Hayakawa Hideki 早川英規

Researcher Number	70468594
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院連合小児発達学研究科, 助教 2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, 特任研究員
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院連合小児発達学研究科, 助教 2023: 大阪大学, 大学院医学系研究科, 特任研究員 2022: 大阪大学, 大学院医学系研究科, 招へい教員 2016 – 2021: 大阪大学, 医学系研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology
Keywords	Principal Investigator αシヌクレイン / alpha-synuclein / パーキンソン病 / αsynuclein / 脳・神経 / 脳神経疾患 / オリゴデンドロサイト / 多系統萎縮症 / α-synuclein

パーキンソン病モデルを用いたαシヌクレインとミクログリアの相互作用の解明Principal Investigator
- Principal Investigator
  
  早川英規
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  The University of Osaka
Interactions between neuroinflammation and alpha-synuclein in a Parkinson's disease model.Principal Investigator
- Principal Investigator
  
  Hayakawa Hideki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Osaka University
Structurally distinct alpha-synuclein fibrils induce robust Parkinsonian pathologyPrincipal Investigator
- Principal Investigator
  
  Hayakawa Hideki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Osaka University

All 2024 2023 2022 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Structurally Distinct α‐Synuclein Fibrils Induce Robust Parkinsonian Pathology2019
- Author(s)
  Hayakawa Hideki、Nakatani Rie、Ikenaka Kensuke、Aguirre Cesar、Choong Chi‐Jing、Tsuda Hiroshi、Nagano Seiichi、Koike Masato、Ikeuchi Takeshi、Hasegawa Masato、Papa Stella M.、Nagai Yoshitaka、Mochizuki Hideki、Baba Kousuke
- Journal Title
  
  Movement Disorders
  
  Volume: 35 Issue: 2 Pages: 256-267
- DOI
  10.1002/mds.27887
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09299, KAKENHI-PROJECT-18H02718, KAKENHI-PROJECT-18H02741, KAKENHI-PROJECT-16K09690, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K19658, KAKENHI-PROJECT-16K19512, KAKENHI-PUBLICLY-17H05699, KAKENHI-PROJECT-16H05325
[Journal Article] In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson’s disease2018
- Author(s)
  Uenaka Takeshi、Satake Wataru、Cha Pei-Chieng、Hayakawa Hideki、Baba Kousuke、Jiang Shiying、Kobayashi Kazuhiro、Kanagawa Motoi、Okada Yukinori、Mochizuki Hideki、Toda Tatsushi
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 27 Pages: 3974-3985
- DOI
  10.1093/hmg/ddy279
- NAID
  120006549191
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19512, KAKENHI-PUBLICLY-17H05700, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-17H04056
[Journal Article] パーキンソン病の動物モデル2017
- Author(s)
  早川　英規
- Journal Title
  
  オベリスク
  
  Volume: 42 Pages: 24-32
- Data Source
  KAKENHI-PROJECT-16K19512
[Presentation] Neuroinflammation potentiates α-synuclein pathology in a mouse model of Parkinson's disease.2024
- Author(s)
  Hideki Hayakawa
- Organizer
  ADPD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07903
[Presentation] 神経炎症はパーキンソン病モデルマウスにおけるα-シヌクレインの病理学的作用を増強する。2023
- Author(s)
  早川　英規
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07903
[Presentation] 神経炎症がパーキンソン病モデルマウスのα-シヌクレイン病理を増強する。2022
- Author(s)
  早川英規
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-20K07903
[Presentation] In vitroにおけるalpha-synuclein細胞外分泌機構の検討2019
- Author(s)
  Hideki Hayakawa, Kousuke Baba, Chi-Jing Choong, Kensuke Ikenaka , Toshihide Takeuchi, Yoshitaka Nagai, Hideki Mochizuki
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-16K19512
[Presentation] I Intranigral inoculation of Parkinson's disease linked mutation G51D alpha-synuclein firbils induces Lewy-like pathology in mice2018
- Author(s)
  Hideki Hayakawa
- Organizer
  IAPRD2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19512
[Presentation] 野生型及び変異α synuclein 凝集体の分子特性に関する in vitro 及び in vivo での比較検討2018
- Author(s)
  早川　英規
- Organizer
  第12回パーキンソン病・運動機能コングレス
- Data Source
  KAKENHI-PROJECT-16K19512
[Presentation] In vitro assessment of extracelluler alpha-synuclein secration2017
- Author(s)
  Hideki Hayakawa
- Organizer
  World congress of neurology 2017
- Data Source
  KAKENHI-PROJECT-16K19512
[Presentation] 培養細胞系におけるαsynuclein伝播、凝集モデルの確立2016
- Author(s)
  早川英規
- Organizer
  第10回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都ホテルオークラ
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19512
[Presentation] Establishment of in vitro model to elucidate mechanism u nderlying propagation of alpha-synuclein2016
- Author(s)
  早川英規
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K19512

1. 馬場孝輔 (90750159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Hayakawa Hideki 早川 英規

Research Projects

Research Products

Co-Researchers

パーキンソン病モデルを用いたαシヌクレインとミクログリアの相互作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interactions between neuroinflammation and alpha-synuclein in a Parkinson's disease model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structurally distinct alpha-synuclein fibrils induce robust Parkinsonian pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structurally Distinct α‐Synuclein Fibrils Induce Robust Parkinsonian Pathology2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson’s disease2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] パーキンソン病の動物モデル2017

Author(s)

Journal Title

Data Source

[Presentation] Neuroinflammation potentiates α-synuclein pathology in a mouse model of Parkinson's disease.2024

Author(s)

Organizer

Data Source

[Presentation] 神経炎症はパーキンソン病モデルマウスにおけるα-シヌクレインの病理学的作用を増強する。2023

Author(s)

Organizer

Data Source

[Presentation] 神経炎症がパーキンソン病モデルマウスのα-シヌクレイン病理を増強する。2022

Author(s)

Organizer

Data Source

[Presentation] In vitroにおけるalpha-synuclein細胞外分泌機構の検討2019

Author(s)

Organizer

Data Source

[Presentation] I Intranigral inoculation of Parkinson's disease linked mutation G51D alpha-synuclein firbils induces Lewy-like pathology in mice2018

Author(s)

Organizer

Data Source

[Presentation] 野生型及び変異α synuclein 凝集体の分子特性に関する in vitro 及び in vivo での比較検討2018

Author(s)

Organizer

Data Source

[Presentation] In vitro assessment of extracelluler alpha-synuclein secration2017

Author(s)

Organizer

Data Source

[Presentation] 培養細胞系におけるαsynuclein伝播、凝集モデルの確立2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Establishment of in vitro model to elucidate mechanism u nderlying propagation of alpha-synuclein2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Hayakawa Hideki 早川英規