Yamazaki Hiroyuki 山崎寛之

… Alternative Names

YAMAZAKI Hiroyuki 山崎寛之

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Researcher Number	70525344
Other IDs	https://orcid.org/0000-0002-1540-7255
Affiliation (Current)	2025: 東北医科薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東北医科薬科大学, 薬学部, 准教授 2016 – 2019: 東北医科薬科大学, 薬学部, 講師 2013 – 2015: 東北薬科大学, 薬学部, 助教 2011: 東北薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Natural medicines / Biomolecular chemistry Except Principal Investigator Chemical biology
Keywords	Principal Investigator 二次代謝産物 / 休眠生合成遺伝子 / 特殊培養条件 / 生物活性物質 / 誘導生産 / 新規活性物質 / 海洋糸状菌 / 特殊微生物 / 植物内生糸状菌 / 海洋微生物 … More / 新規生物活性物質 / ケミカルエピジェネティクス / 培養条件 / 抗真菌活性 / 生物活性 / 培養条件検討 / 希少海洋微生物 / 海洋天然物化学 / 共培養 / 海洋放線菌 / 放線菌 / 糸状菌 … More Except Principal Investigator α-カルボリン / NF-κB / TNF-α / 生物活性発現機構 / 抗炎症活性 / 抗癌活性 / アルカロイド / ホヤ Less

特殊微生物と特殊培養法の融合による新規二次代謝産物の生産Principal Investigator
- Principal Investigator
  
  山崎寛之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
特殊微生物を活用した培養法の確立と新規二次代謝産物の創出Principal Investigator
- Principal Investigator
  
  山崎寛之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Study on various culture investigations for rare marine-derived microorganismsPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tohoku Medical and Pharmaceutical University
Development of induced production method for dormant fungal secondary metabolites with a combination of chemical epigenetics and several culture conditionsPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Hiroyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Natural medicines
- Research Institution
  Tohoku Medical and Pharmaceutical University
Development of induced production method for dormant fungal secondary biogenesis by modulating new epigenetic targetsPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Natural medicines
- Research Institution
  Tohoku Pharmaceutical University
Studies on the mechanisms of anticancer and anti-inflammatory activities of alkaloids from ascidians
- Principal Investigator
  
  NAMIKOSHI Michio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Tohoku Pharmaceutical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012 2011

All Journal Article Presentation

[Journal Article] Evaluation on bioactivity of ascidian collected in North Sulawesi as seeds of marine-derived drugs2023
- Author(s)
  Defny S. Wewengkang, Henki Rotinsulu, Deiske A. Sumilat, Hiroyuki Yamazaki, Syu-ichi Kanno, Michio Namikoshi
- Journal Title
  
  AIP Conf. Proc.
  
  Volume: 2694 Pages: 060012-060012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06631
[Journal Article] Anti-mycobacterial activity of polycarpine and polycarpaurine A from an Indonesia marine ascidian Polycarpa sp.2023
- Author(s)
  Wilmar Maarisit, Sonny D. Untu, Yessi K. Lengkey, Torry C.C. Lomban, Jabes W. Kanter, Hiroyuki Yamazaki, Michio Namikoshi, Fitje Losung, Veibe Warouw, Remy E.P. Mangindaan
- Journal Title
  
  Trop. J. Nat. Prod. Res.
  
  Volume: 7 Pages: 3898-3901
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06631
[Journal Article] Exploration of marine natural resources in Indonesia and development of efficient strategies for the production of microbial halogenated metabolites2022
- Author(s)
  Yamazaki Hiroyuki
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 76 Issue: 1 Pages: 1-19
- DOI
  10.1007/s11418-021-01557-3
- NAID
  40022799474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06631
[Journal Article] New piericidin rhamnosides as potentiators of amphotericin B activity against Candida albicans produced by actinomycete strain TMPU-A02872022
- Author(s)
  Yagi Akiho、Yamaguchi Yuga、Kawasaki Keiko、Usui Eri、Yamazaki Hiroyuki、Uchida Ryuji
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 76 Issue: 2 Pages: 65-74
- DOI
  10.1038/s41429-022-00581-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06631
[Journal Article] Inhibitory effects of sesquiterpene lactones from the Indonesian marine sponge Lamellodysidea cf. herbacea on bone morphogenetic protein-induced osteoblastic differentiation2021
- Author(s)
  Ohte Satoshi、Yamazaki Hiroyuki、Takahashi Ohgi、Rotinsulu Henki、Wewengkang Defny S.、Sumilat Deiske A.、Abdjul Delfly B.、Maarisit Wilmar、Kapojos Magie M.、Zhang Huiping、Hayashi Fumiaki、Namikoshi Michio、Katagiri Takenobu、Tomoda Hiroshi、Uchida Ryuji
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 35 Pages: 127783-127783
- DOI
  10.1016/j.bmcl.2021.127783
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05345, KAKENHI-PROJECT-21K06631
[Journal Article] Three Bioactive Compounds Against Colony Formation of Chinese Hamster V79 Cells from an Indonesian Ascidian Didemnum sp.2021
- Author(s)
  Wewengkang D. S.、Rotinsulu H.、Sumilat D. A.、Oda T.、Yamazaki H.、Ukai K.、Namikoshi M.
- Journal Title
  
  Chemistry of Natural Compounds
  
  Volume: 57 Issue: 3 Pages: 592-593
- DOI
  10.1007/s10600-021-03427-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06631
[Journal Article] Germacrane sesquiterpenes from leaves of Eupatorium chinense inhibit protein tyrosine phosphatase2021
- Author(s)
  Yamazaki Hiroyuki、Tsuge Hayato、Takahashi Ohgi、Uchida Ryuji
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 53 Pages: 128422-128422
- DOI
  10.1016/j.bmcl.2021.128422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06631
[Journal Article] Epipolythiodiketopiperazine and trichothecene derivatives from the NaI-containing fermentation of marine-derived Trichoderma cf. brevicompactum2020
- Author(s)
  Yamazaki Hiroyuki、Takahashi Ohgi、Kirikoshi Ryota、Yagi Akiho、Ogasawara Teruki、Bunya Yuki、Rotinsulu Henki、Uchida Ryuji、Namikoshi Michio
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 73 Issue: 8 Pages: 559-567
- DOI
  10.1038/s41429-020-0314-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Inhibition of interleukin-8 production in interleukin-1 stimulated human monocytic THP-1 cells by N,N didesmethylgrossularine-1 obtained from an Ascidian Polycarpa aurata collected in North Sulawesi2019
- Author(s)
  Sumilat Deiske A.、Oda Taiko、Wewengkang Defny S.、Namikoshi Michio、Yamazaki Hiroyuki
- Journal Title
  
  IOP Conference Series: Materials Science and Engineering
  
  Volume: 567 Issue: 1 Pages: 012021-012021
- DOI
  10.1088/1757-899x/567/1/012021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Inhibition of neutral lipid synthesis by avarols from a marine sponge.2019
- Author(s)
  Ohshiro T, Kobayashi K, Suzuki A, Yamazaki H, Uchida R, Namikoshi M, Tomoda H.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 29 Issue: 16 Pages: 2283-2285
- DOI
  10.1016/j.bmcl.2019.06.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06555, KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Search for Protein Tyrosine Phosphatase 1B Inhibitors from Marine Organisms and Induced Production of New Fungal Metabolites by Modulating Culture Methods2019
- Author(s)
  Yamazaki Hiroyuki
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 5 Pages: 663-672
- DOI
  10.1248/yakushi.18-00221
- NAID
  130007641022
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-05-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Production of an α-pyrone metabolite and microbial transformation of isoflavones by an Indonesian Streptomyces sp.2019
- Author(s)
  Wewengkang Defny S.、Yamazaki Hiroyuki、Takahashi Moe、Togashi Toshiki、Rotinsulu Henki、Sumilat Deiske A.、Namikoshi Michio
- Journal Title
  
  Journal of Asian Natural Products Research
  
  Volume: - Issue: 8 Pages: 1-8
- DOI
  10.1080/10286020.2019.1635588
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] A new protein tyrosine phosphatase 1B inhibitory α-pyrone derivative from the Okinawan plant-associated Aspergillus sp. TMPU16232018
- Author(s)
  Yamazaki Hiroyuki、Takahashi Kenta、Iwakura Natsuki、Abe Tatsuki、Akaishi Masanari、Chiba Satomi、Namikoshi Michio、Uchida Ryuji
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 印刷中 Issue: 8 Pages: 745-748
- DOI
  10.1038/s41429-018-0054-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Anti-mycobacterial haliclonadiamine alkaloids from the Okinawan marine sponge Haliclona sp. collected at Iriomote Island2018
- Author(s)
  Abdjul Delfly B.、Yagi Akiho、Yamazaki Hiroyuki、Kirikoshi Ryota、Takahashi Ohgi、Namikoshi Michio、Uchida Ryuji
- Journal Title
  
  Phytochemistry Letters
  
  Volume: 26 Pages: 130-133
- DOI
  10.1016/j.phytol.2018.05.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173, KAKENHI-PROJECT-16H05095
[Journal Article] Halogenated cladosporols produced by the sodium halide-supplemented fermentation of the plant-associated fungus Cladosporium sp. TMPU16212018
- Author(s)
  Yamazaki Hiroyuki、Yagi Akiho、Akaishi Masanari、Kirikoshi Ryota、Takahashi Ohgi、Abe Tatsuki、Chiba Satomi、Takahashi Kenta、Iwakura Natsuki、Namikoshi Michio、Uchida Ryuji
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 59 Issue: 20 Pages: 1913-1915
- DOI
  10.1016/j.tetlet.2018.03.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Absolute Structures of Wedelolide Derivatives and Structure–Activity Relationships of Protein Tyrosine Phosphatase 1B Inhibitory ent-Kaurene Diterpenes from Aerial Parts of Wedelia spp. Collected in Indonesia and Japan2018
- Author(s)
 Abdjul Delfly Booby、Yamazaki Hiroyuki、Kanno Syu-ichi、Kirikoshi Ryota、Tomizawa Ayako、Takahashi Ohgi、Maarisit Wilmar、Losung Fitje、Rotinsulu Henki、Wewengkang Defny Silvia、Sumilat Deiske Adeliene、Kapojos Magie Melanie、Namikoshi Michio
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 66 Issue: 6 Pages: 682-687
- DOI
 10.1248/cpb.c18-00117
- NAID
 130007382328
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2018-06-01
- Language
 English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp.2018
- Author(s)
  Kapojos MM, Abdjul DB, Yamazaki H, Ohshiro T, Rotinsulu H, Wewengkang DS, Sumilat DA, Tomoda H, Namikoshi M, Uchida R.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 28 Issue: 10 Pages: 1911-1914
- DOI
  10.1016/j.bmcl.2018.03.077
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900, KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Protein tyrosine phosphatase 1B inhibitory components and a new unique N-alkylamide derivative with an endoperoxide bridge from aerial parts of Indonesian Spilanthes paniculata2018
- Author(s)
  Abdjul Delfly B.、Yamazaki Hiroyuki、Maarisit Wilmar、Kirikoshi Ryota、Takahashi Ohgi、Losung Fitje、Kapojos Magie M.、Namikoshi Michio
- Journal Title
  
  Phytochemistry Letters
  
  Volume: 24 Pages: 71-74
- DOI
  10.1016/j.phytol.2018.01.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Bioactivity of extracts from ascidians collected in North Sulawesi as seeds of marine-derived drugs2018
- Author(s)
  Sumilat Deiske A.、Wewengkang Defny S.、Rotinsulu Henki、Yamazaki Hiroyuki、Oda Taiko、Ukai Kazuyo、Namikoshi Michio
- Journal Title
  
  AACL. Bioflux
  
  Volume: 11 Pages: 516-524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Protein tyrosine phosphatase 1B inhibitory polybromobiphenyl ethers and monocyclofarnesol-type sesquiterpenes from the Indonesian marine sponge Lamellodysidea cf. herbacea2018
- Author(s)
  Kapojos Magie M.、Abdjul Delfly B.、Yamazaki Hiroyuki、Kirikoshi Ryota、Takahashi Ohgi、Rotinsulu Henki、Wewengkang Defny S.、Sumilat Deiske A.、Ukai Kazuyo、Namikoshi Michio
- Journal Title
  
  Phytochemistry Letters
  
  Volume: 24 Pages: 10-14
- DOI
  10.1016/j.phytol.2017.11.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Cladosporamide A, a new protein tyrosine phosphatase 1B inhibitor, produced by an Indonesian marine sponge-derived Cladosporium sp.2018
- Author(s)
  Rotinsulu Henki、Yamazaki Hiroyuki、Sugai Shino、Iwakura Natsuki、Wewengkang Defny S.、Sumilat Deiske A.、Namikoshi Michio
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 72 Issue: 3 Pages: 779-783
- DOI
  10.1007/s11418-018-1193-y
- NAID
  40021618028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
[Journal Article] Bioactivity of extracts from ascidians collected in North Sulawesi as seeds of marine-derived drugs2018
- Author(s)
  Sumilat Deiske A.、Wewengkang Defny S.、Rotinsulu Henki、Yamazaki Hiroyuki、Oda Taiko、Ukai Kazuyo、Namikoshi Michio
- Journal Title
  
  AACL. Bioflux
  
  Volume: 11 Pages: 516-524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0173
[Journal Article] Biphenyl ether derivatives with protein tyrosine phosphatase 1B inhibitory activity from a freshwater fungus Phoma sp.2017
- Author(s)
  Sumilat, D.A.; Yamazaki, H.; Kanno, S.; Saito, R.; Watanabe, Y.; Namikoshi, M.
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 3 Pages: 331-333
- DOI
  10.1038/ja.2016.147
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp.2017
- Author(s)
  Abdjul Delfly B.、Yamazaki Hiroyuki、Kanno Syu-ichi、Tomizawa Ayako、Rotinsulu Henki、Wewengkang Defny S.、Sumilat Deiske A.、Ukai Kazuyo、Kapojos Magie M.、Namikoshi Michio
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 71 Issue: 3 Pages: 531-536
- DOI
  10.1007/s11418-017-1085-6
- NAID
  40021218301
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] A New Pyranonaphtoquinone Derivative, 4-Oxo-rhinacanthin A, from Roots of Indonesian Rhinacanthus nasutus2017
- Author(s)
 Maarisit Wilmar、Yamazaki Hiroyuki、Abdjul Delfly Booby、Takahashi Ohgi、Kirikoshi Ryota、Namikoshi Michio
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 65 Issue: 6 Pages: 586-588
- DOI
 10.1248/cpb.c17-00074
- NAID
 130005686030
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-16K21310
[Journal Article] Lissoclibadin 1, a polysulfur aromatic alkaloid obtained from the Indonesian ascidian Lissoclinum cf. badium, induces caspase-dependent apoptosis in human colon cancer cells and suppresses tumor growth in nude mice.2017
- Author(s)
  Tatsuta, T.; Hosono, M.; Namikoshi, M.; Rotinsulu, H.; Wewengkang, D.S.; Sumilat, D.A.; Yamazaki, H.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 80 Issue: 2 Pages: 499-502
- DOI
  10.1021/acs.jnatprod.6b01051
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] A tetramic acid derivative with protein tyrosine phosphatase 1B inhibitory activity and a new nortriterpene glycoside from the Indonesian marine sponge Petrosia sp.2017
- Author(s)
  Maarisit, W.; Yamazaki, H.; Kanno, S.; Tomizawa, A.; Rotinsulu, H.; Wewengkang, D. S.; Sumilat, D. A.; Ukai, K.; Kapojos, M. M.; Namikoshi, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 27 Issue: 4 Pages: 999-1002
- DOI
  10.1016/j.bmcl.2016.12.077
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] A bromopyrrole-containing diterpene alkaloid from the Okinawan marine sponge Agelas nakamurai activates the insulin pathway in Huh-7 human hepatoma cells by inhibiting protein tyrosine phosphatase 1B2017
- Author(s)
  Yamazaki Hiroyuki、Kanno Syu-ichi、Abdjul Delfly B.、Namikoshi Michio
- Journal Title
  
  Bioorganic & medicinal chemistry letters
  
  Volume: 27 Issue: 10 Pages: 2207-2209
- DOI
  10.1016/j.bmcl.2017.03.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] A 2,4′-linked tetrahydroxanthone dimer with protein tyrosine phosphatase 1B inhibitory activity from the Okinawan freshwater Aspergillus sp.2017
- Author(s)
  Rotinsulu Henki、Yamazaki Hiroyuki、Miura Tomohito、Chiba Satomi、Wewengkang Defny S、Sumilat Deiske A、Namikoshi Michio
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 70 Issue: 9 Pages: 967-969
- DOI
  10.1038/ja.2017.72
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Oleanane triterpenes with protein tyrosine phosphatase 1B inhibitory activity from aerial parts of Lantana camara collected in Indonesia and Japan2017
- Author(s)
  Abdjul Delfly B.、Yamazaki Hiroyuki、Maarisit Wilmar、Rotinsulu Henki、Wewengkang Defny S.、Sumilat Deiske A.、Kapojos Magie M.、Losung Fitje、Ukai Kazuyo、Namikoshi Michio
- Journal Title
  
  Phytochemistry
  
  Volume: 144 Pages: 106-112
- DOI
  10.1016/j.phytochem.2017.08.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida.2017
- Author(s)
  Maarisit, W.; Yamazaki, H.; Kanno, S.; Tomizawa, A.; Lee, J.-S.; Namikoshi, M.
- Journal Title
  
  J. Nat. Med.
  
  Volume: 71 Issue: 1 Pages: 334-337
- DOI
  10.1007/s11418-016-1061-6
- NAID
  40021062945
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Anti-mycobacterial alkaloids, cyclic 3-alkyl pyridinium dimers, from the Indonesian marine sponge Haliclona sp.2017
- Author(s)
  Maarisit Wilmar、Abdjul Delfly B.、Yamazaki Hiroyuki、Kato Hajime、Rotinsulu Henki、Wewengkang Defny S.、Sumilat Deiske A.、Kapojos Magie M.、Ukai Kazuyo、Namikoshi Michio
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 15 Pages: 3503-3506
- DOI
  10.1016/j.bmcl.2017.05.067
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Furanoterpenes, new types of protein tyrosine phosphatase 1B inhibitors, from two Indonesian marine sponges, Ircinia and Spongia spp.2017
- Author(s)
  Abdjul, D. B.; Yamazaki, H.; Kanno, S.; Wewengkang, D. S.; Rotinsulu, H.; Sumilat, D. A.; Ukai, K.; Namikoshi, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 27 Issue: 5 Pages: 1159-1161
- DOI
  10.1016/j.bmcl.2017.01.071
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Eudesmanolide sesquiterpenes and protein tyrosine phosphatase 1B inhibitory ent-kaurene diterpenes from aerial parts of Indonesian Wedelia prostata2017
- Author(s)
  Abdjul Delfly B.、Yamazaki Hiroyuki、Maarisit Wilmar、Losung Fitje、Rotinsulu Henki、Wewengkang Defny S.、Sumilat Deiske A.、Namikoshi Michio
- Journal Title
  
  Phytochemistry Letters
  
  Volume: 20 Pages: 191-195
- DOI
  10.1016/j.phytol.2017.04.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] A new biphenyl ether derivative produced by Indonesian ascidian-derived Penicillium albobiverticillium2017
- Author(s)
  Sumilat Deiske A.、Yamazaki Hiroyuki、Endo Kotaro、Rotinsulu Henki、Wewengkang Defny S.、Ukai Kazuyo、Namikoshi Michio
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 71 Issue: 4 Pages: 776-779
- DOI
  10.1007/s11418-017-1094-5
- NAID
  40021338063
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Sesquiterpene hydroquinones with protein tyrosine phosphatase 1B inhibitory activities from a Dysidea sp. marine sponge collected in Okinawa.2016
- Author(s)
  Abdjul, D.B.; Yamazaki, H.; Takahashi, O.; Kirikoshi, R.; Ukai, K.; Namikoshi, M.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 79 Issue: 7 Pages: 1842-1847
- DOI
  10.1021/acs.jnatprod.6b00367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Isopetrosynol, a new protein tyrosine phosphatase 1B inhibitor, from the marine sponge Halichondria cf. panicea collected at Iriomote Island.2016
- Author(s)
  Abdjul, D.B., Yamazaki, H., Takahashi, O., Kirikoshi, R., Ukai, K., Namikoshi, M.
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 64
- NAID
  130005160060
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Asperdichrome, an unusual dimer of tetrahydroxanthone through an ether bond, with protein tyrosine phosphatase 1B inhibitory activity, from the Okinawan freshwater Aspergillus sp. TPU1343.2016
- Author(s)
  Yamazaki, H., Ukai, K., Namikoshi, M.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 57 Issue: 7 Pages: 732-735
- DOI
  10.1016/j.tetlet.2015.12.111
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Induced production of a new modified dipeptide with a disufide bridge by the long-term fermentation of a marine-derived Trichoderma cf. brevicompactum.2016
- Author(s)
  Yamazaki, H.; Rotinsulu, H.; Takahashi, O.; Kirikoshi, R.; Namikohsi, M.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 57 Issue: 51 Pages: 5764-5767
- DOI
  10.1016/j.tetlet.2016.11.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Halichlonadiamine derivatives and 6-epi-monanchorin from the marine sponge Halichondria panicea collected at Iriomote Island.2016
- Author(s)
  Abdjul, D.B.; Yamazaki, H.; Kanno, S.; Takahashi, O.; Kirikoshi, R.; Ukai, K.; Namikoshi, M.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 79 Issue: 4 Pages: 1149-1154
- DOI
  10.1021/acs.jnatprod.6b00095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21310
[Journal Article] Structures and biological activities of triterpenes and sesquiterpenes obtained from Russula lepida.2016
- Author(s)
  Lee, J.-S., Maarisit, W., Abdjul, D.B., Yamazaki, H., Takahashi, O., Kirikoshi, R., Kanno, S., Namikoshi, M.
- Journal Title
  
  Phytochemistry
  
  Volume: 127 Pages: 63-68
- DOI
  10.1016/j.phytochem.2016.03.014
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Penicyrones A and B, an epimeric pair of α-pyrone-type polyketides from the marine-derived Penicillium sp.2016
- Author(s)
  Bu, Y.-Y., Yamazaki, H., Takahashi, O., Kirikoshi, R., Ukai, K., Namikoshi, M.
- Journal Title
  
  J. Antibiot.
  
  Volume: 69 Issue: 1 Pages: 57-61
- DOI
  10.1038/ja.2015.82
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Isopetrosynol, a New Protein Tyrosine Phosphatase 1B Inhibitor, from the Marine Sponge Halichondria cf. panicea Collected at Iriomote Island2016
- Author(s)
 Abdjul, D.B.; Yamazaki, H.; Takahashi, O.; Kirikoshi, R.; Ukai, K.; Namikoshi, M.
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 64 Issue: 7 Pages: 733-736
- DOI
 10.1248/cpb.c16-00061
- NAID
 130005160060
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K21310
[Journal Article] A dimeric urea of the bisabolene sesquiterpene from the Okinawan marine sponge Axinyssa sp. inhibits protein tyrosine phosphatase 1B activity in Huh-7 human hepatoma cells.2016
- Author(s)
  Abdjul, D. B., Kanno, S., Yamazaki, H., Ukai, K. Namikoshi, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Issue: 2 Pages: 315-317
- DOI
  10.1016/j.bmcl.2015.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Absolute structures and bioactivity of euryspongins and eurydiene obtained a marine sponge Euryspongia sp. collected at Iriomote Island.2015
- Author(s)
  Yamazaki, H., Takahashi, O., Kanno, S., Nakazawa, T., Takahashi, S., Ukai, K., Sumilat, D.A., Ishikawa, M., and Namikoshi M.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 4 Pages: 797-802
- DOI
  10.1016/j.bmc.2014.12.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Penicillimide, an open-chain hemisuccinimide from Okinawan marine-derived Penicillium copticola.2015
- Author(s)
  Bu, Y.-Y., Yamazaki, H., Ukai, K., and Namikoshi, M
- Journal Title
  
  J. Antibiot.
  
  Volume: in press Issue: 8 Pages: 537-539
- DOI
  10.1038/ja.2015.21
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Induced production of halogenated epidithiodiketopiperazines by a marine-derived Trichoderma cf. brevicompactum with sodium halides.2015
- Author(s)
  Yamazaki, H., Rotinsulu, H., Narita, R., Takahashi, R., Namikoshi, M.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 78 Issue: 10 Pages: 2319-2321
- DOI
  10.1021/acs.jnatprod.5b00669
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Two new protein tyrosine phosphatase 1B inhibitors, hyattellactones A and B, from an Indonesian marine sponge Hyattella sp.2015
- Author(s)
  Abdjul, D.B., Yamazaki, H., Takahashi, O., Kirikoshi, R., Mangindaan, R.E.P., and Namikoshi, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 4 Pages: 904-907
- DOI
  10.1016/j.bmcl.2014.12.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Two new indole derivatives from a marine sponge Ircinia sp. collected at Iriomote Island.2015
- Author(s)
  Abdjul, D.B., Yamazaki, H., Ukai, K., and Namikoshi, M.
- Journal Title
  
  J. Nat. Med.
  
  Volume: in press Issue: 3 Pages: 416-420
- DOI
  10.1007/s11418-015-0891-y
- NAID
  40020494459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Verruculides A and B, two new protein tyrosine phosphatase 1B inhibitors from an Indonesian ascidian-derived Penicillium verruculosum.2015
- Author(s)
  Yamazaki H., Nakayama, W., Takahashi, O., Kirikoshi, R., Izumikawa, R., Iwasaki, K., Toraiwa, K., Rotinsulu, H., Wewengkang, D. S., Sumilat, D. A., Mangindaan, R. E. P., Namikoshi, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 16 Pages: 3087-3090
- DOI
  10.1016/j.bmcl.2015.06.026
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Structures and biological evaluations of agelasines isolated from the Okinawan marine sponge Agelas nakamurai.2015
- Author(s)
  Abdjul, D. B., Yamazaki, H., Kanno, S., Takahashi, O., Kirikoshi, R., Ukai, K., Namikoshi, M.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 78 Issue: 6 Pages: 1428-1433
- DOI
  10.1021/acs.jnatprod.5b00375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Induced production of a new unprecedented epitrithiodiketopiperazine, chlorotrithiobrevamide, by a culture of the marine-derived Trichoderma cf. brevicompactum with dimethyl sulfoxide.2015
- Author(s)
  Yamazaki, H., Takahashi, O., Murakami, K., Namikoshi, M.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 56 Issue: 45 Pages: 2319-2321
- DOI
  10.1016/j.tetlet.2015.09.113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Trichoketides A and B, two new protein tyrosine phosphatase 1B inhibitors from the marine-derived fungus Trichoderma sp.2015
- Author(s)
  Yamazaki, H., Saito, R., Takahashi, O., Kirikoshi, R., Toraiwa, K.; Iwasaki, K., Izumikawa, Y., Nakayama, W., Namikoshi, M.
- Journal Title
  
  J. Antibiot.
  
  Volume: 68 Issue: 10 Pages: 628-632
- DOI
  10.1038/ja.2015.44
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Strongylophorines, new protein tyrosine phosphatase 1B inhibitors, from the marine sponge Strongylophora strongilata collected at Iriomote Island.2015
- Author(s)
  Lee, J.-S., Abdjul, D. B., Yamazaki, H., Takahashi, O., Kirikoshi, R., Ukai, K., Namikoshi, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 18 Pages: 3900-3902
- DOI
  10.1016/j.bmcl.2015.07.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Quest of protein tyrosine phosphatase 1B inhibitors from aquatic fungi collected in Aomori.2014
- Author(s)
  Chida, K., Saito, R., Yamazaki, H., Kanno, S., Ishikawa, M., and Namikoshi, M.
- Journal Title
  
  J. Tohoku Phrarm. Univ.
  
  Volume: 61 Pages: 35-39
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Anti-mycobacterial Nucleoside Antibiotics from a Marine-Derived Streptomyces sp. TPU1236A.2014
- Author(s)
  Bu, Y.-Y., Yamazaki, H., Ukai, K., and Namikoshi, M.
- Journal Title
  
  Mar. Drugs
  
  Volume: 12 Issue: 12 Pages: 6102-6112
- DOI
  10.3390/md12126102
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25870660
[Journal Article] Papuamine and haliclonadiamine, obtained from an Indonesian sponge Haliclona sp2012
- Author(s)
  H. Yamazaki, D. S. Wewengkang, S. Kanno, M. Ishikawa, Henki Rotinsulu, R. E. P. Mangindaan, M. Namikoshi
- Journal Title
  
  Nat. Prod. Res
  
  Volume: (in press) Issue: 11 Pages: 1012-1015
- DOI
  10.1080/14786419.2012.688050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603012
[Journal Article] Two New Tryptamine Derivatives, Leptoclinidamide and(-)-Leptoclinidamine B from an Indonesian Ascidian Leptoclinides dubius2012
- Author(s)
  H. Yamazaki, D. S. Wewengkang, T. Nishikawa, H. Rotinsulu, R. E. P. Mangindaan, M. Namikoshi
- Journal Title
  
  Mar. Drugs
  
  Volume: 10 Issue: 2 Pages: 349-357
- DOI
  10.3390/md10020349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] Anti-mycobacterial activity of secondary metabolites from the marine sponge Agelas sp.2023
- Author(s)
  Wilmar Maarisit, Sonny D. Untu, Yessie K. Lengkey, Hiroyuki Yamazaki, Michio Namikoshi, Fitje Losung, Veibe Warouw
- Organizer
  The 8th International Symposium on Biomedical Engineering
- Data Source
  KAKENHI-PROJECT-21K06631
[Presentation] UV absorbing substances in the Indonesian starfish Archaster typicus2022
- Author(s)
  Delfly B. Abdjul, Magie Kapojos, Hiroyuki Yamazaki, Michio Namikoshi
- Organizer
  9th International Conference on Sustainable Agriculture and Environment
- Data Source
  KAKENHI-PROJECT-21K06631
[Presentation] Screening for PTP1B inhibitors from Indonesian edible plants2019
- Author(s)
  Magie M. Kapojos, Delfly B. Abdjul, Hiroyuki Yamazaki, Akiho Yagi, Ryuji Uchida
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-17KK0173
[Presentation] Screening for PTP1B inhibitors from Indonesian edible plants2019
- Author(s)
  Magie M. Kapojos, Delfly B. Abdjul, Hiroyuki Yamazaki, Akiho Yagi, Ryuji Uchida
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] Isolation and characterization of small molecule inhibitors of BMP induced osteoblastic differentiation from the Indonesian marine sponge2018
- Author(s)
  Satoshi Ohte, Hiroyuki Yamazaki, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Ryuji Uchida, Michio Namikoshi, Takenobu Katagiri, Hiroshi Tomoda
- Organizer
  12th International BMP conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] Anti-mycobacterial activity from the marine sponge Haliclona sp.2018
- Author(s)
  Wilmar Maarisit, Hiroyuki Yamazaki, Kazuyo Ukai, Michio Namikoshi
- Organizer
  1st International Seminar on Pharmaceutical 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] Isolation and characterization of small molecule inhibitors of BMP induced osteoblastic differentiation from the Indonesian marine sponge2018
- Author(s)
  Satoshi Ohte, Hiroyuki Yamazaki, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Ryuji Uchida, Michio Namikoshi, Takenobu Katagiri, Hiroshi Tomoda
- Organizer
  12th International BMP conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0173
[Presentation] Anti-mycobacterial activity from the marine sponge Haliclona sp.2018
- Author(s)
  Wilmar Maarisit, Hiroyuki Yamazaki, Kazuyo Ukai, Michio Namikoshi
- Organizer
  1st International Seminar on Pharmaceutical 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0173
[Presentation] Structures and biological activities of alkyl pyridinium alkaloids from an unidentified Indonesian marine sponge2017
- Author(s)
  Wilmar Maarisit, Delfly B. Abdjul, Hiroyuki Yamazaki, Hajime Kato, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Kazuyo Ukai, Magie M. Kapojos, Michio Namikoshi
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  東北大学(宮城県仙台市)
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] An anti-mycobacterial sphingolipid and a new bromopyrrol alkaloid from an unidentified Indonesian marine sponge2017
- Author(s)
  Delfly B. Abdjul, Hiroyuki Yamazaki, Syu-ichi Kanno, Ayako Tomizawa, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Kazuyo Ukai, Magie M. Kapojos, Michio Namikoshi
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  東北大学(宮城県仙台市)
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] Structures and biological activities of new terpene metabolites obtained from the fruiting bodies of Russula lepida.2016
- Author(s)
  Jong-Soo Lee, Wilmar Maarisit, Delfly B. Abdjul, Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Syu-ichi Kanno, and Michio Namikoshi
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] New sesquiterpene lactones from the aerial parts of Indonesian Wedelia prostata2016
- Author(s)
  Delfly B. Abdjul, Hiroyuki Yamazaki, Syu-ichi Kanno, Wilmar Maarisit, Fitje Losung, Henki Rotinsulua, Defny S. Wewengkanga, Deiske A. Sumilat, Michio Namikoshi
- Organizer
  第55回日本薬学会東北支部大会
- Place of Presentation
  奥羽大学(福島県郡山市)
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] インドネシア産海洋糸状菌Penicillium verruculosum TPU1311株が生産する新規protein tyrosine phosphatase 1B阻害剤verruculide類に関する研究2016
- Author(s)
  山崎寛之, 高橋央宜, 桐越亮太, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, 鵜飼和代, 浪越通夫
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] パラオ産海洋糸状菌 Trichoderma cf. brevicompactumTPU199株のジメチルスルフォキシド添加培養によるchlorotrithiobrevamideの生産誘導2016
- Author(s)
  山崎寛之, 高橋央宜, 村上一輝, 浪越通夫
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] 海洋糸状菌Penicillium sp. TPU1271株が生産するポリケタイド化合物penicyrones AおよびBに関する研究2016
- Author(s)
  卜英悦, 山崎寛之, 高橋央宜, 桐越亮太, 鵜飼和代, 浪越通夫
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Search for protein tyrosine phosphatase 1B inhibitors from an Indonesian marine sponge Petrosia sp.2016
- Author(s)
  Wilmar Maarisit, Hiroyuki Yamazaki, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Kazuyo Ukai, Michio Namikoshi
- Organizer
  第55回日本薬学会東北支部大会
- Place of Presentation
  奥羽大学(福島県郡山市)
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] A new polyacetylene derivative with protein tyrosine phosphatase 1B inhibitory activity from the marine sponge Halicondria cf. panicea collected at Iriomote Island2016
- Author(s)
  Delfly B. Abdjul, Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Kazuyo Ukai, and Michio Namikoshi
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] 天然由来化合物ライブラリーを基盤とした抗結核剤の探索2016
- Author(s)
  中原悠太, 田中有理沙, 郡司雅奈子, Delfly B. Abdjul, 山崎寛之, 小山信裕, 浪越通夫, 供田洋
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Structures and PTP1B inhibitory activities of triterpenes and sesquiterpenes obtained from Russula lepida2016
- Author(s)
  Wilmar Maarisit, Jong-Soo Lee, Delfly B. Abdjul, Hiroyuki Yamazaki, Syu-ichi Kanno, Ohgi Takahashi, Ryota Kirikoshi, Michio Namikoshi
- Organizer
  第58回天然有機化合物討論会
- Place of Presentation
  東北大学(宮城県仙台市)
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] Sesquiterpene hydroquinones with protein tyrosine phosphatase 1B inhibitory activities from a marine sponge Dysidea sp. collected at Iriomote Island2016
- Author(s)
  Delfly B. Abdjul, Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Kazuyo Ukai, Michio Namikoshi
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉大学(千葉県千葉市)
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K21310
[Presentation] 有用天然成分の探索と有効利用2015
- Author(s)
  山崎寛之, 鵜飼和代, 浪越通夫
- Organizer
  産学官連携フェア2015みやぎ
- Place of Presentation
  仙台国際センター (宮城県仙台市)
- Year and Date
  2015-12-09
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] 西表島産海綿より見出した新規agelasine類の構造と抗結核活性2015
- Author(s)
  Delfly B. Abdjula, 山崎寛之, 高橋央宜, 桐越亮太, 浪越通夫
- Organizer
  日本薬学会第135回年会
- Place of Presentation
  デザインクリエイティブセンター神戸(兵庫県神戸市)
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Polycyclic alkaloids from the marine sponge Halichondria panicea collected at Iriomote Island2015
- Author(s)
  Delfly B. Abdjul, Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Kazuyo Ukai, Michio Namikoshi
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  岩手医科大学 (岩手県矢巾町)
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] インドネシア産放線菌が生産する二次代謝産物に関する研究2015
- Author(s)
  山崎寛之, 遠藤幸太郎, 小笠原彰希, 高橋萌, 渡辺祐太, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, 鵜飼和代, 浪越通夫
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  岩手医科大学 (岩手県矢巾町)
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] 西表島産海綿 Halichondria panicea より得られた新規 halichondriamines の構造と生物活性2015
- Author(s)
  Delfly B. Abdjul, 山崎寛之, 菅野秀一, 高橋央宜, 桐越亮太, 鵜飼和代, 浪越通夫
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  神奈川県民ホール (神奈川県横浜市)
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] インドネシア産薬用植物Rhinacanthus nasutusの化学成分の単離と生物活性2015
- Author(s)
  Wilmar Maarisit, 山崎寛之, Delfly B. Abdjul, 浪越通夫
- Organizer
  日本薬学会第135回年会
- Place of Presentation
  デザインクリエイティブセンター神戸(兵庫県神戸市)
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Isolation and structure of a new chemical constituent from an Indonesian medicinal plant Rhinacanthus nasutus2015
- Author(s)
  Wilmar Maarisit, Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Michio Namikoshi
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  岩手医科大学 (岩手県矢巾町)
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] 海洋生物資源を対象としたprotein tyrosine phosphatase 1B阻害剤の探索と培養法検討による新規糸状菌二次代謝産物の誘導生産2015
- Author(s)
  山崎寛之, 浪越通夫
- Organizer
  第6回食品薬学シンポジウム
- Place of Presentation
  岡山大学 (岡山県岡山市)
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Induced production of new epidithiodiketopiperazines by the Palauan marine-derived fungus Trichoderma sp. TPU1992015
- Author(s)
  Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Michio Namikoshi
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Marine natural products with protein tyrosine phosphatase 1B inhibitory activity2015
- Author(s)
  Hiroyuki Yamazaki, Syu-ichi Kanno, Ohgi Takahashi, Ryota Kirikoshi, Delfly B. Abdjul, Kazuyo Ukai, Henki Rotinsulu, Defny S. Wewengkang, Deiske, A. Sumilat, Remy E. P. Mangindaan, Michio Namikoshi
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] Isolation and structures of new indole derivatives from a marine sponge collected at Iriomote island.2014
- Author(s)
  Delfly B. Abdjul, Hiroyuki Yamazaki, Kazuyo Ukai, and MichioNamikoshi
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  いわき明星大学(福島県いわき市)
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25870660
[Presentation] 海洋天然物13種のV79細胞に対する細胞障害性について2012
- Author(s)
  小田泰子、北村美里、山崎寛之、R.E.P.Mangindaan、浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] Bioactive Compounds from Indonesian Ascidian Leptoclinides dubius and Marine Sponge Haliclona sp2012
- Author(s)
  H.Yamazaki, D.S.Wewengkang, S.Kanno, T.Nishikawa, H.Rotinsulu, M.Ishikawa, R.E.P.Mangindaan, M.Namikoshi
- Organizer
  The 6th Korea-Japan Chemical Biology Symposium
- Place of Presentation
  札幌(定山渓花もみじ)
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] インドネシア産海綿から単離したpapuamine類のアポトーシス誘導作用2012
- Author(s)
  山崎寛之, 菅野秀一, D. S. Wewengkang, 石川正明、H. Rotinsulu, R. E. P. Mangindaan, 浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] インドネシア産海綿から単離したpapuamine類のアポトーシス誘導作用2012
- Author(s)
  山崎寛之、菅野秀一、D.S.Wewengkang、石川正明、H.Rotinsulu、R.E.P.Mangindaan、浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] インドネシア産群体ボヤから単離した新規インドールアルカロイドの構造2012
- Author(s)
  山崎寛之、D.S.Wewengkang、西川輝昭、H.Rotinsulu、R.E.P.Mangindaan、浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] 海洋天然物13種のV79細胞に対する細胞障害性について2012
- Author(s)
  小田泰子, 北村美里, 山崎寛之, R. E. P. Mangindaan, 浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] Bioactive Compounds from Indonesian Ascidian Leptoclinides dubius and Marine Sponge Haliclona sp2012
- Author(s)
  H. Yamazaki, D. S. Wewengkang, S. Kanno, T. Nishikawa, H. Rotinsulu, M. Ishikawa, R. E. P. Mangindaan, M. Namikoshi
- Organizer
  The 6th Korea-Japan Chemical Biology Symposium
- Place of Presentation
  札幌
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] インドネシア産群体ボヤから単離した新規インドールアルカロイドの構造2012
- Author(s)
  山崎寛之、D. S. Wewengkang、西川輝昭、H. Rotinsulu、R. E. P. Mangindaan、浪越通夫、
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] 炎症性サイトカイン産生系に効果を示す海洋天然物の探索2012
- Author(s)
  小田泰子、北村美里、山崎寛之、R.E.P.Mangindaan、浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] 炎症性サイトカイン産生系に効果を示す海洋天然物の探索2012
- Author(s)
  小田泰子, 北村美里, 山崎寛之, R. E. P. Mangindaan, 浪越通夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21603012
[Presentation] インドネシア産単体ボヤから単離した新規化合物の構造2011
- Author(s)
  山崎寛之, D. S. Wewengkang, H. Rotinsulu, R. E. P. Mangindaan, 塚本佐知子、浪越通夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21603012

1. NAMIKOSHI Michio (30189196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. NAKAZAWA Takahiro (60296019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. UKAI Kazuyo (60433512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大城太一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 供田洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamazaki Hiroyuki 山崎 寛之

YAMAZAKI Hiroyuki 山崎 寛之

Research Projects

Research Products

Co-Researchers

特殊微生物と特殊培養法の融合による新規二次代謝産物の生産Principal Investigator

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特殊微生物を活用した培養法の確立と新規二次代謝産物の創出Principal Investigator

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Study on various culture investigations for rare marine-derived microorganismsPrincipal Investigator

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Development of induced production method for dormant fungal secondary metabolites with a combination of chemical epigenetics and several culture conditionsPrincipal Investigator

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Development of induced production method for dormant fungal secondary biogenesis by modulating new epigenetic targetsPrincipal Investigator

Principal Investigator

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Studies on the mechanisms of anticancer and anti-inflammatory activities of alkaloids from ascidians

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[Journal Article] Evaluation on bioactivity of ascidian collected in North Sulawesi as seeds of marine-derived drugs2023

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[Journal Article] Anti-mycobacterial activity of polycarpine and polycarpaurine A from an Indonesia marine ascidian Polycarpa sp.2023

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[Journal Article] Exploration of marine natural resources in Indonesia and development of efficient strategies for the production of microbial halogenated metabolites2022

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NAID

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[Journal Article] New piericidin rhamnosides as potentiators of amphotericin B activity against Candida albicans produced by actinomycete strain TMPU-A02872022

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[Journal Article] Inhibitory effects of sesquiterpene lactones from the Indonesian marine sponge Lamellodysidea cf. herbacea on bone morphogenetic protein-induced osteoblastic differentiation2021

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DOI

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[Journal Article] Three Bioactive Compounds Against Colony Formation of Chinese Hamster V79 Cells from an Indonesian Ascidian Didemnum sp.2021

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DOI

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[Journal Article] Germacrane sesquiterpenes from leaves of Eupatorium chinense inhibit protein tyrosine phosphatase2021

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[Journal Article] Epipolythiodiketopiperazine and trichothecene derivatives from the NaI-containing fermentation of marine-derived Trichoderma cf. brevicompactum2020

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Yamazaki Hiroyuki 山崎寛之

YAMAZAKI Hiroyuki 山崎寛之