Kawasaki Hiroshi 川崎洋

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KAWASAKI Hiroshi 川崎洋

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Researcher Number	70445344
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 国立研究開発法人理化学研究所, 生命医科学研究センター, 上級研究員 2016: 慶應義塾大学, 医学部(信濃町), 共同研究員 2015: 慶應義塾大学, 医学部, 研究員 2014 – 2015: 慶應義塾大学, 医学部, 特任助教 2013: 慶應義塾大学, 医学部, 助教 2012: 慶應義塾大学, 医学部, 研究員 2009 – 2010: Keio University, 医学部, 研究員(非常勤)
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Basic Section 53050:Dermatology-related / Respiratory organ internal medicine
Keywords	Principal Investigator アトピー性皮膚炎 / 皮膚バリア / フィラグリン / Deep phenotype / スキンケア / 皮膚細菌叢 / 乾燥環境 / 皮膚炎症・再生学 Except Principal Investigator 代謝・内分泌 / 多臓器円環 … More / 内分泌 / 代謝 / アトピー性皮膚炎 / 免疫寛容の誘導 / 免疫寛容 Less

Mechanistic investigation of atopic dermatitis associated with abnormality in endocrine and metabolism systems
- Principal Investigator
  
  宮井智浩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Institute of Physical and Chemical Research
Deep phenotype study for precision skin care in atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  Kawasaki Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Institute of Physical and Chemical Research
Clarification of the pathogenesis of atopic disease by using filaggrin deficient mice in dry environmentPrincipal Investigator
- Principal Investigator
  
  Kawasaki Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Induction of tolerance in the airways by extracellular ATP
- Principal Investigator
  
  Suzuki Yusuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kitasato University
  Keio University
Analysis of filaggrin-null mice in dry environment to understand the pathogenic mechanism of atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Development of a New Model for Atopic Dermatitis Using Filaggrin Mutant MicePrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Keio University

All 2023 2022 2021 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] Loss-of-function mutations within the filaggrin gene predispose to atopic dermatitis. 412011
- Author(s)
  Kawasaki H, Kubo A, Sasaki T, Amagai M.
- Publisher
  KARGER. Curr Probl Dermatol.(in press)
- Data Source
  KAKENHI-PROJECT-21791095
[Journal Article] Multifaceted analysis of cross-tissue transcriptomes reveals phenotype-endotype associations in atopic dermatitis2023
- Author(s)
  Sekita A, Kawasaki H, Fukushima-Nomura A, Yashiro K, Tanese K, Toshima S, Ashizaki K, Miyai T, Yazaki J Kobayashi A, Namba S, Naito T, Wang Q S., Kawakami E, Seita J, Ohara O, Sakurada K, Okada Y, Amagai M, Koseki H
- Journal Title
  
  Nature Communications
  
  Volume: 14(1) Issue: 1 Pages: 6133-6133
- DOI
  10.1038/s41467-023-41857-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08420, KAKENHI-PROJECT-22H04994, KAKENHI-PROJECT-22H00476
[Journal Article] Comprehensive Genomic Characterization of Staphylococcus aureus Isolated from Atopic Dermatitis Patients in Japan: Correlations with Disease Severity, Eruption Type, and Anatomical Site2023
- Author(s)
  Obata Shoko、Hisatsune Junzo、Kawasaki Hiroshi、Fukushima-Nomura Ayano、Ebihara Tamotsu、Arai Chika、Masuda Kanako、Kutsuno Shoko、Iwao Yasuhisa、Sugai Motoyuki、Amagai Masayuki、Tanese Keiji
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 4 Pages: 0523922-0523922
- DOI
  10.1128/spectrum.05239-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08338, KAKENHI-PROJECT-22H04994
[Journal Article] Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssinus extract.2010
- Author(s)
  Moniaga CS, Egawa G, Kawasaki H, Hara-Chikuma M, Honda T, Tanizaki H, Nakajima S, Otsuka A, Matsuoka H, Kubo A, Sakabe J, Tokura Y, Miyachi Y, Amagai M, Kabashima K
- Journal Title
  
  Am J Pathol 176(5)
  
  Pages: 2385-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791095
[Journal Article] SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing.
- Author(s)
  Matsui T, Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Tanahashi S, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M
- Journal Title
  
  EMBO Mol Med. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] アトピー性皮膚炎診療や発症予防への応用を目指した皮膚細菌叢解析2023
- Author(s)
  川崎　洋
- Organizer
  第72回日本アレルギー学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08338
[Presentation] The thirteen bacterial species inversely correlated with disease activities of atopic dermatitis in human showed a biotherapeutic potential based on their suppressive effects in mice.2022
- Author(s)
  Kawasaki H, Masuda K, Isayama J, Aoto Y, Obata S, Fukushima-Nomura A, Ito Y, Tanese K, Kawakami E, Amagai M.
- Organizer
  The 51th Annual Meeting of European Society for Dermatological Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08338
[Presentation] Microdissection-based spatial transcriptomics unraveled orchestrated epidermal-dermal interactions in atopic dermatitis2022
- Author(s)
  Tomohiro Miyai, Hiroshi Kawasaki, Masahito Hosokawa, Hiroko Matsunaga, Ayano Fukushima-Nomura, Aiko Sekita, Masayuki Amagai, Haruko Takeyama, Haruhiko Koseki
- Organizer
  2022 ESDR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08420
[Presentation] 皮膚細菌叢解析知見を臨床応用するためのDeep phenotype研究2022
- Author(s)
  川崎洋
- Organizer
  第121回日本皮膚科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08338
[Presentation] Deep-phenotype study focusing on the diversity of skin characteristics in atopic dermatitis2022
- Author(s)
  Kawasaki H
- Organizer
  WAO & BSACI 2022 UK conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08338
[Presentation] アトピー性皮膚炎のスキンケアと治療2021
- Author(s)
  川崎洋
- Organizer
  第8回総合アレルギー講習会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08338
[Presentation] アトピー性皮膚炎診療に皮膚バリア知見を応用する2021
- Author(s)
  川崎洋
- Organizer
  第85回日本皮膚科学会東京支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08338
[Presentation] フィラグリン欠損マウスの角層バリア機能破綻に対する乾燥環境因子の関与2014
- Author(s)
  川崎洋, 久保亮治, 平野尚茂, 山田健人, 天谷雅行
- Organizer
  第42回臨床免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26461702
[Presentation] Filaggrin-null mice exhibit impaired stratum corneum barrier and enhanced percutaneous immune responses2013
- Author(s)
  Kawasaki H
- Organizer
  the Asian Society for Pigment Cell Research and the Australasian Society for Dermatology Research conference 2013
- Place of Presentation
  Sydney, Australia
- Year and Date
  2013-05-19
- Data Source
  KAKENHI-PROJECT-24791176
[Presentation] Exacerbation of the skin barrier function of filaggrin-null mice in dry environment2013
- Author(s)
  Kawasaki H
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張
- Year and Date
  2013-12-13
- Data Source
  KAKENHI-PROJECT-24791176
[Presentation] Filaggrin-null mice exhibit altered skin barrier formation and enhanced percutaneous immune responses.2010
- Author(s)
  川崎洋
- Organizer
  The 35^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  和歌山県民文化会館(和歌山県)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin Knockout Mice as a Tool for Understanding the Pathogenesis of Atopic Dermatitis.2010
- Author(s)
  Kawasaki H
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan.
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin knockout mice as a tool for understanding percutaneous antigen exposure in barrier-disrupted skin.2010
- Author(s)
  Kawasaki H
- Organizer
  the 40^<th> Annual Meeting of European Society for Dermatological Research
- Place of Presentation
  Helsinki, Finland.
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin Knockout Mice as a Tool for Understanding the Pathogenesis of Atopic Dermatitis.2010
- Author(s)
  川崎洋
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸ポートピアホテル、神戸国際展示場(兵庫県)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin knockout mice as a tool for understanding percutaneous antigen exposure in barrier-disrupted skin.2010
- Author(s)
  川崎洋
- Organizer
  The 40^<th> Annual Meeting of European Society for Dermatological Research
- Place of Presentation
  Helsinki (Finland)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin-null mice exhibit altered skin barrier formation and enhanced percutaneousi mmune responses.2010
- Author(s)
  Kawasaki H
- Organizer
  The 35^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Wakayama, Japan.
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin Knocout Mice as a Tool for Understanding the Pathogenesis of Atopic Dermatitis Filaggrin Knocout Mice as a Tool for Understanding the Pathogenesis of Atopic Dermatitis.2009
- Author(s)
  川崎洋
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Filaggrin Knocout Mice as a Tool for Understanding the Pathogenesis of Atopic Dermatitis Filaggrin Knocout Mice as a Tool for Understanding the Pathogenesis of Atopic Dermatitis.2009
- Author(s)
  川崎洋
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] アトピー性皮膚炎病態解明のためのフィラグリン欠失マウスの作製.2009
- Author(s)
  川崎洋
- Organizer
  第16回分子皮膚科学フォーラム
- Place of Presentation
  札幌
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] アトピー性皮膚炎病態解明のためのフィラグリン欠失マウスの作製2009
- Author(s)
  川崎洋
- Organizer
  第16回分子皮膚科学フォーラム
- Place of Presentation
  札幌グランドホテル(北海道)
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21791095
[Presentation] Exacerbation of the skin barrier function of filaggrin-null mice in dry environment.
- Author(s)
  Kawasaki H, Kubo A, Hirano T, Amagai M
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24791176
[Presentation] Filaggrin-null mice exhibit impaired stratum corneum barrier and enhanced percutaneous immune responses.
- Author(s)
  Kawasaki H, Nagao K, Kubo A, Hata T, Mizuno H, Yamada T, Amagai M
- Organizer
  the Asian Society for Pigment Cell Research and the Australasian Society for Dermatology Research conference 2013
- Place of Presentation
  シドニー（オーストラリア）
- Data Source
  KAKENHI-PROJECT-24791176

1. KUBO Akiharu (70335256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Suzuki Yusuke (80306696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 塩濱愛子 (40383731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 天谷雅行 (90212563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 宮井智浩 (30812549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Kawasaki Hiroshi 川崎 洋

KAWASAKI Hiroshi 川崎 洋

Research Projects

Research Products

Co-Researchers

Mechanistic investigation of atopic dermatitis associated with abnormality in endocrine and metabolism systems

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deep phenotype study for precision skin care in atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of the pathogenesis of atopic disease by using filaggrin deficient mice in dry environmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of tolerance in the airways by extracellular ATP

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of filaggrin-null mice in dry environment to understand the pathogenic mechanism of atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a New Model for Atopic Dermatitis Using Filaggrin Mutant MicePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Loss-of-function mutations within the filaggrin gene predispose to atopic dermatitis. 412011

Author(s)

Publisher

Data Source

[Journal Article] Multifaceted analysis of cross-tissue transcriptomes reveals phenotype-endotype associations in atopic dermatitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive Genomic Characterization of Staphylococcus aureus Isolated from Atopic Dermatitis Patients in Japan: Correlations with Disease Severity, Eruption Type, and Anatomical Site2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssinus extract.2010

Author(s)

Journal Title

Data Source

[Journal Article] SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing.

Author(s)

Journal Title

Data Source

[Presentation] アトピー性皮膚炎診療や発症予防への応用を目指した皮膚細菌叢解析2023

Author(s)

Organizer

Data Source

[Presentation] The thirteen bacterial species inversely correlated with disease activities of atopic dermatitis in human showed a biotherapeutic potential based on their suppressive effects in mice.2022

Author(s)

Organizer

Data Source

[Presentation] Microdissection-based spatial transcriptomics unraveled orchestrated epidermal-dermal interactions in atopic dermatitis2022

Author(s)

Organizer

Data Source

[Presentation] 皮膚細菌叢解析知見を臨床応用するためのDeep phenotype研究2022

Author(s)

Organizer

Data Source

[Presentation] Deep-phenotype study focusing on the diversity of skin characteristics in atopic dermatitis2022

Kawasaki Hiroshi 川崎洋

KAWASAKI Hiroshi 川崎洋