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Higashi Tomohito  東 智仁

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… Alternative Names

東 智仁  ヒガシ トモヒト

HIGASHI Tomohito  東 智仁

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Researcher Number 70515072
Other IDs
Affiliation (Current) 2020: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2019: 福島県立医科大学, 医学部, 准教授
2018: 福島県立医科大学, 医学部, 講師
2011: Kobe University, 医学(系)研究科(研究院), 研究員
2010: Kobe University, 大学院・医学研究科, グローバルCOE研究員
2009 – 2010: Kobe University, 医学研究科, グローバルCOE研究員
Review Section/Research Field
Principal Investigator
Cell biology / Basic Section 44010:Cell biology-related
Except Principal Investigator
Basic Section 49020:Human pathology-related
Keywords
Principal Investigator
細胞間接着 / アクチン細胞骨格 / 上皮細胞 / タイトジャンクション / Rho低分子量Gタンパク質 / ArhGEF11 / RhoGEF / 裏打ちアクチン / RhoA / フォルミン … More / アフリカツメガエル / アドレヘンスジャンクション / Rho / アドヘレンスジャンクション / 分裂収縮環 / ライブイメージング … More
Except Principal Investigator
JAMファミリー / CLMP / 蠕動 / 腸上皮幹細胞 / タイト結合 / クローディン / ゲノム編集 / 腸管オルガノイド / 病理学 Less
  • Research Projects

    (4 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (2 People)
  •  カエル初期胚上皮細胞を用いた収縮環と細胞間接着のアクチン細胞骨格制御機構の解明Principal InvestigatorOngoing

    • Principal Investigator
      東 智仁
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Fukushima Medical University
  •  タイト結合分子による腸上皮幹細胞の新規運命決定機構Ongoing

    • Principal Investigator
      田中 瑞子
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Fukushima Medical University
  •  密着結合のバリア機能維持機構の解明Principal Investigator

    • Principal Investigator
      東 智仁
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Kobe University
  •  Analysis of molecular mechanisms of the formation of the intercellular junction-underlying actin bundle using semi-intact epithelium.Principal Investigator

    • Principal Investigator
      HIGASHI Tomohito
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Kobe University

All 2020 2019 2010 2009

All Journal Article Presentation

  • [Journal Article] Molecular organization, regulation and function of tricellular junctions2020

    • Author(s)
      Tomohito Higashi, Hideki Chiba
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Biomembranes

      Volume: 1862 Pages: 183143-183143

    • DOI

      10.1016/j.bbamem.2019.183143

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06223, KAKENHI-PROJECT-17K08699
  • [Journal Article] Comprehensive analysis of formin localization in Xenopus epithelial cells.2019

    • Author(s)
      Tomohito Higashi, Rachel E. Stepheson, Ann L. Miller
    • Journal Title

      Molecular Biology of the Cell

      Volume: 30 Pages: 82-95

    • DOI

      10.1091/mbc.e18-02-0133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06223
  • [Journal Article] Horiuchi H Flightless-I (Fli-I) regulates the actin assembly of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperationwith active Rho GTPases.2010

    • Author(s)
      Higashi T, Ikeda T, Murakami T, Shirakawa R, Kawato M, Okawa K, Furuse M, Kimura T, Kita T.
    • Journal Title

      J Biol Chem 285巻

      Pages: 16231-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770212
  • [Presentation] Flightless-I (Fli-I) regulates the actin assembly activity of Diaphanous-related formins (DRFs) Daaml and mDial in cooperation with active Rho.2010

    • Author(s)
      東智仁
    • Organizer
      アメリカ細胞生物学会
    • Place of Presentation
      ペンシルベニア会議場(米国・フィラデルフィア)
    • Year and Date
      2010-12-13
    • Data Source
      KAKENHI-PROJECT-21770212
  • [Presentation] PDZ-RhoGEFは細胞間接着部位に局在し上皮細胞のアピカル面張力を制御する2010

    • Author(s)
      東智仁
    • Organizer
      日本細胞生物学会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-21770212
  • [Presentation] ArhGEF11 localizes at intercellular junction of epithelial cells and regulates the actin cytoskeletal organization.2009

    • Author(s)
      東智仁
    • Organizer
      日本分子生物学会第32回年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-21770212
  • 1.  田中 瑞子 (40583638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  千葉 英樹 (00295346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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