Wakisaka Keiko 脇坂啓子 (辻啓子)

… Alternative Names

脇坂啓子ワキサカケイコ(ツジケイコ)

辻啓子

TSUJI Keiko 辻啓子

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Researcher Number	70432309
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2021 – 2022: 順天堂大学, 医学部, 博士研究員 2007 – 2009: 滋賀医科大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator midbrain / Parkinson’s disease / neurogenesis / astrocyte / mitophagy / PINK1 / Parkin / 若年性パーキンソン病 / 生理的マイトファジー / アストロサイト / 中脳発生 … More Except Principal Investigator … More イオンチャネル / 蛋白質 / 遺伝子 / 生理学 Less

Roles of PINK1-Parkin on the differentiation of astrocytes in development of midbrainPrincipal Investigator
- Principal Investigator
  
  脇坂啓子 (辻啓子)
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Juntendo University
Genotype-phenotype relation study on inherited cardiac arrhythmias as ion hcannel diseases
- Principal Investigator
  
  HORIE Minoru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Shiga University of Medical Science

All 2021 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Inhibitory actions of LY294002, a phosphatidylinositol 3-kinase inhibitor, on the human Kv1.5 channel2009
- Author(s)
  Wu J, Ding WG, Matsuura H, Tsuji K, Zang WJ, Horie M.
- Journal Title
  
  Brit J Pharm 56
  
  Pages: 377-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Novel KCNE3mutations interact with KCNQ1and cause long QT syndrome2009
- Author(s)
  Ohno S, Toyoda F, Zankov D, Yoshida H, Makiyama T, Tsuji K, Honda T, Obayashi K, Matsuura H, Shimizu W, Miyamoto Y, Kamakura S, Kita T, Horie M.
- Journal Title
  
  Hum Muta 30
  
  Pages: 557-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome2009
- Author(s)
  Ohno S, Tsuji K, Horie M, et al
- Journal Title
  
  Hum Mutat 30
  
  Pages: 557-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Adrenergic regulation of the rapid component of delayed rectifier K+ current : Implications for arrhythmogenesis in LQT2 patients2009
- Author(s)
  Zankov DP, Tsuji K, Horie M, et al
- Journal Title
  
  Heart Rhythm 6(7)
  
  Pages: 1038-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Association between polymorphism of the AGTR1 and cardiovascular events in a Japanese general sample (The Shigaraki Study)2009
- Author(s)
  Tamaki S, Nakamura Y, Tabara Y, Okamura T, Kanda H, Kita Y, Kadowaki T, Tsujita Y, Turin T C, Horie M, Miki T, Ueshima H.
- Journal Title
  
  Int J Cardiol 136
  
  Pages: 354-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Adrenergic regulation of the rapid component of delayed rectifier K^+ current : Implications for arrhythmogenesis in LQT2 patients2009
- Author(s)
  Zankov DP, Yoshida H, Tsuji K, Toyoda F, Ding WG, Matsuura H, Horie M
- Journal Title
  
  Heart Rhythm 6
  
  Pages: 1038-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Age-and genotype-specific triggers for life-threatening arrhythmia in the genotyped long-QT syndrome2008
- Author(s)
  Sakaguchi T, Itoh H, Tsuji K, Horie M, et al
- Journal Title
  
  J Cardiovasc Electrophysiol 19(8)
  
  Pages: 794-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Mutation analysis of the glycerol-3 phosphate dehydrogenase-1 like (GPD1L) gene in Japanese patients with Brugada syndrome2008
- Author(s)
  Makiyama T, Tsuji K, Horie M, et al
- Journal Title
  
  Circ J 72
  
  Pages: 1705-1706
- NAID
  110006935616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] A novel SCN5Again-of-function mutation M1875T associated with familial atrial fibrillation2008
- Author(s)
  Makiyama T, Tsuji K, Itoh H, Horie M, et al
- Journal Title
  
  J Am Coll Cardiol 52(16)
  
  Pages: 1326-1334
- NAID
  10024457085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Hydroxyzine, a First Generation H1-Receptor Antagonist, Inhibits Human Ether-a-go-go?Related Gene (HERG) Current and Causes Syncope in a Patient With the HERG Mutation2008
- Author(s)
  Sakaguchi T, Itoh H, Tsuji K, Horie M, et al
- Journal Title
  
  J Pharmacol Sci 108
  
  Pages: 462-471
- NAID
  130000075877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Genotype-phenotype correlations of KCNJ2 mutations in Japanese patients with Andersen-Tawil syndrome2007
- Author(s)
  Haruna Y, Tsuji K, Horie M, et al
- Journal Title
  
  Hum Mutat 28(2)
  
  Pages: 208-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene2007
- Author(s)
  Tsuji K, Horie M, et al
- Journal Title
  
  J Mol Cell Cardiol 42(3)
  
  Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome2007
- Author(s)
  Itoh H, Tsuji K, Horie M, Imoto K.
- Journal Title
  
  Int J Cardiol 121(3)
  
  Pages: 249-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene2007
- Author(s)
  Tsuji K
- Journal Title
  
  J Mol Cell Cardiol 42
  
  Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] A family of hereditary long QT syndrome caused by Q738X HERG mutation
- Author(s)
  Yasuda S, Hiramatsu S, Odashiro K, Maruyama T, Tsuji K, Horie M.
- Journal Title
  
  Int J Cardiol. (in press)
- Data Source
  KAKENHI-PROJECT-19390212
[Journal Article] A family of hereditary long QT syndrome caused by Q738X HERG mutation
- Author(s)
  Yasuda S, Tsuji K, Horie M, et al
- Journal Title
  
  Int J Cardiol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390212
[Presentation] 中脳ドパミン神経を取り巻くアストロサイトの発生様式2021
- Author(s)
  脇坂啓子
- Organizer
  第44回分子生物学会
- Data Source
  KAKENHI-PROJECT-21K15631
[Presentation] Multiple mechanisms underlie long QT syndrome by the change of amino acid R259 in the intracellular S4-S5 linker of KCNQ12009
- Author(s)
  Ohno S, Tsuji K, Makiyama T, Nishio Y, Akao M, Kita T, Horie M
- Organizer
  Cardiorhythm2009
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-19390212
[Presentation] Identification and functional characterization of a novel intronic splicing mutation in KCNQl associated with long QT syndrome2009
- Author(s)
  Tsuji K
- Organizer
  第7 3回日本循環器学会総会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390212
[Presentation] KCNQ1遺伝子上の高頻度スプライス変異によるQT延長症候群発症のメカニズム2007
- Author(s)
  辻啓子
- Organizer
  第9回日本RNA学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390212

1. HORIE Minoru (90183938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
2. ITOH Hideki (30402738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Wakisaka Keiko 脇坂 啓子 (辻 啓子)

脇坂 啓子 ワキサカ ケイコ(ツジケイコ)

辻啓子

TSUJI Keiko 辻 啓子

Research Projects

Research Products

Co-Researchers

Roles of PINK1-Parkin on the differentiation of astrocytes in development of midbrainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genotype-phenotype relation study on inherited cardiac arrhythmias as ion hcannel diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibitory actions of LY294002, a phosphatidylinositol 3-kinase inhibitor, on the human Kv1.5 channel2009

Author(s)

Journal Title

Data Source

[Journal Article] Novel KCNE3mutations interact with KCNQ1and cause long QT syndrome2009

Author(s)

Journal Title

Data Source

[Journal Article] Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome2009

Author(s)

Journal Title

Data Source

[Journal Article] Adrenergic regulation of the rapid component of delayed rectifier K+ current : Implications for arrhythmogenesis in LQT2 patients2009

Author(s)

Journal Title

Data Source

[Journal Article] Association between polymorphism of the AGTR1 and cardiovascular events in a Japanese general sample (The Shigaraki Study)2009

Author(s)

Journal Title

Data Source

[Journal Article] Adrenergic regulation of the rapid component of delayed rectifier K^+ current : Implications for arrhythmogenesis in LQT2 patients2009

Author(s)

Journal Title

Data Source

[Journal Article] Age-and genotype-specific triggers for life-threatening arrhythmia in the genotyped long-QT syndrome2008

Author(s)

Journal Title

Data Source

[Journal Article] Mutation analysis of the glycerol-3 phosphate dehydrogenase-1 like (GPD1L) gene in Japanese patients with Brugada syndrome2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A novel SCN5Again-of-function mutation M1875T associated with familial atrial fibrillation2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Hydroxyzine, a First Generation H1-Receptor Antagonist, Inhibits Human Ether-a-go-go?Related Gene (HERG) Current and Causes Syncope in a Patient With the HERG Mutation2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Genotype-phenotype correlations of KCNJ2 mutations in Japanese patients with Andersen-Tawil syndrome2007

Author(s)

Journal Title

Data Source

[Journal Article] Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene2007

Author(s)

Journal Title

Data Source

[Journal Article] A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome2007

Author(s)

Journal Title

Data Source

[Journal Article] Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene2007

Author(s)

Journal Title

Data Source

[Journal Article] A family of hereditary long QT syndrome caused by Q738X HERG mutation

Author(s)

Wakisaka Keiko 脇坂啓子 (辻啓子)

脇坂啓子ワキサカケイコ(ツジケイコ)

TSUJI Keiko 辻啓子