Masuda Mari 増田万里

… Alternative Names

Researcher Number	70435717
Other IDs
Affiliation (Current)	2022: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2016 – 2020: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2009: 国立がんセンター研究所, 研究員 2007: 東京大学, 国立がんセンター研究所・腫瘍ゲノム解析・報研究部, 研究員
Review Section/Research Field	Principal Investigator Tumor diagnostics / Tumor therapeutics / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 逆相タンパクアレイ / RPPA / 大腸がん / Wnt シグナル / 分子標的治療薬 / 高精度医療 / Wntシグナル / トランスレーショナルリサーチ / 細胞・組織 / 癌 … More Except Principal Investigator アレル特異的発現 / RNA difference plot / CADM1 / 非小細胞肺がん / ATL / 細胞接着分子 / RAC / Tiam1 / 細胞運動性 / 上皮様形態形成 / 4.1N / アレル / 遺伝子発現 / がん抑制遺伝子 / 細胞接着 / RDP / 遺伝子欠損マウス / 肺腺癌 / 肺腺腫 / 浸潤 / TSLL2 / CADM4 / DAL-184.1B / メチル化 / 賢明細胞がん / 前立腺がん / DNA修復酵素遺伝子 / TSLL2遺伝子 / DAL-1 / 4.1B遺伝子 / 腎明細胞がん / 予後因子 Less

Development of a diagnostic platform for precision oncology by applying reverse-phase phosphoprotein array to an analysis of formalin-fixed paraffin-embedded (FFPE) tissuePrincipal Investigator
- Principal Investigator
  
  増田万里
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
Identification of regulatory components of Wnt signaling in beta-catenin and T-cell factor-4 transcriptional complex as therapeutic targets for colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Masuda Mari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  National Cancer Center Japan
Development of reverse-phase protein array platform for analyzing tissue samples and identification of biomarkers to guide the use of a TNIK inhibitorPrincipal Investigator
- Principal Investigator
  
  Masuda Mari
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnostics
- Research Institution
  National Cancer Center Japan
Molecular understanding and diagnosis of human cancer through the structural, functional and expression analysis of cancer related genes.
- Principal Investigator
  
  MURAKAMI Yoshinori
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2021 2020 2019 2018 2017 2016 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] Biomarkers in Cancer Therapy2019
- Author(s)
  Akihiko Miyanaga, Mari Masuda, Tesshi Yamada
- Total Pages
  5
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-16K14627
[Book] Chapter 10. Biomarkers of Lung Cancer: Liquid Biopsy Comes of Age. Biomarkers in Cancer Therapy.2019
- Author(s)
  Miyanaga A., Masuda M., Yamada T.
- Total Pages
  5
- Publisher
  Springer Nature
- ISBN
- Data Source
  KAKENHI-PROJECT-17H03603
[Book] Chapter 15. Utility of Reverse-phase Protein Array for Refining Precision Oncology, Reverse-Phase Protein Array, Advances in Experimental Medicine and Biology2019
- Author(s)
  Masuda M., Yamada T.
- Total Pages
  8
- Publisher
  Springer Nature
- ISBN
- Data Source
  KAKENHI-PROJECT-17H03603
[Book] 大腸がんの幹細胞増殖を抑える新規化合物発見から創薬へ2017
- Author(s)
  増田万里
- Total Pages
  1
- Publisher
  日経サイエンス
- Data Source
  KAKENHI-PROJECT-17H03603
[Book] 大腸がんの幹細胞増殖を抑える新規化合物発見から創薬へ2017
- Author(s)
  増田万里
- Total Pages
  1
- Publisher
  日経サイエンス
- Data Source
  KAKENHI-PROJECT-16K14627
[Journal Article] Pharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846.2021
- Author(s)
  Sugano Teppei、Masuda Mari、Takeshita Fumitaka、Motoi Noriko、Hirozane Toru、Goto Naoko、Kashimoto Shigeki、Uno Yuko、Moriyama Hideki、Sawa Masaaki、Nagakawa Yuichi、Tsuchida Akihiko、Seike Masahiro、Gemma Akihiko、Yamada Tesshi
- Journal Title
  
  Br J Cancer
  
  Volume: 124 Pages: 228-236
- DOI
  10.1038/s41416-020-01162-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K20474, KAKENHI-PROJECT-20K18040
[Journal Article] Direct conversion of osteosarcoma to adipocytes by targeting TNIK2021
- Author(s)
  Hirozane Toru、Masuda Mari、Sugano Teppei、Sekita Tetsuya、Goto Naoko、Aoyama Toru、Sakagami Takato、Uno Yuko、Moriyama Hideki、Sawa Masaaki、Asano Naofumi、Nakamura Masaya、Matsumoto Morio、Nakayama Robert、Kondo Tadashi、Kawai Akira、Kobayashi Eisuke、Yamada Tesshi
- Journal Title
  
  JCI Insight
  
  Volume: 6
- DOI
  10.1172/jci.insight.137245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K20474, KAKENHI-PROJECT-20K18040, KAKENHI-PROJECT-19J21415
[Journal Article] Whole-exome and RNA sequencing of pulmonary carcinoid reveals chromosomal rearrangements associated with recurrence2020
- Author(s)
  Miyanaga Akihiko、Masuda Mari、Motoi Noriko、Tsuta Koji、Nakamura Yuka、Nishijima Nobuhiko、Watanabe Shun-ichi、Asamura Hisao、Tsuchida Akihiko、Seike Masahiro、Gemma Akihiko、Yamada Tesshi
- Journal Title
  
  Lung Cancer
  
  Volume: 145 Pages: 85-94
- DOI
  10.1016/j.lungcan.2020.03.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K20474
[Journal Article] Feasibility of Targeting Traf2-and-Nck-Interacting Kinase in Synovial Sarcoma.2020
- Author(s)
  Sekita Tetsuya、Yamada Tesshi、Kobayashi Eisuke、Yoshida Akihiko、Hirozane Toru、Kawai Akira、Uno Yuko、Moriyama Hideki、Sawa Masaaki、Nagakawa Yuichi、Tsuchida Akihiko、Matsumoto Morio、Nakamura Masaya、Nakayama Robert、Masuda Mari
- Journal Title
  
  Cancers
  
  Volume: 12 Pages: 1258-1258
- DOI
  10.3390/cancers12051258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09589, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K20474, KAKENHI-PROJECT-20K18040, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-19J21415
[Journal Article] Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance2020
- Author(s)
  Uchihara T, Miyake K, Yonemura A, Komohara Y, Itoyama R, Koiwa M, Yasuda T, Arima K, Harada K, Eto K, Hayashi H, Iwatsuki M, Iwagami S, Baba Y, Yoshida N, Yashiro M, Masuda M, Ajani Jaffer A, Tan Patrick, Baba H, Ishimoto T
- Journal Title
  
  Cancer Research
  
  Volume: 80 Pages: 3222-3235
- DOI
  10.1158/0008-5472.can-19-3803
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09177, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16720, KAKENHI-PROJECT-19K16749
[Journal Article] Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma2020
- Author(s)
  Sugano T, Yoshida M, Masuda M, Ono M, Tamura K, Kinoshita T, Tsuda H, Honda K, Gemma A, Yamada T
- Journal Title
  
  British Journal of Cancer
  
  Volume: 122 Pages: 1811-1817
- DOI
  10.1038/s41416-020-0821-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20474, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-19H03856
[Journal Article] Hunting hidden pieces of signaling pathways in hepatocellular carcinoma.2019
- Author(s)
  Masuda M.
- Journal Title
  
  HepatoBiliary Surg Nutr.
  
  Volume: 1 Pages: 74-76
- DOI
  10.21037/hbsn.2018.10.10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03603, KAKENHI-PROJECT-16K14627
[Journal Article] Emergence of TNIK inhibitors in cancer therapeutics2017
- Author(s)
  Yamada T, Masuda M.
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Pages: 818-823
- DOI
  10.1111/cas.13203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627, KAKENHI-PROJECT-17H03603
[Journal Article] Signaling pathway profiling using reverse-phase protein array and its clinical applications2017
- Author(s)
  Masuda Mari、Yamada Tesshi
- Journal Title
  
  Expert Review of Proteomics
  
  Volume: 14 Pages: 607-615
- DOI
  10.1080/14789450.2017.1344101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627, KAKENHI-PROJECT-17H03603
[Journal Article] The emergence of TNIK as a therapeutic target for colorectal cancer2017
- Author(s)
  Masuda M, Yamada T.
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 4 Pages: 353-355
- DOI
  10.1080/14728222.2017.1297799
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627, KAKENHI-PROJECT-17H03603
[Journal Article] TNIK Inhibition Abrogates Colorectal Cancer Stemness.2016
- Author(s)
  Masuda M, Uno Y, Ohbayashi N, Ohata H, Mimata A, Kukimoto-Niino M, Moriyama H, Kashimoto S, Inoue T, Goto N, Okamoto K, Shirouzu M, Sawa M, Yamada T.
- Journal Title
  
  Nature Commun.
  
  Volume: - Pages: 12586-12586
- DOI
  10.1038/ncomms12586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01581, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-16K14627
[Journal Article] CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I (HTLV-I) transformed cells and adult T-cell leukemia (ATL) cells.2010
- Author(s)
  Masuda M, Maruyama T, Ohta T, Ito A, Hayashi T, Tsukasaki K, Kamihira S, Yamaoka S, Hoshino H, Yoshida T, Watanabe T, Stanbridge EJ, Murakami Y.
- Journal Title
  
  Journal of Biological Chemistry 285
  
  Pages: 15511-15522
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I (HTLV-I) transformed cells and adult T-cell leukemia (ATL) cells.2010
- Author(s)
  Masuda M, Ito A, Murakami Y, et al.(最終著者)
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 15511-15522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Tumor suppressor CADM1 is involved in epithelial cell structure.2009
- Author(s)
  Sakurai-Yageta M, Masuda M, Tsuboi Y, Ito A, Murakami Y.
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 977-982
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Cell adhesion molecule 1 is a novel pancreatic-islet cell adhesion molecule that mediates nerve-islet cell interactions.2008
- Author(s)
  Koma Y, Furuno T, Hagiyama M, Hamaguchi K, Nakanishi M, Masuda M, Hirota S, Yokozaki H, Ito A
- Journal Title
  
  Gastroenterology. 134
  
  Pages: 1544-1554
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Disruption of spermatogenic cell adhesion and male infertility in mice lacking TSLC1/IGSF4,an immunoglobulin superfamily cell adhesion molecule.2006
- Author(s)
  Yamada, D, Yoshida, M, Williams, YN, Fukami, T, Kikuchi, S, Masuda, Maruyama, M, Ohta, T, Nakae, D, Maekawa, A, Kitamura, T, Murakami, Y.
- Journal Title
  
  Molecular and Cellular Biology (in press)
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Promoter Hypermethylation of the Potential Tumor Suppressor DAL-1/4.1B Gene in Renal Clear Cell Carcinoma.2006
- Author(s)
  Yamada D, Kikuchi S, Williams YN, Sakurai-Yageta M, Masuda M, Maruyama T, Tomita K, Gutmann DH, Kakizoe T, Kitamura T, Murakami Y
- Journal Title
  
  Int J Cancer. 118
  
  Pages: 916-923
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Cell adhesion and prostate tumor suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4.2006
- Author(s)
  Williams, YN, Masuda, M, Sakurai-Yageta, M, Maruyama, T, Shibuya, M, Murakami, Y.
- Journal Title
  
  Oncogene 25
  
  Pages: 1446-1453
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Cell adhesion and prostate tumor suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4.2006
- Author(s)
  Williams YN, Masuda M, Sakurai-Yageta M, Maruyama T, Shibuya M, Murakami Y
- Journal Title
  
  Oncogene. 25
  
  Pages: 1446-1453
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Disruption of spermatogenic cell adhesion and male infertility in mice lacking TSLC1/IGSF4, an immunoglobulin superfamily cell adhesion molecule.2006
- Author(s)
  Yamada D, Yoshida M, Williams YN, Fukami T, Kikuchi S, Masuda M, Maruyama M, Ohta T, Nakae D, Maekawa A, Kitamura T, Murakami Y
- Journal Title
  
  Mol Cell Biol. 26
  
  Pages: 3610-3624
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Promoter Hypermethylation of the Potential Tumor Suppressor DAL-1/4.1B Gene i Renal Cancer Cell Carcinoma.2006
- Author(s)
  Yamada, D, Kikuchi, S, Williams, YN, Sakurai-Yageta, M, Masuda, M, Murayama, T, Tomita, K, Gutmann, DH, Kakizoe, T, Kitamura, T, Murakami, Y.
- Journal Title
  
  International Journal of Cancer 118
  
  Pages: 916-923
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Promoter methylation of the DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer.2005
- Author(s)
  Kikuchi, S, Yamada, D, Fukami, T, Masuda, M, Sakurai-Yageta, M, Williams, YN, Maruyama, T, Asamura, H, Matsuno, Y, Onizuka, M, Murakami, Y.
- Journal Title
  
  Clinical Cancer Research 11
  
  Pages: 2954-2961
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] TSLC (tumor suppressor in lung cancer) 1 suppresses epithelial cell scattering and tubulogenesis.2005
- Author(s)
  Masuda, M, Kikuchi, S, Maruyama, T, Sakurai-Yageta, M, Williams, YN, Ghosh HP, Murakami, Y.
- Journal Title
  
  Journal of Biological Chemistry 280
  
  Pages: 42164-42171
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] Promoter methylation of the DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer.2005
- Author(s)
  Kikuchi S, Yamada D, Fukami T, Masuda M, Sakurai-Yageta M, Williams YN, Maruyama T, Asamura H, Matsuno Y, Onizuka M, Murakami Y
- Journal Title
  
  Clin Cancer Res. 11
  
  Pages: 2954-2961
- Data Source
  KAKENHI-PROJECT-17015048
[Journal Article] TSLC (tumor suppressor in lung cancer)1 suppresses epithelial cell scattering and tubulogenesis.2005
- Author(s)
  Masuda M, Kikuchi S, Maruyama T, Sakurai-Yageta M, Williams YN, Ghosh HP, Murakami Y
- Journal Title
  
  J Biol Chem. 280
  
  Pages: 42164-42171
- Data Source
  KAKENHI-PROJECT-17015048
[Patent] がんの診断、処置および/または予防、および/または浸潤・転移の抑制のための方法2005
- Inventor(s)
  村上善則、増田万里
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2005-266127
- Filing Date
  2005-09-13
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] Identification of therapeutic target and potential companion marker for molecular-targeted therapy of malignant pleural mesothelioma2020
- Author(s)
  Toru Aoyama, Noriko Motoi, Naoko Goto, Riko Nakagaw, Masahiro Seike, Mari Masuda
- Organizer
  第７９回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07690
[Presentation] Utility of Reverse-Phase Protein Array for Refining Precision Oncology2020
- Author(s)
  Mari Masuda
- Organizer
  Korean Society for Biochemistry and Molecular Biology　（KSBMB） International Conference 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07690
[Presentation] 大腸がん幹細胞の遺伝子転写を標的とした新規分子標的治療薬の開発.2019
- Author(s)
  増田万里、弘實透、宇野佑子、澤匡明、山田哲司.
- Organizer
  第14回日本がん分子標的治療学会・TRワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Application of the TNIK inhibitor, NCB-0846, to colorectal cancer treatment and beyond.2019
- Author(s)
  Mari Masuda
- Organizer
  8th Global Reverse Phase Protein Array Workshop,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] 肉腫のプロテオゲノミクス解析：国際がんプロテオゲノミクスコンソーシアム（ICPC）.2018
- Author(s)
  近藤格、服部恵美、塩澤久美子、尾野雅哉、増田万里、山田哲司.
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] 肉腫のプロテオゲノミクス解析：国際がんプロテオゲノミクスコンソーシアム（ICPC）.2018
- Author(s)
  近藤格、服部恵美、尾野雅哉、増田万里、川井章、山田哲司.
- Organizer
  第14 日本臨床プロテオゲノミクス研究会.
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Traf2-and Nck-interacting kinase (TNIK) inhibitor, NCB-0846, suppresses TGF-β1-induced epithelial-mesenchymal transition in lung cancer.2018
- Author(s)
  T. Sugano, M. Masuda, Y. Uno, N. Goto, M. Seike, M. Sawa, A. Gemma, T. Yamada.
- Organizer
  AACR Annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Traf2-and Nck-interacting kinase (TNIK) inhibitor, NCB-0846, suppresses TGF-β1-induced epithelial-mesenchymal transition in lung cancer.2018
- Author(s)
  T. Sugano, M. Masuda, Y. Uno, N. Goto, M. Seike, M. Sawa, A. Gemma, T. Yamada.
- Organizer
  AACR Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] がん精密医療における逆相タンパク基盤の有用性2018
- Author(s)
  増田万里
- Organizer
  第15回北里疾患プロテオーム研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] TRAF2 and NCK-interacting protein kinase (TNIK) regulates cancer stemness and adipogenesis of osteosarcoma cells.2018
- Author(s)
  T. Hirozane, M. Masuda, N. Goto, T. Sugano, N. Asano, E. Kobayashi, K. Horiuchi, H. Morioka, A. Kawai, M. Sawa, M. Matsumoto, M. Nakamura, T. Yamada.
- Organizer
  AACR Annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Clarification of the Signaling Network Affected by the TNIK Inhibitor, NCB-0846, Using Reverse-phase Protein Array.2018
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Naoko Goto, Masaaki Sawa and Tesshi Yamada.
- Organizer
  The Human Proteome Organization (HUPO) 2018 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] TNIK is a novel molecular target for osteosarcoma treatment and controls osteosarcoma cell fate.2018
- Author(s)
  Toru Hirozane, Mari Masuda, Naoko Goto, Teppei Sugano, Naofumi Asano, Eisuke Kobayashi, Akira Kawai, Keisuke Horiuchi, Morio Matsumoto, Masaya Nakamura, Masaaki Sawa, Hideo Morioka, Tesshi Yamada.
- Organizer
  2018 CTOS Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] 網羅的ゲノム解析を用いた肺カルチノイドの新規治療標的遺伝子の同定.2018
- Author(s)
  宮永晃彦、増田万里、蔦幸治、西島伸彦、清家正博、浅村尚生、弦間昭彦、山田哲司.
- Organizer
  第59回日本肺癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] TNIK is a novel molecular target for osteosarcoma treatment and controls osteosarcoma cell fate.2018
- Author(s)
  Toru Hirozane, Mari Masuda, Naoko Goto, Teppei Sugano, Naofumi Asano, Eisuke Kobayashi, Akira Kawai, Keisuke Horiuchi, Morio Matsumoto, Masaya Nakamura, Masaaki Sawa, Hideo Morioka, Tesshi Yamada.
- Organizer
  2018 CTOS Annual Meeting,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] がん高精度医療における逆相タンパクアレイ基盤の有用性2018
- Author(s)
  増田万里
- Organizer
  北里疾患プロテオーム研究会　増田
- Invited
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] 網羅的ゲノム解析を用いた肺カルチノイドの新規治療標的遺伝子の同定.2018
- Author(s)
  宮永晃彦、増田万里、蔦幸治、西島伸彦、清家正博、浅村尚生、弦間昭彦、山田哲司.
- Organizer
  第59回日本肺癌学会学術総会,
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] 大腸がん幹細胞の遺伝子転写を標的とした新規分子標的治療薬の開発.2018
- Author(s)
  増田万里、弘實透、宇野佑子、澤匡明、山田哲司.
- Organizer
  第14回日本がん分子標的治療学会・TRワークショップ
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] 肉腫のプロテオゲノミクス解析：国際がんプロテオゲノミクスコンソーシアム（ICPC）.2018
- Author(s)
  近藤格、服部恵美、塩澤久美子、尾野雅哉、増田万里、山田哲司.
- Organizer
  第14 日本臨床プロテオゲノミクス研究会.
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Clarification of the Signaling Network Affected by the TNIK Inhibitor, NCB-0846, Using Reverse-phase Protein Array.2018
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Naoko Goto, Masaaki Sawa and Tesshi Yamada.
- Organizer
  The Human Proteome Organization (HUPO) 2018 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Application of the TNIK inhibitor, NCB-0846, to colorectal cancer treatment and beyond.2018
- Author(s)
  Masuda M
- Organizer
  8th Global Reverse Phase Protein Array Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] 肉腫のプロテオゲノミクス解析：国際がんプロテオゲノミクスコンソーシアム（ICPC）.2018
- Author(s)
  近藤格、服部恵美、尾野雅哉、増田万里、川井章、山田哲司.
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] TRAF2 and NCK-interacting protein kinase (TNIK) regulates cancer stemness and adipogenesis of osteosarcoma cells.2018
- Author(s)
  T. Hirozane, M. Masuda, N. Goto, T. Sugano, N. Asano, E. Kobayashi, K. Horiuchi, H. Morioka, A. Kawai, M. Sawa, M. Matsumoto, M. Nakamura, T. Yamada.
- Organizer
  AACR Annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] A novel TNIK inhibitor potently downregulates cancer stem cell population through attenuation of Wnt signaling2017
- Author(s)
  Yuko Uno, Hideki Moriyama, Shigeki Kashimoto, Mari Masuda, Masaaki Sawa, Tesshi Yamada
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Preclinical development of NCB-0846, a novel TNIK inhibitor that blocks Wnt signaling in colorectal cancer2017
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Hideki Moriyama, Shigeki Kashimoto, Naoko Goto, Masaki Sawa and Tesshi Yamada
- Organizer
  第76回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Preclinical development of NCB-0846, a novel TNIK inhibitor that blocks Wnt signaling in colorectal cancer2017
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Hideki Moriyama, Shigeki Kashimoto, Naoko Goto, Masaki Sawa and Tesshi Yamada
- Organizer
  第76回日本癌学会月術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] TRAF2 and NCK-interacting protein kinase（TNIK）は骨肉腫の分子標的となりうる2017
- Author(s)
  弘實透，増田万里，浅野尚文，小林英介，川井章，堀内圭輔，松本守雄，澤匡明，森岡秀夫，中村雅也，山田哲司
- Organizer
  日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] 新規TNIK 阻害薬によるEMT 制御2017
- Author(s)
  菅野哲平、増田万里、宇野佑子、森山英樹、後藤尚子、清家正博、澤匡明、弦間昭彦、山田哲司
- Organizer
  第76回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] がん高精度医療における逆相タンパクアレイ基盤の有用性2017
- Author(s)
  増田万里
- Organizer
  北里疾患プロテオーム研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Elucidation of Signaling Pathways Affected by TNIK Inhibitor, NCB-0846, Using Reverse-Phase Protein Array2017
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Masaaki Sawa and Tesshi Yamada
- Organizer
  RPPA Global Workshop 2017 Dublin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] A novel TNIK inhibitor potently downregulates cancer stem cell population through attenuation of Wnt signaling2017
- Author(s)
  Yuko Uno, Hideki Moriyama, Shigeki Kashimoto, Mari Masuda, Masaaki Sawa, Tesshi Yamada
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] 骨肉腫治療におけるTNIK阻害剤の可能性2017
- Author(s)
  弘實　透，増田万里，後藤尚子，菅野哲平，浅野尚文，小林英介，川井　章，堀内圭輔，松本守雄，中村雅也，澤　匡明，森岡秀夫，山田哲司
- Organizer
  分子腫瘍マーカー研究会
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Therapeutic target discovery by cancer proteomics in the era of large-scale genome-resequencing2017
- Author(s)
  Tesshi Yamada and Mari Masuda
- Organizer
  HUPO 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] TNIK 阻害剤はWnt シグナルを減弱させてがん幹細胞画分を減少させる2017
- Author(s)
  宇野佑子、増田万里、森山英樹、澤匡明、山田哲司
- Organizer
  第76回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] TNIK 阻害剤はWnt シグナルを減弱させてがん幹細胞画分を減少させる2017
- Author(s)
  宇野佑子、増田万里、森山英樹、澤匡明、山田哲司
- Organizer
  第76回日本癌学会月術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Application of Proteomic Technology in Development of Novel TNIK Inhibitor Blocking Wnt Signaling2017
- Author(s)
  Mari Masuda, Yuko Uno, Shigeki Kashimoto, Hideki Moriyama, Masaaki Sawa and Tesshi Yamada
- Organizer
  日本プロテオーム学会２０１７年大会JHUPO第１５回大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] Therapeutic target discovery by cancer proteomics in the era of large-scale genome-resequencing2017
- Author(s)
  Tesshi Yamada and Mari Masuda
- Organizer
  HUPO 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] TNIK は骨肉腫の新規治療標的となりうる2017
- Author(s)
  弘實透、増田万里、後藤尚子、浅野尚文、小林英介、川井章、堀内圭輔、澤匡明、山田哲司
- Organizer
  第76回日本癌学会月術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03603
[Presentation] 新規TNIK 阻害薬によるEMT 制御2017
- Author(s)
  菅野哲平、増田万里、宇野佑子、森山英樹、後藤尚子、清家正博、澤匡明、弦間昭彦、山田哲司
- Organizer
  第76回日本癌学会月術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] TNIK は骨肉腫の新規治療標的となりうる2017
- Author(s)
  弘實透、増田万里、後藤尚子、浅野尚文、小林英介、川井章、堀内圭輔、澤匡明、山田哲司
- Organizer
  第76回日本癌学会月術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Elucidation of Signaling Pathways Affected by TNIK Inhibitor, NCB-0846, Using Reverse-Phase Protein Array2017
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Masaaki Sawa and Tesshi Yamada
- Organizer
  RPPA Global Workshop 2017 Dublin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Application of Proteomic Technology in Development of Novel TNIK Inhibitor Blocking Wnt Signaling2017
- Author(s)
  Mari Masuda, Yuko Uno, Shigeki Kashimoto, Hideki Moriyama, Masaaki Sawa and Tesshi Yamada
- Organizer
  日本プロテオーム学会２０１７年大会JHUPO第１５回大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Preclinical Characterization Of A Novel TNIK Inhibitor, NCB-0846, By Proteomic Profiling Of Signaling Pathways Using Reverse-Phase Protein Array2016
- Author(s)
  Mari Masuda, Takeomi Inoue, Yuko Uno, Masaaki Sawa and Tesshi Yamada
- Organizer
  ６th Global Reverse Phase Protein Array Workshop
- Place of Presentation
  NMI Naural and Medical Science Institute at the University of Tubingen, Germany
- Year and Date
  2016-09-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Developing therapeutic intervention of Wnt signaling pathway in colorectal cancer2016
- Author(s)
  Mari Masuda, Yuko Uno, Hirokazu Ohata, Hideki Moriyama, Naoko Goto, Koji Okamoto, Masaki Sawa and Tesshi Yamada
- Organizer
  The 76the Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Pacifico Yokohama, Yokohama, Japan
- Year and Date
  2016-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] A novel Traf2- and Nck-interacting kinase inhibitor suppresses epithelial mesenchymal transition2016
- Author(s)
  Teppei Sugano, Mari Masuda, Yuko Uno, Hideki Moriyama, Naoko Goto, Masahiro Seike, Masaaki Sawa, Akihiko Gemma, Tesshi Yamada
- Organizer
  The 76the Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Pacifico Yokohama, Yokohama, Japan
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14627
[Presentation] Involvement of a cell adhesion molecule CADM1/TSLC1 in oncogenesis2010
- Author(s)
  Nagata M, Sakurai-Yageta M, Masuda M, Tsuboi Y, Iwai M, Kawai T, Murakami S, Ito T, Ito A, Murakami Y.
- Organizer
  The 15^<th> Charles Heidelberger International Symposium on Cancer Research
- Place of Presentation
  タイ国、ピサヌロック市
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] Involvement of a cell adhesion molecule CADM1/TSLC1 in oncogenesis2009
- Author(s)
  Nagata M, Sakurai-Yageta M, Masuda M, Tsuboi Y, Iwai M, Kawai T, Murakami S, Ito T, Ito A, Murakami Y.
- Organizer
  The First Formosan Symposium on Structural Biology of Membrane Proteins and Biomembranes
- Place of Presentation
  台湾、台北市
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] TSLC1 induces lamellipodia formation through activation of Rac in the HTLV-1 infected T cells and the ATL cells.2007
- Author(s)
  Masuda M, Kikuchi S, Maruyama T, Ito A, Murakami Y.
- Organizer
  The 13th International Conference in Human retrovirology. HTLV-1 and related viruses 口演
- Place of Presentation
  箱根
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] TSLC1/CADM1 induces lamellipodia formation through activation of Rac in the HTLV-1 infected T cells and the ATL cells.2007
- Author(s)
  Masuda M, Kikuchi S, Maruyama T, Ito A, Murakami Y.
- Organizer
  日本癌学会口演
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] ヒト家族性腫瘍のモデルとしてのTslc1/Cadm1遺伝子欠損マウスの解析2007
- Author(s)
  山田大介、永田政義、尾鼻孝滋、増田万里、市原博美、増田智子、吉田緑、堤雅弘、北村唯一、村上善則
- Organizer
  第12回家族性腫瘍学会
- Place of Presentation
  高知
- Year and Date
  2007-06-16
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] Involvement of a cell adhesion molecule, TSLC1/CADM1, in lung tumorigenesis.2007
- Author(s)
  Nagata M, Obana T, Sakurai-Yageta M, Tsuboi Y, Yamada D, Masuda M, Ichihara H, Masuda T, Murakami, Y.
- Organizer
  International Sympoisum on Cell Polarity and Future Medicine示説
- Place of Presentation
  葉山
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] 成人T細胞白血病(ATL)において細胞接着分子TSLC1.CADM1が惹起する低分子量G蛋白質Racの活性化とその下流分子の解析2007
- Author(s)
  増田万里、増田智子、伊藤彰彦、大田力、村上善則
- Organizer
  第30回日本分子生物学会年会示説
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] TSLC1 induces lamellipodia formation through activation of Rac in the HTLV-1 infected T cells and the ATL cells.2007
- Author(s)
  Masuda M, Murakami Y, et. al.(5著者中、最終著者)
- Organizer
  The 13th International Conference in Human retrovirology. HTLV-1 and related viruses
- Place of Presentation
  神奈川県箱根町
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] Involvement of a cell adhesion molecule, TSLC1/CADM1, in lung tumorigenesis.2007
- Author(s)
  Nagata M, Obana T, Tsuboi, Y, Sakurai-Yageta, M, Masuda, T, Ichihara, H, Murakami, Y.
- Organizer
  The 14th East Asia Joint Symposium on Biomedical Research シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] TSLC1/CADM1 induces lamellipodia formation through activation of Rac in the HTLV-1 infected T cells and the ATL cells.2007
- Author(s)
  Masuda M, Murakami Y, et. al.(5著者中、最終著者)
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] Male infertility and spontaneous development of lung tumor in mice lacking the tumor suppressor gene, Tslc1/Cadm1.2007
- Author(s)
  Nagata M, Yamada D, Obana T, Masuda M, Ichihara H, Maruyama T, Yoshida M, Tsutsumi M, Murakami Y.
- Organizer
  日本癌学会口演
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] 成人T細胞白血病(ATL)において細胞接着分子TSLC1/CADM1が惹起する低分子量G蛋白質Racの活性化とその下流分子の解析.2007
- Author(s)
  増田万里、村上善則等 (5著者中、最終著者)
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] がん抑制蛋白質TSLC1/CADM1による上皮様形態形成と腫瘍抑制の分子機構の解析2007
- Author(s)
  桜井(八下田)美佳、坪井裕見、増田万里、山田大介、永田政義、尾鼻孝滋、村上善則
- Organizer
  第30回日本分子生物学会年会シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] がん抑制蛋白質TSLC1/CADM1の上皮細胞における結合因子の解析。2007
- Author(s)
  坪井裕見、桜井美佳、増田万里、村上善則(4著者中、最終著者)
- Organizer
  東京大学生命科学研究ネットワークシンポジウム2007
- Place of Presentation
  東京都文京区
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-17015048
[Presentation] Involvement of a Tumor Suppressor TSLC1/CADM1 in Lung Tumorigenesis in Human and the Gene-deficient Mice.2007
- Author(s)
  Murakami Y, Kikuchi S, Yamada D, Nagata M, Obana T, Masuda M, Tsuboi Y, Usui S,, Ichihara H, Maruyama T.
- Organizer
  The 12th World Conference on Lung Cancer 口演
- Place of Presentation
  韓国京城市
- Data Source
  KAKENHI-PROJECT-17015048

1. MURAKAMI Yoshinori (30182108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
2. ITO Akihiko (80273647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. SAKURAI Mika (80508359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
4. 山田哲司

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
5. 小林英介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 弘實透

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 川井章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 吉田朗彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岡本康司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 石本崇胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 林洋光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 三宅慧輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 馬場祥史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 馬場秀夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 原田和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 須田年生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 岩槻政晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 有馬浩太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 内原智幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 本田一文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masuda Mari 増田 万里

MASUDA Mari 増田 万里

増田 万里 マスダ マリ

Research Projects

Research Products

Co-Researchers

Development of a diagnostic platform for precision oncology by applying reverse-phase phosphoprotein array to an analysis of formalin-fixed paraffin-embedded (FFPE) tissuePrincipal Investigator

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Identification of regulatory components of Wnt signaling in beta-catenin and T-cell factor-4 transcriptional complex as therapeutic targets for colorectal cancerPrincipal Investigator

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Development of reverse-phase protein array platform for analyzing tissue samples and identification of biomarkers to guide the use of a TNIK inhibitorPrincipal Investigator

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Molecular understanding and diagnosis of human cancer through the structural, functional and expression analysis of cancer related genes.

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[Book] Biomarkers in Cancer Therapy2019

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[Book] Chapter 10. Biomarkers of Lung Cancer: Liquid Biopsy Comes of Age. Biomarkers in Cancer Therapy.2019

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[Book] Chapter 15. Utility of Reverse-phase Protein Array for Refining Precision Oncology, Reverse-Phase Protein Array, Advances in Experimental Medicine and Biology2019

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[Book] 大腸がんの幹細胞増殖を抑える新規化合物発見から創薬へ2017

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[Book] 大腸がんの幹細胞増殖を抑える新規化合物発見から創薬へ2017

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[Journal Article] Pharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846.2021

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[Journal Article] Direct conversion of osteosarcoma to adipocytes by targeting TNIK2021

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[Journal Article] Whole-exome and RNA sequencing of pulmonary carcinoid reveals chromosomal rearrangements associated with recurrence2020

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[Journal Article] Feasibility of Targeting Traf2-and-Nck-Interacting Kinase in Synovial Sarcoma.2020

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[Journal Article] Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance2020

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Masuda Mari 増田万里

MASUDA Mari 増田万里

増田万里マスダマリ