Suzuki Masanobu 鈴木正宣

Researcher Number	70455658
Other IDs
Affiliation (Current)	2025: 北海道大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 北海道大学, 医学研究院, 助教 2018: 北海道大学, 大学病院, 助教 2017: 北海道大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator 好酸球性副鼻腔炎 / 慢性副鼻腔炎 / サイトカイン / 鼻ポリープ / アレルギー学 / 耳鼻咽喉科学 / コラーゲン / 鼻粘膜上皮細胞 / SIRT1 / HDAC … More / エピジェネティック / MMP9 / リモデリング / 自然免疫シグナル / TLR3 / PolyIC / TLR / TGF-β / メタロサイオニン / 亜鉛 / レスベラトロール / サイトカイン産生 Less

Type2炎症による鼻粘膜支持組織への影響Principal Investigator
- Principal Investigator
  
  鈴木正宣
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Hokkaido University
細胞内亜鉛とTGF-βシグナル制御による好酸球性副鼻腔炎の新規治療法の開発Principal Investigator
- Principal Investigator
  
  鈴木正宣
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Hokkaido University
Regulatory mechanisms of cytokines in ECRSPrincipal Investigator
- Principal Investigator
  
  Suzuki Masanobu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Hokkaido University
好酸球性副鼻腔炎の根治を施行したSIRT-1活性化剤の基礎的研究Principal Investigator
- Principal Investigator
  
  鈴木正宣
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation Book

[Book] Antibiofilm Strategies2022
- Author(s)
  Katharina Richter, Kasper Norskov Kragh, Masanobu Suzuki et al.
- Total Pages
  588
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18K16871
[Journal Article] Targeted next-generation sequencing of Japanese patients with sinonasal mucosal melanomas identifies frequent NRAS and CTNNB1 mutations2024
- Author(s)
  Tsushima Nayuta、Kano Satoshi、Hatanaka Kanako C.、Suzuki Takayoshi、Hamada Seijiro、Idogawa Hiroshi、Nakamaru Yuji、Suzuki Masanobu、Hatanaka Yutaka、Homma Akihiro
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 51 Issue: 2 Pages: 313-319
- DOI
  10.1016/j.anl.2023.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-19K18754
[Journal Article] Treatment outcomes of the patient with sinonasal mucosal melanoma: the role of endoscopic resection and postoperative radiotherapy2023
- Author(s)
  Tsushima Nayuta、Kano Satoshi、Yasuda Koichi、Suzuki Takayoshi、Hamada Seijiro、Nakamaru Yuji、Suzuki Masanobu、Uchinami Yusuke、Aoyama Hidefumi、Homma Akihiro
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 28 Issue: 9 Pages: 1218-1226
- DOI
  10.1007/s10147-023-02368-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-19K18754
[Journal Article] Schlafen family member 11 indicates favorable prognosis of patients with head and neck cancer following platinum-based chemoradiotherapy2023
- Author(s)
  Hamada Seijiro、Kano Satoshi、Murai Junko、Suzuki Takayoshi、Tsushima Nayuta、Mizumachi Takatsugu、Suzuki Masanobu、Takashima Tsuyoshi、Taniyama Daiki、Sakamoto Naoya、Fujioka Yoichiro、Ohba Yusuke、Homma Akihiro
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 978875-978875
- DOI
  10.3389/fonc.2022.978875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PLANNED-20H05872, KAKENHI-PROJECT-22KJ2201, KAKENHI-PROJECT-19K09883, KAKENHI-PROJECT-21K19347, KAKENHI-PUBLICLY-21H00413
[Journal Article] Mental workload during endoscopic sinus surgery is associated with surgeons’ skill levels2023
- Author(s)
  Suzuki Masanobu、Miyaji Kou、Matoba Kotaro、Abe Takashige、Nakamaru Yuji、Watanabe Ryosuke、Suzuki Takayoshi、Nakazono Akira、Konno Atsushi、Hinder Dominik、Psaltis A. J.、Wormald P. J.、Homma Akihiro
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 10 Pages: 1090743-1090743
- DOI
  10.3389/fmed.2023.1090743
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-23H00480
[Journal Article] Nasal irrigation improving nasal obstruction and QoL of patients: two cases of HHT after nasal dermoplasty2023
- Author(s)
  Takeda Hideaki、Suzuki Masanobu、Nakamaru Yuji、Kimura Shogo、Nakazono Akira、Honma Aya、Homma Akihiro
- Journal Title
  
  JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY
  
  Volume: 32 Issue: 3 Pages: 299-303
- DOI
  10.5106/jjshns.32.299
- ISSN
  1349-581X, 1884-474X
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444
[Journal Article] TRIM27 expression is associated with poor prognosis in sinonasal mucosal melanoma2023
- Author(s)
  Kimura S、Suzuki M、Nakamaru Y、Kano S、Watanabe M、Honma A、Nakazono A、Tsushima N、Hatakeyama S、Homma A
- Journal Title
  
  Rhinology Journal
  
  Volume: - Issue: 0 Pages: 0-0
- DOI
  10.4193/rhin22.405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02690, KAKENHI-PROJECT-18K16871, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-22K19415, KAKENHI-PROJECT-21H02674
[Journal Article] Clinical Characteristics of Patients and Factors Associated with Switching Biologics in Asthma2022
- Author(s)
  Matsumoto-Sasaki Machiko、Simizu Kaoruko、Suzuki Masanobu、Suzuki Masaru、Kimura Hirokazu、Nakamaru Yuji、Ito Yoichi M、Homma Akihiro、Konno Satoshi
- Journal Title
  
  Journal of Asthma and Allergy
  
  Volume: Volume 15 Pages: 187-195
- DOI
  10.2147/jaa.s348513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-18K16871
[Journal Article] Repetitive simulation training with novel 3D‐printed sinus models for functional endoscopic sinus surgeries2022
- Author(s)
  Suzuki Masanobu、Miyaji Kou、Watanabe Ryosuke、Suzuki Takayoshi、Matoba Kotaro、Nakazono Akira、Nakamaru Yuji、Konno Atsushi、Psaltis Alkis James、Abe Takashige、Homma Akihiro、Wormald Peter‐John
- Journal Title
  
  Laryngoscope Investigative Otolaryngology
  
  Volume: 7 Issue: 4 Pages: 943-954
- DOI
  10.1002/lio2.873
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-18K16871
[Journal Article] Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases2021
- Author(s)
  Suzuki Masanobu、Suzuki Takayoshi、Watanabe Masashi、Hatakeyama Shigetsugu、Kimura Shogo、Nakazono Akira、Honma Aya、Nakamaru Yuji、Vreugde Sarah、Homma Akihiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 70 Issue: 2 Pages: 190-200
- DOI
  10.1016/j.alit.2020.09.007
- NAID
  130008024307
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-19H05280, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-18KK0444
[Journal Article] Metallothionein-3 is a clinical biomarker for tissue zinc levels in nasal mucosa2021
- Author(s)
  Suzuki Masanobu、Ramezanpour Mahnaz、Cooksley Clare、Ogi Kazuhiro、Psaltis Alkis J.、Nakamaru Yuji、Homma Akihiro、Wormald Peter-John、Vreugde Sarah
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 48 Issue: 5 Pages: 890-897
- DOI
  10.1016/j.anl.2021.01.019
- Data Source
  KAKENHI-PROJECT-18KK0444
[Journal Article] TLR Signals in Epithelial Cells in the Nasal Cavity and Paranasal Sinuses2021
- Author(s)
  Suzuki Masanobu、Cooksley Clare、Suzuki Takayoshi、Ramezanpour Mahnaz、Nakazono Akira、Nakamaru Yuji、Homma Akihiro、Vreugde Sarah
- Journal Title
  
  Frontiers in Allergy
  
  Volume: 2 Pages: 1-11
- DOI
  10.3389/falgy.2021.780425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16871
[Journal Article] Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells2021
- Author(s)
  Nakazono Akira、Nakamaru Yuji、Ramezanpour Mahnaz、Kondo Takeshi、Watanabe Masashi、Hatakeyama Shigetsugu、Kimura Shogo、Honma Aya、Wormald P. J.、Vreugde Sarah、Suzuki Masanobu、Homma Akihiro
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 11 Pages: 655666-655666
- DOI
  10.3389/fcimb.2021.655666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-21H02690, KAKENHI-PROJECT-18K16871, KAKENHI-PROJECT-19K18718, KAKENHI-PROJECT-18KK0444
[Journal Article] The Quantification of Extracellular Trap Cell Death-Derived Products as Diagnostic Biomarkers for Otitis Media With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis and Eosinophilic Otitis Media2021
- Author(s)
  Morita Shinya、Nakamaru Yuji、Fukuda Atsushi、Fujiwara Keishi、Suzuki Masanobu、Hoshino Kimiko、Honma Aya、Homma Akihiro
- Journal Title
  
  Otology & Neurotology
  
  Volume: 43 Issue: 3 Pages: e337-e343
- DOI
  10.1097/mao.0000000000003431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09744, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-18K16871
[Journal Article] Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity.2019
- Author(s)
  Li J, Ramezanpour M, Fong SA, Cooksley C, Murphy J, Suzuki M, Psaltis AJ, Wormald PJ, Vreugde S.
- Journal Title
  
  Front Cell Infect Microbiol.
  
  Volume: 9
- DOI
  10.3389/fcimb.2019.00038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16871
[Journal Article] Spontaneous regression of swollen submandibular glands in IgG4-related disease.2019
- Author(s)
  Masanobu Suzuki, Yuji Nakamaru, Dai Takagi, Aya Honma, Takayoshi Suzuki, Emi Takakuwa, Shinya Morita, Sarah Vreugde, Akihiro Homma
- Journal Title
  
  Allergy and Rhinology
  
  Volume: 10
- DOI
  10.1177/2152656718816738
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16871, KAKENHI-PROJECT-18KK0444
[Journal Article] Sirtuin-1 Controls Poly (I:C)?Dependent Matrix Metalloproteinase 9 Activation in Primary Human Nasal Epithelial Cells2018
- Author(s)
  Suzuki Masanobu、Ramezanpour Mahnaz、Cooksley Clare、Li Jian、Nakamaru Yuji、Homma Akihiro、Psaltis Alkis、Wormald Peter-John、Vreugde Sarah
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 59 Issue: 4 Pages: 500-510
- DOI
  10.1165/rcmb.2017-0415oc
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16871
[Presentation] Low labile zinc level in nasal mucosa inhibits collagen production in fibroblast.2019
- Author(s)
  鈴木　正宣
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0444
[Presentation] Mucosal zinc deficiency characterises nasal polyps and inhibits collagen production in nasal fibroblasts in vitro2019
- Author(s)
  Masanobu Suzuki
- Organizer
  5th Congress of European ORL-HNS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16871
[Presentation] 鼻粘膜上皮細胞においてSIRT-1は PolyICに誘導されるMMP9を負に制御する。2018
- Author(s)
  鈴木正宣、中丸裕爾、髙木大、本間あや、 P.J. Wormald, Sarah Vreugde, 本間明宏
- Organizer
  第36回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-17H06491
[Presentation] SIRT-1 modifies MMP9 in primary nasal epithelial cells under inflammatory condition.2018
- Author(s)
  Masanobu Suzuki, Mahnaz Ramezanpour, Clare Cooksley, Jian Li, Yuji Nakamaru, Akihiro Homma, P.J. Wormald, and Sarah Vreugde
- Organizer
  37th Congress of the International Society of Inflammation and Allergy of the Nose
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16871
[Presentation] MMP9 regulation in primary human nasal epithelial cells by activated innate immune system2018
- Author(s)
  Masanobu Suzuki, Yuji Nakamaru, Dai Takagi, Aya Honma, Takayoshi Suzuki, Mahnaz Ramezanpour, Sarah Vreugde, and Akihiro Homma
- Organizer
  第67回日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K16871
[Presentation] MMP9 regulation by SIRT-1 in sinonasal epithelium.2018
- Author(s)
  Masanobu Suzuki, Mahnaz Ramezanpour, Clare Cooksley, Jian Li, Yuji Nakamaru, Akihiro Homma, P.J. Wormald, and Sarah Vreugde
- Organizer
  第119回日耳鼻総会
- Data Source
  KAKENHI-PROJECT-18K16871
[Presentation] 鼻粘膜上皮細胞での自然免疫シグナルによるMMP9の発現誘導2017
- Author(s)
  鈴木　正宣、中丸　裕爾、高木　大、本間　あや、 Sarah Vreugde、P.J. Wormald、本間　明宏
- Organizer
  第56回日本鼻科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-17H06491
[Presentation] SIRT-1 Negatively Regulated Poly(I:C)-induced MMP9 in Primary Human Nasal Epithelial Cells.2017
- Author(s)
  Masanobu Suzuki, Mahnaz Ramezanpour, Clare Cooksley, Jian Li, Yuji Nakamaru, Akihiro Homma, P.J. Wormald, and Sarah Vreugd
- Organizer
  Rhinology World Congress Hong Kong 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06491

1. 渡部昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 森田真也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Masanobu 鈴木 正宣

Research Projects

Research Products

Co-Researchers

Type2炎症による鼻粘膜支持組織への影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞内亜鉛とTGF-βシグナル制御による好酸球性副鼻腔炎の新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanisms of cytokines in ECRSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

好酸球性副鼻腔炎の根治を施行したSIRT-1活性化剤の基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Antibiofilm Strategies2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Targeted next-generation sequencing of Japanese patients with sinonasal mucosal melanomas identifies frequent NRAS and CTNNB1 mutations2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment outcomes of the patient with sinonasal mucosal melanoma: the role of endoscopic resection and postoperative radiotherapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Schlafen family member 11 indicates favorable prognosis of patients with head and neck cancer following platinum-based chemoradiotherapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mental workload during endoscopic sinus surgery is associated with surgeons’ skill levels2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nasal irrigation improving nasal obstruction and QoL of patients: two cases of HHT after nasal dermoplasty2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] TRIM27 expression is associated with poor prognosis in sinonasal mucosal melanoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Characteristics of Patients and Factors Associated with Switching Biologics in Asthma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Repetitive simulation training with novel 3D‐printed sinus models for functional endoscopic sinus surgeries2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases2021

Author(s)

Journal Title

DOI

NAID

Suzuki Masanobu 鈴木正宣

[Presentation] 鼻粘膜上皮細胞での自然免疫シグナルによるMMP9の発現誘導2017