Okada Masashi 岡田雅司

… Alternative Names

OKADA MASASHI 岡田雅司

OKADA Masashi 岡田雅司

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Researcher Number	70512614
Other IDs
Affiliation (Current)	2025: 山形大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 山形大学, 医学部, 准教授 2014 – 2021: 山形大学, 医学部, 講師 2011 – 2012: 山形大学, 医学部, 講師 2008 – 2012: Yamagata University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Emergency medicine / Tumor therapeutics / Tumor biology Except Principal Investigator Neurosurgery / General anatomy (including Histology/Embryology)
Keywords	Principal Investigator がん幹細胞 / 分化誘導 / ドラッグリポジショニング / 幹細胞性 / xenograft / JNK / 腫瘍発生 / ストレス / シグナル伝達 / DGK … More / ユビキチン / 虚血 / エピジェネティック / エピジェネティック修飾薬 / 細胞毒性 / HDAC / 葉酸代謝 / 分化 / 代謝 / OXPHOS / 酸化的リン酸化 / MLK / 癌幹細胞 / 適応拡大 / Kras / 薬剤抵抗性 / ROS / NAP / 核-細胞質間輸送 / 神経細胞死 / macrophage / Rac1 / IQGAP / phagocytosis / Rb / cell cycle re-entry / リン脂質代謝酵素 / ポリユビキチン化 / 細胞周期 / イノシトールリン脂質 / PC12 / 神経細胞 / 細胞死 / タンパク質分解 / リン脂質 / 低酸素 … More Except Principal Investigator 神経膠芽腫 / glioma-initiating cell / グリオーマ / Tumor-initiating cell / Tumor-initiating cells / glioma-initiating cells / 細胞死 / 海馬ニューロン / 酸素グルコース欠乏 / 細胞組織化学 / がん細胞 / イノシトールリン脂質 / プロテアソーム / 核 / p53 / アポトーシス / 脂質代謝酵素 / ストレス応答 / 細胞周期 Less

がん幹細胞のアキレス腱としてのエピジェネティック修飾を標的とする新規治療法の確立Principal Investigator
- Principal Investigator
  
  岡田雅司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Yamagata University
Development of novel anti-cancer stem cell therapeutic strategies targeting oxidative phosphorylationPrincipal Investigator
- Principal Investigator
  
  Okada Masashi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Yamagata University
Trial to establish new cancer stem cell targeting therapy utilizing drug repositioningPrincipal Investigator
- Principal Investigator
  
  Okada Masashi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Yamagata University
Taking advantage of a pitfall in glioma cancer stem cell epigenetics to develop novel therapies directed to cancer stem cells
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Yamagata University
An attempt to answer the cardinal question --- why do cancer cells have such a sweet tooth? --- through glioma stem cell research
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Yamagata University
The impact of JNK activity on the cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Okada Masashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Yamagata University
An attempt to create an animal model for glioblastoma cure via proving the hypothesis that glucose metabolism serves as a rheostat to determine the cell fate of cancer stem cells
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Yamagata University
Functional analysis of phospholipid-metabolizing enzyme signal transduction during early phase of cell death after ischemiaPrincipal Investigator
- Principal Investigator
  
  MASASHI Okada
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamagata University
Functional role of lipid second messenger metabolizing enzyme in cell cycle and stress response
- Principal Investigator
  
  GOTO Kaoru
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Yamagata University
Functional analysis of phospholipid metabolizing enzymes during cell death after ischemiaPrincipal Investigator
- Principal Investigator
  
  OKADA Masashi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamagata University

[Journal Article] Domatinostat Targets the FOXM1?Survivin Axis to Reduce the Viability of Ovarian Cancer Cells Alone and in Combination with Chemotherapeutic Agents2023
- Author(s)
  Nakagawa-Saito Yurika、Mitobe Yuta、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 13 Pages: 10817-10817
- DOI
  10.3390/ijms241310817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Givinostat Inhibition of Sp1-dependent MGMT Expression Sensitizes Glioma Stem Cells to Temozolomide.2023
- Author(s)
  Nakagawa-Saito Y, Mitobe Y, Togashi K, Suzuki S, Sugai A, Kitanaka C, Okada M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 3 Issue: 3 Pages: 1131-1138
- DOI
  10.21873/anticanres.16258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-21K16867, KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-21H03040
[Journal Article] The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo2023
- Author(s)
  Mitobe Yuta、Suzuki Shuhei、Nakagawa-Saito Yurika、Togashi Keita、Sugai Asuka、Sonoda Yukihiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 7 Pages: 1967-1967
- DOI
  10.3390/biomedicines11071967
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] CEP-1347 Dually Targets MDM4 and PKC to Activate p53 and Inhibit the Growth of Uveal Melanoma Cells2023
- Author(s)
  Togashi Keita、Suzuki Shuhei、Mitobe Yuta、Nakagawa-Saito Yurika、Sugai Asuka、Takenouchi Senri、Sugimoto Masahiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 1 Pages: 118-118
- DOI
  10.3390/cancers16010118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Antagonizing MDM2 Overexpression Induced by MDM4 Inhibitor CEP-1347 Effectively Reactivates Wild-Type p53 in Malignant Brain Tumor Cells2023
- Author(s)
  Mitobe Yuta、Suzuki Shuhei、Nakagawa-Saito Yurika、Togashi Keita、Sugai Asuka、Sonoda Yukihiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 17 Pages: 4326-4326
- DOI
  10.3390/cancers15174326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867, KAKENHI-PROJECT-21H03040
[Journal Article] HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny2022
- Author(s)
  Nakagawa-Saito Yurika、Saitoh Shinichi、Mitobe Yuta、Sugai Asuka、Togashi Keita、Suzuki Shuhei、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8084-8084
- DOI
  10.3390/ijms23158084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-21K16867, KAKENHI-PROJECT-21H03040, KAKENHI-PROJECT-19K09449
[Journal Article] CEP-1347 Targets MDM4 Protein Expression to Activate p53 and Inhibit the Growth of Glioma Cells.2022
- Author(s)
  Mitobe Y, Nakagawa-Saito Y, Togashi K, Suzuki S, Sugai A, Matsuda KI, Sonoda Y, Kitanaka C, Okada M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 10 Issue: 10 Pages: 4727-4733
- DOI
  10.21873/anticanres.15977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-21K16867, KAKENHI-PROJECT-21H03040, KAKENHI-PROJECT-19K09449
[Journal Article] Inhibition of the Phospholipase Cε-c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties2022
- Author(s)
  Okada Masashi、Nakagawa-Saito Yurika、Mitobe Yuta、Sugai Asuka、Togashi Keita、Suzuki Shuhei、Kitanaka Chifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8785-8785
- DOI
  10.3390/ijms23158785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-21K16867, KAKENHI-PROJECT-21H03040, KAKENHI-PROJECT-19K09449
[Journal Article] Targeting Folate Metabolism Is Selectively Cytotoxic to Glioma Stem Cells and Effectively Cooperates with Differentiation Therapy to Eliminate Tumor-Initiating Cells in Glioma Xenografts2021
- Author(s)
  Okada Masashi、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Yamamoto Masahiro、Kitanaka Chifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11633-11633
- DOI
  10.3390/ijms222111633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-21H03040, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Gemcitabine radiosensitization primes irradiated malignant meningioma cells for senolytic elimination by navitoclax2021
- Author(s)
  Yamamoto Masahiro、Sanomachi Tomomi、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Seino Shizuka、Sato Atsushi、Okada Masashi、Kitanaka Chifumi
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: 3 Issue: 1 Pages: 1-11
- DOI
  10.1093/noajnl/vdab148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-20K17949, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Inhibition of the Lipid Droplet-Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties.2021
- Author(s)
  Kuramoto K, Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Kitanaka C, Okada M.
- Journal Title
  
  Genes (Basel)
  
  Volume: 12(1) Issue: 1 Pages: 99-99
- DOI
  10.3390/genes12010099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Roles for hENT1 and dCK in gemcitabine sensitivity and malignancy of meningioma2021
- Author(s)
  Yamamoto Masahiro、Sanomachi Tomomi、Suzuki Shuhei、Uchida Hiroyuki、Yonezawa Hajime、Higa Nayuta、Takajo Tomoko、Yamada Yuki、Sugai Asuka、Togashi Keita、Seino Shizuka、Okada Masashi、Sonoda Yukihiko、Hirano Hirofumi、Yoshimoto Koji、Kitanaka Chifumi
- Journal Title
  
  Neuro-Oncology
  
  Volume: XX Issue: 6 Pages: 1-10
- DOI
  10.1093/neuonc/noab015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17949, KAKENHI-PROJECT-18K16550, KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-20K07631
[Journal Article] Dexamethasone Sensitizes Cancer Stem Cells to Gemcitabine and 5-Fluorouracil by Increasing Reactive Oxygen Species Production through NRF2 Reduction2021
- Author(s)
  Suzuki Shuhei、Yamamoto Masahiro、Sanomachi Tomomi、Togashi Keita、Sugai Asuka、Seino Shizuka、Yoshioka Takashi、Okada Masashi、Kitanaka Chifumi
- Journal Title
  
  Life
  
  Volume: 11 Issue: 9 Pages: 885-885
- DOI
  10.3390/life11090885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Lurasidone Sensitizes Cancer Cells to Osimertinib by Inducing Autophagy and Reduction of Survivin2021
- Author(s)
  SUZUKI SHUHEI、YAMAMOTO MASAHIRO、SANOMACHI TOMOMI、TOGASHI KEITA、SEINO SHIZUKA、SUGAI ASUKA、YOSHIOKA TAKASHI、OKADA MASASHI、KITANAKA CHIFUMI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 9 Pages: 4321-4331
- DOI
  10.21873/anticanres.15237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway.2020
- Author(s)
  Togashi K, Okada M, Suzuki S, Sanomachi T, Seino S, Yamamoto M, Yamashita H, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 40(9) Issue: 9 Pages: 4961-4968
- DOI
  10.21873/anticanres.14499
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1?JNK axis2020
- Author(s)
  Suzuki Shuhei、Okada Masashi、Sanomachi Tomomi、Togashi Keita、Seino Shizuka、Sato Atsushi、Yamamoto Masahiro、Kitanaka Chifumi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 52 Pages: 18328-18342
- DOI
  10.1074/jbc.ra120.015223
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells2020
- Author(s)
  Kuramoto Kenta、Yamamoto Masahiro、Suzuki Shuhei、Sanomachi Tomomi、Togashi Keita、Seino Shizuka、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  The FEBS Journal
  
  Volume: Epub ahead of print Issue: 10 Pages: 2023-2036
- DOI
  10.1111/febs.15187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02908, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing2020
- Author(s)
  Suzuki Shuhei、Yamamoto Masahiro、Sanomachi Tomomi、Togashi Keita、Sugai Asuka、Seino Shizuka、Okada Masashi、Yoshioka Takashi、Kitanaka Chifumi
- Journal Title
  
  Biomedicines
  
  Volume: 8 Issue: 8 Pages: 273-273
- DOI
  10.3390/biomedicines8080273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-18H02908
[Journal Article] In vitro and in vivo Anti-Tumor Effects of Brexpiprazole, a Newly-Developed Serotonin-Dopamine Activity Modulator With an Improved Safety Profile2019
- Author(s)
  Shuhei Suzuki, Masahiro Yamamoto, Keita Togashi, Tomomi Sanomachi, Asuka Sugai, Shizuka Seino, Takashi Yoshioka, Chifumi Kitanaka, Masashi Okada
- Journal Title
  
  Oncotarget
  
  Volume: 37 Issue: 37 Pages: 3547-3558
- DOI
  10.18632/oncotarget.26949
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-17K15015
[Journal Article] Brexpiprazole, a Serotonin-Dopamine Activity Modulator, Can Sensitize Glioma Stem Cells to Osimertinib, a Third-Generation EGFR-TKI, via Survivin Reduction2019
- Author(s)
  Suzuki Shuhei、Yamamoto Masahiro、Sanomachi Tomomi、Togashi Keita、Sugai Asuka、Seino Shizuka、Yoshioka Takashi、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Cancers
  
  Volume: 11 Issue: 7 Pages: 947-947
- DOI
  10.3390/cancers11070947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-17K15015
[Journal Article] Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs2019
- Author(s)
  Sanomachi Tomomi、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Seino Shizuka、Okada Masashi、Yoshioka Takashi、Kitanaka Chifumi、Yamamoto Masahiro
- Journal Title
  
  Cancers
  
  Volume: 11 Issue: 10 Pages: 1550-1550
- DOI
  10.3390/cancers11101550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-16K07160
[Journal Article] Brexpiprazole Reduces Survivin and Reverses EGFR Tyrosine Kinase Inhibitor Resistance in Lung and Pancreatic Cancer2019
- Author(s)
  Tomomi Sanomachi, Shuhei Suzuki, Keita Togashi, Shizuka Seino, Takashi Yoshioka, Chifumi Kitanaka , Masashi Okada, Masahiro Yamamoto
- Journal Title
  
  Anticancer Res
  
  Volume: 9 Issue: 9 Pages: 4817-4828
- DOI
  10.21873/anticanres.13667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-17K15015
[Journal Article] AS602801 Sensitizes Ovarian Cancer Stem Cells to Paclitaxel by Down-regulating MDR1.2019
- Author(s)
  Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Issue: 2 Pages: 609-617
- DOI
  10.21873/anticanres.13154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07160
[Journal Article] Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells.2018
- Author(s)
  Suzuki S, Okada M, Takeda H, Kuramoto K, Sanomachi T, Togashi K, Seino S, Yamamoto M, Yoshioka T, Kitanaka C.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 66 Pages: 32667-32679
- DOI
  10.18632/oncotarget.25994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-17K15015
[Journal Article] AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes.2018
- Author(s)
  Kuramoto K, Yamamoto M, Suzuki S, Sanomachi T, Togashi K, Seino S, Kitanaka C, Okada M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Issue: 9 Pages: 5093-5099
- DOI
  10.21873/anticanres.12829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07160
[Journal Article] A Small-molecule Kinase Inhibitor, CEP-1347, Inhibits Survivin Expression and Sensitizes Ovarian Cancer Stem Cells to Paclitaxel.2018
- Author(s)
  Togashi K, Okada M, Yamamoto M, Suzuki S, Sanomachi T, Seino S, Yamashita H, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Issue: 8 Pages: 4535-4542
- DOI
  10.21873/anticanres.12757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-18H03188
[Journal Article] AS602801, an Anticancer Stem Cell Candidate Drug, Reduces Survivin Expression and Sensitizes A2780 Ovarian Cancer Stem Cells to Carboplatin and Paclitaxel.2018
- Author(s)
  Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Issue: 12 Pages: 6699-6706
- DOI
  10.21873/anticanres.13038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07160
[Journal Article] Olanzapine, an Atypical Antipsychotic, Inhibits Survivin Expression and Sensitizes Cancer Cells to Chemotherapeutic Agents.2017
- Author(s)
  Sanomachi T, Suzuki S, Kuramoto K, Takeda H, Sakaki H, Togashi K, Seino S, Yoshioka T, Okada M, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Issue: 11 Pages: 6177-6188
- DOI
  10.21873/anticanres.12067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-17K15015
[Journal Article] Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug.2017
- Author(s)
  Okada M, Takeda H, Sakaki H, Kuramoto K, Suzuki S, Sanomachi T, Togashi K, Seino S, Kitanaka C.
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Issue: 55 Pages: 94872-94882
- DOI
  10.18632/oncotarget.22033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-16K15640, KAKENHI-PROJECT-16K18410, KAKENHI-PROJECT-15H04946
[Journal Article] Antitumor activity of gemcitabine against high-grade meningioma in vitro and in vivo.2017
- Author(s)
  Takeda H, Okada M, Kuramoto K, Suzuki S, Sakaki H, Sanomachi T, Seino S, Yoshioka T, Hirano H, Arita K, Kitanaka C.
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Issue: 53 Pages: 90996-91008
- DOI
  10.18632/oncotarget.18827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-15K10338, KAKENHI-PROJECT-16K18410
[Journal Article] Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction.2017
- Author(s)
  Kuramoto K, Suzuki S, Sakaki H, Takeda H, Sanomachi T, Seino S, Narita Y, Kayama T, Kitanaka C, Okada M.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 7 Issue: 6 Pages: 835-844
- DOI
  10.1002/2211-5463.12226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-16K15640, KAKENHI-PROJECT-16K18410, KAKENHI-PROJECT-15H04946
[Journal Article] Aripiprazole, an Antipsychotic and Partial Dopamine Agonist, Inhibits Cancer Stem Cells and Reverses Chemoresistance.2016
- Author(s)
  Suzuki S, Okada M, Kuramoto K, Takeda H, Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 10 Issue: 10 Pages: 5153-5161
- DOI
  10.21873/anticanres.11085
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-16K18410
[Journal Article] Reciprocal regulation of p53 and NF-κB by diacylglycerol kinase ζ.2016
- Author(s)
  Tanaka T, Tsuchiya R, Hozumi Y, Nakano T, Okada M, Goto K.
- Journal Title
  
  Adv Biol Regul.
  
  Volume: 60 Pages: 15-21
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] Impact of H3K27 Demethylase Inhibitor GSKJ4 on NSCLC Cells Alone and in Combination with Metformin.2016
- Author(s)
  Watarai H, Okada M, Kuramoto K, Takeda H, Sakaki H, Suzuki S, Seino S, Oizumi H, Sadahiro M, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 11 Issue: 11 Pages: 6083-6092
- DOI
  10.21873/anticanres.11198
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07160
[Journal Article] Rho-Associated Protein Kinase (ROCK) Inhibitors Inhibit Survivin Expression and Sensitize Pancreatic Cancer Stem Cells to Gemcitabine.2016
- Author(s)
  Takeda H, Okada M, Suzuki S, Kuramoto K, Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 12 Issue: 12 Pages: 6311-6318
- DOI
  10.21873/anticanres.11227
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-16K18410
[Journal Article] Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel2016
- Author(s)
  Seino M, Okada M, Sakaki H, Takeda H, Watarai H, Suzuki S, Seino S, Kuramoto K, Ohta T, Nagase S, Kurachi H, Kitanaka C
- Journal Title
  
  Oncology Reports
  
  Volume: 35 Issue: 1 Pages: 593-601
- DOI
  10.3892/or.2015.4377
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20125, KAKENHI-PROJECT-26830065, KAKENHI-PROJECT-15K18437, KAKENHI-PROJECT-16K18410
[Journal Article] The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo.2016
- Author(s)
  Okada M, Kuramoto K, Takeda H, Watarai H, Sakaki H, Seino S, Seino M, Suzuki S, Kitanaka C.
- Journal Title
  
  Oncotarget
  
  Volume: 19 Issue: 19 Pages: 27021-27032
- DOI
  10.18632/oncotarget.8395
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830065, KAKENHI-PROJECT-15H04946, KAKENHI-PROJECT-15K18437, KAKENHI-PROJECT-15K20125, KAKENHI-PROJECT-16K07160, KAKENHI-PROJECT-16K18410
[Journal Article] Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells.2015
- Author(s)
  Shibuya K, Okada M, Suzuki S, Seino M, Seino S, Takeda H, Kitanaka C.
- Journal Title
  
  Oncotarget
  
  Volume: 20 Issue: 2 Pages: 651-661
- DOI
  10.18632/oncotarget.2892
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] Differential contribution of ROS to resveratrol-induced cell death and loss of self-renewal capacity of ovarian cancer stem cells.2015
- Author(s)
  Seino M, Okada M, Shibuya K, Seino S, Suzuki S, Takeda H, Ohta T, Kurachi H, Kitanaka C.
- Journal Title
  
  Anticancer Res
  
  Volume: 1 Pages: 85-96
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells.2015
- Author(s)
  Suzuki S, Okada M, Shibuya K, Seino M, Sato A, Takeda H, Seino S, Yoshioka T, Kitanaka C.
- Journal Title
  
  Oncotarget
  
  Volume: 1 Issue: 1 Pages: 458-470
- DOI
  10.18632/oncotarget.2693
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] GSKJ4, A Selective Jumonji H3K27 Demethylase Inhibitor, Effectively Targets Ovarian Cancer Stem Cells.2015
- Author(s)
  Sakaki H, Okada M, Kuramoto K, Takeda H, Watarai H, Suzuki S, Seino S, Seino M, Ohta T, Nagase S, Kurachi H, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 12 Pages: 6607-14
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] Targeting the K-Ras--JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation. Oncotarget.2014
- Author(s)
  Okada M, Shibuya K, Sato A, Seino S, Suzuki S, Seino M, Kitanaka C.
- Journal Title
  
  Oncotarget
  
  Volume: 13 Pages: 5100-5112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] Downregulation of diacylglycerol kinase zeta enhances activation of cytokine-induced NF-kB signaling pathway2014
- Author(s)
  R. Tsuchiya, T. Tanaka, Y. Hozumi, T. Nakano, M. Okada, M. K. Topham, M. Iino, K. Goto
- Journal Title
  
  BBA Molecular Cell Research
  
  Volume: 1853 Issue: 2 Pages: 361-369
- DOI
  10.1016/j.bbamcr.2014.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460265, KAKENHI-PROJECT-26460266, KAKENHI-PROJECT-26830065
[Journal Article] Role of the N-terminal hydrophobic residues of DGKε in targeting the endoplasmic reticulum.2014
- Author(s)
  Matsui H, Hozumi Y, Tanaka T, Okada M, Nakano T, Suzuki Y, Iseki K, Kakehata S, Topham MK, Goto K.
- Journal Title
  
  Biochim Biophys Acta Molecular and Cell Biology of Lipids
  
  Volume: 1842 Issue: 10 Pages: 1440-1450
- DOI
  10.1016/j.bbalip.2014.07.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390044, KAKENHI-PROJECT-24592729, KAKENHI-PROJECT-26460265, KAKENHI-PROJECT-26460266, KAKENHI-PROJECT-26830065
[Journal Article] Requirement of JNK signaling for self-renewal and tumor-initiating capacity of ovarian cancer stem cells.2014
- Author(s)
  Seino M, Okada M, Shibuya K, Seino S, Suzuki S, Ohta T, Kurachi H, Kitanaka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 9 Pages: 4723-4731
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26830065
[Journal Article] Cellular expression and localization of DGKζ-interacting NAP1-like proteins in the brain and functional implications under hypoxic stress.2014
- Author(s)
  Takahashi N, Hozumi Y, Tanaka T, Okada M, Iseki K, Hayasaka K, Goto K.
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 142 Issue: 5 Pages: 461-471
- DOI
  10.1007/s00418-014-1226-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390044, KAKENHI-PROJECT-26460266, KAKENHI-PROJECT-26670782, KAKENHI-PROJECT-26830065
[Journal Article] Targeting the K-Ras-JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation.2014
- Author(s)
  Okada M, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 5100-5112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670635
[Journal Article] DGKζ is degraded through the cytoplasmic ubiquitin-proteasome system under excitotoxic conditions, which causes neuronal apoptosis because of aberrant cell cycle reentry2012
- Author(s)
  Okada M, Hozumi Y, Tanaka T, Suzuki Y, Yanagida M, Araki Y, Evangelisti C, Yagisawa H, Topham MK, Martelli AM, Goto K.
- Journal Title
  
  Cell Signal
  
  Volume: 24 Issue: 8 Pages: 1573-82
- DOI
  10.1016/j.cellsig.2012.03.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390050, KAKENHI-PROJECT-22501016, KAKENHI-PROJECT-22659325, KAKENHI-PROJECT-22791745, KAKENHI-PROJECT-24390044
[Journal Article] NMDA receptor-mediated Ca(2+) influx triggers nucleocytoplasmic translocation of diacylglycerol kinase ζ under oxygen-glucose deprivation conditions, an in vitro model of ischemia, in rat hippocampal slices2012
- Author(s)
  Suzuki Y, Yamazaki Y, Hozumi Y, Okada M, Tanaka T, Iseki K, Ohta N, Aoyagi M, Fujii S, Goto K.
- Journal Title
  
  Histochem CellBiol
  
  Volume: 137 Issue: 4 Pages: 499-511
- DOI
  10.1007/s00418-011-0907-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390050, KAKENHI-PROJECT-21592302, KAKENHI-PROJECT-22500352, KAKENHI-PROJECT-22590235, KAKENHI-PROJECT-22659325, KAKENHI-PROJECT-22791745, KAKENHI-PROJECT-24500434, KAKENHI-PROJECT-24592729
[Journal Article] DGKzeta is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway2012
- Author(s)
  Okada, M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 420 Issue: 2 Pages: 479-84
- DOI
  10.1016/j.bbrc.2012.03.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-20390050, KAKENHI-PROJECT-22501016, KAKENHI-PROJECT-22659325, KAKENHI-PROJECT-22791745, KAKENHI-PROJECT-24592323
[Journal Article] NAP Interaction of nucleosome assembly proteins abolishes nuclear localization of DGKζ by attenuating its association with importins2011
- Author(s)
  Okada M, Hozumi Y, Ichimura T, Tanaka T, Hasegawa H, Yamamoto M, Takahashi N, Iseki K, Yagisawa H, Shinkawa T, Isobe T, Goto K.
- Journal Title
  
  Exp Cell Res
  
  Volume: 317 Issue: 20 Pages: 2853-63
- DOI
  10.1016/j.yexcr.2011.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390050, KAKENHI-PROJECT-21570213, KAKENHI-PROJECT-22501016, KAKENHI-PROJECT-22659325, KAKENHI-PROJECT-22791745
[Journal Article] Calcium fluxes cause nuclear shrinkage and the translocation of phospholipase C-delta1 into the nucleus2010
- Author(s)
  Okada M, Taguchi K, Maekawa S, Fukami K, Yagisawa H
- Journal Title
  
  Neurosci Lett. 472
  
  Pages: 188-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Calcium fluxes cause nuclear shrinkage and the translocation of phospholipase C-deltal into the nucleus.2010
- Author(s)
  Okada M, et al
- Journal Title
  
  Neurosci Lett. 472
  
  Pages: 188-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Calcium fluxes cause nuclear shrinkage and the translocation of phospholipase C-deltal into the nucleus.2010
- Author(s)
  Okada M, et al(第一著者)
- Journal Title
  
  Neurosci Lett.
  
  Volume: 472 Pages: 188-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791745
[Journal Article] Influence of membrane curvature on the structure of the membrane-associated pleckstrin homology domain of phospholipase C-delta12009
- Author(s)
  Uekama N, Aoki T, Maruoka T, Kurisu S, Hatakeyama A, Yamaguchi S, Okada M, Yagisawa H, Nishimura K, Tuzi S
- Journal Title
  
  Biochim Biophys Acta. 12
  
  Pages: 2575-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Nuclear phosphoinositide signaling regulates messenger RNA export2009
- Author(s)
  Okada M, et.al.
- Journal Title
  
  RNA Biology Jan-Mar ; 6(1)
  
  Pages: 12-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor2009
- Author(s)
  Liu Z, Oh SM, Okada M, Liu X, Cheng D, Peng J, Brat DJ, Sun SY, Zhou W, Gu W, Ye K.
- Journal Title
  
  Mol Biol Cell. 20
  
  Pages: 757-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Akt phosphorylation of merlin enhances its binding to phosphatidylinositols and inhibits the tumor-suppressive activities of Merlin2009
- Author(s)
  Okada M, Wang Y, Jang SW, Tang X, Neri LM, Ye K
- Journal Title
  
  Cancer Res. 69
  
  Pages: 4043-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Akt Phosphorylation of Merlin Enhances Its Binding to Phosphatidylinositols and Inhibits the Tumor-Suppressive Activities of Merlin2009
- Author(s)
  Okada M, et.al.
- Journal Title
  
  Cancer Research (Epub ahead of print)
  
  Pages: 19351837-19351837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity2009
- Author(s)
  Oh SM, Liu Z, Okada M, Jang SW, Liu X, Chan CB, Luo H, Ye K
- Journal Title
  
  Oncogene 29
  
  Pages: 1017-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Nuclear phosphoinositide signaling regulates messenger RNA export2009
- Author(s)
  Okada M, Ye K
- Journal Title
  
  RNA Biol. 6
  
  Pages: 12-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890025
[Journal Article] Ca^<2+>-dependent nuclear accumulation of phospholipase C-d12008
- Author(s)
  Yagisawa, H., Okada, M.
- Journal Title
  
  Neurosci.Res. 61
- Data Source
  KAKENHI-PROJECT-20890025
[Presentation] Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1- JNK axis2021
- Author(s)
  Masashi Okada, Shuhei Suzuki, Tomomi Sanomachi, Keita Togashi, Shizuka Seino, Atsushi Sato, Masahiro Yamamoto, and Chifumi Kitanaka
- Organizer
  第94回　生化学大会
- Data Source
  KAKENHI-PROJECT-20K07631
[Presentation] がん幹細胞におけるJNKの役割2019
- Author(s)
  岡田　雅司、北中　千史
- Organizer
  第92回生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07160
[Presentation] The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo2017
- Author(s)
  Masashi Okada, Shuhei Suzuki, Manabu Seino, Hiroyuki Takeda and Chifumi Kitanaka
- Organizer
  日本癌学会年会
- Data Source
  KAKENHI-PROJECT-16K07160
[Presentation] がん幹細胞におけるJNK経路の機能解析2017
- Author(s)
  岡田　雅司、鈴木　修平、倉元　謙太、武田　弘幸、清野　静香、北中　千史
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K07160
[Presentation] グルコース代謝の抑制はがん幹細胞の幹細胞性維持および腫瘍創始能を抑制する.2016
- Author(s)
  2) 岡田雅司, 北中千史
- Organizer
  第59回放射線影響学会
- Place of Presentation
  JMSアステールプラザ（広島）
- Invited
- Data Source
  KAKENHI-PROJECT-15K15522
[Presentation] 促進性グルコース輸送体GLUT1阻害は癌幹細胞の自己複製能と腫瘍形成能を抑制する.2016
- Author(s)
  岡田雅司, 鈴木修平, 清野学, 武田弘幸, 北中千史
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-15K15522
[Presentation] グルコース代謝の抑制はがん幹細胞の幹細胞性維持および腫瘍創始能を抑制する2016
- Author(s)
  岡田雅司, 北中千史
- Organizer
  放射線影響学会
- Place of Presentation
  JMSアステールプラザ（広島市）
- Year and Date
  2016-10-26
- Invited
- Data Source
  KAKENHI-PROJECT-16K07160
[Presentation] Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells2016
- Author(s)
  Masashi Okada, Shuhei Suzuki, Manabu Seino, Hiroyuki Takeda, and Chifumi Kitanaka
- Organizer
  日本癌学会　年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K07160
[Presentation] Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation2015
- Author(s)
  Masashi Okada, Keita Shibuya, Atsushi Sato, Shuhei Suzuki, Manabu Seino and Chifumi Kitanaka
- Organizer
  BMB2015
- Place of Presentation
  神戸・ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830065
[Presentation] Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation2015
- Author(s)
  Masashi Okada, Keita Shibuya, Atsushi Sato, Shuhei Suzuki, Manabu Seino, Chifumi Kitanaka
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋・名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26830065
[Presentation] DGKζ is a suppressor of excitotoxic neuronal cell death2011
- Author(s)
  Masashi Okada, Kaoru Goto
- Organizer
  JBSバイオフロンティア国際シンポジウム九州大学創立百周年記念
- Place of Presentation
  Hotel Luigans-Spa and Resort-福岡市
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22791745
[Presentation] DGKζ is a suppressor of excitotoxic neuronal cell death2011
- Author(s)
  Masashi Okada, Kaoru Goto
- Organizer
  分子生物学会年会
- Place of Presentation
  パシフィコ横浜横浜市
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22791745
[Presentation] DGKζis a suppressor of excitotoxic neuronal cell death2011
- Author(s)
  Masashi Okada, Kaoru Goto
- Organizer
  JBS バイオフロンティア国際シンポジウム九州大学創立百周年記念
- Place of Presentation
  福岡、Hotel Luigans-Spa and Resort
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22791745
[Presentation] DGK ζ is a suppressor of excitotoxic neuronal cell death2011
- Author(s)
  Masashi Okada, Kaoru Goto
- Organizer
  分子生物学会年会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22791745
[Presentation] Nuclear assemblyproteinはDGKζの細胞内局在を制御する2010
- Author(s)
  岡田雅司、後藤薫
- Organizer
  第115回日本解剖学会総会
- Place of Presentation
  岩手医科大学、盛岡
- Data Source
  KAKENHI-PROJECT-20390050
[Presentation] Nuclear assembly protein はDGKζの細胞内局在を制御する.2010
- Author(s)
  岡田雅司、後藤薫
- Organizer
  第115回日本解剖学会総会
- Place of Presentation
  盛岡
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20390050
[Presentation] Nucleaosome assembly protein はDGKz の核-細胞質間輸送を制御する2010
- Author(s)
  岡田雅司、後藤薫
- Organizer
  日本分子生物学会年会、日本生化学大会合同大会
- Place of Presentation
  神戸、神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22791745
[Presentation] Nucleaosome assembly proteinはDGKzの核-細胞質間輸送を制御する2010
- Author(s)
  岡田雅司、後藤薫
- Organizer
  日本分子生物学会年会、日本生化学大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22791745
[Presentation] Nuclear assembly protein はDGKζの細胞内局在を制御する2010
- Author(s)
  岡田雅司, 後藤薫
- Organizer
  日本解剖学会全国学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20890025
[Presentation] Nuclear assembly proteinはDGKζに結合しその細胞内局在を制御する2010
- Author(s)
  岡田雅司
- Organizer
  日本解剖学会
- Place of Presentation
  岩手医科大学
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20890025
[Presentation] DGKζ結合タンパクの探索とその性状解析2009
- Author(s)
  岡田雅司, 後藤薫
- Organizer
  日本解剖学会東北北海道支部地方会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20890025
[Presentation] 細胞質局在型ジアシルグリゼロールキナーゼζはp53の発現を抑制する2009
- Author(s)
  田中俊昭、岡田雅司、後藤薫
- Organizer
  第114回日本解剖学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20390050
[Presentation] Cytoplasmic lipid kinase suppresses p53 stability.2009
- Author(s)
  Toshiaki Tanaka, Masashi Okada, Kaoru Goto.
- Organizer
  39th Annual Meeting of Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20390050
[Presentation] Cytoplasmic lipid kinase suppresses p53 stability2009
- Author(s)
  Toshiaki Tanaka, Masashi Okada, Kaoru Goto
- Organizer
  39th Annual Meeting of Neuroscience, Convention Center
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20390050
[Presentation] JNK contributes to temozolomide resistance of glioma stem cells via regulation of MGMT expression
- Author(s)
  Masashi Okada, Atsushi Sato, Keita Shibuya, Shuhei Suzuki, Manabu Seino, Yoshitaka Narita, Soichiro Shibui, Takamasa Kayama, Chifumi Kitanaka
- Organizer
  日本癌学会　年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26830065

1. KITANAKA Chifumi (70260320)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. GOTO Kaoru (30234975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. ISEKI Ken (70332921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. HOZUMI Yasukazu (00372334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. TANAKA Toshiaki (70536987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 冨樫敬太

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 鈴木修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
8. 佐野町友美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中野知之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 清野学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okada Masashi 岡田 雅司

OKADA MASASHI 岡田 雅司

OKADA Masashi 岡田 雅司

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がん幹細胞のアキレス腱としてのエピジェネティック修飾を標的とする新規治療法の確立Principal Investigator

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Development of novel anti-cancer stem cell therapeutic strategies targeting oxidative phosphorylationPrincipal Investigator

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Trial to establish new cancer stem cell targeting therapy utilizing drug repositioningPrincipal Investigator

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Taking advantage of a pitfall in glioma cancer stem cell epigenetics to develop novel therapies directed to cancer stem cells

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An attempt to answer the cardinal question --- why do cancer cells have such a sweet tooth? --- through glioma stem cell research

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The impact of JNK activity on the cancer stem cellsPrincipal Investigator

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An attempt to create an animal model for glioblastoma cure via proving the hypothesis that glucose metabolism serves as a rheostat to determine the cell fate of cancer stem cells

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Functional analysis of phospholipid-metabolizing enzyme signal transduction during early phase of cell death after ischemiaPrincipal Investigator

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Functional role of lipid second messenger metabolizing enzyme in cell cycle and stress response

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Functional analysis of phospholipid metabolizing enzymes during cell death after ischemiaPrincipal Investigator

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[Journal Article] Domatinostat Targets the FOXM1?Survivin Axis to Reduce the Viability of Ovarian Cancer Cells Alone and in Combination with Chemotherapeutic Agents2023

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[Journal Article] Givinostat Inhibition of Sp1-dependent MGMT Expression Sensitizes Glioma Stem Cells to Temozolomide.2023

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[Journal Article] The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo2023

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Okada Masashi 岡田雅司

OKADA MASASHI 岡田雅司

OKADA Masashi 岡田雅司