MIZUGISHI KIYOMI 水岸貴代美

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MIZUGISHI Kiyomi 水岸貴代美

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Researcher Number	70518448
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2023: 京都大学, 医学研究科, 研究員 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 研究員 2011: 京都大学, 医学研究科, 研究員 2009 – 2010: Musashino University, 薬学研究所, 講師
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator スフィンゴ脂質 / 胎児医学 / 妊娠 / 不育症 / 自然免疫 / シトルリン化 / 好中球細胞外トラップ / ケモカイン / 胎児発育

正常妊娠維持および不育症におけるスフィンゴ脂質代謝の役割の解明Principal Investigator
- Principal Investigator
  
  水岸貴代美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto University
Elucidation of the role of sphingolipid metabolism in normal pregnancy and pregnancy lossPrincipal Investigator
- Principal Investigator
  
  Mizugishi Kiyomi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto University
Elucidation of the molecular mechanism and development of therapeutic strategies for the sphingolipid-mediated pregnancy lossPrincipal Investigator
- Principal Investigator
  
  Mizugishi Kiyomi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyoto University
Elucidation of the molecular mechanism and development of therapeutic strategies for the sphingolipid-mediated pregnancy lossPrincipal Investigator
- Principal Investigator
  
  Mizugishi Kiyomi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyoto University
Sphingolipid Metabolism in Pregnancy and Fetal DevelopmentPrincipal Investigator
- Principal Investigator
  
  MIZUGISHI Kiyomi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyoto University
  Musashino University

All 2018 2017 2015 2014 2013 2010 Other

All Journal Article Presentation

[Journal Article] Familial Mediterranean Fever Mutations in a Patient with Periodic Episodes of Systemic Pain Deriving from Cancer Bone Metastases2018
- Author(s)
  Yamashita Kouhei、Mizugishi Kiyomi、Takaori-Kondo Akifumi
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 19 Pages: 2901-2904
- DOI
  10.2169/internalmedicine.0431-17
- NAID
  130007493108
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09711
[Journal Article] Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.2017
- Author(s)
  Mizugishi K and Yamashita K.
- Journal Title
  
  FASEB J.
  
  Volume: 31 Issue: 12 Pages: 5577-5591
- DOI
  10.1096/fj.201700399rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-15K09711
[Journal Article] Risk factors for late-onset neutropenia after rituximab treatment of B-cell lymphoma.2015
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Nishikori M, Hishizawa M, Kondo T, Kitano T, Kawabata H, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Hematology
  
  Volume: 20 Issue: 4 Pages: 196-202
- DOI
  10.1179/1607845414y.0000000188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09711, KAKENHI-PROJECT-24591600
[Journal Article] Phagocytosis by human monocytes is required for the secretion of presepsin.2015
- Author(s)
  Arai Y, Mizugishi K, Nonomura K, Naito K, Takaori-Kondo A, Yamashita K.
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 21 Issue: 8 Pages: 564-569
- DOI
  10.1016/j.jiac.2015.04.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-15K09711, KAKENHI-PROJECT-24591600
[Journal Article] 自己免疫性膵炎の診断について　診断基準の変遷と診断の現状2015
- Author(s)
  内田一茂, 岡崎和一
- Journal Title
  
  日本臨床免疫学会雑誌
  
  Volume: 38 Issue: 7 Pages: 127-134
- DOI
  10.4049/jimmunol.1500971
- NAID
  130005089220
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09052, KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-15K09501, KAKENHI-PROJECT-15K09711, KAKENHI-PROJECT-26460979, KAKENHI-PROJECT-15K15370, KAKENHI-PROJECT-24591600, KAKENHI-PROJECT-25293172
[Journal Article] Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy.2015
- Author(s)
  Mizugishi K, Inoue T, Hatayama H, Bielawski J, Pierce JS, Sato Y, Takaori-Kondo A, Konishi I, Yamashita K
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 290 Issue: 4 Pages: 2053-2068
- DOI
  10.1074/jbc.m114.628867
- NAID
  40020640385
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591600, KAKENHI-PROJECT-24592470
[Journal Article] Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.2014
- Author(s)
  Arai Y, Nishinaka Y, Arai T, Morita M, Mizugishi K, Adachi S, Takaori-Kondo A, Watanabe T, Yamashita K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Issue: 2 Pages: 556-561
- DOI
  10.1016/j.bbrc.2013.12.007
- NAID
  40021104154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] Risk factors for hypogammaglobulinemia after allo-SCT.2014
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Kondo T, Kitano T, Hishizawa M, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 49 Issue: 6 Pages: 859-861
- DOI
  10.1038/bmt.2014.28
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591600
[Journal Article] The implication of myelodysplastic syndrome-associated chromosomal abnormalities in the development of graft-versus-host disease.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Takaori-Kondo A, Chiba T, Watanabe T.
- Journal Title
  
  Eur J Haematol
  
  Volume: 90 Issue: 6 Pages: 525-530
- DOI
  10.1111/ejh.12100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24591600
[Journal Article] Familial Mediterranean fever mutations in a patient with recurrent episodes of acute respiratory distress syndrome.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Watanabe T, Kondo T, Kitano T, Kawabata H, Kadowaki N, Takaori-Kondo A.
- Journal Title
  
  Clin Immunol
  
  Volume: 147 Issue: 1 Pages: 58-60
- DOI
  10.1016/j.clim.2013.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] Enhanced generation of reactive oxygen species by interferon-gamma may have contributed to successful treatment of invasive pulmonary aspergillosis in a patient with chronic granulomatous disease.2013
- Author(s)
  Yamashita K, Miyoshi T, Arai Y, Mizugishi K, Takaori-Kondo A, Ueyama T.
- Journal Title
  
  Int J Hematol
  
  Volume: 97 Issue: 4 Pages: 505-510
- DOI
  10.1007/s12185-013-1315-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] Serum neutrophil extracellular traps levels predict thrombotic microangiopathy after allogeneic stem cell transplantation.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Watanabe T, Sakamoto S, Kitano T, Kondo T, Kawabata H, Kadowaki N, Takaori-Kondo A.
- Journal Title
  
  Biol Blood Marrow Transpl
  
  Volume: 19 Issue: 12 Pages: 1683-1689
- DOI
  10.1016/j.bbmt.2013.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species2010
- Author(s)
  Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, Banno Y, Sasaki M, Ichi I, Okamura M, Sugimoto N, Mizugishi K, Nakanuma Y, Ishii I, Takamura M, Kaneko S, Kojo S, Satouchi K, Mitumori K, Chun J, Takuwa Y
- Journal Title
  
  Cardiovasc Res
  
  Volume: 85(3) Issue: 3 Pages: 484-493
- DOI
  10.1093/cvr/cvp312
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-21591414, KAKENHI-PROJECT-22590284
[Journal Article] The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis.2010
- Author(s)
  Miyoshi Takashi, Yamashita Kouhei, Arai Toshiyuki, Yamamoto Kokichi, Mizugishi Kiyomi, Uchiyama T akashi
- Journal Title
  
  Immunology
  
  Volume: 131 Issue: 3 Pages: 331-339
- DOI
  10.1111/j.1365-2567.2010.03303.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591414
[Presentation] Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy.2015
- Author(s)
  水岸貴代美、山下浩平
- Organizer
  Experimental Biology 2015
- Place of Presentation
  ボストン
- Year and Date
  2015-03-31
- Data Source
  KAKENHI-PROJECT-24591600
[Presentation] スフィンゴ脂質代謝異常による胎児発育障害のメカニズムの解明
- Author(s)
  水岸　貴代美
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-24591600
[Presentation] 正常妊娠および不育症におけるスフィンゴ脂質代謝の意義
- Author(s)
  水岸　貴代美
- Organizer
  第48回日本周産期・新生児医学会学術集会
- Place of Presentation
  大宮ソニックシティ（大宮）
- Data Source
  KAKENHI-PROJECT-24591600

1. YAMASHITA Kouhei

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
2. UCHIDA Kazushige

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 多久和典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 吉岡和晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 多久和陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUGISHI KIYOMI 水岸 貴代美

MIZUGISHI Kiyomi 水岸 貴代美

Research Projects

Research Products

Co-Researchers

正常妊娠維持および不育症におけるスフィンゴ脂質代謝の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the role of sphingolipid metabolism in normal pregnancy and pregnancy lossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism and development of therapeutic strategies for the sphingolipid-mediated pregnancy lossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular mechanism and development of therapeutic strategies for the sphingolipid-mediated pregnancy lossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sphingolipid Metabolism in Pregnancy and Fetal DevelopmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Familial Mediterranean Fever Mutations in a Patient with Periodic Episodes of Systemic Pain Deriving from Cancer Bone Metastases2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Risk factors for late-onset neutropenia after rituximab treatment of B-cell lymphoma.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phagocytosis by human monocytes is required for the secretion of presepsin.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 自己免疫性膵炎の診断について 診断基準の変遷と診断の現状2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Risk factors for hypogammaglobulinemia after allo-SCT.2014

Author(s)

Journal Title

MIZUGISHI KIYOMI 水岸貴代美

MIZUGISHI Kiyomi 水岸貴代美

[Journal Article] 自己免疫性膵炎の診断について　診断基準の変遷と診断の現状2015