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HAMADA Yoshio  浜田 芳男

… Alternative Names

浜田 芳男  ハマダ ヨシオ

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Researcher Number 70424968
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2602-6917
Affiliation (Current) 2025: 甲南大学, フロンティアサイエンス研究科, 特別研究員
Affiliation (based on the past Project Information) *help 2016 – 2023: 甲南大学, フロンティアサイエンス研究科, 特別研究員
2014 – 2015: 神戸薬科大学, 薬学部, 研究員
2011 – 2013: 神戸学院大学, 薬学部, 研究員
Review Section/Research Field
Principal Investigator
Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Except Principal Investigator
Basic Section 47060:Clinical pharmacy-related / Basic Section 49030:Experimental pathology-related
Keywords
Principal Investigator
アミロイドβ / 酵素阻害剤 / β-セクレターゼ / BACE1 / アルツハイマー病 / BACE1阻害剤 / アミロイドβペプチド / 凝集阻害剤 / セクレターゼ / 有機合成 … More / η-セクレターゼ / Aイーターペプチド / アミロイドベータ / セクレターぜ阻害剤 / セクレターゼ阻害剤 / 凝集祖愛剤 / 創薬 / ドッキング計算 / β‐セクレターゼ / 阻害剤 米国 / ペプチド … More
Except Principal Investigator
皮膚感作性試験 / DPRA法 / 皮膚感作性試験法 / 接着分子 / アルツハイマー病 / 認知症 / 内在化 / 薬物送達系 / 経鼻的頭蓋内送達 / 抗体薬物複合体 Less
  • Research Projects

    (5 results)
  • Research Products

    (73 results)
  • Co-Researchers

    (11 People)
  •  Development of antibody drugs based on internalization of cell membrane proteins

    • Principal Investigator
      Ito Akihiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kindai University
  •  Evaluation method of skin sensitization using chromophore-based solid phase peptide reaction assay in vitro.

    • Principal Investigator
      有海 秀人
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Tokyo University of Science, Yamaguchi
  •  Design of beta- and eta-secretase inhibitors for the treatment of Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      Hamada Yoshio
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Konan University
  •  Design of inhibitors of amyloid beta aggregation and BACE1 for conquering Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      HAMADA Yoshio
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Konan University
      Kobe Pharmaceutical University
  •  Integrated drug discovery study for conquering Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      HAMADA Yoshio
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kobe Pharmaceutical University
      Kobe Gakuin University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

  • [Book] Peptide Synthesis2020

    • Author(s)
      Yoshio Hamada, Zyta M. Ziora
    • Total Pages
      9
    • Publisher
      Springer Nature
    • ISBN
      9781071602270
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Book] Peptide Synthesis2019

    • Author(s)
      Yoshio Hamada
    • Total Pages
      12
    • Publisher
      Intech
    • ISBN
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Book] Kirk‐Othmer Encyclopedia of Chemical Technology2019

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Total Pages
      20
    • Publisher
      John Willy & Sons, Inc.
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Book] Pyridine2018

    • Author(s)
      Yoshio Hamada
    • Total Pages
      18
    • Publisher
      Intech
    • ISBN
      9781789234237
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Book] バイオ医薬品の開発と市場 20192018

    • Author(s)
      浜田芳男
    • Total Pages
      14
    • Publisher
      シーエムシー出版
    • ISBN
      9784781313559
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Book] Quantitative Structure-activity Relationship2017

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Total Pages
      16
    • Publisher
      Intech
    • ISBN
      9789535134091
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Book] DDS先端技術の製剤への応用開発2017

    • Author(s)
      浜田芳男
    • Total Pages
      9
    • Publisher
      技術情報協会
    • ISBN
      9784861046636
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Book] Computational Modeling of Drugs Against Alzheimer’s Disease2017

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Total Pages
      21
    • Publisher
      Springer Nature
    • ISBN
      9781493974030
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Book] Amino Acids, Peptides and Proteins, volume 392015

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Total Pages
      34
    • Publisher
      Royal Society of Chemistry
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Book] Amino Acids, Peptides and Proteins, volume 392015

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Total Pages
      34
    • Publisher
      Royal Society of Chemistry
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Book] 遺伝子医学MOOK21「最新ペプチド合成技術とその創薬研究への応用」2012

    • Author(s)
      浜田芳男、木曽良明
    • Total Pages
      10
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Book] 和光純薬時報 「アルツハイマー病とBACE1阻害剤の設計」2011

    • Author(s)
      浜田芳男、木曽良明
    • Total Pages
      3
    • Publisher
      和光純薬工業株式会社
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Journal Article] De novo design of a nanopore for single-molecule detection that incorporates a β-hairpin peptide2021

    • Author(s)
      Shimizu Keisuke、Mijiddorj Batsaikhan、Usami Masataka、Mizoguchi Ikuro、Yoshida Shuhei、Akayama Shiori、Hamada Yoshio、Ohyama Akifumi、Usui Kenji、Kawamura Izuru、Kawano Ryuji
    • Journal Title

      Nature Nanotechnology

      Volume: - Issue: 1 Pages: 67-75

    • DOI

      10.1038/s41565-021-01008-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H00390, KAKENHI-PROJECT-19H00901, KAKENHI-PROJECT-18K06562, KAKENHI-PROJECT-19K05741
  • [Journal Article] Development of a chromophore-solid phase peptide reaction assay (C-SPRA) for assessing skin sensitization in vitro2020

    • Author(s)
      Miyazaki Hiroshi、Hamada Yoshio、Takaishi Hikaru、Minamino Yuuki、Ikeda Hidefumi、Mekata Hideaki、Takaishi Masayuki、Yamashita Kunihiko、Usui Kenji
    • Journal Title

      The Analyst

      Volume: 145 Issue: 9 Pages: 3211-3216

    • DOI

      10.1039/c9an02514f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06562, KAKENHI-PROJECT-19K05741
  • [Journal Article] Synthesis of peptide-immobilized magnetic beads, and peptide reactivity assay for assessing skin sensitization utilizing chromophore2020

    • Author(s)
      Hiroshi Miyazaki, Hikaru Takaishi, Hidefumi Ikeda, Hideto Ariumi, Yoshio Hamada, Kunihiko Yamashita, Kenji Usui
    • Journal Title

      Processes

      Volume: 8 Issue: 10 Pages: 1-10

    • DOI

      10.3390/pr8101257

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06562, KAKENHI-PROJECT-19K05741
  • [Journal Article] Mass spectrometry-based solid phase peptide reaction assay for detecting allergenicity using an immobilized peptide-conjugating photo-cleavable linker2020

    • Author(s)
      Hiroshi Miyazaki,Yasutaka Samejima, Kazuya Iwata,Yuuki Minamino, Shinya Hikida,Hideto Ariumi, Hidefumi Ikeda, Yoshio Hamada, Kunihiko Yamashita, Kenji Usui
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 21 Pages: 1-10

    • DOI

      10.3390/ijms21218332

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06562, KAKENHI-PROJECT-19K05741
  • [Journal Article] Peptides for Silica Precipitation: Amino Acid Sequences for Directing Mineralization2018

    • Author(s)
      Makoto Ozaki, Shungo Sakashita, Yoshio Hamada, Kenji Usui
    • Journal Title

      Protein & Peptide Letters

      Volume: 25 Issue: 1 Pages: 15-24

    • DOI

      10.2174/0929866525666171214111007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Journal Article] Editorial: Organic-Inorganic Hybrid Materials and Their Applications2018

    • Author(s)
      Kin-ya Tomizaki, Yoshio Hamada, Kenji Usui
    • Journal Title

      Protein & Peptide Letters

      Volume: 25 Issue: 1 Pages: 2-3

    • DOI

      10.2174/092986652501180418150844

    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Journal Article] DNA G-wire formation using an artificial peptide is controlled by protease activity2017

    • Author(s)
      Usui, K., Okada, A., Sakashita, S., Shimooka, M., Tsuruoka, T., Nakano, S., Miyoshi, D., Mashima, T., Katahira, M., Hamada, Y.
    • Journal Title

      Molecules

      Volume: 22 Issue: 11 Pages: 1991-1991

    • DOI

      10.3390/molecules22111991

    • NAID

      120006501324

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07269, KAKENHI-PLANNED-17H06351, KAKENHI-PROJECT-15H03840, KAKENHI-PROJECT-26460163, KAKENHI-PROJECT-16K14042
  • [Journal Article] Recent progress in prodrug design strategies based on generally applicable modifications2017

    • Author(s)
      Yoshio Hamada
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 27 Issue: 8 Pages: 1627-1632

    • DOI

      10.1016/j.bmcl.2017.02.075

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Journal Article] Site-Specific Control of Multiple Mineralizations Using a Designed Peptide and DNA2016

    • Author(s)
      K. Usui, M. Ozaki, A. Yamada, Y. Hamada, T. Tsuruoka, T. Imai, K.-y. Tomizaki
    • Journal Title

      Nanoscale

      Volume: 8 Issue: 39 Pages: 17081-17084

    • DOI

      10.1039/c6nr03468c

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H00828, KAKENHI-PROJECT-26460163
  • [Journal Article] New directions for protease inhibitors directed drug discovery2016

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Journal Title

      Biopolymers

      Volume: 106 Issue: 4 Pages: 563-579

    • DOI

      10.1002/bip.22780

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Journal Article] Novel prodrugs with a spontaneous cleavable guanidine moiety2016

    • Author(s)
      Yoshio Hamada
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 26 Issue: 7 Pages: 1690-1695

    • DOI

      10.1016/j.bmcl.2016.02.060

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Journal Article] A novel N-terminal degradation reaction of peptides via N-amidination2016

    • Author(s)
      Yoshio Hamada
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 26 Issue: 7 Pages: 1685-1689

    • DOI

      10.1016/j.bmcl.2016.02.058

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Journal Article] Novel β-amyloid aggregation inhibitors possessing a turn mimic2015

    • Author(s)
      Yoshio Hamada, Naoko Miyamoto, Yoshiaki Kiso
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 25 Issue: 7 Pages: 1572-1576

    • DOI

      10.1016/j.bmcl.2015.02.016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Journal Article] Drug discovery of β-secretase inhibitors based on quantum chemical interactions for the treatment of Alzheimer's disease2014

    • Author(s)
      Yoshio Hamada
    • Journal Title

      SOJ Pharmacy & Pharmaceutical Sciences

      Volume: 1 Pages: 1-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Journal Article] Drug discovery of β-secretase inhibitors based on quantum chemical interactions for the treatment of Alzheimer's disease2014

    • Author(s)
      Yoshio Hamada
    • Journal Title

      SOJ Pharmacy & Pharmaceutical Sciences

      Volume: 1 Pages: 1-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Journal Article] Structure-activity relationship study of BACE1 inhibitors possessing a chelidonic or 2,6-pyridinedicarboxylic scaffold at the P2 position2014

    • Author(s)
      Yoshio Hamada, Kenji Suzuki, Tomoya Nakanishi, Diganta Sarma, Hiroko Ohta, Ryoji Yamaguchi, Moe Yamasaki, Koushi Hidaka, Shoichi Ishiura, Yoshiaki Kiso
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 26 Issue: 2 Pages: 618-623

    • DOI

      10.1016/j.bmcl.2013.12.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Journal Article] Novel BACE1 inhibitors with a non-acidic heterocycle at the P1′ position2013

    • Author(s)
      Kenji Suzuki, Yoshio Hamada, Jeffrey-Tri Nguyen, Yoshiaki Kiso
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 21 Issue: 21 Pages: 6665-6673

    • DOI

      10.1016/j.bmc.2013.08.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Journal Article] Advances in the identification of beta-secretase inhibitors.2013

    • Author(s)
      Yoshio Hamada
    • Journal Title

      Expert Opinion on Drug Discovery

      Volume: 8 Issue: 6 Pages: 1-23

    • DOI

      10.1517/17460441.2013.784267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-23590137
  • [Journal Article] BACE1 inhibitor peptides: Can an infinitely small kcat value turn the substrate of an enzyme into its inhibitor?2012

    • Author(s)
      Yoshio Hamada, Shoichi Ishiura, Yoshiaki Kiso
    • Journal Title

      ACS Med Chem Lett.

      Volume: 3(3) Issue: 3 Pages: 193-197

    • DOI

      10.1021/ml2002373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-23590137
  • [Journal Article] Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position2012

    • Author(s)
      Yoshio Hamada, Tomoya Nakanishi, Kenji Suzuki, Ryoji Yamaguchi, Takashi Hamada, Koushi Hidaka, Shoichi Ishiura, Yoshiaki Kiso
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 22 Issue: 14 Pages: 4640-4644

    • DOI

      10.1016/j.bmcl.2012.05.089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Journal Article] The application of bioisosteres in drug design for novel drug discovery: focusing on acid protease inhibitors.2012

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Journal Title

      Expert Opinion on Drug Discovery

      Volume: 7(10) Issue: 10 Pages: 903-922

    • DOI

      10.1517/17460441.2012.712513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-23590137
  • [Journal Article] Tripeptidic BACE1 inhibitors devised by in-silico conformational structure- based design.2012

    • Author(s)
      Yoshio Hamada, Harichandra D. Tagad, Yoshinori Nishimura, Shoichi Ishiura, Yoshiaki Kiso
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 22(2) Issue: 2 Pages: 1130-1135

    • DOI

      10.1016/j.bmcl.2011.11.102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-23590137
  • [Journal Article] Structure-guided design and synthesis of P1' position 1-phenylcycloalkyl-amine-derived pentapeptidic BACE1 inhibitors.2011

    • Author(s)
      Harichandra D. Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Koushi Hidaka, Takashi Hamada, Youhei Sohma, Tooru Kimura, Yoshiaki Kiso
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 19 Issue: 17 Pages: 5238-5246

    • DOI

      10.1016/j.bmc.2011.07.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-22790118, KAKENHI-PROJECT-23590137
  • [Presentation] CONSTRUCTION OF PEPTIDE-IMMOBILIZED MICROBEADS SYSTEM FOR ASSESSING SKIN SENSITIZATION2022

    • Author(s)
      Kenji Usui, Masae Fukuda, Aki Nishimura, Fumihiro Kayamori, Yoshio Hamada, Hideto Ariumi
    • Organizer
      第59回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-21K06673
  • [Presentation] 難水溶性物質の皮膚感作性を評価する簡便な試験法の開発(続報)2021

    • Author(s)
      有海秀人、浜田芳男、臼井健二、吉山友二
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-21K06673
  • [Presentation] The solid phase peptide reaction assay(SPRA) using immobilized peptides for safety assessment as an alternatives to animal testing2021

    • Author(s)
      臼井健二、浜田芳男、有海秀人
    • Organizer
      日本動物実験代替法学会第34回大会
    • Data Source
      KAKENHI-PROJECT-21K06673
  • [Presentation] 難水溶性物質の皮膚感作性を評価する簡便な試験法の開発2021

    • Author(s)
      有海秀人、山口聖矢、浜田芳男、臼井健二、吉山友二
    • Organizer
      日本動物実験代替法学会第34回大会
    • Data Source
      KAKENHI-PROJECT-21K06673
  • [Presentation] 皮膚感作性を評価する簡便な試験法の開発2021

    • Author(s)
      有海秀人、山口聖矢、浜田芳男、臼井健二、吉山友二
    • Organizer
      第38回日本薬学会九州山口支部大会
    • Data Source
      KAKENHI-PROJECT-21K06673
  • [Presentation] HIV-1プロテアーゼ阻害剤の水溶性プロドラッグ2020

    • Author(s)
      浜田 芳男、臼井 健二
    • Organizer
      日本薬学会 第140年会
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] A Series of Quinine Prodrugs as Anti-malaria Treatment.2019

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      第56回日本ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] Novel Quinine Prodrugs as Anti-malaria Drug Candidates.2019

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      26th American Peptide Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] マラリア治療薬としての新規なキニーネプロドラッ グ2018

    • Author(s)
      浜田芳男
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] Novel HIV-1 protease inhibitor prodrugs using a degradation reaction of N-amidino-peptides2018

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      35th European Peptide Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] Water soluble prodrug of ritonavir2018

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      10th International Peptide Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] 固定化ペプチドを用いた新規感作性評価法2018

    • Author(s)
      浜田芳男、臼井健二
    • Organizer
      日本薬学会第139年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06562
  • [Presentation] 二種の人工ペプチドを用いたミネラリゼーションによる金-チタニア複合ナノ構造体の作製2017

    • Author(s)
      尾崎誠、坂下俊吾、今井崇人、鶴岡孝章、浜田芳男、富崎欣也、臼井健二
    • Organizer
      日本化学会第97春季年会2017
    • Place of Presentation
      慶応義塾大学日吉キャンパス(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] アルツハイマー病を目指したBACE1阻害剤の開発研究2017

    • Author(s)
      浜田芳男
    • Organizer
      第34回 関西地区ペプチドセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] Novel HIV-1 protease inhibitor prodrug2017

    • Author(s)
      Yoshio Hamada
    • Organizer
      Drug Discovery & Therapy World Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] 外部刺激によりDNAグアニン四重鎖構造形成を抑制するPNAペプチドの設計2017

    • Author(s)
      下岡正幸、岡田亜梨沙、浜田芳男、臼井健二
    • Organizer
      日本化学会第97春季年会2017
    • Place of Presentation
      慶応義塾大学日吉キャンパス(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] Novel water-soluble prodrug of β-secretase inhibitor as an anti-Alzheimer’s disease drug2017

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      第54回日本ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] プロテアーゼを用いたアミロイド線維の分解による新規ナノ構造体の作製2017

    • Author(s)
      鶴見栄太、川田原瑠勇、原田陽滋、浜田芳男、臼井健二
    • Organizer
      日本化学会第97春季年会2017
    • Place of Presentation
      慶応義塾大学日吉キャンパス(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] Design of BACE1 inhibitors possessing a medium-ring structure at the P3 position2017

    • Author(s)
      Yoshio Hamada
    • Organizer
      Drug Discovery & Therapy World Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] 光リンカー含有ペプチド樹脂を用いた難水溶性物質の検出が可能な改良皮膚感作性試験法の構築2017

    • Author(s)
      南野祐槻、宮崎洋、岡平理湖、目片秀明、高石雅之、浜田芳男、臼井健二
    • Organizer
      日本化学会第97春季年会2017
    • Place of Presentation
      慶応義塾大学日吉キャンパス(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] アルツハイマー病を目指したメディシナルケミストリー2017

    • Author(s)
      浜田芳男
    • Organizer
      甲南大学 サイエンスライブチケット part. 27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] A novel N-terminal Degradation Reaction of Peptide via Guanidine Derivatives2016

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      34th European Peptide Symposium
    • Place of Presentation
      Leipzig University (Leipzig, Germany)
    • Year and Date
      2016-09-04
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] 酵素によらない新規なアミド結合の切断反応2016

    • Author(s)
      浜田芳男
    • Organizer
      第21回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪市吹田市)
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] Construction of Nanopeptides by Multiple Mineralization Using DNAs and Designed Peptides2016

    • Author(s)
      M. Ozaki, Y. Hamada, T. Imai,K.-Y. Tomizaki, K. Usui
    • Organizer
      第53回日本ペプチド討論会
    • Place of Presentation
      京都テルサ(京都不京都市)
    • Year and Date
      2016-10-26
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] New N-Terminal Degradation Reaction of Peptides: Application to a Decapeptide2016

    • Author(s)
      Yoshio Hamada, Kenji Usui
    • Organizer
      第53回日本ペプチド討論会
    • Place of Presentation
      京都テルサ(京都不京都市)
    • Year and Date
      2016-10-26
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] Site-Specific Control for Silica and Calcium Carbonate Mineralization Using a PNA Peptide and DNA2016

    • Author(s)
      M. Ozaki, K.-Y. Tomizaki, Y. Hamada, K. Usui
    • Organizer
      34th European Peptide Symposium
    • Place of Presentation
      Leipzig University (Leipzig, Germany)
    • Year and Date
      2016-09-04
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] The significance of protein structure data set choices for in-silico drug discovery: Design of BACE1 inhibitors2014

    • Author(s)
      Yoshio Hamada
    • Organizer
      International Symposium on Compound Design Technologies
    • Place of Presentation
      東京・大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] 2,6-ピリジンジカルボン酸型BACE1阻害剤のSAR研究2013

    • Author(s)
      Yoshio Hamada, Shoichi Ishiura, Yoshiaki Kiso
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] Design of Small-Sized Peptides with BACE1 inhibitory activity2013

    • Author(s)
      Yoshio Hamada, Yoshiaki Kiso
    • Organizer
      23th American Peptide Symposium
    • Place of Presentation
      Waikoloa, USA
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] 低分子化BACE1阻害ペプチドの設計と合成2012

    • Author(s)
      浜田芳男、ハリチャンドラ D. タガッド、木曽良明
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] Development of small BACE1 inhibitor peptides2012

    • Author(s)
      Yoshio Hamada, Yoshiaki kiso
    • Organizer
      The 17th Takeda Symposium on Bioscience
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] Small-sized BACE1 inhibitors: In-silico design and synthesis2012

    • Author(s)
      Yoshio Hamada, Harichandra D. Tagad, Yoshiaki kiso
    • Organizer
      12th Chinese International Peptide Symposium
    • Place of Presentation
      Shenyang, China
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] Design and Synthesis of small BACE1 inhibitor peptides2012

    • Author(s)
      Yoshio Hamada, Harichandra D. Tagad, Yoshiaki kiso
    • Organizer
      32th European Peptide Symposium
    • Place of Presentation
      Athens, Greece
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] トリペプチド型BACE1阻害剤の設計とSAR研究2011

    • Author(s)
      浜田芳男、ハリチャンドラ D. タガッド、木曽良明
    • Organizer
      第48回ペプチド討論会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] BACE1阻害活性を有するペプチドの設計2011

    • Author(s)
      浜田芳男、浜田貴司、木曽良明
    • Organizer
      第16回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      吹田市
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] Small-sized tripeptidic BACE1 inhibitors: Design approach focused on the conformation of inhibitor bound in an enzyme2011

    • Author(s)
      Yoshio Hamada, Harichandra D. Tagad, Yoshiaki Kiso
    • Organizer
      8th AFMC International Medicinal Chemistry Symposium
    • Place of Presentation
      新宿
    • Data Source
      KAKENHI-PROJECT-23590137
  • [Presentation] β-Amyloid aggregation inhibitors possessing a turn mimic template

    • Author(s)
      Yoshio Hamada, Naoko Miyamoto, Yoshiaki Kiso
    • Organizer
      第51回日本ペプチド討論会
    • Place of Presentation
      徳島
    • Year and Date
      2014-10-22 – 2014-10-24
    • Data Source
      KAKENHI-PROJECT-26460163
  • [Presentation] β-Amyloid aggregation inhibitors possessing a turn mimic template

    • Author(s)
      Yoshio Hamada, Naoko Miyamoto, Yoshiaki Kiso
    • Organizer
      第51回日本ペプチド討論会
    • Place of Presentation
      徳島
    • Year and Date
      2014-10-22 – 2014-10-24
    • Data Source
      KAKENHI-PROJECT-23590137
  • 1.  Ito Akihiko (80273647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  古徳 直之 (20362618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  有海 秀人 (70454874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  臼井 健二 (70543792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  栢森 史浩 (60971645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  HIDAKA Koushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  SOHMA Youhei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  川野 竜司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  木曽 良明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 10.  真嶋 司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  木村 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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