Takata Fuyuko 高田芙友子

… Alternative Names

TAKATA Fuyuko 高田芙友子

高田芙友子タカタフユコ

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Researcher Number	70412575
Other IDs
Affiliation (Current)	2025: 福岡大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 福岡大学, 薬学部, 准教授 2009 – 2018: Fukuoka University, 薬学部, 助教 2007: Fukuoka University, 薬学部, 助教 2005 – 2006: 福岡大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47060:Clinical pharmacy-related / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy / Applied pharmacology Except Principal Investigator Medical pharmacy / Medium-sized Section 48:Biomedical structure and function and related fields / Medium-sized Section 38:Agricultural chemistry and related fields / Basic Section 55060:Emergency medicine-related / Basic Section 48030:Pharmacology-related / General pharmacology / Applied pharmacology
Keywords	Principal Investigator 脳ペリサイト / ペリサイト / 血液脳関門 / 頭部外傷 / ミクログリア / 肥満 / αシヌクレイン / 加齢 / alpha-synuclein / パーキンソン病 … More / PDGFR / PDGFRβ / グルタミン酸 / 神経易興奮性 / アストロサイト / てんかん / 脳内炎症 / 肥満糖尿病 / PDGFRｂ / PDGFRb / 末梢慢性炎症 / トロンビン / TNF-alpha / 肥満症 / シクロフィリンＡ / 視床下部神経 / 脂質ラフト / メチルグリオキサール / 糖尿病 / シクロフィリンA / インスリン抵抗性 / GT1-7 / 脳インスリン抵抗性 / cyclophilin A / MMP-9 / 神経生物学 / 脳微小循環 / 脳微小血管 / 脳血管内皮細胞 / blood brain-barrier / oncostatin M / adrenomedullin … More Except Principal Investigator 血液脳関門 / 脳ペリサイト / パーキンソン病 / αシヌクレイン / オートファジー / 炎症性サイトカイン / サイトカイン / P-glycoprotein / 脳血管内皮細胞 / 時間治療 / iPS細胞 / 時間薬理学 / 経鼻投与 / ヒトiPS細胞 / ペプチド配列 / 質量分析 / 腸炎症 / ペプチドミクス / クレアチン / アポトーシス / CD13 / PDGFRβ / ペリサイト / 急性脳症 / Toll様受容体 / P糖タンパク質 / 炎症性メディエーター / 炎症性腸疾患 / 6-hydroxydopamine / 神経細胞 / ドパミン神経細胞 / ドパミン神経 / 薬剤中枢性副作用 / ケモカイン / Serum amyloid A / 慢性閉塞性肺疾患 / serum amyloid A / タイトジャンクション / ニコチン性アセチルコリン受容体 / 中枢性有害作用 / バレニクリン / Tight Junction / Acute Liver Failure / Cyclosporine A / PAI-1 / Oncostatin M / TNF-α / Blood-Brain Barrier / オーダーメイド医療 / データーマイニング / 中枢性副作用 / RANTES / バイオマーカー / Aβ / TGF-β / pericyte / blood brain barrier / RAGE / AGE / 中枢毒性 / 神経変性疾患 / 炎症 / 糖尿病 / 後期糖化反応生成物 Less

パーキンソン病を誘発する腸炎症疾患：腸-脳連関の鍵となる脳ペリサイト病変化の解明Principal Investigator
- Principal Investigator
  
  高田芙友子
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
A novel peptidomics method to reflect gut intestinal diseases
- Principal Investigator
  
  田中充
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Kyushu University
Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes
- Principal Investigator
  
  道具伸也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Fukuoka University
Novel Therapeutic Strategies through Pericyte Modulation and Apoptosis Prevention in Acute Encephalopathy
- Principal Investigator
  
  山中岳
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Tokyo Medical University
Role of pericytes in alpha-synuclein accumulation in traumatic brain injury mouse modelPrincipal Investigator
- Principal Investigator
  
  Takata Fuyuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
Involvement of activated brain pericytes induced by inflammatory bowel disease in the increased aggregation of alpha-synuclein in the brain.
- Principal Investigator
  
  DOHGU Shinya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
The role of pericytes in the development of epileptogenesis after traumatic brain injuryPrincipal Investigator
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fukuoka University
The brain pericytes-induced blood-brain barrier dysfunction and the central adverse effects in the chronic obstructive pulmonary disease
- Principal Investigator
  
  Kataoka Yasufumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fukuoka University
Involvement of brain pericytes in alpha-synuclein-induced dysfunction of the blood-brain barrier and dopaminergic neurons
- Principal Investigator
  
  DOHGU Shinya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Fukuoka University
A key role of the brain pericytes in the induction and development of brain inflammation under the pathophysiological conditions of obesity-associated diabetes.Principal Investigator
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Fukuoka University
Adverse effects of varenicline on the neurovascular unit
- Principal Investigator
  
  Kataoka Yasufumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fukuoka University
Involvement of pericytes-derived cyclophilin A in the development of insulin resistanse in the brainPrincipal Investigator
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Fukuoka University
Identification of predictive biomarkers for pathological alterations of BBBfunctions.
- Principal Investigator
  
  SHUTO Hideki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fukuoka University
Involvement of brain pericytes in the development of obesityPrincipal Investigator
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Fukuoka University
高脂血症の血液脳関門病態化における脳ペリサイトの役割Principal Investigator
- Principal Investigator
  
  高田芙友子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
後期糖化反応生成物特異的受容体を介した血液脳関門病態の解明
- Principal Investigator
  
  SHUTO Hideki, DOHGU Shinya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University

[Journal Article] Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction2021
- Author(s)
  Fuyuko Takata, Shinsuke Nakagawa, Junichi Matsumoto, Shinya Dohgu
- Journal Title
  
  Frontiers in Cellular Neuroscience.
  
  Volume: 15 Pages: 661838-661838
- DOI
  10.3389/fncel.2021.661838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07338, KAKENHI-PROJECT-20K09394, KAKENHI-PROJECT-21K06703
[Journal Article] Reactive pericytes in early phase are involved in glial activation and late-onset hypersusceptibility to pilocarpine-induced seizures in traumatic brain injury model mice2021
- Author(s)
  Sakai K, Takata F, Yamanaka G, Yasunaga M, Hashiguchi K, Tominaga K, Itoh K, Kataoka Y, Yamauchi A, Dohgu S.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 145 Issue: 1 Pages: 155-165
- DOI
  10.1016/j.jphs.2020.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06712
[Journal Article] Monomeric α-synuclein induces blood-brain barrier dysfunction through activated brain pericytes releasing inflammatory mediators in vitro.2019
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Kimura I, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvasc Res.
  
  Volume: 124 Pages: 61-66
- DOI
  10.1016/j.mvr.2019.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08566
[Journal Article] Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson’s disease2019
- Author(s)
  Nakashima Akio、Yamauchi Atsushi、Matsumoto Junichi、Dohgu Shinya、Takata Fuyuko、Koga Mitsuhisa、Fukae Jiro、Tsuboi Yoshio、Kataoka Yasufumi
- Journal Title
  
  Behavioural Pharmacology
  
  Volume: 30 Issue: 1 Pages: 89-94
- DOI
  10.1097/fbp.0000000000000413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08429
[Journal Article] Activation of the α7 nicotinic acetylcholine receptor upregulates blood-brain barrier function through increased claudin-5 and occludin expression in rat brain endothelial cells2019
- Author(s)
  Kimura Ikuya、Dohgu Shinya、Takata Fuyuko、Matsumoto Junichi、Kawahara Yohei、Nishihira Megumi、Sakada Shohei、Saisho Takuya、Yamauchi Atsushi、Kataoka Yasufumi
- Journal Title
  
  Neuroscience Letters
  
  Volume: 694 Pages: 9-13
- DOI
  10.1016/j.neulet.2018.11.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08429
[Journal Article] Oncostatin M-induced blood-brain barrier impairment is due to prolonged activation of STAT3 signaling in vitro2018
- Author(s)
  Takata Fuyuko、Dohgu Shinya、Matsumoto Junichi、Machida Takashi、Sakaguchi Shinya、Kimura Ikuya、Yamauchi Atsushi、Kataoka Yasufumi
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: 119 Issue: 11 Pages: 9055-9063
- DOI
  10.1002/jcb.27162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08429
[Journal Article] TNF-alpha-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IkappaB-NFkappaB and JAK-STAT3 pathways.2018
- Author(s)
  Matsumoto J, Dohgu S, Takata F, Machida T, Hatip FFB, Hatip-Al-Khatib I, Yamauchi A, Kataoka Y.
- Journal Title
  
  Brain Research
  
  Volume: 1692 Pages: 34-44
- DOI
  10.1016/j.brainres.2018.04.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429, KAKENHI-PROJECT-26460113
[Journal Article] Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat model.2017
- Author(s)
  Machida T, Takata F, Matsumoto J, Miyamura T, Hirata R, Kimura I, Kataoka Y, Dohgu S, Yamauchi A.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 5 Pages: e0177447-e0177447
- DOI
  10.1371/journal.pone.0177447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08429, KAKENHI-PROJECT-26460113
[Journal Article] Role of thrombin-PAR1-PKCθ/δ axis in brain pericytes in thrombin-induced MMP-9 production and blood-brain barrier dysfunction in vitro.2017
- Author(s)
  Machida T, Dohgu S, Takata F, Matsumoto J, Kimura I, Koga M, Nakamoto K, Yamauchi A, Kataoka Y.
- Journal Title
  
  Neuroscience.
  
  Volume: 350 Pages: 146-157
- DOI
  10.1016/j.neuroscience.2017.03.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460113
[Journal Article] Role of thrombin-PAR1-PKCθ/δ axis in brain pericytes in thrombin-induced MMP-9 production and blood-brain barrier dysfunction in vitro.2017
- Author(s)
  Machida T, Dohgu S, Takata F, Matsumoto J, Kimura I, Koga M, Nakamoto K, Yamauchi A, Kataoka Y.
- Journal Title
  
  Neuroscience
  
  Volume: 350 Pages: 146-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08429
[Journal Article] Brain pericytes are the most thrombin-sensitive matrix metalloproteinase-9-releasing cell type constituting the blood-brain barrier in vitro.2015
- Author(s)
  3.Machida T, Takata F, Matsumoto J, Takenoshita H, Kimura I, Yamauchi A, Dohgu S, Kataoka Y
- Journal Title
  
  Neurosci Lett.
  
  Volume: 599 Pages: 109-114
- DOI
  10.1016/j.neulet.2015.05.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460113, KAKENHI-PROJECT-25460236, KAKENHI-PROJECT-26860177
[Journal Article] Brain pericyte-derived soluble factors enhance insulin sensitivity in GT1-7 hypothalamic neurons.2015
- Author(s)
  Takahashi H, Takata F, Matsumoto J, Machida T, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 457(4) Issue: 4 Pages: 532-7
- DOI
  10.1016/j.bbrc.2015.01.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460236, KAKENHI-PROJECT-26460113
[Journal Article] Brain pericytes regulate the blood-brain barrier function2015
- Author(s)
  Dohgu S, Takata F, Kataoka Y
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 146 Issue: 1 Pages: 63-65
- DOI
  10.1254/fpj.146.63
- NAID
  130005087187
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-25460236, KAKENHI-PROJECT-26860177
[Journal Article] Elevated permeability of the blood-brain barrier in mice intratracheally2015
- Author(s)
  Takata F, Tominaga K, Koga M, Dohgu S, Futagami K, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 129 Issue: 1 Pages: 78-81
- DOI
  10.1016/j.jphs.2015.08.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18948, KAKENHI-PROJECT-25460236
[Journal Article] Tumor necrosis factor-α-stimulated brain pericytes possess a unique cytokine and chemokine release profile and enhance microglial activation.2014
- Author(s)
  Matsumoto J, Takata F, Machida T, Takahashi H, Soejima Y, Funakoshi M, Futagami K, Yamauchi A, Dohgu S, Kataoka Y
- Journal Title
  
  Neurosci Lett.
  
  Volume: 578 Pages: 133-8
- DOI
  10.1016/j.neulet.2014.06.052
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460236, KAKENHI-PROJECT-26460113
[Journal Article] In vitro blood-brain barrier models using brain capillary endothelial cells isolated from neonatal and adult rats retain age-related barrier properties.2013
- Author(s)
  Takata, F
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: 55166-55166
- DOI
  10.1371/journal.pone.0055166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240034, KAKENHI-PROJECT-21700422, KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790287
[Journal Article] Paracellular barrier and tight junction protein expression in the immortalized brain endothelial cell lines bEND.3, bEND.5 and mouse brain endothelial cell 4.2013
- Author(s)
  Watanabe T, Dohgu S, Takata F, Nishioku T, Nakashima A, Futagami K, Yamauchi A, Kataoka Y.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 36(3) Pages: 492-495
- NAID
  130003382085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790113
[Journal Article] Metformin induces up-regulation of blood-brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells.2013
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Kaneshima S, Matsuo M, Sakaguchi S, Takeshige Y, Yamauchi A, Kataoka Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 19; 433(4) Issue: 4 Pages: 586-590
- DOI
  10.1016/j.bbrc.2013.03.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-25460236
[Journal Article] Paracellular barrier and tight junction protein expression in theimmortalized brain endothelial cell lines bEND.3, bEND.5 and mouse brain2013
- Author(s)
  Watanabe T, Dohgu S, Takata F, Nishioku T, Nakashima A, Futagami K, YamauchiA, Kataoka Y.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 36(3) Pages: 492-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460236
[Journal Article] Paracellular barrier and tight junction protein expression in the immortalized brain endothelial cell lines bEND.3, bEND.5 and mouse brain endothelial cell 42013
- Author(s)
  Watanabe T, Dohgu S, Takata F, Nishioku T, Nakashima A, Futagami K, Yamauchi A, Kataoka Y
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 36(3) Pages: 492-5
- NAID
  130003382085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790113
[Journal Article] Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells.2012
- Author(s)
  Matsumoto J, Dohgu S, Takata F, Nishioku T, Sumi N, Machida T, Takahashi H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 524(1) Issue: 1 Pages: 45-8
- DOI
  10.1016/j.neulet.2012.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790311
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci.
  
  Volume: 88(11-12) Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci.
  
  Volume: 88(11-12) Issue: 11-12 Pages: 529-34
- DOI
  10.1016/j.lfs.2011.01.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci. 88(11-12)
  
  Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro2011
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Takahashi H, Machida T, Wakigawa T, Harada E, Miyaji H, Koga M, Nishioku T, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Neuroinflammation.
  
  Volume: 8 Issue: 1 Pages: 106-106
- DOI
  10.1186/1742-2094-8-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790311
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M, Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvasc Res.
  
  Volume: 81(1) Pages: 103-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M, Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvasc Res. 81(1)
  
  Pages: 103-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Disruption of the blood-brain barrier in collagen-induced arthritic mice.2010
- Author(s)
  Nishioku T, Yamauchi A, Takata F, Watanabe T, Furusho K, Shuto H, Dohgu S, Kataoka Y.
- Journal Title
  
  Neurosci Lett. 482(3)
  
  Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function.2010
- Author(s)
  Dohgu S, Sumi N, Nishioku T, Takata F, Watanabe T, Naito M, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 644(1-3) Pages: 5-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia.2010
- Author(s)
  Sumi N, Nishioku T, Takata F, Matsumoto J, Watanabe T, Shuto H, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Cell Mot Neurobiol. 30(2)
  
  Pages: 247-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Disruption of the blood-brain barrier in collagen-induced arthritic mice2010
- Author(s)
  Nishioku T, Yamauchi A, Takata F, Watanabe T, Furusho K, Shuto H, Dohgu S, Kataoka Y
- Journal Title
  
  Neurosci Lett
  
  Volume: 482(3) Issue: 3 Pages: 208-11
- DOI
  10.1016/j.neulet.2010.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255
[Journal Article] Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells2010
- Author(s)
  Nishioku T, Matsumoto J, Dohgu S, Sumi N, Miyao K, Takata F, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Pharmacol Sci. 112(2)
  
  Pages: 251-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Disruption of the blood-brain barrier in collagen-induced arthritic mice.2010
- Author(s)
  Nishioku T, Yamauchi A, Takata F, Watanabe T, Furusho K, Shuto H, Dohgu S, Kataoka Y.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 482(3) Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163
[Journal Article] Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia2010
- Author(s)
  Sumi N, Nishioku T, Takata F, Matsumoto J, Watanabe T, Shuto H, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol. 30(2)
  
  Pages: 247-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function.2010
- Author(s)
  Dohgu S, Sumi N, Nishioku T, Takata F, Watanabe T, Naito M, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Eur J Pharmacol. 644(1-3)
  
  Pages: 5-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function.2010
- Author(s)
  Dohgu S, Sumi N, Nishioku T, Takata F, Watanabe T, Naito M, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 644(1-3) Pages: 5-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163
[Journal Article] Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediatedup-regulation of endothelial barrier function.2010
- Author(s)
  Dohgu S, Sumi N, Nishioku T, Takata F, Watanabe T, Naito M, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 644(1-3) Issue: 1-3 Pages: 5-9
- DOI
  10.1016/j.ejphar.2010.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255
[Journal Article] Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells.2010
- Author(s)
  Nishioku T, Matsumoto J, Dohgu S, Sumi N, Miyao K, Takata F, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Pharmacol Sci. 112(2)
  
  Pages: 251-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Disruption of the blood-brain barrier in collagen-induced arthritic mice.2010
- Author(s)
  Nishioku T, Yamauchi A, Takata F, Watanabe T, Furusho K, Shuto H, Dohgu S, Kataoka Y.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 482(3) Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice2009
- Author(s)
  Nishioku T, Dohgu S, Takata F, Eto T, Ishikawa N, Kodama KB, Nakagawa S, Yamauchi A, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol. 29(3)
  
  Pages: 309-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice.2009
- Author(s)
  Nishioku T, Dohgu S, Takata F, Eto T, Ishikawa N, Kodama KB, Nakagawa S, Yamauchi A, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol. 29(3)
  
  Pages: 309-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Inhibition of transforming growth factor-β production in brain pericytes contributes to cyclosporine A-induced dysfunction of the blood-brain barrier2007
- Author(s)
  Takata F, et al.
- Journal Title
  
  Cell. Mol. Neurobiol. (in press)
- Data Source
  KAKENHI-PROJECT-17659160
[Journal Article] Protective action of indapamide, a thiazide-like diuretic, on ischemia-induced injury and barrier dysfunction in mouse brain microvascular endothelial cells.2007
- Author(s)
  Nishioku T, Takata F, Yamauchi A, Sumi N, Yamamoto I, Fujino A, Naito M, Tsuruo T, Shuto H, Kataoka Y.
- Journal Title
  
  J.Pharmacol.Sci. 103(3)
  
  Pages: 323-327
- NAID
  10024313190
- Data Source
  KAKENHI-PROJECT-18890227
[Journal Article] Protective action of indapamide,a thiazide-like diuretic,on ischemia-induced injury and barrier dysfunction in mouse brain micro vascular endothelial cells2007
- Author(s)
  Nishioku T, Takata F, Yamauchi A, Sumi N, Yamamoto I, Fujino A, Naito M, Tsuruo T, Shuto H, Kataokai Y
- Journal Title
  
  J Pharmacol Sci 103(3)
  
  Pages: 323-327
- NAID
  10024313190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890227
[Journal Article] Inhibition of transforming growth factor-beta production in brain pericytes contributes to cyclosporin A-induced dysfunction of the blood-brain barrier2007
- Author(s)
  Takata F, Dohgu S, Yamauchi A, Sumi N, Nakagawa S, Naito M, Tsuruo T, Shuto H, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol 27(3)
  
  Pages: 317-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890227
[Journal Article] Adverse effect of cyclosporin A on barrier functions of cerebral microvascular endothelial cells after hypoxia-reoxygenation damage in vitro2007
- Author(s)
  Dohgu S, Nishioku T, Sumi N, Takata, F Nakagawa S, Naito M, Tsuruo T, Yamauchi A, Shuto H, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol 27(7)
  
  Pages: 889-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890227
[Journal Article] Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production.2005
- Author(s)
  Dohgu S, Takata F, Yamauchi A, Nakagawa S, Egawa T, Naito M, Tsuruo T, Sawada Y, Niwa M, Kataoka Y
- Journal Title
  
  Brain reserch 1038・2
  
  Pages: 208-215
- Data Source
  KAKENHI-PROJECT-17659160
[Journal Article] Inhibition of Transforming Growth Factor-beta Production in Brain Pericytes Contributes to Cyclosporin A-Induced Dysfunction of the Blood-Brain Barrier.
- Author(s)
  Takata F, Dohgu S, Yamauchi A, Sumi N, Nakagawa S, Naito M, Tsuruo T, Shuto H, Kataka Y.
- Journal Title
  
  Cell.Mol.Neurobiol. (In press)
- Data Source
  KAKENHI-PROJECT-18890227
[Patent] 血液脳関門障害症候群治療薬2011
- Inventor(s)
  高田芙友子、道具伸也、片岡泰文、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-12-12
- Overseas
- Data Source
  KAKENHI-PROJECT-23790113
[Patent] 血液脳関門障害症候群治療薬2011
- Inventor(s)
  高田芙友子、道具伸也、片岡泰文、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Filing Date
  2011
- Overseas
- Data Source
  KAKENHI-PROJECT-23790113
[Patent] 血液脳関門障害症候群治療薬2010
- Inventor(s)
  高田芙友子、片岡泰文、道具伸也、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Number
  2010-277027
- Filing Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21790102
[Patent] 血液脳関門障害症候群治療薬2010
- Inventor(s)
  高田芙友子、道具伸也、片岡泰文、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Number
  2010-277027
- Filing Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] α-Synucleinクリアランス能を有するヒトiPS細胞由来脳ペリサイトの作製2024
- Author(s)
  横谷みき、田中泰圭、高田芙友子、松本純一、岩尾卓朗、佐野和憲、道具伸也
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] パーキンソン病の病態進展における血液脳関門の関与2023
- Author(s)
  道具伸也、高田芙友子、岩尾卓朗、田中泰圭、横谷みき、佐野和憲
- Organizer
  第66回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 脳ペリサイトによるα-シヌクレイン分解機構2023
- Author(s)
  横谷みき、高田芙友子、松本純一、岩尾卓朗、安永美保、佐野和憲、道具伸也
- Organizer
  第13回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Aging-induced changes in mRNA expression of dopaminergic neuronrelated genes in C57BL/6 mouse brain2022
- Author(s)
  Eren Tashiro, Fuyuko Takata, Takuro Iwao, Yuko Fukunaga, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06813
[Presentation] Cyclophillin A is involved in the uptake of oligomericα-synuclein by brain pericytes2022
- Author(s)
  Miki Yokoya, Fuyuko Takata, Takuro Iwao, Junichi Matsumoto, Miho Yasunaga, Hisataka Aridome, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] Involvement of P-glycoprotein in α-synuclein aggregate-induced inflammatory mediator release by brain pericytes2022
- Author(s)
  Shinya Dohgu, Miki Yokoya, Minami Akizuki, Atsushi Kobayashi, Fuyuko Takata, Takuro 　　　　　　Iwao, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Kazunori Sano
- Organizer
  4th Mini-Symposium on the Blood-Brain Barrier from Basic to Clinical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] Decreased brain uptake of cyclosporin A and tacrolimus in the inflammatory bowel disease mice.2022
- Author(s)
  Fuyuko Takata, Yuko Yoshinaga, Takuro Iwao, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] Involvement of P-glycoprotein in α-Synuclein aggregate-induced inflammatory mediator release by brain pericytes2022
- Author(s)
  Shinya Dohgu, Miki Yokoya, Minami Akizuki, Atsushi Kobayashi, Fuyuko Takata, Takuro Iwao, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Kazunori Sano
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] Brain transport of the immunosuppressive agents across BBB is decreased in the inflammatory bowel disease mice.2021
- Author(s)
  Fuyuko Takata, Yuko Yoshinaga, Takuro Iwao, Miho Yasunaga, Shinya Dohgu
- Organizer
  The 23rd international symposium on Signal Transduction at the Blood-Brain Barriers
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] Enhanced glutamate uptake in the astrocytes cocultured with brain pericytes.2021
- Author(s)
  Fuyuko Takata, Kenta Sakai, Takuro Iwao, Atsushi Yamauchi, Yasufumi Kataoka, Shinya Dohgu
- Organizer
  3rd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] 2)Toll様受容体を介した脳ペリサイト特異的なαシヌクレインによる炎症性メディエーター産生2020
- Author(s)
  道具伸也、秋月美波、小林篤史、盛田隼矢、高田芙友子、松本純一、岩尾卓朗、山内淳史、佐野和憲、片岡泰文
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 1)脳ペリサイトによるα－シヌクレインオリゴマーの細胞内取り込み機構2020
- Author(s)
  横谷みき、道具伸也、高田芙友子、松本純一、岩尾卓朗、山内淳史、佐野和憲、片岡泰文
- Organizer
  日本薬学会第140回年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 5)Involvement of Toll-like receptors in brain pericyte specific production of inflammatory mediators induced by α-synuclein2020
- Author(s)
  Shinya Dohgu, Minami Akizuki, Atsushi Kobayashi, Shunya Morita, Fuyuko Takata, Junichi Matsumoto, Takuro Iwao, Atsushi Yamauchi, Kazunori Sano, Yasufumi Kataoka
- Organizer
  2nd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 6.Activated pericytes in the early stage after traumatic brain injury is a key trigger of the progression of microglial activation and neuronal hyperexcitability in the stage in mice.2020
- Author(s)
  Fuyuko Takata
- Organizer
  2nd Mini-symposium on the blood-brain barrier from basic to clinical research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] 脳ペリサイトにおけるαシヌクレインの取り込みおよび分解機構2019
- Author(s)
  道具伸也、矢野瑞紀、横谷みき、高田芙友子、松本純一、木村郁哉、山内淳史、片岡泰文
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K08566
[Presentation] 頭部外傷後の脳ペリサイトPDGFRβシグナル阻害は、pilocarpineけいれん発作の感受性を減弱させる2019
- Author(s)
  坂井研太、高田芙友子、冨永一樹、橋口夏奈、安永美保、山内淳史、道具伸也、片岡泰文
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] 12.PDGFRβ signal inhibition in brain pericytes suppresses glial activation and increased seizure susceptibility to pilocarpine in mice with traumatic brain injury.2019
- Author(s)
  Kenta Sakai, Fuyuko Takata, Yoshie Tanaka, Yume Sezaki, Kazuki Tominaga, Kana Hashiguchi, Miho Yasunaga, Atsushi Yamauchi, Shinya Dohgu, Yasufumi Kataoka.
- Organizer
  13th International Conference at Cerebral Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] ピロカルピン誘発けいれん感受性テストを用いた頭部外傷後のてんかん原性評価2019
- Author(s)
  高田芙友子、坂井研太、道具伸也、瀬崎由愛、田中淑恵、山中岳、河島尚志、伊藤康一、山内淳史、片岡泰文
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] 10.Increased PDGFRβ expression of the pericytes in the early stage after traumatic brain injury is a major cause of the subsequent activation of microglia and hypersusceptibility to pilocarpine-induced seizure in mice.2019
- Author(s)
  Fuyuko Takata, Kenta Sakai, Atsushi Yamauchi, Shinya Dohgu, Yasufumi Kataoka
- Organizer
  NEURO 2019 (Late Breaking)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] 脳ペリサイトによるα－シヌクレインの細胞内取り込み機構2018
- Author(s)
  矢野瑞紀、道具伸也、横谷みき、高田芙友子、松本純一、木村郁哉、山内淳史、片岡泰文
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] α7 nAChR 作動薬によるTNF-α誘発性血液脳関門機能障害の修復作用機序2018
- Author(s)
  西平恵、道具伸也、高田芙友子、木村郁哉、山内淳史、片岡泰文
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] Dysregulation of the CNS supporting vascular and glial cells induces the late posttraumatic epilepsy in mice with mild traumatic brain injury.2018
- Author(s)
  Kenta Sakai, Fuyuko Takata, Shinya Dohgu, Mitsuhisa Koga, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  18th World Congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] In response to monomeric α-synuclein, brain pericytes release inflammatory cytokines to impair brain endothelial barrier2018
- Author(s)
  Shinya Dohgu, Fuyuko Takata, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  18th World congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] In response to monomeric α-synuclein, brain pericytes release inflammatory cytokines to impair brain endothelial barrier2018
- Author(s)
  Shinya Dohgu, Fuyuko Takata, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka.
- Organizer
  18th World congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08566
[Presentation] 血液脳関門への加熱式タバコ抽出物の影響の検討2018
- Author(s)
  木村郁哉、道具伸也、高田芙友子、松本純一、力武真衣、縄田理永、江口夏海、山内淳史、片岡泰文
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] 脳ペリサイトによるα－シヌクレインの細胞内取り込み機構2018
- Author(s)
  矢野瑞紀、道具伸也、横谷みき、高田芙友子、松本純一、木村郁哉、山内淳史、片岡泰文
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-16K08566
[Presentation] Effect of the heat-not-burn tobacco-extracted substances on the brain endothelial barrier function in vitro2018
- Author(s)
  Ikuya Kimura, Shinya Dohgu, Fuyuko Takata, Junichi Matsumoto, Mai Rikitake, Atsushi Yamauchi, Yasufumi Kataoka.
- Organizer
  18th World congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] 脳血管内皮細胞－ペリサイト細胞間PDGF-BB/PDGFRβシグナル減弱が低酸素・低グルコース誘発性血液脳関門機能障害に関与する2018
- Author(s)
  木村郁哉、道具伸也、高田芙友子、松本純一、吉田若菜、吉松あや、田中春花、山内淳史、片岡泰文
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] Dysregulation of the CNS supporting vascular and glial cells induces the late posttraumatic epilepsy in mice with mild traumatic brain injury.2018
- Author(s)
  Kenta Sakai, Fuyuko Takata, Shinya Dohgu, Mitsuhisa Koga, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka.
- Organizer
  18th World Congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] Oncostatin M downregulates the brain endothelial barrier integrity through long-lasting activation of JAK/STAT3 pathway.2018
- Author(s)
  Fuyuko Takata, Shinya Dohgu, Junichi Matsumoto, Takashi Machida, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  18th World Congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] 脳ペリサイトは6-OHDA誘発性ドパミン神経細胞傷害を防御する2017
- Author(s)
  有留尚孝、道具伸也、牛尾誠幸、藤田侑里、木村郁哉、高田芙友子、片岡泰文、山内淳史
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール、長崎新聞文化ホール　アストピア
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08566
[Presentation] An interaction between thrombin and pericytes mediates the blood-brain barrier dysfunction in obesity-associated diabetes2017
- Author(s)
  Fuyuko Takata, Shinya Dohgu, Takashi Machida, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  12th international conference on cerebral vascular biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] α-Synuclein-reactive pericytes contribute to the blood-brain barrier dysfunction through the release of inflammatory cytokines in vitro.2017
- Author(s)
  Shinya Dohgu, Fuyuko Takata, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  Cerebral Vascular Biology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08566
[Presentation] 脳血管内皮細胞－ペリサイト間PDGF-BB/PDGFRbシグナル減弱が低酸素・低グルコース誘発性血液脳関門障害に関与する2017
- Author(s)
  木村郁哉、道具伸也、高田芙友子、松本純一、吉田若菜、吉松あや、田中春花、山内淳史、片岡泰文
- Organizer
  第70回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] Lowered PDGF-BB/PDGFRb signaling between brain endothelial cells and pericyte contributes to the blood-brain barrier disruption induced by oxygen-glucose deprivation.2017
- Author(s)
  Ikuya Kimura, Shinya Dohgu, Fuyuko Takata, Junichi Matsumoto, Wakana Yoshida, Aya Yoshimatsu, Haruka Tanaka, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  Cerebral Vascular Biology 2017.
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] 脳ペリサイトは6-OHDA誘発性ドパミン神経細胞傷害を防御する2017
- Author(s)
  有留尚孝、道具伸也、牛尾誠幸、藤田侑里、木村郁哉、高田芙友子、片岡泰文、山内淳史
- Organizer
  七隈アルツハイマー病・パーキンソン病研究会
- Place of Presentation
  BiVi福岡　6F 会議室1-3
- Year and Date
  2017-04-08
- Data Source
  KAKENHI-PROJECT-16K08566
[Presentation] TNF-a-stimulated brain pericytes activate microglia to induce inflammation at the neurovascular unit2016
- Author(s)
  Fuyuko Takata-Tsuji, Shinya Dohgu, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  19 th international symposium on signal transduction at the Blood-Brain Barriers
- Place of Presentation
  Copenhagen Denmark
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] 脳ペリサイトのPAR1-PKCδ/θシグナルはトロンビン誘発性MMP-9産生及び血液脳関門障害に関与する2016
- Author(s)
  道具伸也, 町田　崇, 高田芙友子, 木村郁哉, 松本純一, 山内淳史, 片岡泰文
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 脳ペリサイトのPAR1-PKCδ/θシグナルはトロンビン誘発性MMP-9産生および血液脳関門障害に関与する2016
- Author(s)
  道具伸也、町田崇、高田芙友子、木村郁也、松本純一、山内淳史、片岡泰文
- Organizer
  第８９回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] The role of pericytes in the TNF-a-mediated brain inflammation2016
- Author(s)
  Fuyuko Takata-Tsuji, Shinya Dohgu, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  Joint Franco-Italian-Swiss multinational meeting on blood-brain interfaces
- Place of Presentation
  Lyon France
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] α7 ニコチン性アセチルコリン受容体によるBBB機能の亢進2016
- Author(s)
  木村郁哉, 道具伸也, 高田芙友子, 松本純一, 川原庸平, 山内淳史, 片岡泰文
- Organizer
  第136回日本薬学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] TNF-a-stimulated brain pericytes activate microglia to induce inflammation at the neurovascular unit2016
- Author(s)
  Fuyuko Takata-Tsuji, Shinya Dohgu, Junichi Matsumoto, Ikuya Kimura, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  19 th international Symposium on Signal Transduction at the Blood-Brain Barriers
- Place of Presentation
  Copenhagen Denmark
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08429
[Presentation] IL-1βおよびTNF-αによる血液脳関門機能障害における細胞内情報伝達機構2015
- Author(s)
  古瀬由奈, 道具伸也, 高田芙友子, 松本純一, 木村郁哉, 吉田　愛, 有留尚孝, 岩尾悠可, 納富　夕, 山内淳史, 片岡泰文
- Organizer
  第68回日本薬理学会西南部会
- Place of Presentation
  下関
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 脳ペリサイトはTNF-αに応答してグリア細胞より多量のIL-6 を遊離する。-脳ペリサイトのIL-6産生における細胞内シグナル経路の役割-2015
- Author(s)
  松本純一、道具伸也、高田芙友子、町田崇、二神幸次郎、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] 脳ペリサイトはTNF-aに応答してミクログリアを活性化する2015
- Author(s)
  高田芙友子、松本純一、道具伸也、町田崇、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] 糖尿病によるBBB 機能不全におけるトロンﾋﾞン反応性脳ペリサイトの役割2015
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、平田亮介、宮村知幸、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] 脳ペリサイトにおけるニコチン性アセチルコリン受容体によるTNF-a誘発性MMP-9産生の修飾2014
- Author(s)
  木村郁哉、道具伸也、高田芙友子、松本純一、町田崇、山内淳史、片岡泰文
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] AMPK活性化を介したメトホルミンの血液脳関門機能強化作用2014
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、山内淳史、片岡泰文
- Organizer
  第3回日本くすりと糖尿病学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] TNF-αに対する脳ペリサイト応答を介するミクログリア活性化機構2014
- Author(s)
  船越美帆、松本純一、高田芙友子、道具伸也、町田崇、穴井佑佳、二神幸次郎、山内淳史、片岡泰文
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] TNF-α刺激により脳ペリサイトはミクログリアを活性化する2014
- Author(s)
  高田芙友子、松本純一、道具伸也、町田崇、山内淳史、片岡泰文
- Organizer
  第16回応用薬理シンポジウム
- Place of Presentation
  宮城
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-26460113
[Presentation] 脳ペリサイト由来液性因子による血液脳関門障害2013
- Author(s)
  道具伸也、高田芙友子、松本純一、町田崇、高橋弘之、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Alpha7 nicotinic acetylcholine receptor mediates MMP-9 release from brain pericytes2013
- Author(s)
  木村郁哉、道具伸也、高田芙友子、松本純一、町田崇、則之宏志、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイト由来液性因子による血液脳関門障害2013
- Author(s)
  道具伸也、高田芙友子、松本純一、町田崇、高橋弘之、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Adenosine stimulates brain pericytes to release matrix metalloproteinase-9 through A3 adenosinereceptor2013
- Author(s)
  庄垣内慎、高田芙友子、松本純一、町田崇、山本唯、相川遥、永田怜美、道具伸也、片岡泰文
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイトの細胞外MMP-9放出におけるP糖タンパク質の関与2013
- Author(s)
  道具伸也、高田芙友子、松本純一、町田崇、古賀夕依、山内淳史、片岡泰文
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  コクヨホール
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 脳ペリサイト由来液性因子による血液脳関門障害2013
- Author(s)
  道具伸也、高田芙友子、松本純一、町田崇、高橋弘之、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] Adenosine stimulates brain pericytes to release matrix metalloproteinase-9 through A3 adenosine receptor2013
- Author(s)
  庄垣内慎、高田芙友子、松本純一、町田崇、山本唯、相川遥、永田怜美、道具伸也、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Brain pericytes contribute to the blood-brain barrier disruption induced by thrombin2013
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、竹之下恭代、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Alpha7 nicotinic acetylcholine receptor mediates MMP-9 release from brain pericytes2013
- Author(s)
  木村郁哉、道具伸也、高田芙友子、松本純一、町田崇、則之宏志、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] メトホルミンによる血液脳関門機能強化2013
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、山内淳史、片岡泰文
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  コクヨホール
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 脳ペリサイトによるTNF-a誘発性サイトカイン/ケモカイン産生とミクログリア活性化亢進2013
- Author(s)
  松本純一、道具伸也、高田芙友子、副島由貴、船越美帆、田中彩加、山内淳史、二神幸次郎、片岡泰文
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] メトホルミンによる血液脳関門機能強化2013
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、山内淳史、片岡泰文
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  コクヨホール
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] In vitro blood-brain barrier models using brain capillary endothelial cells isolated fromneonatal and adult rats retain age-related barrier properties2012
- Author(s)
  松本純一、高田芙友子、道具伸也、町田崇、小泉修一、山内淳史、片岡泰文
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイトはマクロファージの脳実質内浸潤を阻害する2012
- Author(s)
  道具伸也、高田芙友子、松本純一、高橋弘之、町田崇、一木奈津子、関菜摘子、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] In vitro blood-brain barrier models using brain capillary endothelial cells isolated from neonatal and adult rats retain age-related barrier properties2012
- Author(s)
  Junichi Matsumoto, Fuyuko Takata, Shinya Dohgu, Takashi Machida, Schuichi Koizumi , Atsushi Yamauchi and Yasufumi Kataoka
- Organizer
  日本薬物動態学会　第27回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Atorvastatin誘導神経突起伸長における正常型プリオン蛋白質の関与2012
- Author(s)
  渡辺拓也、道具伸也、高田芙友子、町田崇、池松由加、平賀千絵
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本大学薬学部
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイトは血液脳関門構成細胞のなかで最大のTNF-α誘発性MMP-9産生能と細胞遊走能を有する2012
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、高橋弘之、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 乳幼児と成人期の血液脳関門in vitroモデル2012
- Author(s)
  高田芙友子
- Organizer
  第１４回応用薬理シンポジウム
- Place of Presentation
  ベルクラシック甲府
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 乳児期と成人期の血液脳関門invitroモデルシンポジウム5血液脳関門を捉える2012
- Author(s)
  高田芙友子
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  山梨
- Year and Date
  2012-09-04
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイトに特異的なTNF-α誘発性MMP-9産生における活性酸素種およびERK1/2・Aktの遅延的活性化の関与2012
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、高橋弘之、宮地晴樹、園木優唯、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 乳幼児と成人期の血液脳関門in vitroモデル2012
- Author(s)
  高田芙友子
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  ベルクラシック甲府
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 乳児期と成人期の血液脳関門in vitroモデル　シンポジウム5　血液脳関門を捉える2012
- Author(s)
  高田芙友子
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  ベルクラシック甲府
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Atrvastatin誘導神経突起伸長にける正常型プリオン蛋白質の関与2012
- Author(s)
  渡辺拓也、道具伸也、高田芙友子、町田崇、池松由加、平賀千絵、二神幸次郎、山内淳史、片岡泰文
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本大学薬学部
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] インスリンによる視床下部神経細胞のAkt活性化に対する脳ペリサイトの促進的関与2011
- Author(s)
  高橋弘之、道具伸也、高田芙友子、松本純一、渡辺拓也、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 低酸素病態下での脳ペリサイトMMP-9産生における脳血管内皮細胞由来CD39/ENTPDase1の作用2011
- Author(s)
  古野龍也、高田芙友子、松本純一、高橋弘之、南里朋、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 血液脳関門における脳ペリサイト特異的なTNF-a誘発性MMP-9産生・放出機構2011
- Author(s)
  宮地晴樹、道具伸也、高田芙友子松本純一、高橋弘之、園木優唯、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 血液脳関門における脳ペリサイト特異的なTNF-α誘発性MMP-9産生・放出機構2011
- Author(s)
  宮地晴樹、道具伸也、高田芙友子、松本純一、高橋弘之、園木優唯、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 低酸素病態下での脳ペリサイトMMP-9産生における脳血管内皮細胞由来CD39/ENTPDaselの作用2011
- Author(s)
  古野龍也、高田芙友子、松本純一、高橋弘之、南里朋、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] インスリンによる視床下部神経細胞のAkt活性化に対する脳ペリサイトの促進的関与2011
- Author(s)
  高橋弘之、道具伸也、高田芙友子、松本純一、渡辺拓也、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] インスリンによる視床下部神経細胞のAkt活性化に対する脳ペリサイトの促進的関与2011
- Author(s)
  高橋弘之、道具伸也、高田芙友子、松本純一、渡辺拓也、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 脳ペリサイトにおけるJAK/STAT経路を介したIL-6放出機構2011
- Author(s)
  峠沙也香、松本純一、高田芙友子、高橋弘之、川口真奈美、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 血液脳関門における脳ペリサイト特異的なTNF-α誘発性MMP-9産生・放出機構2011
- Author(s)
  宮地晴樹、道具伸也、高田芙友子、松本純一、高橋弘之、園木優唯、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 炎症細胞の脳浸潤における脳ペリサイトの役割2011
- Author(s)
  一木奈津子、道具伸也、高田芙友子、松本純一、高橋弘之、関菜摘子、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 血液脳関門における脳ペリサイト特異的なTNF-a誘発性MMP-9産生・放出機構2011
- Author(s)
  宮地晴樹、道具伸也、高田芙友子、松本純一、高橋弘之、園木優唯、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] インスリンによる視床下部神経細胞のAkt活性化に対する脳ペリサイトの促進的関与2011
- Author(s)
  高橋弘之、道具伸也、高田芙友子松本純一、渡辺拓也、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 低酸素病態下での脳ペリサイトMMP-9産生における脳血管内皮細胞由来CD39/ENTPDase1の作用2011
- Author(s)
  古野龍也、高田芙友子、松本純一、高橋弘之、南里朋、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 低酸素病態下での脳ペリサイトMMP-9産生における脳血管内皮細胞由来CD39小ENTPDase1の作用2011
- Author(s)
  古野龍也、高田芙友子、松本純一、高橋弘之、南里朋、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイトにおけるJAK/STAT経路を介したIL-6放出機構2011
- Author(s)
  峠沙也香、松本純一、高田芙友子高橋弘之、川口真奈美、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] 脳ペリサイトのIL-6放出機構2011
- Author(s)
  松本純一、道具伸也、高田芙友子、堂籠航、川口真奈美、山内淳史、片岡泰文
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  KKRホテル博多
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] Impaired blood brain barrier functions in the pre diabetic mice.2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Takahashi H, Watanabe T, Koga M, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium
- Place of Presentation
  University Hospital Zurich(スイス)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Impaired blood-brain barrier functions in the pre-diabetic mice.2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Takahashi H, Watanabe T, Koga M, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium Zurich
- Place of Presentation
  Switzerland
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] カルシニューリン/NFAT経路を介した脳ペリサイトのMMP-9産生機構2010
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、古野龍也、金嶋修司、渡辺拓也、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] NADPH oxidase-derived reactive oxygen species(ROS)facilitate TNF-alpha-induced up-regulation of MMP-9 production in the brain pericytes through Akt activation.2010
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Furuno T, Ichiki N, Kaneshima S, Miyaji H, Tao S, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium
- Place of Presentation
  University Hospital Zurich(スイス)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] カルシニューリン/NFAT経路を介した脳ペリサイトのMMP-9産生機構2010
- Author(s)
  町田崇、道具伸也、高田芙友子、松木純一、古野龍也、金嶋修司、渡辺拓也、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] Impaired blood-brain barrier functions in the pre-diabetic mice2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Takahashi H, Watanabe T, Koga M, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium
- Place of Presentation
  University Hospital Zurich(スイス)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Impaired blood-brain barrier functions in the pre-diabetic mice.2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Takahashi H, Watanabe T, Koga M, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  Zurich(スイス)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] NADPH oxidase-derived reactive oxygen species (ROS) facilitate TNF-alpha-induced up-regulation of MMP-9 production in the brain pericytes through Akt activation.2010
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Furuno T, Ichiki N, Kaneshima S, Miyaji H, Tao S, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium Zurich
- Place of Presentation
  Switzerland
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] NADPH oxidase-derived reactive oxygen species (ROS) facilitate TNF-alpha-induced up-regulation of MMP-9 production in the brain pericytes through Akt activation.2010
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Furuno T, Ichiki N, Kaneshima S, Miyaji H, Tao S, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  Zurich(スイス)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 肥満および耐糖能異常を呈したマウスにおける血液脳関門機能障害2010
- Author(s)
  高田芙友子、道具伸也、小原昂上、松本純一、西奥剛、山内淳史、首藤英樹、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 肥満および耐糖能異常を呈したマウスにおける血液脳関門機能障害2010
- Author(s)
  高田芙友子、道具伸也、小原昂士、松本純一、西奥剛、山内淳史、首藤英樹、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 脳ペリサイトのMMP-9産生における活性酸素種の役割2010
- Author(s)
  松本光輔、道具伸也、高田芙友子、松本純一、一木奈津子、峠沙也香、宮地晴樹、西奥剛、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 脳ペリサイトのMMP-9産生における活性酸素種の役割2010
- Author(s)
  松本光輔、道具伸也、高田芙友子、松本純一、一木奈津子、峠沙也香、宮地晴樹、西奥剛、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] NADPH oxidase-derived reactive oxygen species (ROS) facilitate TNF-alpha-induced up-regulation of MMP-9 production in the brain pericytes through Akt activation2010
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Furuno T, Ichiki N, Kaneshima S, Miyaji H, Tao S, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-BrainBarrier Symposium
- Place of Presentation
  UniversityHospital Zurich(スイス)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590163
[Presentation] Activated protein C inhibits TNF-α induced MMP-9 production in the brain pericytes.2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Harada E, Matsumoto K, Nishioku T, Yamauchi A, Kataoka Y.
- Organizer
  8^<th> cerebral vascular biology international conference
- Place of Presentation
  Sendai, Japan
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] TNF-α stimulates MMP-9 secretion in the brain pericytes by activating ERK1/2, JNK and PI3 kinase signaling pathway2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Matsumoto J, Harada E, Matsumoto K, Yamauchi A., Kataoka Y.
- Organizer
  12^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  University College London
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] TNF-astimulates MMP-9 secretion in the brain pericytes by activating ERK1/2, JNK and PI3 kinase signaling pathway.2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Matsumoto J, Harada E, Matsumoto K, Yamauchi A, Kataoka Y.
- Organizer
  12^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  University College London, United Kingdam
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] Activated protein C inhibits TNF-α induced MMP-9 production in the brain pericytes2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Harada E, Matsumoto K, Nishioku T, Yamauchi A, Kataoka Y.
- Organizer
  8^<th> cerebral vascular biology international conference
- Place of Presentation
  Sendai Excel Hotel Tokyu
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] メチルグリオキサールは視床下部神経細胞のインスリンシグナルを阻害する
- Author(s)
  道具伸也、高田芙友子、松本純一、町田崇、高木麻衣、吉見幸那、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] AMPK活性化を介したメトホルミンの血液脳関門機能強化作用
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、山内淳史、片岡泰文
- Organizer
  第3回日本くすりと糖尿病学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-11-02 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 脳ペリサイトはTNF-aに応答してミクログリアを活性化する
- Author(s)
  高田芙友子、松本純一、道具伸也、町田崇、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 脳ペリサイトはTNF-αに応答してグリア細胞より多量のIL-6 を遊離する。-脳ペリサイトのIL-6産生における細胞内シグナル経路の役割-
- Author(s)
  松本純一、道具伸也、高田芙友子、町田崇、二神幸次郎、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460236
[Presentation] 糖尿病によるBBB 機能不全におけるトロンビン反応性脳ペリサイトの役割
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、平田亮介、宮村知幸、山内淳史、片岡泰文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460236

1. DOHGU Shinya (60399186)

# of Collaborated Projects: 11 results

# of Collaborated Products: 138 results
2. KATAOKA Yasufumi (70136513)

# of Collaborated Projects: 7 results

# of Collaborated Products: 96 results
3. MATSUMOTO Junichi (10550064)

# of Collaborated Projects: 4 results

# of Collaborated Products: 52 results
4. SHUTO Hideki (60412574)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
5. 岩尾卓朗 (30846374)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. MACHIDA Takashi (30586144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
7. 山内淳史 (90341453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 古賀允久 (60570801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 山中岳 (70349512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 黒澤裕子 (90623108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中充 (70584209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田中泰圭 (50714466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 牛島健太郎 (70448843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takata Fuyuko 高田 芙友子

TAKATA Fuyuko 高田 芙友子

高田 芙友子 タカタ フユコ

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パーキンソン病を誘発する腸炎症疾患：腸-脳連関の鍵となる脳ペリサイト病変化の解明Principal Investigator

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Role of pericytes in alpha-synuclein accumulation in traumatic brain injury mouse modelPrincipal Investigator

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The role of pericytes in the development of epileptogenesis after traumatic brain injuryPrincipal Investigator

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A key role of the brain pericytes in the induction and development of brain inflammation under the pathophysiological conditions of obesity-associated diabetes.Principal Investigator

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Involvement of pericytes-derived cyclophilin A in the development of insulin resistanse in the brainPrincipal Investigator

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Involvement of brain pericytes in the development of obesityPrincipal Investigator

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Takata Fuyuko 高田芙友子

TAKATA Fuyuko 高田芙友子

高田芙友子タカタフユコ