toyoshima masafumi 豊島将文

… Alternative Names

TOYOSHIMA Masafumi 豊島将文

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Researcher Number	70451581
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 日本医科大学, 医学部, 准教授 2016 – 2017: 東北大学, 大学病院, 講師 2015: 東北大学, 大学病院, 助教 2014: 東北大学, 大学院医学系研究科, 非常勤講師 2013 – 2014: 東北大学, 医学(系)研究科(研究院), 非常勤講師 … More 2013: 東北大学, 医学(系)研究科(研究院), 大学院非常勤講師 2012: 東北大学, 大学病院, 助教 2011: 東北大学, 医学(系)研究科(研究院), 助教 2008 – 2010: Tohoku University, 大学院・医学系研究科, 非常勤講師 2007: Tohoku University, 病院, 助教 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator Nucleic acid drug / siRNA / PAT-1 / 卵巣明細胞腺がん / c-MET / 阻害剤 / ｃ-MET / PAI-1 / 遺伝子解析 / 血栓症 … More / 卵巣明細胞腺癌 / in vivo imaging system / カゼインキナーゼ1 epsilon / 合成致死作用 / マウスモデル / アメリカ / 国際研究者交流 / CK-1e / FURIN / AuroraA / WEE1 / CK1e / 合成致死 / siRNAスクリーニング / 卵巣がん / c-Myc / マイクロアレイ / マイクロダイセクション / 遠隔転移 / 間葉上皮移行 / 上皮間葉移行 / 子宮癌肉腫 … More Except Principal Investigator 循環腫瘍DNA / 婦人科がん / digital PCR / Digital PCR / 循環腫瘍細胞 / 抗癌剤耐性 / エクソソーム / Liquid Biopsy / 卵胞液 / トランスフェリン / DNA損傷 / 卵管采 / p53変異 / 漿液性腺癌 / 卵巣がん / シスプラチン / 化学療法 / 薬剤耐性 / スクリーニング / 小胞体輸送 / ノックアウトマウス / ライソソーム / ユビキチン / マウス / 癌 / Hrs Less

Nucleic acid drug development targeting molecules identified as ovarian cancer therapeutic targets by high-throughput screeningPrincipal Investigator
- Principal Investigator
  
  豊島将文
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nippon Medical School
Integrated analysis of circulating tumor cells and DNA toward clinical application of liquid biopsy.
- Principal Investigator
  
  YAEGASHI Nobuo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Development of molecular targeted therapy by the inhibition of MET-PAI-1 pathway for the prevention of thrombosis in cancer patientsPrincipal Investigator
- Principal Investigator
  
  TOYOSHIMA Masafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Pathological examination of tubal fimbria and blood circulating DNA measurement toward the ultra-early detection of fallopian tubal cancer
- Principal Investigator
  
  YAEGASHI Nobuo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
The therapeutic strategy toward overcoming drug resistance of gynecologic cancers utilizing high throughput screening.
- Principal Investigator
  
  YAEGASHI Nobuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Identification of new molecular target for ovarian cancer via functional genomic analysisPrincipal Investigator
- Principal Investigator
  
  TOYOSHIMA Masafumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
A fundamental research for developing ubiquitin-targeted cancer therapies utilizing vesicular transport related molecules Hrs knocked-out mice.
- Principal Investigator
  
  YAEGASHI Nobuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
The search for EMT-related genes using clinical specimens of the uterine carcinosarcomaPrincipal Investigator
- Principal Investigator
  
  TOYOSHIMA Masafumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Other

[Book] 婦人科がん標準化学療法の実際子宮肉腫癌肉腫2008
- Author(s)
  豊島将文
- Total Pages
  188
- Publisher
  金原出版社
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] Ceramide nanoliposomes as a MLKL-1-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer2018
- Author(s)
  Xuewei Zhang, Kazuyuki Kitatani, Masafumi Toyoshima, Masumi Ishibashi, Toshinori Usui, Junko Minato, Mahy Egiz, Shogo Shigeta, Todd Fox, Tye Deering, Mark Kester, Nobuo Yaegashi
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17 Issue: 1 Pages: 50-59
- DOI
  10.1158/1535-7163.mct-17-0173
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11125, KAKENHI-PROJECT-16K15697
[Journal Article] Aggressive neuroendocrine tumor of the ovary with multiple metastases treated with everolimus: A case report2018
- Author(s)
  Kaiho-Sakuma Michiko、Toyoshima Masafumi、Watanabe Mika、Toki Asami、Kameda Satomi、Minato Takamichi、Niikura Hitoshi、Yaegashi Nobuo
- Journal Title
  
  Gynecologic Oncology Reports
  
  Volume: 23 Pages: 20-23
- DOI
  10.1016/j.gore.2018.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15697
[Journal Article] ASGO 4th International Workshop on Gynecologic Oncology2017
- Author(s)
  Shibuya Y, Toyoshima M* (*corresponding author), Yaegashi N
- Journal Title
  
  J Gynecol Onco
  
  Volume: 28（2） Issue: 1
- DOI
  10.3802/jgo.2017.28.e24
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-16K15697
[Journal Article] Leptomeningeal metastasis from gynecologic cancers diagnosed by brain MRI2017
- Author(s)
  Toyoshima M* (*corresponding author), Tsuji K, Shigeta S, Tokunaga H, Ito K, Watanabe Y, Yoshinaga K, Otsuki T, Niikura H, Yaegashi N
- Journal Title
  
  Clinical Imaging
  
  Volume: 41 Pages: 42-47
- DOI
  10.1016/j.clinimag.2016.09.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-16K15697
[Journal Article] Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers2017
- Author(s)
  Hasegawa-Minato Junko、Toyoshima Masafumi、Ishibashi Masumi、Zhang Xuewei、Shigeta Shogo、Grandori Carla、Kitatani Kazuyuki、Yaegashi Nobuo
- Journal Title
  
  Oncotarget
  
  Volume: 9（3） Issue: 3 Pages: 3483-3496
- DOI
  10.18632/oncotarget.23322
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15697
[Journal Article] Steroid Sulfatase Inhibitor Reduces Proliferation of Ishikawa Endometrial Cancer Cells in Co-Culture Systems2016
- Author(s)
  Nishimoto M, Toyoshima M* (*corresponding author), Shiga N, Utsunomiya H,Tsuji K, Suzuki F, Nagase S, Suzuki T, Sasano H, Ito K, Yaegashi N
- Journal Title
  
  OJEMD
  
  Volume: 6 Issue: 09 Pages: 193-204
- DOI
  10.4236/ojemd.2016.69025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462509
[Journal Article] Cytokeratin 7-positive/cytokeratin 20-negative cecal adenocarcinoma metastatic to the uterine cervix: a case report2016
- Author(s)
  Toyoshima M* (*corresponding author), Momono Y, Makino H, Kudo T, Oka N, Sakurada J, Suzuki H, Kodama H, Yoshinaga K
- Journal Title
  
  World Journal of Surgical Oncology
  
  Volume: - Issue: 1
- DOI
  10.1186/s12957-016-0774-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid2015
- Author(s)
  Kitatani K, Usui T, Sriraman S, Toyoshima M, Ishibashi M, Shigeta S, Nagase S, Sakamoto M, Hannun Y, Torchilin V, Okazaki T, Ogiso H, Yaegashi N
- Journal Title
  
  Oncogene
  
  Volume: - Issue: 21 Pages: 2801-2812
- DOI
  10.1038/onc.2015.330
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710, KAKENHI-PROJECT-26861304
[Journal Article] Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1:the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer.2015
- Author(s)
  Shigeta S, Toyoshima M* (*corresponding author), Ishibashi M, Usui T, Kitatani K*, Yaegashi N
- Journal Title
  
  Oncogene
  
  Volume: - Issue: 27 Pages: 3577-3586
- DOI
  10.1038/onc.2015.425
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Spontaneous retroperitoneal hemorrhage caused by rupture of an ovarian artery aneurysm: a case report and review of the literature.2015
- Author(s)
  Toyoshima M, Kudo T, Igeta S, Makino H, Momono Y, Shima T, Matsuura R, Ishigaki N, Akagi K,Takeyama Y, Iwahashi H, Rikimaru H, Sato A, Yoshinaga K
- Journal Title
  
  Journal of Medical Case Reports
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390375
[Journal Article] Spontaneous retroperitoneal hemorrhage caused by rupture of an ovarian artery aneurysm: a case report and review of the literature.2015
- Author(s)
  Toyoshima M, Kudo T, Igeta S, Makino H, Momono Y, Shima T, Matsuura R, Ishigaki N, Akagi K,Takeyama Y, Iwahashi H, Rikimaru H, Sato A, Yoshinaga K.
- Journal Title
  
  Journal of Medical Case Reports
  
  Volume: 9 Issue: 1 Pages: 84-84
- DOI
  10.1186/s13256-015-0553-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670710
[Journal Article] Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer.2015
- Author(s)
  Mashiko S, Kitatani K, Toyoshima M, Ichimura A, Dan T, Usui T, Ishibashi M, Shigeta S, Nagase S, Miyata T, Yaegashi N
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 16 Issue: 2 Pages: 253-260
- DOI
  10.1080/15384047.2014.1001271
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-24592498, KAKENHI-PROJECT-25860185, KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Solitary uterine metastasis of invasive lobular carcinoma after adjuvant endocrine therapy: a case report.2015
- Author(s)
  Toyoshima M, Iwahashi H, Shima T, Hayasaka A, Kudo T, Makino H, Igeta S, Matsuura R, Ishigaki N, Akagi K, Sakurada J, Suzuki H, Yoshinaga K
- Journal Title
  
  Journal of Medical Case Reports
  
  Volume: 9 Issue: 1 Pages: 47-47
- DOI
  10.1186/s13256-014-0511-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Paclitaxel-carboplatin for advanced or recurrent carcinosarcoma of the uterus: the Japan Uterine Sarcoma Group and Tohoku Gynecologic Cancer Unit Study2014
- Author(s)
  Tadao Takano,Takeo Otsuki,Hideki Tokunaga,Masafumi Toyoshima,Hiroki Utsunomiya,Satoru Nagase,Hitoshi Niikura,Kiyoshi Ito,Nobuo Yaegashi,Hidekazu Yamada,Toru Tase,Masahiro Kagabu,Tadahiro Shoji,Toru Sugiyama,Naoki Sato,Toshio Fujimoto,Yukihiro Terada, Junzo Kigawa,et al
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: accepted Issue: 6 Pages: 1052-1058
- DOI
  10.1007/s10147-013-0658-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Molecular Pathogenesis of Uterine Serous Carcinoma2014
- Author(s)
  Satoru Nagase, Fumihiko Suzuki, Hideki Tokunaga, Masafumi Toyoshima, Hiroki Utsunomiya, Hitoshi Niikura, Nobuo Yaegashi
- Journal Title
  
  Curr Obstet Gynecol Rep
  
  Volume: (3) Pages: 33-39
- Data Source
  KAKENHI-PROJECT-23791801
[Journal Article] Outcomes of Abdominal Radical Trachelectomy: Results of a Multicenter Prospective Cohort Study in a Tohoku Gynecologic Cancer Unit.2014
- Author(s)
  Tokunaga H, Watanabe Y, Niikura H, Nagase S, Toyoshima M, Shiro R, Yoshihito Yokoyama Y, Mizunuma H, Ohta T, Nishiyama H, Watanabe T, Sato N, Sugiyama T, Takano T, Takahashi F, Yaegashi N
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: in press Issue: 4 Pages: 776-780
- DOI
  10.1007/s10147-014-0763-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Molecular Pathogenesis of Uterine Serous Carcinoma2014
- Author(s)
  Satoru Nagase ・ Fumihiko Suzuki ・ Hideki Tokunaga ・Masafumi Toyoshima ・ Hiroki Utsunomiya ・Hitoshi Niikura ・ Nobuo Yaegashi
- Journal Title
  
  Curr Obstet Gynecol Rep
  
  Volume: 3 Issue: 1 Pages: 33-39
- DOI
  10.1007/s13669-013-0069-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-24592498
[Journal Article] Paclitaxel–carboplatin for advanced or recurrent carcinosarcoma of the uterus : the Japan Uterine Sarcoma Group and Tohoku Gynecologic Cancer Unit Study2014
- Author(s)
  Tadao Takano, Takeo Otsuki, Hideki Tokunaga, Masafumi Toyoshima, Hiroki Utsunomiya, Satoru Nagase, Hitoshi Niikura, Kiyoshi Ito, Nobuo Yaegashi, Hidekazu Yamada, Toru Tase, Masahiro Kagabu, Tadahiro Shoji, Toru Sugiyama, Naoki Sato, Toshio Fujimoto, Yukihiro Terada, Kenji Nakahara, Hirohisa Kurachi, Yoshihito Yokoyama, Hideki Mizunuma, Shu Soeda, Hiroshi Nishiyama, Takashi Matsumoto, Shinya Sato, Muneaki Shimada, Junzo Kigawa
- Journal Title
  
  Int J Clin Oncol
  
  Volume: (PMID : 24395448)
- Data Source
  KAKENHI-PROJECT-23791801
[Journal Article] Clinical outcome of pelvic exenteration in patients with advanced or recurrent uterine cervical cancer.2014
- Author(s)
  Tanaka S, Nagase S, Kaiho-Sakuma M, Nagai T, Kurosawa H, Toyoshima M, Tokunaga H, Otsuki T, Utsunomiya H, Takano T, Niikura H, Ito K, Yaegashi N.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 19 Issue: 1 Pages: 133-138
- DOI
  10.1007/s10147-013-0534-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591845, KAKENHI-PROJECT-23592431, KAKENHI-PROJECT-23592432, KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-23791805, KAKENHI-PROJECT-24390375
[Journal Article] Evaluation of Postoperative Chemotherapy in Patients with Uterine Carcinosarcoma: A Retrospective Survey of the Tohoku Gynecologic Cancer Unit.2014
- Author(s)
  Otsuki A, Otsuki T, Tokunaga H, Niikura H, Nagase S, Sugiyama T, Toyoshima M, Utsunomiya H, Yokoyama Y, Mizunuma H, Sato N, Terada Y, Shoji T, Sugiyama T, Nakahara K, Ohta T, Yamada H, Tase T, Nishiyama H, Fujimori K, Takano T, Takahashi F, Watanabe Y, Yaegashi N
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390375
[Journal Article] Feasibility study of gemcitabine plus docetaxel in advanced or recurrent uterine leiomyosarcoma and undifferentiated endometrial sarcoma in Japan2013
- Author(s)
  Takano T, Niikura H, Ito K, Nagase S, Utsunomiya H, Otsuki T, Toyoshima M, Tokunaga H, Kaiho-Sakuma M, Shiga N, Nagai T, Tanaka S, Otsuki A, Kurosawa H, Shigeta S, Yamaguchi T, Yaegashi N.
- Journal Title
  
  International Journal of Clinical Oncology.
  
  Volume: - Issue: 5 Pages: 897-905
- DOI
  10.1007/s10147-013-0627-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791802, KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
[Journal Article] Small Cell Carcinoma of the Uterine Cervix: Clinical Outcome of Concurrent Chemoradiotherapy with a Multidrug Regimen2013
- Author(s)
  Hideki Tokunaga, Satoru Nagase, Kosuke Yoshinaga, Sota Tanaka, Tomyuki Nagai, Hiroki Kurosawa, Michiko Kaiho-Sakuma, Masafumi Toyoshima, et al
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 229 Issue: 1 Pages: 75-81
- DOI
  10.1620/tjem.229.75
- NAID
  130004460037
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-24390375
[Journal Article] Small Cell Carcinoma of the Uteruine Cervix : Clinical Outcome of concurrent Chemoradiotherapy with a Multidrug Regimen2013
- Author(s)
  Hideki Tokunaga, Satoru Nagase, Kosuke Yoshinaga, Sota Tanaka, Tomyuki Nagai, Hiroki Kurosawa, Michiko Kaiho-Sakuma, Masafumi Toyoshima, Takeo Otsuki, Hiroki Utsunomiya, Tadao Takano, Hitoshi Niikura, Kiyoshi ito and Nobuo Yaegashi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 229(1) Pages: 75-81
- Data Source
  KAKENHI-PROJECT-23791801
[Journal Article] Tracer injection sites and combinations for sentinel lymph node detection in patients with endometrial cancer.2013
- Author(s)
  Niikura H, Kaiho-Sakuma M, Tokunaga H, Toyoshima M, Utsunomiya H, Nagase S, Takano T, Watanabe M, Ito K, Yaegashi N
- Journal Title
  
  Gynecol Oncol.
  
  Volume: 131 Issue: 2 Pages: 299-303
- DOI
  10.1016/j.ygyno.2013.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591845, KAKENHI-PROJECT-23592431, KAKENHI-PROJECT-23592432, KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-23791805
[Journal Article] Carcinosarcoma of the uterine cervix with a clear cell2013
- Author(s)
  Naomi Shiga, Masafumi Toyoshima, Jun-ichi Akahira, Satoru Nagase, Hitoshi Niikura, Nobuo Yaegashi
- Journal Title
  
  Int Canc Conf J
  
  Volume: 2(3) Issue: 3 Pages: 154-156
- DOI
  10.1007/s13691-012-0080-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-23791802
[Journal Article] Carcinosarcoma of the uterine cervix with a clear cell adenocarcinoma component2013
- Author(s)
  Naomi Shiga, Masafumi Toyoshima, Jun-ichi Akahira, Satoru Nagase, Hitoshi Niikura, Nobuo Yaegashi
- Journal Title
  
  Int Canc Conf J
  
  Volume: Volume 2(3) Pages: 154-156
- Data Source
  KAKENHI-PROJECT-23791801
[Journal Article] MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency2012
- Author(s)
  Russell Moser, Masafumi Toyoshima, Kristin Robinson, Kay E. Gurley, Heather L. Howie, Jerry Davison, Martin Morgan, Christpher J. Kemp and Carla Grandori
- Journal Title
  
  Mol. Cancer Research
  
  Volume: 10 Issue: 4 Pages: 535-545
- DOI
  10.1158/1541-7786.mcr-11-0508
- Data Source
  KAKENHI-PROJECT-23791801
[Journal Article] Hysterescopic inspection and total curettage are insufficient fordiscriminating endometrial cancer from atypical endometrial hyperplasia2012
- Author(s)
  Hiroki Kurosawa, Kiyoshi ito, Hitoshi Nikura, Tadao Takano, Satoru Nagase, Hiroki Ustunomiya, Takeo Otsuki, Masafumi Toyoshima, Tomoyuki Nagai, Souta Tanaka, Mika Watanabe and Nobuo Yaegashi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 228 Pages: 365-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390375
[Journal Article] Functional Genomics Identifies Therapeutic Targets for MYC-Driven Cancer2012
- Author(s)
  Masafumi Toyoshima , Heather L Howie , Maki Imakura , Ryan M Walsh , James E Annis , Aaron N. Chang ,et al
- Journal Title
  
  PNAS
  
  Volume: 109 Issue: 24 Pages: 9545-9550
- DOI
  10.1073/pnas.1121119109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791801, KAKENHI-PROJECT-24390375
[Journal Article] Hysterescopic inspection and total curettage are insufficient for discriminating endometrial cancer from atypical endometrial hyperplasia2012
- Author(s)
  Hiroki Kurosawa, Kiyoshi ito, Hitoshi Nikura, Tadao Takano, Satoru Nagase, Hiroki Ustunomiya, Takeo Otsuki, Masafumi Toyoshima, Tomoyuki Nagai, Souta Tanaka, Mika Watanabe and Nobuo Yaegashi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 228(4) Pages: 365-370
- Data Source
  KAKENHI-PROJECT-23791801
[Journal Article] Generation of a syngeneic mouse model to study the intraperitoneal dissemination of ovarian cancer with in vivo luciferase imaging.2009
- Author(s)
  Toyoshima M, Tanaka Y, Matumoto M, Yamazaki M, Nagase S, Sugamura K and Yaegashi N.
- Journal Title
  
  Luminescence (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] Generation of a syngeneic mouse model to study the intraperitoneal metastasis of ovarian cancer with in vivo luciferase imaging.2009
- Author(s)
  Toyoshima M, Tanaka Y, Matumoto M, Yamazaki M, Nagase S, Sugamura K, Yaegashi N.
- Journal Title
  
  Luminescence. 24
  
  Pages: 324-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390428
[Journal Article] Generation of a syngeneic mouse model to study the intraperitoneal metastasis of ovarian cancer with in vivo luciferase imaging.2009
- Author(s)
  Toyoshima M, Tanaka Y, Matumoto M, Yamazaki M, Nagase S, Sugamura K, Yaegashi N
- Journal Title
  
  Luminescence 24
  
  Pages: 324-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390428
[Journal Article] 子宮体がんに対する治療戦略2008
- Author(s)
  八重樫伸生、新倉仁、豊島将文
- Journal Title
  
  Focus in oncology 8
  
  Pages: 8-10
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] Loss of hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration.2008
- Author(s)
  Tamai K, Toyoshima M, Tanaka N, Yamamoto N, Owada Y, Kiyonari H, Murata K, Ueno Y, Ono M, Shimosegawa T, Yaegashi N, Watanabe M, Sugamura K.
- Journal Title
  
  Am J Pathol. 173
  
  Pages: 1806-1817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390428
[Journal Article] 子宮体癌の診断と治療2008
- Author(s)
  豊島将文、八重樫伸生
- Journal Title
  
  病理と臨床 26(4)
  
  Pages: 335-339
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] A diagnosis and treatment of the uterine body carcinoma.(in Japanese)2008
- Author(s)
  Masafumi Toyoshima and Nobuo Yaegashi
- Journal Title
  
  Byori To Rinsho 26
  
  Pages: 335-339
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] Loss of Hrs in the Central Nervous System Causes Accumulation of Ubiquitinated Proteins and Neurodegeneration2008
- Author(s)
  Tamai K, Toyoshima M, Tanaka N, Yamamoto N, Owada Y, Kiyonari H, Murata K, Ueno Y, Ono M, Shimosegawa T, Yaegashi N, Watanabe M, Sugamura K
- Journal Title
  
  Am J Pathol. 173(6)
  
  Pages: 1806-1817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] The therapeutic strategy for the uterine body cancer(in Japanese)2008
- Author(s)
  Nobuo Yaegashi, Hitoshi Niikura, Masafumi Toyoshima
- Journal Title
  
  Focus on Oncology 8
  
  Pages: 8-10
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] Loss of Hrs in the Central Nervous System Causes Accumulation of Ubiquitinated Proteins and Neurodegeneration2008
- Author(s)
  Tamai K, Toyoshima M, Tanaka N, Yamamoto N, Owada Y, Kiyonari H, Murata K, Ueno Y, Ono M, Shimosegawa T, Yaegashi N, Watanabe M, Sugamura K
- Journal Title
  
  Am J Pathol 173(6)
  
  Pages: 1806-1817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890022
[Journal Article] Inhibition of Tumor Growth and Metastasis by Depletion of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hrs), a Key Regulator of Monoubiquitinated Protein Sorting: Hrs-Mediated Regulation of E-Cadherin and B-Catenin2007
- Author(s)
  Masafumi Toyoshima, Nobuyuki Tanaka, Jun Aoki, Yoshinori Tanaka, Kazuko Murata, Masanao Kyuuma, Hideyuki Kobayashi, Naoto Ishii, Nobuo Yaegashi, Kazuo Sugamura
- Journal Title
  
  Cancer Research 67
  
  Pages: 5162-5171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890022
[Presentation] Novel implications of La-Related Protein 4, an RNA chaperon, in ovarian cancer metastasis suppression2017
- Author(s)
  Egiz M, Kitatani K, Toyoshima M, Ishibashi M, Shigeta S, Minato J, Yaegashi N
- Organizer
  第69回日本産科婦人科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] Ceramide synthase 2-ceramide synthesis pathway modulates the metastatic potential of ovarian cancer2017
- Author(s)
  Kitatani K, Zhang X, Toyoshima M, Egiz M, Minato J, Ishibashi M, Shigeta S, Yaegashi N
- Organizer
  第69回日本産科婦人科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] 卵巣癌における c-Mycと合成致死作用を持つ治療標的分子の探索2017
- Author(s)
  湊純子、豊島将文、北谷和之、重田昌吾、石橋ますみ、八重樫伸生
- Organizer
  第5回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  大阪医科大学　本部北キャンパス（大阪府高槻市）
- Year and Date
  2017-02-25
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] 卵巣がんに対するセラミドナノリポソーム製剤の抗腫瘍作用2017
- Author(s)
  張　雪薇、北谷和之、豊島将文、石橋ますみ、臼井利典、湊　純子、重田昌吾、Mark Kester、八重樫伸生
- Organizer
  第5回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  大阪医科大学　本部北キャンパス（大阪府高槻市）
- Year and Date
  2017-02-25
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] 卵巣がんに対するセラミドナノリポソーム製剤の抗腫瘍作用2017
- Author(s)
  張　雪薇、北谷和之、豊島将文、石橋ますみ、臼井利典、湊　純子、重田昌吾、Mark Kester、八重樫伸生
- Organizer
  第5回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  大阪医科大学　本部北キャンパス（大阪府高槻市）
- Year and Date
  2017-02-25
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 卵巣癌における c-Mycと合成致死作用を持つ治療標的分子の探索2017
- Author(s)
  湊純子、豊島将文、北谷和之、重田昌吾、石橋ますみ、八重樫伸生
- Organizer
  第5回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  大阪医科大学　本部北キャンパス（大阪府高槻市）
- Year and Date
  2017-02-25
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer2017
- Author(s)
  Ishibashi M, Toyoshima M, Zhang X, Minato J, Shigeta S, Kitatani K, Yaegashi N
- Organizer
  第69回日本産科婦人科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] 卵巣がん転移制御へのセラミド合成酵素 2 の関与2017
- Author(s)
  北谷和之、張雪薇、臼井利典、豊島将文、重田昌吾、石橋ますみ、湊純子、小木曽英夫、岡崎俊朗、八重樫伸生
- Organizer
  第5回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  大阪医科大学　本部北キャンパス（大阪府高槻市）
- Year and Date
  2017-02-25
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 卵巣がん転移制御へのセラミド合成酵素 2 の関与2017
- Author(s)
  北谷和之、張雪薇、臼井利典、豊島将文、重田昌吾、石橋ますみ、湊純子、小木曽英夫、岡崎俊朗、八重樫伸生
- Organizer
  第5回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  大阪医科大学　本部北キャンパス（大阪府高槻市）
- Year and Date
  2017-02-25
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] Anti-tumor activities of ceramide nanoliposomes in ovarian cancer2017
- Author(s)
  Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Shigeta S, Minato J, Yaegashi N
- Organizer
  第69回日本産科婦人科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] セラミドナノリポソームはネクロプトーシスを誘導する薬剤である2016
- Author(s)
  張雪薇、豊島将文、石橋ますみ、臼井利典、湊純子、重田昌吾、Ｍａｒｋ　Ｋｅｓｔｅｒ，北谷和之、八重樫伸生
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 子宮体癌のセンチネルリンパ節生検における捺印細胞診の診断精度についての検討2016
- Author(s)
  佐藤いずみ、岡本聡、新倉仁、重田昌吾、橋本千明、辻圭太、徳永英樹、豊島将文、三浦弘守、渡部みか、八重樫伸生
- Organizer
  第55回日本臨床細胞学会秋期大会
- Place of Presentation
  別府国際コンベンションセンターＢ-Ｃon Ｐlaza（大分県別府市）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] セラミドナノリポソーム製剤によるネクロプト―シスの誘導2016
- Author(s)
  張　雪薇、北谷　和之、豊島　将文、石橋　ますみ、臼井　利典、湊　純子、重田　昌吾、Mark Kester、八重樫　伸生
- Organizer
  第9回セラミド研究会　学術集会
- Place of Presentation
  東京ユビキタス協創広場CANVAS（東京都中央区）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Involvement of the receptor tyrosine kinase TIE-1 in the platinum-resistance of ovarian cancer cells2016
- Author(s)
  Ishibashi M, Toyoshima M, Zhang X, Minato J, Shigeta S, Kitatani K, Yaegashi N
- Organizer
  Marsha Rikin the 11th Ovarian Cancer Research Symposium
- Place of Presentation
  ワシントン大学（Seattle, USA）
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] セラミド合成酵素による癌転移制御2016
- Author(s)
  北谷和之，張雪薇，臼井利典，豊島将文，重田昌吾，Mahy Egiz，湊　純子，石橋ますみ，小木曽英夫，岡崎俊朗，八重樫伸生
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  秋田キャッスルホテル（秋田市）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 子宮体癌のセンチネルリンパ節生検における捺印細胞診の診断精度についての検討2016
- Author(s)
  佐藤いずみ、岡本聡、新倉仁、重田昌吾、橋本千明、辻圭太、徳永英樹、豊島将文、三浦弘守、渡部みか、八重樫伸生
- Organizer
  第55回日本臨床細胞学会秋期大会
- Place of Presentation
  別府国際コンベンションセンターＢ-Ｃon Ｐlaza（大分県別府市）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Furin, a pro-protein convertase, is a novel molecular target for c-Myc-driven ovarian cancers2016
- Author(s)
  Minato J, Toyoshima M, Kitatani K, Shigeta S, Ishibashi M, Yaegashi N
- Organizer
  The 13th International Congress of Human Genetics
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2016-04-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Transferrin in follicular fluid can facilitate DNA double-strand breaks to fallopian tube epithelium: possible involvement of transferrin in the carcinogenesis of high-grade serous ovarian cancer.2016
- Author(s)
  Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Masumi Ishibashi, Toshinori Usui, Junko Minato, Nobuo Yaegashi
- Organizer
  Society for Reproductive Investigation 63th scientific annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 卵巣がん転移に関わるセラミド生成代謝酵素2016
- Author(s)
  北谷和之，張雪薇，臼井利典，豊島将文，重田昌吾，石橋ますみ，湊純子，小木曽英夫，岡崎俊朗，八重樫伸生
- Organizer
  第4回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  岐阜大学サテライトキャンパス（岐阜市）
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] Transferrin in follicular fluid can facilitate DNA double-strand breaks to fallopian tube epithelium: possible involvement of transferrin in the carcinogenesis of high-grade serous ovarian cancer.2016
- Author(s)
  Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Masumi Ishibashi, Toshinori Usui, Junko Minato, Nobuo Yaegashi
- Organizer
  Society for Reproductive Investigation 63th scientific annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] 卵巣がん細胞に対するセラミド卵巣がん細胞に対するセラミドナノリポソームの抗腫瘍効果-ネクロプト－シスの誘導-2016
- Author(s)
  張雪薇, 豊島将文, 石橋ますみ, 臼井利典, 湊純子, 重田昌吾, Mark Kester, 北谷和之, 八重樫伸生
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  秋田キャッスルホテル（秋田市）
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Casein kinase I epsilon is a novel molecular target for c-Myc driven ovarian cancers2016
- Author(s)
  Toyoshima M, Kitatani K, Shigeta S, Ishibashi M, Hasegawa-Minato J, Yaegashi N
- Organizer
  第68回日本産科婦人科学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 卵巣がん転移に関わるセラミド生成代謝酵素2016
- Author(s)
  北谷和之，張雪薇，臼井利典，豊島将文，重田昌吾，石橋ますみ，湊純子，小木曽英夫，岡崎俊朗，八重樫伸生
- Organizer
  第4回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  岐阜大学サテライトキャンパス（岐阜市）
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] フローサイトメトリーを利用した腹水細胞診断法のパイロットスタディ2016
- Author(s)
  徳永英樹、岡本聡、渡部洋、重田昌吾、辻圭太、海法道子、豊島将文、新倉仁、八重樫伸生
- Organizer
  第55回日本臨床細胞学会秋期大会
- Place of Presentation
  別府国際コンベンションセンターＢ-Ｃon Ｐlaza（大分県別府市）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 大規模 siRNA スクリーニングを用いた卵巣がんのシスプラチン抵抗性を克服する分子標的の検討2016
- Author(s)
  石橋ますみ、豊島将文、Mahy Egiz、張雪薇、湊純子、重田昌吾、北谷和之、八重樫伸生
- Organizer
  第4回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  岐阜大学サテライトキャンパス（岐阜市）
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] セラミドナノリポソームによる新しい細胞死ネクロプトーシス2016
- Author(s)
  張雪薇、北谷和之、石橋ますみ、湊純子、豊島将文、八重樫伸生
- Organizer
  第15回日本婦人がん分子標的研究会
- Place of Presentation
  ホテルニューオータニ札幌（北海道札幌市）
- Year and Date
  2016-08-20
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 大規模 siRNA スクリーニングを用いた卵巣がんのシスプラチン抵抗性を克服する分子標的の検討2016
- Author(s)
  石橋ますみ、豊島将文、Mahy Egiz、張雪薇、湊純子、重田昌吾、北谷和之、八重樫伸生
- Organizer
  第4回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  岐阜大学サテライトキャンパス（岐阜市）
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] セラミドナノリポソーム製剤によるネクロプト―シスの誘導2016
- Author(s)
  張　雪薇、北谷　和之、豊島　将文、石橋　ますみ、臼井　利典、湊　純子、重田　昌吾、Mark Kester、八重樫　伸生
- Organizer
  第9回セラミド研究会　学術集会
- Place of Presentation
  東京ユビキタス協創広場CANVAS（東京都中央区）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] 子宮頸癌のセンチネルリンパ節生検における捺印細胞診の診断精度についての検討2016
- Author(s)
  佐藤いずみ、岡本聡、新倉仁、橋本千明、徳永英樹、豊島将文、三浦弘守、渡部みか、渡部洋、八重樫伸生
- Organizer
  第57回日本臨床細胞学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-05-29
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] フローサイトメトリーを利用した腹水細胞診断法のパイロットスタディ2016
- Author(s)
  徳永英樹、岡本聡、渡部洋、重田昌吾、辻圭太、海法道子、豊島将文、新倉仁、八重樫伸生
- Organizer
  第55回日本臨床細胞学会秋期大会
- Place of Presentation
  別府国際コンベンションセンターＢ-Ｃon Ｐlaza（大分県別府市）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-16K15697
[Presentation] Transferrin is involved in the carcinogenesis of high-grade serous ovarian cancer by facilitating the DNA double-strand breaks via transferrin receptor 1 in fallopian tube.2016
- Author(s)
  Shigeta Ｓ, Toyoshima M, Kitatani K, Ishibashi M, Minato J, Yaegashi N
- Organizer
  第68回日本産科婦人科学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Transferrin facilitates DNA-double strand breaks via transferrin receptor 1 in human fallopian tube epithelial cells: possible involvement of transferrin in carcinogenesis.2015
- Author(s)
  Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Usui T, Yaegashi N
- Organizer
  Society for Reproductive Investigation 62th scientific annual meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] Transferrin facilitates the formation of DNA-double strand breaks via Transferrin receptor 1 in fallopian tube epithelial cells.2015
- Author(s)
  Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Junko Minato, Masumi Ishibashi, Toshinori Usui, Nobuo Yaegashi
- Organizer
  AACR special conference　Advance in Ovarian Cancer Research
- Place of Presentation
  Orland, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 月経血や卵胞液に含まれるトランスフェリンはⅠ型トランスフェリン受容体を介して卵管上皮細胞におけるDNA二重鎖切断を誘導・増幅する2015
- Author(s)
  重田昌吾・豊島将文・北谷和之・石橋ますみ・八重樫伸生
- Organizer
  第67回日本産科婦人科学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] 月経血や卵胞液に含まれるトランスフェリンはⅠ型トランスフェリン受容体を介して卵管上皮細胞におけるDNA二重鎖切断を誘導・増幅する2015
- Author(s)
  重田昌吾・豊島将文・北谷和之・石橋ますみ・八重樫伸生
- Organizer
  第67回日本産科婦人科学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] 卵巣癌におけるc-mycと合成致死作用を持つ治療標的分子の探索2015
- Author(s)
  湊純子、豊島将文、北谷和之、重田昌吾、石橋ますみ、臼井利典、八重樫伸生
- Organizer
  第14回日本婦人科がん分子標的研究会
- Place of Presentation
  美ヶ原温泉ホテル翔峰（長野県松本市）
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] セラミドによる卵巣がん播種転移制御2015
- Author(s)
  北谷和之、豊島将文、臼井利典、重田昌吾、石橋ますみ、永瀬智、八重樫伸生
- Organizer
  第3回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  九州大学医学部百年講堂（福岡市）
- Year and Date
  2015-02-21
- Invited
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] セラミドによる卵巣がん播種転移制御2015
- Author(s)
  北谷和之、豊島将文、臼井利典、重田昌吾、石橋ますみ、永瀬智、八重樫伸生
- Organizer
  第3回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  九州大学医学部百年講堂（福岡市）
- Year and Date
  2015-02-21
- Invited
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] セラミドによる卵巣がん播種転移制御2015
- Author(s)
  北谷和之、豊島将文、臼井利典、重田昌吾、石橋ますみ、永瀬智、八重樫伸生
- Organizer
  第3回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  九州大学医学部百年講堂（福岡市）
- Year and Date
  2015-02-21
- Invited
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Transferrin facilitates the formation of DNA-double strand breaks via Transferrin receptor 1 in fallopian tube epithelial cells.2015
- Author(s)
  Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Junko Minato, Masumi Ishibashi, Toshinori Usui, Nobuo Yaegashi
- Organizer
  AACR special conference　Advance in Ovarian Cancer Research
- Place of Presentation
  Orland, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] 卵巣癌におけるc-mycと合成致死作用を持つ治療標的分子の探索2015
- Author(s)
  湊純子、豊島将文、北谷和之、重田昌吾、石橋ますみ、臼井利典、八重樫伸生
- Organizer
  第14回日本婦人科がん分子標的研究会
- Place of Presentation
  美ヶ原温泉ホテル翔峰（長野県松本市）
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Transferrin facilitates DNA-double strand breaks via transferrin receptor 1 in human fallopian tube epithelial cells: possible involvement of transferrin in carcinogenesis.2015
- Author(s)
  Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Usui T, Yaegashi N
- Organizer
  Society for Reproductive Investigation　62th scientific annual meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26462509
[Presentation] Transferrin facilitates DNA-double strand breaks via transferrin receptor 1 in human fallopian tube epithelial cells: possible involvement of transferrin in carcinogenesis.2015
- Author(s)
  Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Usui T, Yaegashi N.
- Organizer
  Society for Reproductive Investigation 62th scientific annual meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26670710
[Presentation] スフィンゴ脂質セラミドを利用した卵巣がん播種転移薬の可能性2014
- Author(s)
  北谷和之、豊島将文、臼井利典、重田昌吾、石橋ますみ、永瀬智、八重樫伸生
- Organizer
  第2回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京慈恵会医科大学（東京都港区）
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 大規模 siRNA スクリーニングを用いた卵巣がんのシスプラチン抵抗性を克服する分子標的の検討2014
- Author(s)
  石橋ますみ、豊島将文、北谷和之、増子さつき、重田昌吾、八重樫伸生
- Organizer
  第66回日本産科婦人科学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-18
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] セラミドによる細胞運動性の調節：セラミドリポソームの抗卵巣がん播種転移薬としての可能性2014
- Author(s)
  北谷和之，豊島将文，増子さつき，重田昌吾，石橋ますみ，永瀬智，八重樫伸生
- Organizer
  第66回日本産科婦人科学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-18
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] Investigation of PAI-1 as a new therapeutic target for ovarian cancer.2014
- Author(s)
  Satsuki Mashiko, Masafumi Toyoshima, Kazuyuki Kitatani , Shogo Shigeta , Masumi Ishibashi , Nobuo Yaegashi
- Organizer
  第66回日本産科婦人科学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-19
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 卵管上皮内腺癌におけるDNA二本鎖切断とp53発現の免疫組織学的検討2013
- Author(s)
  重田昌吾, 豊島将文, 増子さつき, 北谷和之, 八重樫伸生
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌(ポスター)
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 大規模siRNAスクリーニングを用いた卵巣がんのシスプラチン抵抗性を克服する分子標的の検討2013
- Author(s)
  石橋ますみ・豊島将文・北谷和之・増子さつき・重田昌吾・八重樫伸生
- Organizer
  第1回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京大学　伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] c-Myc高発現をバイオマーカーとした卵巣がんにおける治療標的分子の同定2013
- Author(s)
  豊島将文、北谷和之、増子さつき、重出昌吾、石橋ますみ、八重樫伸生
- Organizer
  第1回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 大規模siRNAスクリーニングを通じた、卵巣がんに対する新規治療標的分子の同定2013
- Author(s)
  豊島将文
- Organizer
  勝山館TYCOONS Seminar 2013
- Place of Presentation
  仙台
- Year and Date
  2013-08-03
- Invited
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] c-Myc高発現をバイオマーカーとした卵巣がんにおける治療標的分子の同定2013
- Author(s)
  豊島将文・北谷和之・増子さつき・重田昌吾・石橋ますみ・八重樫伸生
- Organizer
  第1回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京大学　伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 大規模siRNAスクリーニングを用いた卵巣がんのシスプラチン抵抗性を克服する分子標的の検討2013
- Author(s)
  石橋ますみ、豊島将文、北谷和之、増子さつき、重田昌吾、八重樫伸生
- Organizer
  第1回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 卵巣がん転移を標的にした創薬 : スフィンゴ脂質の利用2013
- Author(s)
  北谷和之, 豊島将文, 増子さつき, 重田昌吾, 石橋ますみ, 八重樫伸生
- Organizer
  第12回日本婦人科がん分子標的研究会講演
- Place of Presentation
  東大寺総合文化センター、奈良
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] c-Myc高発現をバイオマーカーとした卵巣がんにおける治療標的分子の同定2013
- Author(s)
  豊島将文, 北谷和之, 増子さつき, 重田昌吾, 石橋ますみ, 八重樫伸生
- Organizer
  第1回婦人科がんバイオマーカー研究会学術集会講演
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 卵巣明細胞腺癌におけるPAI-1の発現と血栓症発症の関連についての検討2013
- Author(s)
  増子さつき, 豊島将文, 北谷和之, 重田昌吾, 八重樫伸生
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌(ポスター)
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 大規模siRNAスクリーニングを用いた卵巣がんのシスプラチン抵抗性を克服する分子標的の検討2013
- Author(s)
  石橋ますみ, 豊島将文, 北谷和之, 増子さつき, 重田昌吾, 八重樫伸生
- Organizer
  第1回婦人科がんバイオマーカー研究会学術集会講演
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Epidemiology of the cervical cancer, and the Present State of Screening/Vaccination in Japan2013
- Author(s)
  Masafumi Toyoshima
- Organizer
  Phnom Penh Hotel 12th SCGO annual meeting Invited Phnom Penh, Cambodia
- Place of Presentation
  Phnom Penh, Cambodia
- Year and Date
  2013-08-09
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] I dentification of Targeted Therapies for Ovarian Cancers by Functional Genomics2013
- Author(s)
  Masafumi Toyoshima, Kazuyuki Kitatani, Satsuki Mashiko, Shogo Shigeta and Nobuo Yaegashi
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌(ポスター)
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted therapies for Ovarian Cancer by Functional Genomics2012
- Author(s)
  Masafumi Toyoshima
- Organizer
  Marsha Rikin the 9th Ovarian Cancer Research Symposium
- Place of Presentation
  Seattle, USA(招待講演)
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] Identification of Targeted therapies for Ovarian Cancer by Functional Genomics2012
- Author(s)
  Masafumi Toyoshima
- Organizer
  Marsha Rikin the 9th Ovarian Cancer Research Symposium
- Place of Presentation
  Seattle, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted therapies for Ovarian Cancer by Functional Genomics2012
- Author(s)
  Masafumi Toyoshima
- Organizer
  9th Ovarian Cancer Research Symposium
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Therapeutic targets for MYC-driven cancer2011
- Author(s)
  Masafumi Toyoshima
- Organizer
  Moscone Center West AACR-NCI-EORTC International Conference, Molecular Targets and Cancer Therapeutics
- Place of Presentation
  San Francisco, USA(ポスター)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted Therapies for c-Myc overexpressed Ovarian Cancers by Functional Genomics2011
- Author(s)
  豊島　将文
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 機能的ゲノミクスによる、卵巣がんにおけるc-Myc過剰発現と合成致死作用を持つ分子標的の探索2011
- Author(s)
  豊島将文
- Organizer
  第2回講習会講演
- Place of Presentation
  東北大学薬学部化合物ライブラリー、仙台
- Year and Date
  2011-12-20
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 機能的ゲノミクスによる、卵巣がんにおけるc-Myc過剰発現と合成致死作用を持つ分子標的の探索2011
- Author(s)
  豊島　将文
- Organizer
  化合物ライブラリー第2回講習会
- Place of Presentation
  東北大学薬学部
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 卵巣がんにおける新しい治療標的探索ツールとしての大規模siRNAスクリーニング、およびG2/Mチェックポイント関連分子の同定2011
- Author(s)
  豊島　将文
- Organizer
  第63回日本産科婦人科学会学術総会
- Place of Presentation
  リーガロイヤルホテル（大阪）
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] casein kinase 1 epsilonはc-Myc過剰発現をバイオマーカーとした、卵巣がんの新規治療標的である2011
- Author(s)
  豊島　将文
- Organizer
  第50回日本婦人科腫瘍学会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted Therapies for c-Myc overexpressed Ovarian Cancers by Functional Genomics2011
- Author(s)
  Masafumi Toyoshima
- Organizer
  第70回日本癌学会講演
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Therapeutic targets for MYC-driven cancer2011
- Author(s)
  Masafumi Toyoshima, Heather L. Howie, Carla Grandori
- Organizer
  AACR-NCI-EORTC International Conference, Molecular Targets and Cancer Therapeutics(招待講演)
- Place of Presentation
  Moscone Center West (SanFranscisco, USA)
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted Therapies for MYC-amplified Ovarian Cancers by Functional Genomics2010
- Author(s)
  豊島将文
- Organizer
  第69回日本癌学会臓器別シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390428
[Presentation] Identification of Targeted Therapies for MYC-amplified Ovarian Cancers by Functional Genomics2010
- Author(s)
  豊島将文
- Organizer
  第69回日本癌学会臓器別シンポジウム(招待講演)
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390428
[Presentation] 子宮癌肉腫の病態とそれを踏まえた治療戦略2008
- Author(s)
  豊島将文
- Organizer
  日本婦人科腫瘍学会シンポジウム
- Place of Presentation
  名古屋市
- Year and Date
  2008-07-17
- Data Source
  KAKENHI-PROJECT-19890022
[Presentation] 子宮癌肉腫の病態とそれを踏まえた治療戦略2008
- Author(s)
  豊島将文
- Organizer
  第44回日本婦人科腫瘍学会シンポジウム
- Place of Presentation
  名古屋市
- Year and Date
  2008-07-17
- Data Source
  KAKENHI-PROJECT-19890022
[Presentation] 卵巣明細胞腺癌におけるPAI-1の発現と血栓症発症の関連についての検討
- Author(s)
  増子さつき・豊島将文・北谷和之・重田昌吾・八重樫伸生
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Epidemiology of the cervical cancer, and the Present State of Screening/Vaccination in Japan
- Author(s)
  Masafumi Toyoshima
- Organizer
  12th SCGO annual meeting
- Place of Presentation
  Phnom Penh, Cambodia
- Invited
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted Therapies for Ovarian Cancers by Functional Genomics
- Author(s)
  Masafumi　Toyoshima, Kazuyuki Kitatani, Satsuki Mashiko, Shogo Shigeta and Nobuo Yaegashi
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 卵巣がん転移を標的にした創薬:スフィンゴ脂質の利用
- Author(s)
  北谷和之・豊島将文・増子さつき・重田昌吾・石橋ますみ・八重樫伸生
- Organizer
  第12回日本婦人科がん分子標的研究会
- Place of Presentation
  東大寺総合文化センター、奈良市
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] Identification of Targeted Therapies for Ovarian Cancers by Functional Genomics
- Author(s)
  Masafumi　Toyoshima, Kazuyuki Kitatani, Satsuki Mashiko, Shogo Shigeta and Nobuo Yaegashi
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 大規模siRNAスクリーニングを通じた、卵巣がんに対する新規治療標的分子の同定
- Author(s)
  豊島将文
- Organizer
  TYCOONS Seminar 2013
- Place of Presentation
  勝山館、仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 卵巣がん転移を標的にした創薬:スフィンゴ脂質の利用
- Author(s)
  北谷和之・豊島将文・増子さつき・重田昌吾・石橋ますみ・八重樫伸生
- Organizer
  第12回日本婦人科がん分子標的研究会
- Place of Presentation
  東大寺総合文化センター、奈良市
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 卵管上皮内腺癌におけるDNA二本鎖切断とp53発現の免疫組織学的検討
- Author(s)
  重田昌吾・豊島将文・増子さつき・北谷和之・八重樫伸生
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23791801
[Presentation] 卵巣明細胞腺癌におけるPAI-1の発現と血栓症発症の関連についての検討
- Author(s)
  増子さつき・豊島将文・北谷和之・重田昌吾・八重樫伸生
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390375
[Presentation] 卵管上皮内腺癌におけるDNA二本鎖切断とp53発現の免疫組織学的検討
- Author(s)
  重田昌吾・豊島将文・増子さつき・北谷和之・八重樫伸生
- Organizer
  第65回日本産科婦人科学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390375
[]

1. YAEGASHI Nobuo (00241597)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
2. KITATANI Kazuyuki (40539235)

# of Collaborated Projects: 3 results

# of Collaborated Products: 40 results
3. SUGAMURA Kazuo (20117360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. NAGASE Satoru (00292326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. SUZUKI Fumihiko (20400343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. TAKAO Masashi (70216612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ISHIBASHI Masumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. MINATO Junko

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. ITO Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. UTSUNOMIYA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. KAIHO Michiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 志賀尚美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

toyoshima masafumi 豊島 将文

TOYOSHIMA Masafumi 豊島 将文

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Nucleic acid drug development targeting molecules identified as ovarian cancer therapeutic targets by high-throughput screeningPrincipal Investigator

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Integrated analysis of circulating tumor cells and DNA toward clinical application of liquid biopsy.

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Development of molecular targeted therapy by the inhibition of MET-PAI-1 pathway for the prevention of thrombosis in cancer patientsPrincipal Investigator

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Pathological examination of tubal fimbria and blood circulating DNA measurement toward the ultra-early detection of fallopian tubal cancer

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The therapeutic strategy toward overcoming drug resistance of gynecologic cancers utilizing high throughput screening.

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Identification of new molecular target for ovarian cancer via functional genomic analysisPrincipal Investigator

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A fundamental research for developing ubiquitin-targeted cancer therapies utilizing vesicular transport related molecules Hrs knocked-out mice.

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The search for EMT-related genes using clinical specimens of the uterine carcinosarcomaPrincipal Investigator

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[Book] 婦人科がん標準化学療法の実際子宮肉腫癌肉腫2008

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[Journal Article] Ceramide nanoliposomes as a MLKL-1-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer2018

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[Journal Article] Aggressive neuroendocrine tumor of the ovary with multiple metastases treated with everolimus: A case report2018

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[Journal Article] ASGO 4th International Workshop on Gynecologic Oncology2017

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[Journal Article] Leptomeningeal metastasis from gynecologic cancers diagnosed by brain MRI2017

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[Journal Article] Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers2017

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toyoshima masafumi 豊島将文

TOYOSHIMA Masafumi 豊島将文