tsuchiya atsunori 土屋淳紀

… Alternative Names

Tsuchiya Atsunori 土屋淳紀

TSUCHIYA Ataunori 土屋淳紀

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Researcher Number	70464005
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 新潟大学, 医歯学系, 准教授 2018 – 2023: 新潟大学, 医歯学総合病院, 講師 2017: 新潟大学, 医歯学総合病院, その他 2015 – 2017: 新潟大学, 医歯学総合病院, 助教 2016: 新潟大学, 医歯学総合病院, 特任助教 2008 – 2011: Niigata University, 医歯学総合病院, 医員
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 49050:Bacteriology-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator 細胞外小胞 / 肝硬変 / マクロファージ / エクソソーム / 間葉系幹細胞 / NCAM / 肝細胞癌 / CXCR4 / 肝幹前駆細胞 / 肝再生 … More / SDF-1 / 大腸菌 / 外膜小胞 / miRNA / 急性肝障害 / 幹前駆細胞 / 腫瘍マーカー / 肝前駆細胞マーカー / DLK1 / CK19 / EpCAM / 肝前駆細胞 / FGF / 140Kda NCAM / Soluble NCAM / HCC with progenitor features / 肝線維化 / soluble NCAM / CD11b / floxマウス / ductular reaction / 肝臓 / VEGF / Mxマウス / ALT / マウス … More Except Principal Investigator エクソソーム / 間葉系幹細胞 / 細胞外小胞 / 非アルコール性脂肪肝炎 / 線維化 / NASH / トリアムシノロン / 内視鏡的粘膜下層剥離術 / 食道狭窄 / 老化 / 肝硬変 / HABR / 心肝臓器連関 / 小児移行期医療 / うっ血性肝不全 / うっ血肝 / フォンタン術後 / 心肝連関 / マイトファジー / 老化細胞 / 膵癌モデル / HGDラット / エクソソームタンパクEps8 / HGD法 / HGD法ラット膵癌モデル / プロテオーム解析 / タンパク / 蛋白発現 / ラット膵癌モデル / ハイドロダイナミック法 / 膵癌 / miRNA / オープンフィールド / マイオカイン / GlyT1 / SLC6A9 / 肝性脳症 / サルコぺニア / 肝筋相関 / サルコペニア / 肝癌 / 肝細胞癌 / 腫瘍 / 内視鏡的粘膜切除 / コラゲナーゼ / 瘢痕狭窄 / 痔瘻モデル / 瘻孔モデル / ESD / 皮膚瘻孔モデル / マイクロダイセクション / ピロリ菌 / 胃がん / 幽門腺化生 / CDX2 / MUC6 / 腸上皮化生 / H.pylori / 慢性胃炎 / 胃癌 / 発癌モデル / SGLT2阻害剤 / メダカモデル / ハイドロゲル / 生体吸収性ゼラチンハイドロゲルシート / 早期食道癌 / 徐放化 / ハイドロゲルシート / 食道癌 / 細胞・組織 / トランスレーショナルリサーチ / 再生医学 / 移植・再生医療 / 線維化改善 / 肝再生 / 間葉系細胞 / 再生医療 / ライブイメージング / マクロファージ / 細胞療法 Less

Extracellular Vesicles Regulate Progressive Congestive Hepatopathy due to Heart Failure
- Principal Investigator
  
  上村博輝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Development of liver regeneration therapy using super exosomes with multiple and high volume protein delivery systemsPrincipal Investigator
- Principal Investigator
  
  Tsuchiya Atsunori
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Niigata University
Elucidation of the Mechanism of Regenerative Insufficiency in Advanced Liver Cirrhosis Caused by Intestinal Bacterial Extracellular Vesicles and Development of Prevention and Treatment MethodsPrincipal Investigator
- Principal Investigator
  
  土屋淳紀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Niigata University
Identification of malignant extracellular vesicles of liver origin that regulate nonalcoholic steatohepatitis and the development of the treatment
- Principal Investigator
  
  寺井崇二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Pancreatic cancer biomarker research by the exosome proteome analysis of the HGD rat pancreatic cancer model
- Principal Investigator
  
  林和直
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Elucidation of Extracellular Vesicles Contributing Liver and Muscle Linkage
- Principal Investigator
  
  Kamimura Hiroteru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
The study of emergence of cancerous gland in chronic gastritis through three dimensional histological structure and genetic analysis
- Principal Investigator
  
  Yagi Kazuyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Efficacy of mesenchymal stem cell for prevention of esophageal stricture after endoscopic submucosal dissection
- Principal Investigator
  
  Hashimoto Satoru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Development of a treatment to improve fibrosis and elucidation of carcinogenesis mechanisms in improved NASH model MC4RKO mice
- Principal Investigator
  
  Terai Shuji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Development of novel anti-inflammatory therapy using mesenchymal stem cellsPrincipal Investigator
- Principal Investigator
  
  Tsuchiya Atsunori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Efficacy of gelatin hydrogels incorporating triamcinolone acetonide for prevention of esohageal fibrosis after endoscopic submucosal dissection
- Principal Investigator
  
  Satoru Hashimoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Development of Medaka NASH Model and Hepatocarcinogenesis
- Principal Investigator
  
  Terai Shuji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Analysis of the factors of malignant behavior in hepatic progenitor cell marker expressing hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Tsuchiya Atsunori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Basic research to develop next generation cell therapy for improvement of liver fibrosis.
- Principal Investigator
  
  TERAI Shuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
A study of liver regeneration and new treatment of hepatocellular carcinoma based on the understanding of hepatic stem/progenitor cells for building a base and development.Principal Investigator
- Principal Investigator
  
  TSUCHIYA Atsunori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Aiming for the improvement of regenerative ability of the liver from hepatic stem cells by analyzing the role of SDF-1Principal Investigator
- Principal Investigator
  
  TSUCHIYA Ataunori
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University

[Book] 【慢性肝臓病の克服を目指して】肝臓リハビリテーションと再生医療の開発状況日本内科学会雑誌2024
- Author(s)
  上村博輝 , 土屋淳紀 , 寺井崇二
- Total Pages
  6
- Publisher
  (一社)日本内科学会
- Data Source
  KAKENHI-PROJECT-23K07372
[Book] 小児期発症慢性肝疾患における移行期医療の現状と課題-小児と成人のダイアログ-】NAFLD Pediatric fatty liver disease(PeFLD)における概説と成人との比較(肝組織学的検討を含めて) 小児と成人の相違2021
- Author(s)
  上村博輝, 山崎文紗子, 佐藤毅昂, 薛徹, 土屋淳紀, 上村顕也, 高村昌昭, 寺井崇二, 長崎啓祐, 斎藤昭彦, 梅津哉
- Total Pages
  15
- Publisher
  (株)アークメディア
- Data Source
  KAKENHI-PROJECT-20K08326
[Book] Springer2015
- Author(s)
  Dexi Liu, Atsunori Tsuchiya, Stuart J. Forbes, Taro Takami, Masahiro Ohira, Noriho Iida, Hiroaki Mizukami, Narumi Uno, Kenya Kamimura, Takashi Aoi, Matthias Renner, Hanayuki Okura, Akifumi Matsuyama, Mamoru Kokubo, james E. Akers, Junichi Mineno, Takeshi Suda, Shuji Terai.
- Total Pages
  185
- Publisher
  Gene Therapy and Cell Therapy Through the Liver: Current Aspects and Future Prospects
- Data Source
  KAKENHI-PROJECT-26293175
[Book] Gene Therapy and Cell Therapy Through the Liver2015
- Author(s)
  Tsuchiya A, Forbes SJ
- Total Pages
  9
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K08990
[Journal Article] Escherichia coli-derived outer-membrane vesicles induce immune activation and progression of cirrhosis in mice and humans2023
- Author(s)
  Kazuki Natsui, Atsunori Tsuchiya, Risa Imamiya, Mayuko Osada, Yui Ishii, Yohei Koseki, Nobutaka Takeda, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida, Riuko Ohashi, Yiwei Ling, Koji Ueda, Nobuko Moritoki, Kazuhiro Sato, Takahiro Nakajima, Yoshinori Hasegawa, Shujiro Okuda, Shinsuke Shibata, Shuji Terai
- Journal Title
  
  Liver Int
  
  Volume: 43(5) Issue: 5 Pages: 1126-1140
- DOI
  10.1111/liv.15539
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-20K07481, KAKENHI-PROJECT-23K24128
[Journal Article] Analysis of drug‐induced liver‐related adverse event trend reporting between 1997 and 20192023
- Author(s)
  Kamimura Hiroteru、Setsu Toru、Kimura Naruhiro、Miyazawa Makoto、Kaneko Shota、Kamimura Kenya、Tsuchiya Atsunori、Uesawa Yoshihiro、Terai Shuji
- Journal Title
  
  Hepatology Research
  
  Volume: in　press Issue: 6 Pages: 556-568
- DOI
  10.1111/hepr.13883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08326
[Journal Article] Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis2023
- Author(s)
  Takeda Nobutaka、Tsuchiya Atsunori、Mito Masaki、Natsui Kazuki、Natusi Yui、Koseki Yohei、Tomiyoshi Kei、Yamazaki Fusako、Yoshida Yuki、Abe Hiroyuki、Sano Masayuki、Kido Taketomo、Yoshioka Yusuke、Kikuta Junichi、Itoh Tohru、Nishimura Ken、Ishii Masaru、Ochiya Takahiro、Miyajima Atsushi、Terai Shuji
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1 Pages: 48-48
- DOI
  10.1186/s41232-023-00299-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19423, KAKENHI-PROJECT-22K19933, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02518, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K24128
[Journal Article] Development and validation of machine learning model for predicting treatment responders in patients with primary biliary cholangitis2023
- Author(s)
  Kimura Naruhiro、Takahashi Kazuya、Setsu Toru、Horibata Yusuke、Kaneko Yusuke、Miyazaki Haruka、Ogawa Kohei、Kawata Yuzo、Sakai Norihiro、Watanabe Yusuke、Abe Hiroyuki、Kamimura Hiroteru、Sakamaki Akira、Yokoo Takeshi、Kamimura Kenya、Tsuchiya Atsunori、Terai Shuji
- Journal Title
  
  Hepatology Research
  
  Volume: 54 Issue: 1 Pages: 67-77
- DOI
  10.1111/hepr.13966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07372
[Journal Article] Navitoclax improves acute‐on‐chronic liver failure by eliminating senescent cells in mice2023
- Author(s)
  Watanabe Yusuke、Abe Hiroyuki、Kimura Naruhiro、Arao Yoshihisa、Ishikawa Natsuki、Yuichiro Maeda、Setsu Toru、Sakamaki Akira、Kamimura Hiroteru、Yokoo Takeshi、Kamimura Kenya、Tsuchiya Atsunori、Terai Shuji
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 5 Pages: 460-472
- DOI
  10.1111/hepr.13879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-21K15993
[Journal Article] Use of a Deep Learning Approach for the Sensitive Prediction of Hepatitis B Surface Antigen Levels in Inactive Carrier Patients2022
- Author(s)
  Kamimura Hiroteru、Nonaka Hirofumi、Mori Masaya、Kobayashi Taichi、Setsu Toru、Kamimura Kenya、Tsuchiya Atsunori、Terai Shuji
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 2 Pages: 387-387
- DOI
  10.3390/jcm11020387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-20K08379
[Journal Article] Small extracellular vesicles and liver diseases: From diagnosis to therapy2022
- Author(s)
  Tsuchiya Atsunori、Natsui Kazuki、Ishii Yui、Koseki Yohei、Takeda Nobutaka、Tomiyoshi Kei、Yamazaki Fusako、Yoshida Yuki、Terai Shuji
- Journal Title
  
  World Journal of Hepatology
  
  Volume: 14 Issue: 7 Pages: 1307-1318
- DOI
  10.4254/wjh.v14.i7.1307
- Data Source
  KAKENHI-PROJECT-22K19933
[Journal Article] Basic points to consider regarding the preparation of extracellular vesicles and their clinical applications in Japan2022
- Author(s)
  Tsuchiya Atsunori、Terai Shuji、Horiguchi Ikki、Homma Yasuhiro、Saito Atsuhiro、Nakamura Norimasa、Sato Yoji、Ochiya Takahiro、Kino-oka Masahiro
- Journal Title
  
  Regenerative Therapy
  
  Volume: 21 Pages: 19-24
- DOI
  10.1016/j.reth.2022.05.003
- Data Source
  KAKENHI-PROJECT-22K19933
[Journal Article] Paris II and Rotterdam criteria are the best predictors of outcomes in patients with primary biliary cholangitis in Japan2021
- Author(s)
  Kimura N, Takamura M, Takeda N, Watanabe Y, Arao Y, Takatsuna M, Takeuchi S, Abe H, Setsu T, Kamimura H, Sakamaki A, Kamimura K, Tsuchiya A, and Terai S.
- Journal Title
  
  Hepatology International
  
  Volume: 15 Issue: 2 Pages: 437-443
- DOI
  10.1007/s12072-021-10163-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08417, KAKENHI-PROJECT-20K08326
[Journal Article] Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis2021
- Author(s)
  Takeuchi S, Tsuchiya A, Iwasawa T、Nojiri S、Watanabe T、Ogawa M、Yoshida T、Fujiki K、Koui Y、Kido T、Yoshioka Y、Fujita M、Kikuta J、Itoh T、Takamura M、Shirahige K、Ishii M、Ochiya T、Miyajima A、Terai S
- Journal Title
  
  npj Regenerative Medicine
  
  Volume: 6 Issue: 1
- DOI
  10.1038/s41536-021-00132-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21384, KAKENHI-PROJECT-18K07903, KAKENHI-PROJECT-19H03636, KAKENHI-PROJECT-21H02710
[Journal Article] Molecular Mechanisms and Treatment of Sarcopenia in Liver Disease: A Review of Current Knowledge2021
- Author(s)
  Kamimura Hiroteru、Sato Takeki、Natsui Kazuki、Kobayashi Takamasa、Yoshida Tomoaki、Kamimura Kenya、Tsuchiya Atsunori、Murayama Toshiko、Yokoyama Junji、Kawai Hirokazu、Takamura Masaaki、Terai Shuji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1425-1425
- DOI
  10.3390/ijms22031425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08326
[Journal Article] Relationship between detection of hepatitis B virus in saliva and periodontal disease in hepatitis B virus carriers in Japan， Journal of Infection and Chemotherapy2021
- Author(s)
  Kamimura Hiroteru, Jun Watanabe, Tomoyuki Sugano, Junji Kohisa, Hiroyuki Abe, Keny Kamimura, Atsunori Tsuchiya, Masaaki Takamura, Shogo Okoshi, Yoshinari Tanabe, Ritsuo Takagi, Hirofumi Nonaka, Shuji Terai
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: Vol.27, No.3 Issue: 3 Pages: 492-496
- DOI
  10.1016/j.jiac.2020.10.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12116, KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-18K04645, KAKENHI-PROJECT-20K08379
[Journal Article] Pyloric-gland metaplasia may be an origin of cancer and intestinal metaplasia with possible CDX2 expression2021
- Author(s)
  Yagi K, Tsuchiya A, Hashimoto S, Kato T, Onodera O, Terai S
- Journal Title
  
  Gastroenterology Report
  
  Volume: なし Issue: 4 Pages: 1-4
- DOI
  10.1093/gastro/goaa061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08389
[Journal Article] Successful treatment of positive-sense RNA virus coinfection with autoimmune hepatitis using double filtration plasmapheresis2021
- Author(s)
  Kamimura Hiroteru、Kamimura Kenya、Tsuchiya Atsunori、Terai Shuji
- Journal Title
  
  BMJ Case Reports
  
  Volume: 14 Issue: 3 Pages: e236984-e236984
- DOI
  10.1136/bcr-2020-236984
- Data Source
  KAKENHI-PROJECT-20K08326
[Journal Article] Severe steatosis and mild colitis are important for the early occurrence of hepatocellular carcinoma2021
- Author(s)
  Sato Takeki、Tsuchiya Atsunori、Owaki Takashi、Kumagai Masaru、Motegi Satoko、Iwasawa Takahiro、Nojiri Shunsuke、Ogawa Masahiro、Takeuchi Suguru、Watanabe Yusuke、Kawata Yuzo、Kamimura Hiroteru、Terai Shuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 566 Pages: 36-44
- DOI
  10.1016/j.bbrc.2021.05.097
- Data Source
  KAKENHI-PROJECT-19H03636, KAKENHI-PROJECT-20K08326
[Journal Article] The development of mesenchymal stem cell therapy in the present, and the perspective of cell-free therapy in the future2021
- Author(s)
  Watanabe Yusuke、Tsuchiya Atsunori、Terai Shuji
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: 27 Issue: 1 Pages: 70-80
- DOI
  10.3350/cmh.2020.0194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03636, KAKENHI-PROJECT-18K07903
[Journal Article] Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice.2021
- Author(s)
  Nojiri S, Tsuchiya A, Natsui K, Takeuchi S, Watanabe T, Kojima Y, Watanabe Y, Kamimura H, Ogawa M, Motegi S, Iwasawa T, Sato T, Kumagai M, Ishii Y, Kitayama T, Li YT, Ouchi Y, Shimbo T, Takamura M, Tamai K, Terai S
- Journal Title
  
  Inflamm Regen
  
  Volume: 41(1) Issue: 1 Pages: 28-28
- DOI
  10.1186/s41232-021-00177-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03682, KAKENHI-PROJECT-20K08326
[Journal Article] Transcriptomic Dissection of Hepatocyte Heterogeneity: Linking Ploidy, Zonation, and Stem/Progenitor Cell Characteristics2020
- Author(s)
  Katsuda Takeshi、Hosaka Kazunori、Matsuzaki Juntaro、Usuba Wataru、Prieto-Vila Marta、Yamaguchi Tomoko、Tsuchiya Atsunori、Terai Shuji、Ochiya Takahiro
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 9 Issue: 1 Pages: 161-183
- DOI
  10.1016/j.jcmgh.2019.08.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07903
[Journal Article] Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles2020
- Author(s)
  Watanabe Takayuki、Tsuchiya Atsunori、Takeuchi Suguru、Nojiri Shunsuke、Yoshida Tomoaki、Ogawa Masahiro、Itoh Michiko、Takamura Masaaki、Suganami Takayoshi、Ogawa Yoshihiro、Terai Shuji
- Journal Title
  
  Regenerative Therapy
  
  Volume: 14 Pages: 252-261
- DOI
  10.1016/j.reth.2020.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03636, KAKENHI-PROJECT-18K07903, KAKENHI-PUBLICLY-20H05503, KAKENHI-PROJECT-20H03447
[Journal Article] Ten years' experience in Niigata Prefecture Liver Disease Consultation Center2020
- Author(s)
  Kamimura Hiroteru、Setsu Toru、Arao Yoshihisa、Hirokawa Hikaru、Sawaguri Hiromi、Watanabe Fumiko、Komoro Yuko、Sakamaki Akira、Tsuchiya Atsunori、Takamura Masaaki、Ikarashi Masato、Aoyagi Yutaka、Kikuta Rei、Watanabe Kazuhito、Nakayama Hitoshi、Tamura Tsutomu、Terai Shuji
- Journal Title
  
  Kanzo
  
  Volume: 61 Issue: 5 Pages: 245-254
- DOI
  10.2957/kanzo.61.245
- NAID
  130007841505
- ISSN
  0451-4203, 1881-3593
- Year and Date
  2020-05-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08326
[Journal Article] Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases2020
- Author(s)
  Tsuchiya Atsunori、Takeuchi Suguru、Iwasawa Takahiro、Kumagai Masaru、Sato Takeki、Motegi Satoko、Ishii Yui、Koseki Youhei、Tomiyoshi Kei、Natsui Kazuki、Takeda Nobutaka、Yoshida Yuki、Yamazaki Fusako、Kojima Yuichi、Watanabe Yusuke、Kimura Naruhiro、Tominaga Kentaro、Kamimura Hiroteru、Takamura Masaaki、Terai Shuji
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 40 Issue: 1
- DOI
  10.1186/s41232-020-00121-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07903
[Journal Article] Blocking sphingosine 1-phosphate receptor 2 accelerates hepatocellular carcinoma progression in a mouse model of NASH2020
- Author(s)
  Yoshida T, Tsuchiya A, Kumagai M, Takeuchi S, Nojiri S, Watanabe T, Ogawa M, Itoh M, Takamura M, Suganami T, Ogawa Y, Terai S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 530 Issue: 4 Pages: 665-672
- DOI
  10.1016/j.bbrc.2020.07.099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08417, KAKENHI-PROJECT-19H03636, KAKENHI-PUBLICLY-20H05503, KAKENHI-PROJECT-20H03447
[Journal Article] Efficacy of gelatin hydrogels incorporating triamcinolone acetonide for2019
- Author(s)
  Nao Nakajima, Satoru Hashimoto, Hiroki Sato, Kazuya Takahashi, Takuro Nagoya, Kenya Kamimura, Atsunori Tsuchiya, Junji Yokoyama, Yuichi Sato, Hanako Wakatsuki, Masayuki Miyata, Yusuke Akashi, Ryusuke Tanaka, Ken Matsuda, Yasuhiko Tabata, Shuji Terai
- Journal Title
  
  Regenerative Therapy
  
  Volume: 11 Pages: 41-46
- DOI
  10.1016/j.reth.2019.04.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09280, KAKENHI-PROJECT-18K07903, KAKENHI-PROJECT-17K09408
[Journal Article] Early injection of human adipose tissue-derived mesenchymal stem cell after inflammation ameliorates dextran sulfate sodium-induced colitis in mice through the induction of M2 macrophages and regulatory T cells2019
- Author(s)
  Kawata Yuzo、Tsuchiya Atsunori、Seino Satoshi、Watanabe Yusuke、Kojima Yuichi、Ikarashi Shunzo、Tominaga Kentaro、Yokoyama Junji、Yamagiwa Satoshi、Terai Shuji
- Journal Title
  
  Cell and Tissue Research
  
  Volume: 376 Issue: 2 Pages: 257-271
- DOI
  10.1007/s00441-018-02981-w
- Data Source
  KAKENHI-PROJECT-18K07903, KAKENHI-PROJECT-19H03636
[Journal Article] Liver stem cells: Plasticity of the liver epithelium2019
- Author(s)
  Tsuchiya Atsunori、Lu Wei-Yu
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 25 Issue: 9 Pages: 1037-1049
- DOI
  10.3748/wjg.v25.i9.1037
- Data Source
  KAKENHI-PROJECT-18K07903
[Journal Article] Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice2019
- Author(s)
  Watanabe Yusuke、Tsuchiya Atsunori、Seino Satoshi、Kawata Yuzo、Kojima Yuichi、Ikarashi Shunzo、Starkey Lewis Philip J.、Lu Wei-Yu、Kikuta Junichi、Kawai Hirokazu、Yamagiwa Satoshi、Forbes Stuart J.、Ishii Masaru、Terai Shuji
- Journal Title
  
  STEM CELLS Translational Medicine
  
  Volume: 8 Issue: 3 Pages: 271-284
- DOI
  10.1002/sctm.18-0105
- Data Source
  KAKENHI-PROJECT-18K07903
[Journal Article] Mesenchymal stem cells cultured under hypoxic conditions had a greater therapeutic effect on mice with liver cirrhosis compared to those cultured under normal oxygen conditions2019
- Author(s)
  Kojima Yuichi、Tsuchiya Atsunori、Ogawa Masahiro、Nojiri Shunsuke、Takeuchi Suguru、Watanabe Takayuki、Nakajima Kenji、Hara Yukio、Yamashita Junji、Kikuta Junichi、Takamura Masaaki、Ishii Masaru、Terai Shuji
- Journal Title
  
  Regenerative Therapy
  
  Volume: 11 Pages: 269-281
- DOI
  10.1016/j.reth.2019.08.005
- Data Source
  KAKENHI-PROJECT-18K07903, KAKENHI-PROJECT-19H03636
[Journal Article] Mesenchymal stem cell therapies for liver cirrhosis: MSCs as “conducting cells” for improvement of liver fibrosis and regeneration2019
- Author(s)
  Tsuchiya Atsunori、Takeuchi Suguru、Watanabe Takayuki、Yoshida Tomoaki、Nojiri Shunsuke、Ogawa Masahiro、Terai Shuji
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 39 Issue: 1
- DOI
  10.1186/s41232-019-0107-z
- Data Source
  KAKENHI-PROJECT-18K07903, KAKENHI-PROJECT-19H03636
[Journal Article] Effects of Human Adipose Tissue-Derived and Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in a Dextran Sulfate Sodium-Induced Mouse Model2019
- Author(s)
  Ikarashi Shunzo、Tsuchiya Atsunori、Kawata Yuzo、Kojima Yuichi、Watanabe Takayuki、Takeuchi Suguru、Igarashi Katsuhide、Ideta-Otsuka Maky、Oki Katsuyuki、Takamura Masaaki、Terai Shuji
- Journal Title
  
  BioResearch Open Access
  
  Volume: 8 Issue: 1 Pages: 185-199
- DOI
  10.1089/biores.2019.0022
- Data Source
  KAKENHI-PROJECT-19H03636
[Journal Article] Clinical outcome of hepatocellular carcinoma can be predicted by the expression of hepatic progenitor cell markers and serum tumour markers2018
- Author(s)
  Seino Satoshi、Tsuchiya Atsunori、Watanabe Yusuke、Kawata Yuzo、Kojima Yuichi、Ikarashi Shunzo、Yanai Hiroyuki、Nakamura Koji、Kumaki Daisuke、Hirano Masaaki、Funakoshi Kazuhiro、Aono Takashi、Sakai Takeshi、Sakata Jun、Takamura Masaaki、Kawai Hirokazu、Yamagiwa Satoshi、Wakai Toshifumi、Terai Shuji
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 31 Pages: 21844-21860
- DOI
  10.18632/oncotarget.25074
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990
[Journal Article] Status of and candidates for cell therapy in liver cirrhosis: overcoming the "point of no return" in advanced liver cirrhosis.2017
- Author(s)
  Terai S, Tsuchiya A.
- Journal Title
  
  J Gastroenterol.
  
  Volume: Feb;52(2) Issue: 2 Pages: 129-140
- DOI
  10.1007/s00535-016-1258-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-15K08990
[Journal Article] Three Times Repeated Portal Venous Gas after Meals2016
- Author(s)
  Kobayashi T, Tsuchiya A, Suda T, Terai S.
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 7 Pages: 843-845
- DOI
  10.2169/internalmedicine.55.6036
- NAID
  130005141968
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293175
[Journal Article] Stomach Dysfunction Is a Potential Risk Factor for Wernicke's Encephalopathy.2016
- Author(s)
  Nakano O, Tsuchiya A, Yamagiwa S, Terai S.
- Journal Title
  
  Intern Med.
  
  Volume: 55(24) Issue: 24 Pages: 3679-3680
- DOI
  10.2169/internalmedicine.55.7483
- NAID
  130005250350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-15K08990
[Journal Article] Improvement of Pancreatic Tumor-induced NAFLD with Pancrelipase2016
- Author(s)
  Kuraoka N, Tsuchiya A, Suda T, Terai S
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 1 Pages: 89-90
- DOI
  10.2169/internalmedicine.55.5729
- NAID
  130005116798
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990, KAKENHI-PROJECT-26293175
[Journal Article] An Unusual Case of an Extremely Large α-Fetoprotein-Producing Tumor.2016
- Author(s)
  Takahashi K, Tsuchiya A, Terai S.
- Journal Title
  
  Gastroenterology.
  
  Volume: Dec;151(6): Issue: 6 Pages: 1077-1080
- DOI
  10.1053/j.gastro.2016.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-15K08990
[Journal Article] A rare pancreatic tumor that underwent a change in morphology and histopathological2015
- Author(s)
  Seino S, Tsuchiya A, Natsui M
- Journal Title
  
  Gastroenterology
  
  Volume: 150(2) Issue: 2 Pages: e11-e13
- DOI
  10.1053/j.gastro.2015.06.049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990, KAKENHI-PROJECT-26293175
[Journal Article] Hepatic progenitor cells of biliary origin with liver repopulation capacity2015
- Author(s)
  Lu WY, Bird T, Boulter L, Tsuchiya A, Cole A, Hay T, Guest R, Wojtacha D, Man TY, Mackinnon A, Ridgway R, Kendall T, Williams, Jamieson T, Raven A, Hay D, Iredale J, Clarke A, Sansom O, Forbes SJ
- Journal Title
  
  Nature Cell Biology
  
  Volume: 17(8) Issue: 8 Pages: 971-983
- DOI
  10.1038/ncb3203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990
[Journal Article] Factors predicting aggressiveness of non-hypervascular hepatic nodules detected on hepatobiliary phase of gadolinium ethoxybenzyl diethylene-triamine-pentaacetic-acid magnetic resonance imaging2015
- Author(s)
  Kanefuji T, Takano T, Suda T, Akazawa K, Yokoo T, Kamimura H, Kamimura K, Tsuchiya A, Takamura M, Kawai H, Yamagiwa S, Aoyama H, Nomoto M, Terai S
- Journal Title
  
  World J Gastroenterol
  
  Volume: 21(15) Issue: 15 Pages: 4583-4591
- DOI
  10.3748/wjg.v21.i15.4583
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990, KAKENHI-PROJECT-26860497
[Journal Article] Reduced NKG2D ligand expression in hepatocellular carcinoma correlates with early recurrence2012
- Author(s)
  Kamimura H, Yamagiwa S, Tsuchiya A, Takamura M, Matsuda Y, Ohkoshi S, Inoue M, Wakai T, Shirai Y, Nomoto M, Aoyagi Y.
- Journal Title
  
  J. Hepatol
  
  Volume: 56(2) Pages: 381-8
- Data Source
  KAKENHI-PROJECT-22790634
[Journal Article] Hepatocellular carcinoma with progenitor cell features distinguishable by the hepatic stem/progenitor cell marker NCAM2011
- Author(s)
  Tsuchiya A
- Journal Title
  
  Cancer Lett.
  
  Volume: 309 Issue: 1 Pages: 95-103
- DOI
  10.1016/j.canlet.2011.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390205, KAKENHI-PROJECT-22790634, KAKENHI-PROJECT-23659395
[Journal Article] Hepatocellular carcinoma with progenitor cell features distinguishable by the hepatic stem/progenitor cell marker NCAM2011
- Author(s)
  Tsuchiya A, Kamimura H, Tamura Y, Takamura M, Yamagiwa S, Suda T, Nomoto M, Aoyagi Y.
- Journal Title
  
  Cancer Lett
  
  Volume: 309(1) Pages: 95-103
- Data Source
  KAKENHI-PROJECT-22790634
[Journal Article] Clinicopathological analysis of CD133+ and NCAM+ human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas2009
- Author(s)
  Tsuchiya A, Kamimura H, Takamura M, Yamagiwa S, Matsuda Y, Sato Y, Nomoto M, Ichida T, Aoyagi Y
- Journal Title
  
  Hepatology Research 39
  
  Pages: 1080-1090
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] Successful Treatment in a Case of Massive Hepatocellular Carcinoma with Paraneoplastic Syndrome2009
- Author(s)
  Atsunori Tsuchiya
- Journal Title
  
  Case reports in gastroenterology 3
  
  Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] Clinicopathological analysis of CD133+ and NCAM+ human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas2009
- Author(s)
  Atsunori Tsuchiya
- Journal Title
  
  Hepatology Research 39
  
  Pages: 1080-1090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] Successful Treatment in a Case of Massive Hepatocellular Carcinoma with Paraneoplastic Syndrome2009
- Author(s)
  Tsuchiya A, Kubota T, Takizawa K, Yamada K, Wakai T, Matsuda Y, Honma T, Watanabe M, Shirai Y, Maruyama H, Nomoto M, Aoyagi Y
- Journal Title
  
  Case reports in gastroenterology 3
  
  Pages: 105-110
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] Successful treatment of multiple lung metastases of hepatocellular carcinoma by combined chemotherapy with docetaxel, cisplatin and tegafur/uracil2009
- Author(s)
  Atsunori Tsuchiya
- Journal Title
  
  World J Gastroenterol 15(14)
  
  Pages: 1779-1781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] Successful treatment of multiple lung metastases of hepatocellular carcinoma by combined chemotherapy with docetaxel, cisplatin and tegafur/uracil2009
- Author(s)
  Tsuchiya A, Imai M, Kamimura H, Togashi T, Watanabe K, Seki K, Ishikawa T, Ohta H, Yoshida T, Kamimura T
- Journal Title
  
  World J Gastroenterol 15(14)
  
  Pages: 1779-1781
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] 劇症肝炎に対する再生医学の現実性-内科医の立場で-2009
- Author(s)
  土屋淳紀
- Journal Title
  
  肝胆膵 59(3)
  
  Pages: 469-476
- Data Source
  KAKENHI-PROJECT-20790488
[Journal Article] Increased susceptibility to severe chronic liver damage in CXCR4 conditional knock-out mice
- Author(s)
  Tsuchiya A, Imai M, Kamimura H, Takamura M, Yamagiwa S, Sugiyama T, Nomoto M, Heike T, Nagasawa T, Nakahata T, Aoyagi Y
- Journal Title
  
  Dig Dis Sci
  
  Volume: (in print)
- Data Source
  KAKENHI-PROJECT-22790634
[Presentation] New normalへの提言-肝硬変に対する線維化改善を目指したトランスレーショナルリサーチ2023
- Author(s)
  土屋淳紀、渡邉雄介、寺井崇二
- Organizer
  JDDW
- Data Source
  KAKENHI-PROJECT-22K19933
[Presentation] New normalへの提言-肝硬変に対する線維化改善を目指したトランスレーショナルリサーチ2023
- Author(s)
  土屋淳紀、渡邉雄介、寺井崇二
- Organizer
  JDDW
- Data Source
  KAKENHI-PROJECT-23K24128
[Presentation] 肝硬変に対する細胞治療、細胞外小胞（エクソソーム）治療、ペプチド治療の開発状況2023
- Author(s)
  土屋淳紀、寺井崇二
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-22K19933
[Presentation] 肝硬変に対してのデザイナー細胞外小胞（エクソソーム）治療の可能性2023
- Author(s)
  土屋淳紀、寺井崇二
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-22K19933
[Presentation] 間葉系幹細胞由来細胞外小胞を用いた肝硬変治療法の開発（基礎研究から臨床応用へ）2022
- Author(s)
  寺井崇二、土屋淳紀
- Organizer
  日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-22K19933
[Presentation] 大腸菌の外膜小胞は肝硬変での炎症・線維化増悪に寄与する2022
- Author(s)
  夏井一輝、土屋淳紀、寺井崇二
- Organizer
  日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-23K24128
[Presentation] 肝硬変のマクロファージをターゲットとしたエクソソーム治療の可能性2022
- Author(s)
  土屋淳紀、寺井崇二
- Organizer
  消化器免疫学会
- Data Source
  KAKENHI-PROJECT-22K19933
[Presentation] Therapies using mesenchymal stem cells and their small extracellular vesicle for liver cirrhosis2022
- Author(s)
  Atsunori Tsuchiya, Shuji Terai
- Organizer
  JDDW
- Data Source
  KAKENHI-PROJECT-22K19933
[Presentation] エクソソームタンパクEps8の膵癌バイオマーカーとしての検討2022
- Author(s)
  林和直　土屋淳紀　寺井崇二
- Organizer
  第108回消化器病学会総会
- Data Source
  KAKENHI-PROJECT-21K07910
[Presentation] 大腸菌の外膜小胞は肝硬変での更なる炎症・線維化増悪に寄与する2022
- Author(s)
  夏井一輝、土屋淳紀、寺井崇二
- Organizer
  JDDW
- Data Source
  KAKENHI-PROJECT-23K24128
[Presentation] 肝硬変に対する他家間葉系幹細胞を用いた治験の進展2021
- Author(s)
  寺井崇二、土屋淳紀
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] HMGB1の部分ペプチドを用いた慢性肝疾患に対するセルフリー治療の開発2021
- Author(s)
  土屋淳紀、野尻俊介、寺井崇二
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 肝硬変に対するExosome治療2021
- Author(s)
  寺井崇二,土屋淳紀
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] 肝硬変に対するExosome治療2021
- Author(s)
  寺井崇二,土屋淳紀
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 肝硬変に対するエクソソーム治療の開発への課題2021
- Author(s)
  寺井崇二、土屋淳紀
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 間葉系幹細胞の治療効果メカニズム検証に基づく肝硬変に対するより効果的な治療法開発2020
- Author(s)
  土屋淳紀、高村昌昭、寺井崇二
- Organizer
  JDDW
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] 間葉系幹細胞のエクソソームによる肝線維化改善抗炎症性マクロファージ誘導法の開発2020
- Author(s)
  竹内卓、土屋淳紀、寺井崇二
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] 肝硬変に対する間葉系幹細胞由来エクソソーム療法の開発に向けて2020
- Author(s)
  土屋淳紀、竹内卓、寺井崇二
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] IFN-γ刺激下間葉系幹細胞由来エクソソームの肝線維化改善における効果・メカニズムの検証2020
- Author(s)
  土屋淳紀, 竹内卓, 寺井崇二
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 肝硬変に対する間葉系幹細胞由来エクソソーム療法の開発に向けて2020
- Author(s)
  土屋淳紀、竹内卓、寺井崇二
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 間葉系幹細胞のエクソソームによる肝線維化改善抗炎症性マクロファージ誘導法の開発2020
- Author(s)
  竹内卓、土屋淳紀、寺井崇二
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 非アルコール性脂肪性肝炎（NASH）モデルマウスを用いたスフィンゴシン1リン酸受容体ブロックによる脂質構成の変化と発癌機構の解明2020
- Author(s)
  吉田智彰、土屋淳紀、寺井崇二
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] IFN-γ刺激下間葉系幹細胞由来エクソソームの肝線維化改善における効果・メカニズムの検証2020
- Author(s)
  土屋淳紀, 竹内卓, 寺井崇二
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] 間葉系幹細胞の治療効果メカニズム検証に基づく肝硬変に対するより効果的な治療法開発2020
- Author(s)
  土屋淳紀、高村昌昭、寺井崇二
- Organizer
  JDDW
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 新たなNASHモデルマウス開発及び間葉系幹細胞による治療効果の検証2019
- Author(s)
  渡邉貴之、土屋淳紀、寺井崇二
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 間葉系幹細胞を用いた消化器疾患の再生医療の治療戦略2019
- Author(s)
  土屋淳紀、高村昌昭、寺井崇二
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] IFN-γ;刺激下採取間葉系幹細胞由来エクソソームは抗炎症マクロファージを誘導し貧食能を更新させ、肝線維化改善に寄与する2019
- Author(s)
  土屋淳紀、竹内　卓、野尻俊介、小川雅裕、寺井崇二
- Organizer
  日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 肝硬変に対する間葉系幹細胞由来のエクソソーム療法の開発に向けて2019
- Author(s)
  土屋淳紀、竹内卓、寺井崇二
- Organizer
  日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] 消化器疾患での間葉系幹細胞を用いた再生医療の治療戦略2019
- Author(s)
  土屋淳紀、小川雅裕、野尻俊介、渡邉貴之、竹内卓、小島雄一、川田雄三、寺井崇二
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] EXOSOMES ISOLATED FROM HUMAN ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS ATTENUATE INFLAMMATION AND FIBROSIS IN A CIRRHOSIS MOUSE MODEL2019
- Author(s)
  Atsunori Tsuchiya、Suguru Takeuchi、Takayuki Watanabe、Shunsuje Nojiri、Masahiro Ogawa、Shuji Terai
- Organizer
  AASLD, Liver Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 新たなNASHモデルマウスの開発と間葉系幹細胞およびエクソソームによる治療効果の検証2019
- Author(s)
  土屋淳紀渡邉貴之小川雅裕野尻俊介竹内　卓寺井崇二
- Organizer
  肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 消化器疾患での間葉系幹細胞を用いた治療法開発2019
- Author(s)
  土屋淳紀、高村昌昭、寺井崇二
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] EXOSOMES ISOLATED FROM HUMAN ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS ATTENUATE INFLAMMATION AND FIBROSIS IN A CIRRHOSIS MOUSE MODEL2019
- Author(s)
  Atsunori Tsuchiya、Suguru Takeuchi、Takayuki Watanabe、Shunsuke Nojiri、Masahiro Ogawa、Shuji Terai
- Organizer
  Cold Spring Harbor Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 消化器疾患での間葉系幹細胞を用いた治療法開発2019
- Author(s)
  土屋淳紀、高村昌昭、寺井崇二
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-19H03636
[Presentation] 間葉系幹細胞を指揮細胞として用いた肝硬変に対する再生医療の治療戦略2019
- Author(s)
  寺井崇二、土屋淳紀、竹内卓
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-18K07903
[Presentation] 肝前駆細胞マーカー陽性肝細胞癌の臨床的特徴とAFP-L3分画を用いた拾い上げの可能性2017
- Author(s)
  清野智、土屋淳紀、小島雄一、渡邉雄介、阿部聡司、坂牧僚、上村顕也、高村昌昭、川合弘一、山際訓、寺井崇二
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] 骨髄由来間葉系幹細胞と培養マクロファージの混合投与療法による肝硬変治療2017
- Author(s)
  渡邉雄介、土屋淳紀、寺井崇二
- Organizer
  日本再生医療学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] 肝硬変に対する自己由来細胞を用いた再生療法から他家細胞を用いた再生医療へ2017
- Author(s)
  寺井崇二、土屋淳紀
- Organizer
  日本再生医療学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] Combination therapy with mesenchymal stem cells and macrophages from bone marrow shows favorable outcome in mouse CCl4-induced liver cirrhosis model2016
- Author(s)
  渡邉雄介、土屋淳紀
- Organizer
  AASLD 2016
- Place of Presentation
  ボストン（アメリカ合衆国）
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] Comparative effectiveness of mesenchymal stem cell therapy and macrophage cell therapy in a liver cirrhosis disease model2016
- Author(s)
  土屋淳紀
- Organizer
  APDW 2016
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] 肝線維化改善、再生促進に向け、骨髄からの選択的な間葉系幹細胞とマクロファージ培養の開発2016
- Author(s)
  渡邉雄介、土屋淳紀、清野智、川田雄三、川合弘一、山際訓、寺井崇二
- Organizer
  第１５回日本再生医療学会
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] 肝硬変の治療メカニズム解析のための骨髄由来のMSC、マクロファージ培養および解析2016
- Author(s)
  土屋淳紀
- Organizer
  第３７回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都府京都市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] 肝幹前駆細胞マーカー陽性肝細胞癌の臨床的意義や腫瘍マーカーとの2016
- Author(s)
  土屋淳紀、小島雄一、清野智、渡邉雄介、川田雄三、
- Organizer
  第15会再生医療学会
- Place of Presentation
  大阪国際会議場(大阪府、大阪市）
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] Significance of hepatic progenitor cell marker-positive hepatocellular carcinoma and its possible prediction by AFP-L32016
- Author(s)
  土屋淳紀
- Organizer
  AASLD 2016
- Place of Presentation
  Boston (USA)
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] Significance of hepatic progenitor cell marker-positive hepatocellular carcinoma and its possible prediction by AFP-L32016
- Author(s)
  土屋淳紀
- Organizer
  AASLD 2016
- Place of Presentation
  ボストン（アメリカ合衆国）
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] AFP-L3分画陰性化後の再上昇から肝細胞癌の再発を早期に予知し得た２例2016
- Author(s)
  薛徹、土屋淳紀
- Organizer
  肝臓学会東部会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] Combination therapy with mesenchymal stem cells and macrophages from bone marrow shows favorable outcome in mouse CCl4-induced liver cirrhosis model2016
- Author(s)
  渡邉雄介、土屋淳紀、寺井崇二
- Organizer
  AASLD 2016
- Place of Presentation
  Boston (USA)
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] Comparative effectiveness of mesenchymal stem cell therapy and macrophage cell therapy in a liver cirrhosis disease model2016
- Author(s)
  土屋淳紀
- Organizer
  APDW 2016
- Place of Presentation
  Kobe Convention Center (兵庫県神戸市）
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] 肝硬変の治療メカニズム解析のための骨髄由来のMSC,マクロファージ培養および解析2016
- Author(s)
  土屋淳紀
- Organizer
  日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都府京都市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] 間葉系幹細胞、マクロファージの相互作用による新しい肝硬変治療を目指して2016
- Author(s)
  土屋淳紀
- Organizer
  日本肝臓学会東部会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-26293175
[Presentation] 肝幹前駆細胞nicheで再生されるstromal cell derived factor-1(SDF-1)は肝再生促進に関わる2015
- Author(s)
  清野　智土屋　淳紀，寺井　崇二
- Organizer
  JDDW日本消化器関連学会週間
- Place of Presentation
  東京品川プリンスホテル（東京都、港区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] Analysis of prognostic significance of hepatic progenitor cell marker-positive hepatocellular carcinoma2015
- Author(s)
  Tsuchiya A Nomoto M, Terai S
- Organizer
  JDDW日本消化器関連学会週間（２０１５）
- Place of Presentation
  東京品川プリンスホテル（東京都、港区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K08990
[Presentation] 肝幹前駆細胞マーカーNCAMを用いたHCC with progenitor cell featuresの血清診断および治療への応用の可能性2010
- Author(s)
  土屋淳紀
- Organizer
  JDDW 2010
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22790634
[Presentation] 肝幹前駆細胞マーカーNCAMを用いたHCC with progenitor cell featuresの血清診断及び治療への応用の可能性2010
- Author(s)
  土屋淳紀、野本実、青柳豊
- Organizer
  JDDW2010
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22790634
[Presentation] 人障害肝内に出現する肝幹前駆細胞の分化階層性の解析および肝癌幹細胞マーカーとしての可能性2009
- Author(s)
  土屋淳紀
- Organizer
  第106回内科学会総会
- Place of Presentation
  東京都
- Year and Date
  2009-04-12
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] 急性、慢性、人障害肝に見られるNCAM陽性肝幹前駆細胞およびNCAM陽性肝細胞癌の解析2009
- Author(s)
  土屋淳紀
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形市
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] 術前CDDP肝動注療法にて、肝機能を保ちかつ著効し狭心症加療後切除し長期生存した多血症、高脂血症の腫瘍随伴症候群を伴う高齢者巨大肝細胞癌の一例2008
- Author(s)
  土屋淳紀
- Organizer
  第37回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] Sca-1+ endothelial cells reside in the portal area of the liver and contribute to rapid recovery from acute liver disease2008
- Author(s)
  土屋淳紀
- Organizer
  6^<th> ISSCR (International Society for Stem Cell Research)
- Place of Presentation
  フィラデルフィア(アメリカ)
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] 門脈域に存在するSca-1陽性血管内皮細胞は急性肝障害時の早期回復に貢献する2008
- Author(s)
  土屋淳紀
- Organizer
  JDDW2008(日本消化器関連学会集会)
- Place of Presentation
  東京
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] 急性、慢性障害肝組織中でのCD133, NCAM陽性細胞の出現とその分化階層性の解析2008
- Author(s)
  土屋淳紀
- Organizer
  第40回臨床分子形態学会
- Place of Presentation
  福岡
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] 人障害肝内に出現する肝幹前駆細胞の分化階層性の解析および肝癌幹細胞マーカーとしての可能性
- Author(s)
  土屋淳紀、高村昌昭、山際訓、野本実、青柳豊
- Organizer
  内科学会総会
- Data Source
  KAKENHI-PROJECT-20790488
[Presentation] 急性、慢性、人障害肝に見られるNCAM陽性肝幹前駆細胞およびNCAM陽性肝細胞癌の解析
- Author(s)
  土屋淳紀、野本実、青柳豊
- Organizer
  肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20790488

1. TERAI Shuji (00332809)

# of Collaborated Projects: 13 results

# of Collaborated Products: 64 results
2. 上村顕也 (00579146)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
3. Satoru Hashimoto (10768667)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. Kamimura Hiroteru (40706420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. 山際訓 (10419327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 佐藤祐一 (00401761)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 川合弘一 (80419291)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 佐藤裕樹 (50644556)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 高村昌昭 (20422602)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. 横尾健 (80750629)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TABATA Yasuhiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. Yagi Kazuyoshi (20220121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 藤澤浩一 (00448284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 石川剛 (20569305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高見太郎 (60511251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 坂井田功 (80263763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岩本拓也 (80634716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山本直樹 (90448283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 坂牧僚 (40792289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 薛徹 (40837184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 林和直 (70743897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 佐野将之 (80415687)

# of Collaborated Projects: 1 results

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23. 西村健 (80500610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 植田幸嗣 (10509110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 岡真優子 (40347498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 渡邉雄介 (00883844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 阿部寛幸 (50880168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 木村成宏 (80838649)

# of Collaborated Projects: 1 results

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29. 酒井規裕 (00911984)

# of Collaborated Projects: 1 results

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30. 柏村健 (70419290)

# of Collaborated Projects: 1 results

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31. KOJIMA Yuichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
32. SEINO Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
33. NISHINA Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. TOGUCHIDA Junya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. ITOH Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 藤木克則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 野中尋史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 凌一葦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 新保敬史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 玉井克人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

tsuchiya atsunori 土屋 淳紀

Tsuchiya Atsunori 土屋 淳紀

TSUCHIYA Ataunori 土屋 淳紀

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Development of liver regeneration therapy using super exosomes with multiple and high volume protein delivery systemsPrincipal Investigator

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Elucidation of the Mechanism of Regenerative Insufficiency in Advanced Liver Cirrhosis Caused by Intestinal Bacterial Extracellular Vesicles and Development of Prevention and Treatment MethodsPrincipal Investigator

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Development of novel anti-inflammatory therapy using mesenchymal stem cellsPrincipal Investigator

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Analysis of the factors of malignant behavior in hepatic progenitor cell marker expressing hepatocellular carcinomaPrincipal Investigator

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tsuchiya atsunori 土屋淳紀

Tsuchiya Atsunori 土屋淳紀

TSUCHIYA Ataunori 土屋淳紀

[Book] 【慢性肝臓病の克服を目指して】肝臓リハビリテーションと再生医療の開発状況日本内科学会雑誌2024