Higashi Tomohito 東智仁

… Alternative Names

Researcher Number	70515072
Other IDs
Affiliation (Current)	2021: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021: 福島県立医科大学, 医学部, 准教授 2019: 福島県立医科大学, 医学部, 准教授 2018: 福島県立医科大学, 医学部, 講師 2011: Kobe University, 医学(系)研究科(研究院), 研究員 2010: Kobe University, 大学院・医学研究科, グローバルCOE研究員 2009 – 2010: Kobe University, 医学研究科, グローバルCOE研究員
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 44010:Cell biology-related Except Principal Investigator Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 細胞間接着 / アクチン細胞骨格 / 上皮細胞 / タイトジャンクション / Rho低分子量Gタンパク質 / ArhGEF11 / RhoGEF / 裏打ちアクチン / RhoA / フォルミン … More Except Principal Investigator JAMファミリー / CLMP / 蠕動 / 腸上皮幹細胞 / タイト結合 / クローディン / ゲノム編集 / 腸管オルガノイド / 病理学 Less

プロテアーゼによる密着結合の恒常性維持機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  東智仁
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Fukushima Medical University
カエル初期胚上皮細胞を用いた収縮環と細胞間接着のアクチン細胞骨格制御機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  東智仁
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Fukushima Medical University
タイト結合分子による腸上皮幹細胞の新規運命決定機構Ongoing
- Principal Investigator
  
  田中瑞子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Fukushima Medical University
密着結合のバリア機能維持機構の解明Principal Investigator
- Principal Investigator
  
  東智仁
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University
Analysis of molecular mechanisms of the formation of the intercellular junction-underlying actin bundle using semi-intact epithelium.Principal Investigator
- Principal Investigator
  
  HIGASHI Tomohito
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University

All 2020 2019 2010 2009

All Journal Article Presentation

[Journal Article] Molecular organization, regulation and function of tricellular junctions2020
- Author(s)
  Tomohito Higashi, Hideki Chiba
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1862 Pages: 183143-183143
- DOI
  10.1016/j.bbamem.2019.183143
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06223, KAKENHI-PROJECT-17K08699
[Journal Article] Comprehensive analysis of formin localization in Xenopus epithelial cells.2019
- Author(s)
  Tomohito Higashi, Rachel E. Stepheson, Ann L. Miller
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 30 Pages: 82-95
- DOI
  10.1091/mbc.e18-02-0133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06223
[Journal Article] Horiuchi H Flightless-I (Fli-I) regulates the actin assembly of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperationwith active Rho GTPases.2010
- Author(s)
  Higashi T, Ikeda T, Murakami T, Shirakawa R, Kawato M, Okawa K, Furuse M, Kimura T, Kita T.
- Journal Title
  
  J Biol Chem 285巻
  
  Pages: 16231-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770212
[Presentation] Flightless-I (Fli-I) regulates the actin assembly activity of Diaphanous-related formins (DRFs) Daaml and mDial in cooperation with active Rho.2010
- Author(s)
  東智仁
- Organizer
  アメリカ細胞生物学会
- Place of Presentation
  ペンシルベニア会議場(米国・フィラデルフィア)
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21770212
[Presentation] PDZ-RhoGEFは細胞間接着部位に局在し上皮細胞のアピカル面張力を制御する2010
- Author(s)
  東智仁
- Organizer
  日本細胞生物学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21770212
[Presentation] ArhGEF11 localizes at intercellular junction of epithelial cells and regulates the actin cytoskeletal organization.2009
- Author(s)
  東智仁
- Organizer
  日本分子生物学会第32回年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21770212

1. 田中瑞子 (40583638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 千葉英樹 (00295346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Higashi Tomohito 東 智仁

東 智仁 ヒガシ トモヒト

HIGASHI Tomohito 東 智仁

Research Projects

Research Products

Co-Researchers

プロテアーゼによる密着結合の恒常性維持機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

カエル初期胚上皮細胞を用いた収縮環と細胞間接着のアクチン細胞骨格制御機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タイト結合分子による腸上皮幹細胞の新規運命決定機構Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

密着結合のバリア機能維持機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanisms of the formation of the intercellular junction-underlying actin bundle using semi-intact epithelium.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Molecular organization, regulation and function of tricellular junctions2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive analysis of formin localization in Xenopus epithelial cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Horiuchi H Flightless-I (Fli-I) regulates the actin assembly of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperationwith active Rho GTPases.2010

Author(s)

Journal Title

Data Source

[Presentation] Flightless-I (Fli-I) regulates the actin assembly activity of Diaphanous-related formins (DRFs) Daaml and mDial in cooperation with active Rho.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PDZ-RhoGEFは細胞間接着部位に局在し上皮細胞のアピカル面張力を制御する2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ArhGEF11 localizes at intercellular junction of epithelial cells and regulates the actin cytoskeletal organization.2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Higashi Tomohito 東智仁

東智仁ヒガシトモヒト

HIGASHI Tomohito 東智仁