ISHIZAKI Reina 石崎怜奈

Researcher Number	70528299
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2023: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 心筋肥大 / PTPN11 / 肥大型心筋症 / Noonan症候群 / 心臓流出路異常 / 肺動脈発生 / 遺伝子改変マウス / 肺動脈平滑筋特異的マーカー / Tbx1 / 総動脈幹症 / 発生 / 肺動脈平滑筋 / IP3R2 … More Except Principal Investigator … More 先天性心疾患 / 遺伝子改変マウス / 遺伝子解析 / 心臓発生 / 葉酸 / Tbx20 / Tbx1 / 総動脈幹症 / 多因子遺伝 / シグナル伝達 / 発現制御 / 循環器・高血圧 / 遺伝子 / 発生・分化 Less

Oligogenic inheritance of congenital cardiac outflow tract abnormalities
- Principal Investigator
  
  内田敬子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University
モデル動物とiPS細胞を用いた心臓前駆細胞発生制御による予防医学的基礎研究
- Principal Investigator
  
  山岸敬幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University
Molecular mechanism of myocardial hypertrophy caused by PTPN11 mutation in Noonan's syndromePrincipal Investigator
- Principal Investigator
  
  Ishizaki Reina
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University
Inositol 1,4,5- trisphosphate receptor 2 as a novel pulmonary artery smooth muscle marker to delineate the processes of cardiopulmonary developmentPrincipal Investigator
- Principal Investigator
  
  ISHIZAKI Reina
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University

All 2024 2023 2020 2019

All Journal Article Presentation

[Journal Article] The c.1617del variant of TMEM260 is identified as the most frequent single gene determinant for Japanese patients with a specific type of congenital heart disease2024
- Author(s)
  Inoue Tadashi、Takase Ryuta、Uchida Keiko、Kodo Kazuki、Suda Kenji、Watanabe Yoriko、Yoshiura Koh-Ichiro、Kunimatsu Masaya、Ishizaki Reina、Azuma Kenko、Inai Kei、Muneuchi Jun、Furutani Yoshiyuki、Akagawa Hiroyuki、Yamagishi Hiroyuki
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 69 Issue: 5 Pages: 215-222
- DOI
  10.1038/s10038-024-01225-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07275, KAKENHI-PROJECT-23K24306, KAKENHI-PROJECT-23K27572
[Journal Article] A genetic and developmental biological approach for a family with complex congenital heart diseases?evidence of digenic inheritance2023
- Author(s)
  Yoshida Yu、Uchida Keiko、Kodo Kazuki、Ishizaki-Asami Reina、Maeda Jun、Katsumata Yoshinori、Yuasa Shinsuke、Fukuda Keiichi、Kosaki Kenjiro、Watanabe Yusuke、Nakagawa Osamu、Yamagishi Hiroyuki
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10 Pages: 1135141-1135141
- DOI
  10.3389/fcvm.2023.1135141
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07275, KAKENHI-PROJECT-21H02890, KAKENHI-PROJECT-23K24061, KAKENHI-PROJECT-23K24306
[Journal Article] A lacZ Reporter Transgenic Mouse Line Revealing the Development of Pulmonary Artery2020
- Author(s)
  Ishizaki Reina、Uchida Keiko、Shibata Akimichi、Tsuchihashi Takatoshi、Maeda Jun、Mikoshiba Katsuhiko、Yamagishi Hiroyuki
- Journal Title
  
  Springer, Singapore
  
  Volume: - Pages: 83-85
- DOI
  10.1007/978-981-15-1185-1_9
- ISBN
  9789811511844, 9789811511851
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17309
[Presentation] 区域性肺高血圧症に対する肺高血圧治療薬の効果の違い2023
- Author(s)
  内田敬子，住友直文，石崎怜奈，福島裕之，石井卓，石田秀和，高月晋一，小垣滋豊，稲井慶，土井庄三郎，山岸敬幸
- Organizer
  第8回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07275
[Presentation] 先天性心疾患に伴う区域性肺高血圧症に対する薬物治療効果の検討2023
- Author(s)
  内田敬子，住友直文，石崎怜奈，福島裕之，石井卓，石田秀和，高月晋一，小垣滋豊，稲井慶，土井庄三郎，山岸敬幸
- Organizer
  第59回日本小児循環器学会総会・会学術集会
- Data Source
  KAKENHI-PROJECT-23K07275
[Presentation] Exploring Oligogenic Inheritance of Complex Congenital Heart Diseases Using Trio-Based Sequencing and Mouse Model Approaches2023
- Author(s)
  Uchida K, Yoshida Y, Kodo K, Ishizaki R, Kunimatsu M, Inoue T, Yamagishi H
- Organizer
  Weinstein Cardiovascular Development and Regeneration Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07275
[Presentation] The 1,4,5-trisphosphate receptor 2 as a novel marker of vasculature for delineating the cardiopulmonary development2019
- Author(s)
  Reina Ishizaki, Keiko Uchida, Akimichi Shibata, Kazuki Kodo, Takatoshi Tsuchihashi, Katsuhiko Mikoshiba, Hiroyuki Yamagishi
- Organizer
  2019 Weinstein Cardiovascular Development Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17309
[Presentation] イノシトール三リン酸受容体（2型）の心臓流出路・肺動脈発生マーカーとしての有用性2019
- Author(s)
  石崎怜奈、内田敬子、土橋隆俊、柴田映道、古道一樹、御子柴克彦、山岸敬幸
- Organizer
  第18回日本心臓血管発生研究会
- Data Source
  KAKENHI-PROJECT-19K17309

1. 内田敬子 (50286522)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 山岸敬幸 (40255500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 古道一樹 (10338105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 湯浅慎介 (90398628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISHIZAKI Reina 石崎 怜奈

Research Projects

Research Products

Co-Researchers

Oligogenic inheritance of congenital cardiac outflow tract abnormalities

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

モデル動物とiPS細胞を用いた心臓前駆細胞発生制御による予防医学的基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of myocardial hypertrophy caused by PTPN11 mutation in Noonan's syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inositol 1,4,5- trisphosphate receptor 2 as a novel pulmonary artery smooth muscle marker to delineate the processes of cardiopulmonary developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The c.1617del variant of TMEM260 is identified as the most frequent single gene determinant for Japanese patients with a specific type of congenital heart disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A genetic and developmental biological approach for a family with complex congenital heart diseases?evidence of digenic inheritance2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A lacZ Reporter Transgenic Mouse Line Revealing the Development of Pulmonary Artery2020

Author(s)

Journal Title

DOI

ISBN

Data Source

[Presentation] 区域性肺高血圧症に対する肺高血圧治療薬の効果の違い2023

Author(s)

Organizer

Data Source

[Presentation] 先天性心疾患に伴う区域性肺高血圧症に対する薬物治療効果の検討2023

Author(s)

Organizer

Data Source

[Presentation] Exploring Oligogenic Inheritance of Complex Congenital Heart Diseases Using Trio-Based Sequencing and Mouse Model Approaches2023

Author(s)

Organizer

Data Source

[Presentation] The 1,4,5-trisphosphate receptor 2 as a novel marker of vasculature for delineating the cardiopulmonary development2019

Author(s)

Organizer

Data Source

[Presentation] イノシトール三リン酸受容体（2型）の心臓流出路・肺動脈発生マーカーとしての有用性2019

Author(s)

Organizer

Data Source

ISHIZAKI Reina 石崎怜奈