ENDO HIROKI 遠藤宏樹

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ENDO Hiroki 遠藤宏樹

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Researcher Number	70468164
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2016: 横浜市立大学, 附属病院, 助教 2011 – 2012: 横浜市立大学, 附属病院, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Pathological medical chemistry
Keywords	Principal Investigator 大腸発癌 / 大腸発がん / 脂肪酸 / レプチン

アスピリン小腸潰瘍モデルマウスの確立および分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  遠藤宏樹
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Investigation of the mechanism underlying the effect of fatty acid on colorectal carcinogenesisPrincipal Investigator
- Principal Investigator
  
  ENDO HIROKI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Investigation of the mechanism underlying the effect of leptin on colorectal carcinogenesisPrincipal Investigator
- Principal Investigator
  
  ENDO Hiroki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yokohama City University

All 2015 2014 2012 2011 Other

All Journal Article Presentation

[Journal Article] Association between factors associated with colorectal cancer and rectal aberrant crypt foci in humans.2015
- Author(s)
  Akiko Ezuka, Eiji Sakai, Kenichi Kawana, Hajime Nagase, Yukio Kakuta, Shiori Uchiyama, Hidenori Ohkubo, Takuma Higurashi, Takashi Nonaka, Hiroki Endo, Hirokazu Takahashi, Atsushi Nakajima.
- Journal Title
  
  Oncol Lett.
  
  Volume: １０ Issue: 6 Pages: 3689-95
- DOI
  10.3892/ol.2015.3763
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860517
[Journal Article] Visual distraction alone for the improvement of colonoscopy-related pain and satisfaction.2015
- Author(s)
  Shotaro Umezawa, Takuma Higurashi, Shiori Uchiyama, Eiji Sakai, Hidenori Ohkubo, Hiroki Endo, Takashi Nonaka, Atsushi Nakajima.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 21 Issue: 15 Pages: 4707-14
- DOI
  10.3748/wjg.v21.i15.4707
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860517
[Journal Article] 肥満関連疾患をターゲットとしたメトホルミンによる大腸腫瘍の科学予防の可能性2014
- Author(s)
  23.日暮琢磨、酒井英嗣、内山詩織、梅沢翔太郎、遠藤宏樹、高橋宏和、中島淳
- Journal Title
  
  消化器内科
  
  Volume: 58 Pages: 612-616
- Data Source
  KAKENHI-PROJECT-26860517
[Journal Article] 肥満・生活習慣病と大腸癌2014
- Author(s)
  遠藤宏樹、日暮琢磨、高橋宏和、中島　淳
- Journal Title
  
  日本消化器内視鏡学会雑誌
  
  Volume: 55 Pages: 3735-3744
- NAID
  130003386602
- Data Source
  KAKENHI-PROJECT-26860517
[Journal Article] Methylation epigenotypes and genetic features in colorectal laterally spreading tumors2014
- Author(s)
  Sakai E, Ohata K, Chiba H, Matsuhashi N, Doi N, Fukushima J, Endo H, Takahashi H, Tsuji S, Yagi K, Matsusaka K, Aburatani H, Nakajima A, Kaneda A.
- Journal Title
  
  Int J Cancer
  
  Volume: in press Issue: 7 Pages: 1586-95
- DOI
  10.1002/ijc.28814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790713, KAKENHI-PROJECT-26670595, KAKENHI-PROJECT-26860257, KAKENHI-PROJECT-26860517
[Journal Article] Relationship of human rectal aberrant crypt foci and formation of colorectal polyp: One-year following up after polypectomy.2012
- Author(s)
  Hirokazu Takahashi
- Journal Title
  
  World J Gastrointest Endosc
  
  Volume: 4 Issue: 12 Pages: 561-4
- DOI
  10.4253/wjge.v4.i12.561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Identification of preneoplastic lesions as mucin-depleted foci in patients with sporadic colorectal cancer2012
- Author(s)
  Sakai E, Morioka T, Yamada E, Ohkubo H, Higurashi T, Hosono K, Endo H, Takahashi H, Takamatsu R, Cui C, Shiozawa M, Akaike M, Samura H, Nishimaki T, Nakajima A, Yoshimi N
- Journal Title
  
  Cancer Sci
  
  Volume: 103(1) Pages: 144-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374
[Journal Article] Increased tumor necrosis factor receptor 1 expression in human colorectal adenomas.2012
- Author(s)
  Kunihiro Hosono
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 18 Issue: 38 Pages: 5360-8
- DOI
  10.3748/wjg.v18.i38.5360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant crypt foci (ACF): a double-blind randomized controlled trial.2012
- Author(s)
  Takuma Higurashi
- Journal Title
  
  BMC Cancer
  
  Volume: 12 Issue: 1 Pages: 413-413
- DOI
  10.1186/1471-2407-12-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Number of aberrant crypt foci in the rectum is a useful surrogate marker of colorectal adenoma recurrence.2012
- Author(s)
  Takashi Uchiyama
- Journal Title
  
  Dig Endosc
  
  Volume: 24 Issue: 5 Pages: 353-7
- DOI
  10.1111/j.1443-1661.2012.01289.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948
[Journal Article] Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial.2012
- Author(s)
  Higurashi T, Takahashi H, Endo H, Hosono K, Uchiyama T, Hata Y,Ezuka A, Yamanaka S, Inayama Y,et.al.
- Journal Title
  
  BMC Cancer.
  
  Volume: 12(1) Issue: 1 Pages: 118-118
- DOI
  10.1186/1471-2407-12-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590468, KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Role of the long form leptin receptor and of the STAT3 signaling pathway in colorectal cancer progression2011
- Author(s)
  Uchiyama T, Takahashi H, Endo H, Sugiyama M, Sakai E, Hosono K, Nagashima Y, Inayama Y, Wada K, Hippo Y, Nakajima A
- Journal Title
  
  Int J Oncol
  
  Volume: 39(4) Pages: 935-40
- DOI
  10.3892/ijo.2011.1105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374
[Journal Article] Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis2011
- Author(s)
  Endo H, Hosono K, Uchiyama T, Sakai E, Sugiyama M, Takahashi H, Nakajima N, Wada K, Takeda K, Nakagama H, Nakajima A
- Journal Title
  
  Gut
  
  Volume: 60(10) Issue: 10 Pages: 1363-71
- DOI
  10.1136/gut.2010.235754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374
[Journal Article] Role of the long form leptin receptor and of the STAT3 signaling pathway in colorectal cancer progression.2011
- Author(s)
  Uchiyama T, Takahashi H, Endo H, Sugiyama M, Sakai E, Hosono K, Nagashima Y, Inayama Y, Wada K, Hippo Y, Nakajima A.
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 935-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374
[Journal Article] Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis.2011
- Author(s)
  Endo H, Hosono K, Uchiyama T, Sakai E, Sugiyama M, Takahashi H, Nakajima N, Wada K, Takeda K, Nakagama H, Nakajima A.
- Journal Title
  
  Gut
  
  Volume: 60 Pages: 1363-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374
[Journal Article] 食事摂取により増大する大腸癌：レプチンシグナルの関与.2011
- Author(s)
  遠藤宏樹、細野邦広、酒井英嗣、内山崇、日暮琢磨、高橋宏和、中島淳.
- Journal Title
  
  消化器内科
  
  Volume: 52 Pages: 582-590
- Data Source
  KAKENHI-PROJECT-23790374
[Journal Article] 【消化器癌をめぐる栄養療法】食事摂取により増大する大腸癌:レプチンシグナルの関与2011
- Author(s)
  遠藤宏樹、細野邦広、酒井英嗣、内山崇、日暮琢磨、高橋宏和、中島淳
- Journal Title
  
  消化器内科(1844-2895)
  
  Volume: 52巻6号 Pages: 582-590
- URL
  http://ci.nii.ac.jp/naid/40018927290
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] Metformin efficacy and safety for colorectal polyps: A double-blind randomized controlles trial.2015
- Author(s)
  Takuma Higurashi, Kunihiro Hosono, Shotaro Umezawa, Shiori Uchiyama, Takashi Uchiyama, Hiroki Endo, Atsushi Nakajima.
- Organizer
  United European Gastroenterology Week
- Place of Presentation
  Vienna, Austria
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860517
[Presentation] 大腸上皮における飽和脂肪酸の影響．2015
- Author(s)
  内山詩織、日暮琢磨、梅沢翔太郎、遠藤宏樹、中島淳
- Organizer
  第23回日本消化器関連学会週間（JDDW 2015）
- Place of Presentation
  グランドプリンスホテル高輪（東京都港区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860517
[Presentation] 当院における大腸カプセル内視鏡施行例の検討．2015
- Author(s)
  梅沢翔太郎、遠藤宏樹、鹿野島健二、稲生優海、松浦瑞恵、冬木晶子、内山詩織、酒井英嗣、大久保秀則、日暮琢磨、飯田洋、野中敬、中島淳
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26860517
[Presentation] GPR120 経路をターゲットとしたエイコサペントエン酸（EPA）による大腸腫瘍化学予防2014
- Author(s)
  72梅沢翔太郎, 日暮琢磨, 内山詩織, 酒井英嗣, 遠藤宏樹, 中島淳
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市立大学（神奈川県）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26860517
[Presentation] AMPK-mTOR 経路をターゲットとしたメトホルミンによる大腸腫瘍化学予防2014
- Author(s)
  73日暮琢磨, 梅沢翔太郎, 内山詩織, 酒井英嗣, 細野邦弘, 遠藤宏樹, 中島淳
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市立大学（神奈川県）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26860517
[Presentation] レスベラトロールによる大腸発癌予防効果に関する検討2012
- Author(s)
  酒井英嗣, 遠藤宏樹, 中島淳
- Organizer
  第98回日本消化器病学会総会ミニシンポジウム 2 (Nutraceutical をめぐって)
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 低用量 resveratrol は大腸腫瘍の initiationに影響を与えないが, STAT3 経路を介して大腸腫瘍の progression を抑制する2012
- Author(s)
  酒井英嗣, 遠藤宏樹, 中島淳, 山田英司, 日暮琢磨, 大久保秀則, 高橋宏和
- Organizer
  第71回日本癌学会学術総会口演 (化学物質とがん予防)
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 大腸腫瘍を増大させるレプチンシグナル: Cre/flox動物モデルを用いた検討2012
- Author(s)
  日暮琢磨, 遠藤宏樹, 酒井英嗣, 大久保秀則, 山田英司, 高橋宏和, 中島淳
- Organizer
  第71回日本癌学会学術総会ポスターセッション (化学物質とがん予防)
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] The histopathological characteristics of mucin-depleted foci in patients with sporadic colorectal cancer2012
- Author(s)
  akai E, Takahashi H, Yamada E, Higurashi T, Ohkubo H, Hosono K, Endo H, Kato S, Nakajima A, Cui C, Takamatsu R, Yoshimi N
- Organizer
  AACR 2012 (pathogenesis of gastrointestinal and hepatocellular carcinomas)
- Place of Presentation
  Chicago, U.S.A
- Year and Date
  2012-04-02
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 肥満と大腸癌: メカニズムと予防2011
- Author(s)
  中島淳、遠藤宏樹、酒井英嗣、高橋宏和
- Organizer
  第28回日本医学会総会2011東京,シンポジウム6 (からだの調節と代謝, 肥満の成因と治療)
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2011-04-08
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 大腸発癌におけるIL-6の作用解析2011
- Author(s)
  内山崇、高橋宏和、酒井英嗣、杉山美智子、細野邦広、遠藤宏樹、中島淳
- Organizer
  第7回日本消化管学会総会学術集会ワークショップ16 (肥満, 代謝異常と消化管疾患:病態解明への新たなアプローチ)
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-02-02
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] Validity of ACF using as a surrogate biomarker for colorectal cancer2011
- Author(s)
  Sakai E, Takahashi H, Kato S, Uchiyama T, Hosono K, Endo H, Maeda S, Yoneda M, Taguri M, Nakajima A
- Organizer
  AACR conference on frontiers in cancer prevention research, poster session
- Place of Presentation
  Boston, U.S.A.
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 新規大腸化学発癌予防薬としてのResveratrolの可能性2011
- Author(s)
  酒井英嗣、遠藤宏樹、中島淳
- Organizer
  第7回日本消化管学会総会学術集会ワークショップ7 (大腸癌の治療, 予防に向けた新規標的分子の探索)
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-02-02
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 肥満と大腸癌: 大腸腫瘍を増大させるレプチンシグナル2011
- Author(s)
  遠藤宏樹、内山崇、酒井英嗣、細野邦広、高橋宏和、中島淳
- Organizer
  第7回日本消化管学会総会学術集会ワークショップ16 (肥満, 代謝異常と消化管疾患: 病態解明への新たなアプローチ)
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-02-02
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 低用量resveratrolは大腸腫瘍のinitiationに影響を与えないが, STAT3経路を介して大腸腫瘍のprogressionを抑制する.
- Author(s)
  酒井英嗣、遠藤宏樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] 大腸腫瘍を増大させるレプチンシグナル: 動物モデルを用いた検討.
- Author(s)
  日暮琢磨、遠藤宏樹
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] レスベラトロールによる大腸発癌予防効果に関する検討.
- Author(s)
  酒井英嗣、遠藤宏樹
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] EICOSAPENTAENOIC ACID (EPA) SUP-PRESSES COLORECTAL ABERRANT CRYPT FOCI (ACF) AND CELL PROLIFERATION IN COLORECTAL EPITHELIUM VIA GPR120
- Author(s)
  84Higurashi T , Uchiyama S , Umezawa S , Sakai E , Ohkubo H , Endo H , Takahashi H , Nakajima A
- Organizer
  22nd United European Gastroenterology Week
- Place of Presentation
  Vienna（オーストリア）
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-26860517
[Presentation] 大腸腫瘍を増大させるレプチンシグナル: Cre/flox動物モデルを用いた検討.
- Author(s)
  日暮琢磨、遠藤宏樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790374
[Presentation] The histopathological characteristics of mucin-depleted foci in patients with sporadic colorectal cancer.
- Author(s)
  Eiji Sakai、Hiroki Endo
- Organizer
  AACR Annual Meeting 2012:
- Place of Presentation
  U.S.A., Chicago
- Data Source
  KAKENHI-PROJECT-23790374

1. 中島淳 (30326037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 山中正二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ENDO HIROKI 遠藤 宏樹

ENDO Hiroki 遠藤 宏樹

Research Projects

Research Products

Co-Researchers

アスピリン小腸潰瘍モデルマウスの確立および分子メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanism underlying the effect of fatty acid on colorectal carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanism underlying the effect of leptin on colorectal carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association between factors associated with colorectal cancer and rectal aberrant crypt foci in humans.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Visual distraction alone for the improvement of colonoscopy-related pain and satisfaction.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肥満関連疾患をターゲットとしたメトホルミンによる大腸腫瘍の科学予防の可能性2014

Author(s)

Journal Title

Data Source

[Journal Article] 肥満・生活習慣病と大腸癌2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Methylation epigenotypes and genetic features in colorectal laterally spreading tumors2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relationship of human rectal aberrant crypt foci and formation of colorectal polyp: One-year following up after polypectomy.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of preneoplastic lesions as mucin-depleted foci in patients with sporadic colorectal cancer2012

Author(s)

Journal Title

Data Source

[Journal Article] Increased tumor necrosis factor receptor 1 expression in human colorectal adenomas.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant crypt foci (ACF): a double-blind randomized controlled trial.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Number of aberrant crypt foci in the rectum is a useful surrogate marker of colorectal adenoma recurrence.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the long form leptin receptor and of the STAT3 signaling pathway in colorectal cancer progression2011

Author(s)

Journal Title

DOI

ENDO HIROKI 遠藤宏樹

ENDO Hiroki 遠藤宏樹

[Journal Article] 【消化器癌をめぐる栄養療法】食事摂取により増大する大腸癌:レプチンシグナルの関与2011