ABE Masanori 阿部雅紀

… Alternative Names

阿部雅紀アベマサノリ

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Researcher Number	70459890
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 日本大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine Except Principal Investigator Basic Section 53040:Nephrology-related
Keywords	Principal Investigator PIポリアミド / USF1 / 糖尿病性腎症 / 創薬 / ポリアミド / 腎臓病 / 糖尿病 / 転写因子 / 間質線維化 / ポドサイト / 糖尿病腎症 / TGF-β1 … More Except Principal Investigator … More PIポリアミド / 多発性嚢胞腎 / 疾患特異的iPS細胞 / 創薬 / オルガノイド / GSK3β / 腎オルガノイド / 糖尿病 / プロテインS / 糖尿病性腎症 / PI ポリアミド / 臨床試験 / エピゲノム / 個別医療 / 遺伝性多発性嚢胞腎 Less

多発性嚢胞腎患者由来腎オルガノイドを用いたGSK3β PIポリアミドの創薬
- Principal Investigator
  
  福田昇
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nihon University
Contribution of USF1 on development of diabetic kidney disease and the drug discovery of PI polyamides to block the USF1 bindingPrincipal Investigator
- Principal Investigator
  
  ABE Masanori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nihon University
Development of the novel gene modulator PI polyamide targeting protein S as a therapeutic agent for diabetes mellitus and diabetic nephropathy
- Principal Investigator
  
  TSUNEMI Akiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nihon University
Functional analysis and investigation of medicines using the disease-specific iPS cell-derived collecting duct cells from ADPKD
- Principal Investigator
  
  OIKAWA Osamu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nihon University
Suppressive effects of pyrrole-imidazole polyamides targeting TGF-beta1 as novel biomedicines on the diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  ABE Masanori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nihon University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Development of gene silencer pyrrole-imidazole polyamides targeting GSK3β for treatment of polycystic kidney diseases.2023
- Author(s)
  Baba S, Fukuda N, Kobayashi H, Tsunemi A, Akiya Y, Matsumoto T, Abe M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 151 Issue: 3 Pages: 148-155
- DOI
  10.1016/j.jphs.2023.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08265, KAKENHI-PROJECT-19K08737, KAKENHI-PROJECT-20K08599
[Journal Article] TWIST1 transcriptionally upregulates complement 3 in glomerular mesangial cells from spontaneously hypertensive rats.2022
- Author(s)
  Otsuki T, Fukuda N, Chen L, Ueno T, Otsuki M, Abe M
- Journal Title
  
  Hypertens Res.
  
  Volume: Jan;45(1) Issue: 1 Pages: 66-74
- DOI
  10.1038/s41440-021-00750-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08599
[Journal Article] Implantation of dedifferentiated fat cells ameliorated antineutrophil cytoplasmic antibody glomerulonephritis by immunosuppression and increases in tumor necrosis factor-stimulated gene-6.2022
- Author(s)
  Utsunomiya K, Maruyama T, Shimizu S, Matsumoto T, Endo M, Kobayashi H, Kano K, Abe M, Fukuda N.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: 13; 319. Issue: 1 Pages: 319-319
- DOI
  10.1186/s13287-022-03014-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08265, KAKENHI-PROJECT-20H03581, KAKENHI-PROJECT-20K08599
[Journal Article] Twist-related protein 1 induces epithelial-mesenchymal transition and renal fibrosis through the upregulation of complement 3.2022
- Author(s)
  Otsuki T, Fukuda N, Chen L, Tsunemi A, Abe M.
- Journal Title
  
  PLoS One.
  
  Volume: 17(8):e0272917 Issue: 8 Pages: e0272917-e0272917
- DOI
  10.1371/journal.pone.0272917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08265, KAKENHI-PROJECT-19K08737, KAKENHI-PROJECT-20K08599
[Journal Article] Transcriptional Suppression of Diabetic Nephropathy with Novel Gene Silencer Pyrrole-Imidazole Polyamides Preventing USF1 Binding to the TGF-β1 Promoter2021
- Author(s)
  Okamura Makiyo、Fukuda Noboru、Horikoshi Shu、Kobayashi Hiroki、Tsunemi Akiko、Akiya Yurie、Endo Morito、Matsumoto Taro、Abe Masanori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 9 Pages: 4741-4741
- DOI
  10.3390/ijms22094741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08599, KAKENHI-PROJECT-21K08265
[Journal Article] Contribution of TGF-β1 and Effects of Gene Silencer Pyrrole-Imidazole Polyamides Targeting TGF-β1 in Diabetic Nephropathy.2020
- Author(s)
  Horikoshi S, Fukuda N, Tsunemi A, Okamura M, Otsuki, Endo M, Abe M.
- Journal Title
  
  Molecules
  
  Volume: Feb 20;25(4) Issue: 4 Pages: 950-950
- DOI
  10.3390/molecules25040950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09716
[Journal Article] Glycemic control and survival in peritoneal dialysis patients with diabetes: A 2-year nationwide cohort study.2019
- Author(s)
  Abe M, Hamano T, Hoshino J, Wada A, Nakai S, Masakane I.
- Journal Title
  
  Sci Rep.
  
  Volume: Mar 1;9(1) Issue: 1 Pages: 3320-3320
- DOI
  10.1038/s41598-019-39933-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09716
[Journal Article] Canagliflozin Improves Erythropoiesis in Diabetes Patients with Anemia of Chronic Kidney Disease.2019
- Author(s)
  Maruyama T, Takashima H, Oguma H, Nakamura Y, Ohno M, Utsunomiya K, Furukawa T, Tei R, Abe M.
- Journal Title
  
  Diabetes Technol Ther.
  
  Volume: Dec;21(12) Issue: 12 Pages: 713-720
- DOI
  10.1089/dia.2019.0212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09716
[Journal Article] Predictors of outcomes in patients on peritoneal dialysis: A 2-year nationwide cohort study.2019
- Author(s)
  Abe M, Hamano T, Hoshino J, Wada A, Nakai S, Hanafusa N, Masakane I, Nitta K, Nakamoto H
- Journal Title
  
  Sci Rep.
  
  Volume: Mar 8;9(1) Issue: 1 Pages: 3967-3967
- DOI
  10.1038/s41598-019-40692-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09716
[Journal Article] Preclinical Study of DNA-Recognized Peptide Compound Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Progressive Renal Diseases in the Common Marmoset.2019
- Author(s)
  Otsuki M, Fukuda N, Inoue T, Mineshige T, Otsuki T, Horikoshi S, Endo M, Abe M.
- Journal Title
  
  Molecules.
  
  Volume: Sep 1;24(17) Issue: 17 Pages: 3178-3178
- DOI
  10.3390/molecules24173178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09716
[Journal Article] Visualization of Blood Glucose Fluctuations Using Continuous Glucose Monitoring in Patients Undergoing Hemodialysis2018
- Author(s)
  Mori Katsuhito、Emoto Masanori、Abe Masanori、Inaba Masaaki
- Journal Title
  
  Journal of Diabetes Science and Technology
  
  Volume: 13 Issue: 2 Pages: 413-414
- DOI
  10.1177/1932296818818429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09649, KAKENHI-PROJECT-17K09716
[Patent] 同時にHGF遺伝子発現を増加しTGF-β1遺伝子発現を抑制するピロール・イミダゾールポリアミド2020
- Inventor(s)
  福田　昇、陳　蘭、上野高浩、阿部雅紀
- Industrial Property Rights Holder
  福田　昇、陳　蘭、上野高浩、阿部雅紀
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症へのUSF1阻害PIポリアミドの開発2023
- Author(s)
  秋谷友里恵、福田昇、岡村真喜誉、小林洋輝、堀越周、常見明子、阿部雅紀
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08265
[Presentation] ヒト腎臓オルガノイドから糖尿病性腎症モデルの作成の試み2022
- Author(s)
  秋谷友里恵、福田　昇、小林洋輝、常見明子、大野迪子、阿部雅紀
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08599
[Presentation] ヒト腎臓オルガノイドから糖尿病性腎症モデルの作成の試み2022
- Author(s)
  秋谷友里恵、福田　昇、小林洋輝、常見明子、大野迪子、阿部雅紀
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08265
[Presentation] 常染色体優性多発性嚢胞腎患者の疾患特異的iPS細胞からの腎臓オルガノイドを用いた嚢胞形成の評価2021
- Author(s)
  福田　昇、大野迪子、常見明子、阿部雅紀、松本太郎
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K08599
[Presentation] 常染色体優性多発性嚢胞腎患者の疾患特異的iPS細胞からの腎臓オルガノイドを用いた嚢胞形成の評価2021
- Author(s)
  福田　昇、大野迪子、常見明子、阿部雅紀、松本太郎
- Organizer
  第20回日本再生医療学会総会 Web発表
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] 常染色体多発性嚢胞腎(ADPKD)疾患特異的iPS細胞からの腎臓オルガノイドを用いた嚢胞形成の評価2021
- Author(s)
  大野迪子、福田　昇、常見明子、Chen Lan、深澤みゆき、阿部雅紀
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08599
[Presentation] 常染色体優性多発性嚢胞腎患者の疾患特異的iPS細胞からの腎臓オルガノイドを用いた嚢胞形成の評価2021
- Author(s)
  福田　昇、大野迪子、常見明子、阿部雅紀、松本太郎
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K08265
[Presentation] 常染色体多発性嚢胞腎(ADPKD)疾患特異的iPS細胞からの腎臓オルガノイドを用いた嚢胞形成の評価2021
- Author(s)
  大野迪子、福田　昇、常見明子、Chen Lan、深澤みゆき、阿部雅紀
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08265
[Presentation] 糖尿病性腎症に対する新規バイオ医薬USF1 PIポリアミドの効果2020
- Author(s)
  岡村真喜誉、福田　昇、堀越　周、常見明子、深澤みゆき、阿部雅紀
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08599
[Presentation] ヒトiPS細胞からの多発性嚢胞腎疾患特異的腎臓オルガノイドの作製2020
- Author(s)
  大野迪子、福田　昇、常見明子、Chen Lan、深澤みゆき、阿部雅紀
- Organizer
  第63回日本腎臓学会学術総会 Web発表
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] 疾患特異的iPS細胞からの腎臓オルガノイドを用いた多発性嚢胞腎の個別医療の試み2020
- Author(s)
  福田　昇、大野迪子、常見明子、Chen Lan、深澤みゆき、阿部雅紀
- Organizer
  第19回日本再生医療学会総会 Web発表
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] Current status and strategy for diabetes patients on peritoneal dialysis in Japan.2019
- Author(s)
  .Masanori Abe
- Organizer
  Symposium 10, Asia Pacific Chapter of Meeting of International Society for Peritoneal Dialysis APCM-ISPD 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 多発性嚢胞腎への新規バイオ医薬としてのGSK3βに対するPIポリアミドの開発2019
- Author(s)
  馬場晴志郎、福田昇、常見明子、岡村真喜誉、大野迪子、阿部雅紀
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] Year in Review DM.2019
- Author(s)
  阿部雅紀
- Organizer
  第64回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 透析患者の血糖管理～誰がどのように行っているのか？～.2019
- Author(s)
  阿部雅紀
- Organizer
  第64回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症に対する新規バイオ医薬USF1 PIポリアミドの開発2019
- Author(s)
  岡村真喜誉、福田昇、堀越周、常見明子、深澤みゆき、阿部雅紀
- Organizer
  第42回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] ヒトiPS細胞からの腎臓オルガノイド作製での多発性嚢胞腎への個別医療2019
- Author(s)
  大野迪子、福田　昇、常見明子、Chen Lan、深澤みゆき、阿部雅紀
- Organizer
  第42回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] Induction kidney organoid from disease-specific iPS cells.2019
- Author(s)
  Lan Chen, Noboru Fukuda, Akiko Tsunemi, Sho Tanaka, Asako Oguni, Kosuke Saito, Kyoko Fujiwara, Masanori Abe, Taro Matsumoto
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] Combination of Once Weekly Hemodialysis with Peritoneal Dialysis Is Associated with Lower Mortality Compared with Peritoneal Dialysis Alone: A Longitudinal Study.2019
- Author(s)
  Miho Tagawa, Masanori Abe, Takayuki Hamano, Ikuto Masakane
- Organizer
  ASN Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 多発性嚢胞腎への新規バイオ医薬としてのGSK3βに対するPIポリアミドの開発2019
- Author(s)
  馬場晴志郎、福田　昇、常見明子、大野迪子、阿部雅紀
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] Glycemic control in diabetes patients on dialysis in Japan ~ Is there a "burnt-out diabetes" phenomenon in patients on hemodialysis? ~2019
- Author(s)
  Masanori Abe.
- Organizer
  Korean Society of Nephrology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] The Target Glycated Albumin Level May Differ According to Dialysis Patients' Nutritional Status and Use of Hypoglycemic Agents: A 3-Year Nationwide Cohort Study.2019
- Author(s)
  Junichi Hoshino, Masanori Abe, Takayuki Hamano, Takeshi Hasegawa, Atsushi Wada, Yoshifumi Ubara, Kenmei Takaichi, Shigeru Nakai, Ikuto Masakane, Kosaku Nitta.
- Organizer
  ASN Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症におけるSGLT2阻害薬の腎機能および貧血に対する効果2019
- Author(s)
  高島弘至、丸山高史、鄭立晃、古川哲也、北井真貴、吉田好徳、丸山範晃、阿部雅紀.
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] Current status of CKD patients and strategy for patients on PD in Japan.2019
- Author(s)
  Masanori Abe
- Organizer
  Asia Pacific Chapter of Meeting of International Society for Peritoneal Dialysis APCM-ISPD 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] GSK3βに対する遺伝子制御薬PIポリアミドの多発性嚢胞腎への効果の検討2019
- Author(s)
  馬場晴志郎、福田　昇、常見明子、大野迪子、阿部雅紀
- Organizer
  第42回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-18K08225
[Presentation] 腎臓からみた新たなる糖尿病治療戦略～SGLT2阻害薬の可能性について～.2019
- Author(s)
  阿部雅紀.
- Organizer
  第93回日本糖尿病学会中部地方会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症に対する新規バイオ医薬USF1 PIポリアミドの開発2019
- Author(s)
  岡村真喜誉、福田昇、堀越周、常見明子、深澤みゆき、阿部雅紀
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] Efficacy and safety of canagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetic kidney disease: A randomized open-label prospective trial.2019
- Author(s)
  Takashi Maruyama, Noriaki Maruyama, Hiroyuki Takashima, Ritsukou Tei, Tetsuya Furukawa, Masanori Abe.
- Organizer
  World Congress of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症へのTGF-β1抑制ペプチド化合物PIポリアミドの効果の検討2018
- Author(s)
  堀越周、福田昇、森内正理、大月伯恭、上野高浩、遠藤守人、阿部雅紀
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症へのTGF-β1抑制ペプチド化合物PIポリアミドの効果の検討2018
- Author(s)
  堀越周、福田昇、遠藤守人、上野高浩、阿部雅紀
- Organizer
  第41回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 高糖条件でTGF-β1 発現を増加する転写因子USF1 に対するPI ポリアミドの開発2018
- Author(s)
  岡村真喜誉、福田　昇、堀越　周、常見明子、深澤みゆき、阿部雅紀
- Organizer
  第30回日本糖尿病性腎症研究会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] TGFβ1発現を抑制するUSF1に対するペプチド化合物PIポリアミドの作用の検討2018
- Author(s)
  岡村真喜誉、福田　昇、堀越　周、常見明子、深澤みゆき、阿部雅紀
- Organizer
  第41回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症へのTGF-β1抑制ペプチド化合物PIポリアミドの効果の検討2018
- Author(s)
  堀越周、福田昇、森内正理、大月伯恭、上野高浩、遠藤守人、阿部雅紀
- Organizer
  第22回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] TGFβ1発現を抑制するUSF1に対するPIポリアミドの効果の検討2018
- Author(s)
  岡村真喜誉、福田　昇、堀越　周、常見明子、深澤みゆき、阿部雅紀.
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症に於けるTGF-β1の関与と新規ペプチド医薬PIポリアミドの抑制効果2017
- Author(s)
  堀越　周、福田　昇、根岸英理子、森内正理、大月伯恭、常見明子、上野高浩、遠藤守人、阿部雅紀
- Organizer
  第53回高血圧関連疾患モデル学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] マーモセット人選以下モデルの確立とヒトTGF-β1に対する新規遺伝子制御薬PIポリアミドの創薬2017
- Author(s)
  森内正理、福田　昇、井上貴史、大月伯恭、堀越　周、常見明子、上野高浩、岡田一義、阿部雅紀
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] マーモセットにおける腎線維化モデルの確立とヒトTGF-β1に対する新規遺伝子制御薬PIポリアミドの効果2017
- Author(s)
  森内正理、福田　昇、井上貴史、峰重隆幸、大月伯恭、堀越　周、常見明子、深澤みゆき、阿部雅紀
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病腎症の進展におけるTGF-β1の関与と新規遺伝子制御薬PIポリアミドの効果2017
- Author(s)
  堀越　周、福田　昇、根岸英理子、森内正理、大月伯恭、上野高浩、菱木三佳乃、遠藤守人、阿部雅紀
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病腎症におけるTGF-β1の関与と新規遺伝子制御薬PIポリアミドの抑制効果2017
- Author(s)
  堀越　周、福田　昇、遠藤守人、小林洋樹、森内正理、大月伯恭、上野高浩、阿部雅紀
- Organizer
  心血管代謝週間CVMW2017（第21回日本心血管内分泌代謝学会学術総会）
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] マーモセットでの腎繊維化モデルの確立とヒトTGF-β1に対するPIポリアミドの創薬開発2017
- Author(s)
  森内正理、福田　昇、中井茂樹、井上貴史、峰重隆幸、大月伯恭、堀越　周、遠藤守人、阿部雅紀
- Organizer
  第53回高血圧関連疾患モデル学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716
[Presentation] 糖尿病性腎症におけるTGF-β1の関与と新規遺伝子制御薬PIポリアミドの高価の検討2017
- Author(s)
  堀越　周、福田　昇、根岸英理子、森内正理、大月伯恭、上野高浩、遠藤守人、阿部雅紀
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09716

1. 福田昇 (40267050)

# of Collaborated Projects: 4 results

# of Collaborated Products: 38 results
2. 松本宜明 (10199896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. OIKAWA Osamu (60813590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TSUNEMI Akiko (90646035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 上野高浩 (40386008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORI Katsuhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ABE Masanori 阿部 雅紀

阿部 雅紀 アベ マサノリ

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多発性嚢胞腎患者由来腎オルガノイドを用いたGSK3β PIポリアミドの創薬

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Contribution of USF1 on development of diabetic kidney disease and the drug discovery of PI polyamides to block the USF1 bindingPrincipal Investigator

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Development of the novel gene modulator PI polyamide targeting protein S as a therapeutic agent for diabetes mellitus and diabetic nephropathy

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Functional analysis and investigation of medicines using the disease-specific iPS cell-derived collecting duct cells from ADPKD

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Suppressive effects of pyrrole-imidazole polyamides targeting TGF-beta1 as novel biomedicines on the diabetic nephropathyPrincipal Investigator

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[Journal Article] Development of gene silencer pyrrole-imidazole polyamides targeting GSK3β for treatment of polycystic kidney diseases.2023

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[Journal Article] TWIST1 transcriptionally upregulates complement 3 in glomerular mesangial cells from spontaneously hypertensive rats.2022

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[Journal Article] Implantation of dedifferentiated fat cells ameliorated antineutrophil cytoplasmic antibody glomerulonephritis by immunosuppression and increases in tumor necrosis factor-stimulated gene-6.2022

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[Journal Article] Twist-related protein 1 induces epithelial-mesenchymal transition and renal fibrosis through the upregulation of complement 3.2022

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[Journal Article] Transcriptional Suppression of Diabetic Nephropathy with Novel Gene Silencer Pyrrole-Imidazole Polyamides Preventing USF1 Binding to the TGF-β1 Promoter2021

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[Journal Article] Contribution of TGF-β1 and Effects of Gene Silencer Pyrrole-Imidazole Polyamides Targeting TGF-β1 in Diabetic Nephropathy.2020

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[Journal Article] Glycemic control and survival in peritoneal dialysis patients with diabetes: A 2-year nationwide cohort study.2019

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[Journal Article] Canagliflozin Improves Erythropoiesis in Diabetes Patients with Anemia of Chronic Kidney Disease.2019

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[Journal Article] Predictors of outcomes in patients on peritoneal dialysis: A 2-year nationwide cohort study.2019

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ABE Masanori 阿部雅紀

阿部雅紀アベマサノリ

[Presentation] 疾患特異的iPS細胞からの腎臓オルガノイドを用いた多発性嚢胞腎の個別医療の試み2020