Sekiya Mizuki 關谷瑞樹

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SEKIYA Mizuki 關谷瑞樹

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Researcher Number	70509033
Other IDs
Affiliation (Current)	2025: 岩手医科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 岩手医科大学, 薬学部, 准教授 2016 – 2021: 岩手医科大学, 薬学部, 助教 2012 – 2013: 岩手医科大学, 薬学部, 助教 2009 – 2010: Iwate Medical University, 薬学部, 助教 2008: 岩手医科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Physical pharmacy Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 44010:Cell biology-related / Biological pharmacy / Functional biochemistry
Keywords	Principal Investigator F-ATPase / 歯周病 / 虫歯 / A-ATPase / ポリフェノール / ATP合成酵素 / S. mutans / S. anginosus / プロトンポンプ / う蝕 … More / プロトン輸送ATPase / 阻害剤 / 酵素 / イオン輸送 / 歯周病菌 / 虫歯菌 / P. gingivalis / P. gingivitis / ATP synthase / 生物物理 / 細菌 / 感染症 / 薬学 / プロトン輸送 ATPase / Curcumin / FoF1 / ATP 合成酵素 / V-ATPase / プロトンATPase … More Except Principal Investigator 破骨細胞 / 分泌リソソーム / オルガネラ輸送 / V-ATPase / 骨吸収 / Rab7 / プロトンポンプ / リソソーム / 神経伝達物質の分泌 / Rabタンパク質 / 液胞型ATPase / インスリン分泌 / 輸送 / オルガネラ / 分泌 / Ccz1 / Mon1 / GEF / Rab / 小胞輸送 / 液胞型プロトンポンプ / Rab27 / ATPase / 酸性環境 / マクロファージ / F型ATPase / V型ATPase / 阻害剤 / F-ATPase Less

嫌気性病原菌におけるアーキア型プロトン輸送ATPaseの作動機構と生理学的役割Principal Investigator
- Principal Investigator
  
  關谷瑞樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Iwate Medical University
Ion transport network in oral pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  Sekiya Mizuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Iwate Medical University
Mechanism underlying organelle trafficking regulated through structual diversity of proton pump V-ATPase
- Principal Investigator
  
  中西真弓
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Iwate Medical University
Common principle of secretory lysosome transport and universal mechanism of organelle trafficking
- Principal Investigator
  
  Goto-Matsumoto Naomi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Iwate Medical University
A novel approach to drug development targeting to proton pumping ATPasePrincipal Investigator
- Principal Investigator
  
  Sekiya Mizuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Iwate Medical University
Exploitation of proton pumping ATPase inhibitors in oral cavity pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  Sekiya Mizuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Iwate Medical University
Mechanism for ionic environment formation and organelle trafficking by proton-pumping V-ATPase
- Principal Investigator
  
  Nakanishi Mayumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Iwate Medical University
Mechanism of inhibition of ATP synthase by phytopolyphenolsPrincipal Investigator
- Principal Investigator
  
  SEKIYA Mizuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Iwate Medical University
Exploitation of tissue specific proton pump inhibitorsPrincipal Investigator
- Principal Investigator
  
  SEKIYA Mizuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Iwate Medical University
Proton Pumping ATPase and Roles of Acidic pH
- Principal Investigator
  
  FUTAI Masamitsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Iwate Medical University

[Journal Article] F-type proton-pumping ATPase mediates acid tolerance in <i>Streptococcus mutans</i>2023
- Author(s)
  Sekiya Mizuki、Ikeda Kazuya、Yonai Ayaka、Ishikawa Taichi、Shimoyama Yu、Kodama Yoshitoyo、Sasaki Minoru、Nakanishi-Matsui Mayumi
- Journal Title
  
  Journal of Applied Microbiology
  
  Volume: 134 Issue: 4
- DOI
  10.1093/jambio/lxad073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06546, KAKENHI-PROJECT-20K09925, KAKENHI-PROJECT-23K21360
[Journal Article] Proton Pumping ATPases: Rotational Catalysis, Physiological Roles in Oral Pathogenic Bacteria, and Inhibitors2022
- Author(s)
  Sekiya Mizuki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 10 Pages: 1404-1411
- DOI
  10.1248/bpb.b22-00396
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06546
[Journal Article] The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts2022
- Author(s)
  Naomi Matsumoto, Mizuki Sekiya, Ge-Hong Sun-Wada, Yoh Wada, Mayumi Nakanishi-Matsui
- Journal Title
  
  Scientific Reports
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06646
[Journal Article] 多剤耐性菌及び歯周病菌感染症の治療を目指した新たな作用機序による抗菌薬の開発2022
- Author(s)
  阪本泰光, 日高興士, 石原司, 中村彰宏, 鈴木義之, 關谷瑞樹, 六本木沙織, 小笠原渉, 田中信忠
- Journal Title
  
  日本放射光学会誌
  
  Volume: 35(2) Pages: 88-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06546
[Journal Article] The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts2022
- Author(s)
  Matsumoto Naomi、Sekiya Mizuki、Sun-Wada Ge-Hong、Wada Yoh、Nakanishi-Matsui Mayumi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 8455-8455
- DOI
  10.1038/s41598-022-12397-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06546, KAKENHI-PROJECT-21K06553, KAKENHI-PROJECT-19K05950, KAKENHI-PUBLICLY-22H04645, KAKENHI-PUBLICLY-20H05323, KAKENHI-PROJECT-23K21360
[Journal Article] Functional complementation of V-ATPase a subunit isoforms in osteoclasts2020
- Author(s)
  Matsumoto Naomi、Sekiya Mizuki、Fujimoto Yasuyuki、Haga Satoshi、Sun-Wada Ge-Hong、Wada Yoh、Nakanishi-Matsui Mayumi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 4 Pages: 459-466
- DOI
  10.1093/jb/mvaa118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05950, KAKENHI-PROJECT-19K06646, KAKENHI-PROJECT-18K06629, KAKENHI-PROJECT-18K06661, KAKENHI-PROJECT-21K06553, KAKENHI-PUBLICLY-20H05323
[Journal Article] Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase2019
- Author(s)
  YasumitsuSakamoto,YoshiyukiSuzuki,AkihiroNakamura,YurieWatanabe,MizukiSekiya,SaoriRoppongi,ChisatoKushibiki,IppeiIizuka,OsamuTani,HitoshiSakashita,KojiInaka,HiroakiTanaka,MitsuguYamada,KazunoriOhta,NobuyukiHonma,YosukeShida,WataruOgasawara,MayumiNakanishi-Matsui,TakamasaNonaka,HiroakiGouda & NobutadaTanaka
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 13587-13587
- DOI
  10.1038/s41598-019-49984-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06629, KAKENHI-PROJECT-18K06661, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-19H02876
[Journal Article] Proton-pumping F-ATPase plays an important role in Streptococcus mutans under acidic conditions2019
- Author(s)
  Sekiya Mizuki、Izumisawa Shintaro、Iwamoto-Kihara Atsuko、Fan Yang、Shimoyama Yu、Sasaki Minoru、Nakanishi-Matsui Mayumi
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 666 Pages: 46-51
- DOI
  10.1016/j.abb.2019.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06629, KAKENHI-PROJECT-18K06661, KAKENHI-PROJECT-18K09557, KAKENHI-PROJECT-16K07357
[Journal Article] Porphyromonas gingivalis is highly sensitive to inhibitors of a proton-pumping ATPase.2018
- Author(s)
  Mizuki Sekiya, Yu Shimoyama, Taichi Ishikawa, Minoru Sasaki, Masamitsu Futai, Mayumi Nakanishi-Matsui.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 498 Issue: 4 Pages: 837-841
- DOI
  10.1016/j.bbrc.2018.03.066
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17286, KAKENHI-PROJECT-15K07939, KAKENHI-PROJECT-16K18877, KAKENHI-PROJECT-17K11623, KAKENHI-PROJECT-18K09557
[Journal Article] Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment2018
- Author(s)
  Matsumoto N, Sekiya M, Tohyama K, Ishiyama-Matsuura E, Sun-Wada GH, Wada Y, Futai M, Nakanishi-Matsui M.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 6701-6701
- DOI
  10.1038/s41598-018-24918-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07357, KAKENHI-PROJECT-15K07939, KAKENHI-PROJECT-16K18877, KAKENHI-PROJECT-18K06629, KAKENHI-PROJECT-18K06661, KAKENHI-PUBLICLY-16H01201
[Journal Article] Role of α/β interface in F1 ATPase rotational catalysis probed by inhibitors and mutation.2017
- Author(s)
  Sekiya, M., Sakamoto, Y., Futai, M., Nakanishi-Matsui, M.
- Journal Title
  
  Int. J. Biol. Macromol.
  
  Volume: 99 Pages: 615-621
- DOI
  10.1016/j.ijbiomac.2017.02.089
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07939, KAKENHI-PROJECT-16K18877
[Journal Article] ATP Synthase from Escherichia coli: Mechanism of Rotational Catalysis, and Inhibition with the ε Subunit and Phytopolyphenols2016
- Author(s)
  Mayumi Nakanishi-Matsui, Mizuki Sekiya, Masamitsu Futai
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1857 Issue: 2 Pages: 129-140
- DOI
  10.1016/j.bbabio.2015.11.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07939
[Journal Article] Rotating proton pumping ATPases : subunit /subunit interactions and thermodynamics2013
- Author(s)
  M. Nakanishi-Matsui, M. Sekiya, and M. Futai
- Journal Title
  
  IUBMB Life
  
  Volume: 65 Pages: 247-254
- Data Source
  KAKENHI-PROJECT-24790048
[Journal Article] Rotating proton pumping ATPases: Subunit/subunit interactions and thermodynamics.2013
- Author(s)
  M. Nakanishi-Matsui（責任著者）, M. Sekiya, and M. Futai
- Journal Title
  
  IUBMB-Life
  
  Volume: 65 Issue: 3 Pages: 247-254
- DOI
  10.1002/iub.1134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590086, KAKENHI-PROJECT-24790048
[Journal Article] Binding of the phytopolyphenol piceatannol disruptsβ/γsubunit interactions and the rate limiting step of steady state rotational catalysis in the Escherichia coli F_1-ATPase2012
- Author(s)
  M. Sekiya, R. K. Nakamoto, M. Nakanishi-Matsui and M. Futai
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 22771-22780
- Data Source
  KAKENHI-PROJECT-24790048
[Journal Article] Binding of phytopolyphenol piceatannol disrupts β/γ subunit interactions and rate-limiting step of steady state rotational catalysis in Escherichia coli F1-ATPase.2012
- Author(s)
  M. Sekiya, R. K. Nakamoto, M. Nakanishi -Matsui and M. Futai
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 27 Pages: 22771-22780
- DOI
  10.1074/jbc.m112.374868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590086, KAKENHI-PROJECT-24790048
[Journal Article] Rotational catalysis in proton pumping ATPases : from E. coli F-ATPase to mammalian V-ATPase2012
- Author(s)
  M. Futai, M. Nakanishi-Matsui, H. Okamoto, M. Sekiya and R. K. Nakamoto
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1817 Pages: 1711-1721
- Data Source
  KAKENHI-PROJECT-24790048
[Journal Article] Synthesis and innate immunosuppressive effect of 1,2-cyclopentanediol derivatives.2011
- Author(s)
  Kikuchi H., Okazaki K., Sekiya M., Uryu Y., Katou Y., Ueda K., Kurata S., Oshima Y.
- Journal Title
  
  Eur.J.Med.Chem
  
  Volume: 46 Pages: 1263-1273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Synthesis and innate immunosuppressive effect of 1,2-cyclopentanediol derivatives2011
- Author(s)
  Haruhisa Kikuchi, Kaori Okazaki, Mizuki Sekiya, Yasuyuki Uryu, Yasuhiro Katou, Kazunori Ueda, Shoichiro Kurata, Yoshiteru Oshima
- Journal Title
  
  Eur.J.Med.Chem 46
  
  Pages: 1263-1273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Temperature dependence of single molecule rotation of the Escherichia coli ATP synthase F_1 sector reveals the importance of γ-β subunit interactions in the catalytic dwell.2010
- Author(s)
  Sekiya M., Hosokawa H., Nakanishi-Matsui M., Al-Shawi MK., Nakamoto RK., Futai M.
- Journal Title
  
  J Biol.Chem.
  
  Volume: 285 Pages: 42058-42067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] プロトンポンプATPaseの回転触媒機構2010
- Author(s)
  中西真弓、關谷瑞樹
- Journal Title
  
  日本応用酵素協会誌 45
  
  Pages: 11-18
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] The mechanism of rotating proton pumping ATPases.2010
- Author(s)
  M. Nakanishi-Matsui, M. Sekiya, R.K. Nakamoto, M. Futai
- Journal Title
  
  Biochim.Biophys.Acta 1797
  
  Pages: 1343-1352
- Data Source
  KAKENHI-PROJECT-20370048
[Journal Article] Single molecule behavior of inhibited and active state of Escherichia coli ATP synthase F1 rotation2010
- Author(s)
  Mizuki Sekiya, Hiroyuki Hosokawa, Mayumi Nakanishi-Matsui, Robert K. Nakamoto, Marwan K. Al-Shawi, Masamitsu Futai
- Journal Title
  
  J.Biol.Chem 285
  
  Pages: 42058-42067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Single molecule behavior of inhibited and active States of Escherichia coli ATP synthase F_1 rotation.2010
- Author(s)
  M.Sekiya, H.Hosokawa, M.Nakanishi-Matsui, M.K.Al-Shawi, R.K.Nakamoto, M.Futai
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 42058-42067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370048
[Journal Article] The mechanism of rotating proton pumping ATPases.2010
- Author(s)
  M.Nakanishi-Matsui, M.Sekiya, R.K.Nakamoto, M.Futai
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: 1797 Pages: 1343-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370048
[Journal Article] Single molecule behavior of inhibited and active states of Escherichia coli ATP synthase F_1 rotation.2010
- Author(s)
  M. Sekiya, H. Hosokawa, M. Nakanishi Matsui, M.K. Al-Shawi, R.K. Nakamoto, M. Futai
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 42058-42067
- Data Source
  KAKENHI-PROJECT-20370048
[Journal Article] プロトンポンプATPaseの回転触媒機構2010
- Author(s)
  中西真弓、關谷瑞樹
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 45 Pages: 11-18
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] The mechanism of rotating proton pumping ATPases2010
- Author(s)
  Mayumi Nakanishi-Matsui, Mizuki Sekiya, Robert. K. Nakamoto, Masamitsu Futai
- Journal Title
  
  Biochim.Biophys.Acta 1797
  
  Pages: 1343-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Temperature dependence of single molecule rotation of the Escherichia coli ATP synthase F1 sector reveals the importance of γ-β subunit interactions in the catalytic dwell.2009
- Author(s)
  Sekiya M., Nakamoto RK., Al-Shawi MK., Nakanishi-Matsui M., Futai M.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 22401-22410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Revised structure and synthesis of celastramycin a, a potent innate immune suppressor2009
- Author(s)
  Haruhisa Kikuchi, Mizuki Sekiya, Yasuhiro Katou, Kazunori Ueda, Takahiro Kabeya, Shoichiro Kurata, Yoshiteru Oshima
- Journal Title
  
  Org.Lett 11
  
  Pages: 1693-1695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Temperature dependence of single molecule rotation of the Escherichia coli ATP synthase F1 sector reveals the importance of... subunit interactions in the catalytic dwell2009
- Author(s)
  Mizuki Sekiya, Robert K. Nakamoto, Marwan K. Al-Shawi, Mayumi Nakanishi-Matsui, Masamitsu Futai
- Journal Title
  
  J.Biol.Chem 284
  
  Pages: 22401-22410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Journal Article] Temperature dependence of single molecule rotation of the Escherichiacoli ATP synthase F_1 sector reveals the importance of γ-β subunit interactions in the catalytic dwell.2009
- Author(s)
  Mizuki Sekiya, Masamitsu Futai, et al
- Journal Title
  
  J.Biol. Chem. 284
  
  Pages: 22401-22410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370048
[Journal Article] Temperature dependence of single molecule rotation of the Escherichia coli ATP synthase F_1 sector reveals the importance of α・β subunit interactions in the catalytic dwell.2009
- Author(s)
  M. Sekiya, R.K. Nakamoto, M.K. Al-Shawi, M. Nakanishi-Matsui, M. Futai
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 22401-22410
- Data Source
  KAKENHI-PROJECT-20370048
[Journal Article] The mechanism of rotating proton pumping ATPases
- Author(s)
  Nakanishi-Matsui M, Sekiya M, Nakamoto RK, Futai M.
- Journal Title
  
  Biochim.Biophys.Acta (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890239
[Patent] 抗菌性ジペプチド化合物2022
- Inventor(s)
  日高興士、野中由香莉、多部田康一、阪本泰光、關谷瑞樹
- Industrial Property Rights Holder
  日高興士、野中由香莉、多部田康一、阪本泰光、關谷瑞樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-110510
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K06546
[Patent] ペプチド型細菌ジペプチジルペプチダーゼ７阻害剤2018
- Inventor(s)
  日高興士、津田裕子、阪本泰光、關谷瑞樹、小笠原渉
- Industrial Property Rights Holder
  日高興士、津田裕子、阪本泰光、關谷瑞樹、小笠原渉
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] 食道がん高リスク因子となる Streptococcus anginosus のプロトン輸送 F 型 ATPase による耐酸性機構2024
- Author(s)
  関谷瑞樹、小原優良、村松美音、山口友聖、石河太知、下山佑、古玉芳豊、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 食道がん高リスク因子となる口腔内レンサ球菌 Streptococcus anginosus におけるプロトン輸送 A型 ATPaseの役割2024
- Author(s)
  小宅真由、関谷瑞樹、村松美音、山口友聖、下山佑、石河太知、古玉芳豊、佐々木実、中西(松井)真弓
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 食道がん高リスク因子となる Streptococcus anginosus のプロトン輸送 F 型 ATPase による耐酸性機構2024
- Author(s)
  關谷瑞樹、小原優良、村松美音、山口友聖、石河太知、下山佑、古玉芳豊、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] 食道がん高リスク因子となる口腔内レンサ球菌 Streptococcus anginosus におけるプロトン輸送 A型 ATPaseの役割2024
- Author(s)
  小宅真由、關谷瑞樹、村松美音、山口友聖、下山佑、石河太知、古玉芳豊、佐々木実、中西(松井)真弓
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] 虫歯菌 Streptococcus mutans のプロトン輸送 ATPase による耐酸性メカニズム2023
- Author(s)
  関谷瑞樹、池田一弥、米内文香、下山佑、石河太知、古玉芳豊、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] V-ATPase a サブユニットを介したインスリン分泌小胞の輸送2023
- Author(s)
  關谷瑞樹、松元奈緒美、高橋巌、花坂智人、荒木信、那谷耕司、中西（松井）真弓
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] V-ATPase a サブユニットを介したインスリン分泌小胞の輸送2023
- Author(s)
  關谷瑞樹、松元奈緒美、高橋巌、花坂智人、荒木信、那谷耕司、中西（松井）真弓
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] 虫歯菌Streptococcus mutansのプロトン輸送ATPaseによる耐酸性メカニズム2023
- Author(s)
  関谷瑞樹、池田一弥、米内文香、下山佑、石河太知、古玉芳豊、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 破骨細胞において、分泌リソソームに局在するV-ATPaseのa3サブユニットは、Rab7のGEFであるMon1-Ccz1をリクルートする2022
- Author(s)
  松元奈緒美、關谷瑞樹、和田（孫）戈虹、和田洋、中西（松井）真弓
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] インスリン分泌小胞の輸送におけるV-ATPase aサブユニットの役割2022
- Author(s)
  關谷瑞樹、松元奈緒美、高橋巌、荒木信、那谷耕司、中西（松井）真弓
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 口腔レンサ球菌 Streptococcus anginosus のプロトン輸送 ATPase による耐酸性発現メカニズム2022
- Author(s)
  關谷瑞樹、村松美音、山口友聖、下山佑、石河太知、古玉芳豊、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 口腔内病原性レンサ球菌の酸性環境におけるプロトン輸送ATPaseの役割2022
- Author(s)
  關谷瑞樹
- Organizer
  第20回生物化学若手研究セミナー
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] プロトンポンプV-ATPaseのa3サブユニットによる小胞輸送関連因子Mon1-Ccz1の分泌リソソームへのリクルート2022
- Author(s)
  1.後藤（松元）奈緒美、關谷瑞樹、和田（孫）戈虹、和田洋、河上裕、中西（松井）真弓
- Organizer
  第12回国際医療福祉大学学会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] 口腔レンサ球菌 Streptococcus anginosus のプロトン輸送 ATPase による耐酸性発現メカニズム2022
- Author(s)
  關谷瑞樹、村松美音、山口友聖、下山佑、石河太知、古玉芳豊、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] プロトンポンプV-ATPaseのa3サブユニットによる小胞輸送関連因子Mon1-Ccz1の分泌リソソームへのリクルート2022
- Author(s)
  後藤（松元）奈緒美、關谷瑞樹、和田（孫）戈虹、和田洋、河上裕、中西（松井）真弓
- Organizer
  第12回国際医療福祉大学学会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 破骨細胞において、分泌リソソームに局在する V-ATPase の a3 サブユニットは、Rab7のGEFであるMon1-Ccz1をリクルートする2022
- Author(s)
  松元奈緒美、關谷瑞樹、和田（孫）戈虹、和田洋、中西（松井）真弓
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] インスリン分泌小胞の輸送における V-ATPase a サブユニットの役割2022
- Author(s)
  關谷瑞樹、松元奈緒美、高橋巌、荒木信、那谷耕司、中西（松井）真弓
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] Streptococcus anginosus F型プロトン輸送 ATPase の酸性環境における役割2021
- Author(s)
  關谷瑞樹、山口友聖、村松美音、高坂未星、村上幸汰、下山佑、石河太知、古玉芳豊、河野貴久子、矢野志緒、佐々木実、中西（松井）真弓
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] Role of the a2 isoform of V-ATPase in insulin granule trafficking in pancreatic β cells2021
- Author(s)
  M. Sekiya
- Organizer
  V-ATPase summit: from structure and mechanism to cell biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] 多剤耐性菌Stenotrophomonas maltophiliaに抗菌活性を示すジペプチド誘導体の開発2021
- Author(s)
  日高興士、橋本大聖、関拓海、櫻井有紀、阪本泰光、六本木沙織、關谷瑞樹、中村彰宏、鈴木義之、小笠原渉、田中信忠、宮崎杏奈、北條恵子、津田裕子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] Molecular mechanism underlying osteoclast secretory lysosomes mediated by vacuolar-type ATPase2021
- Author(s)
  M. Nakanishi-Matsui, N. Matsumoto, M. Sekiya
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] Molecular mechanism underlying osteoclast secretory lysosomes mediated by vacuolar-type ATPase.2021
- Author(s)
  M. Nakanishi-Matsui, N. Matsumoto, M. Sekiya
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21360
[Presentation] Molecular mechanism underlying osteoclast secretory lysosomes mediated by vacuolar-type ATPase2021
- Author(s)
  M. Nakanishi-Matsui, N. Matsumoto, M. Sekiya
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06646
[Presentation] Streptococcus anginosus F型プロトン輸送 ATPase の酸性環境における役割2021
- Author(s)
  3)關谷瑞樹、山口友聖、村松美音、高坂未星、村上幸汰、下山佑、石河太知、古玉芳豊、河野貴久子、矢野志緒、佐々木実、中西（松井）真弓
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06546
[Presentation] Development of Antimicrobial Dipeptides Targeting Dipeptidyl Peptidase 7 of Stenotrophomonas maltophilia2020
- Author(s)
  Hidaka, K., Hashimoto, T., Seki, T., Sakurai, Y., Sakamoto, Y., Roppongi, S., Sekiya, M., Nakamura, A., Ogasawara, W., Suzuki, Y., Tanaka, N., Miyazaki, A., Hojo, H. and Tsuda, Y.
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] インスリン分泌小胞の輸送における V-ATPase a2 イソフォームの機能2020
- Author(s)
  關谷瑞樹，松元奈緒美，矢野志緒，河野喜久子，中西（松井）真弓
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06646
[Presentation] インスリン分泌小胞の輸送における V-ATPase a2 イソフォームの機能2020
- Author(s)
  關谷瑞樹、松元奈緒美、矢野志緒、河野喜久子、中西（松井）真弓
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] アンギノーサスレンサ球菌の酸性環境におけるプロトン輸送ATPaseの役割2020
- Author(s)
  関谷瑞樹、村上幸汰、高坂未星、松元奈緒美、下山佑、石河太知、河野喜久子、矢野志緒、佐々木実、中西（松井）真弓
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] 細菌DPP7を標的とするジペプチド型阻害剤のSBDDとエステル誘導体の開発2019
- Author(s)
  日高興士、橋本大聖、関拓海、櫻井有紀、中村彰宏、鈴木義之、小笠原渉、六本木沙織、阪本泰光、關谷瑞樹、田中信忠、北條恵子、津田裕子
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] V-ATPase a3 isiform is involved in trafficking of osteoclast secretory lysosomes2019
- Author(s)
  Mayumi Nakanishi-Matsui, Naomi Matsumoto, Mizuki Sekiya, Ge-Hong Sun-Wada, Yoh Wada, Koujiro Tohyama, Eri Ishiyama-Matsuura, Masamitsu Futai
- Organizer
  27th FAOBMB Conference in Kuala Lumpur
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] V-ATPase a3 アイソフォームが関与する分泌リソソームの細胞内輸送機構2019
- Author(s)
  松元奈緒美、關谷瑞樹、遠山稿二郎、石山（松浦）絵里、和田（孫）戈虹、和田洋、二井將光、中西（松井）真弓
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] V-ATPase a3 アイソフォームが関与する分泌リソソームの細胞内輸送機構2019
- Author(s)
  松元奈緒美、關谷瑞樹、遠山稿二郎、石山（松浦）絵里、和田（孫）戈虹、和田洋、二井將光、中西（松井）真弓
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06646
[Presentation] 口腔レンサ球菌の酸性環境におけるプロトン輸送 ATPase の役割2019
- Author(s)
  関谷瑞樹、高坂未星、伊藤槻、櫻直也、泉澤信太郎、楊帆、岩本(木原)昌子、石河太知、下山佑、佐々木実、中西(松井)真弓
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] Streptococcus anginosus の酸性環境におけるプロトン輸送ATPaseの役割2019
- Author(s)
  關谷瑞樹、高坂未星、矢野志緒、河野喜久子、佐々木実、中西（松井）真弓
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] V-ATPase a3 isiform is involved in trafficking of osteoclast secretory lysosomes2019
- Author(s)
  Mayumi Nakanishi-Matsui, Naomi Matsumoto, Mizuki Sekiya, Ge-Hong Sun-Wada, Yoh Wada, Koujiro Tohyama, Eri Ishiyama-Matsuura, Masamitsu Futai
- Organizer
  V-ATPase a3 isiform is involved in trafficking of osteoclast secretory lysosomes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06646
[Presentation] プロトン輸送 ATPase 阻害剤は歯周病菌 P. gingivalis の増殖を阻害する2018
- Author(s)
  關谷瑞樹、下山佑、石河太知、高橋歩実、小田原大樹、佐々木実、二井將光、中西(松井)真弓
- Organizer
  第84回日本生化学会東北支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] Essential role of proton pumping F-ATPase in acid tolerance of Streptococcus mutans2018
- Author(s)
  Sekiya Mizuki, Izumisawa Shintaro, Kushigeta Aki, Haga Masato, Shimoyama Yu, Sasaki Minoru, Kimura Shigenobu, Sasaki Yuka, Iwamoto-Kihara Atsuko, Nakanishi-Matsui Mayumi
- Organizer
  IUBMB SEOUL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] 破骨細胞における分泌リソソームの局在に対するV-ATPase阻害剤（バフィロマイシンA1）の影響2018
- Author(s)
  松元奈緒美、關谷瑞樹、中西（松井）真弓
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18877
[Presentation] V-ATPase a3アイソフォームのリソソーム輸送における機能2018
- Author(s)
  松元奈緒美、關谷瑞樹、遠山稿二郎、石山（松浦）絵里、和田（孫）戈虹、和田洋、二井將光、中西（松井）真弓
- Organizer
  第84回日本生化学会東北支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] プロトン輸送ATPase阻害剤は虫歯菌Streptococcus mutansの耐酸性を低下させる2018
- Author(s)
  關谷瑞樹、泉澤信太郎、櫛桁安生、芳賀雅人、下山佑、佐々木実、木村重信、佐々木由香、岩本昌子、中西（松井）真弓
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18877
[Presentation] プロトン輸送ATPase阻害剤は虫歯菌Streptococcus mutansの耐酸性を低下させる2018
- Author(s)
  關谷瑞樹、泉澤信太郎、櫛桁安生、芳賀雅人、下山佑、佐々木実、木村重信、佐々木由香、岩本昌子、中西（松井）真弓
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] 破骨細胞における分泌リソソームの局在に対するV-ATPase阻害剤（バフィロマイシンA1）の影響2018
- Author(s)
  松元奈緒美、關谷瑞樹、中西（松井）真弓
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] V-ATPase a3アイソフォームは破骨細胞の分泌リソソームの細胞内輸送に必須である2018
- Author(s)
  松元奈緒美、関谷瑞樹、遠山稿二郎、石山（松浦）絵里、和田（孫）戈虹、和田洋、二井將光、中西（松井）真弓
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] プロトン輸送 F-ATPase 阻害剤によるStreptococcus mutans の耐酸性の低下2018
- Author(s)
  關谷瑞樹、泉澤信太郎、櫛桁安生、芳賀雅人、下山佑、石河太知、佐々木実、佐々木由香、岩本(木原)昌子、中西(松井)真弓
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06629
[Presentation] プロトン輸送ATPaseを標的とした抗う蝕化合物の探索2017
- Author(s)
  泉澤信太郎、關谷瑞樹、櫛桁安生、芳賀雅人、下山佑、木村重信、佐々木由香、岩本昌子、中西（松井）真弓
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] Streptococcus mutansの耐酸性におけるF-ATPaseの重要性2017
- Author(s)
  關谷瑞樹、泉澤信太郎、櫛桁安生、芳賀雅人、下山佑、佐々木実、木村重信、佐々木由香、岩本昌子、中西（松井）真弓
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K18877
[Presentation] Streptococcus mutansの耐酸性におけるF-ATPaseの重要性2017
- Author(s)
  關谷瑞樹、泉澤信太郎、櫛桁安生、芳賀雅人、下山佑、佐々木実、木村重信、佐々木由香、岩本昌子、中西（松井）真弓
- Organizer
  ConBio2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] プロトン輸送ATPaseを標的とした抗う蝕化合物の探索2017
- Author(s)
  泉澤信太郎、關谷瑞樹、櫛桁安生、芳賀雅人、下山佑、木村重信、佐々木由香、岩本昌子、中西（松井）真弓
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16K18877
[Presentation] F1-ATPaseの回転触媒機構に置けるα/β相互作用の役割2016
- Author(s)
  關谷瑞樹、山野辺春香、千葉瑛子、佐藤桃恵、河野富一、大橋暁香、小川智、山越博幸、岩渕俊治、二井將光、中西（松井）真弓
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] プロトン輸送ATPaseを標的とする抗歯周病化合物の探索2016
- Author(s)
  関谷瑞樹、高橋歩実、小田原大樹、下山佑、木村重信、中西（松井）真弓
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] 破骨細胞に特徴的なリソソームの局在におけるV-ATPase a3イソフォームの関与2016
- Author(s)
  松元奈緒美、關谷瑞樹、遠山稿二郎、孫（和田）戈虹、和田洋、二井將光、中西（松井）真弓
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] クルクミン類による ATP 合成酵素阻害作用2016
- Author(s)
  關谷瑞樹、山野辺春香、千葉瑛子、佐藤桃恵、河野富一、大橋暁香、小川智、山越博幸、岩渕俊治、二井將光、中西（松井）真弓
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-16K18877
[Presentation] F1-ATPaseの回転触媒機構に置けるα/β相互作用の役割2015
- Author(s)
  関谷瑞樹、中山華緒里、鈴木彩香、二井將光、中西（松井）真弓
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] プロトン輸送ATPaseの阻害剤による抗歯周病菌作用2015
- Author(s)
  関谷瑞樹、高橋歩実、小田原大樹、下山佑、木村重信、中西（松井）真弓
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  岩手県紫波郡矢巾
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-15K07939
[Presentation] ポリエンα-ピロンによるATP合成酵素阻害メカニズム2014
- Author(s)
  關谷瑞樹、鈴木彩香、二井將光、中西(松井)真弓
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] クルクミンによるATP合成酵素阻害メカニズムの解析2013
- Author(s)
  關谷瑞樹、久坂亮介、西山枝里、千葉瑛子、佐藤桃恵、岩本(木原)昌子、二井將光、中西(松井)真弓
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] クルクミンによるATP合成酵素の阻害機構の解析2013
- Author(s)
  久坂亮介、關谷瑞樹、千葉瑛子、佐藤桃恵、岩本(木原)昌子、中西(松井)真弓、二井將光
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] ポリフェノール類によるATP合成酵素阻害メカニズムの解析2013
- Author(s)
  關谷瑞樹、Robert K. Nakamoto、吉田秀成、西山枝里、(松井)真弓、二井將光
- Organizer
  FAOBMB Mini-Symposium
- Place of Presentation
  岩手矢巾
- Year and Date
  2013-04-06
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] クルクミン類縁体によるATP合成酵素の阻害作用2013
- Author(s)
  千葉瑛子、佐藤桃恵、關谷瑞樹、久坂亮介、山越博幸、高山亜紀、柴田浩行、中西(松井)真弓、岩渕好治、二井將光
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] 一分子観察によるポリフェノール類のATP合成酵素阻害機構2012
- Author(s)
  關谷瑞樹、Robert K. Nakamoto、中西(松井)真弓、二井將光
- Organizer
  生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] 大腸菌ATP合成酵素におけるεサブユニットの役割2011
- Author(s)
  関谷瑞樹
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] 大腸菌ATP合成酵素におけるεサブユニットの役割2011
- Author(s)
  関谷瑞樹, 中西(松井)真弓, 西山枝里, R.K.Nakamoto, M.K.Al-Shawi, 二井將光
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡((東北関東大震災のため中止) 当初の予定)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] The intrinsic inhibition of ATP hydrolysis in E.coli ATP synthase : Single molecule observation2010
- Author(s)
  Sekiya M., Hosokawa H., Nakanishi-Matsui M., Al-Shawi MK., Nakamoto RK., Futai M.
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Effect of ε subunit on F_1 rotation in E.coli ATP synthase.2010
- Author(s)
  關谷瑞樹, 西山枝里, R.K.Nakamoto, 中西(松井)真弓, 二井將光
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Effect of ε subunit on F_1 rotation in E.coli ATP synthase2010
- Author(s)
  関谷瑞樹, 西山枝里, Robert K., Nakamoto, 中西(松井)真弓, 二井將光
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] 大腸菌ATP合成酵素によるATP加水分解反応の阻害機構2010
- Author(s)
  関谷瑞樹
- Organizer
  日本薬学会第130年会
- Place of Presentation
  就実大学(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] 大腸菌 ATP 合成酵素によるATP 加水分解反応の阻害機構2010
- Author(s)
  関谷瑞樹、細川浩之、中西(松井)真弓、二井將光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  就実大学(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Thermodynamics of single molecule rotation of Escherichia coli F-ATPase2010
- Author(s)
  Sekiya M., Hosokawa H., Nakanishi-Matsui M., Al-Shawi MK., Nakamoto RK., Futai M.
- Organizer
  2010 FASEB Summer Research Conferences Transport ATPases : From Molecules to Maladies
- Place of Presentation
  Snowmass Village, Colorado
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Single molecule detection of an intrinsic inhibited state of the E. coli F_1 ATPase2010
- Author(s)
  関谷瑞樹, 細川浩之, Robert K., Nakamoto, Marwan K., Al-Shawi, 中西(松井)真弓, 二井將光
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] 大腸菌ATP合成酵素によるATP加水分解反応の阻害機構2010
- Author(s)
  関谷瑞樹、細川浩之、中西(松井)真弓、二井將光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山県就実大学
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] The intrinsic inhibition mechanism of ATP hydrolysis in ATP synthase : Single molecule observation.2010
- Author(s)
  関谷瑞樹
- Organizer
  FAOBMB Symposium (OzBio2010)
- Place of Presentation
  Melbourne
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Single molecule detection of an intrinsic inhibited state of the E. coli F_1 ATPase2010
- Author(s)
  関谷瑞樹
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] 大腸菌ATP合成酵素におけるεサブユニットの役割2010
- Author(s)
  関谷瑞樹, 中西(松井)真弓, 西山枝里, Robert K., Nakamoto, Marwan K., Al-Shawi, 二井將光
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡(東日本大震災のため中止)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] The intrinsic inhibition mechanism of ATP hydrolysis in ATP synthase : Single molecule observation.2010
- Author(s)
  関谷瑞樹, 細川浩之, 中西(松井)真弓, 二井將光
- Organizer
  FAOBMB Symposium (OzBio2010)
- Place of Presentation
  Melbourne
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] The intrinsic inhibition mechanism of ATP hydrolysis in ATP synthase : Single molecule observation2010
- Author(s)
  Sekiya M., Hosokawa H., Nakanishi-Matsui M., Futai M.
- Organizer
  OZBIO2010
- Place of Presentation
  Melbourne Convention & Exhibition Centre
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] 大腸菌ATP合成酵素によるATP加水解反応の阻害機構2010
- Author(s)
  關谷瑞樹, 中西(松井)真弓, 二井將光, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  就実大学(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Thermodynamics of single molecule rotation of Escherichia coli F-ATPase.2010
- Author(s)
  M.Sekiya, H.Hosokawa, R.K.Nakamoto, M.K.Al-Shawi, M.Nakanishi-Matsui, M.Futai
- Organizer
  FASEB Summer research conferences
- Place of Presentation
  Colorado, USA
- Year and Date
  2010-06-09
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Al-Shawi, Mayumi Nakanishi-Matsui, and Masamitsu Futai,Thermodynamics of single molecule rotation of Escherichia coli F-ATPase.2010
- Author(s)
  Mizuki Sekiya, Hiroyuki Hosokawa, Robert K. Nakamoto, Marwan K.
- Organizer
  FASEB Summer research conferences
- Place of Presentation
  Colorado,USA.
- Year and Date
  2010-06-09
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] The intrinsic inhibition mechanism of ATP hydrolysis in ATP synthase : Single molecule observation.2010
- Author(s)
  M.Sekiya, H.Hosokawa, M.Nakanishi-Matsui, M.Futai
- Organizer
  FAOBMB Symposium(OzBio2010)
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Effect of ε subunit on F_1 rotation in E. coli ATP synthase2010
- Author(s)
  関谷瑞樹
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Single molecule detection of an intrinsic inhibited state of the E.coli F_1 ATPase2010
- Author(s)
  關谷瑞樹, 細川浩之, Robert K.Nakamoto, Marwan K.Al-Shawi, 中西(松井)真弓, 二井將光
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Thermodynamics of single molecule rotation of proton pumping ATPase2009
- Author(s)
  関谷瑞樹
- Organizer
  21st IUBMB and the 12th FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  上海国際会議センター
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Thermodynamics of single molecule rotation of Escherichia coli ATP synthase.2009
- Author(s)
  関谷瑞樹
- Organizer
  JBS Biofrontier Symposium on Biochemistry of pH Homeostasis and Proton Circuit
- Place of Presentation
  岩手医科大学矢巾キャンパス
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ATP合成酵素の回転における熱力学とβ-γサブユニット間の相互作用による影響2009
- Author(s)
  關谷瑞樹、中西(松井)真弓、二井將光
- Organizer
  生化学会東北支部会
- Place of Presentation
  東北大学片平さくらホール
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] ATP合成酵素の回転におけるβ-γサブユニット間相互作用の影響2009
- Author(s)
  関谷瑞樹
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ATP 合成酵素の回転における熱力学と γ.β サブユニット間の相互作用の重要性2009
- Author(s)
  関谷瑞樹, Robert K., Nakamoto, Marwan K., Al-Shawi, 中西(松井)真弓, 二井將光
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] ATP合成酵素の回転における熱力学とγ-βサブユニット間の相互作用の重要性2009
- Author(s)
  関谷瑞樹
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Thermodynamics of Escherichia coli ATP synthase F_1 sector rotation and effects of γ subunit Met23 replacement.2009
- Author(s)
  関谷瑞樹
- Organizer
  Iwate International Symposium on Biochemical Approaches to Drug Discovery
- Place of Presentation
  岩手医科大学矢巾キャンパス
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ATP合成酵素の回転における熱力学とγ-βサブユニット間の相互作用の重要性2009
- Author(s)
  關谷瑞樹, Robert K.Nakamoto, MarwanK.AI-Shawi, 中西(松井)真弓, 二井將光
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Thermodynamics of single molecule rotation of Escherichia coli ATP synthase2009
- Author(s)
  Mizuki Sekiya
- Organizer
  JBS Biofrontier Symposium on Biochemistry of pH Homeostasis and Proton Circuit
- Place of Presentation
  岩手医科大学矢巾キャンパス
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Thermodynamics of single molecule rotation of proton pumping ATPase2009
- Author(s)
  関谷瑞樹
- Organizer
  21st IUBMB and the 12th FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  上海国際会議センター
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Thermodynamics of Escherichia coli ATP synthase F1 sector rotation and effects of γ subunit Met23 replacement.2009
- Author(s)
  関谷瑞樹
- Organizer
  Iwate International Symposium on Biochemical Approaches to Drug Discovery
- Place of Presentation
  岩手医科大学矢巾キャンパス
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Pauses of subunit rotation of Escherichia coli ATP synthase F_1 Sector.2009
- Author(s)
  細川浩之, 中西(松井)真弓, 関谷瑞樹, 二井將光
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] ATP 合成酵素の回転における熱力学と β.γ サブユニット間の相互作用による影響2009
- Author(s)
  関谷瑞樹、中西(松井)真弓、二井將光
- Organizer
  生化学会東北支部会
- Place of Presentation
  東北大学片平さくらホール
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] ATP合成酵素の回転におけるβ-αサブユニット間相互作用の影響(口頭)2009
- Author(s)
  関谷瑞樹
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Thermodynamics of single molecule rotation of Escherichia coli ATP synthase.2009
- Author(s)
  関谷瑞樹
- Organizer
  JBS Biofrontier Symposium on Biochemistry of pH Homeostasis and Proton Circuit
- Place of Presentation
  岩手医科大学矢巾キャンパス
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] ATP合成酵素の回転における熱力学とβ-γサブユニット間の相互作用による影響2009
- Author(s)
  関谷瑞樹
- Organizer
  生化学会東北支部会
- Place of Presentation
  東北大学片平さくらホール
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] Thermodynamics of single molecule rotation of proton pumping ATPase2009
- Author(s)
  Mizuki Sekiya
- Organizer
  21st IUBMB and the 12th FAOBMB Internationa I Congress of Biochemistry and Molecular Biology
- Place of Presentation
  上海国際会議センター
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] Thermodynamics of Escherichia coli ATP Synthase F_1 Sector Rotation and Effects of γ Subunit Met23 Replacement2009
- Author(s)
  Mizuki Sekiya
- Organizer
  Iwate International Symposium on Biochemical Approaches to Drug Discovery
- Place of Presentation
  岩手医科大学矢巾キャンパス
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21890239
[Presentation] The effects of γ subunit Met23 replacement on ATP synthase F_1 sector rotation. (口頭)2008
- Author(s)
  関谷瑞樹
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ATP合成酵素のβ-γサブユニット間相互作用による回転への影響(口頭)2008
- Author(s)
  関谷瑞樹
- Organizer
  第47回日本薬学会東北支部大会
- Place of Presentation
  岩手
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ATP合成酵素のβ-γサブユニット間相互作用による回転への影響2008
- Author(s)
  関谷瑞樹
- Organizer
  第47回日本薬学会東北支部大会
- Place of Presentation
  岩手
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] The effects of γ subunit Met23 replacement on ATP synthase F_1 sector rotation.2008
- Author(s)
  関谷瑞樹
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] The effect of γ subunit Met23 replacement on ATP synthase F1 sector rotation.2008
- Author(s)
  関谷瑞樹
- Organizer
  Mini-Symposium on Proton Pumping ATPases-Iwate-Oxford Collaboration
- Place of Presentation
  岩手医科大学
- Year and Date
  2008-09-22
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ポリエン α-ピロンによるATP 合成酵素阻害メカニズム
- Author(s)
  〇關谷瑞樹、鈴木彩香、二井將光、中西（松井）真弓
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] クルクミンによるATP合成酵素阻害メカニズムの解析
- Author(s)
  〇關谷瑞樹、久坂亮介、西山枝里、千葉瑛子、佐藤桃恵、岩本（木原）昌子、二井將光、中西（松井）真弓
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790048
[Presentation] Thermodynamics of single molecule rotation of Escherichia coli F-ATPase.
- Author(s)
  関谷瑞樹
- Organizer
  FASEB Summer research conferences
- Place of Presentation
  Colorado, USA
- Data Source
  KAKENHI-PROJECT-20370048
[Presentation] ポリフェノール類によるATP合成酵素阻害メカニズムの解析
- Author(s)
  〇關谷瑞樹、Robert K. Nakamoto、吉田秀成、西山枝里、（松井）真弓、二井將光
- Organizer
  FAOBMB Mini-Symposium
- Place of Presentation
  岩手矢巾
- Data Source
  KAKENHI-PROJECT-24790048

1. GOTO Naomi (80403971)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. NAKANISHI Mayumi (20270506)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
3. FUTAI Masamitsu (50012646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
4. WADA GE-HONG (00314427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. WADA YOH (50212329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. Wu Yibo (50811618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岩本昌子

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 佐々木実

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 阪本泰光

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIKAWA Taichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 孫戈虹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sekiya Mizuki 關谷 瑞樹

SEKIYA Mizuki 關谷 瑞樹

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嫌気性病原菌におけるアーキア型プロトン輸送ATPaseの作動機構と生理学的役割Principal Investigator

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Ion transport network in oral pathogenic bacteriaPrincipal Investigator

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Mechanism underlying organelle trafficking regulated through structual diversity of proton pump V-ATPase

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Common principle of secretory lysosome transport and universal mechanism of organelle trafficking

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A novel approach to drug development targeting to proton pumping ATPasePrincipal Investigator

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Exploitation of proton pumping ATPase inhibitors in oral cavity pathogenic bacteriaPrincipal Investigator

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Mechanism for ionic environment formation and organelle trafficking by proton-pumping V-ATPase

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Mechanism of inhibition of ATP synthase by phytopolyphenolsPrincipal Investigator

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Exploitation of tissue specific proton pump inhibitorsPrincipal Investigator

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Proton Pumping ATPase and Roles of Acidic pH

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[Journal Article] F-type proton-pumping ATPase mediates acid tolerance in <i>Streptococcus mutans</i>2023

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[Journal Article] Proton Pumping ATPases: Rotational Catalysis, Physiological Roles in Oral Pathogenic Bacteria, and Inhibitors2022

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[Journal Article] The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts2022

Author(s)

Sekiya Mizuki 關谷瑞樹

SEKIYA Mizuki 關谷瑞樹