Sakai Nozomu 酒井望

… Alternative Names

Nozomu Sakai 酒井望

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Researcher Number	70436385
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 助教
Affiliation (based on the past Project Information) *help	2024: 千葉大学, 大学院医学研究院, 助教 2014 – 2023: 千葉大学, 医学部附属病院, 助教 2017: 千葉大学, 医学部附属病院, その他
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator 転移 / 浸潤 / ING5 / 上皮-間葉移行 / Cancer stemness / 細胞遊走能 / 癌幹細胞 / 癌 / KLF / EMT / 転移性肝癌 / 増殖 … More Except Principal Investigator … More EMT / 膵癌 / Pin1 / 大腸癌肝転移 / 大腸癌 / 肝内胆管癌 / STAT3 / 浸潤・転移 / 膵臓外科学 / 転移 / NF-kappaB / 肝細胞癌 / 肝胆膵領域癌 / Fn14 / TWEAK / CRLM / TWEAK/Fn14 axis / ポリコーム群タンパク / YAF2 / 肝転移 / 転移メカニズム / BAP1 / precision medicine / 胆道癌 / 相同組換え修復欠損 / RAD51 / p53 / apoptosis / cell cycle / Tumor suppressor / RYBP / Tspan15 / IRG1 / Notch1 / Tetraspanin15 / CSC-like property / NOTCH1 / ADAM10 / TSPAN15 / Cancer stemness / Wnt-β-cateninシグナル / PD-L1 / 転写因子活性 / Wntシグナル / β-catenin / 癌幹細胞能 / GRIM19 / OLFM4 / LGR5 / 癌進展機構 / 癌進展機序 / 補体因子 / 膵胆道癌 / 腫瘍浸潤リンパ球 / 癌周囲微小環境 / バイオマーカー / 補体 / 加齢 / 肝切除 / 微小循環障害 / NF-kappaB-p65 / 高齢肝 / 肝再生 / 拡大肝切除 / 高齢者 / 癌 / 浸潤 / 癌細胞ー間質相互作用 / Tenascin C / Annexin II / 浸潤、転移 / MET / Epithelial plasticity / 中和抗体 / Metadherin / Prrx1 / 腫瘍細胞浸潤 / 腫瘍細胞増殖 / 胆嚢癌 / ＳＴＡＴ３ / ＮＦ－ｋａｐｐａＢ / Ｐｉｎ１ Less

ING5による大腸癌の進展、転移および化学療法抵抗性に対する抑制的制御機構の解明Principal Investigator
- Principal Investigator
  
  酒井望
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
Construction of Precision Medicine Based on Homologous Recombination Deficiency in Biliary Tract Cancer
- Principal Investigator
  
  藤井康矢
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
Functional analysis of BAP1 in the control of gastrointestinal cancer progression and metastasis.
- Principal Investigator
  
  岡義人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
ポリコームタンパクYAF2による大腸癌の進展、転移、再発における制御機構の解明
- Principal Investigator
  
  佐藤駿介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
大腸癌肝転移のTWEAK/Fn14 axisを介した腫瘍進展メカニズムの解明と新規治療薬の開発
- Principal Investigator
  
  松山尚樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
大腸癌におけるRYBP を介した腫瘍制御機構の解明
- Principal Investigator
  
  森中孝至
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
Novel therapeutic strategy based on IRG1-mediated anti-inflammatory effects in hepato-biliary-pancreatic cancer
- Principal Investigator
  
  Yoshizumi Arihito
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
Development of a new therapy targeting LGR5-induced STAT3 activation in hepato-biliary-pancreatic cancer
- Principal Investigator
  
  Satoshi Kuboki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
Tumor-suppressive role of Smad ubiquitination regulatory factor 2 in patients with colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Sakai Nozomu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
The elucidation of mechanism underlying pancreatic cancer progression by complement and secreted proteins in tumor microenvironment.
- Principal Investigator
  
  Takano Shigetsugu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Chiba University
A new approach for avoiding age-related risks after extended hepatectomy by targeting Pin1.
- Principal Investigator
  
  Kuboki Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Elucidation of the role of KLF5, 17 in metastatic cascade of gastrointestinal cancerPrincipal Investigator
- Principal Investigator
  
  Nozomu Sakai
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Expression of annexin II and stromal tenascin C promotes epithelial to mesenchymal transition and correlates with distant metastasis in pancreatic cancer
- Principal Investigator
  
  Takano Shigetsugu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Elucidation of molecular mechanism for pancreato-biliary cancer progression through EMT plasticity
- Principal Investigator
  
  Takano Shigetsugu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Inflammation-associated NF-kappaB activation promotes tumor progression in hepato-biliary-pancreatic cancer.
- Principal Investigator
  
  Kuboki Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] RYBP contributes to improved prognosis in colorectal cancer via regulation of cell cycle, apoptosis and oxaliplatin sensitivity2023
- Author(s)
  Morinaka Takashi、Sakai Nozomu、Takayashiki Tsukasa、Kuboki Satoshi、Takano Shigetsugu、Ohira Gaku、Matsubara Hisahiro、Ohtsuka Masayuki
- Journal Title
  
  International Journal of Oncology
  
  Volume: 63 Issue: 5
- DOI
  10.3892/ijo.2023.5568
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08889
[Journal Article] Tumor-suppressive role of Smad ubiquitination regulatory factor 2 in patients with colorectal cancer2022
- Author(s)
  Sato N, Sakai N, Furukawa K, Takayashiki T, Kuboki S, Takano S, Ohira G, Miyauchi H, Matsubara H, Ohtsuka M.
- Journal Title
  
  Scientific reports
  
  Volume: 12 Issue: 1 Pages: 5495-5495
- DOI
  10.1038/s41598-022-09390-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09164, KAKENHI-PROJECT-20K09049, KAKENHI-PROJECT-20K17640
[Journal Article] Differential effects of KRAS mutational status on long-term survival according to the timing of colorectal liver metastases.2021
- Author(s)
  Sakai N, Furukawa K, Takayashiki T, Kuboki S, Takano S, Ohtsuka M.
- Journal Title
  
  BMC Cancer
  
  Volume: 21 Issue: 1 Pages: 412-412
- DOI
  10.1186/s12885-021-08144-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03725
[Journal Article] Simultaneous brain and lung metastases of pancreatic ductal adenocarcinoma after curative pancreatectomy: a case report and literature review2021
- Author(s)
  Oka Yoshito、Takano Shigetsugu、Kouchi Yusuke、Furukawa Katsunori、Takayashiki Tsukasa、Kuboki Satoshi、Suzuki Daisuke、Sakai Nozomu、Kagawa Shingo、Hosokawa Isamu、Mishima Takashi、Konishi Takanori、Kishimoto Takashi、Ohtsuka Masayuki
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 21 Issue: 1 Pages: 9-9
- DOI
  10.1186/s12876-020-01587-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17639, KAKENHI-PROJECT-19H03725
[Journal Article] Outcome of interventional radiology for delayed postoperative hemorrhage in hepatobiliary and pancreatic surgery2020
- Author(s)
  Sakai Nozomu、Yoshitomi Hideyuki、Furukawa Katsunori、Takayashiki Tsukasa、Kuboki Satoshi、Takano Shigetsugu、Suzuki Daisuke、Kagawa Shingo、Mishima Takashi、Nakadai Eri、Ohtsuka Masayuki
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 35 Issue: 12 Pages: 2264-2272
- DOI
  10.1111/jgh.15140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-19H03725
[Journal Article] Needle tract seeding recurrence of pancreatic cancer in the gastric wall with paragastric lymph node metastasis after endoscopic ultrasound-guided fine needle aspiration followed by pancreatectomy: a case report and literature review.2020
- Author(s)
  Sato N, Takano S, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Suzuki D, Sakai N, Kagawa S, Mishima T, Nakadai E, Mikata R, Kato N, Ohtsuka M.
- Journal Title
  
  BMC Gastroenterol.
  
  Volume: 20 Pages: 13-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03725
[Journal Article] Long-term outcomes and significance of preoperative lymphocyte-to-monocyte ratio as a prognostic indicator in patients with invasive pancreatic neoplasms after repeat pancreatectomy2020
- Author(s)
  Takano Shigetsugu、Yoshitomi Hideyuki、Kagawa Shingo、Furukawa Katsunori、Takayashiki Tsukasa、Kuboki Satoshi、Suzuki Daisuke、Sakai Nozomu、Mishima Takashi、Nakadai Eri、Miyazaki Masaru、Ohtsuka Masayuki
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 111-111
- DOI
  10.1186/s12885-020-6602-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08671, KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-17H04287, KAKENHI-PROJECT-19H03725
[Journal Article] Needle tract seeding recurrence of pancreatic cancer in the gastric wall with paragastric lymph node metastasis after endoscopic ultrasound-guided fine needle aspiration followed by pancreatectomy: a case report and literature review2020
- Author(s)
  Sato Nami、Takano Shigetsugu、Yoshitomi Hideyuki、Furukawa Katsunori、Takayashiki Tsukasa、Kuboki Satoshi、Suzuki Daisuke、Sakai Nozomu、Kagawa Shingo、Mishima Takashi、Nakadai Eri、Mikata Rintaro、Kato Naoya、Ohtsuka Masayuki
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 20 Issue: 1 Pages: 13-13
- DOI
  10.1186/s12876-020-1159-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-19H03725
[Journal Article] High expression of Kruppel‐like factor 5 is associated with poor prognosis in patients with colorectal cancer2020
- Author(s)
  Takagi Yutaka、Sakai Nozomu、Yoshitomi Hideyuki、Furukawa Katsunori、Takayashiki Tsukasa、Kuboki Satoshi、Takano Shigetsugu、Suzuki Daisuke、Kagawa Shingo、Mishima Takashi、Nakadai Eri、Miyauchi Hideaki、Matsubara Hisahiro、Ohtsuka Masayuki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 6 Pages: 2078-2092
- DOI
  10.1111/cas.14411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-19H03725
[Journal Article] 誌上ディベート　肝胆膵外科におけるcontroversial surgery 3. 両葉多発大腸癌肝転移に対する肝切除 2）Major hepatectomyの立場から2019
- Author(s)
  酒井望、吉富秀幸、古川勝規、高屋敷吏、久保木知、高野重紹、鈴木大亮、賀川真吾野島広之、三島敬、中台英里、大塚将之
- Journal Title
  
  手術
  
  Volume: 73 Pages: 290-297
- Data Source
  KAKENHI-PROJECT-16K10564
[Journal Article] Is hepatic artery coil embolization useful in distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic cancer?2019
- Author(s)
  Ueda A, Sakai N, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Kagawa S, Mishima T, Nakadai E, Miyazaki M, Ohtsuka M.
- Journal Title
  
  World J Surg Oncol. 124
  
  Volume: 17 Issue: 1 Pages: 124-124
- DOI
  10.1186/s12957-019-1667-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-17H04287, KAKENHI-PROJECT-19H03725
[Journal Article] Successful treatment of a locally advanced unresectable pancreatic cancer patient with interstitial pneumonitis by conversion surgery following gemcitabine plus nab-paclitaxel chemotherapy: A case report.2019
- Author(s)
  Yokota T, Takano S, Yoshitomi H, Kagawa S, Furukawa K, Takayashiki T, Kuboki S, Suzuki D, Sakai N, Nojima H, Mishima T, Nakadai E, Ohtsuka M.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 10 Pages: 419-424
- DOI
  10.3892/mco.2019.1807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-19H03725, KAKENHI-PROJECT-18K15040
[Journal Article] Feasibility and safety of distal pancreatectomy with en bloc celiac axis resection (DP-CAR) combined with neoadjuvant therapy for borderline resectable and unresectable pancreatic body/tail cancer.2019
- Author(s)
  Yoshitomi H, Sakai N, Kagawa S, Takano S, Ueda A, Kato A, Furukawa K, Takayashiki T, Kuboki S, Miyzaki M, Ohtsuka M
- Journal Title
  
  Langenbecks Arch Surg.
  
  Volume: In press Issue: 4 Pages: 1-8
- DOI
  10.1007/s00423-019-01775-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10661, KAKENHI-PROJECT-18K08671, KAKENHI-PROJECT-17H04287, KAKENHI-PROJECT-19H03725
[Journal Article] Conversion surgery with gemcitabine plus nab-paclitaxel for locally advanced unresectable pancreatic cancer: A case report.2018
- Author(s)
  Okura R, Takano S, Yokota T, Yoshitomi H, Kagawa S, Furukawa K, Takayashiki T, Kuboki S, Suzuki D, Sakai N, Nojima H, Mishima T, Miyazaki M, Ohtsuka M.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 9 Pages: 389-393
- DOI
  10.3892/mco.2018.1688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10661, KAKENHI-PROJECT-17H04287, KAKENHI-PROJECT-16K15607
[Journal Article] Novel treatment strategy with radiofrequency ablation and surgery for pregnant patients with hepatocellular carcinoma: a case report.2018
- Author(s)
  Matsuo M, Furukawa K, Shimizu H, Yoshitomi H, Takayashiki T, Kuboki S, Takano S, Suzuki D, Sakai N, Kagawa S, Nojima H, Ohsuka M.
- Journal Title
  
  Surg Case Rep.
  
  Volume: 4 Issue: 1 Pages: 43-43
- DOI
  10.1186/s40792-018-0434-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10661, KAKENHI-PROJECT-18K15040
[Journal Article] 特集外科手術器具の理論と使用法 Ⅷ.その他の手術器具･材料深部生検に用いる超音波プローブと生検針の種類と使用法2017
- Author(s)
  高屋敷吏、三島敬、大塚将之、吉富秀幸、古川勝規、久保木知、高野重紹、鈴木大亮、酒井望、賀川真吾、野島広之
- Journal Title
  
  外科
  
  Volume: 79 Issue: 12 Pages: 1312-1315
- DOI
  10.15106/j_geka79_1312
- ISSN
  0016-593X, 2432-9428
- Year and Date
  2017-11-25
- Data Source
  KAKENHI-PROJECT-16K10564
[Journal Article] Postoperative serious complication and emergency treatment:liver abscess2017
- Author(s)
  高屋敷吏、野島広之、細川勇、大塚将之、清水宏明、吉富秀幸、古川勝規、久保木知、高野重紹、鈴木大亮、酒井望、賀川真吾
- Journal Title
  
  臨床外科
  
  Volume: 72 Issue: 6 Pages: 721-724
- DOI
  10.11477/mf.1407211647
- ISSN
  0386-9857, 1882-1278
- Year and Date
  2017-06-20
- Data Source
  KAKENHI-PROJECT-16K10564
[Journal Article] 胆膵進行癌に対する外科治療戦略胆道胆道癌に対する術前化学療法　進行胆道癌に対するconversion surgeryをめざした術前化学療法2017
- Author(s)
  久保木知、三島敬、大塚将之、吉富秀幸、古川勝規、高屋敷吏、高野重紹、鈴木大亮、酒井望、賀川真吾、野島広之
- Journal Title
  
  外科
  
  Volume: 79 Issue: 8 Pages: 738-741
- DOI
  10.15106/J00393.2017324288
- ISSN
  0016-593X, 2432-9428
- Year and Date
  2017-08-01
- Data Source
  KAKENHI-PROJECT-16K10564
[Journal Article] 特集最新の胆道癌診療トピックス-新たな治療戦略の可能性を探る手術手技肝動脈浸潤を伴う胆道癌の切除-右肝動脈浸潤を伴う肝門部領域胆管癌に対する肝左3区域切除術2017
- Author(s)
  久保木知、野島広之、三島敬、宮崎勝、大塚将之、清水宏明、吉富秀幸、古川勝規、高屋敷吏、高野重紹、鈴木大亮、酒井望、賀川真吾
- Journal Title
  
  臨床外科
  
  Volume: 72 Issue: 13 Pages: 1462-1465
- DOI
  10.11477/mf.1407211880
- ISSN
  0386-9857, 1882-1278
- Year and Date
  2017-12-20
- Data Source
  KAKENHI-PROJECT-16K10564
[Journal Article] FOCUS 血行再建時の静脈グラフト選択のポイント-左腎静脈グラフトによる門脈再建術2017
- Author(s)
  高野重紹、野島広之、宮崎勝、大塚将之、吉富秀幸、清水宏明、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、賀川真吾
- Journal Title
  
  臨床外科
  
  Volume: 72 Issue: 2 Pages: 204-207
- DOI
  10.11477/mf.1407211518
- ISSN
  0386-9857, 1882-1278
- Year and Date
  2017-02-20
- Data Source
  KAKENHI-PROJECT-16K10564
[Journal Article] An adequate technique of hepaticojejunostomy for reducing postoperative complications2017
- Author(s)
  久保木知、野島広之、細川勇、宮崎勝、大塚将之、清水宏明、吉富秀幸、古川勝規、高屋敷吏、高野重紹、鈴木大亮、酒井望、賀川真吾
- Journal Title
  
  臨床外科
  
  Volume: 72 Issue: 4 Pages: 479-481
- DOI
  10.11477/mf.1407211591
- ISSN
  0386-9857, 1882-1278
- Year and Date
  2017-04-20
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 肝内胆管癌におけるFAK/phospho-FAKの役割2023
- Author(s)
  髙柳　良介、久保木　知、古川　勝規、高屋敷　吏、高野　重紹、鈴木　大亮、酒井　望、細川　勇、三島　敬、小西　孝宜、西野　仁恵、仲田　真一郎、大塚　将之
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09049
[Presentation] Tspan15は肝内胆管癌の予後不良因子であり, 化学療法抵抗性を誘導する2023
- Author(s)
  吉住有人, 久保木知, 高屋敷吏, 高野重紹, 鈴木大亮, 酒井望,細川勇, 三島敬, 小西孝宜, 西野仁恵, 仲田真一郎, 大塚将之
- Organizer
  第21回消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-21K08792
[Presentation] 肝胆道癌において炎症性シグナルを介した転写因子活性亢進は浸潤・転移能を高めることにより腫瘍進展を促進する2022
- Author(s)
  久保木　知、古川　勝規、高屋敷　吏、高野　重紹、鈴木　大亮、酒井　望、細川　勇、三島　敬、小西　孝宜、西野　仁恵、仲田　真一郎、大塚　将之
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09049
[Presentation] 肝胆道癌において炎症性シグナルを介した転写因子活性亢進は浸潤・転移能を高めることにより腫瘍進展を促進する2022
- Author(s)
  久保木知, 古川勝規, 高屋敷吏, 高野重紹, 鈴木大亮, 酒井望, 細川勇, 三島敬, 小西孝宜, 西野仁恵, 大塚将之
- Organizer
  第122回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09049
[Presentation] フコシル化C4BPAの膵癌血清バイオマーカーとしての意義2021
- Author(s)
  高野重紹、曽川一幸、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、細川勇、三島敬、大塚将之
- Organizer
  第30回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] 宿主免疫応答と補体因子による膵癌進展機構の解明と治療への応用2021
- Author(s)
  高野重紹、佐々木亘亮、島崎怜理、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、細川勇、三島敬、小西孝宜、大塚将之
- Organizer
  第52回日本膵臓学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] 膵癌周囲微小環境での補体因子が及ぼす膵癌進展機構の解明2021
- Author(s)
  高野重紹、島崎怜理、佐々木亘亮、吉富秀幸、賀川真吾、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、三島敬、大塚将之
- Organizer
  第51回日本膵臓学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] 進行胆嚢癌におけるPD-L1発現の臨床的意義2021
- Author(s)
  佐藤豊, 久保木知, 古川勝規, 高屋敷吏, 高野重紹, 鈴木大亮, 酒井望, 賀川真吾, 細川勇, 三島敬, 小西孝宜, 大塚将之
- Organizer
  第121回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09049
[Presentation] 局所進行膵癌に対する術前GSおよびGnP療法による長期予後および転移再発形式の検討2020
- Author(s)
  高野重紹、吉富秀幸、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、賀川真吾、三島敬、中台英里、大塚将之
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] LGR5-WntシグナルはSTAT3活性亢進を介して肝内胆管癌のstemness及びEMTを促進することにより腫瘍悪性度を高める2020
- Author(s)
  川﨑圭史, 久保木知, 吉富秀幸, 古川勝規, 高屋敷吏, 高野重紹, 鈴木大亮, 酒井望, 賀川真吾, 三島敬, 中台英里, 小西孝宣, 大塚将之
- Organizer
  第120回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09049
[Presentation] 膵癌微小環境での補体因子が及ぼす転移機構の解明2020
- Author(s)
  高野重紹、島崎怜理、佐藤守、高田護、吉富秀幸、賀川真吾、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、三島敬、大塚将之
- Organizer
  第29回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] The impact of Lymphocyte-to-monocyte ratio (LMR) in patients with borderline resectable pancreatic head cancer after curative surgery.2019
- Author(s)
  Yoji Miyahara, Shigetsugu Takano, Hideyuki Yoshitomi, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Takashi Mishima, Eri Nakadai, Masayuki Ohtsuka
- Organizer
  AACR special conference Pancreatic Cancer: Advances in Science and Clinical Care
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] The clinical impact and analysis for neoadjuvant chemotherapy against borderline resectable pancreatic cancer: gemcitabine plus S-1 vs gemcitabine plus nab-paclitaxel.2019
- Author(s)
  Shigetsugu Takano, Hideyuki Yoshitomi, Shingo Kagawa, Furukawa Katsunori, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Takashi Mishima, Eri Nakadai, Masayuki Ohtsuka
- Organizer
  AACR special conference Pancreatic Cancer: Advances in Science and Clinical Care
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] C4BPA identified as a novel biomarker is associated with favorable outcome of patients with pancreatic cancer.2019
- Author(s)
  Kosuke Sasaki, Shigetsugu Takano, Hideyuki Yoshitomi, Kazuyuki Sogawa, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Takashi Mishima, Eri Nakadai, Masayuki Ohtsuka
- Organizer
  AACR special conference Pancreatic Cancer: Advances in Science and Clinical Care
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03725
[Presentation] Clinical outcome of ALPPS -A Single Institute Experience-2018
- Author(s)
  Nozomu Sakai, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Shingo Kagawa, Hiroyuki Nojima Takashi Mishima, Masaru Miyazaki, Masayuki Ohtsuka
- Organizer
  13th IHPBA World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 大腸癌肝転移に対するConversion surgeryの治療成績2018
- Author(s)
  酒井望、吉富秀幸、古川勝規、高屋敷吏、久保木知、高野重紹、鈴木大亮賀川真吾、野島広之、三島敬、中台英里、大塚将之
- Organizer
  第80回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 大腸癌多発肝転移に対する治療成績2018
- Author(s)
  酒井望、吉富秀幸、古川勝規、高屋敷吏、久保木知、高野重紹、鈴木大亮、賀川真吾野島広之、三島敬、大塚将之
- Organizer
  第54回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] Prognostic impact of preoperative chemotherapy for resectable colorectal liver metastases2018
- Author(s)
  Nozomu Sakai, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki Shigetsugu Takano, Daisuke Suzuki, Shingo Kagawa, Hiroyuki Nojima、Takashi Mishima Masayuki Ohtsuka
- Organizer
  第30回日本肝胆膵外科学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 大腸癌肝肺転移に対する切除成績2018
- Author(s)
  酒井望、吉富秀幸、古川勝規、高屋敷吏、久保木知、高野重紹、鈴木大亮、賀川真吾野島広之、三島敬、大塚将之
- Organizer
  第26回日本消化器関連学会週間 (JDDW)
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] Treatment strategy for multiple colorectal liver metastases2018
- Author(s)
  Nozomu Sakai, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Shingo Kagawa, Hiroyuki Nojima Masayuki Ohtsuka
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] Strategy to overcome insufficient future liver remnant　our experience of ALPPS-2018
- Author(s)
  Nozomu Sakai, Masayuki Ohtsuka
- Organizer
  第26回日本消化器関連学会週間 (JDDW)
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 大腸癌多発肝転移に対する治療戦略2018
- Author(s)
  酒井望、吉富秀幸、古川勝規、高屋敷吏、久保木知、高野重紹、鈴木大亮、賀川真吾野島広之、三島敬、大塚将之
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 術後再発からみた大腸癌肝転移に対するconversion surgeryの治療成績2017
- Author(s)
  酒井望, 吉富秀幸, 古川勝規, 高屋敷吏, 久保木知, 高野重紹, 鈴木大亮, 賀川真吾, 野島広之, 三島敬, 大塚将之
- Organizer
  日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] Annexin II発現による抗癌剤耐性、および癌-間質細胞間相互作用による浸潤転移機構の解明2017
- Author(s)
  米浦直子、高野重紹、賀川真吾、吉富秀幸、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井　望、野島広之、大塚将之
- Organizer
  日本がん転移学会
- Data Source
  KAKENHI-PROJECT-16K15607
[Presentation] 大腸癌肝転移に対する治療戦略大腸癌肝転移切除後再発に対するrepeat resectionの意義2017
- Author(s)
  酒井望, 清水宏明, 吉富秀幸, 古川勝規, 高屋敷吏, 久保木知, 高野重紹, 鈴木大亮, 宮崎勝, 大塚将之
- Organizer
  日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] 高齢胆道癌患者に対する拡大肝切除術を安全に施行するための至適残肝率の再考2017
- Author(s)
  久保木　知、渡邉　善寛、野島　広之、吉富　秀幸、古川　勝規、高屋敷　吏、高野　重紹、鈴木　大亮、酒井　望、賀川　真吾、三島　敬、宮崎　勝、大塚　将之
- Organizer
  第79回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10661
[Presentation] 大腸癌肝転移切除後の肝再発、肝外再発に対する外科治療成績の検討2017
- Author(s)
  酒井望、清水宏明, 吉富秀幸, 古川勝規, 高屋敷吏, 高野重紹, 久保木知, 鈴木大亮, 賀川真吾, 野島広之, 宮崎勝, 大塚将之
- Organizer
  日本外科学会定期学術集会抄録集
- Data Source
  KAKENHI-PROJECT-16K10564
[Presentation] Identification of a novel serum biomarker for pancreatic cancer, C4b-binding protein alpha-chain (C4BPA) by quantitative proteomic analysis using tandem mass tag2017
- Author(s)
  高野重紹、曽川一幸、吉富秀幸、清水宏明、古川勝規、高屋敷　吏、久保木　知、鈴木大亮、酒井　望、賀川真吾、野島広之、野村文夫、宮崎　勝、大塚将之
- Organizer
  日本外科学会
- Data Source
  KAKENHI-PROJECT-15H04925
[Presentation] 膵癌早期診断バイオマーカーとしての血清C4BPA値の意義2017
- Author(s)
  高野重紹、曽川一幸、吉富秀幸、清水宏明、古川勝規、高屋敷　吏、久保木　知、鈴木大亮、酒井　望、賀川真吾、野島広之、野村文夫、宮崎　勝、大塚将之
- Organizer
  日本膵臓学会
- Data Source
  KAKENHI-PROJECT-15H04925
[Presentation] 残肝容量不足時のshare stress増強に伴う類洞内皮障害軽減に対する脾摘の意義に関する基礎的研究2017
- Author(s)
  久保木　知、清水　宏明、吉富　秀幸、古川　勝規、高屋敷　吏、高野　重紹、鈴木　大亮、酒井　望、賀川　真吾、野島　広之、宮崎　勝、大塚　将之
- Organizer
  第35回日本肝移植研究会
- Data Source
  KAKENHI-PROJECT-17K10661
[Presentation] Annexin II発現における膵癌バイオマーカーの臨床学的意義2016
- Author(s)
  高野重紹、吉富秀幸、賀川真吾、清水宏明、大塚将之、加藤厚、古川勝規、高屋敷吏、久保木知、鈴木大亮、酒井望、野島広之、宮崎勝
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場/リーガロイヤルホテル大阪（大阪府大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-16K15607
[Presentation] 浸潤性膵管癌の悪性度評価におけるPin1発現の有用性および治療標的因子としての可能性の検討2016
- Author(s)
  久保木　知、鈴木　崇之、野島　広之、清水　宏明、大塚　将之、加藤　厚、吉富　秀幸、古川　勝規、高屋敷　吏、高野　重紹、鈴木　大亮、酒井　望、賀川　真吾、宮崎　勝
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26462036
[Presentation] 肝細胞癌におけるPin1を介した腫瘍進展機序に基づいた系統的肝切除の有用性の検討2016
- Author(s)
  久保木　知、篠田　公男、野島　広之、清水　宏明、大塚　将之、加藤　厚、吉富　秀幸、古川　勝規、高屋敷　吏、高野　重紹、鈴木　大亮、酒井　望、賀川　真吾、宮崎　勝
- Organizer
  第25回日本癌病態治療研究会
- Place of Presentation
  三井ガーデンホテル(千葉県千葉市）
- Year and Date
  2016-06-08
- Data Source
  KAKENHI-PROJECT-26462036
[Presentation] Regulation of STAT3 activity by controlling the functions of Pin1 or DRAC effectively inhibits tumor proliferation/invasiveness in human pancreatic ductal adenocarcinoma2016
- Author(s)
  Satoshi Kuboki, Shintaro Maeda, Takayuki Suzuki, Hiroyuki Nojima, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Shigetsugu Takano, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
- Organizer
  第47回日本膵臓学会大会・第20回国際膵臓学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462036
[Presentation] Prrx1 isoformとgemcitabine耐性及びCD133との関連2015
- Author(s)
  高野重紹、吉富秀幸、清水宏明、大塚将之、加藤厚、古川勝規、高屋敷吏、久保木　知、鈴木大亮、酒井　望、賀川真吾、野島広之、宮崎　勝
- Organizer
  第10回膵癌術前治療研究会
- Place of Presentation
  大宮ソニックシティ（埼玉・大宮）
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-15H04925
[Presentation] Prrx1を標的とした膵癌の個別化分子治療への応用2015
- Author(s)
  高野重紹、吉富秀幸、清水宏明、大塚将之、加藤厚、古川勝規、高屋敷吏、久保木知、岡村大樹、鈴木大亮、酒井望、賀川真吾、Anil K Rustgi、宮崎勝
- Organizer
  第46回日本膵臓学会大会
- Place of Presentation
  名古屋国際会議場（名古屋・名古屋）
- Year and Date
  2015-06-19
- Data Source
  KAKENHI-PROJECT-15H04925

1. 大塚将之 (90334185)

# of Collaborated Projects: 11 results

# of Collaborated Products: 28 results
2. Kuboki Satoshi (50571410)

# of Collaborated Projects: 8 results

# of Collaborated Products: 32 results
3. 高屋敷吏 (30456024)

# of Collaborated Projects: 7 results

# of Collaborated Products: 22 results
4. Takano Shigetsugu (20436380)

# of Collaborated Projects: 6 results

# of Collaborated Products: 34 results
5. 賀川真吾 (90507302)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
6. 宮崎勝 (70166156)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
7. 吉富秀幸 (60375631)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
8. 小西孝宜 (80865882)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
9. 鈴木大亮 (90422229)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
10. 佐藤守 (20401002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 細川勇 (60623676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. 西野仁惠 (10769813)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. Yoshizumi Arihito (90895856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 清水宏明 (80272318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 野島広之 (10507320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. 古川勝規 (00400987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 森中孝至 (70895854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 三島敬 (70802560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. 藤井康矢 (90990945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 鈴木謙介 (60769793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 岡義人 (50925287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 佐藤駿介 (30971741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 松山尚樹 (20971724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sakai Nozomu 酒井 望

Nozomu Sakai 酒井 望

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ING5による大腸癌の進展、転移および化学療法抵抗性に対する抑制的制御機構の解明Principal Investigator

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Tumor-suppressive role of Smad ubiquitination regulatory factor 2 in patients with colorectal cancerPrincipal Investigator

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Elucidation of the role of KLF5, 17 in metastatic cascade of gastrointestinal cancerPrincipal Investigator

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Sakai Nozomu 酒井望

Nozomu Sakai 酒井望

[Journal Article] 誌上ディベート　肝胆膵外科におけるcontroversial surgery 3. 両葉多発大腸癌肝転移に対する肝切除 2）Major hepatectomyの立場から2019