Kobayashi Keiichi 小林啓一

… Alternative Names

小林啓一コバヤシケイイチ

KOBAYASHI Keiichi 小林啓一

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Researcher Number	70406990
Affiliation (Current)	2025: 杏林大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 杏林大学, 医学部, 講師 2017 – 2021: 杏林大学, 医学部, 学内講師 2015 – 2016: 杏林大学, 医学部, 助教 2007 – 2011: Kyorin University, 医学部, 助教 2006: 杏林大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Neurosurgery
Keywords	Principal Investigator 中枢神経系悪性リンパ腫 / liquid biopsy / CNS lymphoma / CD79B / MYD88 / マルチプレックスqPCR / リキッドバイオプシー / 分子遺伝子学 / 脳腫瘍 / 二次性悪性リンパ腫 … More / メチル化アレイ / 遺伝子変異解析 / 二次性中枢神経系悪性リンパ腫 / パイロシーケンス / 幹細胞 / IGFBP2 / MGMT / パイロシークエンス / メチル化 / 神経膠腫 / 悪件脳腫瘍 / アポトーシス / temozolomide / CD133 / neurosphere / 薬剤耐性 / 悪性脳腫瘍 / 脳腫瘍幹細胞 / siRNA / inhibitor / 4F2hc / LAT1 / glioma / amino acid transporter Less

A prospective study on the diagnosis of central nervous system lymphoma by the detection of specific genetic mutations in cerebrospinal fluid DNAPrincipal Investigator
- Principal Investigator
  
  Kobayashi Keiichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyorin University
Comparative genetic analysis of central nervous system lymphomas between sites in the central nervous system or extracranial organsPrincipal Investigator
- Principal Investigator
  
  Kobayashi Keiichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyorin University
Novel methylation markers of glioma and glioma stemcell and their application to individualized medicinePrincipal Investigator
- Principal Investigator
  
  Kobayashi Keiichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyorin University
Investigation of mechanisms of drug resistance in malignant brain tumor stem cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Keiichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyorin University
Targeting of neutral amino acid transporters as a novel therapeutic strategy for malignant gliomaPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Keiichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyorin University

All 2023 2022 2021 2020 2017 2016 2015 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] 脳腫瘍のsurrogate marker中枢神経系リンパ腫のサロゲートマーカーとしての髄液中MYD88変異検出の意義2022
- Author(s)
  山岸夢希，佐々木重嘉，齊藤邦昭，小林啓一，中冨浩文，近藤聡英，塩川芳昭, 成田善孝，市村幸一，永根基雄
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 39 Suppl Pages: 63-63
- Data Source
  KAKENHI-PROJECT-21K09136
[Journal Article] Consecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy2020
- Author(s)
  Sasaki N, Kobayashi K, Saito K, Shimizu S, Suzuki K, Lee J, Yamagishi Y, Shibahara J, Takayama N, Shiokawa Y, Nagane M
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: inpress Issue: 9 Pages: 1-11
- DOI
  10.1093/jjco/hyaa073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10873, KAKENHI-PROJECT-16H05442, KAKENHI-PROJECT-18K08950
[Journal Article] 初発悪性神経膠腫に対するアルキル化剤別放射線併用化学療法の治療成績2012
- Author(s)
  林基高, 永根基雄, 小林啓一, 塩川芳昭
- Journal Title
  
  Neuro-Oncology (Tokyo)
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] テモゾロミド不応性悪性神経膠腫に対するアバスチン単独療法の治療効果2012
- Author(s)
  永根基雄, 小林啓一, 林基高, 佐藤研隆, 塩川芳昭
- Journal Title
  
  Neuro-Oncology (Tokyo)
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] Predictive value of mean apparent diffusion co-efficient value for respon siveness of temozolomide-refractory malignant glioma to bevacizumab2011
- Author(s)
  Nagane M, Kobayashi K, Tanaka M, Tsuchiya K, Shiokawa Y
- Journal Title
  
  J Clin Oncol
  
  Volume: 29: suppl
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] Predictive value of mean apparent diffusion co-efficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab2011
- Author(s)
  Nagane M, Kobayashi K, Tanaka M, Tsuchiya K, Shiokawa Y
- Journal Title
  
  J Clin Oncol
  
  Volume: 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] 高齢者初発膠芽腫に対する放射線化学療法の治療成績と因子解析2011
- Author(s)
  永根基雄, 小林啓一, 林基高, 清水早紀, 塩川芳昭
- Journal Title
  
  Geriatric Neurosurgery
  
  Volume: 23 Pages: 3-11
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] 脳腫瘍の疫学と分類2011
- Author(s)
  小林啓一, 永根基雄
- Journal Title
  
  J Clin Rehab
  
  Volume: 20 Pages: 154-157
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] テモゾロミド不応性悪性神経膠腫に対するベバシツマブ単独療法の治療効果2010
- Author(s)
  永根基雄, 小林啓一, 林基高, 佐藤研隆, 土屋一洋、塩川芳昭
- Journal Title
  
  脳外誌
  
  Volume: 19 Pages: 758-766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] 仲枢神経系リンパ腫に対する大量MTX療法単独による初期治療の検討2010
- Author(s)
  小林啓一、永根基雄、塩川芳昭
- Journal Title
  
  Neuro-Oncology(Tokyo) (In press)
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] 再発悪性神経膠腫に対するcarboplatin/etoposide併用療法2010
- Author(s)
  横矢重臣、永根基雄、小林啓一, ら
- Journal Title
  
  Neuro-Oncology(Tokyo) (In press)
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] 悪性脳腫瘍～開頭腫瘍摘出術2010
- Author(s)
  小林啓一
- Journal Title
  
  BRAIN NURSING
  
  Volume: 26 Pages: 40-43
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] 中枢神経系リンパ腫に対する大量MTX療法単独による初期治療の検討2009
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Journal Title
  
  Neuro-Oncology(Tokyo) (In press)
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 再発悪性神経膠腫に対するcarboplatin/etoposide併用療法2009
- Author(s)
  横矢重臣, 永根基雄, 小林啓一, 塩川芳昭
- Journal Title
  
  Neuro-Oncology(Tokyo) (In press)
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 転移性脳腫瘍2009
- Author(s)
  小林啓一, 永根基雄
- Journal Title
  
  In Clinical Neuroscience Vol 27 (6)
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 転移性脳腫瘍2009
- Author(s)
  小林啓一、永根基雄
- Journal Title
  
  Clinical Neuroscience 27
  
  Pages: 698-700
- Data Source
  KAKENHI-PROJECT-21591880
[Journal Article] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells2008
- Author(s)
  Kobayashi K, Ohnishi A, Promsuk J, Shimizu S, Kanai Y, Shiokawa Y, Nagane M
- Journal Title
  
  Neurosurgery 62 (2)
  
  Pages: 493-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells2008
- Author(s)
  Kobayashi K, et. al.
- Journal Title
  
  Neurosurgery 62
  
  Pages: 493-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells2008
- Author(s)
  Kobayashi K, Ohnishi A, Promsuk J, Shimizu S, Kanai Y, Shiokawa Y, Nagane M
- Journal Title
  
  Neurosurgery 62
  
  Pages: 493-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 初発悪性神経膠腫に対する術後放射線併用PAV変法療法2007
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Journal Title
  
  Neuro-Oncology (Tokyo) 17 (1)
  
  Pages: 33-35
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] Prognostic significance of O^6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide2007
- Author(s)
  Nagane M, Kobayashi K, Ohnishi A, Shimizu S, Shiokawa Y
- Journal Title
  
  Jpn J Clin Oncol 37(12)
  
  Pages: 897-906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells2007
- Author(s)
  Kobayashi K, et al.
- Journal Title
  
  Neurosurgery (in press)
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 再発悪性神経膠腫に対するCarboplatin/高圧酸素併用療法の治療経験-palliatiion療法の可能性2006
- Author(s)
  小林啓一, 永根基雄ら
- Journal Title
  
  日本臨床高気圧酸素・潜水病学会誌 3
  
  Pages: 37-41
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 再発悪性神経膠腫に対するCarboplatin/高圧酸素併用療法の治療経験palliation 療法の可能性2006
- Author(s)
  小林啓一, 永根基雄, 藤井芳樹, 塩川芳昭
- Journal Title
  
  日本臨床高気圧酸素・潜水病学会誌 3
  
  Pages: 37-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 再発中枢神経系リンパ腫に対するsecond line PAV療法2006
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Journal Title
  
  Neuro-Oncology (Tokyo) 16(2)
  
  Pages: 74-77
- Data Source
  KAKENHI-PROJECT-18591606
[Journal Article] 再発悪性神経膠腫に対するtemozolomide 単独療法の治療成績2006
- Author(s)
  永根基雄, 小林啓一, 塩川芳昭
- Journal Title
  
  Neuro-Oncology (Tokyo) 16(2) 16(2)
  
  Pages: 26-29
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] Clinical applicability of digital PCR-based liquid biopsy for detecting MYD88 L265P mutation in cerebrospinal fluid in patients with primary CNS lymphoma2023
- Author(s)
  Motoo Nagane, Yuki Yamagishi, Nobuyoshi Sasaki, Saki Shimizu, Yuko Matsushita, Kuniaki Saito, Keiichi Kobayashi, Hirofumi Nakatomi, Yoshiaki Shiokawa, Yoshitaka Narita, Koichi Ichimura
- Organizer
  International Conference of Brain Tumor Research and Therapy 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09136
[Presentation] 髄液中MYD88検出による中枢神経系悪性リンパ腫のサロゲートマーカーとしての有用性2023
- Author(s)
  山岸夢希，佐々木重嘉，清水早紀，松下裕子，齊藤邦昭，小林啓一，中冨浩文，塩川芳昭，成田善孝，市村幸一，永根基雄
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09136
[Presentation] 脳脊髄液による中枢神経系リンパ腫の診断2022
- Author(s)
  永根基雄、山岸夢希、小林啓一、他
- Organizer
  第6回Liquid Biopsy研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09136
[Presentation] 中枢神経系リンパ腫のサロゲートマーカーとしての髄液中MYD88変異検出の意義2022
- Author(s)
  山岸夢希，佐々木重嘉，清水早紀，松下裕子，齊藤邦昭，小林啓一，中冨浩文，近藤聡英，塩川芳昭，成田善孝，市村幸一，永根基雄
- Organizer
  第40回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-21K09136
[Presentation] 中枢神経系原発悪性リンパ腫に対するMYD88変異検出による髄液liquid biopsy2021
- Author(s)
  山岸夢希、佐々木重嘉、小林啓一、市村幸一、永根基雄、他
- Organizer
  第39回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09136
[Presentation] 再発中枢神経系原発悪性リンパ腫に対するRMPVA療法の治療成績と展望2020
- Author(s)
  永根基雄、佐々木重嘉、小林啓一、齊藤邦昭、島田大輔、松本淑恵、飯島昌平、山岸夢希、清水早紀、佐々木佑太、塩川芳昭
- Organizer
  日本脳神経外科学会第79回学術集会
- Data Source
  KAKENHI-PROJECT-18K08950
[Presentation] Combined rituximab, methotrexate, procarbazine, vincristine, and cytarabine (R-MPV-A) treatment for patients with relapsed primary CNS lymphoma2020
- Author(s)
  Motoo Nagane, Nobuyoshi Sasaki, Keiichi Kobayashi, Kuniaki Saito, Daisuke Shimada, Yoshie Matsumoto, Shohei Iijima, Yuki Yamagishi, Saki Shimizu, Yuta Sasaki, Nobuyuki Takayama, Yoshiaki Shiokawa
- Organizer
  25th Annual Meeting of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08950
[Presentation] 再発中枢神経系原発悪性リンパ腫に対する薬物療法の治療成績と展望2020
- Author(s)
  永根基雄、佐々木重嘉、小林啓一、齊藤邦昭、島田大輔、松本淑恵、飯島昌平、山岸夢希、清水早紀、佐々木佑太、塩川芳昭
- Organizer
  第38回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08950
[Presentation] Integrated molecular analysis of newly diagnosed and recurrent glioblastoma after temozolomide treatment2017
- Author(s)
  Kuniaki Saito, Saki Shimizu, Kaori Suzuki, Keiichi Kobayashi, Daisuke Shimada, Satosi Kume, Shohei Iijima, Tomohiro Chiba, Junji Shibahara, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  第35回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Temozolomide-induced mismatch repair insufficiency and hypermethylation of MGMT promoter with hypermutation in malignant glioma2017
- Author(s)
  Kuniaki Saito, Saki Shimizu, Kaori Suzuki, Keiichi Kobayashi, Daisuke Shimada, Satosi Kume, Shohei Iijima, Tomohiro Chiba, Junji Shibahara, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  22nd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Prognostic significance of MGMT promoter and mismatch repair system in newly-diagnosed and recurrent malignant gliomas2017
- Author(s)
  Kuniaki Saito, Saki Shimizu, Kaori Suzuki, Keiichi Kobayashi, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  5th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies (WFNOS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Goal-setting of extent of resection on the basis of molecular status in glioma surgery2017
- Author(s)
  Kuniaki Saito, Kaori Suzuki, Saki Shimizu, Keiichi Kobayashi, Daisuke Shimada, Zentaro Kawaida, Kazuhiro Chiba, Junji Shibahara, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  第76回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Integrated molecular analysis of newly diagnosed and recurrent glioblastoma after temozolomide treatment2017
- Author(s)
  Kuniaki Saito, Kaori Suzuki, Saki Shimizu, Keiichi Kobayashi, Daisuke Shimada, Zentaro Kawaida, Tomohiro Chiba, Junji Shibahara, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  第35回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Integrated analysis of MGMT promoter methylation and mismatch repair alteration in glioma2016
- Author(s)
  Kuniaki Saito, Saki Shimizu, Kaori Suzuki, Keiichi Kobayashi, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Integrated analysis of methylation of MGMT promoter and alteration of mismatch repair enzymes in glioblastoma2016
- Author(s)
  Motoo Nagane, Kuniaki Saito, Keiichi Kobayashi, Saki Shimizu, Kaori Suzuki, Nobuyoshi Sasaki, Satoshi Kume, Yuki Yamagishi, Yoshiaki Shiokawa
- Organizer
  13th Asian Society for Neuro-Oncology Meeting
- Place of Presentation
  Sydney, Australia
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Mismatch Repair defects predict clinical outcome of primary and recurrent malignant gliomas2015
- Author(s)
  Kuniaki Saito, Saki Shimizu, Kaori Suzuki, Keiichi Kobayashi, Nobuyoshi Sasaki, Satoshi Kume, Yoshiaki Shiokawa, Motoo Nagane
- Organizer
  20th Annual Scientific Meeting of the Society for Neuro-Oncology
- Place of Presentation
  San Antonio, USA
- Year and Date
  2015-11-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] MGMTメチル化とDNAミスマッチ修復酵素の異常に応じた膠芽腫治療の展望2015
- Author(s)
  齊藤邦昭、小林啓一、清水早紀、鈴木香、佐々木重嘉、久米賢、塩川芳昭、永根基雄
- Organizer
  第74回日本脳神経外科学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] ミスマッチ修復酵素異常が初発膠芽腫の予後に与える影響2015
- Author(s)
  齊藤邦昭、小林啓一、清水早紀、鈴木香、川井田善太郎、今井大也、塩川芳昭、永根基雄
- Organizer
  第24回多摩脳腫瘍研究会
- Place of Presentation
  東京
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] 低悪性度神経膠腫再発時におけるMGMTメチル化/ミスマッチ修復タンパク発現の変化2015
- Author(s)
  齊藤邦昭、小林啓一、清水早紀、鈴木香、佐々木重嘉、久米賢、塩川芳昭、永根基雄
- Organizer
  第29回東京脳腫瘍治療懇話会
- Place of Presentation
  東京
- Year and Date
  2015-06-19
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] 神経膠腫におけるMGMTメチル化とDNAミスマッチ修復酵素の統合解析2015
- Author(s)
  齊藤邦昭、小林啓一、清水早紀、鈴木香、佐々木重嘉、久米賢、川井田善太郎、塩川芳昭、永根基雄
- Organizer
  第33会日本脳腫瘍学会学術集会
- Place of Presentation
  京都
- Year and Date
  2015-12-07
- Data Source
  KAKENHI-PROJECT-15K10342
[Presentation] Antiangiogenic therapy for recurrent malignant glioma by bevacizumab monotherapy-Efficacy and future prospective-2011
- Author(s)
  Motoo Nagane, Keiichi Kobayashi, Masaki Tanaka, Kazuhiro Tsuchiya, Yukiko Shishido-Hara, Yoshiaki Shiokawa
- Organizer
  29th Annual Meeting of Japan Society for Neuro-Oncology
- Place of Presentation
  Gero, Gifu, Japan
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] Predictive value of mean apparent diffusion coefficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab2011
- Author(s)
  Motoo Nagane, Keiichi Kobayashi, Masaki Tanaka, Kazuhiro Tsuchiya, Yoshiaki Shiokawa
- Organizer
  The 16th Annual Meeting of the Society for Neuro-Oncology
- Place of Presentation
  Anaheim, CA, U.S.A
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 再発悪性神経膠腫に対する定位的放射線療法の治療効果2011
- Author(s)
  小林啓一、永根基雄、丸山啓介、戸成綾子、永山和樹、野村龍太郎、佐藤健吾、高山誠、塩川芳昭
- Organizer
  ニューロオンコロジイの会
- Place of Presentation
  東京
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 術中ナビゲーションにおけるT2反転および錐体路・PET画像融合の有用性2011
- Author(s)
  小林啓一、丸山啓介、田中雅樹、野口明男、土屋一洋、永根基雄、塩川芳昭
- Organizer
  第16回日本脳腫瘍の外科学会
- Place of Presentation
  横浜
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] Antiangiogenic therapy for recurrent malignant glioma by bevacizumab monotherapy---Efficacy and future prospective---2011
- Author(s)
  Motoo Nagane, Keiichi Kobayashi, Masaki Tanaka, Kazuhiro Tsuchiya, Yukiko Shishido-Hara, Yoshiaki Shiokawa
- Organizer
  29^<th> Annual Meeting of Japan Society for Neuro-Oncology
- Place of Presentation
  Gero, Gifu, Japan
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 再発悪性神経膠腫に対する定位的放射線療法の治療効果2011
- Author(s)
  小林啓一、永根基雄、丸山啓介、戸成綾子、永山和樹、野村龍太郎、佐藤健吾、高山誠、塩川芳昭
- Organizer
  第29回日本脳腫瘍学会
- Place of Presentation
  下呂、岐阜
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 中枢神経系原発悪性リンパ腫に対するPAV療法の使用経験2011
- Author(s)
  小林啓一、永根基雄、田中雅樹、塩川芳昭
- Organizer
  第29回日本脳腫瘍学会
- Place of Presentation
  下呂、岐阜
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 再発悪性神経膠腫に対する血管新生標的治療:ベバシツマブ単独療法の効果と問題点2011
- Author(s)
  永根基雄, 小林啓一, 田中雅樹, 土屋一洋, 原由紀子, 塩川芳昭
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] Predictive value of mean apparent diffusion co-efficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab2011
- Author(s)
  Motoo Nagane, Keiichi Kobayashi, Masaki Tanaka, Kazuhiro Tsuchiya, Yoshiaki Shiokawa
- Organizer
  2011 Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 術中ナビゲーションにおけるT2反転および錐体路・PET画像融合の有用性2010
- Author(s)
  小林啓一、田中雅樹、丸山啓介、野口明男、土屋一洋、永根基雄、塩川芳昭
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 腫瘍内出血を繰り返した右前頭葉腫瘍の一例2010
- Author(s)
  小林啓一, 他
- Organizer
  第14回多摩脳腫瘍研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 悪性神経膠腫に対する化学療法によるリンパ球減少など血液毒性の評価と問題点2010
- Author(s)
  小林啓一, 他
- Organizer
  第48回癌治療学会
- Place of Presentation
  京都
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 悪性神経膠腫に対する化学療法によるリンパ球減少など血液毒性の評価と問題点2010
- Author(s)
  小林啓一, 他
- Organizer
  第48回癌治療学会
- Place of Presentation
  長野県軽井沢
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 中枢神経系原発悪性リンパ腫に対するステロイド及びHD-MTX療法の治療効果の関連と予後解析2010
- Author(s)
  小林啓一, 他
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  長野県軽井沢
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 診断に難渋した大脳皮質下主座脳室上衣下浸潤を認める脳腫瘍性病変の一生検.剖検例2010
- Author(s)
  小林啓一, 他
- Organizer
  第28回脳腫瘍病理学会
- Place of Presentation
  大阪
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 初発中枢神経系原発悪性リンパ腫に対するステロイド及びHD-MTX療法の治療効果と臨床学的因子の検討2010
- Author(s)
  小林啓一, 他
- Organizer
  第40回ニューロオンコロジィの会
- Place of Presentation
  東京
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 悪性神経膠腫に対する化学療法によるリンパ球減少など血液毒性の評価と問題点2010
- Author(s)
  小林啓一, 他
- Organizer
  第69回脳神経外科学会総会
- Place of Presentation
  博多
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 迅速診断が困難であった右前頭葉腫瘍の一例2010
- Author(s)
  小林啓一, 他
- Organizer
  第13回多摩脳腫瘍研究会
- Place of Presentation
  東京
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] 再発膠芽腫に対するtemozolomide療法効果とMGMT解析法の検討2009
- Author(s)
  永根基雄, 小林啓一, 清水早紀, Andreas Waha, 塩川芳昭
- Organizer
  第4回脳腫瘍の基礎シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-01-31
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] Combination Therapy with Carboplatin and Etoposide for Recurrent Malignant Gliomas2009
- Author(s)
  Kobayashi, K, et al
- Organizer
  The 3^<rd> WFNO/The 6^<th> ASNO
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-21591880
[Presentation] MGMT解析によるtemozolomide療法効果の検討2008
- Author(s)
  永根基雄, 小林啓一, 清水早紀, 水谷徹, Andreas Waha, 塩川芳昭
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  松山
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 術中モニターリング及び術中蛍光診断を併用したナビゲーション下神経膠腫摘出術~摘出率向上をめざして2008
- Author(s)
  小林啓一
- Organizer
  第13回日本脳腫瘍の外科学会
- Place of Presentation
  大阪
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 低悪性度乏突起膠腫系腫瘍に対する化学療法単独による初期治療の検討2008
- Author(s)
  永根基雄, 小林啓一, 清水早紀, 塩川芳昭
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  松山
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 中枢神経系リンパ腫に対する大量MTX 療法単独による初期治療の検討2008
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  松山
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 難治性てんかんに対する外科的治療後に発症した膠芽腫の一例2008
- Author(s)
  小林啓一, 永根基雄, 林基高, 栗田浩樹, 須永茂樹, 清水弘之, 新井信隆, 水谷俊雄, 藤岡保範, 塩川芳昭
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 中枢神経系リンパ腫に対する大量MTX療法単独による初期治療の検討2008
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  松山
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 中枢神経系リンパ腫に対する大量MTX療法単独による初期治療の検討2008
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Organizer
  第36回ニューロオンコロジイの会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] Enhanced tumor growth elicited by L-type amino acid transporter l in human malignant glioma cells. The 17th International Conference on Brain Tumor Research and Therapy2008
- Author(s)
  Motoo Nagane, Keiichi Kobayashi, Akiko Ohnishi, Katsuyoshi Kanai, Yoshiaki Shiokawa
- Organizer
  The 17th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate, Hokkaido
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells2008
- Author(s)
  Motoo Nagane, Keiichi Kobayashi, Akiko Ohnishi, Katsuyoshi Kanai, Yoshiaki Shiokawa
- Organizer
  The 17th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate, Hokkaido, Japan
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 杏林大学における転移性脳腫瘍治療の現況2008
- Author(s)
  小林啓一, 永根基雄, 永山和樹, 塩川芳昭
- Organizer
  第67回日本脳神経外科学会
- Place of Presentation
  岩手
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 治療に難渋している播種性再発髄芽腫の1例2008
- Author(s)
  小林啓一, 永根基雄, 横矢重臣, 湯山隆次,水谷徹,塩川芳昭
- Organizer
  東京脳腫瘍治療懇話会
- Place of Presentation
  東京
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 杏林大学における転移性脳腫瘍治療の現況2008
- Author(s)
  小林啓一, 永根基雄, 永山和樹, 塩川芳昭
- Organizer
  第10回多摩脳腫瘍研究会
- Place of Presentation
  三鷹
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 膠芽腫に対するtemozolomide療法における予測因子MGMT statusの解析法の検討2008
- Author(s)
  永根基雄, 小林啓一, 清水早紀, 水谷徹, 塩川芳昭
- Organizer
  第67回日本脳神経外科学会総会
- Place of Presentation
  盛岡
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 膠芽腫に対するtemozolomide療法におけるMGMT解析法の検討2008
- Author(s)
  永根基雄, 小林啓一, 清水早紀, 水谷徹, 塩川芳昭
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 初発悪性生星細胞腫に対する術後放射線併用PAV変法療法2007
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Organizer
  第33回ニューロオンコロジイの会
- Place of Presentation
  東京
- Year and Date
  2007-04-07
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 血液内科での化学療法が奏功した頭皮下リンパ腫の3例2007
- Author(s)
  小林啓一, 永根基雄, 甫守正史, 栗田浩樹, 藤岡保範, 塩川芳昭
- Organizer
  第35回多摩脳神経外科懇話会
- Place of Presentation
  吉祥寺
- Year and Date
  2007-06-07
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] R-CHOP療法が著功した硬膜病変を伴う頭皮下リンパ腫の3症例2007
- Author(s)
  小林啓一, 永根基雄, 甫守正史, 栗田浩樹, 藤岡保範, 土屋一洋, 塩川芳昭
- Organizer
  第66回日本脳神経外科学会総会
- Place of Presentation
  東京
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-18591606
[Presentation] 初発悪性生星細胞腫に対する術後放射線併用PAV変法療法2007
- Author(s)
  小林啓一, 永根基雄, 塩川芳昭
- Organizer
  第45回日本癌治療学会総会
- Place of Presentation
  京都
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-18591606

1. NAGANE Motoo (60327468)

# of Collaborated Projects: 6 results

# of Collaborated Products: 70 results
2. 市村幸一 (40231146)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. SHIMIZU Saki

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. HARA Yukiko (40313267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SAITO Kuniaki (50446564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
6. 佐々木重嘉 (20894504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. SHIOKAWAYOSHIAKI Shiokawa Yoshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Keiichi 小林 啓一

小林 啓一 コバヤシ ケイイチ

KOBAYASHI Keiichi 小林 啓一

Research Projects

Research Products

Co-Researchers

A prospective study on the diagnosis of central nervous system lymphoma by the detection of specific genetic mutations in cerebrospinal fluid DNAPrincipal Investigator

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Comparative genetic analysis of central nervous system lymphomas between sites in the central nervous system or extracranial organsPrincipal Investigator

Principal Investigator

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Novel methylation markers of glioma and glioma stemcell and their application to individualized medicinePrincipal Investigator

Principal Investigator

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Research Institution

Investigation of mechanisms of drug resistance in malignant brain tumor stem cellsPrincipal Investigator

Principal Investigator

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Targeting of neutral amino acid transporters as a novel therapeutic strategy for malignant gliomaPrincipal Investigator

Principal Investigator

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[Journal Article] 脳腫瘍のsurrogate marker中枢神経系リンパ腫のサロゲートマーカーとしての髄液中MYD88変異検出の意義2022

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[Journal Article] Consecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy2020

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[Journal Article] 初発悪性神経膠腫に対するアルキル化剤別放射線併用化学療法の治療成績2012

Author(s)

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Data Source

[Journal Article] テモゾロミド不応性悪性神経膠腫に対するアバスチン単独療法の治療効果2012

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[Journal Article] Predictive value of mean apparent diffusion co-efficient value for respon siveness of temozolomide-refractory malignant glioma to bevacizumab2011

Author(s)

Journal Title

Data Source

[Journal Article] Predictive value of mean apparent diffusion co-efficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab2011

Author(s)

Journal Title

Data Source

[Journal Article] 高齢者初発膠芽腫に対する放射線化学療法の治療成績と因子解析2011

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[Journal Article] 脳腫瘍の疫学と分類2011

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[Journal Article] テモゾロミド不応性悪性神経膠腫に対するベバシツマブ単独療法の治療効果2010

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Journal Title

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[Journal Article] 仲枢神経系リンパ腫に対する大量MTX療法単独による初期治療の検討2010

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[Journal Article] 再発悪性神経膠腫に対するcarboplatin/etoposide併用療法2010

Author(s)

Journal Title

Kobayashi Keiichi 小林啓一

小林啓一コバヤシケイイチ

KOBAYASHI Keiichi 小林啓一