms (5-HTT) in Impulsive Behavior in the Japanese Population2015

    • Author(s)
      NOMURA, M., KANEKO, M., OKUMA, Y., NOMURA, J., KUSUMI, I., KOYAMA, T., NOMURA, Y
    • Journal Title

      PLoS One

      Volume: 16 Issue: 3 Pages: 1-14

    • DOI

      10.1371/journal.pone.0119743

    • NAID

      120005745671

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26870397, KAKENHI-PROJECT-15K00205, KAKENHI-PROJECT-15K21706
  • [Journal Article] Animal models of psychiatric disorders that reflect human copy number variation2012

    • Author(s)
      Nomura J and Takumi T
    • Journal Title

      Neural plasticity

      Volume: 2012 Pages: 1-9

    • DOI

      10.1155/2012/589524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791212, KAKENHI-PLANNED-23111005
  • [Journal Article] Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion2012

    • Author(s)
      Ma TM, Abazyan S, Abazyan B, Nomura J, Yang C, Seshadri S, Sawa A, Snyder SH, Pletnikov MV
    • Journal Title

      Molecular Psychiatry

      Volume: 18 Issue: 5 Pages: 557-567

    • DOI

      10.1038/mp.2012.97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Journal Article] Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference : a comorbidity model2012

    • Author(s)
      Pogorelov VM, Nomura J, Kim J, Kannan G, Ayhan Y, Yang C, Taniguchi Y, Abazyan B, Valentine H, Krasnova IN, Kamiya A, Cadet JL, Wong DF, Pletnikov MV
    • Journal Title

      Neuropharmacology

      Volume: 62 Issue: 3 Pages: 1242-1251

    • DOI

      10.1016/j.neuropharm.2011.02.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Presentation] Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability2023

    • Author(s)
      Nomura J. Takumi T
    • Organizer
      The 2nd International Symposium Multiscale Brain / MCCS-Asia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] ES cell models of autism with copy number variations reveal cell-type-specific vulnerability2023

    • Author(s)
      Nomura J.
    • Organizer
      The 1st NSN (Neuroscience Network in Kobe) Research Seminar 2023
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] Autism in a Dish.2023

    • Author(s)
      NOMURA, J., TAKUMI, T.
    • Organizer
      The 64th Annual Meeting of the Japanese Society of Neuropathology, The 66th Annual Meeting of the Japanese Society for Neurochemistry
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] 細胞モデルを用いた結節性硬化症の病態シグナル解析2023

    • Author(s)
      野村淳, 内匠透,
    • Organizer
      第11回日本結節性硬化症学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] 神経発達症と相関する染色体領域改変マウスの表現型解析2023

    • Author(s)
      野村淳, 内匠透
    • Organizer
      科学技術振興機構 ムーンショット型研究開発事業目標9: 第2回マウスの会
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] Brain Science of Neurodevelopmental Disorders.,2023

    • Author(s)
      NOMURA, J., TAKUMI, T.
    • Organizer
      The 11thCongress of The Asian Society for Child and Adolescent Psychiatry & Allied Professions (ASCAPAP).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] Autism in a dish., Comprehensive analysis identified CNV- and cell type specific vulnerability of autism spectrum disorder.2023

    • Author(s)
      Nomura J, Takumi T.
    • Organizer
      第4回理化学研究所BDR・神戸大学合同シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] ES cell models of autism with copy number variations reveal cell-type-specific vulnerability,2023

    • Author(s)
      野村淳
    • Organizer
      The 7th NSN Kobe (Neuroscience Network in Kobe) Research Seminar
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07820
  • [Presentation] Comprehensive analysis identified CNV- and cell type specific vulnerability across psychiatric disorders2020

    • Author(s)
      Jun Nomura
    • Organizer
      Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07119
  • [Presentation] ヒト染色体15q13.3コピー数多型モデルの統合的解析 ーヒト染色体15q13.3コピー数多型モデルのトランスクリプトーム解析ー2019

    • Author(s)
      Jun Nomura
    • Organizer
      喫煙財団研究発表会
    • Data Source
      KAKENHI-PROJECT-17K07119
  • [Presentation] Phenotypic analysis of a mouse model for 15q25.2-25.3 deletion syndrome.2017

    • Author(s)
      Nomura, Jun; Kanda, Akifumi; Ellegood, Jacob; Lerch, Jason; Sotomaru, Yusuke; Takumi, Toru
    • Organizer
      26th Annual Meeting of the International Behavioral Neuroscience Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07119
  • [Presentation] Brain structural and behavioral abnormalities in a mouse model for 15q25.2-25.3 microdeletion syndrome2017

    • Author(s)
      Nomura, Jun; Kanda, Akifumi; Ellegood, Jacob; Lerch, Jason; Sotomaru, Yusuke; Takumi, Toru
    • Organizer
      第60回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17K07119
  • [Presentation] 発達期における D- セリンの役割:Pick1 ノックアウトマウスをモデルとして2015

    • Author(s)
      Nomura J, Jaaro-Peled H, Lewis E, Nunez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, O'Donnell P, Sawa A.
    • Organizer
      第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
    • Place of Presentation
      東京(タワーホール船堀)
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-26870397
  • [Presentation] D-serine production is modulated by DISC1 and Serine racemase interaction in astrocytes, 11th Biennial Meeting of the Asian Pacific Society for Neurochemistry2012

    • Author(s)
      Nomura J, Ma TM, Abazyan S, Abazyan B, Seshadri S, Sawa A, Snyder SH, Pletnikov MV
    • Organizer
      55th Annual Meeting of the Japanese Society for Neurochemistry
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2012-10-01
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Presentation] DISC1 and serine racemase interact in astrocytes to regulate D-serine production2012

    • Author(s)
      Abazyan B, Ma TM, Nomura J, Abazyan S, Sawa A, Snyder SH, Pletnikov MV
    • Organizer
      3rd Biennial Schizophrenia International Research Conference
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2012-04-15
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Presentation] D-serine production is modulated by DISC1 and Serine racemase interaction in astrocytes2012

    • Author(s)
      Nomura J, Ma TM, Abazyan S, Abazyan B, Seshadri S, Sawa A, Snyder SH, Pletnikov MV
    • Organizer
      11th Biennial Meeting of the Asian Pacific Society for Neurochemistry, 55th Annual Meeting of the Japanese Society for Neurochemistry
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Presentation] DISC1 interacts with Serine racemase to modulate D-serine production in astrocytes2012

    • Author(s)
      Pletnikov MV, Ma TM, Nomura J, Abazyan B, Abazyan S, Sawa A, Snyder SH
    • Organizer
      3rd Biennial Schizophrenia International Research Conference
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2012-04-18
    • Data Source
      KAKENHI-PROJECT-24791212
  • [Presentation] Nucleostemin遺伝子の各種幹細胞における機能2007

    • Author(s)
      野村 淳
    • Organizer
      第30回日本分子生物学会、第80回日本生化学会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390106
  • [Presentation] Nucleostemin遺伝子の各種幹細胞における機能2007

    • Author(s)
      野村 淳
    • Organizer
      第30回日本分子生物学会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-18390106
  • [Presentation] Role of Nucleostemin in ES cells and Somatic Stem Cells2007

    • Author(s)
      Jun, Nomura
    • Organizer
      Biochemistry and Molecular Biology 2007
    • Place of Presentation
      Pacifico Yokohama, InterContinental Yokohama Grand
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390106
  • [Presentation] ゲノム編集技術による簡便迅速かつ高効率な次世代染色体工学の開発

    • Author(s)
      野村 淳, 佐久間 哲史, 神田 暁史, 岸本 恵子, 前田 知花, 外丸 祐介, 山本 卓, 内匠 透
    • Organizer
      第37回分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26870397
  • [Presentation] ゲノム編集技術による簡便迅速かつ高効率な次世代染色体工学の開発

    • Author(s)
      野村 淳, 佐久間 哲史, 神田 暁史, 岸本 恵子, 前田 知花, 外丸 祐介, 山本 卓, 内匠 透
    • Organizer
      第4回ゲノム編集研究会
    • Place of Presentation
      広島
    • Year and Date
      2014-10-06 – 2014-10-07
    • Data Source
      KAKENHI-PROJECT-26870397
  • 1.  OKUDA Akihiko (60201993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  MITANI Kohnosuke (10270901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  内匠 透
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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